se ha leído el artículo
array:24 [ "pii" => "S1578219020304224" "issn" => "15782190" "doi" => "10.1016/j.adengl.2019.02.029" "estado" => "S300" "fechaPublicacion" => "2021-01-01" "aid" => "2444" "copyright" => "AEDV" "copyrightAnyo" => "2020" "documento" => "simple-article" "crossmark" => 1 "licencia" => "http://creativecommons.org/licenses/by-nc-nd/4.0/" "subdocumento" => "crp" "cita" => "Actas Dermosifiliogr. 2021;112:77-9" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:1 [ "total" => 0 ] "itemSiguiente" => array:20 [ "pii" => "S1578219020303838" "issn" => "15782190" "doi" => "10.1016/j.adengl.2020.12.013" "estado" => "S300" "fechaPublicacion" => "2021-01-01" "aid" => "2457" "copyright" => "AEDV" "documento" => "simple-article" "crossmark" => 1 "licencia" => "http://creativecommons.org/licenses/by-nc-nd/4.0/" "subdocumento" => "crp" "cita" => "Actas Dermosifiliogr. 2021;112:79-80" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:1 [ "total" => 0 ] "en" => array:11 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Case and Research Letters</span>" "titulo" => "Cryptococcoid Sweet Syndrome: A Clinical and Histologic Imitator of Cryptococcosis" "tienePdf" => "en" "tieneTextoCompleto" => "en" "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "79" "paginaFinal" => "80" ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Síndrome de Sweet criptococoide: simulador de criptococosis tanto clínica como histológicamente" ] ] "contieneTextoCompleto" => array:1 [ "en" => true ] "contienePdf" => array:1 [ "en" => true ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:8 [ "identificador" => "fig0015" "etiqueta" => "Figure 3" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr3.jpeg" "Alto" => 629 "Ancho" => 750 "Tamanyo" => 110458 ] ] "detalles" => array:1 [ 0 => array:3 [ "identificador" => "at0015" "detalle" => "Figure " "rol" => "short" ] ] "descripcion" => array:1 [ "en" => "<p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">Immune staining with myeloperoxidase (hematoxylin–eosin, ×400).</p>" ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "M.E. Mazzei, A. Guerra, L. Dufrechou, M. Vola" "autores" => array:4 [ 0 => array:2 [ "nombre" => "M.E." "apellidos" => "Mazzei" ] 1 => array:2 [ "nombre" => "A." "apellidos" => "Guerra" ] 2 => array:2 [ "nombre" => "L." "apellidos" => "Dufrechou" ] 3 => array:2 [ "nombre" => "M." "apellidos" => "Vola" ] ] ] ] ] "idiomaDefecto" => "en" "Traduccion" => array:1 [ "es" => array:9 [ "pii" => "S0001731020303276" "doi" => "10.1016/j.ad.2019.03.022" "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:1 [ "total" => 0 ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0001731020303276?idApp=UINPBA000044" ] ] "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219020303838?idApp=UINPBA000044" "url" => "/15782190/0000011200000001/v1_202101161046/S1578219020303838/v1_202101161046/en/main.assets" ] "itemAnterior" => array:19 [ "pii" => "S1578219020303334" "issn" => "15782190" "doi" => "10.1016/j.adengl.2020.11.001" "estado" => "S300" "fechaPublicacion" => "2021-01-01" "aid" => "2437" "documento" => "simple-article" "crossmark" => 1 "licencia" => "http://creativecommons.org/licenses/by-nc-nd/4.0/" "subdocumento" => "crp" "cita" => "Actas Dermosifiliogr. 2021;112:75-7" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:1 [ "total" => 0 ] "en" => array:11 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Case and Research Letters</span>" "titulo" => "Borderline Tuberculoid Leprosy in Erythema Nodosum Leprosum Reaction Mimicking Sweet's Syndrome" "tienePdf" => "en" "tieneTextoCompleto" => "en" "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "75" "paginaFinal" => "77" ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Lepra tuberculoide borderline en paciente con reacción lepromatosa tipo eritema nudoso simulando un síndrome de Sweet" ] ] "contieneTextoCompleto" => array:1 [ "en" => true ] "contienePdf" => array:1 [ "en" => true ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:8 [ "identificador" => "fig0010" "etiqueta" => "Figure 2" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr2.jpeg" "Alto" => 759 "Ancho" => 1305 "Tamanyo" => 161103 ] ] "detalles" => array:1 [ 0 => array:3 [ "identificador" => "at0010" "detalle" => "Figure " "rol" => "short" ] ] "descripcion" => array:1 [ "en" => "<p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Histology showing infiltration of neutrophils, lymphocytes and plasma cells at the dermo-epidermal junction. Deeper dermis showing distorted epithelioid cell granulomas in fibrinoid necrosis and inflammatory infiltrate of neutrophils, lymphocytes, macrophages and plasma cells. (A- Original magnification X 100, B- Original magnification X 400, Haematoxylin and Eosin stain).</p>" ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "M. Pawar, V. Zawar, S. Kumavat" "autores" => array:3 [ 0 => array:2 [ "nombre" => "M." "apellidos" => "Pawar" ] 1 => array:2 [ "nombre" => "V." "apellidos" => "Zawar" ] 2 => array:2 [ "nombre" => "S." "apellidos" => "Kumavat" ] ] ] ] ] "idiomaDefecto" => "en" "Traduccion" => array:1 [ "es" => array:9 [ "pii" => "S0001731020302829" "doi" => "10.1016/j.ad.2020.08.001" "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:1 [ "total" => 0 ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0001731020302829?idApp=UINPBA000044" ] ] "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219020303334?idApp=UINPBA000044" "url" => "/15782190/0000011200000001/v1_202101161046/S1578219020303334/v1_202101161046/en/main.assets" ] "en" => array:16 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Case and Research Letters</span>" "titulo" => "Discoid Lupus Erythematosus in a Patient With Alopecia Totalis" "tieneTextoCompleto" => true "saludo" => "Dear Editor:" "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "77" "paginaFinal" => "79" ] ] "autores" => array:1 [ 0 => array:4 [ "autoresLista" => "M. Yamamoto, T. Yamamoto" "autores" => array:2 [ 0 => array:4 [ "nombre" => "M." "apellidos" => "Yamamoto" "email" => array:1 [ 0 => "toyamade@fmu.ac.jp" ] "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "*" "identificador" => "cor0005" ] ] ] 1 => array:2 [ "nombre" => "T." "apellidos" => "Yamamoto" ] ] "afiliaciones" => array:1 [ 0 => array:2 [ "entidad" => "Departamento de Dermatología, Universidad Médica de Fukushima, Fukushima, Japan" "identificador" => "aff0005" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "⁎" "correspondencia" => "Corresponding author." ] ] ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Lupus eritematoso discoide en una paciente con alopecia totalis" ] ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:8 [ "identificador" => "fig0005" "etiqueta" => "Figure 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 943 "Ancho" => 1255 "Tamanyo" => 210242 ] ] "detalles" => array:1 [ 0 => array:3 [ "identificador" => "at0005" "detalle" => "Figure " "rol" => "short" ] ] "descripcion" => array:1 [ "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">(a) Alopecia totalis on the scalp and erythema scattered on the cheek, nose, and lips. (b) Infiltrative erythemas on the upper cheek. (c) A biopsy specimen showing epidermal atrophy, liquefaction of the basement membrane, dyskeratotic epidermal cells, and focal mononuclear cell infiltration in the dermis.</p>" ] ] ] "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">We herein describe a rare case of discoid lupus erythematosus (DLE) in a patient with alopecia totalis.</p><p id="par0010" class="elsevierStylePara elsevierViewall">A 42-year-old female developed alopecia on the scalp, which worsened and involved all areas of the scalp 10 years previously. She received various treatments, such as topical corticosteroids, topical carpronium chloride, oral prednisolone, intra-lesional triamcinolone acetonide, and cryotherapy, for five years without success, and thus discontinued therapy a few years previously. She visited the dermatology clinic at Hanawa Kousei Hospital, complaining of asymptomatic facial erythemas which appeared one year previously. Physical examination revealed infiltrative scaly erythemas on the cheek, nose, lips, and upper back (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>a,b). Total alopecia of the scalp was also observed (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>a). Her eyebrows fell out, while the eyelashes remained intact. Laboratory examination showed positive anti-nuclear antibody (ANA) (1:1280, speckled), whereas other data such as complete blood count, liver and renal function, serum complement levels, anti-double strand DNA antibody, anti-Sm antibody, anti-SS-A antibody, anti-SS-B antibody, and antiphospholipid antibody were all within normal range. A biopsy specimen taken from the cheek revealed individual cell keratinization, liquefaction of epidermal basal membranes, and focal mononuclear cell infiltration in the dermis (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>c). Examination by direct immunofluorescence showed linear deposition of IgG, IgM, and C3. A diagnosis of DLE was made. Facial and back erythemas much improved by oral hydroxychloroquine (Plaquenil<span class="elsevierStyleSup">R</span>, Sanofi, Swiss) (200 mg and 400 mg per alternate day) six months later; however, her alopecia remained unchanged.</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><p id="par0015" class="elsevierStylePara elsevierViewall">Our patient suffering alopecia totalis developed DLE with nearly nine years’ interval, and alopecia was already stable when the DLE lesions appeared. Her scalp alopecia was non-scarring without erythema, and was therefore not identified as lupus alopecia, although biopsy was not carried out. Alopecia areata is sometimes associated with other autoimmune or allergic diseases, and there has been increased incidence of alopecia areata and lupus erythematosus.<a class="elsevierStyleCrossRefs" href="#bib0005"><span class="elsevierStyleSup">1,2</span></a> To date, several cases of DLE in association with alopecia have been reported.<a class="elsevierStyleCrossRefs" href="#bib0015"><span class="elsevierStyleSup">3,4</span></a> Among patients with severe types of alopecia such as alopecia totalis and universalis, thyroid disease was most prevalent, followed by vitiligo, diabetes, atopic dermatitis, dyslipidemia, hypertension, psoriasis, and internal malignancy.<a class="elsevierStyleCrossRef" href="#bib0025"><span class="elsevierStyleSup">5</span></a> However, to our knowledge, co-existence of DLE and alopecia totalis has not yet been reported. The present case showed a high titer of ANA (1:1280), suggesting that immunological abnormalities may have developed the DLE. She did not have any other specific autoantibodies, or other symptoms suggestive of systemic autoimmune diseases. Regarding the pathogenesis of alopecia areata, Th2 type cytokine predominance is seen in localized type while Th1 predominance in generalized type.<a class="elsevierStyleCrossRef" href="#bib0010"><span class="elsevierStyleSup">2</span></a> Furthermore, recent findings suggest an important role of IL-17 in alopecia;<a class="elsevierStyleCrossRef" href="#bib0030"><span class="elsevierStyleSup">6</span></a> however, the role of Th17 cells in DLE remains unclear. The cutaneous inflammatory infiltrates are dominated by Th1, but not Th17 cells, in the DLE lesion.<a class="elsevierStyleCrossRef" href="#bib0035"><span class="elsevierStyleSup">7</span></a> A genome-wide study has suggested that several genomic regions are significantly associated with alopecia areata, lupus erythematosus, and other autoimmune diseases. Such immune-mediated imbalance may have contributed to the development of alopecia totalis and DLE in our case. The facial lesions of our patient were eventually improved with hydroxychloroquine, which did not show any effects on the alopecia lesions.</p><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0005">Conflict of interests</span><p id="par0020" class="elsevierStylePara elsevierViewall">The authors declare that they have no conflict of interest.</p></span></span>" "textoCompletoSecciones" => array:1 [ "secciones" => array:2 [ 0 => array:2 [ "identificador" => "sec0005" "titulo" => "Conflict of interests" ] 1 => array:1 [ "titulo" => "References" ] ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "NotaPie" => array:1 [ 0 => array:2 [ "etiqueta" => "☆" "nota" => "<p class="elsevierStyleNotepara" id="npar0005">Please cite this article as: Yamamoto M, Yamamoto T. Lupus eritematoso discoide en una paciente con alopecia totalis. Actas Dermosifiliogr. 2021;112:77–79.</p>" ] ] "multimedia" => array:1 [ 0 => array:8 [ "identificador" => "fig0005" "etiqueta" => "Figure 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 943 "Ancho" => 1255 "Tamanyo" => 210242 ] ] "detalles" => array:1 [ 0 => array:3 [ "identificador" => "at0005" "detalle" => "Figure " "rol" => "short" ] ] "descripcion" => array:1 [ "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">(a) Alopecia totalis on the scalp and erythema scattered on the cheek, nose, and lips. (b) Infiltrative erythemas on the upper cheek. (c) A biopsy specimen showing epidermal atrophy, liquefaction of the basement membrane, dyskeratotic epidermal cells, and focal mononuclear cell infiltration in the dermis.</p>" ] ] ] "bibliografia" => array:2 [ "titulo" => "References" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:7 [ 0 => array:3 [ "identificador" => "bib0005" "etiqueta" => "1" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Incidence of alopecia areata in lupus erythematosus" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "V.P. Werth" 1 => "W.L. White" 2 => "M.R. Sanchez" 3 => "A.G. Franks" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Arch Dermatol." "fecha" => "1992" "volumen" => "128" "paginaInicial" => "368" "paginaFinal" => "371" ] ] ] ] ] ] 1 => array:3 [ "identificador" => "bib0010" "etiqueta" => "2" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Comorbidity profiles among patients with alopecia areata: the importance of onset age, a nationwide population-based study" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "S.Y. Chu" 1 => "Y.J. Chen" 2 => "W.C. Tseng" 3 => "M.W. Lin" 4 => "T.J. Chen" 5 => "C.Y. Hwang" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/j.jaad.2010.08.032" "Revista" => array:6 [ "tituloSerie" => "J Am Acad Dermatol." "fecha" => "2011" "volumen" => "65" "paginaInicial" => "949" "paginaFinal" => "956" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/21616562" "web" => "Medline" ] ] ] ] ] ] ] ] 2 => array:3 [ "identificador" => "bib0015" "etiqueta" => "3" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Alopecia areata and discoid lupus erythematosus in a patient with vitiligo" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "K. Pavithran" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Indian J Dermatol Venereol Leprol." "fecha" => "1986" "volumen" => "52" "paginaInicial" => "115" "paginaFinal" => "116" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/28150673" "web" => "Medline" ] ] ] ] ] ] ] ] 3 => array:3 [ "identificador" => "bib0020" "etiqueta" => "4" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Discoid lupus erythematosus exacerbated by contact dermatitis caused by use of squaric acid dibutylester for topical immunotherapy in a patient with alopecia areata" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "Y. Shimaoka" 1 => "A. Hatamochi" 2 => "Y. Hamasaki" 3 => "H. Suzuki" 4 => "H. Ikeda" 5 => "S. Yamazaki" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1111/j.1346-8138.2008.00435.x" "Revista" => array:6 [ "tituloSerie" => "J Dermatol." "fecha" => "2008" "volumen" => "35" "paginaInicial" => "151" "paginaFinal" => "153" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/18346258" "web" => "Medline" ] ] ] ] ] ] ] ] 4 => array:3 [ "identificador" => "bib0025" "etiqueta" => "5" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Alopecia areata totalis and universalis: a multicenter review of 132 patients in Spain" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "S. Vañó-Galván" 1 => "P. Fernández-Crehuet" 2 => "R. Grimalt" 3 => "M.J. Garcia-Hernandez" 4 => "R. Rodrigues-Barata" 5 => "S. Arias-Santiago" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1111/jdv.13959" "Revista" => array:6 [ "tituloSerie" => "J Eur Acad Dermatol Venereol." "fecha" => "2017" "volumen" => "31" "paginaInicial" => "550" "paginaFinal" => "556" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/27608049" "web" => "Medline" ] ] ] ] ] ] ] ] 5 => array:3 [ "identificador" => "bib0030" "etiqueta" => "6" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The many faces of interleukin-17 in inflammatory skin diseases" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "R. Speeckaert" 1 => "J. Lambert" 2 => "L. Grine" 3 => "M. Van Gele" 4 => "S. De Schepper" 5 => "N. van Geel" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1111/bjd.14703" "Revista" => array:6 [ "tituloSerie" => "Br J Dermatol." "fecha" => "2016" "volumen" => "175" "paginaInicial" => "892" "paginaFinal" => "901" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/27117954" "web" => "Medline" ] ] ] ] ] ] ] ] 6 => array:3 [ "identificador" => "bib0035" "etiqueta" => "7" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Dominant Th1 and minimal Th17 skewing in discoid lupus revealed by transcriptomic comparison with psoriasis" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "A. Jabbari" 1 => "M. Suárez-Fariñas" 2 => "J. Fuentes-Duculan" 3 => "J. Gonzalez" 4 => "I. Cueto" 5 => "A.G. Franks Jr" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1038/jid.2013.269" "Revista" => array:6 [ "tituloSerie" => "J Invest Dermatol." "fecha" => "2014" "volumen" => "134" "paginaInicial" => "87" "paginaFinal" => "95" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/23771123" "web" => "Medline" ] ] ] ] ] ] ] ] ] ] ] ] ] "idiomaDefecto" => "en" "url" => "/15782190/0000011200000001/v1_202101161046/S1578219020304224/v1_202101161046/en/main.assets" "Apartado" => array:4 [ "identificador" => "6157" "tipo" => "SECCION" "en" => array:2 [ "titulo" => "Case and Research Letters" "idiomaDefecto" => true ] "idiomaDefecto" => "en" ] "PDF" => "https://static.elsevier.es/multimedia/15782190/0000011200000001/v1_202101161046/S1578219020304224/v1_202101161046/en/main.pdf?idApp=UINPBA000044&text.app=https://actasdermo.org/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219020304224?idApp=UINPBA000044" ]
año/Mes | Html | Total | |
---|---|---|---|
2024 Octubre | 62 | 31 | 93 |
2024 Septiembre | 106 | 50 | 156 |
2024 Agosto | 121 | 61 | 182 |
2024 Julio | 109 | 29 | 138 |
2024 Junio | 101 | 40 | 141 |
2024 Mayo | 79 | 46 | 125 |
2024 Abril | 80 | 28 | 108 |
2024 Marzo | 92 | 43 | 135 |
2024 Febrero | 96 | 31 | 127 |
2024 Enero | 93 | 31 | 124 |
2023 Diciembre | 85 | 21 | 106 |
2023 Noviembre | 95 | 26 | 121 |
2023 Octubre | 80 | 26 | 106 |
2023 Septiembre | 74 | 42 | 116 |
2023 Agosto | 78 | 20 | 98 |
2023 Julio | 99 | 37 | 136 |
2023 Junio | 118 | 30 | 148 |
2023 Mayo | 84 | 24 | 108 |
2023 Abril | 88 | 26 | 114 |
2023 Marzo | 77 | 42 | 119 |
2023 Febrero | 54 | 33 | 87 |
2023 Enero | 60 | 60 | 120 |
2022 Diciembre | 62 | 48 | 110 |
2022 Noviembre | 41 | 21 | 62 |
2022 Octubre | 31 | 19 | 50 |
2022 Septiembre | 45 | 35 | 80 |
2022 Agosto | 34 | 45 | 79 |
2022 Julio | 21 | 62 | 83 |
2022 Junio | 24 | 31 | 55 |
2022 Mayo | 50 | 43 | 93 |
2022 Abril | 99 | 42 | 141 |
2022 Marzo | 94 | 69 | 163 |
2022 Febrero | 85 | 42 | 127 |
2022 Enero | 85 | 55 | 140 |
2021 Diciembre | 65 | 52 | 117 |
2021 Noviembre | 76 | 57 | 133 |
2021 Octubre | 76 | 79 | 155 |
2021 Septiembre | 82 | 63 | 145 |
2021 Agosto | 111 | 59 | 170 |
2021 Julio | 87 | 41 | 128 |
2021 Junio | 61 | 54 | 115 |
2021 Mayo | 65 | 52 | 117 |
2021 Abril | 198 | 131 | 329 |
2021 Marzo | 127 | 67 | 194 |
2021 Febrero | 86 | 72 | 158 |
2021 Enero | 68 | 34 | 102 |
2020 Diciembre | 7 | 3 | 10 |