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also known as storiform collagenoma&#44; is an uncommon benign tumor&#46; It clinically manifests as a firm&#44; solitary&#44; well-circumscribed&#44; whitish or flesh-colored papule or nodule and typically affects young adults&#46;<a class="elsevierStyleCrossRef" href="#bib0005"><span class="elsevierStyleSup">1</span></a> It is preferentially located on the face and extremities&#44; but has also been described on the trunk&#44; scalp&#44; oral mucosa&#44; and nail bed&#46;<a class="elsevierStyleCrossRef" href="#bib0010"><span class="elsevierStyleSup">2</span></a> Multiple SFs are considered to be a cutaneous marker of Cowden syndrome&#44;<a class="elsevierStyleCrossRef" href="#bib0005"><span class="elsevierStyleSup">1</span></a> unlike solitary lesions&#44; which are not usually observed in this hereditary skin condition&#46; Histopathologic examination shows a well-circumscribed&#44; nonencapsulated&#44; dermal tumor composed of thick hypocellular hyalinized collagen bands separated by numerous clefts and scarce fibroblasts interspersed among the collagen bands&#46; The clefts are randomly arranged and form a storiform pattern at low magnification&#46;<a class="elsevierStyleCrossRef" href="#bib0005"><span class="elsevierStyleSup">1</span></a></p><p id="par0020" class="elsevierStylePara elsevierViewall">Two theories have been proposed to explain the etiology and pathogenesis of SF&#46; According to the first theory&#44; SF is a distinct clinical and pathologic entity&#44; which in particular would explain its association with Cowden syndrome&#46; According to the second theory&#44; it would be the end stage of existing lesions&#44; such as dermatofibromas&#44; neurofibromas&#44; angiofibromas&#44; folliculitis&#44; erythema elevatum diutinum&#44; lipomas&#44; fibroma of the tendon sheath&#44; melanocytic nevi&#44; and giant cell collagenomas&#46; The most commonly associated entity is dermatofibroma&#46;<a class="elsevierStyleCrossRefs" href="#bib0015"><span class="elsevierStyleSup">3&#44;4</span></a></p><p id="par0025" class="elsevierStylePara elsevierViewall">A recent dermoscopic study of SF&#44; the first of its kind&#44; described a homogeneous lesion against a white background with peripheral arborizing vessels and a perilesional erythematous halo&#46;<a class="elsevierStyleCrossRef" href="#bib0010"><span class="elsevierStyleSup">2</span></a> Our findings were very similar&#46; The following conditions should be contemplated in the differential diagnosis&#58; atypical dermatofibroma&#44; late-stage sclerotic dermatofibroma&#44; basal cell carcinoma&#44; hypomelanotic or amelanotic blue nevus&#44; and amelanotic melanoma&#46;<a class="elsevierStyleCrossRef" href="#bib0010"><span class="elsevierStyleSup">2</span></a> Unlike SF&#44; atypical and late-stage sclerotic dermatofibromas usually have a delicate peripheral pigment network&#46;<a class="elsevierStyleCrossRef" href="#bib0025"><span class="elsevierStyleSup">5</span></a> Additional dermoscopic features observed in basal cell carcinoma include cartwheel structures&#44; maple leaf&#8211;like areas&#44; ulceration&#44; multiple globules&#44; and blue-gray ovoid nests&#46; Blue nevus and amelanotic melanoma do not always exhibit a residual blue-brownish pigment&#44;<a class="elsevierStyleCrossRef" href="#bib0030"><span class="elsevierStyleSup">6</span></a> making them more difficult to distinguish from SF&#46;</p><p id="par0030" class="elsevierStylePara elsevierViewall">We have presented a new case of SF with very similar dermoscopic findings to those recently described&#46; Although dermoscopy can provide important diagnostic clues&#44; a diagnosis of SF must be histologically confirmed&#46;</p></span><span id="sec0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0015">Conflicts of Interest</span><p id="par0035" class="elsevierStylePara elsevierViewall">The authors declare that they have no conflicts of interest&#46;</p></span></span>"
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Practical Dermoscopy
Solitary Sclerotic Fibroma: Dermoscopic Features
Fibroma esclerótico solitario: características dermatoscópicas
N. Setó-Torrenta,
Autor para correspondencia
nurisetorrent@gmail.com

Corresponding author.
, G. Melé-Ninota, M. Quintana-Codinaa, R. Ballester-Victoriab
a Servicio de Dermatología, Hospital Universitari Sagrat Cor, Barcelona, Spain
b Servicio de Anatomía Patológica, Hospital Universitari Sagrat Cor, Barcelona, Spain
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also known as storiform collagenoma&#44; is an uncommon benign tumor&#46; It clinically manifests as a firm&#44; solitary&#44; well-circumscribed&#44; whitish or flesh-colored papule or nodule and typically affects young adults&#46;<a class="elsevierStyleCrossRef" href="#bib0005"><span class="elsevierStyleSup">1</span></a> It is preferentially located on the face and extremities&#44; but has also been described on the trunk&#44; scalp&#44; oral mucosa&#44; and nail bed&#46;<a class="elsevierStyleCrossRef" href="#bib0010"><span class="elsevierStyleSup">2</span></a> Multiple SFs are considered to be a cutaneous marker of Cowden syndrome&#44;<a class="elsevierStyleCrossRef" href="#bib0005"><span class="elsevierStyleSup">1</span></a> unlike solitary lesions&#44; which are not usually observed in this hereditary skin condition&#46; Histopathologic examination shows a well-circumscribed&#44; nonencapsulated&#44; dermal tumor composed of thick hypocellular hyalinized collagen bands separated by numerous clefts and scarce fibroblasts interspersed among the collagen bands&#46; The clefts are randomly arranged and form a storiform pattern at low magnification&#46;<a class="elsevierStyleCrossRef" href="#bib0005"><span class="elsevierStyleSup">1</span></a></p><p id="par0020" class="elsevierStylePara elsevierViewall">Two theories have been proposed to explain the etiology and pathogenesis of SF&#46; According to the first theory&#44; SF is a distinct clinical and pathologic entity&#44; which in particular would explain its association with Cowden syndrome&#46; According to the second theory&#44; it would be the end stage of existing lesions&#44; such as dermatofibromas&#44; neurofibromas&#44; angiofibromas&#44; folliculitis&#44; erythema elevatum diutinum&#44; lipomas&#44; fibroma of the tendon sheath&#44; melanocytic nevi&#44; and giant cell collagenomas&#46; The most commonly associated entity is dermatofibroma&#46;<a class="elsevierStyleCrossRefs" href="#bib0015"><span class="elsevierStyleSup">3&#44;4</span></a></p><p id="par0025" class="elsevierStylePara elsevierViewall">A recent dermoscopic study of SF&#44; the first of its kind&#44; described a homogeneous lesion against a white background with peripheral arborizing vessels and a perilesional erythematous halo&#46;<a class="elsevierStyleCrossRef" href="#bib0010"><span class="elsevierStyleSup">2</span></a> Our findings were very similar&#46; The following conditions should be contemplated in the differential diagnosis&#58; atypical dermatofibroma&#44; late-stage sclerotic dermatofibroma&#44; basal cell carcinoma&#44; hypomelanotic or amelanotic blue nevus&#44; and amelanotic melanoma&#46;<a class="elsevierStyleCrossRef" href="#bib0010"><span class="elsevierStyleSup">2</span></a> Unlike SF&#44; atypical and late-stage sclerotic dermatofibromas usually have a delicate peripheral pigment network&#46;<a class="elsevierStyleCrossRef" href="#bib0025"><span class="elsevierStyleSup">5</span></a> Additional dermoscopic features observed in basal cell carcinoma include cartwheel structures&#44; maple leaf&#8211;like areas&#44; ulceration&#44; multiple globules&#44; and blue-gray ovoid nests&#46; Blue nevus and amelanotic melanoma do not always exhibit a residual blue-brownish pigment&#44;<a class="elsevierStyleCrossRef" href="#bib0030"><span class="elsevierStyleSup">6</span></a> making them more difficult to distinguish from SF&#46;</p><p id="par0030" class="elsevierStylePara elsevierViewall">We have presented a new case of SF with very similar dermoscopic findings to those recently described&#46; Although dermoscopy can provide important diagnostic clues&#44; a diagnosis of SF must be histologically confirmed&#46;</p></span><span id="sec0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0015">Conflicts of Interest</span><p id="par0035" class="elsevierStylePara elsevierViewall">The authors declare that they have no conflicts of interest&#46;</p></span></span>"
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2023 Abril 152 32 184
2023 Marzo 162 40 202
2023 Febrero 150 27 177
2023 Enero 131 44 175
2022 Diciembre 114 50 164
2022 Noviembre 83 30 113
2022 Octubre 73 54 127
2022 Septiembre 80 55 135
2022 Agosto 96 33 129
2022 Julio 70 42 112
2022 Junio 52 27 79
2022 Mayo 149 39 188
2022 Abril 179 33 212
2022 Marzo 168 65 233
2022 Febrero 142 25 167
2022 Enero 171 42 213
2021 Diciembre 154 51 205
2021 Noviembre 146 44 190
2021 Octubre 141 56 197
2021 Septiembre 127 45 172
2021 Agosto 100 41 141
2021 Julio 90 34 124
2021 Junio 118 26 144
2021 Mayo 124 42 166
2021 Abril 288 117 405
2021 Marzo 151 45 196
2021 Febrero 81 38 119
2021 Enero 80 23 103
2020 Diciembre 67 25 92
2020 Noviembre 21 17 38
2020 Octubre 16 9 25
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¿Es usted profesional sanitario apto para prescribir o dispensar medicamentos?

Are you a health professional able to prescribe or dispense drugs?