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    "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">The use of fillers for esthetic purposes has increased in recent years&#46; Complications secondary to the use of permanent and nonpermanent fillers have been widely described&#46;<a class="elsevierStyleCrossRef" href="#bib0040"><span class="elsevierStyleSup">1</span></a> However&#44; the literature on complications in men is scarce&#46; Here&#44; we describe the clinical and epidemiological characteristics of men with adverse reactions to fillers&#46;</p><p id="par0010" class="elsevierStylePara elsevierViewall">We carried out a retrospective study of men with adverse reactions to fillers who visited the dermatology department of the Hospital Cl&#237;nic de Barcelona between May 1&#44; 2015&#44; and October 31&#44; 2018&#46; Corresponding medical records&#44; photographs&#44; and additional tests were reviewed&#46; Ultrasound evaluation was performed using an Esaote Mylab ClassC kit with 18-MHz and 22-MHz probes&#46;</p><p id="par0015" class="elsevierStylePara elsevierViewall">Our analysis included 6 men &#40;one of whom was the subject of a previous publication<a class="elsevierStyleCrossRef" href="#bib0045"><span class="elsevierStyleSup">2</span></a>&#41;&#58; 1 was transsexual&#59; 3 were men who have sex with men &#40;MSM&#41;&#59; and 2 were heterosexual &#40;<a class="elsevierStyleCrossRef" href="#tbl0005">Table 1</a>&#41;&#46; Three of the patients had human immunodeficiency virus &#40;HIV&#41;&#46; All had been referred from another service with different diagnoses&#46; Adverse reactions to fillers were never suspected&#46; The most frequent filler injection site was the buttocks &#40;4 patients&#41;&#44; followed by the face &#40;2 patients&#41;&#46; The patients reported receiving injections of hyaluronic acid &#40;1 patient&#41;&#44; liquid silicone &#40;2 patients&#41;&#44; petrolatum &#40;1 patient&#41;&#44; polyalkylimide &#40;1 patient&#41;&#44; and an unknown agent &#40;1 patient&#41;&#46; Two of the 6 patients initially denied having undergone dermal filling&#46; The time from infiltration to adverse reaction ranged from 2 to 15 years&#46; The most frequent clinical presentations were recurrent pseudocellulitis &#40;4 patients&#41;&#44; filler migration &#40;3 patients&#41;&#44; nodule formation &#40;2 patients&#41;&#44; and knee pain &#40;1 patient&#41;&#46; Two of the patients had undergone computed axial tomography &#40;CAT&#41;&#44; which revealed signs of myositis and cellulitis &#40;patients 2 and 5&#41;&#44; but not the presence of filling agent&#46; High frequency ultrasound &#40;HIFU&#41; revealed findings compatible with adverse reaction to filler in all cases&#46; In 1 patient who was unaware of the type of filler used&#44; HIFU revealed a snowstorm-like pattern characteristic of liquid silicone &#40;<a class="elsevierStyleCrossRef" href="#fig0005">Fig&#46; 1</a>&#41;&#46; In another individual who reported having received hyaluronic acid infiltrations&#44; HIFU revealed characteristics compatible with petrolatum &#40;anechoic pseudocysts&#41; &#40;<a class="elsevierStyleCrossRef" href="#fig0010">Fig&#46; 2</a>&#41;&#46; In 1 case&#44; treatment consisted of removal of the filler&#46; Three patients were treated with oral corticosteroids&#44; 2 with minocycline&#44; and 2 with nonsteroidal anti-inflammatory drugs&#46; One patient was lost to follow-up&#46; The clinical response was variable &#40;<a class="elsevierStyleCrossRef" href="#tbl0005">Table 1</a>&#41;&#46;</p><elsevierMultimedia ident="tbl0005"></elsevierMultimedia><elsevierMultimedia ident="fig0005"></elsevierMultimedia><elsevierMultimedia ident="fig0010"></elsevierMultimedia><p id="par0020" class="elsevierStylePara elsevierViewall">Adverse reactions to fillers can cause severe morbidity with foreign body granulomatous reactions&#44; pseudocellulitis&#44; skin necrosis&#44; embolization and migration of filler material&#44; and even death&#46;<a class="elsevierStyleCrossRefs" href="#bib0040"><span class="elsevierStyleSup">1&#44;3</span></a> In our series&#44; the most common complications were pseudocellulitis and filler migration&#46;</p><p id="par0025" class="elsevierStylePara elsevierViewall">It should be noted that all patients were referred from other services and in no case was adverse reaction to filler suspected&#44; likely due to the great variability in clinical presentation&#44; the long latency to symptom onset &#40;up to 15 years in our series&#41;&#44; a reluctance to admit having undergone the procedure &#40;or failure to recall the procedure in cases in which many years had elapsed&#41;&#44; and a lack of suspicion of this condition in men&#46; The misdiagnosis of recurrent cellulitis or myositis led in several cases to costly imaging tests and multiple cycles of broad-spectrum antibiotic therapy&#44; with potential associated adverse effects&#46;</p><p id="par0030" class="elsevierStylePara elsevierViewall">Some authors have suggested that the use of unauthorized fillers such as liquid silicone and petrolatum is increasing among transsexuals and bodybuilders&#46;<a class="elsevierStyleCrossRefs" href="#bib0050"><span class="elsevierStyleSup">3&#44;4</span></a> In our series&#44; most of the fillers used corresponded to this group &#40;silicone and petrolatum in 3 and 2 cases&#44; respectively&#41;&#46; However&#44; only 1 of the individuals was transsexual&#44; none were bodybuilders&#44; and 2 were heterosexual&#44; underscoring the need for a high index of clinical suspicion when evaluating men with inflammatory dermatoses&#44; especially on the face&#44; buttocks&#44; and thighs&#46;</p><p id="par0035" class="elsevierStylePara elsevierViewall">HIFU is a fast&#44; inexpensive&#44; and safe test&#46; It is useful in the diagnosis of adverse reaction to filler to assess the magnitude of the inflammatory reaction&#44; identify the type of filling agent used&#44; monitor the response to treatment&#44; and guide procedures&#46;<a class="elsevierStyleCrossRefs" href="#bib0060"><span class="elsevierStyleSup">5&#8211;7</span></a> In our series&#44; HIFU revealed the presence of fillers in all cases&#44; even in 2 patients in whom CAT failed to do so&#46;</p><p id="par0040" class="elsevierStylePara elsevierViewall">The only curative treatment for adverse reaction to filler is extraction of the filling agent&#44;<a class="elsevierStyleCrossRef" href="#bib0055"><span class="elsevierStyleSup">4</span></a> which can be difficult&#59; this was achieved in only 1 patient in our series&#46; Variable responses have been described in patients treated with oral and intralesional corticosteroid therapy&#44; tacrolimus&#44; allopurinol&#44; etanercept&#44; and antibiotics such as clarithromycin and tetracyclines&#46;<a class="elsevierStyleCrossRefs" href="#bib0040"><span class="elsevierStyleSup">1&#44;3</span></a> Most patients in our series received oral corticosteroids&#44; and 1 patient &#40;patient 2&#41; required low doses of prednisone for more than 12 months&#46;</p><p id="par0045" class="elsevierStylePara elsevierViewall">Adverse reaction to filler in men can occur more than a decade after the procedure&#44; can have varied clinical presentations&#44; and is not limited to MSM or transsexuals&#46; It should be suspected in individuals with inflammatory conditions affecting the face&#44; thighs&#44; or buttocks&#44; even in those who deny having undergone dermal filling&#46;</p><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0005">Conflicts of Interest</span><p id="par0050" class="elsevierStylePara elsevierViewall">The authors declare that they have no conflicts of interest&#46;</p></span></span>"
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        "nota" => "<p class="elsevierStyleNotepara" id="npar0015">Please cite this article as&#58; Morgado-Carrasco D&#44; Bosch-Amate X&#44; Fust&#224;-Novell X&#44; Giavedoni P&#46; Complicaciones de rellenos &#40;<span class="elsevierStyleItalic">fillers</span>&#41; en hombres&#46; Estudio retrospectivo de las caracter&#237;sticas epidemiol&#243;gicas y cl&#237;nicas&#46; Utilidad de la ecograf&#237;a en el diagn&#243;stico&#46; Actas Dermosifiliogr&#46; 2020&#59;111&#58;429&#8211;432&#46;</p>"
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          "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">A&#44; Significant increase in volume on the dorsal aspect of both feet of patient 1&#46; B&#44; Color Doppler ultrasound &#40;18-MHz probe&#41; in patient 1 reveals a small anechoic pseudocyst with posterior reinforcement&#44; no increase in vascularization&#44; and a snowstorm-like pattern&#46;</p>"
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          "en" => "<p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">A&#44; Erythematous edematous plaque on the left thigh of patient 5&#46; B&#44; Numerous hypoechoic or anechoic pseudocysts in subcutaneous tissue in patient 5 &#40;B-mode ultrasound with 18-MHz probe&#41;&#46; C&#44; Increased vascularization in patient 5 &#40;color Doppler ultrasound with 18-MHz probe&#41;&#46;</p>"
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          "leyenda" => "<p id="spar0020" class="elsevierStyleSimplePara elsevierViewall"><span class="elsevierStyleItalic">Abbreviations</span>&#58; HIV&#44; human immunodeficiency virus&#59; F&#44; female&#59; IgM&#44; immunoglobulin M&#59; M&#44; man&#59; M2F&#44; male-to-female transition&#59; MSM&#44; men who have sex with men&#59; N&#47;A&#44; not applicable&#59; NSAIDs&#44; nonsteroidal anti-inflammatory drugs&#59; ST&#44; subcutaneous tissue&#46;</p>"
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                0 => """
                  <table border="0" frame="\n
                  \t\t\t\t\tvoid\n
                  \t\t\t\t" class=""><thead title="thead"><tr title="table-row"><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">Patient&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">Age&#44; y&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">Gender Identity&#47;Sexual Orientation&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">Comorbidities&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">Type of Filler&#47;Infiltration Site&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">Adverse Effect &#40;Time Since Infiltration&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">Dermal Filling Denied by Patient&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">High Frequency Ultrasound&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">Referral Diagnosis&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">Treatment&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">Response to Treatment&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th></tr></thead><tbody title="tbody"><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">1&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">27&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">F &#40;M2F&#41;&#47;unknown&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">HIV&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Liquid silicone&#47;buttocks&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Migration to feet and secondary lymphedema &#40;3<span class="elsevierStyleHsp" style=""></span>y&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">No&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Snowstorm pattern&#46; Small anechoic pseudocysts&#46; No increase in vascularity&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Lymphedema&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">None&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">N&#47;A&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">2&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">28&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">M&#47;heterosexual&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">No&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Petrolatum&#47;buttocks&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Repeated pseudocellulitis in buttocks and sacrum &#40;2<span class="elsevierStyleHsp" style=""></span>y&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Yes&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Pseudocysts in ST and muscle&#46; Increased vascularity&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Recurrent cellulitis&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">HydroxychloroquineAllopurinolMinocyclineOral prednisone&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Only responded to prolonged oral prednisone therapy&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">3&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">69&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">M&#47;heterosexual&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">HypertensionIgM monoclonal gammopathy&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Liquid silicone&#44; unknown&#47;face<a class="elsevierStyleCrossRef" href="#tblfn0005">&#42;</a>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Erythematous nodules&#44; edema&#44; and limited buccal mobility &#40;12<span class="elsevierStyleHsp" style=""></span>y&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Yes&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Snowstorm pattern&#46; Increased vascularity&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Autoinflammatory syndrome &#40;Schnitzler syndrome&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">MinocyclineOral prednisone&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Good response to prednisone&#44; then discontinued treatment&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">4&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">39&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">M&#47;MSM&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">HIV&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Polyalkylimide&#47;face&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Erythematous nodules on both cheeks &#40;5<span class="elsevierStyleHsp" style=""></span>y&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">No&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Pseudocyst beneath the muscle&#46; Increased vascularity&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Rosacea&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Filler removal&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Good response&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">5&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">38&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
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                  \t\t\t\t\ttable-entry\n
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                  \t\t\t\t">No&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><a class="elsevierStyleCrossRef" href="#tblfn0010">&#42;&#42;</a>Hyaluronic acid&#44; petrolatum&#47;buttocks&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">Pseudocellulitis on the right thigh&#44; myositis &#40;12<span class="elsevierStyleHsp" style=""></span>y&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-entry\n
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                  \t\t\t\t">Pseudocysts in ST and muscle&#46; Increased vascularity&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttop\n
                  \t\t\t\t">Myositis&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">Oral prednisoneNSAIDs &#40;dexketoprofen&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">6&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">39&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">M&#47;MSM&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">HIV&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Liquid silicone&#47;buttocks&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
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                  \t\t\t\t">Knee pain&#44; nodules on thighs&#44; pseudocellulitis &#40;15<span class="elsevierStyleHsp" style=""></span>y&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">No&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Snowstorm pattern&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-entry\n
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                  \t\t\t\t\ttop\n
                  \t\t\t\t">Fasciitis&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Partial response&#44; nodules and discomfort persisted&nbsp;\t\t\t\t\t\t\n
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            0 => array:3 [
              "identificador" => "bib0040"
              "etiqueta" => "1"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Materiales de relleno&#58; tipos&#44; indicaciones y complicaciones"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "I&#46; S&#225;nchez-Carpintero"
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                            2 => "R&#46; Ruiz-Rodr&#237;guez"
                          ]
                        ]
                      ]
                    ]
                  ]
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                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Actas Dermo-Sifiliogr"
                        "fecha" => "2010"
                        "volumen" => "101"
                        "paginaInicial" => "381"
                        "paginaFinal" => "393"
                      ]
                    ]
                  ]
                ]
              ]
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            1 => array:3 [
              "identificador" => "bib0045"
              "etiqueta" => "2"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Linfedema en ambos pies secundario a migraci&#243;n de silicona l&#237;quida"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "D&#46; Morgado-Carrasco"
                            1 => "A&#46; Combalia"
                            2 => "E&#46; Rodr&#237;guez-Lobato"
                            3 => "X&#46; Fust&#224;-Novell"
                            4 => "L&#46; Al&#243;s-Hernandez"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Piel"
                        "fecha" => "2017"
                        "volumen" => "32"
                        "paginaInicial" => "540"
                        "paginaFinal" => "542"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            2 => array:3 [
              "identificador" => "bib0050"
              "etiqueta" => "3"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Nonmedical-grade injections of permanent fillers&#58; medical and medicolegal considerations"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "A&#46; Styperek"
                            1 => "S&#46; Bayers"
                            2 => "M&#46; Beer"
                            3 => "K&#46; Beer"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "J Clin Aesthetic Dermatol"
                        "fecha" => "2013"
                        "volumen" => "6"
                        "paginaInicial" => "22"
                        "paginaFinal" => "29"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            3 => array:3 [
              "identificador" => "bib0055"
              "etiqueta" => "4"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Complications in self-injection of chemicals to increase muscle"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "F&#46;F&#46; Laitano"
                            1 => "A&#46; Gazzale"
                            2 => "E&#46;J&#46; Siqueira"
                            3 => "P&#46;D&#46;E&#46; Martins"
                            4 => "M&#46;P&#46; Oliveira"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Rev Bras Cir Pl&#225;st"
                        "fecha" => "2016"
                        "volumen" => "31"
                        "paginaInicial" => "136"
                        "paginaFinal" => "139"
                      ]
                    ]
                  ]
                ]
              ]
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              "identificador" => "bib0060"
              "etiqueta" => "5"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Sonographic outcomes of cosmetic procedures"
                      "autores" => array:1 [
                        0 => array:2 [
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                          "autores" => array:2 [
                            0 => "X&#46; Wortsman"
                            1 => "J&#46; Wortsman"
                          ]
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                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Am J Roentgenol"
                        "fecha" => "2011"
                        "volumen" => "197"
                        "paginaInicial" => "W910"
                        "paginaFinal" => "W918"
                      ]
                    ]
                  ]
                ]
              ]
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              "identificador" => "bib0065"
              "etiqueta" => "6"
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                    0 => array:2 [
                      "titulo" => "Ecograf&#237;a de los materiales de relleno inyectables y su inter&#233;s en el seguimiento diagn&#243;stico"
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                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "F&#46;M&#46; De Cabo-Franc&#233;s"
                            1 => "J&#46;M&#46; Alcolea"
                            2 => "I&#46; Bov&#233;-Farr&#233;"
                            3 => "C&#46; Pedret"
                            4 => "M&#46;A&#46; Trelles"
                          ]
                        ]
                      ]
                    ]
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                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Cir Pl&#225;stica Ibero-Latinoam"
                        "fecha" => "2012"
                        "volumen" => "38"
                        "paginaInicial" => "179"
                        "paginaFinal" => "187"
                      ]
                    ]
                  ]
                ]
              ]
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              "identificador" => "bib0070"
              "etiqueta" => "7"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Parafinoma de pene&#58; &#191;le hacemos una ecograf&#237;a&#63;"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "C&#46; Morales-Raya"
                            1 => "A&#46; Calleja-Algarra"
                            2 => "F&#46; Tous-Romero"
                            3 => "R&#46; Rivera-D&#237;az"
                          ]
                        ]
                      ]
                    ]
                  ]
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                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Actas Dermo-Sifiliogr"
                        "fecha" => "2017"
                        "volumen" => "108"
                        "paginaInicial" => "478"
                        "paginaFinal" => "480"
                      ]
                    ]
                  ]
                ]
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