Estadísticas

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    "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">The authors present the results of a Delphi study conducted in Spain on the use of apremilast in psoriasis&#46;<a class="elsevierStyleCrossRef" href="#bib0005"><span class="elsevierStyleSup">1</span></a> Apremilast is a &#8220;small-molecule&#8221; oral phosphodiesterase 4 inhibitor that according to its summary of product characteristics is indicated for the treatment of psoriatic arthritis and chronic moderate to severe plaque psoriasis&#46; The position of apremilast in the current arsenal of treatments for psoriasis has been influenced by several factors&#46; First&#44; its limited effectiveness compared with other alternatives&#59; second its adverse effects&#44; which in many cases require withdrawal of treatment due to poor tolerability&#59; and last but not least&#44; its cost&#44; which is similar to that of the most effective biologic drugs available and higher than that of other biosimilars&#46;</p><p id="par0010" class="elsevierStylePara elsevierViewall">The authors&#44; all experts in psoriasis&#44; chose 5 points of interest to analyze using a Delphi questionnaire&#46; After reviewing each point based on the existing literature&#44; the panel concluded that apremilast might be a treatment option for patients with a different profile to that studied in the clinical trials&#46; They highlight the need for a consensus-based definition of moderate psoriasis&#44; which is where apremilast could possibly be positioned as a treatment option preceding biologic therapy&#46; Finally&#44; they stress the need for more scientific evidence from clinical trials and real-world studies to verify the opinions expressed in this study&#46;</p></span>"
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