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Commentaries
Leadership in the Treatment of Skin Cancer
El liderazgo en el tratamiento del cáncer cutáneo
A. Boada
Servicio de Dermatología, Hospital Universitari Germans Trias i Pujol, Institut Germans Trias i Pujol, Universitat Autònoma de Barcelona, Badalona, Barcelona, Spain
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            "entidad" => "Servicio de Dermatolog&#237;a&#44; Hospital Universitari Germans Trias i Pujol&#44; Institut Germans Trias i Pujol&#44; Universitat Aut&#242;noma de Barcelona&#44; Badalona&#44; Barcelona&#44; Spain"
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      ]
    ]
    "titulosAlternativos" => array:1 [
      "es" => array:1 [
        "titulo" => "El liderazgo en el tratamiento del c&#225;ncer cut&#225;neo"
      ]
    ]
    "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">In recent years&#44; we have seen the introduction of several new therapies for metastatic skin cancer that have had a marked impact on the survival of our patients&#46; These results have been accompanied by a growing interest in medical oncology for patients with skin cancer&#46; This could increase further with the use of these drugs as adjuvant therapies&#44; that is&#44; for the treatment of patients who are at high risk but currently disease-free&#46;</p><p id="par0010" class="elsevierStylePara elsevierViewall">If dermatologists are to retain their leadership role in the management of skin cancer&#44; they will have to acquire the tools they need to continue fulfilling this role&#46; In this context&#44; we applaud the AEDV&#39;s initiative in publishing Clinical Practice Guidelines &#40;CPG&#41; for the management of the main skin cancers&#46; These guidelines review the available evidence in order to resolve the dilemmas that arise in the management of certain situations&#46; They also include recommendations specifically adapted to the Spanish setting&#46; This issue includes CPG on the diagnosis and treatment of Merkel cell carcinoma&#46;<a class="elsevierStyleCrossRef" href="#bib0020"><span class="elsevierStyleSup">1</span></a></p><p id="par0015" class="elsevierStylePara elsevierViewall">In the case of Merkel cell carcinoma&#44; CPG are particularly useful for 3 reasons&#58; a dramatic increase in the incidence of this tumor due to the growth of the population at risk &#40;as a result of aging of the population&#44; exposure to UV radiation&#44; and immunosuppression&#41;<a class="elsevierStyleCrossRef" href="#bib0025"><span class="elsevierStyleSup">2</span></a>&#59; the aggressive nature of the disease &#40;with survival at 5 years of only 45&#37; of patients diagnosed with a stage T1 tumor&#41;<a class="elsevierStyleCrossRef" href="#bib0030"><span class="elsevierStyleSup">3</span></a>&#59; and the fact that correct decisions in the initial stages of the disease can be vital in achieving a successful therapeutic outcome&#46;</p></span>"
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        "nota" => "<p class="elsevierStyleNotepara" id="npar0005">Please cite this article as&#58; Boada A&#46; El liderazgo en el tratamiento del c&#225;ncer cut&#225;neo&#46; Actas Dermosifiliogr&#46; 2019&#59;110&#58;423&#46;</p>"
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    ]
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      "titulo" => "References"
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            0 => array:3 [
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              "etiqueta" => "1"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Carcinoma de c&#233;lulas de Merkel&#58; diagn&#243;stico y tratamiento en atenci&#243;n especializada dermatol&#243;gica&#46; Gu&#237;a de Pr&#225;ctica Cl&#237;nica de la AEDV"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "J&#46; V&#225;zquez Doval"
                            1 => "B&#46; Llombart Cussac"
                            2 => "A&#46; P&#233;rez Bustillo"
                            3 => "S&#46; Paradela de la Morena"
                            4 => "M&#46;J&#46; Fuente Gonz&#225;lez"
                            5 => "M&#46;T&#46; Fern&#225;ndez-Figueras"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1016/j.ad.2019.01.006"
                      "Revista" => array:2 [
                        "tituloSerie" => "Actas dermosifiliogr"
                        "fecha" => "2019"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            1 => array:3 [
              "identificador" => "bib0025"
              "etiqueta" => "2"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Epidemiology of Merkel cell carcinoma&#46; A population-based study from 1985 to 2013&#44; in northeastern of France"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "A&#46; Kieny"
                            1 => "B&#46; Cribier"
                            2 => "N&#46; Meyer"
                            3 => "M&#46; Velten"
                            4 => "J&#46; J&#233;gu"
                            5 => "D&#46; Lipsker"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1002/ijc.31860"
                      "Revista" => array:6 [
                        "tituloSerie" => "Int J Cancer"
                        "fecha" => "2019"
                        "volumen" => "144"
                        "paginaInicial" => "741"
                        "paginaFinal" => "745"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/30194728"
                            "web" => "Medline"
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                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            2 => array:3 [
              "identificador" => "bib0030"
              "etiqueta" => "3"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Analysis of prognostic factors from 9387 Merkel cell carcinoma cases forms the basis for the new 8th edition AJCC staging system"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "K&#46;L&#46; Harms"
                            1 => "M&#46;A&#46; Healy"
                            2 => "P&#46; Nghiem"
                            3 => "A&#46;J&#46; Sober"
                            4 => "T&#46;M&#46; Johnson"
                            5 => "C&#46;K&#46; Bichakjian"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1245/s10434-016-5266-4"
                      "Revista" => array:6 [
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                        "fecha" => "2016"
                        "volumen" => "23"
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                        "paginaFinal" => "3571"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/27198511"
                            "web" => "Medline"
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Información del artículo
ISSN: 15782190
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