array:24 [
  "pii" => "S1578219019301490"
  "issn" => "15782190"
  "doi" => "10.1016/j.adengl.2019.05.002"
  "estado" => "S300"
  "fechaPublicacion" => "2019-07-01"
  "aid" => "2149"
  "copyright" => "Elsevier España, S.L.U. and AEDV"
  "copyrightAnyo" => "2019"
  "documento" => "article"
  "crossmark" => 1
  "subdocumento" => "fla"
  "cita" => "Actas Dermosifiliogr. 2019;110:474-81"
  "abierto" => array:3 [
    "ES" => true
    "ES2" => true
    "LATM" => true
  ]
  "gratuito" => true
  "lecturas" => array:2 [
    "total" => 1
    "HTML" => 1
  ]
  "Traduccion" => array:1 [
    "es" => array:19 [
      "pii" => "S0001731019300602"
      "issn" => "00017310"
      "doi" => "10.1016/j.ad.2019.01.002"
      "estado" => "S300"
      "fechaPublicacion" => "2019-07-01"
      "aid" => "2149"
      "copyright" => "AEDV"
      "documento" => "article"
      "crossmark" => 1
      "subdocumento" => "fla"
      "cita" => "Actas Dermosifiliogr. 2019;110:474-81"
      "abierto" => array:3 [
        "ES" => true
        "ES2" => true
        "LATM" => true
      ]
      "gratuito" => true
      "lecturas" => array:2 [
        "total" => 562
        "formatos" => array:2 [
          "HTML" => 368
          "PDF" => 194
        ]
      ]
      "es" => array:14 [
        "idiomaDefecto" => true
        "cabecera" => "<span class="elsevierStyleTextfn">Original</span>"
        "titulo" => "Regla &#171;1-2-3&#187; para la reconstrucci&#243;n de defectos de mediano tama&#241;o del cuero cabelludo"
        "tienePdf" => "es"
        "tieneTextoCompleto" => "es"
        "tieneResumen" => array:3 [
          0 => "es"
          1 => "es"
          2 => "en"
        ]
        "paginas" => array:1 [
          0 => array:2 [
            "paginaInicial" => "474"
            "paginaFinal" => "481"
          ]
        ]
        "titulosAlternativos" => array:1 [
          "en" => array:1 [
            "titulo" => "Reconstruction of Moderate-Sized Scalp Defects&#58; A 1-2-3 Rule"
          ]
        ]
        "contieneResumen" => array:2 [
          "es" => true
          "en" => true
        ]
        "contieneTextoCompleto" => array:1 [
          "es" => true
        ]
        "contienePdf" => array:1 [
          "es" => true
        ]
        "resumenGrafico" => array:2 [
          "original" => 1
          "multimedia" => array:5 [
            "identificador" => "fig0030"
            "tipo" => "MULTIMEDIAFIGURA"
            "mostrarFloat" => false
            "mostrarDisplay" => true
            "figura" => array:1 [
              0 => array:4 [
                "imagen" => "fx1.jpeg"
                "Alto" => 679
                "Ancho" => 1333
                "Tamanyo" => 66035
              ]
            ]
          ]
        ]
        "autores" => array:1 [
          0 => array:2 [
            "autoresLista" => "F&#46; Russo"
            "autores" => array:1 [
              0 => array:2 [
                "nombre" => "F&#46;"
                "apellidos" => "Russo"
              ]
            ]
          ]
        ]
        "resumen" => array:1 [
          0 => array:3 [
            "titulo" => "Graphical abstract"
            "clase" => "graphical"
            "resumen" => "<span id="abst0005" class="elsevierStyleSection elsevierViewall"><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall"><elsevierMultimedia ident="fig0030"></elsevierMultimedia></p></span>"
          ]
        ]
      ]
      "idiomaDefecto" => "es"
      "Traduccion" => array:1 [
        "en" => array:9 [
          "pii" => "S1578219019301490"
          "doi" => "10.1016/j.adengl.2019.05.002"
          "estado" => "S300"
          "subdocumento" => ""
          "abierto" => array:3 [
            "ES" => true
            "ES2" => true
            "LATM" => true
          ]
          "gratuito" => true
          "lecturas" => array:1 [
            "total" => 0
          ]
          "idiomaDefecto" => "en"
          "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219019301490?idApp=UINPBA000044"
        ]
      ]
      "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0001731019300602?idApp=UINPBA000044"
      "url" => "/00017310/0000011000000006/v1_201907020633/S0001731019300602/v1_201907020633/es/main.assets"
    ]
  ]
  "itemSiguiente" => array:19 [
    "pii" => "S1578219019301635"
    "issn" => "15782190"
    "doi" => "10.1016/j.adengl.2019.01.016"
    "estado" => "S300"
    "fechaPublicacion" => "2019-07-01"
    "aid" => "2152"
    "copyright" => "Elsevier Espa&#241;a&#44; S&#46;L&#46;U&#46; and AEDV"
    "documento" => "article"
    "crossmark" => 1
    "subdocumento" => "fla"
    "cita" => "Actas Dermosifiliogr. 2019;110:482-9"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:2 [
      "total" => 1
      "HTML" => 1
    ]
    "en" => array:12 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">Original Article</span>"
      "titulo" => "Complications and Sequelae After Sentinel Lymph Node Biopsy in Melanoma&#58; A Retrospective Cohort Study"
      "tienePdf" => "en"
      "tieneTextoCompleto" => "en"
      "tieneResumen" => array:2 [
        0 => "en"
        1 => "es"
      ]
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "482"
          "paginaFinal" => "489"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "es" => array:1 [
          "titulo" => "Complicaciones y secuelas de la t&#233;cnica de biopsia selectiva del ganglio centinela para el melanoma en una cohorte retrospectiva"
        ]
      ]
      "contieneResumen" => array:2 [
        "en" => true
        "es" => true
      ]
      "contieneTextoCompleto" => array:1 [
        "en" => true
      ]
      "contienePdf" => array:1 [
        "en" => true
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "C&#46;E&#46; Espinosa-Pereiro, A&#46; Zulaica G&#225;rate, I&#46; Garc&#237;a-Doval"
          "autores" => array:3 [
            0 => array:2 [
              "nombre" => "C&#46;E&#46;"
              "apellidos" => "Espinosa-Pereiro"
            ]
            1 => array:2 [
              "nombre" => "A&#46;"
              "apellidos" => "Zulaica G&#225;rate"
            ]
            2 => array:2 [
              "nombre" => "I&#46;"
              "apellidos" => "Garc&#237;a-Doval"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "en"
    "Traduccion" => array:1 [
      "es" => array:9 [
        "pii" => "S0001731019300638"
        "doi" => "10.1016/j.ad.2019.01.003"
        "estado" => "S300"
        "subdocumento" => ""
        "abierto" => array:3 [
          "ES" => true
          "ES2" => true
          "LATM" => true
        ]
        "gratuito" => true
        "lecturas" => array:1 [
          "total" => 0
        ]
        "idiomaDefecto" => "es"
        "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0001731019300638?idApp=UINPBA000044"
      ]
    ]
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219019301635?idApp=UINPBA000044"
    "url" => "/15782190/0000011000000006/v1_201907040838/S1578219019301635/v1_201907040838/en/main.assets"
  ]
  "itemAnterior" => array:19 [
    "pii" => "S1578219019301702"
    "issn" => "15782190"
    "doi" => "10.1016/j.adengl.2019.05.008"
    "estado" => "S300"
    "fechaPublicacion" => "2019-07-01"
    "aid" => "2184"
    "copyright" => "Elsevier Espa&#241;a&#44; S&#46;L&#46;U&#46; and AEDV"
    "documento" => "article"
    "crossmark" => 1
    "subdocumento" => "fla"
    "cita" => "Actas Dermosifiliogr. 2019;110:469-73"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:1 [
      "total" => 0
    ]
    "en" => array:12 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">Original Article</span>"
      "titulo" => "Recommendations on Testing Before Outpatient Dermatologic Surgery"
      "tienePdf" => "en"
      "tieneTextoCompleto" => "en"
      "tieneResumen" => array:2 [
        0 => "en"
        1 => "es"
      ]
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "469"
          "paginaFinal" => "473"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "es" => array:1 [
          "titulo" => "Recomendaciones en la petici&#243;n de pruebas preoperatorias en cirug&#237;a dermatol&#243;gica ambulatoria"
        ]
      ]
      "contieneResumen" => array:2 [
        "en" => true
        "es" => true
      ]
      "contieneTextoCompleto" => array:1 [
        "en" => true
      ]
      "contienePdf" => array:1 [
        "en" => true
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "L&#46;M&#46; Nieto-Benito, P&#46; Vilas-Boas, M&#46; Zaballos, C&#46; Llorente-Parrado, J&#46;A&#46; Avil&#233;s-Izquierdo"
          "autores" => array:5 [
            0 => array:2 [
              "nombre" => "L&#46;M&#46;"
              "apellidos" => "Nieto-Benito"
            ]
            1 => array:2 [
              "nombre" => "P&#46;"
              "apellidos" => "Vilas-Boas"
            ]
            2 => array:2 [
              "nombre" => "M&#46;"
              "apellidos" => "Zaballos"
            ]
            3 => array:2 [
              "nombre" => "C&#46;"
              "apellidos" => "Llorente-Parrado"
            ]
            4 => array:2 [
              "nombre" => "J&#46;A&#46;"
              "apellidos" => "Avil&#233;s-Izquierdo"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "en"
    "Traduccion" => array:1 [
      "es" => array:9 [
        "pii" => "S0001731019301188"
        "doi" => "10.1016/j.ad.2019.02.008"
        "estado" => "S300"
        "subdocumento" => ""
        "abierto" => array:3 [
          "ES" => true
          "ES2" => true
          "LATM" => true
        ]
        "gratuito" => true
        "lecturas" => array:1 [
          "total" => 0
        ]
        "idiomaDefecto" => "es"
        "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0001731019301188?idApp=UINPBA000044"
      ]
    ]
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219019301702?idApp=UINPBA000044"
    "url" => "/15782190/0000011000000006/v1_201907040838/S1578219019301702/v1_201907040838/en/main.assets"
  ]
  "en" => array:20 [
    "idiomaDefecto" => true
    "cabecera" => "<span class="elsevierStyleTextfn">Original Article</span>"
    "titulo" => "Reconstruction of Moderate-Sized Scalp Defects&#58; A 1&#8211;2&#8211;3 Rule"
    "tieneTextoCompleto" => true
    "paginas" => array:1 [
      0 => array:2 [
        "paginaInicial" => "474"
        "paginaFinal" => "481"
      ]
    ]
    "autores" => array:1 [
      0 => array:3 [
        "autoresLista" => "F&#46; Russo"
        "autores" => array:1 [
          0 => array:3 [
            "nombre" => "F&#46;"
            "apellidos" => "Russo"
            "email" => array:1 [
              0 => "russo@aedv.es"
            ]
          ]
        ]
        "afiliaciones" => array:1 [
          0 => array:2 [
            "entidad" => "Servicio de Dermatolog&#237;a&#44; Hospital Punta de Europa&#44; Algeciras&#44; C&#225;diz&#44; Spain"
            "identificador" => "aff0005"
          ]
        ]
      ]
    ]
    "titulosAlternativos" => array:1 [
      "es" => array:1 [
        "titulo" => "Regla &#171;1-2-3&#187; para la reconstrucci&#243;n de defectos de mediano tama&#241;o del cuero cabelludo"
      ]
    ]
    "resumenGrafico" => array:2 [
      "original" => 0
      "multimedia" => array:7 [
        "identificador" => "fig0015"
        "etiqueta" => "Figure 3"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr3.jpeg"
            "Alto" => 2620
            "Ancho" => 1733
            "Tamanyo" => 888662
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0065" class="elsevierStyleSimplePara elsevierViewall">Reconstruction of defects with a minimum side-to-side distance of 3<span class="elsevierStyleHsp" style=""></span>to 4<span class="elsevierStyleHsp" style=""></span>cm after the skin was drawn together manually&#46; A&#44; Begin the process of closing these defects by making 3<span class="elsevierStyleHsp" style=""></span>release incisions&#46; B&#44; Draw the skin together and secure with a single suture&#46; C&#44; Close the release incisions with a Mercedes flap&#46; D&#8211;E&#44; If a Mercedes flap cannot close the defect&#44; prepare a triple Limberg flap&#46; F&#44; Close&#46;</p>"
        ]
      ]
    ]
    "textoCompleto" => "<span class="elsevierStyleSections"><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0065">Introduction</span><p id="par0005" class="elsevierStylePara elsevierViewall">High sun exposure on the scalp&#44; especially in men who are bald&#44; often leads to skin tumors&#44; which are preferably treated by surgical excision&#46; Because the scalp is highly vascularized&#44; flaps that would not be feasible at other sites can be constructed here&#46; Skin pallor after scalp reconstruction does not augur failure or predict necrosis as it does at other locations&#46; Moreover&#44; the subgaleal plane is ideal for flap elevation&#44; and periosteal resection makes it difficult to use skin grafts&#46;</p><p id="par0010" class="elsevierStylePara elsevierViewall">The reconstruction of surgical defects on the scalp is nevertheless challenging for several reasons&#58; anatomical convexity limits tissue displacement&#44; resistance to advancement is different at different points on the scalp&#44; and there is also interindividual variation&#46; Therefore&#44; the natural diameter of the defect is not the best criterion to consider when choosing a reconstruction technique&#46; As a consequence&#44; a surgeon beginning the process of reconstruction first manually pulls the sides of the scalp defect closer together to determine the minimum distance that can be achieved between them &#40;<a class="elsevierStyleCrossRef" href="#fig0005">Fig&#46; 1</a>A&#41;&#46; The utility of this maneuver&#44; which gives an overall idea of both the defect&#39;s diameter and the skin tension in the region&#44; is analyzed in this paper&#46;</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia></span><span id="sec0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0070">Materials and Methods</span><p id="par0015" class="elsevierStylePara elsevierViewall">Records were analyzed for 119 patients who underwent surgical excision of scalp tumors between 2007 and 2017&#46; Although a total of 725 scalp tumors had been excised&#44; cases were excluded if the first choice for defect closure was a simple suture&#44; granulation &#40;secondary-intention healing&#41;&#44; or a skin graft&#46;</p><p id="par0020" class="elsevierStylePara elsevierViewall">The cases were classified in 5 groups according to the minimum manually achievable distance between the sides of the defect&#58; less than 1<span class="elsevierStyleHsp" style=""></span>cm&#44; between 1<span class="elsevierStyleHsp" style=""></span>and 2<span class="elsevierStyleHsp" style=""></span>cm&#44; from 2<span class="elsevierStyleHsp" style=""></span>to 3<span class="elsevierStyleHsp" style=""></span>cm&#44; from 3<span class="elsevierStyleHsp" style=""></span>to 4<span class="elsevierStyleHsp" style=""></span>cm&#44; and more than 4<span class="elsevierStyleHsp" style=""></span>cm&#46;</p><p id="par0025" class="elsevierStylePara elsevierViewall">Outcomes evaluated were the rate of use of the simplest feasible technique for closing the defect in each minimum-distance group&#44; the results observed during follow-up&#44; early and late complications&#44; and final cosmetic results&#46;</p><p id="par0030" class="elsevierStylePara elsevierViewall">Most defects with minimum achievable side-to-side distances of less than 1<span class="elsevierStyleHsp" style=""></span>cm were closed with a single suture of mattress stitches reinforced by a sterile aspiration probe placed on either side of the vertical line &#40;<a class="elsevierStyleCrossRef" href="#fig0005">Fig&#46; 1</a>B&#41;&#46; The probes absorbed all the tension in the closure&#44; facilitated traction&#44; and protected the borders from tearing&#46; Very good results were obtained with the reinforced suture&#44; which is simple and accomplished quickly&#44; resolving nearly all small defects of less than 1<span class="elsevierStyleHsp" style=""></span>cm&#46;</p><p id="par0035" class="elsevierStylePara elsevierViewall">When the minimum achievable distance between the sides of the defect was between 1<span class="elsevierStyleHsp" style=""></span>and 2<span class="elsevierStyleHsp" style=""></span>cm&#44; a release incision was made at a distance from the defect that was similar to its diameter &#40;<a class="elsevierStyleCrossRef" href="#fig0005">Fig&#46; 1</a>C&#41;&#46; In many cases this incision provided enough tissue mobility to close both defects using 2 independent sutures&#46; If closure was not possible with this approach&#44; however&#44; the release incision was extended along a curve towards the defect to create a classic rotation flap &#40;<a class="elsevierStyleCrossRef" href="#fig0005">Figs&#46; 1</a>D&#8211;1F&#41;&#46; Another possibility was to make a perpendicular back-incision from the defect to create a Limberg transposition flap&#46; Finally&#44; if necessary&#44; a second such flap could be created on the other side of the defect &#40;a double Limberg&#41; or an O-to-Z rotation flap could be designed&#46; Such techniques were not usually required in this group&#44; however&#46;</p><p id="par0040" class="elsevierStylePara elsevierViewall">When the minimum achievable side-to-side distance was between 2<span class="elsevierStyleHsp" style=""></span>and 3<span class="elsevierStyleHsp" style=""></span>cm&#44; reconstruction started with 2<span class="elsevierStyleHsp" style=""></span>release incisions on either side of the defect&#46; None of the defects in this category could be closed with a single release incision&#59; 2 such incisions were therefore always made and in many cases achieved sufficient advancement to allow the defect to be closed with 3 independent lines of suture &#40;<a class="elsevierStyleCrossRef" href="#fig0010">Figs&#46; 2</a>A and 2B&#41;&#46; If the defect could not be closed with this approach&#44; however&#44; the release incisions were extended along a curve in the direction of the defect &#40;<a class="elsevierStyleCrossRef" href="#fig0010">Fig&#46; 2</a>C&#41; to create a double rotation flap &#40;<a class="elsevierStyleCrossRef" href="#fig0010">Figs&#46; 2</a>D and 2E&#41;&#46; Other defects in this size group were closed by extending the release incisions with a perpendicular back-incision to create double Limberg flaps&#46;</p><elsevierMultimedia ident="fig0010"></elsevierMultimedia><p id="par0045" class="elsevierStylePara elsevierViewall">When the minimum distance between the sides fell between 3<span class="elsevierStyleHsp" style=""></span>and 4<span class="elsevierStyleHsp" style=""></span>cm&#44; 3<span class="elsevierStyleHsp" style=""></span>release incisions were made around the defect &#40;<a class="elsevierStyleCrossRef" href="#fig0015">Fig&#46; 3</a>A&#41;&#46; None of the defects in this group could be closed with either a single or 2 release incisions&#46; Since it is not possible to switch from 2 to 3 release incisions&#44; 3 of them were appropriately distributed around the defect from the start in all the cases in this group&#46; These incisions facilitated closure of the defect using the recently described Mercedes flap<a class="elsevierStyleCrossRef" href="#bib0075"><span class="elsevierStyleSup">1</span></a> &#40;<a class="elsevierStyleCrossRef" href="#fig0015">Figs&#46; 3</a>B and 3C&#41;&#46; If the wound could not be closed with this approach&#44; all 3 incisions were extended along a curve in the direction of one side of the defect&#46; Three flaps were elevated and the defect was closed with a triple rotation flap technique first described in 1971 by Orticochea&#46;<a class="elsevierStyleCrossRef" href="#bib0080"><span class="elsevierStyleSup">2</span></a> As in the groups described above&#44; the release incisions could also be extended by a perpendicular back-incision to create a triple Limberg flap &#40;<a class="elsevierStyleCrossRef" href="#fig0015">Figs&#46; 3</a>D&#8211;3F&#41;&#46;</p><elsevierMultimedia ident="fig0015"></elsevierMultimedia></span><span id="sec0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0075">Results</span><p id="par0050" class="elsevierStylePara elsevierViewall">The distribution of defect sizes and closure techniques is shown in <a class="elsevierStyleCrossRef" href="#fig0020">Fig&#46; 4</a>&#46; The 119 patients studied &#40;102 men&#44; 17 women&#41; ranged in age from 32 to 93 years&#46; The average age was 71 years&#46; Most of the excised tumors were spindle cell squamous carcinomas &#40;89&#41;&#46; There were also basal cell carcinomas &#40;20&#41;&#44; melanomas &#40;7&#41; merkelomas &#40;2&#41;&#44; and a single angiosarcoma&#46; The patients were followed for an average of 42 months &#40;range&#44; 6&#8211;120 months&#41;&#46;</p><elsevierMultimedia ident="fig0020"></elsevierMultimedia><p id="par0055" class="elsevierStylePara elsevierViewall">Thirty-nine of the 119 patients had small surgical defects &#40;minimum achievable side-to-side distance of less than 1<span class="elsevierStyleHsp" style=""></span>cm&#41;&#46; Thirty-one of these cases were closed with a suture reinforced with a sterile aspiration probe on either side of the wound&#46; Five others that were only partly closed with this type of suture were allowed to complete the process by second-intention healing&#46; Flaps were used in 3<span class="elsevierStyleHsp" style=""></span>other cases &#40;1<span class="elsevierStyleHsp" style=""></span>advancement flap and 2<span class="elsevierStyleHsp" style=""></span>rotation flaps&#41;&#46; Results were excellent in most of the 31 cases closed directly with a reinforced suture&#44; but superinfection of the wound complicated 2<span class="elsevierStyleHsp" style=""></span>cases&#46; Somewhat wider&#44; less cosmetically pleasing scars resulted in the 5<span class="elsevierStyleHsp" style=""></span>cases that were allowed to heal by second intention&#46; Surgery lasted longer in the 3<span class="elsevierStyleHsp" style=""></span>flap reconstructions&#44; and one of these incisions reopened 3<span class="elsevierStyleHsp" style=""></span>days later&#46;</p><p id="par0060" class="elsevierStylePara elsevierViewall">The group of defects with minimum achievable side-to-side distances of 1<span class="elsevierStyleHsp" style=""></span>to 2<span class="elsevierStyleHsp" style=""></span>cm comprised 33<span class="elsevierStyleHsp" style=""></span>cases&#46; A single release incision started the process in 22<span class="elsevierStyleHsp" style=""></span>of these cases and closure was completed without a flap in 13<span class="elsevierStyleHsp" style=""></span>of them&#46; The release incision was extended to allow closure with a rotation flap in the 9<span class="elsevierStyleHsp" style=""></span>remaining cases in this group&#44; and that technique provided successful reconstruction in 6 of them&#46; In 2 cases the incision was extended to create a Limberg transposition flap&#44; and in the last of the 9<span class="elsevierStyleHsp" style=""></span>cases a second contralateral rotation flap was required to close the defect with a double O-to-Z rotation flap&#46; No initial release incision was made in 11<span class="elsevierStyleHsp" style=""></span>cases in this 33-patient group&#46; Instead&#44; a rotation flap was immediately chosen for 8 of the 11&#44; and a Limberg transposition flap was used for the other 3&#46; Good cosmetic results were seen in short- and long-term follow-up visits with these patients&#44; except for slight dehiscence in a reconstruction started with a single release incision and in another reconstructed directly with a Limberg flap&#46;</p><p id="par0065" class="elsevierStylePara elsevierViewall">There were 21<span class="elsevierStyleHsp" style=""></span>patients in the group with defects with minimum side-to-side distances of 2<span class="elsevierStyleHsp" style=""></span>to 3<span class="elsevierStyleHsp" style=""></span>cm&#46; Two release incisions were made in 14 of them and were sufficient for closure in 6&#46; In a few cases a single release incision was initially tried but was never sufficient for closure&#59; therefore&#44; a second was made&#46; In another 6<span class="elsevierStyleHsp" style=""></span>in the group of 14<span class="elsevierStyleHsp" style=""></span>patients for whom the 2<span class="elsevierStyleHsp" style=""></span>release incisions were insufficient&#44; the incisions were extended to create 2<span class="elsevierStyleHsp" style=""></span>O-to-Z rotation flaps&#46; The 2<span class="elsevierStyleHsp" style=""></span>remaining patients in the group required extension of the incisions to create 2<span class="elsevierStyleHsp" style=""></span>transposition flaps &#40;1<span class="elsevierStyleHsp" style=""></span>Limberg-type flap and 1<span class="elsevierStyleHsp" style=""></span>bilobed flap&#41;&#46; In the 7<span class="elsevierStyleHsp" style=""></span>remaining cases in this group of 21&#44; a double rotation flap &#40;5<span class="elsevierStyleHsp" style=""></span>cases&#41; or a transposition flap &#40;2<span class="elsevierStyleHsp" style=""></span>cases&#41; was designed directly&#46; No differences were observed in outcomes during follow-up&#44; regardless of whether or not release incisions were made &#40;ie&#44; whether flaps were initially designed or the result of extending the release incisions&#41;&#46; The sutures reopened in only 2 cases repaired by starting with release incisions&#46; A single case of superinfection occurred in a defect closed with a double Limberg flap created by extending the release incisions&#46;</p><p id="par0070" class="elsevierStylePara elsevierViewall">Fourteen patients had defects that measured 3<span class="elsevierStyleHsp" style=""></span>to 4<span class="elsevierStyleHsp" style=""></span>cm from side to side&#46; None of the 14 could be closed with either 1 or 2 release incisions&#46; In 7 of the 14 cases&#44; 3 release incisions were made directly&#44; and they allowed for primary closure of the defect with a Mercedes flap in 3 of them&#46; In the other 4 cases&#44; the release incisions were extended back to the defect to create triple rotation flaps in 2<span class="elsevierStyleHsp" style=""></span>and Limberg transposition rotation flaps in 2&#46; The remaining 7<span class="elsevierStyleHsp" style=""></span>defects were repaired directly with triple Limberg flaps &#40;6<span class="elsevierStyleHsp" style=""></span>cases&#41; or a triple rotation flap &#40;1<span class="elsevierStyleHsp" style=""></span>case&#41;&#46; No differences in outcomes were observed on follow-up&#44; although 1<span class="elsevierStyleHsp" style=""></span>Mercedes flap and 2<span class="elsevierStyleHsp" style=""></span>of the direct Limberg flaps opened up&#46;</p><p id="par0075" class="elsevierStylePara elsevierViewall">Twelve patients had surgical defects measuring more than 4<span class="elsevierStyleHsp" style=""></span>cm even after the sides were pulled together&#46; Reconstruction started with 3 release incisions in 3 of the 12&#44; but as primary closure could not be achieved&#44; triple flaps were designed&#46; Seven cases required skin grafts&#46; Two were left for second-intention healing&#46; Closure with a triple rotation flap was attempted in 2<span class="elsevierStyleHsp" style=""></span>cases&#46; One of them closed partially and a graft was then provided to complete the closure&#46; The twelfth case was reconstructed with a directly designed triple Limberg flap&#46; Follow-up records showed that second-intention healing took more than 6<span class="elsevierStyleHsp" style=""></span>weeks&#46; The outcomes in the cases requiring grafts were good&#44; although partial necrosis developed in 1<span class="elsevierStyleHsp" style=""></span>of the 7<span class="elsevierStyleHsp" style=""></span>cases&#44; and the cosmetic outcome was not ideal in some&#46; Dehiscence occurred in 2<span class="elsevierStyleHsp" style=""></span>of the 3<span class="elsevierStyleHsp" style=""></span>flap reconstructions&#46;</p><p id="par0080" class="elsevierStylePara elsevierViewall">Overall&#44; 13 of the 119 patients &#40;10&#46;92&#37;&#41; experienced some type of complication or poor cosmetic outcome&#44; results that were more frequent in patients with large surgical defects&#46; However&#44; frequency bore no relation to the type of reconstruction technique chosen&#46;</p></span><span id="sec0020" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0080">Discussion</span><p id="par0085" class="elsevierStylePara elsevierViewall">Guidelines and review articles advise on the best reconstruction approach to use in difficult areas on the face&#44;<a class="elsevierStyleCrossRefs" href="#bib0085"><span class="elsevierStyleSup">3&#44;4</span></a> but the closure of surgical defects on the scalp is particularly problematic because of skin tension and poor elasticity&#46; Most clinical guidelines and decision trees use the area of the defect as the basis for choosing the most appropriate technique&#46;<a class="elsevierStyleCrossRefs" href="#bib0095"><span class="elsevierStyleSup">5&#8211;9</span></a> However&#44; this criterion does not take into consideration interindividual variation in skin elasticity or other patient factors such as the zone under the scalp that is affected or the effects of prior treatments &#40;for example&#44; fibrosis after radiotherapy or scaring from previous sutures&#41;&#46; To remedy this problem&#44; this study proposes a new concept&#44; the minimum side-to-side distance when the skin around the defect is drawn together manually&#46; This minimum manually achievable distance between sides reflects a combination of the diameter of the defect and the elasticity of the tissues around it and thus offers an objective criterion for guiding choice of reconstructive technique&#46; To use this approach&#44; the surgeon beginning reconstruction of the defect created by excising a scalp lesion&#44; must first draw the sides of the defect as close together as possible and measure the minimum distance&#46; This maneuver&#44; which surgeons often do unconsciously&#44; should be expressly attended to and measured precisely if it is to provide information on which to base the choice of reconstructive technique&#46;</p><p id="par0090" class="elsevierStylePara elsevierViewall">Another innovative aspect of this approach is the initial employment of release incisions as the first reconstructive step&#46; These extra incisions increase the area that can be advanced&#46; The tissue freed in this way is sufficient to close most defects&#46;</p><p id="par0095" class="elsevierStylePara elsevierViewall">Yet another contribution this approach makes is to facilitate flap design by extending the release incisions in the event that they are insufficient for defect closure&#46; Because these incisions can be transformed&#44; a strategic sequence emerges that starts by trying the simplest effective technique and then adapting it according to individual circumstances&#46;</p><p id="par0100" class="elsevierStylePara elsevierViewall">This retrospective case series shows that large defects&#44; of a minimum distance of more than 4<span class="elsevierStyleHsp" style=""></span>cm&#44; can be closed by either second-intention healing or total skin grafts&#46; Release incisions did not achieve closure of any of these defects&#44; and flap closure&#160;&#8212;whether initially planned or created by extending release incisions&#160;&#8212;was associated with a higher rate of complications&#46; Other options for closing large defects include galeal incisions to facilitate skin displacement&#44; flaps in combination with Burow grafts&#44; tissue expansion&#44;<a class="elsevierStyleCrossRef" href="#bib0120"><span class="elsevierStyleSup">10</span></a> latissimus dorsi pediculated flaps&#44;<a class="elsevierStyleCrossRef" href="#bib0125"><span class="elsevierStyleSup">11</span></a> free flaps&#44;<a class="elsevierStyleCrossRef" href="#bib0130"><span class="elsevierStyleSup">12</span></a> or dermal regeneration systems&#46;<a class="elsevierStyleCrossRef" href="#bib0135"><span class="elsevierStyleSup">13</span></a></p><p id="par0105" class="elsevierStylePara elsevierViewall">The reconstruction decision tree described here&#44; using the minimum manually achievable distance between the sides of a defect as the starting point&#44; is termed the 1&#8211;2&#8211;3 rule for its mnemonic value&#46; To reconstruct defects with a minimum distance between 1<span class="elsevierStyleHsp" style=""></span>and 2<span class="elsevierStyleHsp" style=""></span>cm&#44; start with 1<span class="elsevierStyleHsp" style=""></span>release incision&#59; for defects between 2<span class="elsevierStyleHsp" style=""></span>and 3<span class="elsevierStyleHsp" style=""></span>cm&#44; start with 2<span class="elsevierStyleHsp" style=""></span>incisions&#59; and for those between 3<span class="elsevierStyleHsp" style=""></span>and 4<span class="elsevierStyleHsp" style=""></span>cm&#44; start with 3<span class="elsevierStyleHsp" style=""></span>incisions&#46; If closure cannot be accomplished with the recommended number of release incisions&#44; they can be extended to design rotation or transposition flaps &#40;<a class="elsevierStyleCrossRef" href="#fig0025">Fig&#46; 5</a>&#41;&#46;</p><elsevierMultimedia ident="fig0025"></elsevierMultimedia><p id="par0110" class="elsevierStylePara elsevierViewall">Sixty-eight cases in this series involved mid-sized defects with minimum manually achievable distances between 1<span class="elsevierStyleHsp" style=""></span>and 4<span class="elsevierStyleHsp" style=""></span>cm&#46; Closure was achieved by means of the release incisions in 22 of the 43 cases &#40;51&#37;&#41; in which the reconstruction process started with them&#46; Thus&#44; over half the patients&#8217; defects could be fully closed by using the simplest process&#44; which takes advantage of the mobility afforded by such incisions without resort to flaps&#46;</p><p id="par0115" class="elsevierStylePara elsevierViewall">The proposed stepped and adaptable 1&#8211;2&#8211;3 rule follows a logical sequence that starts by attempting closure with a direct suture&#46; If closure is not possible&#44; the surgeon passes on to the next simplest option&#160;&#8212;a reinforced suture&#46; The next step in the sequence is a release incision&#44; followed if necessary by extending the incision to design a rotation or transposition flap&#46; A fourth option is the design of a contralateral rotation or transposition flap to facilitate movement of a large area of surrounding tissue to close the defect&#46; This stepped approach therefore offers many alternatives incrementally while still ensuring that the simplest possible technique appropriate for each defect will be the one that is used&#46; In contrast&#44; if a complex flap is designed and begun from the start of reconstruction&#44; closure may still be impeded but without the possibility of incrementally adding alternatives&#46;</p><p id="par0120" class="elsevierStylePara elsevierViewall">Naturally&#44; this 1&#8211;2&#8211;3 rule must be adapted to individual cases&#44; according to the patient&#39;s general condition and the surgeon&#39;s preferences&#46; For certain individuals and defects with minimum side-to-side distances between 1<span class="elsevierStyleHsp" style=""></span>and 4<span class="elsevierStyleHsp" style=""></span>cm&#44; skin grafts covering the whole defect or second-intention healing may be good options&#46; However&#44; grafts usually give inferior cosmetic results and are associated with greater risk of necrosis&#46; Second-intention healing&#44; on the other hand&#44; although simple and faster to prepare&#44; requires a much longer period of waiting for scar tissue to form&#44; placing a greater burden on the patient while still giving only modest cosmetic results at the end&#46;</p><p id="par0125" class="elsevierStylePara elsevierViewall">The complication rates in this case series were similar to those reported in another series&#46;<a class="elsevierStyleCrossRef" href="#bib0140"><span class="elsevierStyleSup">14</span></a> Complications were more common in patients with large defects&#44; but no influence of reconstructive technique could be identified&#46; Flaps made by extending the release incisions yielded cosmetic and functional results that were similar to the flaps designed from the start of the process&#46; This observation supports the approach of beginning with release incisions to attempt to close the defect by that means alone and later extending incisions to create flaps only if necessary&#46;</p></span><span id="sec0025" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0085">Limitations</span><p id="par0130" class="elsevierStylePara elsevierViewall">This study is affected by the limitations intrinsic to any retrospective design&#46; The protocol described&#44; starting with release incisions&#44; was not applied to all the scalp defects resolved during the period of the study&#46; Of the 68 patients with defects measuring 1<span class="elsevierStyleHsp" style=""></span>to 4<span class="elsevierStyleHsp" style=""></span>cm&#44; reconstruction started with release incisions in 43&#46; Reconstruction flaps were planned initially for the other patients before the protocol described by the 1&#8211;2&#8211;3 rule was introduced&#46; In addition&#44; the number of patients with large defects &#40;minimum manually achievable distances of 4<span class="elsevierStyleHsp" style=""></span>cm from side to side&#41; was small in comparison with the numbers in other groups&#46; Therefore&#44; it is impossible to draw conclusions about other more complex reconstruction techniques for defects that are large or involve the bone&#46; Initiating reconstruction with release incisions is therefore appropriate only for defect sizes with minimum manually achievable distances of 1<span class="elsevierStyleHsp" style=""></span> to 4<span class="elsevierStyleHsp" style=""></span>cm between sides&#46;</p></span><span id="sec0030" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0090">Conclusions</span><p id="par0135" class="elsevierStylePara elsevierViewall">This stepped approach to choosing the simplest effective technique for closing scalp defects relies on first observing the minimum manually achievable distance between the sides of a defect&#46; The 1&#8211;2&#8211;3 rule indicates the number of release incisions that mark the starting point in the reconstruction process&#44; according to the minimum distance measured&#46; The incisions can be extended to design flaps if necessary&#46;</p></span><span id="sec0035" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0095">Conflicts of Interest</span><p id="par0140" class="elsevierStylePara elsevierViewall">The author declares that he has no conflicts of interest&#46;</p></span></span>"
    "textoCompletoSecciones" => array:1 [
      "secciones" => array:12 [
        0 => array:3 [
          "identificador" => "xres1216314"
          "titulo" => "Abstract"
          "secciones" => array:4 [
            0 => array:2 [
              "identificador" => "abst0005"
              "titulo" => "Background and objective"
            ]
            1 => array:2 [
              "identificador" => "abst0010"
              "titulo" => "Material and methods"
            ]
            2 => array:2 [
              "identificador" => "abst0015"
              "titulo" => "Results"
            ]
            3 => array:2 [
              "identificador" => "abst0020"
              "titulo" => "Conclusions"
            ]
          ]
        ]
        1 => array:2 [
          "identificador" => "xpalclavsec1131865"
          "titulo" => "Keywords"
        ]
        2 => array:3 [
          "identificador" => "xres1216313"
          "titulo" => "Resumen"
          "secciones" => array:4 [
            0 => array:2 [
              "identificador" => "abst0025"
              "titulo" => "Antecedentes y objetivos"
            ]
            1 => array:2 [
              "identificador" => "abst0030"
              "titulo" => "Materiales y m&#233;todos"
            ]
            2 => array:2 [
              "identificador" => "abst0035"
              "titulo" => "Resultados"
            ]
            3 => array:2 [
              "identificador" => "abst0040"
              "titulo" => "Conclusiones"
            ]
          ]
        ]
        3 => array:2 [
          "identificador" => "xpalclavsec1131864"
          "titulo" => "Palabras clave"
        ]
        4 => array:2 [
          "identificador" => "sec0005"
          "titulo" => "Introduction"
        ]
        5 => array:2 [
          "identificador" => "sec0010"
          "titulo" => "Materials and Methods"
        ]
        6 => array:2 [
          "identificador" => "sec0015"
          "titulo" => "Results"
        ]
        7 => array:2 [
          "identificador" => "sec0020"
          "titulo" => "Discussion"
        ]
        8 => array:2 [
          "identificador" => "sec0025"
          "titulo" => "Limitations"
        ]
        9 => array:2 [
          "identificador" => "sec0030"
          "titulo" => "Conclusions"
        ]
        10 => array:2 [
          "identificador" => "sec0035"
          "titulo" => "Conflicts of Interest"
        ]
        11 => array:1 [
          "titulo" => "References"
        ]
      ]
    ]
    "pdfFichero" => "main.pdf"
    "tienePdf" => true
    "fechaRecibido" => "2018-11-18"
    "fechaAceptado" => "2019-01-24"
    "PalabrasClave" => array:2 [
      "en" => array:1 [
        0 => array:4 [
          "clase" => "keyword"
          "titulo" => "Keywords"
          "identificador" => "xpalclavsec1131865"
          "palabras" => array:3 [
            0 => "Scalp surgery"
            1 => "Algorithm"
            2 => "Flaps"
          ]
        ]
      ]
      "es" => array:1 [
        0 => array:4 [
          "clase" => "keyword"
          "titulo" => "Palabras clave"
          "identificador" => "xpalclavsec1131864"
          "palabras" => array:3 [
            0 => "Cirug&#237;a cuero cabelludo"
            1 => "Algoritmo"
            2 => "Colgajos"
          ]
        ]
      ]
    ]
    "tieneResumen" => true
    "resumen" => array:2 [
      "en" => array:3 [
        "titulo" => "Abstract"
        "resumen" => "<span id="abst0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0010">Background and objective</span><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Excision of cutaneous scalp tumors results in surgical defects that are difficult to repair because of poor distensibility in this area of the body&#46; The main aim of this study was to develop a structured algorithm to help choose the best technique for reconstructing scalp defects&#46;</p></span> <span id="abst0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0015">Material and methods</span><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Retrospective study of patients who required surgical reconstruction following excision of a cutaneous scalp tumor&#46; We excluded patients with defects that could be closed by simple direct suture and defects for which it was initially decided to use a skin graft or healing by secondary intention&#46; The defects were classified into 5 groups according to the minimum distance between edges&#46; The different reconstruction techniques used were evaluated in each group&#46; The outcomes analyzed were complete defect closure&#44; intraoperative and postoperative complications&#44; and final aesthetic result&#46;</p></span> <span id="abst0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0020">Results</span><p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">We included 119 patients &#40;102 men and 17 women&#41; with a mean age of 71 years &#40;range&#44; 32&#8211;93 years&#41;&#46; Mean follow-up was 42 months &#40;range&#44; 6&#8211;120 months&#41;&#46; Sixty-eight patients had a moderate-sized defect with a distance between edges of 1 to 4<span class="elsevierStyleHsp" style=""></span>cm&#46; Reconstructions started with relaxation incisions in 43 defects and resulted in the successful closure of 22 of them&#46; Defects with a distance of 1 to 2<span class="elsevierStyleHsp" style=""></span>cm required a single relaxation incision&#46; Two incisions were required for defects with a distance of 2 to 3<span class="elsevierStyleHsp" style=""></span>cm&#44; while 3 incisions were required for those with a distance of 3 to 4<span class="elsevierStyleHsp" style=""></span>cm&#46; In the 21 cases in which relaxation incisions were insufficient to close the defect&#44; the incisions were extended to mobilize the flap to achieve closure&#46; Relaxation incisions alone were insufficient for closing defects with a distance greater than 4<span class="elsevierStyleHsp" style=""></span>cm&#46;</p></span> <span id="abst0020" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0025">Conclusions</span><p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">The 1-2-3 rule can help in choosing the best reconstruction technique for moderate-sized defects based on the principle that 1&#44; 2&#44; or 3 initial relaxation incisions are needed depending on the minimum distance between edges &#40;1-2<span class="elsevierStyleHsp" style=""></span>cm&#44; 2-3<span class="elsevierStyleHsp" style=""></span>cm&#44; or 3-4<span class="elsevierStyleHsp" style=""></span>cm&#41;&#46; In all cases&#44; incision extension to mobilize the corresponding flaps remains an option&#46;</p></span>"
        "secciones" => array:4 [
          0 => array:2 [
            "identificador" => "abst0005"
            "titulo" => "Background and objective"
          ]
          1 => array:2 [
            "identificador" => "abst0010"
            "titulo" => "Material and methods"
          ]
          2 => array:2 [
            "identificador" => "abst0015"
            "titulo" => "Results"
          ]
          3 => array:2 [
            "identificador" => "abst0020"
            "titulo" => "Conclusions"
          ]
        ]
      ]
      "es" => array:3 [
        "titulo" => "Resumen"
        "resumen" => "<span id="abst0025" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0035">Antecedentes y objetivos</span><p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">La extirpaci&#243;n quir&#250;rgica de tumores cut&#225;neos de cuero cabelludo crea defectos dif&#237;ciles de reparar por la poca distensibilidad de la zona&#46; El objetivo principal de este trabajo es conseguir un algoritmo estructurado que permita la elecci&#243;n de la mejor t&#233;cnica reconstructiva para el cierre de los defectos quir&#250;rgicos de cuero cabelludo&#46;</p></span> <span id="abst0030" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0040">Materiales y m&#233;todos</span><p id="spar0030" class="elsevierStyleSimplePara elsevierViewall">Estudio retrospectivo de 119 pacientes que requirieron la extirpaci&#243;n quir&#250;rgica de tumores de cuero cabelludo con posterior reconstrucci&#243;n quir&#250;rgica para el cierre del defecto&#46; Se excluyeron los pacientes con defectos que pudieron ser cerrados mediante sutura directa simple&#44; as&#237; como en los que desde el principio se decidi&#243; emplear injertos cut&#225;neos o se dejaron cerrar por segunda intenci&#243;n&#46; Los defectos se clasificaron en 5 grupos seg&#250;n la distancia m&#237;nima de aproximaci&#243;n de los bordes y se evaluaron en cada grupo las diferentes opciones de reconstrucci&#243;n quir&#250;rgica&#46; Se tuvieron en cuenta como objetivos finales el cierre completo del defecto&#44; las complicaciones intra- y postoperatorias&#44; as&#237; como el resultado est&#233;tico final&#46;</p></span> <span id="abst0035" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0045">Resultados</span><p id="spar0035" class="elsevierStyleSimplePara elsevierViewall">Se incluyeron 119 pacientes &#40;102 varones y 17 mujeres&#41;&#59; edad media 71 a&#241;os &#40;rango&#44; 32-93 a&#241;os&#41;&#46; El seguimiento medio fue de 42 meses &#40;rango&#44; 6-120 meses&#41;&#46; De los 119 pacientes&#44; 68 ten&#237;an defectos de mediano tama&#241;o con una distancia de aproximaci&#243;n entre 1 y 4<span class="elsevierStyleHsp" style=""></span>cm&#46; En 43 de ellos se inici&#243; la reconstrucci&#243;n mediante incisiones de descarga que permitieron el cierre del defecto en 22 casos&#46; Los defectos con distancias de 1 a 2<span class="elsevierStyleHsp" style=""></span>cm necesitaron una sola incisi&#243;n de descarga&#46; Los comprendidos entre 2 y 3<span class="elsevierStyleHsp" style=""></span>cm&#44; 2 incisiones y de 3 a 4<span class="elsevierStyleHsp" style=""></span>cm&#44; 3 incisiones&#46; En los 21 casos que no cerraron a trav&#233;s de las incisiones de descarga&#44; se ampliaron estas incisiones a sus correspondientes colgajos para conseguir el cierre&#46; Ninguno de los defectos mayores de 4<span class="elsevierStyleHsp" style=""></span>cm cerr&#243; solo con las incisiones de descarga&#46;</p></span> <span id="abst0040" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0050">Conclusiones</span><p id="spar0040" class="elsevierStyleSimplePara elsevierViewall">La regla&#171;1-2-3&#187; permite elegir la mejor t&#233;cnica reconstructiva para defectos de mediano tama&#241;o realizando inicialmente 1&#44; 2 o 3 incisiones de descarga seg&#250;n sea la distancia de aproximaci&#243;n de los bordes del defecto entre 1-2<span class="elsevierStyleHsp" style=""></span>cm&#44; entre 2-3<span class="elsevierStyleHsp" style=""></span>cm o entre 3-4<span class="elsevierStyleHsp" style=""></span>cm respectivamente&#44; con la opci&#243;n de ampliar a los colgajos correspondientes si fuera necesario&#46;</p></span>"
        "secciones" => array:4 [
          0 => array:2 [
            "identificador" => "abst0025"
            "titulo" => "Antecedentes y objetivos"
          ]
          1 => array:2 [
            "identificador" => "abst0030"
            "titulo" => "Materiales y m&#233;todos"
          ]
          2 => array:2 [
            "identificador" => "abst0035"
            "titulo" => "Resultados"
          ]
          3 => array:2 [
            "identificador" => "abst0040"
            "titulo" => "Conclusiones"
          ]
        ]
      ]
    ]
    "NotaPie" => array:1 [
      0 => array:2 [
        "etiqueta" => "&#9734;"
        "nota" => "<p class="elsevierStyleNotepara" id="npar0005">Please cite this article as&#58; Russo F&#46; Regla &#171;1-2-3&#187; para la reconstrucci&#243;n de defectos de mediano tama&#241;o del cuero cabelludo&#46; Actas Dermosifiliogr&#46; 2019&#59;110&#58;474&#8211;481&#46;</p>"
      ]
    ]
    "multimedia" => array:5 [
      0 => array:7 [
        "identificador" => "fig0005"
        "etiqueta" => "Figure 1"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr1.jpeg"
            "Alto" => 2240
            "Ancho" => 1733
            "Tamanyo" => 618223
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0045" class="elsevierStyleSimplePara elsevierViewall">Reconstruction of defects with a minimum side-to-side distance less than 2<span class="elsevierStyleHsp" style=""></span>cm after the skin was drawn together manually&#46; A&#44; Measuring the minimum achievable distance between sides&#46; B&#44; A probe-reinforced suture is recommended for distances less than 1<span class="elsevierStyleHsp" style=""></span>cm&#46; C&#44; Defects measuring between 1<span class="elsevierStyleHsp" style=""></span>and 2<span class="elsevierStyleHsp" style=""></span>cm may require a release incision&#46; D&#8211;F&#44; If closure is still not possible&#44; a rotation flap can be used&#46;</p>"
        ]
      ]
      1 => array:7 [
        "identificador" => "fig0010"
        "etiqueta" => "Figure 2"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr2.jpeg"
            "Alto" => 2304
            "Ancho" => 1733
            "Tamanyo" => 452744
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0055" class="elsevierStyleSimplePara elsevierViewall">Reconstruction of defects with a minimum side-to-side distance of 2<span class="elsevierStyleHsp" style=""></span>to 3<span class="elsevierStyleHsp" style=""></span>cm after the skin was drawn together manually&#46;</p> <p id="spar0060" class="elsevierStyleSimplePara elsevierViewall">A&#44; Begin the process of closing these defects by making 2<span class="elsevierStyleHsp" style=""></span>release incisions&#46; B&#44; After elevating the tissue&#44; close with sutures&#46; C&#8211;D&#44; If that approach fails&#44; design a double O-to-Z rotation flap&#46; E&#44; Close&#46;</p>"
        ]
      ]
      2 => array:7 [
        "identificador" => "fig0015"
        "etiqueta" => "Figure 3"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr3.jpeg"
            "Alto" => 2620
            "Ancho" => 1733
            "Tamanyo" => 888662
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0065" class="elsevierStyleSimplePara elsevierViewall">Reconstruction of defects with a minimum side-to-side distance of 3<span class="elsevierStyleHsp" style=""></span>to 4<span class="elsevierStyleHsp" style=""></span>cm after the skin was drawn together manually&#46; A&#44; Begin the process of closing these defects by making 3<span class="elsevierStyleHsp" style=""></span>release incisions&#46; B&#44; Draw the skin together and secure with a single suture&#46; C&#44; Close the release incisions with a Mercedes flap&#46; D&#8211;E&#44; If a Mercedes flap cannot close the defect&#44; prepare a triple Limberg flap&#46; F&#44; Close&#46;</p>"
        ]
      ]
      3 => array:7 [
        "identificador" => "fig0020"
        "etiqueta" => "Figure 4"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr4.jpeg"
            "Alto" => 1607
            "Ancho" => 3125
            "Tamanyo" => 255274
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0070" class="elsevierStyleSimplePara elsevierViewall">Surgical defect reconstruction techniques used in the 119<span class="elsevierStyleHsp" style=""></span>patients in the series&#46;</p>"
        ]
      ]
      4 => array:7 [
        "identificador" => "fig0025"
        "etiqueta" => "Figure 5"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr5.jpeg"
            "Alto" => 1275
            "Ancho" => 2500
            "Tamanyo" => 195527
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0075" class="elsevierStyleSimplePara elsevierViewall">The 1&#8211;2&#8211;3 rule for reconstructing scalp defects&#46;</p> <p id="spar0080" class="elsevierStyleSimplePara elsevierViewall">Reconstruction of defects with a minimum side-to-side distance of 1 to 2<span class="elsevierStyleHsp" style=""></span>cm starts with a single release incision that can be extended to create a rotation or transposition flap if necessary&#46; Reconstruction of defects with a minimum side-to-side distance of 2 to 3<span class="elsevierStyleHsp" style=""></span>cm starts with 2 release incisions&#44; which can be extended to create double rotation or transposition flaps&#46; Reconstruction of defects with a minimum side-to-side distance of 3 to 4<span class="elsevierStyleHsp" style=""></span>cm starts with 3 release incisions&#44; which can be extended to provide triple rotation or transposition flaps if necessary&#46;</p>"
        ]
      ]
    ]
    "bibliografia" => array:2 [
      "titulo" => "References"
      "seccion" => array:1 [
        0 => array:2 [
          "identificador" => "bibs0015"
          "bibliografiaReferencia" => array:14 [
            0 => array:3 [
              "identificador" => "bib0075"
              "etiqueta" => "1"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Mercedes flap with releasing incisions for scalp defects"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "F&#46; Russo"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1097/SAP.0000000000001053"
                      "Revista" => array:6 [
                        "tituloSerie" => "Ann Plast Surg&#46;"
                        "fecha" => "2017"
                        "volumen" => "79"
                        "paginaInicial" => "149"
                        "paginaFinal" => "155"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/28328636"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            1 => array:3 [
              "identificador" => "bib0080"
              "etiqueta" => "2"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "New three-flap reconstruction technique"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "M&#46; Orticochea"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:4 [
                        "tituloSerie" => "Br J Plast Surg"
                        "fecha" => "1971"
                        "volumen" => "24"
                        "paginaInicial" => "184"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            2 => array:3 [
              "identificador" => "bib0085"
              "etiqueta" => "3"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Reconstruction of facial structures"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "S&#46;R&#46; Baker"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Libro" => array:7 [
                        "edicion" => "2nd ed"
                        "titulo" => "Local flaps in facial reconstruction&#46;"
                        "fecha" => "2007"
                        "paginaInicial" => "385"
                        "paginaFinal" => "637"
                        "editorial" => "Mosby &#40;Elsevier&#41;"
                        "editorialLocalizacion" => "Philadelphia"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            3 => array:3 [
              "identificador" => "bib0090"
              "etiqueta" => "4"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Reconstruction techniques of choice for the facial cosmetic units"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "F&#46; Russo"
                            1 => "M&#46; Linares"
                            2 => "M&#46;E&#46; Iglesias"
                            3 => "J&#46;L&#46; Mart&#237;nez-Amo"
                            4 => "F&#46; Cabo"
                            5 => "J&#46; Tercedor"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Actas Dermosifiliogr&#46;"
                        "fecha" => "2017"
                        "volumen" => "108"
                        "paginaInicial" => "729"
                        "paginaFinal" => "737"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            4 => array:3 [
              "identificador" => "bib0095"
              "etiqueta" => "5"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "An algorithm for oncologic scalp reconstruction"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "N&#46; Iblher"
                            1 => "M&#46;C&#46; Ziegler"
                            2 => "V&#46; Penna"
                            3 => "S&#46;U&#46; Eisenhardt"
                            4 => "G&#46;B&#46; Stark"
                            5 => "H&#46; Bannasch"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1097/PRS.0b013e3181e09515"
                      "Revista" => array:6 [
                        "tituloSerie" => "Plast Reconstr Surg"
                        "fecha" => "2010"
                        "volumen" => "126"
                        "paginaInicial" => "450"
                        "paginaFinal" => "459"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/20679829"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            5 => array:3 [
              "identificador" => "bib0100"
              "etiqueta" => "6"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Can we put a simplified algorithm for reconstruction of large scalp defects following tumor resection&#63;"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "A&#46; Denewer"
                            1 => "A&#46; Khater"
                            2 => "O&#46; Farouk"
                            3 => "M&#46; Hegazy"
                            4 => "M&#46; Mosbah"
                            5 => "M&#46; Hafez"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:4 [
                        "tituloSerie" => "World J Surg Oncol"
                        "fecha" => "2011"
                        "volumen" => "9"
                        "paginaInicial" => "129"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            6 => array:3 [
              "identificador" => "bib0105"
              "etiqueta" => "7"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Reconstruction of acquired scalp defects&#58; An algorithmic approach"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "J&#46;E&#46; Leedy"
                            1 => "J&#46;E&#46; Janis"
                            2 => "R&#46;J&#46; Rohrich"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Plast Reconstr Surg&#46;"
                        "fecha" => "2005"
                        "volumen" => "116"
                        "paginaInicial" => "54e"
                        "paginaFinal" => "72e"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            7 => array:3 [
              "identificador" => "bib0110"
              "etiqueta" => "8"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Current options in head and neck reconstruction"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "K&#46;A&#46; Hurvitz"
                            1 => "M&#46; Kobayashi"
                            2 => "G&#46;R&#46; Evans"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Plast Reconstr Surg&#46;"
                        "fecha" => "2006"
                        "volumen" => "118"
                        "paginaInicial" => "122e"
                        "paginaFinal" => "133e"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            8 => array:3 [
              "identificador" => "bib0115"
              "etiqueta" => "9"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Scalp reconstruction&#58; A 15-year experience"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "M&#46;I&#46; Newman"
                            1 => "M&#46;M&#46; Hanasono"
                            2 => "J&#46;J&#46; Disa"
                            3 => "P&#46;G&#46; Cordeiro"
                            4 => "B&#46;J&#46; Mehrara"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Ann Plast Surg"
                        "fecha" => "2004"
                        "volumen" => "52"
                        "paginaInicial" => "501"
                        "paginaFinal" => "506"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15096938"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            9 => array:3 [
              "identificador" => "bib0120"
              "etiqueta" => "10"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Scalp stretching with a tissue expander for closure of scalp defects"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "R&#46;E&#46;A&#46; Nordstrom"
                            1 => "J&#46;W&#46; Devine"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Plast Reconstr Surg"
                        "fecha" => "1985"
                        "volumen" => "75"
                        "paginaInicial" => "578"
                        "paginaFinal" => "581"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            10 => array:3 [
              "identificador" => "bib0125"
              "etiqueta" => "11"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Management of large scalp defects with local pedicle flaps"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "M&#46;A&#46; Lesavoy"
                            1 => "T&#46;J&#46; Dubrow"
                            2 => "R&#46;J&#46; Schwartz"
                            3 => "P&#46;A&#46; Wackym"
                            4 => "D&#46;M&#46; Eisenhauer"
                            5 => "M&#46; McGuire"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Plast Reconstr Surg"
                        "fecha" => "1993"
                        "volumen" => "91"
                        "paginaInicial" => "783"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8460180"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            11 => array:3 [
              "identificador" => "bib0130"
              "etiqueta" => "12"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Reconstruction of scalp defects with free flaps in 30 cases"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "B&#46;S&#46; Lutz"
                            1 => "F&#46;C&#46; Wei"
                            2 => "H&#46;C&#46; Chen"
                            3 => "C&#46;H&#46; Lin"
                            4 => "C&#46;Y&#46; Wei"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Br J Plast Surg&#46;"
                        "fecha" => "1998"
                        "volumen" => "51"
                        "paginaInicial" => "186"
                        "paginaFinal" => "190"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            12 => array:3 [
              "identificador" => "bib0135"
              "etiqueta" => "13"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Use of dermal regeneration template &#40;Integra&#41; for reconstruction of full-thickness complex oncologic scalp defects"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "M&#46;A&#46; Khan"
                            1 => "S&#46;N&#46; Ali"
                            2 => "M&#46; Farid"
                            3 => "M&#46; Pancholi"
                            4 => "S&#46; Rayatt"
                            5 => "L&#46;H&#46; Yap"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "J Craniofac Surg"
                        "fecha" => "2010"
                        "volumen" => "21"
                        "paginaInicial" => "905"
                        "paginaFinal" => "909"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            13 => array:3 [
              "identificador" => "bib0140"
              "etiqueta" => "14"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Complications after oncologic scalp reconstruction&#58; A 139-patient series and treatment algorithm"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "J&#46;R&#46; Janus"
                            1 => "B&#46;W&#46; Peck"
                            2 => "N&#46;M&#46; Tombers"
                            3 => "D&#46;L&#46; Price"
                            4 => "E&#46;J&#46; Moore"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Laryngoscope&#46;"
                        "fecha" => "2015"
                        "volumen" => "125"
                        "paginaInicial" => "582"
                        "paginaFinal" => "588"
                      ]
                    ]
                  ]
                ]
              ]
            ]
          ]
        ]
      ]
    ]
  ]
  "idiomaDefecto" => "en"
  "url" => "/15782190/0000011000000006/v1_201907040838/S1578219019301490/v1_201907040838/en/main.assets"
  "Apartado" => array:4 [
    "identificador" => "6155"
    "tipo" => "SECCION"
    "en" => array:2 [
      "titulo" => "Original Articles"
      "idiomaDefecto" => true
    ]
    "idiomaDefecto" => "en"
  ]
  "PDF" => "https://static.elsevier.es/multimedia/15782190/0000011000000006/v1_201907040838/S1578219019301490/v1_201907040838/en/main.pdf?idApp=UINPBA000044&text.app=https://actasdermo.org/"
  "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219019301490?idApp=UINPBA000044"
]
Compartir
Información de la revista

Estadísticas

Siga este enlace para acceder al texto completo del artículo

Original Article
Reconstruction of Moderate-Sized Scalp Defects: A 1–2–3 Rule
Regla «1-2-3» para la reconstrucción de defectos de mediano tamaño del cuero cabelludo
F. Russo
Servicio de Dermatología, Hospital Punta de Europa, Algeciras, Cádiz, Spain
Leído
13195
Veces
se ha leído el artículo
2781
Total PDF
10414
Total HTML
Compartir estadísticas
 array:24 [
  "pii" => "S1578219019301490"
  "issn" => "15782190"
  "doi" => "10.1016/j.adengl.2019.05.002"
  "estado" => "S300"
  "fechaPublicacion" => "2019-07-01"
  "aid" => "2149"
  "copyright" => "Elsevier Espa&#241;a&#44; S&#46;L&#46;U&#46; and AEDV"
  "copyrightAnyo" => "2019"
  "documento" => "article"
  "crossmark" => 1
  "subdocumento" => "fla"
  "cita" => "Actas Dermosifiliogr. 2019;110:474-81"
  "abierto" => array:3 [
    "ES" => true
    "ES2" => true
    "LATM" => true
  ]
  "gratuito" => true
  "lecturas" => array:2 [
    "total" => 1
    "HTML" => 1
  ]
  "Traduccion" => array:1 [
    "es" => array:19 [
      "pii" => "S0001731019300602"
      "issn" => "00017310"
      "doi" => "10.1016/j.ad.2019.01.002"
      "estado" => "S300"
      "fechaPublicacion" => "2019-07-01"
      "aid" => "2149"
      "copyright" => "AEDV"
      "documento" => "article"
      "crossmark" => 1
      "subdocumento" => "fla"
      "cita" => "Actas Dermosifiliogr. 2019;110:474-81"
      "abierto" => array:3 [
        "ES" => true
        "ES2" => true
        "LATM" => true
      ]
      "gratuito" => true
      "lecturas" => array:2 [
        "total" => 562
        "formatos" => array:2 [
          "HTML" => 368
          "PDF" => 194
        ]
      ]
      "es" => array:14 [
        "idiomaDefecto" => true
        "cabecera" => "<span class="elsevierStyleTextfn">Original</span>"
        "titulo" => "Regla &#171;1-2-3&#187; para la reconstrucci&#243;n de defectos de mediano tama&#241;o del cuero cabelludo"
        "tienePdf" => "es"
        "tieneTextoCompleto" => "es"
        "tieneResumen" => array:3 [
          0 => "es"
          1 => "es"
          2 => "en"
        ]
        "paginas" => array:1 [
          0 => array:2 [
            "paginaInicial" => "474"
            "paginaFinal" => "481"
          ]
        ]
        "titulosAlternativos" => array:1 [
          "en" => array:1 [
            "titulo" => "Reconstruction of Moderate-Sized Scalp Defects&#58; A 1-2-3 Rule"
          ]
        ]
        "contieneResumen" => array:2 [
          "es" => true
          "en" => true
        ]
        "contieneTextoCompleto" => array:1 [
          "es" => true
        ]
        "contienePdf" => array:1 [
          "es" => true
        ]
        "resumenGrafico" => array:2 [
          "original" => 1
          "multimedia" => array:5 [
            "identificador" => "fig0030"
            "tipo" => "MULTIMEDIAFIGURA"
            "mostrarFloat" => false
            "mostrarDisplay" => true
            "figura" => array:1 [
              0 => array:4 [
                "imagen" => "fx1.jpeg"
                "Alto" => 679
                "Ancho" => 1333
                "Tamanyo" => 66035
              ]
            ]
          ]
        ]
        "autores" => array:1 [
          0 => array:2 [
            "autoresLista" => "F&#46; Russo"
            "autores" => array:1 [
              0 => array:2 [
                "nombre" => "F&#46;"
                "apellidos" => "Russo"
              ]
            ]
          ]
        ]
        "resumen" => array:1 [
          0 => array:3 [
            "titulo" => "Graphical abstract"
            "clase" => "graphical"
            "resumen" => "<span id="abst0005" class="elsevierStyleSection elsevierViewall"><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall"><elsevierMultimedia ident="fig0030"></elsevierMultimedia></p></span>"
          ]
        ]
      ]
      "idiomaDefecto" => "es"
      "Traduccion" => array:1 [
        "en" => array:9 [
          "pii" => "S1578219019301490"
          "doi" => "10.1016/j.adengl.2019.05.002"
          "estado" => "S300"
          "subdocumento" => ""
          "abierto" => array:3 [
            "ES" => true
            "ES2" => true
            "LATM" => true
          ]
          "gratuito" => true
          "lecturas" => array:1 [
            "total" => 0
          ]
          "idiomaDefecto" => "en"
          "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219019301490?idApp=UINPBA000044"
        ]
      ]
      "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0001731019300602?idApp=UINPBA000044"
      "url" => "/00017310/0000011000000006/v1_201907020633/S0001731019300602/v1_201907020633/es/main.assets"
    ]
  ]
  "itemSiguiente" => array:19 [
    "pii" => "S1578219019301635"
    "issn" => "15782190"
    "doi" => "10.1016/j.adengl.2019.01.016"
    "estado" => "S300"
    "fechaPublicacion" => "2019-07-01"
    "aid" => "2152"
    "copyright" => "Elsevier Espa&#241;a&#44; S&#46;L&#46;U&#46; and AEDV"
    "documento" => "article"
    "crossmark" => 1
    "subdocumento" => "fla"
    "cita" => "Actas Dermosifiliogr. 2019;110:482-9"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:2 [
      "total" => 1
      "HTML" => 1
    ]
    "en" => array:12 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">Original Article</span>"
      "titulo" => "Complications and Sequelae After Sentinel Lymph Node Biopsy in Melanoma&#58; A Retrospective Cohort Study"
      "tienePdf" => "en"
      "tieneTextoCompleto" => "en"
      "tieneResumen" => array:2 [
        0 => "en"
        1 => "es"
      ]
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "482"
          "paginaFinal" => "489"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "es" => array:1 [
          "titulo" => "Complicaciones y secuelas de la t&#233;cnica de biopsia selectiva del ganglio centinela para el melanoma en una cohorte retrospectiva"
        ]
      ]
      "contieneResumen" => array:2 [
        "en" => true
        "es" => true
      ]
      "contieneTextoCompleto" => array:1 [
        "en" => true
      ]
      "contienePdf" => array:1 [
        "en" => true
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "C&#46;E&#46; Espinosa-Pereiro, A&#46; Zulaica G&#225;rate, I&#46; Garc&#237;a-Doval"
          "autores" => array:3 [
            0 => array:2 [
              "nombre" => "C&#46;E&#46;"
              "apellidos" => "Espinosa-Pereiro"
            ]
            1 => array:2 [
              "nombre" => "A&#46;"
              "apellidos" => "Zulaica G&#225;rate"
            ]
            2 => array:2 [
              "nombre" => "I&#46;"
              "apellidos" => "Garc&#237;a-Doval"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "en"
    "Traduccion" => array:1 [
      "es" => array:9 [
        "pii" => "S0001731019300638"
        "doi" => "10.1016/j.ad.2019.01.003"
        "estado" => "S300"
        "subdocumento" => ""
        "abierto" => array:3 [
          "ES" => true
          "ES2" => true
          "LATM" => true
        ]
        "gratuito" => true
        "lecturas" => array:1 [
          "total" => 0
        ]
        "idiomaDefecto" => "es"
        "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0001731019300638?idApp=UINPBA000044"
      ]
    ]
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219019301635?idApp=UINPBA000044"
    "url" => "/15782190/0000011000000006/v1_201907040838/S1578219019301635/v1_201907040838/en/main.assets"
  ]
  "itemAnterior" => array:19 [
    "pii" => "S1578219019301702"
    "issn" => "15782190"
    "doi" => "10.1016/j.adengl.2019.05.008"
    "estado" => "S300"
    "fechaPublicacion" => "2019-07-01"
    "aid" => "2184"
    "copyright" => "Elsevier Espa&#241;a&#44; S&#46;L&#46;U&#46; and AEDV"
    "documento" => "article"
    "crossmark" => 1
    "subdocumento" => "fla"
    "cita" => "Actas Dermosifiliogr. 2019;110:469-73"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:1 [
      "total" => 0
    ]
    "en" => array:12 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">Original Article</span>"
      "titulo" => "Recommendations on Testing Before Outpatient Dermatologic Surgery"
      "tienePdf" => "en"
      "tieneTextoCompleto" => "en"
      "tieneResumen" => array:2 [
        0 => "en"
        1 => "es"
      ]
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "469"
          "paginaFinal" => "473"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "es" => array:1 [
          "titulo" => "Recomendaciones en la petici&#243;n de pruebas preoperatorias en cirug&#237;a dermatol&#243;gica ambulatoria"
        ]
      ]
      "contieneResumen" => array:2 [
        "en" => true
        "es" => true
      ]
      "contieneTextoCompleto" => array:1 [
        "en" => true
      ]
      "contienePdf" => array:1 [
        "en" => true
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "L&#46;M&#46; Nieto-Benito, P&#46; Vilas-Boas, M&#46; Zaballos, C&#46; Llorente-Parrado, J&#46;A&#46; Avil&#233;s-Izquierdo"
          "autores" => array:5 [
            0 => array:2 [
              "nombre" => "L&#46;M&#46;"
              "apellidos" => "Nieto-Benito"
            ]
            1 => array:2 [
              "nombre" => "P&#46;"
              "apellidos" => "Vilas-Boas"
            ]
            2 => array:2 [
              "nombre" => "M&#46;"
              "apellidos" => "Zaballos"
            ]
            3 => array:2 [
              "nombre" => "C&#46;"
              "apellidos" => "Llorente-Parrado"
            ]
            4 => array:2 [
              "nombre" => "J&#46;A&#46;"
              "apellidos" => "Avil&#233;s-Izquierdo"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "en"
    "Traduccion" => array:1 [
      "es" => array:9 [
        "pii" => "S0001731019301188"
        "doi" => "10.1016/j.ad.2019.02.008"
        "estado" => "S300"
        "subdocumento" => ""
        "abierto" => array:3 [
          "ES" => true
          "ES2" => true
          "LATM" => true
        ]
        "gratuito" => true
        "lecturas" => array:1 [
          "total" => 0
        ]
        "idiomaDefecto" => "es"
        "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0001731019301188?idApp=UINPBA000044"
      ]
    ]
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219019301702?idApp=UINPBA000044"
    "url" => "/15782190/0000011000000006/v1_201907040838/S1578219019301702/v1_201907040838/en/main.assets"
  ]
  "en" => array:20 [
    "idiomaDefecto" => true
    "cabecera" => "<span class="elsevierStyleTextfn">Original Article</span>"
    "titulo" => "Reconstruction of Moderate-Sized Scalp Defects&#58; A 1&#8211;2&#8211;3 Rule"
    "tieneTextoCompleto" => true
    "paginas" => array:1 [
      0 => array:2 [
        "paginaInicial" => "474"
        "paginaFinal" => "481"
      ]
    ]
    "autores" => array:1 [
      0 => array:3 [
        "autoresLista" => "F&#46; Russo"
        "autores" => array:1 [
          0 => array:3 [
            "nombre" => "F&#46;"
            "apellidos" => "Russo"
            "email" => array:1 [
              0 => "russo@aedv.es"
            ]
          ]
        ]
        "afiliaciones" => array:1 [
          0 => array:2 [
            "entidad" => "Servicio de Dermatolog&#237;a&#44; Hospital Punta de Europa&#44; Algeciras&#44; C&#225;diz&#44; Spain"
            "identificador" => "aff0005"
          ]
        ]
      ]
    ]
    "titulosAlternativos" => array:1 [
      "es" => array:1 [
        "titulo" => "Regla &#171;1-2-3&#187; para la reconstrucci&#243;n de defectos de mediano tama&#241;o del cuero cabelludo"
      ]
    ]
    "resumenGrafico" => array:2 [
      "original" => 0
      "multimedia" => array:7 [
        "identificador" => "fig0015"
        "etiqueta" => "Figure 3"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr3.jpeg"
            "Alto" => 2620
            "Ancho" => 1733
            "Tamanyo" => 888662
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0065" class="elsevierStyleSimplePara elsevierViewall">Reconstruction of defects with a minimum side-to-side distance of 3<span class="elsevierStyleHsp" style=""></span>to 4<span class="elsevierStyleHsp" style=""></span>cm after the skin was drawn together manually&#46; A&#44; Begin the process of closing these defects by making 3<span class="elsevierStyleHsp" style=""></span>release incisions&#46; B&#44; Draw the skin together and secure with a single suture&#46; C&#44; Close the release incisions with a Mercedes flap&#46; D&#8211;E&#44; If a Mercedes flap cannot close the defect&#44; prepare a triple Limberg flap&#46; F&#44; Close&#46;</p>"
        ]
      ]
    ]
    "textoCompleto" => "<span class="elsevierStyleSections"><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0065">Introduction</span><p id="par0005" class="elsevierStylePara elsevierViewall">High sun exposure on the scalp&#44; especially in men who are bald&#44; often leads to skin tumors&#44; which are preferably treated by surgical excision&#46; Because the scalp is highly vascularized&#44; flaps that would not be feasible at other sites can be constructed here&#46; Skin pallor after scalp reconstruction does not augur failure or predict necrosis as it does at other locations&#46; Moreover&#44; the subgaleal plane is ideal for flap elevation&#44; and periosteal resection makes it difficult to use skin grafts&#46;</p><p id="par0010" class="elsevierStylePara elsevierViewall">The reconstruction of surgical defects on the scalp is nevertheless challenging for several reasons&#58; anatomical convexity limits tissue displacement&#44; resistance to advancement is different at different points on the scalp&#44; and there is also interindividual variation&#46; Therefore&#44; the natural diameter of the defect is not the best criterion to consider when choosing a reconstruction technique&#46; As a consequence&#44; a surgeon beginning the process of reconstruction first manually pulls the sides of the scalp defect closer together to determine the minimum distance that can be achieved between them &#40;<a class="elsevierStyleCrossRef" href="#fig0005">Fig&#46; 1</a>A&#41;&#46; The utility of this maneuver&#44; which gives an overall idea of both the defect&#39;s diameter and the skin tension in the region&#44; is analyzed in this paper&#46;</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia></span><span id="sec0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0070">Materials and Methods</span><p id="par0015" class="elsevierStylePara elsevierViewall">Records were analyzed for 119 patients who underwent surgical excision of scalp tumors between 2007 and 2017&#46; Although a total of 725 scalp tumors had been excised&#44; cases were excluded if the first choice for defect closure was a simple suture&#44; granulation &#40;secondary-intention healing&#41;&#44; or a skin graft&#46;</p><p id="par0020" class="elsevierStylePara elsevierViewall">The cases were classified in 5 groups according to the minimum manually achievable distance between the sides of the defect&#58; less than 1<span class="elsevierStyleHsp" style=""></span>cm&#44; between 1<span class="elsevierStyleHsp" style=""></span>and 2<span class="elsevierStyleHsp" style=""></span>cm&#44; from 2<span class="elsevierStyleHsp" style=""></span>to 3<span class="elsevierStyleHsp" style=""></span>cm&#44; from 3<span class="elsevierStyleHsp" style=""></span>to 4<span class="elsevierStyleHsp" style=""></span>cm&#44; and more than 4<span class="elsevierStyleHsp" style=""></span>cm&#46;</p><p id="par0025" class="elsevierStylePara elsevierViewall">Outcomes evaluated were the rate of use of the simplest feasible technique for closing the defect in each minimum-distance group&#44; the results observed during follow-up&#44; early and late complications&#44; and final cosmetic results&#46;</p><p id="par0030" class="elsevierStylePara elsevierViewall">Most defects with minimum achievable side-to-side distances of less than 1<span class="elsevierStyleHsp" style=""></span>cm were closed with a single suture of mattress stitches reinforced by a sterile aspiration probe placed on either side of the vertical line &#40;<a class="elsevierStyleCrossRef" href="#fig0005">Fig&#46; 1</a>B&#41;&#46; The probes absorbed all the tension in the closure&#44; facilitated traction&#44; and protected the borders from tearing&#46; Very good results were obtained with the reinforced suture&#44; which is simple and accomplished quickly&#44; resolving nearly all small defects of less than 1<span class="elsevierStyleHsp" style=""></span>cm&#46;</p><p id="par0035" class="elsevierStylePara elsevierViewall">When the minimum achievable distance between the sides of the defect was between 1<span class="elsevierStyleHsp" style=""></span>and 2<span class="elsevierStyleHsp" style=""></span>cm&#44; a release incision was made at a distance from the defect that was similar to its diameter &#40;<a class="elsevierStyleCrossRef" href="#fig0005">Fig&#46; 1</a>C&#41;&#46; In many cases this incision provided enough tissue mobility to close both defects using 2 independent sutures&#46; If closure was not possible with this approach&#44; however&#44; the release incision was extended along a curve towards the defect to create a classic rotation flap &#40;<a class="elsevierStyleCrossRef" href="#fig0005">Figs&#46; 1</a>D&#8211;1F&#41;&#46; Another possibility was to make a perpendicular back-incision from the defect to create a Limberg transposition flap&#46; Finally&#44; if necessary&#44; a second such flap could be created on the other side of the defect &#40;a double Limberg&#41; or an O-to-Z rotation flap could be designed&#46; Such techniques were not usually required in this group&#44; however&#46;</p><p id="par0040" class="elsevierStylePara elsevierViewall">When the minimum achievable side-to-side distance was between 2<span class="elsevierStyleHsp" style=""></span>and 3<span class="elsevierStyleHsp" style=""></span>cm&#44; reconstruction started with 2<span class="elsevierStyleHsp" style=""></span>release incisions on either side of the defect&#46; None of the defects in this category could be closed with a single release incision&#59; 2 such incisions were therefore always made and in many cases achieved sufficient advancement to allow the defect to be closed with 3 independent lines of suture &#40;<a class="elsevierStyleCrossRef" href="#fig0010">Figs&#46; 2</a>A and 2B&#41;&#46; If the defect could not be closed with this approach&#44; however&#44; the release incisions were extended along a curve in the direction of the defect &#40;<a class="elsevierStyleCrossRef" href="#fig0010">Fig&#46; 2</a>C&#41; to create a double rotation flap &#40;<a class="elsevierStyleCrossRef" href="#fig0010">Figs&#46; 2</a>D and 2E&#41;&#46; Other defects in this size group were closed by extending the release incisions with a perpendicular back-incision to create double Limberg flaps&#46;</p><elsevierMultimedia ident="fig0010"></elsevierMultimedia><p id="par0045" class="elsevierStylePara elsevierViewall">When the minimum distance between the sides fell between 3<span class="elsevierStyleHsp" style=""></span>and 4<span class="elsevierStyleHsp" style=""></span>cm&#44; 3<span class="elsevierStyleHsp" style=""></span>release incisions were made around the defect &#40;<a class="elsevierStyleCrossRef" href="#fig0015">Fig&#46; 3</a>A&#41;&#46; None of the defects in this group could be closed with either a single or 2 release incisions&#46; Since it is not possible to switch from 2 to 3 release incisions&#44; 3 of them were appropriately distributed around the defect from the start in all the cases in this group&#46; These incisions facilitated closure of the defect using the recently described Mercedes flap<a class="elsevierStyleCrossRef" href="#bib0075"><span class="elsevierStyleSup">1</span></a> &#40;<a class="elsevierStyleCrossRef" href="#fig0015">Figs&#46; 3</a>B and 3C&#41;&#46; If the wound could not be closed with this approach&#44; all 3 incisions were extended along a curve in the direction of one side of the defect&#46; Three flaps were elevated and the defect was closed with a triple rotation flap technique first described in 1971 by Orticochea&#46;<a class="elsevierStyleCrossRef" href="#bib0080"><span class="elsevierStyleSup">2</span></a> As in the groups described above&#44; the release incisions could also be extended by a perpendicular back-incision to create a triple Limberg flap &#40;<a class="elsevierStyleCrossRef" href="#fig0015">Figs&#46; 3</a>D&#8211;3F&#41;&#46;</p><elsevierMultimedia ident="fig0015"></elsevierMultimedia></span><span id="sec0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0075">Results</span><p id="par0050" class="elsevierStylePara elsevierViewall">The distribution of defect sizes and closure techniques is shown in <a class="elsevierStyleCrossRef" href="#fig0020">Fig&#46; 4</a>&#46; The 119 patients studied &#40;102 men&#44; 17 women&#41; ranged in age from 32 to 93 years&#46; The average age was 71 years&#46; Most of the excised tumors were spindle cell squamous carcinomas &#40;89&#41;&#46; There were also basal cell carcinomas &#40;20&#41;&#44; melanomas &#40;7&#41; merkelomas &#40;2&#41;&#44; and a single angiosarcoma&#46; The patients were followed for an average of 42 months &#40;range&#44; 6&#8211;120 months&#41;&#46;</p><elsevierMultimedia ident="fig0020"></elsevierMultimedia><p id="par0055" class="elsevierStylePara elsevierViewall">Thirty-nine of the 119 patients had small surgical defects &#40;minimum achievable side-to-side distance of less than 1<span class="elsevierStyleHsp" style=""></span>cm&#41;&#46; Thirty-one of these cases were closed with a suture reinforced with a sterile aspiration probe on either side of the wound&#46; Five others that were only partly closed with this type of suture were allowed to complete the process by second-intention healing&#46; Flaps were used in 3<span class="elsevierStyleHsp" style=""></span>other cases &#40;1<span class="elsevierStyleHsp" style=""></span>advancement flap and 2<span class="elsevierStyleHsp" style=""></span>rotation flaps&#41;&#46; Results were excellent in most of the 31 cases closed directly with a reinforced suture&#44; but superinfection of the wound complicated 2<span class="elsevierStyleHsp" style=""></span>cases&#46; Somewhat wider&#44; less cosmetically pleasing scars resulted in the 5<span class="elsevierStyleHsp" style=""></span>cases that were allowed to heal by second intention&#46; Surgery lasted longer in the 3<span class="elsevierStyleHsp" style=""></span>flap reconstructions&#44; and one of these incisions reopened 3<span class="elsevierStyleHsp" style=""></span>days later&#46;</p><p id="par0060" class="elsevierStylePara elsevierViewall">The group of defects with minimum achievable side-to-side distances of 1<span class="elsevierStyleHsp" style=""></span>to 2<span class="elsevierStyleHsp" style=""></span>cm comprised 33<span class="elsevierStyleHsp" style=""></span>cases&#46; A single release incision started the process in 22<span class="elsevierStyleHsp" style=""></span>of these cases and closure was completed without a flap in 13<span class="elsevierStyleHsp" style=""></span>of them&#46; The release incision was extended to allow closure with a rotation flap in the 9<span class="elsevierStyleHsp" style=""></span>remaining cases in this group&#44; and that technique provided successful reconstruction in 6 of them&#46; In 2 cases the incision was extended to create a Limberg transposition flap&#44; and in the last of the 9<span class="elsevierStyleHsp" style=""></span>cases a second contralateral rotation flap was required to close the defect with a double O-to-Z rotation flap&#46; No initial release incision was made in 11<span class="elsevierStyleHsp" style=""></span>cases in this 33-patient group&#46; Instead&#44; a rotation flap was immediately chosen for 8 of the 11&#44; and a Limberg transposition flap was used for the other 3&#46; Good cosmetic results were seen in short- and long-term follow-up visits with these patients&#44; except for slight dehiscence in a reconstruction started with a single release incision and in another reconstructed directly with a Limberg flap&#46;</p><p id="par0065" class="elsevierStylePara elsevierViewall">There were 21<span class="elsevierStyleHsp" style=""></span>patients in the group with defects with minimum side-to-side distances of 2<span class="elsevierStyleHsp" style=""></span>to 3<span class="elsevierStyleHsp" style=""></span>cm&#46; Two release incisions were made in 14 of them and were sufficient for closure in 6&#46; In a few cases a single release incision was initially tried but was never sufficient for closure&#59; therefore&#44; a second was made&#46; In another 6<span class="elsevierStyleHsp" style=""></span>in the group of 14<span class="elsevierStyleHsp" style=""></span>patients for whom the 2<span class="elsevierStyleHsp" style=""></span>release incisions were insufficient&#44; the incisions were extended to create 2<span class="elsevierStyleHsp" style=""></span>O-to-Z rotation flaps&#46; The 2<span class="elsevierStyleHsp" style=""></span>remaining patients in the group required extension of the incisions to create 2<span class="elsevierStyleHsp" style=""></span>transposition flaps &#40;1<span class="elsevierStyleHsp" style=""></span>Limberg-type flap and 1<span class="elsevierStyleHsp" style=""></span>bilobed flap&#41;&#46; In the 7<span class="elsevierStyleHsp" style=""></span>remaining cases in this group of 21&#44; a double rotation flap &#40;5<span class="elsevierStyleHsp" style=""></span>cases&#41; or a transposition flap &#40;2<span class="elsevierStyleHsp" style=""></span>cases&#41; was designed directly&#46; No differences were observed in outcomes during follow-up&#44; regardless of whether or not release incisions were made &#40;ie&#44; whether flaps were initially designed or the result of extending the release incisions&#41;&#46; The sutures reopened in only 2 cases repaired by starting with release incisions&#46; A single case of superinfection occurred in a defect closed with a double Limberg flap created by extending the release incisions&#46;</p><p id="par0070" class="elsevierStylePara elsevierViewall">Fourteen patients had defects that measured 3<span class="elsevierStyleHsp" style=""></span>to 4<span class="elsevierStyleHsp" style=""></span>cm from side to side&#46; None of the 14 could be closed with either 1 or 2 release incisions&#46; In 7 of the 14 cases&#44; 3 release incisions were made directly&#44; and they allowed for primary closure of the defect with a Mercedes flap in 3 of them&#46; In the other 4 cases&#44; the release incisions were extended back to the defect to create triple rotation flaps in 2<span class="elsevierStyleHsp" style=""></span>and Limberg transposition rotation flaps in 2&#46; The remaining 7<span class="elsevierStyleHsp" style=""></span>defects were repaired directly with triple Limberg flaps &#40;6<span class="elsevierStyleHsp" style=""></span>cases&#41; or a triple rotation flap &#40;1<span class="elsevierStyleHsp" style=""></span>case&#41;&#46; No differences in outcomes were observed on follow-up&#44; although 1<span class="elsevierStyleHsp" style=""></span>Mercedes flap and 2<span class="elsevierStyleHsp" style=""></span>of the direct Limberg flaps opened up&#46;</p><p id="par0075" class="elsevierStylePara elsevierViewall">Twelve patients had surgical defects measuring more than 4<span class="elsevierStyleHsp" style=""></span>cm even after the sides were pulled together&#46; Reconstruction started with 3 release incisions in 3 of the 12&#44; but as primary closure could not be achieved&#44; triple flaps were designed&#46; Seven cases required skin grafts&#46; Two were left for second-intention healing&#46; Closure with a triple rotation flap was attempted in 2<span class="elsevierStyleHsp" style=""></span>cases&#46; One of them closed partially and a graft was then provided to complete the closure&#46; The twelfth case was reconstructed with a directly designed triple Limberg flap&#46; Follow-up records showed that second-intention healing took more than 6<span class="elsevierStyleHsp" style=""></span>weeks&#46; The outcomes in the cases requiring grafts were good&#44; although partial necrosis developed in 1<span class="elsevierStyleHsp" style=""></span>of the 7<span class="elsevierStyleHsp" style=""></span>cases&#44; and the cosmetic outcome was not ideal in some&#46; Dehiscence occurred in 2<span class="elsevierStyleHsp" style=""></span>of the 3<span class="elsevierStyleHsp" style=""></span>flap reconstructions&#46;</p><p id="par0080" class="elsevierStylePara elsevierViewall">Overall&#44; 13 of the 119 patients &#40;10&#46;92&#37;&#41; experienced some type of complication or poor cosmetic outcome&#44; results that were more frequent in patients with large surgical defects&#46; However&#44; frequency bore no relation to the type of reconstruction technique chosen&#46;</p></span><span id="sec0020" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0080">Discussion</span><p id="par0085" class="elsevierStylePara elsevierViewall">Guidelines and review articles advise on the best reconstruction approach to use in difficult areas on the face&#44;<a class="elsevierStyleCrossRefs" href="#bib0085"><span class="elsevierStyleSup">3&#44;4</span></a> but the closure of surgical defects on the scalp is particularly problematic because of skin tension and poor elasticity&#46; Most clinical guidelines and decision trees use the area of the defect as the basis for choosing the most appropriate technique&#46;<a class="elsevierStyleCrossRefs" href="#bib0095"><span class="elsevierStyleSup">5&#8211;9</span></a> However&#44; this criterion does not take into consideration interindividual variation in skin elasticity or other patient factors such as the zone under the scalp that is affected or the effects of prior treatments &#40;for example&#44; fibrosis after radiotherapy or scaring from previous sutures&#41;&#46; To remedy this problem&#44; this study proposes a new concept&#44; the minimum side-to-side distance when the skin around the defect is drawn together manually&#46; This minimum manually achievable distance between sides reflects a combination of the diameter of the defect and the elasticity of the tissues around it and thus offers an objective criterion for guiding choice of reconstructive technique&#46; To use this approach&#44; the surgeon beginning reconstruction of the defect created by excising a scalp lesion&#44; must first draw the sides of the defect as close together as possible and measure the minimum distance&#46; This maneuver&#44; which surgeons often do unconsciously&#44; should be expressly attended to and measured precisely if it is to provide information on which to base the choice of reconstructive technique&#46;</p><p id="par0090" class="elsevierStylePara elsevierViewall">Another innovative aspect of this approach is the initial employment of release incisions as the first reconstructive step&#46; These extra incisions increase the area that can be advanced&#46; The tissue freed in this way is sufficient to close most defects&#46;</p><p id="par0095" class="elsevierStylePara elsevierViewall">Yet another contribution this approach makes is to facilitate flap design by extending the release incisions in the event that they are insufficient for defect closure&#46; Because these incisions can be transformed&#44; a strategic sequence emerges that starts by trying the simplest effective technique and then adapting it according to individual circumstances&#46;</p><p id="par0100" class="elsevierStylePara elsevierViewall">This retrospective case series shows that large defects&#44; of a minimum distance of more than 4<span class="elsevierStyleHsp" style=""></span>cm&#44; can be closed by either second-intention healing or total skin grafts&#46; Release incisions did not achieve closure of any of these defects&#44; and flap closure&#160;&#8212;whether initially planned or created by extending release incisions&#160;&#8212;was associated with a higher rate of complications&#46; Other options for closing large defects include galeal incisions to facilitate skin displacement&#44; flaps in combination with Burow grafts&#44; tissue expansion&#44;<a class="elsevierStyleCrossRef" href="#bib0120"><span class="elsevierStyleSup">10</span></a> latissimus dorsi pediculated flaps&#44;<a class="elsevierStyleCrossRef" href="#bib0125"><span class="elsevierStyleSup">11</span></a> free flaps&#44;<a class="elsevierStyleCrossRef" href="#bib0130"><span class="elsevierStyleSup">12</span></a> or dermal regeneration systems&#46;<a class="elsevierStyleCrossRef" href="#bib0135"><span class="elsevierStyleSup">13</span></a></p><p id="par0105" class="elsevierStylePara elsevierViewall">The reconstruction decision tree described here&#44; using the minimum manually achievable distance between the sides of a defect as the starting point&#44; is termed the 1&#8211;2&#8211;3 rule for its mnemonic value&#46; To reconstruct defects with a minimum distance between 1<span class="elsevierStyleHsp" style=""></span>and 2<span class="elsevierStyleHsp" style=""></span>cm&#44; start with 1<span class="elsevierStyleHsp" style=""></span>release incision&#59; for defects between 2<span class="elsevierStyleHsp" style=""></span>and 3<span class="elsevierStyleHsp" style=""></span>cm&#44; start with 2<span class="elsevierStyleHsp" style=""></span>incisions&#59; and for those between 3<span class="elsevierStyleHsp" style=""></span>and 4<span class="elsevierStyleHsp" style=""></span>cm&#44; start with 3<span class="elsevierStyleHsp" style=""></span>incisions&#46; If closure cannot be accomplished with the recommended number of release incisions&#44; they can be extended to design rotation or transposition flaps &#40;<a class="elsevierStyleCrossRef" href="#fig0025">Fig&#46; 5</a>&#41;&#46;</p><elsevierMultimedia ident="fig0025"></elsevierMultimedia><p id="par0110" class="elsevierStylePara elsevierViewall">Sixty-eight cases in this series involved mid-sized defects with minimum manually achievable distances between 1<span class="elsevierStyleHsp" style=""></span>and 4<span class="elsevierStyleHsp" style=""></span>cm&#46; Closure was achieved by means of the release incisions in 22 of the 43 cases &#40;51&#37;&#41; in which the reconstruction process started with them&#46; Thus&#44; over half the patients&#8217; defects could be fully closed by using the simplest process&#44; which takes advantage of the mobility afforded by such incisions without resort to flaps&#46;</p><p id="par0115" class="elsevierStylePara elsevierViewall">The proposed stepped and adaptable 1&#8211;2&#8211;3 rule follows a logical sequence that starts by attempting closure with a direct suture&#46; If closure is not possible&#44; the surgeon passes on to the next simplest option&#160;&#8212;a reinforced suture&#46; The next step in the sequence is a release incision&#44; followed if necessary by extending the incision to design a rotation or transposition flap&#46; A fourth option is the design of a contralateral rotation or transposition flap to facilitate movement of a large area of surrounding tissue to close the defect&#46; This stepped approach therefore offers many alternatives incrementally while still ensuring that the simplest possible technique appropriate for each defect will be the one that is used&#46; In contrast&#44; if a complex flap is designed and begun from the start of reconstruction&#44; closure may still be impeded but without the possibility of incrementally adding alternatives&#46;</p><p id="par0120" class="elsevierStylePara elsevierViewall">Naturally&#44; this 1&#8211;2&#8211;3 rule must be adapted to individual cases&#44; according to the patient&#39;s general condition and the surgeon&#39;s preferences&#46; For certain individuals and defects with minimum side-to-side distances between 1<span class="elsevierStyleHsp" style=""></span>and 4<span class="elsevierStyleHsp" style=""></span>cm&#44; skin grafts covering the whole defect or second-intention healing may be good options&#46; However&#44; grafts usually give inferior cosmetic results and are associated with greater risk of necrosis&#46; Second-intention healing&#44; on the other hand&#44; although simple and faster to prepare&#44; requires a much longer period of waiting for scar tissue to form&#44; placing a greater burden on the patient while still giving only modest cosmetic results at the end&#46;</p><p id="par0125" class="elsevierStylePara elsevierViewall">The complication rates in this case series were similar to those reported in another series&#46;<a class="elsevierStyleCrossRef" href="#bib0140"><span class="elsevierStyleSup">14</span></a> Complications were more common in patients with large defects&#44; but no influence of reconstructive technique could be identified&#46; Flaps made by extending the release incisions yielded cosmetic and functional results that were similar to the flaps designed from the start of the process&#46; This observation supports the approach of beginning with release incisions to attempt to close the defect by that means alone and later extending incisions to create flaps only if necessary&#46;</p></span><span id="sec0025" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0085">Limitations</span><p id="par0130" class="elsevierStylePara elsevierViewall">This study is affected by the limitations intrinsic to any retrospective design&#46; The protocol described&#44; starting with release incisions&#44; was not applied to all the scalp defects resolved during the period of the study&#46; Of the 68 patients with defects measuring 1<span class="elsevierStyleHsp" style=""></span>to 4<span class="elsevierStyleHsp" style=""></span>cm&#44; reconstruction started with release incisions in 43&#46; Reconstruction flaps were planned initially for the other patients before the protocol described by the 1&#8211;2&#8211;3 rule was introduced&#46; In addition&#44; the number of patients with large defects &#40;minimum manually achievable distances of 4<span class="elsevierStyleHsp" style=""></span>cm from side to side&#41; was small in comparison with the numbers in other groups&#46; Therefore&#44; it is impossible to draw conclusions about other more complex reconstruction techniques for defects that are large or involve the bone&#46; Initiating reconstruction with release incisions is therefore appropriate only for defect sizes with minimum manually achievable distances of 1<span class="elsevierStyleHsp" style=""></span> to 4<span class="elsevierStyleHsp" style=""></span>cm between sides&#46;</p></span><span id="sec0030" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0090">Conclusions</span><p id="par0135" class="elsevierStylePara elsevierViewall">This stepped approach to choosing the simplest effective technique for closing scalp defects relies on first observing the minimum manually achievable distance between the sides of a defect&#46; The 1&#8211;2&#8211;3 rule indicates the number of release incisions that mark the starting point in the reconstruction process&#44; according to the minimum distance measured&#46; The incisions can be extended to design flaps if necessary&#46;</p></span><span id="sec0035" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0095">Conflicts of Interest</span><p id="par0140" class="elsevierStylePara elsevierViewall">The author declares that he has no conflicts of interest&#46;</p></span></span>"
    "textoCompletoSecciones" => array:1 [
      "secciones" => array:12 [
        0 => array:3 [
          "identificador" => "xres1216314"
          "titulo" => "Abstract"
          "secciones" => array:4 [
            0 => array:2 [
              "identificador" => "abst0005"
              "titulo" => "Background and objective"
            ]
            1 => array:2 [
              "identificador" => "abst0010"
              "titulo" => "Material and methods"
            ]
            2 => array:2 [
              "identificador" => "abst0015"
              "titulo" => "Results"
            ]
            3 => array:2 [
              "identificador" => "abst0020"
              "titulo" => "Conclusions"
            ]
          ]
        ]
        1 => array:2 [
          "identificador" => "xpalclavsec1131865"
          "titulo" => "Keywords"
        ]
        2 => array:3 [
          "identificador" => "xres1216313"
          "titulo" => "Resumen"
          "secciones" => array:4 [
            0 => array:2 [
              "identificador" => "abst0025"
              "titulo" => "Antecedentes y objetivos"
            ]
            1 => array:2 [
              "identificador" => "abst0030"
              "titulo" => "Materiales y m&#233;todos"
            ]
            2 => array:2 [
              "identificador" => "abst0035"
              "titulo" => "Resultados"
            ]
            3 => array:2 [
              "identificador" => "abst0040"
              "titulo" => "Conclusiones"
            ]
          ]
        ]
        3 => array:2 [
          "identificador" => "xpalclavsec1131864"
          "titulo" => "Palabras clave"
        ]
        4 => array:2 [
          "identificador" => "sec0005"
          "titulo" => "Introduction"
        ]
        5 => array:2 [
          "identificador" => "sec0010"
          "titulo" => "Materials and Methods"
        ]
        6 => array:2 [
          "identificador" => "sec0015"
          "titulo" => "Results"
        ]
        7 => array:2 [
          "identificador" => "sec0020"
          "titulo" => "Discussion"
        ]
        8 => array:2 [
          "identificador" => "sec0025"
          "titulo" => "Limitations"
        ]
        9 => array:2 [
          "identificador" => "sec0030"
          "titulo" => "Conclusions"
        ]
        10 => array:2 [
          "identificador" => "sec0035"
          "titulo" => "Conflicts of Interest"
        ]
        11 => array:1 [
          "titulo" => "References"
        ]
      ]
    ]
    "pdfFichero" => "main.pdf"
    "tienePdf" => true
    "fechaRecibido" => "2018-11-18"
    "fechaAceptado" => "2019-01-24"
    "PalabrasClave" => array:2 [
      "en" => array:1 [
        0 => array:4 [
          "clase" => "keyword"
          "titulo" => "Keywords"
          "identificador" => "xpalclavsec1131865"
          "palabras" => array:3 [
            0 => "Scalp surgery"
            1 => "Algorithm"
            2 => "Flaps"
          ]
        ]
      ]
      "es" => array:1 [
        0 => array:4 [
          "clase" => "keyword"
          "titulo" => "Palabras clave"
          "identificador" => "xpalclavsec1131864"
          "palabras" => array:3 [
            0 => "Cirug&#237;a cuero cabelludo"
            1 => "Algoritmo"
            2 => "Colgajos"
          ]
        ]
      ]
    ]
    "tieneResumen" => true
    "resumen" => array:2 [
      "en" => array:3 [
        "titulo" => "Abstract"
        "resumen" => "<span id="abst0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0010">Background and objective</span><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Excision of cutaneous scalp tumors results in surgical defects that are difficult to repair because of poor distensibility in this area of the body&#46; The main aim of this study was to develop a structured algorithm to help choose the best technique for reconstructing scalp defects&#46;</p></span> <span id="abst0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0015">Material and methods</span><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Retrospective study of patients who required surgical reconstruction following excision of a cutaneous scalp tumor&#46; We excluded patients with defects that could be closed by simple direct suture and defects for which it was initially decided to use a skin graft or healing by secondary intention&#46; The defects were classified into 5 groups according to the minimum distance between edges&#46; The different reconstruction techniques used were evaluated in each group&#46; The outcomes analyzed were complete defect closure&#44; intraoperative and postoperative complications&#44; and final aesthetic result&#46;</p></span> <span id="abst0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0020">Results</span><p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">We included 119 patients &#40;102 men and 17 women&#41; with a mean age of 71 years &#40;range&#44; 32&#8211;93 years&#41;&#46; Mean follow-up was 42 months &#40;range&#44; 6&#8211;120 months&#41;&#46; Sixty-eight patients had a moderate-sized defect with a distance between edges of 1 to 4<span class="elsevierStyleHsp" style=""></span>cm&#46; Reconstructions started with relaxation incisions in 43 defects and resulted in the successful closure of 22 of them&#46; Defects with a distance of 1 to 2<span class="elsevierStyleHsp" style=""></span>cm required a single relaxation incision&#46; Two incisions were required for defects with a distance of 2 to 3<span class="elsevierStyleHsp" style=""></span>cm&#44; while 3 incisions were required for those with a distance of 3 to 4<span class="elsevierStyleHsp" style=""></span>cm&#46; In the 21 cases in which relaxation incisions were insufficient to close the defect&#44; the incisions were extended to mobilize the flap to achieve closure&#46; Relaxation incisions alone were insufficient for closing defects with a distance greater than 4<span class="elsevierStyleHsp" style=""></span>cm&#46;</p></span> <span id="abst0020" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0025">Conclusions</span><p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">The 1-2-3 rule can help in choosing the best reconstruction technique for moderate-sized defects based on the principle that 1&#44; 2&#44; or 3 initial relaxation incisions are needed depending on the minimum distance between edges &#40;1-2<span class="elsevierStyleHsp" style=""></span>cm&#44; 2-3<span class="elsevierStyleHsp" style=""></span>cm&#44; or 3-4<span class="elsevierStyleHsp" style=""></span>cm&#41;&#46; In all cases&#44; incision extension to mobilize the corresponding flaps remains an option&#46;</p></span>"
        "secciones" => array:4 [
          0 => array:2 [
            "identificador" => "abst0005"
            "titulo" => "Background and objective"
          ]
          1 => array:2 [
            "identificador" => "abst0010"
            "titulo" => "Material and methods"
          ]
          2 => array:2 [
            "identificador" => "abst0015"
            "titulo" => "Results"
          ]
          3 => array:2 [
            "identificador" => "abst0020"
            "titulo" => "Conclusions"
          ]
        ]
      ]
      "es" => array:3 [
        "titulo" => "Resumen"
        "resumen" => "<span id="abst0025" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0035">Antecedentes y objetivos</span><p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">La extirpaci&#243;n quir&#250;rgica de tumores cut&#225;neos de cuero cabelludo crea defectos dif&#237;ciles de reparar por la poca distensibilidad de la zona&#46; El objetivo principal de este trabajo es conseguir un algoritmo estructurado que permita la elecci&#243;n de la mejor t&#233;cnica reconstructiva para el cierre de los defectos quir&#250;rgicos de cuero cabelludo&#46;</p></span> <span id="abst0030" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0040">Materiales y m&#233;todos</span><p id="spar0030" class="elsevierStyleSimplePara elsevierViewall">Estudio retrospectivo de 119 pacientes que requirieron la extirpaci&#243;n quir&#250;rgica de tumores de cuero cabelludo con posterior reconstrucci&#243;n quir&#250;rgica para el cierre del defecto&#46; Se excluyeron los pacientes con defectos que pudieron ser cerrados mediante sutura directa simple&#44; as&#237; como en los que desde el principio se decidi&#243; emplear injertos cut&#225;neos o se dejaron cerrar por segunda intenci&#243;n&#46; Los defectos se clasificaron en 5 grupos seg&#250;n la distancia m&#237;nima de aproximaci&#243;n de los bordes y se evaluaron en cada grupo las diferentes opciones de reconstrucci&#243;n quir&#250;rgica&#46; Se tuvieron en cuenta como objetivos finales el cierre completo del defecto&#44; las complicaciones intra- y postoperatorias&#44; as&#237; como el resultado est&#233;tico final&#46;</p></span> <span id="abst0035" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0045">Resultados</span><p id="spar0035" class="elsevierStyleSimplePara elsevierViewall">Se incluyeron 119 pacientes &#40;102 varones y 17 mujeres&#41;&#59; edad media 71 a&#241;os &#40;rango&#44; 32-93 a&#241;os&#41;&#46; El seguimiento medio fue de 42 meses &#40;rango&#44; 6-120 meses&#41;&#46; De los 119 pacientes&#44; 68 ten&#237;an defectos de mediano tama&#241;o con una distancia de aproximaci&#243;n entre 1 y 4<span class="elsevierStyleHsp" style=""></span>cm&#46; En 43 de ellos se inici&#243; la reconstrucci&#243;n mediante incisiones de descarga que permitieron el cierre del defecto en 22 casos&#46; Los defectos con distancias de 1 a 2<span class="elsevierStyleHsp" style=""></span>cm necesitaron una sola incisi&#243;n de descarga&#46; Los comprendidos entre 2 y 3<span class="elsevierStyleHsp" style=""></span>cm&#44; 2 incisiones y de 3 a 4<span class="elsevierStyleHsp" style=""></span>cm&#44; 3 incisiones&#46; En los 21 casos que no cerraron a trav&#233;s de las incisiones de descarga&#44; se ampliaron estas incisiones a sus correspondientes colgajos para conseguir el cierre&#46; Ninguno de los defectos mayores de 4<span class="elsevierStyleHsp" style=""></span>cm cerr&#243; solo con las incisiones de descarga&#46;</p></span> <span id="abst0040" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0050">Conclusiones</span><p id="spar0040" class="elsevierStyleSimplePara elsevierViewall">La regla&#171;1-2-3&#187; permite elegir la mejor t&#233;cnica reconstructiva para defectos de mediano tama&#241;o realizando inicialmente 1&#44; 2 o 3 incisiones de descarga seg&#250;n sea la distancia de aproximaci&#243;n de los bordes del defecto entre 1-2<span class="elsevierStyleHsp" style=""></span>cm&#44; entre 2-3<span class="elsevierStyleHsp" style=""></span>cm o entre 3-4<span class="elsevierStyleHsp" style=""></span>cm respectivamente&#44; con la opci&#243;n de ampliar a los colgajos correspondientes si fuera necesario&#46;</p></span>"
        "secciones" => array:4 [
          0 => array:2 [
            "identificador" => "abst0025"
            "titulo" => "Antecedentes y objetivos"
          ]
          1 => array:2 [
            "identificador" => "abst0030"
            "titulo" => "Materiales y m&#233;todos"
          ]
          2 => array:2 [
            "identificador" => "abst0035"
            "titulo" => "Resultados"
          ]
          3 => array:2 [
            "identificador" => "abst0040"
            "titulo" => "Conclusiones"
          ]
        ]
      ]
    ]
    "NotaPie" => array:1 [
      0 => array:2 [
        "etiqueta" => "&#9734;"
        "nota" => "<p class="elsevierStyleNotepara" id="npar0005">Please cite this article as&#58; Russo F&#46; Regla &#171;1-2-3&#187; para la reconstrucci&#243;n de defectos de mediano tama&#241;o del cuero cabelludo&#46; Actas Dermosifiliogr&#46; 2019&#59;110&#58;474&#8211;481&#46;</p>"
      ]
    ]
    "multimedia" => array:5 [
      0 => array:7 [
        "identificador" => "fig0005"
        "etiqueta" => "Figure 1"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr1.jpeg"
            "Alto" => 2240
            "Ancho" => 1733
            "Tamanyo" => 618223
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0045" class="elsevierStyleSimplePara elsevierViewall">Reconstruction of defects with a minimum side-to-side distance less than 2<span class="elsevierStyleHsp" style=""></span>cm after the skin was drawn together manually&#46; A&#44; Measuring the minimum achievable distance between sides&#46; B&#44; A probe-reinforced suture is recommended for distances less than 1<span class="elsevierStyleHsp" style=""></span>cm&#46; C&#44; Defects measuring between 1<span class="elsevierStyleHsp" style=""></span>and 2<span class="elsevierStyleHsp" style=""></span>cm may require a release incision&#46; D&#8211;F&#44; If closure is still not possible&#44; a rotation flap can be used&#46;</p>"
        ]
      ]
      1 => array:7 [
        "identificador" => "fig0010"
        "etiqueta" => "Figure 2"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr2.jpeg"
            "Alto" => 2304
            "Ancho" => 1733
            "Tamanyo" => 452744
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0055" class="elsevierStyleSimplePara elsevierViewall">Reconstruction of defects with a minimum side-to-side distance of 2<span class="elsevierStyleHsp" style=""></span>to 3<span class="elsevierStyleHsp" style=""></span>cm after the skin was drawn together manually&#46;</p> <p id="spar0060" class="elsevierStyleSimplePara elsevierViewall">A&#44; Begin the process of closing these defects by making 2<span class="elsevierStyleHsp" style=""></span>release incisions&#46; B&#44; After elevating the tissue&#44; close with sutures&#46; C&#8211;D&#44; If that approach fails&#44; design a double O-to-Z rotation flap&#46; E&#44; Close&#46;</p>"
        ]
      ]
      2 => array:7 [
        "identificador" => "fig0015"
        "etiqueta" => "Figure 3"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr3.jpeg"
            "Alto" => 2620
            "Ancho" => 1733
            "Tamanyo" => 888662
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0065" class="elsevierStyleSimplePara elsevierViewall">Reconstruction of defects with a minimum side-to-side distance of 3<span class="elsevierStyleHsp" style=""></span>to 4<span class="elsevierStyleHsp" style=""></span>cm after the skin was drawn together manually&#46; A&#44; Begin the process of closing these defects by making 3<span class="elsevierStyleHsp" style=""></span>release incisions&#46; B&#44; Draw the skin together and secure with a single suture&#46; C&#44; Close the release incisions with a Mercedes flap&#46; D&#8211;E&#44; If a Mercedes flap cannot close the defect&#44; prepare a triple Limberg flap&#46; F&#44; Close&#46;</p>"
        ]
      ]
      3 => array:7 [
        "identificador" => "fig0020"
        "etiqueta" => "Figure 4"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr4.jpeg"
            "Alto" => 1607
            "Ancho" => 3125
            "Tamanyo" => 255274
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0070" class="elsevierStyleSimplePara elsevierViewall">Surgical defect reconstruction techniques used in the 119<span class="elsevierStyleHsp" style=""></span>patients in the series&#46;</p>"
        ]
      ]
      4 => array:7 [
        "identificador" => "fig0025"
        "etiqueta" => "Figure 5"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr5.jpeg"
            "Alto" => 1275
            "Ancho" => 2500
            "Tamanyo" => 195527
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0075" class="elsevierStyleSimplePara elsevierViewall">The 1&#8211;2&#8211;3 rule for reconstructing scalp defects&#46;</p> <p id="spar0080" class="elsevierStyleSimplePara elsevierViewall">Reconstruction of defects with a minimum side-to-side distance of 1 to 2<span class="elsevierStyleHsp" style=""></span>cm starts with a single release incision that can be extended to create a rotation or transposition flap if necessary&#46; Reconstruction of defects with a minimum side-to-side distance of 2 to 3<span class="elsevierStyleHsp" style=""></span>cm starts with 2 release incisions&#44; which can be extended to create double rotation or transposition flaps&#46; Reconstruction of defects with a minimum side-to-side distance of 3 to 4<span class="elsevierStyleHsp" style=""></span>cm starts with 3 release incisions&#44; which can be extended to provide triple rotation or transposition flaps if necessary&#46;</p>"
        ]
      ]
    ]
    "bibliografia" => array:2 [
      "titulo" => "References"
      "seccion" => array:1 [
        0 => array:2 [
          "identificador" => "bibs0015"
          "bibliografiaReferencia" => array:14 [
            0 => array:3 [
              "identificador" => "bib0075"
              "etiqueta" => "1"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Mercedes flap with releasing incisions for scalp defects"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "F&#46; Russo"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1097/SAP.0000000000001053"
                      "Revista" => array:6 [
                        "tituloSerie" => "Ann Plast Surg&#46;"
                        "fecha" => "2017"
                        "volumen" => "79"
                        "paginaInicial" => "149"
                        "paginaFinal" => "155"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/28328636"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            1 => array:3 [
              "identificador" => "bib0080"
              "etiqueta" => "2"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "New three-flap reconstruction technique"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "M&#46; Orticochea"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:4 [
                        "tituloSerie" => "Br J Plast Surg"
                        "fecha" => "1971"
                        "volumen" => "24"
                        "paginaInicial" => "184"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            2 => array:3 [
              "identificador" => "bib0085"
              "etiqueta" => "3"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Reconstruction of facial structures"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "S&#46;R&#46; Baker"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Libro" => array:7 [
                        "edicion" => "2nd ed"
                        "titulo" => "Local flaps in facial reconstruction&#46;"
                        "fecha" => "2007"
                        "paginaInicial" => "385"
                        "paginaFinal" => "637"
                        "editorial" => "Mosby &#40;Elsevier&#41;"
                        "editorialLocalizacion" => "Philadelphia"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            3 => array:3 [
              "identificador" => "bib0090"
              "etiqueta" => "4"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Reconstruction techniques of choice for the facial cosmetic units"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "F&#46; Russo"
                            1 => "M&#46; Linares"
                            2 => "M&#46;E&#46; Iglesias"
                            3 => "J&#46;L&#46; Mart&#237;nez-Amo"
                            4 => "F&#46; Cabo"
                            5 => "J&#46; Tercedor"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Actas Dermosifiliogr&#46;"
                        "fecha" => "2017"
                        "volumen" => "108"
                        "paginaInicial" => "729"
                        "paginaFinal" => "737"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            4 => array:3 [
              "identificador" => "bib0095"
              "etiqueta" => "5"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "An algorithm for oncologic scalp reconstruction"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "N&#46; Iblher"
                            1 => "M&#46;C&#46; Ziegler"
                            2 => "V&#46; Penna"
                            3 => "S&#46;U&#46; Eisenhardt"
                            4 => "G&#46;B&#46; Stark"
                            5 => "H&#46; Bannasch"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1097/PRS.0b013e3181e09515"
                      "Revista" => array:6 [
                        "tituloSerie" => "Plast Reconstr Surg"
                        "fecha" => "2010"
                        "volumen" => "126"
                        "paginaInicial" => "450"
                        "paginaFinal" => "459"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/20679829"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            5 => array:3 [
              "identificador" => "bib0100"
              "etiqueta" => "6"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Can we put a simplified algorithm for reconstruction of large scalp defects following tumor resection&#63;"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "A&#46; Denewer"
                            1 => "A&#46; Khater"
                            2 => "O&#46; Farouk"
                            3 => "M&#46; Hegazy"
                            4 => "M&#46; Mosbah"
                            5 => "M&#46; Hafez"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:4 [
                        "tituloSerie" => "World J Surg Oncol"
                        "fecha" => "2011"
                        "volumen" => "9"
                        "paginaInicial" => "129"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            6 => array:3 [
              "identificador" => "bib0105"
              "etiqueta" => "7"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Reconstruction of acquired scalp defects&#58; An algorithmic approach"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "J&#46;E&#46; Leedy"
                            1 => "J&#46;E&#46; Janis"
                            2 => "R&#46;J&#46; Rohrich"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Plast Reconstr Surg&#46;"
                        "fecha" => "2005"
                        "volumen" => "116"
                        "paginaInicial" => "54e"
                        "paginaFinal" => "72e"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            7 => array:3 [
              "identificador" => "bib0110"
              "etiqueta" => "8"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Current options in head and neck reconstruction"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "K&#46;A&#46; Hurvitz"
                            1 => "M&#46; Kobayashi"
                            2 => "G&#46;R&#46; Evans"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Plast Reconstr Surg&#46;"
                        "fecha" => "2006"
                        "volumen" => "118"
                        "paginaInicial" => "122e"
                        "paginaFinal" => "133e"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            8 => array:3 [
              "identificador" => "bib0115"
              "etiqueta" => "9"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Scalp reconstruction&#58; A 15-year experience"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "M&#46;I&#46; Newman"
                            1 => "M&#46;M&#46; Hanasono"
                            2 => "J&#46;J&#46; Disa"
                            3 => "P&#46;G&#46; Cordeiro"
                            4 => "B&#46;J&#46; Mehrara"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Ann Plast Surg"
                        "fecha" => "2004"
                        "volumen" => "52"
                        "paginaInicial" => "501"
                        "paginaFinal" => "506"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15096938"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            9 => array:3 [
              "identificador" => "bib0120"
              "etiqueta" => "10"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Scalp stretching with a tissue expander for closure of scalp defects"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "R&#46;E&#46;A&#46; Nordstrom"
                            1 => "J&#46;W&#46; Devine"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Plast Reconstr Surg"
                        "fecha" => "1985"
                        "volumen" => "75"
                        "paginaInicial" => "578"
                        "paginaFinal" => "581"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            10 => array:3 [
              "identificador" => "bib0125"
              "etiqueta" => "11"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Management of large scalp defects with local pedicle flaps"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "M&#46;A&#46; Lesavoy"
                            1 => "T&#46;J&#46; Dubrow"
                            2 => "R&#46;J&#46; Schwartz"
                            3 => "P&#46;A&#46; Wackym"
                            4 => "D&#46;M&#46; Eisenhauer"
                            5 => "M&#46; McGuire"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Plast Reconstr Surg"
                        "fecha" => "1993"
                        "volumen" => "91"
                        "paginaInicial" => "783"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8460180"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            11 => array:3 [
              "identificador" => "bib0130"
              "etiqueta" => "12"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Reconstruction of scalp defects with free flaps in 30 cases"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "B&#46;S&#46; Lutz"
                            1 => "F&#46;C&#46; Wei"
                            2 => "H&#46;C&#46; Chen"
                            3 => "C&#46;H&#46; Lin"
                            4 => "C&#46;Y&#46; Wei"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Br J Plast Surg&#46;"
                        "fecha" => "1998"
                        "volumen" => "51"
                        "paginaInicial" => "186"
                        "paginaFinal" => "190"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            12 => array:3 [
              "identificador" => "bib0135"
              "etiqueta" => "13"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Use of dermal regeneration template &#40;Integra&#41; for reconstruction of full-thickness complex oncologic scalp defects"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "M&#46;A&#46; Khan"
                            1 => "S&#46;N&#46; Ali"
                            2 => "M&#46; Farid"
                            3 => "M&#46; Pancholi"
                            4 => "S&#46; Rayatt"
                            5 => "L&#46;H&#46; Yap"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "J Craniofac Surg"
                        "fecha" => "2010"
                        "volumen" => "21"
                        "paginaInicial" => "905"
                        "paginaFinal" => "909"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            13 => array:3 [
              "identificador" => "bib0140"
              "etiqueta" => "14"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Complications after oncologic scalp reconstruction&#58; A 139-patient series and treatment algorithm"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "J&#46;R&#46; Janus"
                            1 => "B&#46;W&#46; Peck"
                            2 => "N&#46;M&#46; Tombers"
                            3 => "D&#46;L&#46; Price"
                            4 => "E&#46;J&#46; Moore"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Laryngoscope&#46;"
                        "fecha" => "2015"
                        "volumen" => "125"
                        "paginaInicial" => "582"
                        "paginaFinal" => "588"
                      ]
                    ]
                  ]
                ]
              ]
            ]
          ]
        ]
      ]
    ]
  ]
  "idiomaDefecto" => "en"
  "url" => "/15782190/0000011000000006/v1_201907040838/S1578219019301490/v1_201907040838/en/main.assets"
  "Apartado" => array:4 [
    "identificador" => "6155"
    "tipo" => "SECCION"
    "en" => array:2 [
      "titulo" => "Original Articles"
      "idiomaDefecto" => true
    ]
    "idiomaDefecto" => "en"
  ]
  "PDF" => "https://static.elsevier.es/multimedia/15782190/0000011000000006/v1_201907040838/S1578219019301490/v1_201907040838/en/main.pdf?idApp=UINPBA000044&text.app=https://actasdermo.org/"
  "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219019301490?idApp=UINPBA000044"
]
Información del artículo
ISSN: 15782190
Idioma original: Inglés
Datos actualizados diariamente
año/Mes Html Pdf Total
2024 Noviembre 20 9 29
2024 Octubre 141 67 208
2024 Septiembre 226 57 283
2024 Agosto 259 70 329
2024 Julio 202 41 243
2024 Junio 186 55 241
2024 Mayo 176 53 229
2024 Abril 235 46 281
2024 Marzo 252 56 308
2024 Febrero 324 68 392
2024 Enero 296 75 371
2023 Diciembre 264 52 316
2023 Noviembre 318 82 400
2023 Octubre 256 40 296
2023 Septiembre 237 45 282
2023 Agosto 192 28 220
2023 Julio 220 50 270
2023 Junio 189 37 226
2023 Mayo 290 53 343
2023 Abril 195 31 226
2023 Marzo 225 55 280
2023 Febrero 180 43 223
2023 Enero 190 48 238
2022 Diciembre 155 46 201
2022 Noviembre 116 58 174
2022 Octubre 106 27 133
2022 Septiembre 125 49 174
2022 Agosto 94 52 146
2022 Julio 104 39 143
2022 Junio 67 41 108
2022 Mayo 214 90 304
2022 Abril 306 60 366
2022 Marzo 336 94 430
2022 Febrero 313 66 379
2022 Enero 336 69 405
2021 Diciembre 246 74 320
2021 Noviembre 252 69 321
2021 Octubre 215 94 309
2021 Septiembre 199 63 262
2021 Agosto 205 53 258
2021 Julio 195 42 237
2021 Junio 153 42 195
2021 Mayo 138 49 187
2021 Abril 458 97 555
2021 Marzo 198 48 246
2021 Febrero 147 32 179
2021 Enero 138 35 173
2020 Diciembre 96 35 131
2020 Noviembre 89 41 130
2020 Octubre 56 18 74
2020 Septiembre 80 16 96
2020 Agosto 49 30 79
2020 Julio 39 17 56
2020 Junio 43 34 77
2020 Mayo 38 17 55
2020 Abril 18 12 30
2020 Marzo 15 9 24
2020 Febrero 1 2 3
2020 Enero 1 0 1
Mostrar todo

Siga este enlace para acceder al texto completo del artículo

Idiomas
Actas Dermo-Sifiliográficas
es en

¿Es usted profesional sanitario apto para prescribir o dispensar medicamentos?

Are you a health professional able to prescribe or dispense drugs?