Resident's Forum
FR- Risk of Nonmelanoma Skin Cancer in Patients on Hemodialysis
FR- Riesgo de cáncer cutáneo no melanoma en pacientes hemodializados
Leído
3477
Vecesse ha leído el artículo
1391
Total PDF
2086
Total HTML
Compartir estadísticas
array:24 [ "pii" => "S1578219019301076" "issn" => "15782190" "doi" => "10.1016/j.adengl.2017.12.026" "estado" => "S300" "fechaPublicacion" => "2019-05-01" "aid" => "1937" "copyright" => "Elsevier España, S.L.U. and AEDV" "copyrightAnyo" => "2018" "documento" => "article" "crossmark" => 1 "subdocumento" => "sco" "cita" => "Actas Dermosifiliogr. 2019;110:313-4" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 3 "HTML" => 3 ] "Traduccion" => array:1 [ "es" => array:18 [ "pii" => "S0001731018301261" "issn" => "00017310" "doi" => "10.1016/j.ad.2017.12.009" "estado" => "S300" "fechaPublicacion" => "2019-05-01" "aid" => "1937" "documento" => "article" "crossmark" => 1 "subdocumento" => "sco" "cita" => "Actas Dermosifiliogr. 2019;110:313-4" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 95 "formatos" => array:2 [ "HTML" => 66 "PDF" => 29 ] ] "es" => array:10 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Foro de Residentes</span>" "titulo" => "FR- Riesgo de cáncer cutáneo no melanoma en pacientes hemodializados" "tienePdf" => "es" "tieneTextoCompleto" => "es" "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "313" "paginaFinal" => "314" ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "FR- Risk of Nonmelanoma Skin Cancer in Patients on Hemodialysis" ] ] "contieneTextoCompleto" => array:1 [ "es" => true ] "contienePdf" => array:1 [ "es" => true ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "P. Aguayo Carreras, J. Tercedor Sánchez, R. Ruiz Villaverde" "autores" => array:3 [ 0 => array:2 [ "nombre" => "P." "apellidos" => "Aguayo Carreras" ] 1 => array:2 [ "nombre" => "J." "apellidos" => "Tercedor Sánchez" ] 2 => array:2 [ "nombre" => "R." "apellidos" => "Ruiz Villaverde" ] ] ] ] ] "idiomaDefecto" => "es" "Traduccion" => array:1 [ "en" => array:9 [ "pii" => "S1578219019301076" "doi" => "10.1016/j.adengl.2017.12.026" "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:1 [ "total" => 0 ] "idiomaDefecto" => "en" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219019301076?idApp=UINPBA000044" ] ] "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0001731018301261?idApp=UINPBA000044" "url" => "/00017310/0000011000000004/v2_201905040606/S0001731018301261/v2_201905040606/es/main.assets" ] ] "itemSiguiente" => array:19 [ "pii" => "S1578219019300952" "issn" => "15782190" "doi" => "10.1016/j.adengl.2019.03.003" "estado" => "S300" "fechaPublicacion" => "2019-05-01" "aid" => "2075" "copyright" => "Elsevier España, S.L.U. and AEDV" "documento" => "simple-article" "crossmark" => 1 "subdocumento" => "crp" "cita" => "Actas Dermosifiliogr. 2019;110:315-6" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 3 "HTML" => 3 ] "en" => array:11 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Practical Dermoscopy</span>" "titulo" => "Pohl-Pinkus Constrictions in Trichoscopy. What Do They Mean?" "tienePdf" => "en" "tieneTextoCompleto" => "en" "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "315" "paginaFinal" => "316" ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Constricciones de Pohl-Pinkus en tricoscopia. ¿Qué indican?" ] ] "contieneTextoCompleto" => array:1 [ "en" => true ] "contienePdf" => array:1 [ "en" => true ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:7 [ "identificador" => "fig0010" "etiqueta" => "Figure 2" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr2.jpeg" "Alto" => 563 "Ancho" => 750 "Tamanyo" => 68095 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Image of the border of the alopecic plaque acquired using a DermLite II Hybrid dermatoscope (3Gen Inc., CA, USA). Red arrows, hairs with Pohl-Pinkus or monilethrix-like constrictions; green arrows, exclamation-mark hairs with a thickened distal end; yellow arrows, yellow dots; orange arrows, short vellus hairs; blue arrow, angulated hair.</p>" ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "A. Lobato-Berezo, F. Olmos-Alpiste, R.M. Pujol, D. Saceda-Corralo" "autores" => array:4 [ 0 => array:2 [ "nombre" => "A." "apellidos" => "Lobato-Berezo" ] 1 => array:2 [ "nombre" => "F." "apellidos" => "Olmos-Alpiste" ] 2 => array:2 [ "nombre" => "R.M." "apellidos" => "Pujol" ] 3 => array:2 [ "nombre" => "D." "apellidos" => "Saceda-Corralo" ] ] ] ] ] "idiomaDefecto" => "en" "Traduccion" => array:1 [ "es" => array:9 [ "pii" => "S0001731018304411" "doi" => "10.1016/j.ad.2018.02.030" "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:1 [ "total" => 0 ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0001731018304411?idApp=UINPBA000044" ] ] "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219019300952?idApp=UINPBA000044" "url" => "/15782190/0000011000000004/v1_201905070820/S1578219019300952/v1_201905070820/en/main.assets" ] "itemAnterior" => array:19 [ "pii" => "S1578219019300940" "issn" => "15782190" "doi" => "10.1016/j.adengl.2019.03.002" "estado" => "S300" "fechaPublicacion" => "2019-05-01" "aid" => "2064" "copyright" => "Elsevier España, S.L.U. and AEDV" "documento" => "simple-article" "crossmark" => 1 "subdocumento" => "crp" "cita" => "Actas Dermosifiliogr. 2019;110:311-2" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 4 "HTML" => 4 ] "en" => array:11 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Case for Diagnosis</span>" "titulo" => "Ulceration on the Abdomen" "tienePdf" => "en" "tieneTextoCompleto" => "en" "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "311" "paginaFinal" => "312" ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Úlceras en abdomen" ] ] "contieneTextoCompleto" => array:1 [ "en" => true ] "contienePdf" => array:1 [ "en" => true ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:7 [ "identificador" => "fig0015" "etiqueta" => "Figure 3" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr3.jpeg" "Alto" => 745 "Ancho" => 1500 "Tamanyo" => 229738 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">A, Hematoxylin-eosin, original magnification<span class="elsevierStyleHsp" style=""></span>×<span class="elsevierStyleHsp" style=""></span>2.1. B, Hematoxylin-eosin, original magnification<span class="elsevierStyleHsp" style=""></span>×<span class="elsevierStyleHsp" style=""></span>65.</p>" ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "M.I. Martínez-González, S. Goula-Fernández, R. González-Pérez" "autores" => array:3 [ 0 => array:2 [ "nombre" => "M.I." "apellidos" => "Martínez-González" ] 1 => array:2 [ "nombre" => "S." "apellidos" => "Goula-Fernández" ] 2 => array:2 [ "nombre" => "R." "apellidos" => "González-Pérez" ] ] ] ] ] "idiomaDefecto" => "en" "Traduccion" => array:1 [ "es" => array:9 [ "pii" => "S0001731018304307" "doi" => "10.1016/j.ad.2017.11.023" "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:1 [ "total" => 0 ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0001731018304307?idApp=UINPBA000044" ] ] "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219019300940?idApp=UINPBA000044" "url" => "/15782190/0000011000000004/v1_201905070820/S1578219019300940/v1_201905070820/en/main.assets" ] "en" => array:13 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Resident's Forum</span>" "titulo" => "FR- Risk of Nonmelanoma Skin Cancer in Patients on Hemodialysis" "tieneTextoCompleto" => true "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "313" "paginaFinal" => "314" ] ] "autores" => array:1 [ 0 => array:4 [ "autoresLista" => "P. Aguayo Carreras, J. Tercedor Sánchez, R. Ruiz Villaverde" "autores" => array:3 [ 0 => array:4 [ "nombre" => "P. Aguayo" "apellidos" => "Carreras" "email" => array:1 [ 0 => "paula872190@gmail.com" ] "referencia" => array:2 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] 1 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">*</span>" "identificador" => "cor0005" ] ] ] 1 => array:3 [ "nombre" => "J. Tercedor" "apellidos" => "Sánchez" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff0010" ] ] ] 2 => array:3 [ "nombre" => "R. Ruiz" "apellidos" => "Villaverde" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] ] ] ] "afiliaciones" => array:2 [ 0 => array:3 [ "entidad" => "Servicio de Dermatología, Hospital Universitario Campus de la Salud, Granada, Spain" "etiqueta" => "a" "identificador" => "aff0005" ] 1 => array:3 [ "entidad" => "Servicio de Dermatología, Hospital Universitario Virgen de las Nieves, Granada, Spain" "etiqueta" => "b" "identificador" => "aff0010" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "⁎" "correspondencia" => "Corresponding author." ] ] ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "FR- Riesgo de cáncer cutáneo no melanoma en pacientes hemodializados" ] ] "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">Wang et al.<a class="elsevierStyleCrossRef" href="#bib0030"><span class="elsevierStyleSup">1</span></a> recently published an interesting article in the <span class="elsevierStyleItalic">British Journal of Dermatology</span> on the risk of skin cancer in patients on chronic hemodialysis. That study found an increased risk of skin cancer in patients undergoing chronic hemodialysis of 1.58 compared to that of the general population. The authors mainly attribute this increased risk to the increase in inflammatory biomarkers caused by the uremic pruritis suffered by these patients. This situation is analogous to the association between inflammatory bowel disease and colorectal cancer. It was also found that uremia can lead to the impairment of DNA repair,<a class="elsevierStyleCrossRef" href="#bib0035"><span class="elsevierStyleSup">2</span></a> a finding that had been published 4 years earlier on an initial review of their database. In their database, this risk is higher in patients aged between 20 and 39 years and falls gradually with age.</p><p id="par0010" class="elsevierStylePara elsevierViewall">We would like to report the experience of our research group, which, in 1995, published a multivariate analysis of aging markers in patients on hemodialysis.<a class="elsevierStyleCrossRef" href="#bib0040"><span class="elsevierStyleSup">3</span></a> In this study, we were able to show that hemodialysis is a technique that accelerated skin aging in our patients with chronic kidney disease. In our patients, we found reduced hydration of the stratum corneum, increased Favré-Racouchot senile elastosis with cysts and comedones, and increased actinic keratosis independent of age. The sample size did not allow us to establish a statistically significant link with basal cell carcinoma. Nevertheless, all signs of photoaging found in our patients presented a link with the duration of hemodialysis. Renal failure thus produces accelerated pathologic aging. The prognosis for patients with chronic kidney disease continues to be extremely poor and remains so despite improvements in treatment options. We therefore hypothesize that immunosuppression is age-related and therefore affected by hemodialysis.<a class="elsevierStyleCrossRef" href="#bib0045"><span class="elsevierStyleSup">4</span></a></p><p id="par0015" class="elsevierStylePara elsevierViewall">White et al.<a class="elsevierStyleCrossRef" href="#bib0050"><span class="elsevierStyleSup">5</span></a> recently corroborated the similarity between the physiological aging process and hemodialysis in patients with chronic kidney disease. The principal molecular mechanisms affected in both processes and which lead us to believe that there is a crossover between them include impaired proteostasis, mitochondrial dysfunction, post-translational protein modification, and senescence and telomere shortening. We agree that uremia is the key process in the pathophysiology of this accelerated aging process and induces increased apoptosis, necroptosis, and autophagy, and that dialysis may even accelerate the processes of apoptosis per se.</p><p id="par0020" class="elsevierStylePara elsevierViewall">In light of these arguments, we believe that skin cancer in patients on hemodialysis must also be considered as an aging marker and the increased incidence due to the inflammatory cascade caused by the uremia should not be considered as the sole causal factor. It is part of a multifactor process that is more complex and similar to the physiological aging process, where oxidative stress is one more factor to take into account.</p></span>" "pdfFichero" => "main.pdf" "tienePdf" => true "PalabrasClave" => array:1 [ "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Keywords" "identificador" => "xpalclavsec1107578" "palabras" => array:4 [ 0 => "Skin cancer" 1 => "Hemodialysis" 2 => "Skin aging" 3 => "Chronic kidney disease" ] ] ] ] "NotaPie" => array:1 [ 0 => array:2 [ "etiqueta" => "☆" "nota" => "<p class="elsevierStyleNotepara" id="npar0005">Please cite this article as: Carreras PA, Sánchez JT, Villaverde RR. FR- Riesgo de cáncer cutáneo no melanoma en pacientes hemodializados. Actas Dermosifiliogr. 2019;110:313–314.</p>" ] ] "bibliografia" => array:2 [ "titulo" => "References" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0015" "bibliografiaReferencia" => array:5 [ 0 => array:3 [ "identificador" => "bib0030" "etiqueta" => "1" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Risk of skin cancer in patients on chronic haemodialysis: A nationwide, population-based study in Taiwan" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "C.C. Wang" 1 => "C.H. Tang" 2 => "C.Y. Wang" 3 => "S.Y. Huang" 4 => "Y.M. Sue" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1111/bjd.14789" "Revista" => array:6 [ "tituloSerie" => "Br J Dermatol" "fecha" => "2016" "volumen" => "175" "paginaInicial" => "1175" "paginaFinal" => "1182" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/27273242" "web" => "Medline" ] ] ] ] ] ] ] ] 1 => array:3 [ "identificador" => "bib0035" "etiqueta" => "2" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Increased risk of cancer in chronic dialysis patients: A population-based cohort study in Taiwan" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "H.F. Lin" 1 => "Y.H. Li" 2 => "C.H. Wang" 3 => "C.L. Chou" 4 => "D.J. Kuo" 5 => "T.C. Fang" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1093/ndt/gfr464" "Revista" => array:6 [ "tituloSerie" => "Nephrol Dial Transplant" "fecha" => "2012" "volumen" => "27" "paginaInicial" => "1585" "paginaFinal" => "1590" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/21862456" "web" => "Medline" ] ] ] ] ] ] ] ] 2 => array:3 [ "identificador" => "bib0040" "etiqueta" => "3" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Multivariate analysis of cutaneous markers of aging in chronic hemodialyzed patients" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "J. Tercedor" 1 => "B. López-Hernández" 2 => "J.M. Ródenas" 3 => "M. Delgado-Rodríguez" 4 => "S. Cerezo" 5 => "S. Serrano-Ortega" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Int J Dermatol" "fecha" => "1995" "volumen" => "34" "paginaInicial" => "546" "paginaFinal" => "550" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/7591434" "web" => "Medline" ] ] ] ] ] ] ] ] 3 => array:3 [ "identificador" => "bib0045" "etiqueta" => "4" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Sking aging and photoaging: An overview" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "B.A. Gilrescht" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "J Am Acad Dermatol" "fecha" => "1989" "volumen" => "21" "paginaInicial" => "610" "paginaFinal" => "613" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/2476468" "web" => "Medline" ] ] ] ] ] ] ] ] 4 => array:3 [ "identificador" => "bib0050" "etiqueta" => "5" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Aging and uremia: Is there cellular and molecular crossover?" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "W.E. White" 1 => "M.M. Yaqoob" 2 => "S.M. Harwood" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.5527/wjn.v4.i1.19" "Revista" => array:6 [ "tituloSerie" => "World J Nephrol" "fecha" => "2015" "volumen" => "4" "paginaInicial" => "19" "paginaFinal" => "30" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/25664244" "web" => "Medline" ] ] ] ] ] ] ] ] ] ] ] ] ] "idiomaDefecto" => "en" "url" => "/15782190/0000011000000004/v1_201905070820/S1578219019301076/v1_201905070820/en/main.assets" "Apartado" => array:4 [ "identificador" => "34945" "tipo" => "SECCION" "en" => array:2 [ "titulo" => "Resident's Forum" "idiomaDefecto" => true ] "idiomaDefecto" => "en" ] "PDF" => "https://static.elsevier.es/multimedia/15782190/0000011000000004/v1_201905070820/S1578219019301076/v1_201905070820/en/main.pdf?idApp=UINPBA000044&text.app=https://actasdermo.org/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219019301076?idApp=UINPBA000044" ]
| año/Mes | Html | Total | |
|---|---|---|---|
| 2024 Noviembre | 8 | 6 | 14 |
| 2024 Octubre | 62 | 38 | 100 |
| 2024 Septiembre | 58 | 26 | 84 |
| 2024 Agosto | 93 | 60 | 153 |
| 2024 Julio | 58 | 24 | 82 |
| 2024 Junio | 55 | 32 | 87 |
| 2024 Mayo | 67 | 28 | 95 |
| 2024 Abril | 89 | 22 | 111 |
| 2024 Marzo | 73 | 29 | 102 |
| 2024 Febrero | 63 | 36 | 99 |
| 2024 Enero | 59 | 32 | 91 |
| 2023 Diciembre | 43 | 20 | 63 |
| 2023 Noviembre | 91 | 26 | 117 |
| 2023 Octubre | 51 | 20 | 71 |
| 2023 Septiembre | 43 | 31 | 74 |
| 2023 Agosto | 40 | 12 | 52 |
| 2023 Julio | 33 | 30 | 63 |
| 2023 Junio | 36 | 23 | 59 |
| 2023 Mayo | 31 | 17 | 48 |
| 2023 Abril | 24 | 18 | 42 |
| 2023 Marzo | 23 | 22 | 45 |
| 2023 Febrero | 25 | 20 | 45 |
| 2023 Enero | 19 | 29 | 48 |
| 2022 Diciembre | 32 | 34 | 66 |
| 2022 Noviembre | 27 | 28 | 55 |
| 2022 Octubre | 19 | 24 | 43 |
| 2022 Septiembre | 18 | 30 | 48 |
| 2022 Agosto | 18 | 37 | 55 |
| 2022 Julio | 19 | 30 | 49 |
| 2022 Junio | 30 | 36 | 66 |
| 2022 Mayo | 27 | 33 | 60 |
| 2022 Abril | 29 | 20 | 49 |
| 2022 Marzo | 34 | 39 | 73 |
| 2022 Febrero | 24 | 17 | 41 |
| 2022 Enero | 31 | 30 | 61 |
| 2021 Diciembre | 28 | 34 | 62 |
| 2021 Noviembre | 29 | 34 | 63 |
| 2021 Octubre | 30 | 54 | 84 |
| 2021 Septiembre | 18 | 25 | 43 |
| 2021 Agosto | 20 | 22 | 42 |
| 2021 Julio | 14 | 15 | 29 |
| 2021 Junio | 18 | 16 | 34 |
| 2021 Mayo | 35 | 35 | 70 |
| 2021 Abril | 90 | 37 | 127 |
| 2021 Marzo | 55 | 19 | 74 |
| 2021 Febrero | 71 | 15 | 86 |
| 2021 Enero | 37 | 12 | 49 |
| 2020 Diciembre | 28 | 12 | 40 |
| 2020 Noviembre | 12 | 13 | 25 |
| 2020 Octubre | 11 | 18 | 29 |
| 2020 Septiembre | 29 | 8 | 37 |
| 2020 Agosto | 23 | 11 | 34 |
| 2020 Julio | 16 | 10 | 26 |
| 2020 Junio | 25 | 21 | 46 |
| 2020 Mayo | 14 | 8 | 22 |
| 2020 Abril | 14 | 8 | 22 |
| 2020 Marzo | 12 | 5 | 17 |
| 2020 Febrero | 2 | 0 | 2 |
| 2019 Mayo | 3 | 0 | 3 |
Mostrar todo
