array:24 [
  "pii" => "S1578219019300356"
  "issn" => "15782190"
  "doi" => "10.1016/j.adengl.2019.02.003"
  "estado" => "S300"
  "fechaPublicacion" => "2019-07-01"
  "aid" => "2069"
  "copyright" => "Elsevier España, S.L.U. and AEDV"
  "copyrightAnyo" => "2018"
  "documento" => "simple-article"
  "crossmark" => 1
  "subdocumento" => "crp"
  "cita" => "Actas Dermosifiliogr. 2019;110:497-8"
  "abierto" => array:3 [
    "ES" => true
    "ES2" => true
    "LATM" => true
  ]
  "gratuito" => true
  "lecturas" => array:2 [
    "total" => 2
    "formatos" => array:2 [
      "HTML" => 1
      "PDF" => 1
    ]
  ]
  "Traduccion" => array:1 [
    "es" => array:19 [
      "pii" => "S0001731018304356"
      "issn" => "00017310"
      "doi" => "10.1016/j.ad.2017.11.025"
      "estado" => "S300"
      "fechaPublicacion" => "2019-07-01"
      "aid" => "2069"
      "copyright" => "AEDV"
      "documento" => "simple-article"
      "crossmark" => 1
      "subdocumento" => "crp"
      "cita" => "Actas Dermosifiliogr. 2019;110:497-8"
      "abierto" => array:3 [
        "ES" => true
        "ES2" => true
        "LATM" => true
      ]
      "gratuito" => true
      "lecturas" => array:2 [
        "total" => 318
        "formatos" => array:2 [
          "HTML" => 242
          "PDF" => 76
        ]
      ]
      "es" => array:11 [
        "idiomaDefecto" => true
        "cabecera" => "<span class="elsevierStyleTextfn">Casos para el diagn&#243;stico</span>"
        "titulo" => "Tumoraci&#243;n occipital de r&#225;pido crecimiento"
        "tienePdf" => "es"
        "tieneTextoCompleto" => "es"
        "paginas" => array:1 [
          0 => array:2 [
            "paginaInicial" => "497"
            "paginaFinal" => "498"
          ]
        ]
        "titulosAlternativos" => array:1 [
          "en" => array:1 [
            "titulo" => "Fast-Growing Occipital Tumor"
          ]
        ]
        "contieneTextoCompleto" => array:1 [
          "es" => true
        ]
        "contienePdf" => array:1 [
          "es" => true
        ]
        "resumenGrafico" => array:2 [
          "original" => 0
          "multimedia" => array:7 [
            "identificador" => "fig0015"
            "etiqueta" => "Figura 3"
            "tipo" => "MULTIMEDIAFIGURA"
            "mostrarFloat" => true
            "mostrarDisplay" => false
            "figura" => array:1 [
              0 => array:4 [
                "imagen" => "gr3.jpeg"
                "Alto" => 498
                "Ancho" => 900
                "Tamanyo" => 226829
              ]
            ]
            "descripcion" => array:1 [
              "es" => "<p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Hematoxilina-eosina &#215;4&#46;</p>"
            ]
          ]
        ]
        "autores" => array:1 [
          0 => array:2 [
            "autoresLista" => "E&#46; Varas-Meis, C&#46; Prada-Garc&#237;a, P&#46; Fern&#225;ndez-Canga, M&#46;&#193;&#46; Rodriguez-Prieto"
            "autores" => array:4 [
              0 => array:2 [
                "nombre" => "E&#46;"
                "apellidos" => "Varas-Meis"
              ]
              1 => array:2 [
                "nombre" => "C&#46;"
                "apellidos" => "Prada-Garc&#237;a"
              ]
              2 => array:2 [
                "nombre" => "P&#46;"
                "apellidos" => "Fern&#225;ndez-Canga"
              ]
              3 => array:2 [
                "nombre" => "M&#46;&#193;&#46;"
                "apellidos" => "Rodriguez-Prieto"
              ]
            ]
          ]
        ]
      ]
      "idiomaDefecto" => "es"
      "Traduccion" => array:1 [
        "en" => array:9 [
          "pii" => "S1578219019300356"
          "doi" => "10.1016/j.adengl.2019.02.003"
          "estado" => "S300"
          "subdocumento" => ""
          "abierto" => array:3 [
            "ES" => true
            "ES2" => true
            "LATM" => true
          ]
          "gratuito" => true
          "lecturas" => array:1 [
            "total" => 0
          ]
          "idiomaDefecto" => "en"
          "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219019300356?idApp=UINPBA000044"
        ]
      ]
      "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0001731018304356?idApp=UINPBA000044"
      "url" => "/00017310/0000011000000006/v1_201907020633/S0001731018304356/v1_201907020633/es/main.assets"
    ]
  ]
  "itemSiguiente" => array:19 [
    "pii" => "S1578219019301660"
    "issn" => "15782190"
    "doi" => "10.1016/j.adengl.2017.12.027"
    "estado" => "S300"
    "fechaPublicacion" => "2019-07-01"
    "aid" => "2007"
    "copyright" => "Elsevier Espa&#241;a&#44; S&#46;L&#46;U&#46; and AEDV"
    "documento" => "article"
    "crossmark" => 1
    "subdocumento" => "sco"
    "cita" => "Actas Dermosifiliogr. 2019;110:499-500"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:1 [
      "total" => 0
    ]
    "en" => array:10 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">Resident&#39;s Forum</span>"
      "titulo" => "RF - Epidermal Growth Factor Receptor Inhibitors and Skin Toxicity&#58; The Search for a Management Protocol"
      "tienePdf" => "en"
      "tieneTextoCompleto" => "en"
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "499"
          "paginaFinal" => "500"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "es" => array:1 [
          "titulo" => "FR - Inhibidores del factor de crecimiento epid&#233;rmico y toxicidad cut&#225;nea&#58; en busca de un protocolo de manejo"
        ]
      ]
      "contieneTextoCompleto" => array:1 [
        "en" => true
      ]
      "contienePdf" => array:1 [
        "en" => true
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "J&#46;J&#46; Andr&#233;s-Lencina, R&#46; Arag&#243;n-Miguel, A&#46; Calleja-Algarra"
          "autores" => array:3 [
            0 => array:2 [
              "nombre" => "J&#46;J&#46;"
              "apellidos" => "Andr&#233;s-Lencina"
            ]
            1 => array:2 [
              "nombre" => "R&#46;"
              "apellidos" => "Arag&#243;n-Miguel"
            ]
            2 => array:2 [
              "nombre" => "A&#46;"
              "apellidos" => "Calleja-Algarra"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "en"
    "Traduccion" => array:1 [
      "es" => array:9 [
        "pii" => "S0001731018302928"
        "doi" => "10.1016/j.ad.2017.12.019"
        "estado" => "S300"
        "subdocumento" => ""
        "abierto" => array:3 [
          "ES" => true
          "ES2" => true
          "LATM" => true
        ]
        "gratuito" => true
        "lecturas" => array:1 [
          "total" => 0
        ]
        "idiomaDefecto" => "es"
        "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0001731018302928?idApp=UINPBA000044"
      ]
    ]
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219019301660?idApp=UINPBA000044"
    "url" => "/15782190/0000011000000006/v1_201907040838/S1578219019301660/v1_201907040838/en/main.assets"
  ]
  "itemAnterior" => array:18 [
    "pii" => "S1578219019300381"
    "issn" => "15782190"
    "doi" => "10.1016/j.adengl.2019.02.006"
    "estado" => "S300"
    "fechaPublicacion" => "2019-07-01"
    "aid" => "2118"
    "documento" => "simple-article"
    "crossmark" => 1
    "subdocumento" => "crp"
    "cita" => "Actas Dermosifiliogr. 2019;110:495-6"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:1 [
      "total" => 0
    ]
    "en" => array:11 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">Case for Diagnosis</span>"
      "titulo" => "Progressive skin ulcers in extremities"
      "tienePdf" => "en"
      "tieneTextoCompleto" => "en"
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "495"
          "paginaFinal" => "496"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "es" => array:1 [
          "titulo" => "&#218;lceras progresivas localizadas en las extremidades"
        ]
      ]
      "contieneTextoCompleto" => array:1 [
        "en" => true
      ]
      "contienePdf" => array:1 [
        "en" => true
      ]
      "resumenGrafico" => array:2 [
        "original" => 0
        "multimedia" => array:6 [
          "identificador" => "fig0005"
          "etiqueta" => "Figure 1"
          "tipo" => "MULTIMEDIAFIGURA"
          "mostrarFloat" => true
          "mostrarDisplay" => false
          "figura" => array:1 [
            0 => array:4 [
              "imagen" => "gr1.jpeg"
              "Alto" => 520
              "Ancho" => 500
              "Tamanyo" => 41737
            ]
          ]
        ]
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "S&#46; Castillo-Loaiza, C&#46;J&#46; D&#237;az, L&#46;F&#46; Cardenas"
          "autores" => array:3 [
            0 => array:2 [
              "nombre" => "S&#46;"
              "apellidos" => "Castillo-Loaiza"
            ]
            1 => array:2 [
              "nombre" => "C&#46;J&#46;"
              "apellidos" => "D&#237;az"
            ]
            2 => array:2 [
              "nombre" => "L&#46;F&#46;"
              "apellidos" => "Cardenas"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "en"
    "Traduccion" => array:1 [
      "es" => array:9 [
        "pii" => "S0001731018305428"
        "doi" => "10.1016/j.ad.2018.01.017"
        "estado" => "S300"
        "subdocumento" => ""
        "abierto" => array:3 [
          "ES" => true
          "ES2" => true
          "LATM" => true
        ]
        "gratuito" => true
        "lecturas" => array:1 [
          "total" => 0
        ]
        "idiomaDefecto" => "es"
        "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0001731018305428?idApp=UINPBA000044"
      ]
    ]
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219019300381?idApp=UINPBA000044"
    "url" => "/15782190/0000011000000006/v1_201907040838/S1578219019300381/v1_201907040838/en/main.assets"
  ]
  "en" => array:17 [
    "idiomaDefecto" => true
    "cabecera" => "<span class="elsevierStyleTextfn">Case for Diagnosis</span>"
    "titulo" => "Fast-Growing Occipital Tumor"
    "tieneTextoCompleto" => true
    "paginas" => array:1 [
      0 => array:2 [
        "paginaInicial" => "497"
        "paginaFinal" => "498"
      ]
    ]
    "autores" => array:1 [
      0 => array:4 [
        "autoresLista" => "E&#46; Varas-Meis, C&#46; Prada-Garc&#237;a, P&#46; Fern&#225;ndez-Canga, M&#46;&#193;&#46; Rodriguez-Prieto"
        "autores" => array:4 [
          0 => array:4 [
            "nombre" => "E&#46;"
            "apellidos" => "Varas-Meis"
            "email" => array:1 [
              0 => "edu.varas.meis@gmail.com"
            ]
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">&#42;</span>"
                "identificador" => "cor0005"
              ]
            ]
          ]
          1 => array:2 [
            "nombre" => "C&#46;"
            "apellidos" => "Prada-Garc&#237;a"
          ]
          2 => array:2 [
            "nombre" => "P&#46;"
            "apellidos" => "Fern&#225;ndez-Canga"
          ]
          3 => array:2 [
            "nombre" => "M&#46;&#193;&#46;"
            "apellidos" => "Rodriguez-Prieto"
          ]
        ]
        "afiliaciones" => array:1 [
          0 => array:2 [
            "entidad" => "Servicio de Dermatolog&#237;a&#44; Complejo Asistencial Universitario de Le&#243;n&#44; Le&#243;n&#44; Espa&#241;a"
            "identificador" => "aff0005"
          ]
        ]
        "correspondencia" => array:1 [
          0 => array:3 [
            "identificador" => "cor0005"
            "etiqueta" => "&#8270;"
            "correspondencia" => "Corresponding author&#46;"
          ]
        ]
      ]
    ]
    "titulosAlternativos" => array:1 [
      "es" => array:1 [
        "titulo" => "Tumoraci&#243;n occipital de r&#225;pido crecimiento"
      ]
    ]
    "resumenGrafico" => array:2 [
      "original" => 0
      "multimedia" => array:7 [
        "identificador" => "fig0010"
        "etiqueta" => "Figure 2"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr2.jpeg"
            "Alto" => 459
            "Ancho" => 900
            "Tamanyo" => 202518
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Hematoxylin-eosin&#44; original magnification &#215;2&#46;</p>"
        ]
      ]
    ]
    "textoCompleto" => "<span class="elsevierStyleSections"><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0005">Medical History</span><p id="par0005" class="elsevierStylePara elsevierViewall">The patient was an 89-year-old woman who had been diagnosed 40 years earlier with multiple trichilemmal cysts&#44; and had no other medical history of interest&#46; She was referred to our clinic for an asymptomatic ulcerated lesion on the scalp that had appeared 2 months earlier&#46;</p></span><span id="sec0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0010">Physical Examination</span><p id="par0010" class="elsevierStylePara elsevierViewall">Physical examination revealed a solid-to-keratotic&#44; exophytic&#44; crateriform tumor of 4&#160;cm in diameter located in the occipital region and adhered to deep planes &#40;<a class="elsevierStyleCrossRef" href="#fig0005">Fig&#46; 1</a>&#41;&#46; The lesion was surrounded by multiple previously diagnosed trichilemmal cysts&#46; No other lesions were detected&#44; and lymph node enlargement was absent&#46;</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia></span><span id="sec0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0015">Histopathology</span><p id="par0015" class="elsevierStylePara elsevierViewall">The lesion was excised for pathological examination&#44; which revealed a well-delimited and unencapsulated epithelial proliferation located in the superficial reticular dermis with an endophytic and exophytic growth pattern&#46; This hyperplasia consisted of multiple partially cystic epithelial cords and lobules&#44; with peripheral palisading and central trichilemmal keratinization&#46; More detailed analysis revealed mild-to-moderate cellular atypia&#44; with no aberrant mitoses or areas of necrosis &#40;<a class="elsevierStyleCrossRefs" href="#fig0010">Figs&#46; 2 and 3</a>&#41;&#46;</p><elsevierMultimedia ident="fig0010"></elsevierMultimedia><elsevierMultimedia ident="fig0015"></elsevierMultimedia><p id="par0020" class="elsevierStylePara elsevierViewall">What Is Your Diagnosis&#63;</p></span><span id="sec0020" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0020">Diagnosis</span><p id="par0025" class="elsevierStylePara elsevierViewall">Proliferating pilar tumor &#40;PPT&#41;&#46;</p></span><span id="sec0025" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0025">Course</span><p id="par0030" class="elsevierStylePara elsevierViewall">The patient showed no recurrence after 6 months of follow-up&#46;</p></span><span id="sec0030" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0030">Comment</span><p id="par0035" class="elsevierStylePara elsevierViewall">PPT is an adnexal tumor derived from the external radicular membrane of the hair follicle&#46;<a class="elsevierStyleCrossRef" href="#bib0050"><span class="elsevierStyleSup">1</span></a> It usually presents as an exophytic scalp tumor&#44; in many cases with ulceration&#44; bleeding&#44; and&#47;or superinfection&#44; and typically affects women aged 40 years and older&#46; However&#44; cases involving tumors in atypical locations&#44; including the thorax&#44; back&#44; buttock&#44; nose&#44; and vulva&#44; have also been described&#46;<a class="elsevierStyleCrossRef" href="#bib0055"><span class="elsevierStyleSup">2</span></a> In most cases PPT arises from a pre-existing trichilemmal cyst&#44; although de novo forms&#44; which develop in the absence of pre-existing lesions&#44; are also described&#46;<a class="elsevierStyleCrossRef" href="#bib0060"><span class="elsevierStyleSup">3</span></a></p><p id="par0040" class="elsevierStylePara elsevierViewall">Histologically&#44; PPT is characterized by hyperplasia consisting of solid or partially cystic epithelial cords or lobules&#44; with peripheral palisading and trichilemmal keratinization&#46;<a class="elsevierStyleCrossRefs" href="#bib0050"><span class="elsevierStyleSup">1&#8211;3</span></a> Areas of necrosis&#44; anaplastic cells&#44; and aberrant mitoses are common&#46;<a class="elsevierStyleCrossRefs" href="#bib0060"><span class="elsevierStyleSup">3&#44;4</span></a> PPT can be associated with foreign body reaction&#44; dystrophic calcification&#44; squamous eddies&#44; and areas of vacuolization or dyskeratosis&#46;<a class="elsevierStyleCrossRefs" href="#bib0055"><span class="elsevierStyleSup">2&#44;4</span></a></p><p id="par0045" class="elsevierStylePara elsevierViewall">When differentiating PPT from squamous cell carcinoma&#44; foci of trichilemmal keratinization&#44; sharp delimitation&#44; areas of calcification&#44; and the absence of premalignant epidermal lesions help orient the diagnosis towards PPT&#46;<a class="elsevierStyleCrossRef" href="#bib0070"><span class="elsevierStyleSup">5</span></a> The differential diagnosis should also include sebaceous carcinoma&#44; clear cell hidradenocarcinoma&#44; pilomatrixoma&#44; and trichoblastoma&#46;<a class="elsevierStyleCrossRefs" href="#bib0075"><span class="elsevierStyleSup">6&#44;7</span></a></p><p id="par0050" class="elsevierStylePara elsevierViewall">PPT follows an unpredictable course and lies on a spectrum ranging from benign trichilemmal cysts with minimal epithelial proliferation to malignant PPT with local invasion&#44; a tendency to recur&#44; and occasional distant metastases&#46;<a class="elsevierStyleCrossRefs" href="#bib0060"><span class="elsevierStyleSup">3&#44;5&#44;8</span></a> An infiltrative pattern with cellular anaplasia&#44; atypical mitoses&#44; and&#47;or areas of necrosis are considered histological markers of poor prognosis&#46;<a class="elsevierStyleCrossRef" href="#bib0055"><span class="elsevierStyleSup">2</span></a> The treatment of choice is exeresis with wide margins &#40;1&#8211;2&#160;cm&#41; or Mohs micrographic surgery&#44; although a good therapeutic response has also been reported in patients treated with radiotherapy&#46;<a class="elsevierStyleCrossRefs" href="#bib0085"><span class="elsevierStyleSup">8&#44;9</span></a></p><p id="par0055" class="elsevierStylePara elsevierViewall">In conclusion&#44; we describe a representative case of a little-known adnexal lesion&#44; knowledge of which is necessary in order to select the appropriate therapeutic measures&#46;</p></span><span id="sec0035" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0035">Conflicts of Interest</span><p id="par0060" class="elsevierStylePara elsevierViewall">The authors declare that they have no conflicts of interest&#46;</p></span></span>"
    "textoCompletoSecciones" => array:1 [
      "secciones" => array:8 [
        0 => array:2 [
          "identificador" => "sec0005"
          "titulo" => "Medical History"
        ]
        1 => array:2 [
          "identificador" => "sec0010"
          "titulo" => "Physical Examination"
        ]
        2 => array:2 [
          "identificador" => "sec0015"
          "titulo" => "Histopathology"
        ]
        3 => array:2 [
          "identificador" => "sec0020"
          "titulo" => "Diagnosis"
        ]
        4 => array:2 [
          "identificador" => "sec0025"
          "titulo" => "Course"
        ]
        5 => array:2 [
          "identificador" => "sec0030"
          "titulo" => "Comment"
        ]
        6 => array:2 [
          "identificador" => "sec0035"
          "titulo" => "Conflicts of Interest"
        ]
        7 => array:1 [
          "titulo" => "References"
        ]
      ]
    ]
    "pdfFichero" => "main.pdf"
    "tienePdf" => true
    "fechaRecibido" => "2017-07-11"
    "fechaAceptado" => "2017-11-23"
    "NotaPie" => array:1 [
      0 => array:2 [
        "etiqueta" => "&#9734;"
        "nota" => "<p class="elsevierStyleNotepara" id="npar0005">Please cite this article as&#58; Varas-Meis E&#44; Prada-Garc&#237;a C&#44; Fern&#225;ndez-Canga P&#44; Rodriguez-Prieto M&#193;&#46; Tumoraci&#243;n occipital de r&#225;pido crecimiento&#46; Actas Dermosifiliogr&#46; 2019&#59;110&#58;497&#8211;498&#46;</p>"
      ]
    ]
    "multimedia" => array:3 [
      0 => array:6 [
        "identificador" => "fig0005"
        "etiqueta" => "Figure 1"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr1.jpeg"
            "Alto" => 647
            "Ancho" => 750
            "Tamanyo" => 63727
          ]
        ]
      ]
      1 => array:7 [
        "identificador" => "fig0010"
        "etiqueta" => "Figure 2"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr2.jpeg"
            "Alto" => 459
            "Ancho" => 900
            "Tamanyo" => 202518
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Hematoxylin-eosin&#44; original magnification &#215;2&#46;</p>"
        ]
      ]
      2 => array:7 [
        "identificador" => "fig0015"
        "etiqueta" => "Figure 3"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr3.jpeg"
            "Alto" => 498
            "Ancho" => 900
            "Tamanyo" => 226829
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Hematoxylin-eosin&#44; original magnification &#215;4&#46;</p>"
        ]
      ]
    ]
    "bibliografia" => array:2 [
      "titulo" => "References"
      "seccion" => array:1 [
        0 => array:2 [
          "identificador" => "bibs0015"
          "bibliografiaReferencia" => array:9 [
            0 => array:3 [
              "identificador" => "bib0050"
              "etiqueta" => "1"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Proliferating trichilemmal tumors&#58; Clinicopathologic evaluation is a guide to biologic behavior"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "A&#46;L&#46; Folpe"
                            1 => "A&#46;K&#46; Reisenauer"
                            2 => "T&#46; Mentzel"
                            3 => "A&#46; R&#252;tten"
                            4 => "A&#46;R&#46; Solomon"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "J Cutan Pathol"
                        "fecha" => "2003"
                        "volumen" => "30"
                        "paginaInicial" => "492"
                        "paginaFinal" => "498"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            1 => array:3 [
              "identificador" => "bib0055"
              "etiqueta" => "2"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Proliferating pilar tumors&#58; A clinicopathologic study of 76 cases with a proposal for definition of benign and malignant variants"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "J&#46; Ye"
                            1 => "O&#46; Nappi"
                            2 => "P&#46;E&#46; Swanson"
                            3 => "J&#46;W&#46; Patterson"
                            4 => "M&#46;R&#46; Wick"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Am J Clin Pathol"
                        "fecha" => "2004"
                        "volumen" => "122"
                        "paginaInicial" => "566"
                        "paginaFinal" => "574"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            2 => array:3 [
              "identificador" => "bib0060"
              "etiqueta" => "3"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Proliferating trichilemmal tumors&#58; A review of the literature"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "A&#46;K&#46; Satyaprakash"
                            1 => "D&#46;J&#46; Sheehan"
                            2 => "O&#46;P&#46; Sang&#252;eza"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Dermatol Surg"
                        "fecha" => "2007"
                        "volumen" => "33"
                        "paginaInicial" => "1102"
                        "paginaFinal" => "1108"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            3 => array:3 [
              "identificador" => "bib0065"
              "etiqueta" => "4"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Proliferating epithelial cysts&#46; Clinicopathological analysis of 96 cases"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "P&#46; Sau"
                            1 => "J&#46;H&#46; Graham"
                            2 => "E&#46;B&#46; Helwig"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "J Cutan Pathol"
                        "fecha" => "1995"
                        "volumen" => "22"
                        "paginaInicial" => "394"
                        "paginaFinal" => "406"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8594071"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            4 => array:3 [
              "identificador" => "bib0070"
              "etiqueta" => "5"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Proliferating trichilemmal cyst&#58; A simulant of squamous cell carcinoma"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "M&#46;H&#46; Brownstein"
                            1 => "D&#46;J&#46; Arluk"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Cancer"
                        "fecha" => "1981"
                        "volumen" => "48"
                        "paginaInicial" => "1207"
                        "paginaFinal" => "1214"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            5 => array:3 [
              "identificador" => "bib0075"
              "etiqueta" => "6"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Malignant pilar tumor of the scalp&#58; A case report and review of literature"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:7 [
                            0 => "M&#46; Siddha"
                            1 => "A&#46; Budrukkar"
                            2 => "T&#46; Shet"
                            3 => "M&#46; Deshpande"
                            4 => "A&#46; Basu"
                            5 => "N&#46; Patil"
                            6 => "R&#46; Bhalavat"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "J Cancer Res Ther"
                        "fecha" => "2007"
                        "volumen" => "3"
                        "paginaInicial" => "240"
                        "paginaFinal" => "243"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            6 => array:3 [
              "identificador" => "bib0080"
              "etiqueta" => "7"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Malignant Proliferating Trichilemmal cyst&#58; A case report with review of literature"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "P&#46;K&#46; Garg"
                            1 => "A&#46; Dangi"
                            2 => "N&#46; Khurana"
                            3 => "N&#46;S&#46; Hadke"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Malays J Pathol"
                        "fecha" => "2009"
                        "volumen" => "31"
                        "paginaInicial" => "71"
                        "paginaFinal" => "76"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            7 => array:3 [
              "identificador" => "bib0085"
              "etiqueta" => "8"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Malignant proliferating trichilemmal tumor treated with Mohs surgery&#58; Proposed protocol for diagnostic work-up and treatment"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "D&#46;R&#46; Fieleke"
                            1 => "G&#46;D&#46; Goldstein"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Dermatol Surg"
                        "fecha" => "2015"
                        "volumen" => "41"
                        "paginaInicial" => "292"
                        "paginaFinal" => "294"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            8 => array:3 [
              "identificador" => "bib0090"
              "etiqueta" => "9"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Malignant proliferating trichilemmal tumor treated with radical radiotherapy&#58; A case report and literature review"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "D&#46; Sutherland"
                            1 => "K&#46; Roth"
                            2 => "E&#46; Yu"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:4 [
                        "tituloSerie" => "Cureus"
                        "fecha" => "2017"
                        "volumen" => "9"
                        "paginaInicial" => "e999"
                      ]
                    ]
                  ]
                ]
              ]
            ]
          ]
        ]
      ]
    ]
  ]
  "idiomaDefecto" => "en"
  "url" => "/15782190/0000011000000006/v1_201907040838/S1578219019300356/v1_201907040838/en/main.assets"
  "Apartado" => array:4 [
    "identificador" => "6154"
    "tipo" => "SECCION"
    "en" => array:2 [
      "titulo" => "Case for Diagnosis"
      "idiomaDefecto" => true
    ]
    "idiomaDefecto" => "en"
  ]
  "PDF" => "https://static.elsevier.es/multimedia/15782190/0000011000000006/v1_201907040838/S1578219019300356/v1_201907040838/en/main.pdf?idApp=UINPBA000044&text.app=https://actasdermo.org/"
  "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219019300356?idApp=UINPBA000044"
]
Compartir
Información de la revista

Estadísticas

Siga este enlace para acceder al texto completo del artículo

Case for Diagnosis
Fast-Growing Occipital Tumor
Tumoración occipital de rápido crecimiento
E. Varas-Meis
Autor para correspondencia
edu.varas.meis@gmail.com

Corresponding author.
, C. Prada-García, P. Fernández-Canga, M.Á. Rodriguez-Prieto
Servicio de Dermatología, Complejo Asistencial Universitario de León, León, España
Leído
4038
Veces
se ha leído el artículo
1568
Total PDF
2470
Total HTML
Compartir estadísticas
 array:24 [
  "pii" => "S1578219019300356"
  "issn" => "15782190"
  "doi" => "10.1016/j.adengl.2019.02.003"
  "estado" => "S300"
  "fechaPublicacion" => "2019-07-01"
  "aid" => "2069"
  "copyright" => "Elsevier Espa&#241;a&#44; S&#46;L&#46;U&#46; and AEDV"
  "copyrightAnyo" => "2018"
  "documento" => "simple-article"
  "crossmark" => 1
  "subdocumento" => "crp"
  "cita" => "Actas Dermosifiliogr. 2019;110:497-8"
  "abierto" => array:3 [
    "ES" => true
    "ES2" => true
    "LATM" => true
  ]
  "gratuito" => true
  "lecturas" => array:2 [
    "total" => 2
    "formatos" => array:2 [
      "HTML" => 1
      "PDF" => 1
    ]
  ]
  "Traduccion" => array:1 [
    "es" => array:19 [
      "pii" => "S0001731018304356"
      "issn" => "00017310"
      "doi" => "10.1016/j.ad.2017.11.025"
      "estado" => "S300"
      "fechaPublicacion" => "2019-07-01"
      "aid" => "2069"
      "copyright" => "AEDV"
      "documento" => "simple-article"
      "crossmark" => 1
      "subdocumento" => "crp"
      "cita" => "Actas Dermosifiliogr. 2019;110:497-8"
      "abierto" => array:3 [
        "ES" => true
        "ES2" => true
        "LATM" => true
      ]
      "gratuito" => true
      "lecturas" => array:2 [
        "total" => 318
        "formatos" => array:2 [
          "HTML" => 242
          "PDF" => 76
        ]
      ]
      "es" => array:11 [
        "idiomaDefecto" => true
        "cabecera" => "<span class="elsevierStyleTextfn">Casos para el diagn&#243;stico</span>"
        "titulo" => "Tumoraci&#243;n occipital de r&#225;pido crecimiento"
        "tienePdf" => "es"
        "tieneTextoCompleto" => "es"
        "paginas" => array:1 [
          0 => array:2 [
            "paginaInicial" => "497"
            "paginaFinal" => "498"
          ]
        ]
        "titulosAlternativos" => array:1 [
          "en" => array:1 [
            "titulo" => "Fast-Growing Occipital Tumor"
          ]
        ]
        "contieneTextoCompleto" => array:1 [
          "es" => true
        ]
        "contienePdf" => array:1 [
          "es" => true
        ]
        "resumenGrafico" => array:2 [
          "original" => 0
          "multimedia" => array:7 [
            "identificador" => "fig0015"
            "etiqueta" => "Figura 3"
            "tipo" => "MULTIMEDIAFIGURA"
            "mostrarFloat" => true
            "mostrarDisplay" => false
            "figura" => array:1 [
              0 => array:4 [
                "imagen" => "gr3.jpeg"
                "Alto" => 498
                "Ancho" => 900
                "Tamanyo" => 226829
              ]
            ]
            "descripcion" => array:1 [
              "es" => "<p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Hematoxilina-eosina &#215;4&#46;</p>"
            ]
          ]
        ]
        "autores" => array:1 [
          0 => array:2 [
            "autoresLista" => "E&#46; Varas-Meis, C&#46; Prada-Garc&#237;a, P&#46; Fern&#225;ndez-Canga, M&#46;&#193;&#46; Rodriguez-Prieto"
            "autores" => array:4 [
              0 => array:2 [
                "nombre" => "E&#46;"
                "apellidos" => "Varas-Meis"
              ]
              1 => array:2 [
                "nombre" => "C&#46;"
                "apellidos" => "Prada-Garc&#237;a"
              ]
              2 => array:2 [
                "nombre" => "P&#46;"
                "apellidos" => "Fern&#225;ndez-Canga"
              ]
              3 => array:2 [
                "nombre" => "M&#46;&#193;&#46;"
                "apellidos" => "Rodriguez-Prieto"
              ]
            ]
          ]
        ]
      ]
      "idiomaDefecto" => "es"
      "Traduccion" => array:1 [
        "en" => array:9 [
          "pii" => "S1578219019300356"
          "doi" => "10.1016/j.adengl.2019.02.003"
          "estado" => "S300"
          "subdocumento" => ""
          "abierto" => array:3 [
            "ES" => true
            "ES2" => true
            "LATM" => true
          ]
          "gratuito" => true
          "lecturas" => array:1 [
            "total" => 0
          ]
          "idiomaDefecto" => "en"
          "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219019300356?idApp=UINPBA000044"
        ]
      ]
      "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0001731018304356?idApp=UINPBA000044"
      "url" => "/00017310/0000011000000006/v1_201907020633/S0001731018304356/v1_201907020633/es/main.assets"
    ]
  ]
  "itemSiguiente" => array:19 [
    "pii" => "S1578219019301660"
    "issn" => "15782190"
    "doi" => "10.1016/j.adengl.2017.12.027"
    "estado" => "S300"
    "fechaPublicacion" => "2019-07-01"
    "aid" => "2007"
    "copyright" => "Elsevier Espa&#241;a&#44; S&#46;L&#46;U&#46; and AEDV"
    "documento" => "article"
    "crossmark" => 1
    "subdocumento" => "sco"
    "cita" => "Actas Dermosifiliogr. 2019;110:499-500"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:1 [
      "total" => 0
    ]
    "en" => array:10 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">Resident&#39;s Forum</span>"
      "titulo" => "RF - Epidermal Growth Factor Receptor Inhibitors and Skin Toxicity&#58; The Search for a Management Protocol"
      "tienePdf" => "en"
      "tieneTextoCompleto" => "en"
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "499"
          "paginaFinal" => "500"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "es" => array:1 [
          "titulo" => "FR - Inhibidores del factor de crecimiento epid&#233;rmico y toxicidad cut&#225;nea&#58; en busca de un protocolo de manejo"
        ]
      ]
      "contieneTextoCompleto" => array:1 [
        "en" => true
      ]
      "contienePdf" => array:1 [
        "en" => true
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "J&#46;J&#46; Andr&#233;s-Lencina, R&#46; Arag&#243;n-Miguel, A&#46; Calleja-Algarra"
          "autores" => array:3 [
            0 => array:2 [
              "nombre" => "J&#46;J&#46;"
              "apellidos" => "Andr&#233;s-Lencina"
            ]
            1 => array:2 [
              "nombre" => "R&#46;"
              "apellidos" => "Arag&#243;n-Miguel"
            ]
            2 => array:2 [
              "nombre" => "A&#46;"
              "apellidos" => "Calleja-Algarra"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "en"
    "Traduccion" => array:1 [
      "es" => array:9 [
        "pii" => "S0001731018302928"
        "doi" => "10.1016/j.ad.2017.12.019"
        "estado" => "S300"
        "subdocumento" => ""
        "abierto" => array:3 [
          "ES" => true
          "ES2" => true
          "LATM" => true
        ]
        "gratuito" => true
        "lecturas" => array:1 [
          "total" => 0
        ]
        "idiomaDefecto" => "es"
        "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0001731018302928?idApp=UINPBA000044"
      ]
    ]
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219019301660?idApp=UINPBA000044"
    "url" => "/15782190/0000011000000006/v1_201907040838/S1578219019301660/v1_201907040838/en/main.assets"
  ]
  "itemAnterior" => array:18 [
    "pii" => "S1578219019300381"
    "issn" => "15782190"
    "doi" => "10.1016/j.adengl.2019.02.006"
    "estado" => "S300"
    "fechaPublicacion" => "2019-07-01"
    "aid" => "2118"
    "documento" => "simple-article"
    "crossmark" => 1
    "subdocumento" => "crp"
    "cita" => "Actas Dermosifiliogr. 2019;110:495-6"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:1 [
      "total" => 0
    ]
    "en" => array:11 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">Case for Diagnosis</span>"
      "titulo" => "Progressive skin ulcers in extremities"
      "tienePdf" => "en"
      "tieneTextoCompleto" => "en"
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "495"
          "paginaFinal" => "496"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "es" => array:1 [
          "titulo" => "&#218;lceras progresivas localizadas en las extremidades"
        ]
      ]
      "contieneTextoCompleto" => array:1 [
        "en" => true
      ]
      "contienePdf" => array:1 [
        "en" => true
      ]
      "resumenGrafico" => array:2 [
        "original" => 0
        "multimedia" => array:6 [
          "identificador" => "fig0005"
          "etiqueta" => "Figure 1"
          "tipo" => "MULTIMEDIAFIGURA"
          "mostrarFloat" => true
          "mostrarDisplay" => false
          "figura" => array:1 [
            0 => array:4 [
              "imagen" => "gr1.jpeg"
              "Alto" => 520
              "Ancho" => 500
              "Tamanyo" => 41737
            ]
          ]
        ]
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "S&#46; Castillo-Loaiza, C&#46;J&#46; D&#237;az, L&#46;F&#46; Cardenas"
          "autores" => array:3 [
            0 => array:2 [
              "nombre" => "S&#46;"
              "apellidos" => "Castillo-Loaiza"
            ]
            1 => array:2 [
              "nombre" => "C&#46;J&#46;"
              "apellidos" => "D&#237;az"
            ]
            2 => array:2 [
              "nombre" => "L&#46;F&#46;"
              "apellidos" => "Cardenas"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "en"
    "Traduccion" => array:1 [
      "es" => array:9 [
        "pii" => "S0001731018305428"
        "doi" => "10.1016/j.ad.2018.01.017"
        "estado" => "S300"
        "subdocumento" => ""
        "abierto" => array:3 [
          "ES" => true
          "ES2" => true
          "LATM" => true
        ]
        "gratuito" => true
        "lecturas" => array:1 [
          "total" => 0
        ]
        "idiomaDefecto" => "es"
        "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0001731018305428?idApp=UINPBA000044"
      ]
    ]
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219019300381?idApp=UINPBA000044"
    "url" => "/15782190/0000011000000006/v1_201907040838/S1578219019300381/v1_201907040838/en/main.assets"
  ]
  "en" => array:17 [
    "idiomaDefecto" => true
    "cabecera" => "<span class="elsevierStyleTextfn">Case for Diagnosis</span>"
    "titulo" => "Fast-Growing Occipital Tumor"
    "tieneTextoCompleto" => true
    "paginas" => array:1 [
      0 => array:2 [
        "paginaInicial" => "497"
        "paginaFinal" => "498"
      ]
    ]
    "autores" => array:1 [
      0 => array:4 [
        "autoresLista" => "E&#46; Varas-Meis, C&#46; Prada-Garc&#237;a, P&#46; Fern&#225;ndez-Canga, M&#46;&#193;&#46; Rodriguez-Prieto"
        "autores" => array:4 [
          0 => array:4 [
            "nombre" => "E&#46;"
            "apellidos" => "Varas-Meis"
            "email" => array:1 [
              0 => "edu.varas.meis@gmail.com"
            ]
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">&#42;</span>"
                "identificador" => "cor0005"
              ]
            ]
          ]
          1 => array:2 [
            "nombre" => "C&#46;"
            "apellidos" => "Prada-Garc&#237;a"
          ]
          2 => array:2 [
            "nombre" => "P&#46;"
            "apellidos" => "Fern&#225;ndez-Canga"
          ]
          3 => array:2 [
            "nombre" => "M&#46;&#193;&#46;"
            "apellidos" => "Rodriguez-Prieto"
          ]
        ]
        "afiliaciones" => array:1 [
          0 => array:2 [
            "entidad" => "Servicio de Dermatolog&#237;a&#44; Complejo Asistencial Universitario de Le&#243;n&#44; Le&#243;n&#44; Espa&#241;a"
            "identificador" => "aff0005"
          ]
        ]
        "correspondencia" => array:1 [
          0 => array:3 [
            "identificador" => "cor0005"
            "etiqueta" => "&#8270;"
            "correspondencia" => "Corresponding author&#46;"
          ]
        ]
      ]
    ]
    "titulosAlternativos" => array:1 [
      "es" => array:1 [
        "titulo" => "Tumoraci&#243;n occipital de r&#225;pido crecimiento"
      ]
    ]
    "resumenGrafico" => array:2 [
      "original" => 0
      "multimedia" => array:7 [
        "identificador" => "fig0010"
        "etiqueta" => "Figure 2"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr2.jpeg"
            "Alto" => 459
            "Ancho" => 900
            "Tamanyo" => 202518
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Hematoxylin-eosin&#44; original magnification &#215;2&#46;</p>"
        ]
      ]
    ]
    "textoCompleto" => "<span class="elsevierStyleSections"><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0005">Medical History</span><p id="par0005" class="elsevierStylePara elsevierViewall">The patient was an 89-year-old woman who had been diagnosed 40 years earlier with multiple trichilemmal cysts&#44; and had no other medical history of interest&#46; She was referred to our clinic for an asymptomatic ulcerated lesion on the scalp that had appeared 2 months earlier&#46;</p></span><span id="sec0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0010">Physical Examination</span><p id="par0010" class="elsevierStylePara elsevierViewall">Physical examination revealed a solid-to-keratotic&#44; exophytic&#44; crateriform tumor of 4&#160;cm in diameter located in the occipital region and adhered to deep planes &#40;<a class="elsevierStyleCrossRef" href="#fig0005">Fig&#46; 1</a>&#41;&#46; The lesion was surrounded by multiple previously diagnosed trichilemmal cysts&#46; No other lesions were detected&#44; and lymph node enlargement was absent&#46;</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia></span><span id="sec0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0015">Histopathology</span><p id="par0015" class="elsevierStylePara elsevierViewall">The lesion was excised for pathological examination&#44; which revealed a well-delimited and unencapsulated epithelial proliferation located in the superficial reticular dermis with an endophytic and exophytic growth pattern&#46; This hyperplasia consisted of multiple partially cystic epithelial cords and lobules&#44; with peripheral palisading and central trichilemmal keratinization&#46; More detailed analysis revealed mild-to-moderate cellular atypia&#44; with no aberrant mitoses or areas of necrosis &#40;<a class="elsevierStyleCrossRefs" href="#fig0010">Figs&#46; 2 and 3</a>&#41;&#46;</p><elsevierMultimedia ident="fig0010"></elsevierMultimedia><elsevierMultimedia ident="fig0015"></elsevierMultimedia><p id="par0020" class="elsevierStylePara elsevierViewall">What Is Your Diagnosis&#63;</p></span><span id="sec0020" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0020">Diagnosis</span><p id="par0025" class="elsevierStylePara elsevierViewall">Proliferating pilar tumor &#40;PPT&#41;&#46;</p></span><span id="sec0025" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0025">Course</span><p id="par0030" class="elsevierStylePara elsevierViewall">The patient showed no recurrence after 6 months of follow-up&#46;</p></span><span id="sec0030" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0030">Comment</span><p id="par0035" class="elsevierStylePara elsevierViewall">PPT is an adnexal tumor derived from the external radicular membrane of the hair follicle&#46;<a class="elsevierStyleCrossRef" href="#bib0050"><span class="elsevierStyleSup">1</span></a> It usually presents as an exophytic scalp tumor&#44; in many cases with ulceration&#44; bleeding&#44; and&#47;or superinfection&#44; and typically affects women aged 40 years and older&#46; However&#44; cases involving tumors in atypical locations&#44; including the thorax&#44; back&#44; buttock&#44; nose&#44; and vulva&#44; have also been described&#46;<a class="elsevierStyleCrossRef" href="#bib0055"><span class="elsevierStyleSup">2</span></a> In most cases PPT arises from a pre-existing trichilemmal cyst&#44; although de novo forms&#44; which develop in the absence of pre-existing lesions&#44; are also described&#46;<a class="elsevierStyleCrossRef" href="#bib0060"><span class="elsevierStyleSup">3</span></a></p><p id="par0040" class="elsevierStylePara elsevierViewall">Histologically&#44; PPT is characterized by hyperplasia consisting of solid or partially cystic epithelial cords or lobules&#44; with peripheral palisading and trichilemmal keratinization&#46;<a class="elsevierStyleCrossRefs" href="#bib0050"><span class="elsevierStyleSup">1&#8211;3</span></a> Areas of necrosis&#44; anaplastic cells&#44; and aberrant mitoses are common&#46;<a class="elsevierStyleCrossRefs" href="#bib0060"><span class="elsevierStyleSup">3&#44;4</span></a> PPT can be associated with foreign body reaction&#44; dystrophic calcification&#44; squamous eddies&#44; and areas of vacuolization or dyskeratosis&#46;<a class="elsevierStyleCrossRefs" href="#bib0055"><span class="elsevierStyleSup">2&#44;4</span></a></p><p id="par0045" class="elsevierStylePara elsevierViewall">When differentiating PPT from squamous cell carcinoma&#44; foci of trichilemmal keratinization&#44; sharp delimitation&#44; areas of calcification&#44; and the absence of premalignant epidermal lesions help orient the diagnosis towards PPT&#46;<a class="elsevierStyleCrossRef" href="#bib0070"><span class="elsevierStyleSup">5</span></a> The differential diagnosis should also include sebaceous carcinoma&#44; clear cell hidradenocarcinoma&#44; pilomatrixoma&#44; and trichoblastoma&#46;<a class="elsevierStyleCrossRefs" href="#bib0075"><span class="elsevierStyleSup">6&#44;7</span></a></p><p id="par0050" class="elsevierStylePara elsevierViewall">PPT follows an unpredictable course and lies on a spectrum ranging from benign trichilemmal cysts with minimal epithelial proliferation to malignant PPT with local invasion&#44; a tendency to recur&#44; and occasional distant metastases&#46;<a class="elsevierStyleCrossRefs" href="#bib0060"><span class="elsevierStyleSup">3&#44;5&#44;8</span></a> An infiltrative pattern with cellular anaplasia&#44; atypical mitoses&#44; and&#47;or areas of necrosis are considered histological markers of poor prognosis&#46;<a class="elsevierStyleCrossRef" href="#bib0055"><span class="elsevierStyleSup">2</span></a> The treatment of choice is exeresis with wide margins &#40;1&#8211;2&#160;cm&#41; or Mohs micrographic surgery&#44; although a good therapeutic response has also been reported in patients treated with radiotherapy&#46;<a class="elsevierStyleCrossRefs" href="#bib0085"><span class="elsevierStyleSup">8&#44;9</span></a></p><p id="par0055" class="elsevierStylePara elsevierViewall">In conclusion&#44; we describe a representative case of a little-known adnexal lesion&#44; knowledge of which is necessary in order to select the appropriate therapeutic measures&#46;</p></span><span id="sec0035" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0035">Conflicts of Interest</span><p id="par0060" class="elsevierStylePara elsevierViewall">The authors declare that they have no conflicts of interest&#46;</p></span></span>"
    "textoCompletoSecciones" => array:1 [
      "secciones" => array:8 [
        0 => array:2 [
          "identificador" => "sec0005"
          "titulo" => "Medical History"
        ]
        1 => array:2 [
          "identificador" => "sec0010"
          "titulo" => "Physical Examination"
        ]
        2 => array:2 [
          "identificador" => "sec0015"
          "titulo" => "Histopathology"
        ]
        3 => array:2 [
          "identificador" => "sec0020"
          "titulo" => "Diagnosis"
        ]
        4 => array:2 [
          "identificador" => "sec0025"
          "titulo" => "Course"
        ]
        5 => array:2 [
          "identificador" => "sec0030"
          "titulo" => "Comment"
        ]
        6 => array:2 [
          "identificador" => "sec0035"
          "titulo" => "Conflicts of Interest"
        ]
        7 => array:1 [
          "titulo" => "References"
        ]
      ]
    ]
    "pdfFichero" => "main.pdf"
    "tienePdf" => true
    "fechaRecibido" => "2017-07-11"
    "fechaAceptado" => "2017-11-23"
    "NotaPie" => array:1 [
      0 => array:2 [
        "etiqueta" => "&#9734;"
        "nota" => "<p class="elsevierStyleNotepara" id="npar0005">Please cite this article as&#58; Varas-Meis E&#44; Prada-Garc&#237;a C&#44; Fern&#225;ndez-Canga P&#44; Rodriguez-Prieto M&#193;&#46; Tumoraci&#243;n occipital de r&#225;pido crecimiento&#46; Actas Dermosifiliogr&#46; 2019&#59;110&#58;497&#8211;498&#46;</p>"
      ]
    ]
    "multimedia" => array:3 [
      0 => array:6 [
        "identificador" => "fig0005"
        "etiqueta" => "Figure 1"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr1.jpeg"
            "Alto" => 647
            "Ancho" => 750
            "Tamanyo" => 63727
          ]
        ]
      ]
      1 => array:7 [
        "identificador" => "fig0010"
        "etiqueta" => "Figure 2"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr2.jpeg"
            "Alto" => 459
            "Ancho" => 900
            "Tamanyo" => 202518
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Hematoxylin-eosin&#44; original magnification &#215;2&#46;</p>"
        ]
      ]
      2 => array:7 [
        "identificador" => "fig0015"
        "etiqueta" => "Figure 3"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr3.jpeg"
            "Alto" => 498
            "Ancho" => 900
            "Tamanyo" => 226829
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Hematoxylin-eosin&#44; original magnification &#215;4&#46;</p>"
        ]
      ]
    ]
    "bibliografia" => array:2 [
      "titulo" => "References"
      "seccion" => array:1 [
        0 => array:2 [
          "identificador" => "bibs0015"
          "bibliografiaReferencia" => array:9 [
            0 => array:3 [
              "identificador" => "bib0050"
              "etiqueta" => "1"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Proliferating trichilemmal tumors&#58; Clinicopathologic evaluation is a guide to biologic behavior"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "A&#46;L&#46; Folpe"
                            1 => "A&#46;K&#46; Reisenauer"
                            2 => "T&#46; Mentzel"
                            3 => "A&#46; R&#252;tten"
                            4 => "A&#46;R&#46; Solomon"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "J Cutan Pathol"
                        "fecha" => "2003"
                        "volumen" => "30"
                        "paginaInicial" => "492"
                        "paginaFinal" => "498"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            1 => array:3 [
              "identificador" => "bib0055"
              "etiqueta" => "2"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Proliferating pilar tumors&#58; A clinicopathologic study of 76 cases with a proposal for definition of benign and malignant variants"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "J&#46; Ye"
                            1 => "O&#46; Nappi"
                            2 => "P&#46;E&#46; Swanson"
                            3 => "J&#46;W&#46; Patterson"
                            4 => "M&#46;R&#46; Wick"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Am J Clin Pathol"
                        "fecha" => "2004"
                        "volumen" => "122"
                        "paginaInicial" => "566"
                        "paginaFinal" => "574"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            2 => array:3 [
              "identificador" => "bib0060"
              "etiqueta" => "3"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Proliferating trichilemmal tumors&#58; A review of the literature"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "A&#46;K&#46; Satyaprakash"
                            1 => "D&#46;J&#46; Sheehan"
                            2 => "O&#46;P&#46; Sang&#252;eza"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Dermatol Surg"
                        "fecha" => "2007"
                        "volumen" => "33"
                        "paginaInicial" => "1102"
                        "paginaFinal" => "1108"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            3 => array:3 [
              "identificador" => "bib0065"
              "etiqueta" => "4"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Proliferating epithelial cysts&#46; Clinicopathological analysis of 96 cases"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "P&#46; Sau"
                            1 => "J&#46;H&#46; Graham"
                            2 => "E&#46;B&#46; Helwig"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "J Cutan Pathol"
                        "fecha" => "1995"
                        "volumen" => "22"
                        "paginaInicial" => "394"
                        "paginaFinal" => "406"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8594071"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            4 => array:3 [
              "identificador" => "bib0070"
              "etiqueta" => "5"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Proliferating trichilemmal cyst&#58; A simulant of squamous cell carcinoma"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "M&#46;H&#46; Brownstein"
                            1 => "D&#46;J&#46; Arluk"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Cancer"
                        "fecha" => "1981"
                        "volumen" => "48"
                        "paginaInicial" => "1207"
                        "paginaFinal" => "1214"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            5 => array:3 [
              "identificador" => "bib0075"
              "etiqueta" => "6"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Malignant pilar tumor of the scalp&#58; A case report and review of literature"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:7 [
                            0 => "M&#46; Siddha"
                            1 => "A&#46; Budrukkar"
                            2 => "T&#46; Shet"
                            3 => "M&#46; Deshpande"
                            4 => "A&#46; Basu"
                            5 => "N&#46; Patil"
                            6 => "R&#46; Bhalavat"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "J Cancer Res Ther"
                        "fecha" => "2007"
                        "volumen" => "3"
                        "paginaInicial" => "240"
                        "paginaFinal" => "243"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            6 => array:3 [
              "identificador" => "bib0080"
              "etiqueta" => "7"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Malignant Proliferating Trichilemmal cyst&#58; A case report with review of literature"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "P&#46;K&#46; Garg"
                            1 => "A&#46; Dangi"
                            2 => "N&#46; Khurana"
                            3 => "N&#46;S&#46; Hadke"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Malays J Pathol"
                        "fecha" => "2009"
                        "volumen" => "31"
                        "paginaInicial" => "71"
                        "paginaFinal" => "76"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            7 => array:3 [
              "identificador" => "bib0085"
              "etiqueta" => "8"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Malignant proliferating trichilemmal tumor treated with Mohs surgery&#58; Proposed protocol for diagnostic work-up and treatment"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "D&#46;R&#46; Fieleke"
                            1 => "G&#46;D&#46; Goldstein"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Dermatol Surg"
                        "fecha" => "2015"
                        "volumen" => "41"
                        "paginaInicial" => "292"
                        "paginaFinal" => "294"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            8 => array:3 [
              "identificador" => "bib0090"
              "etiqueta" => "9"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Malignant proliferating trichilemmal tumor treated with radical radiotherapy&#58; A case report and literature review"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "D&#46; Sutherland"
                            1 => "K&#46; Roth"
                            2 => "E&#46; Yu"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:4 [
                        "tituloSerie" => "Cureus"
                        "fecha" => "2017"
                        "volumen" => "9"
                        "paginaInicial" => "e999"
                      ]
                    ]
                  ]
                ]
              ]
            ]
          ]
        ]
      ]
    ]
  ]
  "idiomaDefecto" => "en"
  "url" => "/15782190/0000011000000006/v1_201907040838/S1578219019300356/v1_201907040838/en/main.assets"
  "Apartado" => array:4 [
    "identificador" => "6154"
    "tipo" => "SECCION"
    "en" => array:2 [
      "titulo" => "Case for Diagnosis"
      "idiomaDefecto" => true
    ]
    "idiomaDefecto" => "en"
  ]
  "PDF" => "https://static.elsevier.es/multimedia/15782190/0000011000000006/v1_201907040838/S1578219019300356/v1_201907040838/en/main.pdf?idApp=UINPBA000044&text.app=https://actasdermo.org/"
  "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219019300356?idApp=UINPBA000044"
]
Información del artículo
ISSN: 15782190
Idioma original: Inglés
Datos actualizados diariamente
año/Mes Html Pdf Total
2024 Noviembre 10 12 22
2024 Octubre 88 38 126
2024 Septiembre 121 23 144
2024 Agosto 105 74 179
2024 Julio 81 37 118
2024 Junio 90 42 132
2024 Mayo 78 35 113
2024 Abril 102 26 128
2024 Marzo 85 25 110
2024 Febrero 76 41 117
2024 Enero 69 31 100
2023 Diciembre 61 21 82
2023 Noviembre 63 23 86
2023 Octubre 66 19 85
2023 Septiembre 45 27 72
2023 Agosto 45 19 64
2023 Julio 42 32 74
2023 Junio 47 19 66
2023 Mayo 48 27 75
2023 Abril 38 16 54
2023 Marzo 49 22 71
2023 Febrero 53 27 80
2023 Enero 35 28 63
2022 Diciembre 57 36 93
2022 Noviembre 37 29 66
2022 Octubre 29 21 50
2022 Septiembre 20 36 56
2022 Agosto 29 32 61
2022 Julio 27 42 69
2022 Junio 38 31 69
2022 Mayo 21 33 54
2022 Abril 38 32 70
2022 Marzo 41 41 82
2022 Febrero 23 19 42
2022 Enero 25 31 56
2021 Diciembre 31 28 59
2021 Noviembre 36 39 75
2021 Octubre 36 53 89
2021 Septiembre 32 33 65
2021 Agosto 24 30 54
2021 Julio 17 32 49
2021 Junio 15 31 46
2021 Mayo 24 33 57
2021 Abril 44 60 104
2021 Marzo 59 13 72
2021 Febrero 65 30 95
2021 Enero 42 12 54
2020 Diciembre 32 14 46
2020 Noviembre 12 14 26
2020 Octubre 15 16 31
2020 Septiembre 20 12 32
2020 Agosto 11 12 23
2020 Julio 7 11 18
2020 Junio 22 18 40
2020 Mayo 17 12 29
2020 Abril 10 10 20
2020 Marzo 15 5 20
2020 Febrero 1 2 3
2019 Mayo 1 1 2
Mostrar todo

Siga este enlace para acceder al texto completo del artículo

Idiomas
Actas Dermo-Sifiliográficas
es en

¿Es usted profesional sanitario apto para prescribir o dispensar medicamentos?

Are you a health professional able to prescribe or dispense drugs?