Estadísticas

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    "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">The BIOBADADERM registry prospectively collects demographic data&#44; clinical management data&#44; and data on adverse events from 14 Spanish hospitals under conditions of daily clinical practice&#46; Therefore&#44; it is extremely useful for determining the therapeutic management of moderate to severe psoriasis in Spain&#46;</p><p id="par0010" class="elsevierStylePara elsevierViewall">In this article from the BIOBADADERM study group&#44;<a class="elsevierStyleCrossRef" href="#bib0005"><span class="elsevierStyleSup">1</span></a> the authors describe the clinical characteristics of patients who receive biologic drugs as first-line therapy in daily clinical practice&#46; These are the first published data of this type&#44; since&#44; according to the summary of product characteristics&#44; biologic drugs are usually prescribed after classic systemic treatments&#46; Patients who receive biologics as first-line therapy more often have arterial hypertension&#44; diabetes mellitus&#44; chronic liver disease&#44; hepatitis C&#44; and HIV infection&#46; Therefore&#44; it seems that the main reason classic systemic options are ruled out as first-line therapy is to avoid associated interactions and adverse effects&#46;</p><p id="par0015" class="elsevierStylePara elsevierViewall">In contrast&#44; there are no differences in clinical characteristics&#44; medical management&#44; or adverse effects between patients who receive biologics as first- or second-line therapy&#46;</p><p id="par0020" class="elsevierStylePara elsevierViewall">This study opens the debate on the advantages and disadvantages of biologic treatment as first-line systemic treatment before conventional therapy&#46;</p></span>"
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