se ha leído el artículo
array:23 [ "pii" => "S1578219018302282" "issn" => "15782190" "doi" => "10.1016/j.adengl.2018.02.024" "estado" => "S300" "fechaPublicacion" => "2018-09-01" "aid" => "1952" "copyright" => "Elsevier España, S.L.U. and AEDV" "copyrightAnyo" => "2018" "documento" => "simple-article" "crossmark" => 1 "subdocumento" => "cor" "cita" => "Actas Dermosifiliogr. 2018;109:665-6" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:1 [ "total" => 0 ] "Traduccion" => array:1 [ "es" => array:19 [ "pii" => "S0001731018301777" "issn" => "00017310" "doi" => "10.1016/j.ad.2018.02.016" "estado" => "S300" "fechaPublicacion" => "2018-09-01" "aid" => "1952" "copyright" => "AEDV" "documento" => "simple-article" "crossmark" => 1 "subdocumento" => "cor" "cita" => "Actas Dermosifiliogr. 2018;109:665-6" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 79 "formatos" => array:2 [ "HTML" => 56 "PDF" => 23 ] ] "es" => array:10 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">CARTA AL DIRECTOR</span>" "titulo" => "Verrugas genitales, linfangioma y tratamiento con imiquimod" "tienePdf" => "es" "tieneTextoCompleto" => "es" "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "665" "paginaFinal" => "666" ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Genital Warts, Lymphangioma, and Treatment with Imiquimod" ] ] "contieneTextoCompleto" => array:1 [ "es" => true ] "contienePdf" => array:1 [ "es" => true ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "B. Monteagudo, O. Figueroa, A. Varela-Veiga, O. Suárez-Amor" "autores" => array:4 [ 0 => array:2 [ "nombre" => "B." "apellidos" => "Monteagudo" ] 1 => array:2 [ "nombre" => "O." "apellidos" => "Figueroa" ] 2 => array:2 [ "nombre" => "A." "apellidos" => "Varela-Veiga" ] 3 => array:2 [ "nombre" => "O." "apellidos" => "Suárez-Amor" ] ] ] ] ] "idiomaDefecto" => "es" "Traduccion" => array:1 [ "en" => array:9 [ "pii" => "S1578219018302282" "doi" => "10.1016/j.adengl.2018.02.024" "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:1 [ "total" => 0 ] "idiomaDefecto" => "en" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219018302282?idApp=UINPBA000044" ] ] "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0001731018301777?idApp=UINPBA000044" "url" => "/00017310/0000010900000007/v1_201809020415/S0001731018301777/v1_201809020415/es/main.assets" ] ] "itemAnterior" => array:19 [ "pii" => "S1578219018302270" "issn" => "15782190" "doi" => "10.1016/j.adengl.2018.06.016" "estado" => "S300" "fechaPublicacion" => "2018-09-01" "aid" => "1951" "copyright" => "Elsevier España, S.L.U. and AEDV" "documento" => "simple-article" "crossmark" => 1 "subdocumento" => "cor" "cita" => "Actas Dermosifiliogr. 2018;109:664-5" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 1 "HTML" => 1 ] "en" => array:11 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Letter to the Editor</span>" "titulo" => "Genital Warts, Lymphangioma, and Treatment with Imiquimod" "tienePdf" => "en" "tieneTextoCompleto" => "en" "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "664" "paginaFinal" => "665" ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Verrugas genitales, linfangioma y tratamiento con imiquimod" ] ] "contieneTextoCompleto" => array:1 [ "en" => true ] "contienePdf" => array:1 [ "en" => true ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:7 [ "identificador" => "fig0005" "etiqueta" => "Figure 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 678 "Ancho" => 900 "Tamanyo" => 86744 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Clinical appearance of vulvar lesions following surgery and electrocoagulation.</p>" ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "L. Padilla-España, J.B. Repiso-Jiménez, J.F. Millán-Cayetano" "autores" => array:3 [ 0 => array:2 [ "nombre" => "L." "apellidos" => "Padilla-España" ] 1 => array:2 [ "nombre" => "J.B." "apellidos" => "Repiso-Jiménez" ] 2 => array:2 [ "nombre" => "J.F." "apellidos" => "Millán-Cayetano" ] ] ] ] ] "idiomaDefecto" => "en" "Traduccion" => array:1 [ "es" => array:9 [ "pii" => "S0001731018301765" "doi" => "10.1016/j.ad.2018.03.011" "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:1 [ "total" => 0 ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0001731018301765?idApp=UINPBA000044" ] ] "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219018302270?idApp=UINPBA000044" "url" => "/15782190/0000010900000007/v1_201809020417/S1578219018302270/v1_201809020417/en/main.assets" ] "en" => array:13 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Letter to the Editor</span>" "titulo" => "Genital Warts, Lymphangioma, and Treatment with Imiquimod" "tieneTextoCompleto" => true "saludo" => "<span class="elsevierStyleItalic">Dear Editor:</span>" "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "665" "paginaFinal" => "666" ] ] "autores" => array:1 [ 0 => array:4 [ "autoresLista" => "B. Monteagudo, O. Figueroa, A. Varela-Veiga, O. Suárez-Amor" "autores" => array:4 [ 0 => array:4 [ "nombre" => "B." "apellidos" => "Monteagudo" "email" => array:1 [ 0 => "benigno.monteagudo.sanchez@sergas.es" ] "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">*</span>" "identificador" => "cor0005" ] ] ] 1 => array:2 [ "nombre" => "O." "apellidos" => "Figueroa" ] 2 => array:2 [ "nombre" => "A." "apellidos" => "Varela-Veiga" ] 3 => array:2 [ "nombre" => "O." "apellidos" => "Suárez-Amor" ] ] "afiliaciones" => array:1 [ 0 => array:2 [ "entidad" => "Servicio de Dermatología, Complejo Hospitalario Universitario de Ferrol, Xerencia de Xestión Integrada de Ferrol, SERGAS, Ferrol, A Coruña, Spain" "identificador" => "aff0005" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "⁎" "correspondencia" => "Corresponding author." ] ] ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Verrugas genitales, linfangioma y tratamiento con imiquimod" ] ] "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">We have read with interest the article “Pseudoverrucous Lesions of Recent Appearance on the Vulva” in which the authors report the case of an adult woman with acquired vulvar lymphangioma.<a class="elsevierStyleCrossRef" href="#bib0040"><span class="elsevierStyleSup">1</span></a> In their article they stress the need to correctly diagnose the condition and to avoid confusion with other disorders, such as genital warts, in order to identify the appropriate treatment and the underlying cause (lymphadenectomy, radiation therapy for pelvic carcinoma, Crohn disease, or tuberculosis).<a class="elsevierStyleCrossRefs" href="#bib0040"><span class="elsevierStyleSup">1,2</span></a></p><p id="par0010" class="elsevierStylePara elsevierViewall">In the clinical history, the authors note as an interesting fact that the patient had been diagnosed 5 years earlier with genital warts, which were treated successfully with imiquimod 5% cream. In our opinion, the value of the article would have been even greater if the authors had analyzed the possible role of imiquimod therapy in the pathogenesis of the lymphangioma.</p><p id="par0015" class="elsevierStylePara elsevierViewall">It is possible that the imiquimod therapy may, while resolving the infectious process, have given rise to lymphedema and that this condition then favored the development of the lymphangioma. Edema and lymphedema are adverse effects reported to be associated with imiquimod treatment. These conditions may resolve rapidly (for example, in the genital area),<a class="elsevierStyleCrossRef" href="#bib0050"><span class="elsevierStyleSup">3</span></a> or persist for months or even years (reported in 1 case on the cheek following prolonged use of imiquimod to treat lentigo maligno melanoma).<a class="elsevierStyleCrossRef" href="#bib0055"><span class="elsevierStyleSup">4</span></a> The influence of lymphedema on the development of lymphangiomas is also well known.<a class="elsevierStyleCrossRefs" href="#bib0045"><span class="elsevierStyleSup">2,5</span></a></p><p id="par0020" class="elsevierStylePara elsevierViewall">We do not know whether the initial diagnosis of genital warts was confirmed by histopathology. If that diagnosis was not confirmed, it is possible that the earlier lesions were, in fact, lymphangioma. In that event, the interest of the case would be in the partial response to treatment with imiquimod. Imiquimod has been shown to be an effective therapy in some cases of lymphangioma circumscriptum. Occasionally, as occurred in this case, the lesion recurs months later.<a class="elsevierStyleCrossRef" href="#bib0065"><span class="elsevierStyleSup">6</span></a> It is thought that imiquimod has an antiangiogenic effect and induces apoptosis of the tumor cells.<a class="elsevierStyleCrossRefs" href="#bib0065"><span class="elsevierStyleSup">6,7</span></a></p><p id="par0025" class="elsevierStylePara elsevierViewall">In conclusion, we found this recent report of a cases of acquired lymphangioma circumscriptum very interesting. It would be important to know what imiquimod regimen was used and the duration of treatment, as this information could be used to hypothesize about the possible role of imiquimod in the development of the lymphangioma.</p></span>" "pdfFichero" => "main.pdf" "tienePdf" => true "NotaPie" => array:1 [ 0 => array:2 [ "etiqueta" => "☆" "nota" => "<p class="elsevierStyleNotepara" id="npar0005">Please cite this article as: Monteagudo B, Figueroa O, Varela-Veiga A, Suárez-Amor O. Verrugas genitales, linfangioma y tratamiento con imiquimod. Actas Dermosifiliogr. 2018;109:665–666.</p>" ] ] "bibliografia" => array:2 [ "titulo" => "References" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0015" "bibliografiaReferencia" => array:7 [ 0 => array:3 [ "identificador" => "bib0040" "etiqueta" => "1" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Lesiones seudoverrugosas vulvares de reciente aparición" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "L. Padilla-España" 1 => "J. Bosco Repiso-Jiménez" 2 => "C. Abitei" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/j.ad.2016.07.026" "Revista" => array:6 [ "tituloSerie" => "Actas Dermosifiliogr." "fecha" => "2018" "volumen" => "109" "paginaInicial" => "65" "paginaFinal" => "66" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/28283172" "web" => "Medline" ] ] ] ] ] ] ] ] 1 => array:3 [ "identificador" => "bib0045" "etiqueta" => "2" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Acquired lymphangiectasia (lymphangioma circumscriptum) of the vulva: Clinicopathologic study of 11 patients from a single institution and 67 from the literature" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "M.B. Chang" 1 => "C.C. Newman" 2 => "M.D. Davis" 3 => "J.S. Lehman" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1111/ijd.13264" "Revista" => array:6 [ "tituloSerie" => "Int J Dermatol." "fecha" => "2016" "volumen" => "55" "paginaInicial" => "e482" "paginaFinal" => "e487" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/26967121" "web" => "Medline" ] ] ] ] ] ] ] ] 2 => array:3 [ "identificador" => "bib0050" "etiqueta" => "3" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Dramatic saxophone penis as a result of topical imiquimod use" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "N.Y. Vidal" 1 => "R.S. Farah" 2 => "K.A. Wanat" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1001/jamadermatol.2014.1764" "Revista" => array:6 [ "tituloSerie" => "JAMA Dermatol." "fecha" => "2014" "volumen" => "150" "paginaInicial" => "1370" "paginaFinal" => "1371" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/25207721" "web" => "Medline" ] ] ] ] ] ] ] ] 3 => array:3 [ "identificador" => "bib0055" "etiqueta" => "4" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Lymphoedema in lentigo maligna patients treated with imiquimod, a long term adverse effect" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "D. Tio" 1 => "G. Kirtschig" 2 => "R. Hoekzema" 3 => "C. van Montfrans" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1111/bjd.16267" "Revista" => array:2 [ "tituloSerie" => "Br J Dermatol." "fecha" => "2017" ] ] ] ] ] ] 4 => array:3 [ "identificador" => "bib0060" "etiqueta" => "5" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Massive localized vulval lymphedema, with lymphangiomas of the labia majora, misdiagnosed as viral warts" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "N.J. Lawrance" 1 => "D. Mowatt" 2 => "J.A. Yell" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1097/LGT.0000000000000123" "Revista" => array:6 [ "tituloSerie" => "J Low Genit Tract Dis." "fecha" => "2015" "volumen" => "19" "paginaInicial" => "e64" "paginaFinal" => "e65" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/26247256" "web" => "Medline" ] ] ] ] ] ] ] ] 5 => array:3 [ "identificador" => "bib0065" "etiqueta" => "6" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Treatment of lymphangioma circumscriptum with topical imiquimod 5% cream" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "J.Y. Wang" 1 => "L.F. Liu" 2 => "X.H. Mao" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1111/j.1524-4725.2012.02528.x" "Revista" => array:6 [ "tituloSerie" => "Dermatol Surg." "fecha" => "2012" "volumen" => "38" "paginaInicial" => "1566" "paginaFinal" => "1569" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/22805499" "web" => "Medline" ] ] ] ] ] ] ] ] 6 => array:3 [ "identificador" => "bib0070" "etiqueta" => "7" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Preliminary communication: Imiquimod in mixed capillary/lymphatic malformation" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "M.R. Bongiorno" 1 => "M. Aricò" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1111/j.1529-8019.2008.00232.x" "Revista" => array:7 [ "tituloSerie" => "Dermatol Ther." "fecha" => "2008" "volumen" => "21" "numero" => "Suppl 2" "paginaInicial" => "S39" "paginaFinal" => "S42" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/18837733" "web" => "Medline" ] ] ] ] ] ] ] ] ] ] ] ] ] "idiomaDefecto" => "en" "url" => "/15782190/0000010900000007/v1_201809020417/S1578219018302282/v1_201809020417/en/main.assets" "Apartado" => array:4 [ "identificador" => "6208" "tipo" => "SECCION" "en" => array:2 [ "titulo" => "Letters to the Editor" "idiomaDefecto" => true ] "idiomaDefecto" => "en" ] "PDF" => "https://static.elsevier.es/multimedia/15782190/0000010900000007/v1_201809020417/S1578219018302282/v1_201809020417/en/main.pdf?idApp=UINPBA000044&text.app=https://actasdermo.org/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219018302282?idApp=UINPBA000044" ]
año/Mes | Html | Total | |
---|---|---|---|
2024 Noviembre | 7 | 9 | 16 |
2024 Octubre | 71 | 32 | 103 |
2024 Septiembre | 62 | 25 | 87 |
2024 Agosto | 82 | 40 | 122 |
2024 Julio | 67 | 26 | 93 |
2024 Junio | 75 | 20 | 95 |
2024 Mayo | 66 | 31 | 97 |
2024 Abril | 71 | 28 | 99 |
2024 Marzo | 62 | 26 | 88 |
2024 Febrero | 52 | 23 | 75 |
2024 Enero | 56 | 29 | 85 |
2023 Diciembre | 48 | 19 | 67 |
2023 Noviembre | 68 | 20 | 88 |
2023 Octubre | 59 | 20 | 79 |
2023 Septiembre | 54 | 33 | 87 |
2023 Agosto | 36 | 15 | 51 |
2023 Julio | 49 | 26 | 75 |
2023 Junio | 38 | 17 | 55 |
2023 Mayo | 41 | 23 | 64 |
2023 Abril | 29 | 18 | 47 |
2023 Marzo | 42 | 20 | 62 |
2023 Febrero | 35 | 16 | 51 |
2023 Enero | 36 | 23 | 59 |
2022 Diciembre | 49 | 41 | 90 |
2022 Noviembre | 28 | 20 | 48 |
2022 Octubre | 22 | 19 | 41 |
2022 Septiembre | 25 | 32 | 57 |
2022 Agosto | 26 | 33 | 59 |
2022 Julio | 24 | 34 | 58 |
2022 Junio | 25 | 20 | 45 |
2022 Mayo | 32 | 30 | 62 |
2022 Abril | 47 | 35 | 82 |
2022 Marzo | 62 | 50 | 112 |
2022 Febrero | 43 | 34 | 77 |
2022 Enero | 46 | 41 | 87 |
2021 Diciembre | 27 | 30 | 57 |
2021 Noviembre | 32 | 43 | 75 |
2021 Octubre | 36 | 42 | 78 |
2021 Septiembre | 35 | 29 | 64 |
2021 Agosto | 33 | 30 | 63 |
2021 Julio | 35 | 27 | 62 |
2021 Junio | 21 | 21 | 42 |
2021 Mayo | 40 | 53 | 93 |
2021 Abril | 103 | 56 | 159 |
2021 Marzo | 62 | 37 | 99 |
2021 Febrero | 65 | 33 | 98 |
2021 Enero | 26 | 19 | 45 |
2020 Diciembre | 31 | 17 | 48 |
2020 Noviembre | 28 | 17 | 45 |
2020 Octubre | 19 | 16 | 35 |
2020 Septiembre | 28 | 22 | 50 |
2020 Agosto | 26 | 12 | 38 |
2020 Julio | 18 | 18 | 36 |
2020 Junio | 33 | 30 | 63 |
2020 Mayo | 19 | 18 | 37 |
2020 Abril | 14 | 13 | 27 |
2020 Marzo | 17 | 15 | 32 |
2020 Febrero | 1 | 0 | 1 |