Images in Dermatology
Rare Tongue Compromising of Mucocutaneous Leishmaniasis by Leishmania Subgenus Viannia
Raro compromiso lingual de leishmaniasis mucocutánea por Leishmania perteneciente al subgénero Viannia
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"apellidos" => "Roselino" "email" => array:1 [ 0 => "amfrosel@fmrp.usp.br" ] "referencia" => array:2 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] 1 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">*</span>" "identificador" => "cor0005" ] ] ] ] "afiliaciones" => array:2 [ 0 => array:3 [ "entidad" => "Unidad de Dermatología, Departamento de Clínica Médica, Facultad de Medicina de Ribeirão Preto, Universidad de São Paulo, São Paulo, Brasil" "etiqueta" => "a" "identificador" => "aff0005" ] 1 => array:3 [ "entidad" => "Unidad de Dermatología, Departamento de Clínica Médica, Universidad de Brasilia, Distrito Federal, Brasil" "etiqueta" => "b" "identificador" => "aff0010" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "⁎" "correspondencia" => "Corresponding author." ] ] ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Raro compromiso lingual de leishmaniasis mucocutánea por <span class="elsevierStyleItalic">Leishmania</span> perteneciente al subgénero <span class="elsevierStyleItalic">Viannia</span>" ] ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:6 [ "identificador" => "fig0005" "etiqueta" => "Figure 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 756 "Ancho" => 1138 "Tamanyo" => 175538 ] ] ] ] "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">A 61-years-old male, native from <span class="elsevierStyleItalic">Minas Gerais</span> State, Southeastern Brazil (deny travels overseas), retired electrician, with dyslipidemia and hypertension was admitted for evaluation of an ulcer on his tongue, which appeared five months after an ulcer on the dorsum of his right foot. Histopathology of the previous foot ulcer described a chronic inflammatory process with granuloma formation. Spiramycin and fluconazole were prescribed without improvement, therefore it was surgically removed.</p><p id="par0010" class="elsevierStylePara elsevierViewall">Clinical examination showed a 3.5 by 2.5<span class="elsevierStyleHsp" style=""></span>cm well-circumscribed ulcerated lesion on the left side of his tongue (<a class="elsevierStyleCrossRef" href="#fig0005">Figure 1</a> A), submandibular and lymphadenopathies on the left side. Histopathology on incisional tongue biopsy showed pseudoepiteliomatous hyperplasia and dermal lymphohistiocytic infiltrate, rich in plasma cells, with no microorganisms. Routine laboratory investigations and ELISA test for leishmaniasis were negative or normal, including negative results for human immunodeficiency virus. Leishmanin skin test was positive and polymerase chain reaction performed on tongue biopsies revealed <span class="elsevierStyleItalic">Leishmania</span> subgenus <span class="elsevierStyleItalic">Viannia</span> (corresponding to <span class="elsevierStyleItalic">Leishmania Viannia braziliensis</span> due to local Leishmania species epidemiology). He was treated with liposomal amphotericin B - 3000<span class="elsevierStyleHsp" style=""></span>mg cumulative dose (35<span class="elsevierStyleHsp" style=""></span>mg/kg administered for 28-days), and presented complete tongue healing two months after treatment (<a class="elsevierStyleCrossRef" href="#fig0005">Figure 1</a>B), without any adverse effect. Physicians working in American Tegumentary Leishmaniasis endemic areas should be aware of this rare mucous form presented here whose clinical aspect may be differentiated mainly from epidermoid carcinoma.</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia></span>" "pdfFichero" => "main.pdf" "tienePdf" => true "NotaPie" => array:1 [ 0 => array:2 [ "etiqueta" => "☆" "nota" => "<p class="elsevierStyleNotepara" id="npar0005">Please cite this article as: Bueno-Filho R, Vernal S, Gomes CM, Roselino AM. Raro compromiso lingual de leishmaniasis mucocutánea por <span class="elsevierStyleItalic">Leishmania</span> perteneciente al subgénero <span class="elsevierStyleItalic">Viannia</span>. Actas Dermosifiliogr. 2018;109:651.</p>" ] ] "multimedia" => array:1 [ 0 => array:6 [ "identificador" => "fig0005" "etiqueta" => "Figure 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 756 "Ancho" => 1138 "Tamanyo" => 175538 ] ] ] ] ] "idiomaDefecto" => "en" "url" => "/15782190/0000010900000007/v1_201809020417/S1578219018301896/v1_201809020417/en/main.assets" "Apartado" => array:4 [ "identificador" => "41141" "tipo" => "SECCION" "en" => array:2 [ "titulo" => "Images in Dermatology" "idiomaDefecto" => true ] "idiomaDefecto" => "en" ] "PDF" => "https://static.elsevier.es/multimedia/15782190/0000010900000007/v1_201809020417/S1578219018301896/v1_201809020417/en/main.pdf?idApp=UINPBA000044&text.app=https://actasdermo.org/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219018301896?idApp=UINPBA000044" ]
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