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García del Pozo, C. Martín de Hijas, L. Iñíguez" "autores" => array:3 [ 0 => array:2 [ "nombre" => "M.C." "apellidos" => "García del Pozo" ] 1 => array:2 [ "nombre" => "C." "apellidos" => "Martín de Hijas" ] 2 => array:2 [ "nombre" => "L." 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Velasco-Tamariz, J.L. Rodríguez-Peralto, A. Guerra-Tapia" "autores" => array:3 [ 0 => array:2 [ "nombre" => "V." "apellidos" => "Velasco-Tamariz" ] 1 => array:2 [ "nombre" => "J.L." "apellidos" => "Rodríguez-Peralto" ] 2 => array:2 [ "nombre" => "A." "apellidos" => "Guerra-Tapia" ] ] ] ] ] "idiomaDefecto" => "en" "Traduccion" => array:1 [ "es" => array:9 [ "pii" => "S0001731017304969" "doi" => "10.1016/j.ad.2017.02.036" "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:1 [ "total" => 0 ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0001731017304969?idApp=UINPBA000044" ] ] "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S157821901830163X?idApp=UINPBA000044" "url" => "/15782190/0000010900000006/v1_201808010420/S157821901830163X/v1_201808010420/en/main.assets" ] "itemAnterior" => array:19 [ "pii" => "S1578219018301720" "issn" => "15782190" "doi" => "10.1016/j.adengl.2018.05.014" "estado" => "S300" "fechaPublicacion" => "2018-07-01" "aid" => "1750" "copyright" => "Elsevier España, S.L.U. and AEDV" "documento" => "simple-article" "crossmark" => 1 "subdocumento" => "crp" "cita" => "Actas Dermosifiliogr. 2018;109:e42-6" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 3 "formatos" => array:2 [ "HTML" => 1 "PDF" => 2 ] ] "en" => array:13 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">e- Case Report</span>" "titulo" => "Juvenile Dermatomyositis: Key Roles of Muscle Magnetic Resonance Imaging and Early Aggressive Treatment" "tienePdf" => "en" "tieneTextoCompleto" => "en" "tieneResumen" => array:2 [ 0 => "en" 1 => "es" ] "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "e42" "paginaFinal" => "e46" ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "La resonancia magnética muscular y el tratamiento agresivo precoz, claves en la dermatomiositis juvenil" ] ] "contieneResumen" => array:2 [ "en" => true "es" => true ] "contieneTextoCompleto" => array:1 [ "en" => true ] "contienePdf" => array:1 [ "en" => true ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:7 [ "identificador" => "fig0005" "etiqueta" => "Figure 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 1849 "Ancho" => 2500 "Tamanyo" => 213748 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">Magnetic resonance imaging (MRI) findings. A, Patient #1. Whole-body muscle MRI. Increased intensity in STIR (short tau inversion recovery) sequence of buttock region and vastus lateralis, consistent with muscle edema, a sign of muscle inflammation. Integration of this finding confirmed the diagnosis of juvenile dermatomyositis. B, Patient #4. MRI of shoulder muscle. Increased signal from right deltoids and fascia in association with a small quantity of liquid in the subacromial bursa. C, patient #5. Whole-body muscle MRI after initiation of treatment. Note the hypointense calcinosis cutis plaque in the right low lumbar region (*).</p>" ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "O. Corral-Magaña, A.F. Bauzá-Alonso, M.M. Escudero-Góngora, L. Lacruz, A. Martín-Santiago" "autores" => array:5 [ 0 => array:2 [ "nombre" => "O." "apellidos" => "Corral-Magaña" ] 1 => array:2 [ "nombre" => "A.F." "apellidos" => "Bauzá-Alonso" ] 2 => array:2 [ "nombre" => "M.M." 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"apellidos" => "Martín-Santiago" ] ] ] ] ] "idiomaDefecto" => "en" "Traduccion" => array:1 [ "es" => array:9 [ "pii" => "S0001731017303782" "doi" => "10.1016/j.ad.2017.07.003" "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:1 [ "total" => 0 ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0001731017303782?idApp=UINPBA000044" ] ] "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219018301720?idApp=UINPBA000044" "url" => "/15782190/0000010900000006/v1_201808010420/S1578219018301720/v1_201808010420/en/main.assets" ] "en" => array:15 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Case for Diagnosis</span>" "titulo" => "Erythematous Pedunculated Papule on the Knee" "tieneTextoCompleto" => true "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "543" "paginaFinal" => "544" ] ] "autores" => array:1 [ 0 => array:4 [ "autoresLista" => "M.C. García del Pozo, C. Martín de Hijas, L. Íñiguez de Onzoño" "autores" => array:3 [ 0 => array:4 [ "nombre" => "M.C." "apellidos" => "García del Pozo" "email" => array:1 [ 0 => "sakuragarciadelpozo@hotmail.com" ] "referencia" => array:2 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] 1 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">*</span>" "identificador" => "cor0005" ] ] ] 1 => array:3 [ "nombre" => "C." "apellidos" => "Martín de Hijas" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] ] ] 2 => array:3 [ "nombre" => "L." "apellidos" => "Íñiguez de Onzoño" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff0010" ] ] ] ] "afiliaciones" => array:2 [ 0 => array:3 [ "entidad" => "Servicio de Dermatología Médico-Quirúrgica y Venereología, Complejo Hospitalario Universitario de Albacete, Albacete, Spain" "etiqueta" => "a" "identificador" => "aff0005" ] 1 => array:3 [ "entidad" => "Servicio de Anatomía Patológica, Complejo Hospitalario Universitario de Albacete, Albacete, Spain" "etiqueta" => "b" "identificador" => "aff0010" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "⁎" "correspondencia" => "Corresponding author." ] ] ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Pápula eritematosa pediculada en la rodilla" ] ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:7 [ "identificador" => "fig0015" "etiqueta" => "Figure 3" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr3.jpeg" "Alto" => 571 "Ancho" => 750 "Tamanyo" => 183266 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Hematoxylin-eosin, original magnification ×10.</p>" ] ] ] "textoCompleto" => "<span class="elsevierStyleSections"><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0005">Medical History</span><p id="par0005" class="elsevierStylePara elsevierViewall">An 81-year-old man with a past history of type 2 diabetes mellitus, hypertension, hypercholesterolemia, and chronic bronchitis presented with an asymptomatic lesion on the left popliteal fossa that had grown steadily in size since appearing 1 year earlier.</p></span><span id="sec0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0010">Physical Examination</span><p id="par0010" class="elsevierStylePara elsevierViewall">Physical examination revealed a 6-mm-long erythematous pedunculated papule on the left popliteal fossa that was firm in consistency, showed no erosion or ulceration, and was not adherent to deeper tissues (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>). The patient had no palpable locoregional lymph nodes.</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia></span><span id="sec0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0015">Histopathology</span><p id="par0015" class="elsevierStylePara elsevierViewall">Complete excision of the lesion was performed. Pathologic examination revealed a nonencapsulated polypoid neoformation (<a class="elsevierStyleCrossRef" href="#fig0010">Fig. 2</a>) composed of dermal tumor nodules separated by fibrous tracts. The nodules consisted of 2 types of cells: round cells with clear cytoplasm showing a positive periodic acid-Schiff reaction (<a class="elsevierStyleCrossRef" href="#fig0015">Fig. 3</a>) and polyhedral cells with round nuclei and slightly basophilic cytoplasm. No mitotic figures or angiolymphatic or perineural invasion were observed. Also present were cysts containing homogeneous eosinophilic material, surrounded by a layer of cuboidal epithelial cells, with no evidence of decapitation secretion.<span class="elsevierStyleVsp" style="height:0.5px"></span></p><elsevierMultimedia ident="fig0010"></elsevierMultimedia><elsevierMultimedia ident="fig0015"></elsevierMultimedia><p id="par0020" class="elsevierStylePara elsevierViewall"><span class="elsevierStyleBold">What Is Your Diagnosis?</span></p></span><span id="sec0020" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0020">Diagnosis</span><p id="par0025" class="elsevierStylePara elsevierViewall">Nodular hidradenoma.</p></span><span id="sec0025" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0025">Clinical Course</span><p id="par0030" class="elsevierStylePara elsevierViewall">Follow-up at 1 year showed no recurrence of the lesion.</p></span><span id="sec0030" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0030">Comment</span><p id="par0035" class="elsevierStylePara elsevierViewall">Nodular hidradenoma (also known as apocrine hidradenoma, clear cell hidradenoma, solid-cystic hidradenoma, eccrine acrospiroma, and clear cell acrospiroma) is a benign tumor. The apocrine or eccrine differentiation of this entity has been the subject of debate. Some authors have reported decapitation secretion, which suggests an apocrine origin; others have noted the absence of apocrine secretion and the existence of ultrastructural features of immature eccrine glands.<a class="elsevierStyleCrossRef" href="#bib0035"><span class="elsevierStyleSup">1</span></a> This entity is more common in women and tends to appear between the fourth and sixth decades of life, but cases in children have also been reported.<a class="elsevierStyleCrossRefs" href="#bib0040"><span class="elsevierStyleSup">2,3</span></a> The lesion tends to present as a single, slow-growing, skin-colored or erythematous-brownish nodule measuring less than 2-3<span class="elsevierStyleHsp" style=""></span>cm in diameter, either firm in consistency or fluctuant if the cystic component is predominant. The tumors are generally asymptomatic but erosion or ulceration can be present and, in cystic lesions, serous discharge can be present.<a class="elsevierStyleCrossRef" href="#bib0040"><span class="elsevierStyleSup">2</span></a> Pedunculated lesions—like that of our patient—have been reported but are very rare.<a class="elsevierStyleCrossRef" href="#bib0050"><span class="elsevierStyleSup">4</span></a> The lesion can appear on any part of the body, although the head and neck, trunk, and upper limbs are the most common sites. Dermoscopy shows homogeneous reddish, bluish, bluish-red, or brown areas comprising all or part of the lesion, whitish vascular structures such as arborizing telangiectasias, and polymorphous atypical vessels, making these lesions difficult to distinguish from basal cell carcinomas and melanomas.<a class="elsevierStyleCrossRef" href="#bib0055"><span class="elsevierStyleSup">5</span></a> Immunohistochemical analysis shows positivity for anticytokeratin CAM 5.2 in most tumors. Carcinoembryonic antigen, epithelial membrane antigen, S-100 protein, smooth muscle actin, and vimentin are also expressed in some cases. Staining with antibodies targeting various cytokeratin subtypes is variable in different parts of the tumor.<a class="elsevierStyleCrossRef" href="#bib0040"><span class="elsevierStyleSup">2</span></a> However, immunohistochemical analysis is not usually necessary because this entity can be diagnosed easily with conventional techniques such as hematoxylin-eosin staining. Malignant transformation into hidradenocarcinoma is very rare and should be suspected when histologic examination reveals a pattern of infiltrative growth, necrosis, nuclear pleomorphism, abundant mitotic figures, and angiolymphatic or perineural invasion.<a class="elsevierStyleCrossRef" href="#bib0060"><span class="elsevierStyleSup">6</span></a></p><p id="par0040" class="elsevierStylePara elsevierViewall">Surgical resection is curative; however, the rate of recurrence—due to incomplete resection—is approximately 10%.<a class="elsevierStyleCrossRef" href="#bib0040"><span class="elsevierStyleSup">2</span></a></p><p id="par0045" class="elsevierStylePara elsevierViewall">In this article, we describe a case of nodular hidradenoma with a rare pedunculated presentation. This unusual variety of the lesion must be differentiated from entities of similar morphology, such as fibroepithelioma of Pinkus, fibrolipoma, and angioma. The histologic differential diagnosis includes other clear cell malignancies such as metastatic cancer (usually of renal cell carcinoma) and primary cutaneous tumors with follicular, sebaceous, and sweat gland differentiation.<a class="elsevierStyleCrossRef" href="#bib0060"><span class="elsevierStyleSup">6</span></a></p></span><span id="sec0035" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0035">Conflicts of Interest</span><p id="par0050" class="elsevierStylePara elsevierViewall">The authors declare that they have no conflicts of interest.</p></span></span>" "textoCompletoSecciones" => array:1 [ "secciones" => array:8 [ 0 => array:2 [ "identificador" => "sec0005" "titulo" => "Medical History" ] 1 => array:2 [ "identificador" => "sec0010" "titulo" => "Physical Examination" ] 2 => array:2 [ "identificador" => "sec0015" "titulo" => "Histopathology" ] 3 => array:2 [ "identificador" => "sec0020" "titulo" => "Diagnosis" ] 4 => array:2 [ "identificador" => "sec0025" "titulo" => "Clinical Course" ] 5 => array:2 [ "identificador" => "sec0030" "titulo" => "Comment" ] 6 => array:2 [ "identificador" => "sec0035" "titulo" => "Conflicts of Interest" ] 7 => array:1 [ "titulo" => "References" ] ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "NotaPie" => array:1 [ 0 => array:2 [ "etiqueta" => "☆" "nota" => "<p class="elsevierStyleNotepara" id="npar0005">Please cite this article as: García del Pozo MC, Martín de Hijas C, Iñíguez L. Pápula eritematosa pediculada en la rodilla. Actas Dermosifiliogr. 2018;109:543–544.</p>" ] ] "multimedia" => array:3 [ 0 => array:6 [ "identificador" => "fig0005" "etiqueta" => "Figure 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 645 "Ancho" => 750 "Tamanyo" => 42048 ] ] ] 1 => array:7 [ "identificador" => "fig0010" "etiqueta" => "Figure 2" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr2.jpeg" "Alto" => 879 "Ancho" => 750 "Tamanyo" => 201944 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Panoramic view (hematoxylin-eosin).</p>" ] ] 2 => array:7 [ "identificador" => "fig0015" "etiqueta" => "Figure 3" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr3.jpeg" "Alto" => 571 "Ancho" => 750 "Tamanyo" => 183266 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Hematoxylin-eosin, original magnification ×10.</p>" ] ] ] "bibliografia" => array:2 [ "titulo" => "References" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0015" "bibliografiaReferencia" => array:6 [ 0 => array:3 [ "identificador" => "bib0035" "etiqueta" => "1" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "What is your diagnosis? Clear cell hidradenoma" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "A. Egesi" 1 => "A. Ingraffea" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Cutis" "fecha" => "2014" "volumen" => "94" "paginaInicial" => "271" "paginaFinal" => "272" ] ] ] ] ] ] 1 => array:3 [ "identificador" => "bib0040" "etiqueta" => "2" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "A Weeping Tumor in a Young Girl: An Unusual Presentation of Nodular Hidradenoma" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "A. Das" 1 => "T. Gayen" 2 => "I. Podder" 3 => "K. Shome" 4 => "D. 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año/Mes | Html | Total | |
---|---|---|---|
2024 Noviembre | 7 | 12 | 19 |
2024 Octubre | 91 | 56 | 147 |
2024 Septiembre | 111 | 45 | 156 |
2024 Agosto | 128 | 71 | 199 |
2024 Julio | 82 | 43 | 125 |
2024 Junio | 114 | 35 | 149 |
2024 Mayo | 92 | 45 | 137 |
2024 Abril | 98 | 23 | 121 |
2024 Marzo | 91 | 33 | 124 |
2024 Febrero | 80 | 38 | 118 |
2024 Enero | 77 | 36 | 113 |
2023 Diciembre | 80 | 19 | 99 |
2023 Noviembre | 119 | 29 | 148 |
2023 Octubre | 95 | 37 | 132 |
2023 Septiembre | 95 | 48 | 143 |
2023 Agosto | 65 | 16 | 81 |
2023 Julio | 126 | 46 | 172 |
2023 Junio | 104 | 29 | 133 |
2023 Mayo | 84 | 30 | 114 |
2023 Abril | 82 | 30 | 112 |
2023 Marzo | 105 | 36 | 141 |
2023 Febrero | 85 | 31 | 116 |
2023 Enero | 54 | 50 | 104 |
2022 Diciembre | 41 | 47 | 88 |
2022 Noviembre | 35 | 27 | 62 |
2022 Octubre | 37 | 30 | 67 |
2022 Septiembre | 29 | 33 | 62 |
2022 Agosto | 29 | 43 | 72 |
2022 Julio | 27 | 34 | 61 |
2022 Junio | 30 | 23 | 53 |
2022 Mayo | 72 | 41 | 113 |
2022 Abril | 50 | 43 | 93 |
2022 Marzo | 64 | 43 | 107 |
2022 Febrero | 59 | 27 | 86 |
2022 Enero | 62 | 52 | 114 |
2021 Diciembre | 40 | 43 | 83 |
2021 Noviembre | 59 | 57 | 116 |
2021 Octubre | 60 | 67 | 127 |
2021 Septiembre | 53 | 43 | 96 |
2021 Agosto | 77 | 49 | 126 |
2021 Julio | 52 | 41 | 93 |
2021 Junio | 51 | 43 | 94 |
2021 Mayo | 43 | 61 | 104 |
2021 Abril | 112 | 92 | 204 |
2021 Marzo | 66 | 41 | 107 |
2021 Febrero | 68 | 37 | 105 |
2021 Enero | 48 | 52 | 100 |
2020 Diciembre | 47 | 51 | 98 |
2020 Noviembre | 35 | 42 | 77 |
2020 Octubre | 28 | 20 | 48 |
2020 Septiembre | 53 | 29 | 82 |
2020 Agosto | 22 | 31 | 53 |
2020 Julio | 28 | 21 | 49 |
2020 Junio | 38 | 47 | 85 |
2020 Mayo | 17 | 22 | 39 |
2020 Abril | 16 | 16 | 32 |
2020 Marzo | 27 | 10 | 37 |
2019 Mayo | 2 | 1 | 3 |