Case and Research Letter
A Typical Case of Lipoblastoma on the Lower Limb of an Infant
Lipoblastoma en la extremidad inferior de un lactante. Un caso representativo
L. Giraldo Mordecay
, M.P. Novoa Candia, C.E. Torres Fuentes, A.M. Sastre Zuluaga
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Fundación Universitaria de Ciencias de la Salud, Hospital San José, Bogotá, Colombia
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Giraldo Mordecay, M.P. Novoa Candia, C.E. Torres Fuentes, A.M. Sastre Zuluaga" "autores" => array:4 [ 0 => array:4 [ "nombre" => "L. Giraldo" "apellidos" => "Mordecay" "email" => array:1 [ 0 => "luciagir@gmail.com" ] "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">*</span>" "identificador" => "cor0005" ] ] ] 1 => array:2 [ "nombre" => "M.P. Novoa" "apellidos" => "Candia" ] 2 => array:2 [ "nombre" => "C.E. Torres" "apellidos" => "Fuentes" ] 3 => array:2 [ "nombre" => "A.M. Sastre" "apellidos" => "Zuluaga" ] ] "afiliaciones" => array:1 [ 0 => array:2 [ "entidad" => "Fundación Universitaria de Ciencias de la Salud, Hospital San José, Bogotá, Colombia" "identificador" => "aff0005" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "⁎" "correspondencia" => "Corresponding author." ] ] ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Lipoblastoma en la extremidad inferior de un lactante. Un caso representativo" ] ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:7 [ "identificador" => "fig0015" "etiqueta" => "Figure 3" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr3.jpeg" "Alto" => 919 "Ancho" => 1667 "Tamanyo" => 320556 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">A and B, Mesenchymal lesion composed of immature fat cells (hematoxylin-eosin, original magnification ×10) and spindle cells (hematoxylin-eosin, original magnification ×40).</p>" ] ] ] "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">Lipoblastoma is a childhood tumor that usually appears in the first 3 years of life, although it may sometimes be present at birth. It occurs as a well-circumscribed lesion in the superficial subcutaneous tissue.<a class="elsevierStyleCrossRef" href="#bib0080"><span class="elsevierStyleSup">1</span></a></p><p id="par0010" class="elsevierStylePara elsevierViewall">Lipoblastoma accounts for between 5% and 30% of all soft-tissue tumors in children. The most common sites of occurrence are the upper and lower extremities, although the head, neck, and trunk may also be affected. On fewer occasions, there have been reports of retroperitoneal, mesenterial, mediastinal, and parotid lipoblastomas.<a class="elsevierStyleCrossRefs" href="#bib0080"><span class="elsevierStyleSup">1,2</span></a> The classic presentation is that of a smooth, painless, slow-growing mass that can sometimes displace neighboring structures or cause deformity of the anatomic region in which it is located.<a class="elsevierStyleCrossRef" href="#bib0090"><span class="elsevierStyleSup">3</span></a></p><p id="par0015" class="elsevierStylePara elsevierViewall">We report the case of a 5-month-old boy with a soft, recalcitrant mass on his middle left toe (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>). The mass had appeared in the first month of life and had exhibited fast, progressive growth. Soft-tissue ultrasound showed a solid, circumscribed lesion with a vascular appearance. Contrast magnetic resonance imaging (MRI) showed a well-defined solid mass with a vascular appearance consistent with a hemangioma or a low-flow vascular malformation.</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><p id="par0020" class="elsevierStylePara elsevierViewall">Because of its fast growth and deforming nature, the mass was removed by complete skin-sparing surgical excision with Z-plasty repair (<a class="elsevierStyleCrossRef" href="#fig0010">Fig. 2</a>). The pathology report described a well-defined, expansive mesenchymal lesion with multiple lobules of fat cells, some of which were immature, accompanied by an abundant myxoid matrix and a proliferation of nonatypical spindle cells with a soft appearance (<a class="elsevierStyleCrossRef" href="#fig0015">Figs. 3</a>A and B)</p><elsevierMultimedia ident="fig0010"></elsevierMultimedia><elsevierMultimedia ident="fig0015"></elsevierMultimedia><p id="par0025" class="elsevierStylePara elsevierViewall">The patient progressed adequately and showed no signs of recurrence in the 6 months after the procedure.</p><p id="par0030" class="elsevierStylePara elsevierViewall">Lipoblastomas are rare, benign mesenchymal tumors. They can be superficial (slow-growing well-circumscribed lesions) or diffuse (multicentric lesions arising in skeletal muscle or in the retroperitoneum or mesentery).<a class="elsevierStyleCrossRef" href="#bib0090"><span class="elsevierStyleSup">3</span></a></p><p id="par0035" class="elsevierStylePara elsevierViewall">Diagnosis should be based on the integration of clinical manifestations and diagnostic images, such as ultrasound, computed tomography (CT), and MRI. A definitive diagnosis, however, should be based on histopathological findings, and malignancy must be ruled out.</p><p id="par0040" class="elsevierStylePara elsevierViewall">Histologically, lipoblastoma presents as a cellular tumor composed of immature fat cells (lipoblasts) with relatively well-defined septae and a fine vascular network. There is no pleomorphism or atypia.<a class="elsevierStyleCrossRef" href="#bib0090"><span class="elsevierStyleSup">3</span></a> The most common form is myxoid lipoblastoma, which has abundant interstitial mucin in over 50% of the specimen. Genetic and pathological studies may be of use when microscopy does not provide a definitive diagnosis.<a class="elsevierStyleCrossRef" href="#bib0090"><span class="elsevierStyleSup">3</span></a> Cytogenetic analyses and certain molecular tests are proving to be of diagnostic value. Evidence of genetic anomalies in lipoblastoma includes chromosomal rearrangements involving the 8q11.13 region and rearrangement of the pleomorphic adenoma gene 1 (<span class="elsevierStyleItalic">PLAG1</span>) in chromosome 8.<a class="elsevierStyleCrossRefs" href="#bib0090"><span class="elsevierStyleSup">3,4</span></a> These anomalies have not been observed in malignant tumors, such as liposarcoma. The differential diagnosis should include malignant soft-tissue tumors, such as liposarcoma, myxoid liposarcoma, rhabdomyosarcoma, and desmoid tumor, in addition to other benign tumors, such as lipoma, spindle-cell lipoma, and hibernoma. While clinically similar, some of these tumors present in adults. In addition, fat cells in both hibernoma and spindle-cell lipoma stain positively for protein S100.<a class="elsevierStyleCrossRefs" href="#bib0100"><span class="elsevierStyleSup">5,6</span></a> Lipoblastomas can also simulate vascular tumors, such as hemangiomas and angiolipomas.<a class="elsevierStyleCrossRef" href="#bib0110"><span class="elsevierStyleSup">7</span></a> MDM2 and CDK4 are overexpressed in liposarcoma and positive immunohistochemical staining can therefore confirm malignancy and rule out other benign entities.<a class="elsevierStyleCrossRef" href="#bib0115"><span class="elsevierStyleSup">8</span></a></p><p id="par0045" class="elsevierStylePara elsevierViewall">There have been few reports of childhood lipoblastoma involving the lower extremities and some of these are summarized in <a class="elsevierStyleCrossRef" href="#tbl0005">Table 1</a>.<a class="elsevierStyleCrossRefs" href="#bib0120"><span class="elsevierStyleSup">9–15</span></a></p><elsevierMultimedia ident="tbl0005"></elsevierMultimedia><p id="par0050" class="elsevierStylePara elsevierViewall">The treatment of choice is surgical excision. Recurrence following excision occurs in 9% to 33% of cases and tends to occur within 2 years of treatment.<a class="elsevierStyleCrossRefs" href="#bib0090"><span class="elsevierStyleSup">3–7</span></a></p><p id="par0055" class="elsevierStylePara elsevierViewall">Lipoblastoma is a rare soft-tissue mesenchymal tumor that occurs almost exclusively in childhood. It is important to contemplate this entity in the differential diagnosis of fast-growing lesions that can simulate vascular lesions in imaging studies. This occurred in our case, where the histopathological examination had a key diagnostic role.</p><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0005">Conflicts Of Interest</span><p id="par0060" class="elsevierStylePara elsevierViewall">The authors declare that they have no conflicts of interest.</p></span></span>" "textoCompletoSecciones" => array:1 [ "secciones" => array:2 [ 0 => array:2 [ "identificador" => "sec0005" "titulo" => "Conflicts Of Interest" ] 1 => array:1 [ "titulo" => "References" ] ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "NotaPie" => array:1 [ 0 => array:2 [ "etiqueta" => "☆" "nota" => "<p class="elsevierStyleNotepara" id="npar0005">Please cite this article as: Mordecay LG, Candia MPN, Fuentes CET, Zuluaga AMS. Lipoblastoma en la extremidad inferior de un lactante. Un caso representativo. Actas Dermosifiliogr. 2018;109:450–452.</p>" ] ] "multimedia" => array:4 [ 0 => array:7 [ "identificador" => "fig0005" "etiqueta" => "Figure 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 630 "Ancho" => 750 "Tamanyo" => 111744 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Soft erythematous mass on the right middle toe.</p>" ] ] 1 => array:7 [ "identificador" => "fig0010" "etiqueta" => "Figure 2" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr2.jpeg" "Alto" => 788 "Ancho" => 750 "Tamanyo" => 61038 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Complete surgical excision.</p>" ] ] 2 => array:7 [ "identificador" => "fig0015" "etiqueta" => "Figure 3" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr3.jpeg" "Alto" => 919 "Ancho" => 1667 "Tamanyo" => 320556 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">A and B, Mesenchymal lesion composed of immature fat cells (hematoxylin-eosin, original magnification ×10) and spindle cells (hematoxylin-eosin, original magnification ×40).</p>" ] ] 3 => array:8 [ "identificador" => "tbl0005" "etiqueta" => "Table 1" "tipo" => "MULTIMEDIATABLA" "mostrarFloat" => true "mostrarDisplay" => false "detalles" => array:1 [ 0 => array:3 [ "identificador" => "at1" "detalle" => "Table " "rol" => "short" ] ] "tabla" => array:2 [ "leyenda" => "<p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">Abbreviations: F, female; M, male.</p>" "tablatextoimagen" => array:1 [ 0 => array:2 [ "tabla" => array:1 [ 0 => """ <table border="0" frame="\n \t\t\t\t\tvoid\n \t\t\t\t" class=""><thead title="thead"><tr title="table-row"><th class="td" title="table-head " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">Author (Year) \t\t\t\t\t\t\n \t\t\t\t</th><th class="td" title="table-head " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">No. of Cases \t\t\t\t\t\t\n \t\t\t\t</th><th class="td" title="table-head " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">Age, y \t\t\t\t\t\t\n \t\t\t\t</th><th class="td" title="table-head " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">Sex \t\t\t\t\t\t\n \t\t\t\t</th><th class="td" title="table-head " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">Location \t\t\t\t\t\t\n \t\t\t\t</th><th class="td" title="table-head " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">Time Since Onset \t\t\t\t\t\t\n \t\t\t\t</th><th class="td" title="table-head " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">Management \t\t\t\t\t\t\n \t\t\t\t</th><th class="td" title="table-head " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">Outcome After Surgery \t\t\t\t\t\t\n \t\t\t\t</th></tr></thead><tbody title="tbody"><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Pirela-Cruz NA (1992) \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">1 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">7 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">M \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">Right foot \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">4 y \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">Surgical resection \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">Good, no recurrence \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Gilbert TJ (1996) \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">1 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">14 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">M \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">Left foot \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">6 mo \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">Surgical resection \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">Good, no recurrence \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Miller G (1998) \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">7 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">1-9.6 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">M/F \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">Feet, thorax, axillae, buttocks, abdominal wall \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">1-3 y \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">Surgical resection \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">Good, no recurrence \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Young RJ (2000) \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">1 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">5 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">F \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">Heel \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">NA \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">Surgical resection \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">Good, no recurrence \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Puri A (2005) \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">1 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">6 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">F \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">Left foot \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">5 y \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">Surgical resection \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">Good, no recurrence \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Chien AL (2006) \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">2 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">1, 5 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">F \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">Right heel, right groin \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">4 mo, 1.5 y \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">Surgical resection \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">Good, no recurrence \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Syed A (2007) \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">1 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">2.5 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">M \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">Left foot \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">1.5 y \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">Surgical resection \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">Good, no recurrence \t\t\t\t\t\t\n \t\t\t\t</td></tr></tbody></table> """ ] "imagenFichero" => array:1 [ 0 => "xTab1761148.png" ] ] ] ] "descripcion" => array:1 [ "en" => "<p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">Summary of Lipoblastoma Cases Reported in the Literature to Date.</p>" ] ] ] "bibliografia" => array:2 [ "titulo" => "References" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0015" "bibliografiaReferencia" => array:15 [ 0 => array:3 [ "identificador" => "bib0080" "etiqueta" => "1" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "An isolated digital lipoblastoma" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "P. 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| año/Mes | Html | Total | |
|---|---|---|---|
| 2024 Noviembre | 12 | 2 | 14 |
| 2024 Octubre | 81 | 55 | 136 |
| 2024 Septiembre | 91 | 39 | 130 |
| 2024 Agosto | 93 | 76 | 169 |
| 2024 Julio | 95 | 46 | 141 |
| 2024 Junio | 105 | 36 | 141 |
| 2024 Mayo | 76 | 31 | 107 |
| 2024 Abril | 102 | 36 | 138 |
| 2024 Marzo | 109 | 30 | 139 |
| 2024 Febrero | 104 | 32 | 136 |
| 2024 Enero | 77 | 36 | 113 |
| 2023 Diciembre | 103 | 26 | 129 |
| 2023 Noviembre | 102 | 29 | 131 |
| 2023 Octubre | 105 | 30 | 135 |
| 2023 Septiembre | 87 | 37 | 124 |
| 2023 Agosto | 68 | 20 | 88 |
| 2023 Julio | 102 | 45 | 147 |
| 2023 Junio | 89 | 23 | 112 |
| 2023 Mayo | 93 | 29 | 122 |
| 2023 Abril | 109 | 29 | 138 |
| 2023 Marzo | 109 | 24 | 133 |
| 2023 Febrero | 82 | 26 | 108 |
| 2023 Enero | 70 | 27 | 97 |
| 2022 Diciembre | 66 | 41 | 107 |
| 2022 Noviembre | 48 | 25 | 73 |
| 2022 Octubre | 33 | 22 | 55 |
| 2022 Septiembre | 33 | 40 | 73 |
| 2022 Agosto | 37 | 34 | 71 |
| 2022 Julio | 22 | 29 | 51 |
| 2022 Junio | 29 | 27 | 56 |
| 2022 Mayo | 53 | 31 | 84 |
| 2022 Abril | 60 | 43 | 103 |
| 2022 Marzo | 66 | 49 | 115 |
| 2022 Febrero | 76 | 28 | 104 |
| 2022 Enero | 87 | 40 | 127 |
| 2021 Diciembre | 55 | 36 | 91 |
| 2021 Noviembre | 55 | 50 | 105 |
| 2021 Octubre | 50 | 54 | 104 |
| 2021 Septiembre | 46 | 41 | 87 |
| 2021 Agosto | 79 | 33 | 112 |
| 2021 Julio | 86 | 24 | 110 |
| 2021 Junio | 64 | 30 | 94 |
| 2021 Mayo | 46 | 39 | 85 |
| 2021 Abril | 120 | 53 | 173 |
| 2021 Marzo | 62 | 34 | 96 |
| 2021 Febrero | 82 | 23 | 105 |
| 2021 Enero | 43 | 21 | 64 |
| 2020 Diciembre | 29 | 12 | 41 |
| 2020 Noviembre | 36 | 25 | 61 |
| 2020 Octubre | 38 | 9 | 47 |
| 2020 Septiembre | 35 | 12 | 47 |
| 2020 Agosto | 32 | 18 | 50 |
| 2020 Julio | 22 | 13 | 35 |
| 2020 Junio | 18 | 29 | 47 |
| 2020 Mayo | 29 | 17 | 46 |
| 2020 Abril | 22 | 14 | 36 |
| 2020 Marzo | 22 | 20 | 42 |
| 2020 Febrero | 4 | 0 | 4 |
| 2020 Enero | 2 | 0 | 2 |
| 2019 Diciembre | 4 | 0 | 4 |
| 2019 Noviembre | 2 | 0 | 2 |
| 2019 Septiembre | 4 | 0 | 4 |
| 2019 Agosto | 4 | 0 | 4 |
| 2019 Julio | 4 | 0 | 4 |
| 2019 Junio | 4 | 0 | 4 |
| 2019 Mayo | 6 | 1 | 7 |
| 2019 Abril | 4 | 0 | 4 |
| 2019 Febrero | 2 | 0 | 2 |
| 2018 Noviembre | 5 | 0 | 5 |
| 2018 Octubre | 1 | 0 | 1 |
| 2018 Septiembre | 2 | 0 | 2 |
| 2018 Julio | 1 | 0 | 1 |
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