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Resident's Forum
Management of Corticosteroid-Induced Osteoporosis: A Practical Approach for the Dermatologist
Manejo de la osteoporosis inducida por corticoides: enfoque práctico para el dermatólogo
C. Vico-Alonsoa,
Autor para correspondencia
c.vicoalonso@gmail.com

Corresponding author.
, L. Maroñas-Jiméneza, F. Lozano-Morillob
a Servicio de Dermatología, Hospital Universitario 12 de Octubre, Madrid, España
b Servicio de Reumatología, Hospital Universitario 12 de Octubre, Madrid, España
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                      "titulo" => "Oral corticosteroids and fracture risk&#58; Relationship to daily and cumulative doses"
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                            0 => "T&#46;P&#46; Van Staa"
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                            2 => "L&#46; Abenhaim"
                            3 => "B&#46; Zhang"
                            4 => "C&#46; Cooper"
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                        ]
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                    ]
                  ]
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                    0 => array:1 [
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                        "paginaInicial" => "1383"
                        "paginaFinal" => "1389"
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                          0 => array:2 [
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              "etiqueta" => "2"
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                        "tituloSerie" => "N Engl J Med&#46;"
                        "fecha" => "2011"
                        "volumen" => "365"
                        "paginaInicial" => "62"
                        "paginaFinal" => "70"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/21732837"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            2 => array:3 [
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              "etiqueta" => "3"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "The epidemiology of corticosteroid-induced osteoporosis&#58; A meta-analysis"
                      "autores" => array:1 [
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                          "etal" => false
                          "autores" => array:3 [
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                        "volumen" => "13"
                        "paginaInicial" => "777"
                        "paginaFinal" => "787"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12378366"
                            "web" => "Medline"
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                      ]
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                  ]
                ]
              ]
            ]
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              "etiqueta" => "4"
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                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Gu&#237;as de pr&#225;ctica cl&#237;nica en la osteoporosis posmenop&#225;usica&#44; glucocorticoidea y del var&#243;n&#46; Sociedad Espa&#241;ola de Investigaci&#243;n &#211;sea y del Metabolismo Mineral &#40;3&#46;a versi&#243;n actualizada 2014&#41;"
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                        "tituloSerie" => "Rev Clin Esp&#46;"
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