Case and Research Letter
Reticulate Acropigmentation of Kitamura and Nevus of Ito
Acropigmentación reticulada de Kitamura y nevus de Ito
Leído
10620
Vecesse ha leído el artículo
2607
Total PDF
8013
Total HTML
Compartir estadísticas
array:24 [ "pii" => "S1578219017302159" "issn" => "15782190" "doi" => "10.1016/j.adengl.2017.06.018" "estado" => "S300" "fechaPublicacion" => "2017-09-01" "aid" => "1636" "copyright" => "Elsevier España, S.L.U. and AEDV" "copyrightAnyo" => "2017" "documento" => "simple-article" "crossmark" => 1 "subdocumento" => "crp" "cita" => "Actas Dermosifiliogr. 2017;108:675-7" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 659 "formatos" => array:3 [ "EPUB" => 29 "HTML" => 523 "PDF" => 107 ] ] "Traduccion" => array:1 [ "es" => array:19 [ "pii" => "S0001731017301230" "issn" => "00017310" "doi" => "10.1016/j.ad.2016.11.024" "estado" => "S300" "fechaPublicacion" => "2017-09-01" "aid" => "1636" "copyright" => "AEDV" "documento" => "simple-article" "crossmark" => 1 "subdocumento" => "crp" "cita" => "Actas Dermosifiliogr. 2017;108:675-7" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 377 "formatos" => array:3 [ "EPUB" => 5 "HTML" => 288 "PDF" => 84 ] ] "es" => array:11 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">CARTA CIENTÍFICO-CLÍNICA</span>" "titulo" => "Acropigmentación reticulada de Kitamura y nevus de Ito" "tienePdf" => "es" "tieneTextoCompleto" => "es" "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "675" "paginaFinal" => "677" ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Reticulate Acropigmentation of Kitamura and Nevus of Ito" ] ] "contieneTextoCompleto" => array:1 [ "es" => true ] "contienePdf" => array:1 [ "es" => true ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:7 [ "identificador" => "fig0010" "etiqueta" => "Figura 2" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr2.jpeg" "Alto" => 965 "Ancho" => 2133 "Tamanyo" => 230708 ] ] "descripcion" => array:1 [ "es" => "<p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Placa maculosa en el centro de la espalda, de 13,5<span class="elsevierStyleHsp" style=""></span>×<span class="elsevierStyleHsp" style=""></span>10,5<span class="elsevierStyleHsp" style=""></span>cm, no infiltrada y sin nódulos, con bordes irregulares, color azulado con áreas marrones periféricas (a), así como coloración azul-grisácea menos evidente en el hemitórax derecho (b).</p>" ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "M. García-Arpa, M. Franco-Muñoz, M.A. Flores-Terry, C. Ramos-Rodríguez" "autores" => array:4 [ 0 => array:2 [ "nombre" => "M." "apellidos" => "García-Arpa" ] 1 => array:2 [ "nombre" => "M." "apellidos" => "Franco-Muñoz" ] 2 => array:2 [ "nombre" => "M.A." "apellidos" => "Flores-Terry" ] 3 => array:2 [ "nombre" => "C." "apellidos" => "Ramos-Rodríguez" ] ] ] ] ] "idiomaDefecto" => "es" "Traduccion" => array:1 [ "en" => array:9 [ "pii" => "S1578219017302159" "doi" => "10.1016/j.adengl.2017.06.018" "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:1 [ "total" => 0 ] "idiomaDefecto" => "en" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219017302159?idApp=UINPBA000044" ] ] "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0001731017301230?idApp=UINPBA000044" "url" => "/00017310/0000010800000007/v2_201708291352/S0001731017301230/v2_201708291352/es/main.assets" ] ] "itemSiguiente" => array:19 [ "pii" => "S1578219017301932" "issn" => "15782190" "doi" => "10.1016/j.adengl.2017.06.006" "estado" => "S300" "fechaPublicacion" => "2017-09-01" "aid" => "1635" "copyright" => "Elsevier España, S.L.U. and AEDV" "documento" => "simple-article" "crossmark" => 1 "subdocumento" => "crp" "cita" => "Actas Dermosifiliogr. 2017;108:678-80" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 635 "formatos" => array:3 [ "EPUB" => 28 "HTML" => 495 "PDF" => 112 ] ] "en" => array:11 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Case and Research Letter</span>" "titulo" => "Melanomas Arising on Tattoos: A Casual Association with Practical Implications" "tienePdf" => "en" "tieneTextoCompleto" => "en" "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "678" "paginaFinal" => "680" ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Melanomas sobre tatuajes: una asociación casual con implicaciones prácticas" ] ] "contieneTextoCompleto" => array:1 [ "en" => true ] "contienePdf" => array:1 [ "en" => true ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:7 [ "identificador" => "fig0010" "etiqueta" => "Figure 2" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr2.jpeg" "Alto" => 780 "Ancho" => 1500 "Tamanyo" => 315252 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">A, Melanoma on the left arm over a tattoo that is more than 60 years old. B, Histopathology of the melanoma, in which tattoo ink is visible (hematoxylin-eosin, original magnification ×4). The inset shows a more detailed image (original magnification ×40).</p>" ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "M. Armengot-Carbó, N. Barrado-Solís, C. Martínez-Lahuerta, E. Gimeno-Carpio" "autores" => array:4 [ 0 => array:2 [ "nombre" => "M." "apellidos" => "Armengot-Carbó" ] 1 => array:2 [ "nombre" => "N." "apellidos" => "Barrado-Solís" ] 2 => array:2 [ "nombre" => "C." "apellidos" => "Martínez-Lahuerta" ] 3 => array:2 [ "nombre" => "E." "apellidos" => "Gimeno-Carpio" ] ] ] ] ] "idiomaDefecto" => "en" "Traduccion" => array:1 [ "es" => array:9 [ "pii" => "S0001731017301229" "doi" => "10.1016/j.ad.2016.11.023" "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:1 [ "total" => 0 ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0001731017301229?idApp=UINPBA000044" ] ] "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219017301932?idApp=UINPBA000044" "url" => "/15782190/0000010800000007/v2_201708291348/S1578219017301932/v2_201708291348/en/main.assets" ] "itemAnterior" => array:18 [ "pii" => "S1578219017301920" "issn" => "15782190" "doi" => "10.1016/j.adengl.2017.06.005" "estado" => "S300" "fechaPublicacion" => "2017-09-01" "aid" => "1638" "documento" => "simple-article" "crossmark" => 1 "subdocumento" => "crp" "cita" => "Actas Dermosifiliogr. 2017;108:673-5" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 604 "formatos" => array:3 [ "EPUB" => 36 "HTML" => 471 "PDF" => 97 ] ] "en" => array:11 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Case and Research Letter</span>" "titulo" => "Edematous Dermatomyositis with Probable Evans Syndrome" "tienePdf" => "en" "tieneTextoCompleto" => "en" "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "673" "paginaFinal" => "675" ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Dermatomiositis edematosa asociada a probable síndrome de Evans" ] ] "contieneTextoCompleto" => array:1 [ "en" => true ] "contienePdf" => array:1 [ "en" => true ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:7 [ "identificador" => "fig0005" "etiqueta" => "Figure 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 966 "Ancho" => 851 "Tamanyo" => 132496 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Erythematous-violaceous rash affecting the face and neck. The rash is symmetrical and particularly noticeable on the eyelids.</p>" ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "M.Á. Flores-Terry, M. García-Arpa, J. Anino-Fernández, M.D. Mínguez-Sánchez" "autores" => array:4 [ 0 => array:2 [ "nombre" => "M.Á." "apellidos" => "Flores-Terry" ] 1 => array:2 [ "nombre" => "M." "apellidos" => "García-Arpa" ] 2 => array:2 [ "nombre" => "J." "apellidos" => "Anino-Fernández" ] 3 => array:2 [ "nombre" => "M.D." "apellidos" => "Mínguez-Sánchez" ] ] ] ] ] "idiomaDefecto" => "en" "Traduccion" => array:1 [ "es" => array:9 [ "pii" => "S0001731017301254" "doi" => "10.1016/j.ad.2017.01.020" "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:1 [ "total" => 0 ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0001731017301254?idApp=UINPBA000044" ] ] "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219017301920?idApp=UINPBA000044" "url" => "/15782190/0000010800000007/v2_201708291348/S1578219017301920/v2_201708291348/en/main.assets" ] "en" => array:17 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Case and Research Letter</span>" "titulo" => "Reticulate Acropigmentation of Kitamura and Nevus of Ito" "tieneTextoCompleto" => true "saludo" => "<span class="elsevierStyleItalic">To the Editor:</span>" "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "675" "paginaFinal" => "677" ] ] "autores" => array:1 [ 0 => array:4 [ "autoresLista" => "M. García-Arpa, M. Franco-Muñoz, M.A. Flores-Terry, C. Ramos-Rodríguez" "autores" => array:4 [ 0 => array:4 [ "nombre" => "M." "apellidos" => "García-Arpa" "email" => array:1 [ 0 => "mgarciaa73@yahoo.es" ] "referencia" => array:2 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] 1 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">*</span>" "identificador" => "cor0005" ] ] ] 1 => array:3 [ "nombre" => "M." "apellidos" => "Franco-Muñoz" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] ] ] 2 => array:3 [ "nombre" => "M.A." "apellidos" => "Flores-Terry" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] ] ] 3 => array:3 [ "nombre" => "C." "apellidos" => "Ramos-Rodríguez" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff0010" ] ] ] ] "afiliaciones" => array:2 [ 0 => array:3 [ "entidad" => "Servicio de Dermatología, Hospital General Universitario de Ciudad Real, Ciudad Real, Spain" "etiqueta" => "a" "identificador" => "aff0005" ] 1 => array:3 [ "entidad" => "Servicio de Anatomía Patológica, Hospital General Universitario de Ciudad Real, Ciudad Real, Spain" "etiqueta" => "b" "identificador" => "aff0010" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "⁎" "correspondencia" => "Corresponding author." ] ] ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Acropigmentación reticulada de Kitamura y nevus de Ito" ] ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:7 [ "identificador" => "fig0015" "etiqueta" => "Figure 3" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr3.jpeg" "Alto" => 827 "Ancho" => 2133 "Tamanyo" => 453436 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">A, Findings from a biopsy specimen taken from the wrist. Note the lentiginous epidermal hyperplasia with hyperpigmented bulbous projections of the epidermal rete ridges and increased basal melanocytes (hematoxylin-eosin [H-E], original magnification ×10; detail (inset), original magnification ×40). B, Findings from a biopsy specimen taken from the back. Notice the dendritic melanocytes in the reticular and papillary dermis and hyperpigmentation of the basal layer of the epidermis (H-E, original magnification ×20).</p>" ] ] ] "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">Reticulate acropigmentation of Kitamura (RAPK) is an uncommon genodermatosis that is classed as a congenital reticulate pigmentary disorder. It is characterized by acral lentiginous pigmentation and mainly affects Japanese individuals. Nevus of Ito is a congenital dermal melanocytosis that is congenital and affects the deltoid and acromioclavicular region, more commonly in Asian women.</p><p id="par0010" class="elsevierStylePara elsevierViewall">We report the case of a 47-year-old woman (phototype III) with no clinical history of interest who consulted for progressively slow-growing asymptomatic darkening of the skin on the dorsum of the hands and on the face that began during adolescence. She reported that her mother had similar pigmentation on the hands, although other family members did not (2 maternal aunts, 2 siblings, 3 children). She also had a stable congenital lesion on her back and right hemithorax. Examination revealed symmetrical lentiginous pigmentation on the dorsum of the hands, the anterior aspect of the wrists, the eyelids, and the area around the lips, together with palmoplantar pits and interrupted palmar creases (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>). A blue-grayish plaque was observed on her back and right hemithorax and arm (<a class="elsevierStyleCrossRef" href="#fig0010">Fig. 2</a>). Analysis of a biopsy specimen from the hand revealed lentiginous epidermal hyperplasia with hyperpigmented bulbous projections of the epidermal rete ridges; in the case of the dorsum, it revealed dendritic melanocytes in the dermis (<a class="elsevierStyleCrossRef" href="#fig0015">Fig. 3</a>). These findings led us to diagnose the patient's condition as RAPK and nevus of Ito.</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><elsevierMultimedia ident="fig0010"></elsevierMultimedia><elsevierMultimedia ident="fig0015"></elsevierMultimedia><p id="par0015" class="elsevierStylePara elsevierViewall">Reticulate pigmentary disorders comprise a group of congenital and acquired conditions with reticulate or freckle-type hyperpigmentation and occasional hypopigmentation. There is some confusion in the literature with respect to definitions and terminology. Hereditary forms are unusual and have variable inheritance patterns, although they are generally autosomal dominant, with possible associated abnormalities. They include dyskeratosis congenita, Dowling-Degos disease, RAPK, Haber syndrome, reticulate acropigmentation of Dohi, Naegeli-Franceschetti-Jadassohn syndrome, X-linked reticulate pigmentary disorder, and dyschromatosis universalis hereditaria. In the acquired forms, the lesions are usually larger and include confluent and reticulate papillomatosis (Gougerot-Carteaud), prurigo pigmentosa, lichen planus pigmentosus, Riehl melanosis, erythema ab igne, cutis marmorata, livedo reticularis, and postinflammatory pigmentation.<a class="elsevierStyleCrossRef" href="#bib0055"><span class="elsevierStyleSup">1</span></a></p><p id="par0020" class="elsevierStylePara elsevierViewall">RAPK is an uncommon disorder, with approximately 130 reported cases.<a class="elsevierStyleCrossRefs" href="#bib0060"><span class="elsevierStyleSup">2–7</span></a> While more common in Japan, it can be found throughout the world. The inheritance pattern is autosomal dominant, although nonhereditary cases occur sporadically. It first appears during the first or second decade of life, with reticulate or freckle-like hyperpigmented macules that measure 1 to 5<span class="elsevierStyleHsp" style=""></span>mm. The lesions are initially atrophic and are found on the dorsum of the hands and feet and can extend proximally with progressive darkening aggravated by exposure to sunlight. They rarely affect the face and are accompanied by palmoplantar pits and interrupted palmar creases, and there have been isolated reports of localized alopecia and absence of the distal phalanges of the toes. Dermoscopy shows the pigmentation to have a fine network of nonspecific reticulate brown pigment and the palmoplantar pits to have brown spots.<a class="elsevierStyleCrossRef" href="#bib0060"><span class="elsevierStyleSup">2</span></a> Histopathology reveals atrophy of the epidermis, elongation, and increased melanin on the interpapillary ridges, with scarce perivascular lymphocytic infiltrate, and an increased number of DOPA-positive basal melanocytes.<a class="elsevierStyleCrossRef" href="#bib0070"><span class="elsevierStyleSup">4</span></a></p><p id="par0025" class="elsevierStylePara elsevierViewall">There is some debate over whether RAPK, Dowling-Degos disease, Haber syndrome, and reticulate acropigmentation of Dohi are variants of the same disease, since their clinical and histologic characteristics overlap to some extent, mainly in Dowling-Degos disease and RAPK. The exception is Galli-Galli disease, in which suprabasal acantholysis can be observed.<a class="elsevierStyleCrossRefs" href="#bib0065"><span class="elsevierStyleSup">3,4</span></a> Dowling-Degos disease is autosomal dominant, more commonly affects adult women, and manifests with reticulate pigmentation and brown hyperkeratotic papules mainly on flexures and the trunk. It may be accompanied by comedones on the face and neck, perioral pitting, and facial scars, and even epidermal cysts, suppurative hidradenitis, seborrheic keratosis, pilonidal cysts, and tumors such as keratoacanthoma and squamous cell carcinoma. Histologically, it is similar to RAPK, although with more pronounced follicular involvement. Recent genetic studies indicate that they are different disorders, although this issue remains unresolved. In Dowling-Degos disease, there have been reports of mutations in the keratin 5 gene (<span class="elsevierStyleItalic">KRT5</span>) and, subsequently, in the protein O-fucosyltransferase 1 gene (<span class="elsevierStyleItalic">POFUT1</span>) and protein O-glucosyltransferase 1 protein gene (<span class="elsevierStyleItalic">POGLUT1</span>), which overlaps clinically with RAPK.<a class="elsevierStyleCrossRef" href="#bib0090"><span class="elsevierStyleSup">8</span></a> In 2013, several mutations were detected in the <span class="elsevierStyleItalic">ADAM10</span> gene in Japanese families with RAPK,<a class="elsevierStyleCrossRef" href="#bib0075"><span class="elsevierStyleSup">5</span></a> and, more recently, in other cases.<a class="elsevierStyleCrossRefs" href="#bib0080"><span class="elsevierStyleSup">6,7</span></a><span class="elsevierStyleItalic">ADAM10</span> codes for a disintegrin and metalloprotease, a member of the a disintegrin and metalloprotease family, which has numerous biologic functions and is expressed in the human epidermis, melanoma cells, and keratinocytes. In mice, its mutation is associated with freckle-like pigmentation.<a class="elsevierStyleCrossRef" href="#bib0075"><span class="elsevierStyleSup">5</span></a></p><p id="par0030" class="elsevierStylePara elsevierViewall">Furthermore, dermal melanocytosis comprises a group of benign congenital and—less frequently—acquired disorders characterized by the presence of dendritic melanocytes in the dermis. They are more common in Asian and African women and are unusual in white individuals. They comprise nevus of Ota, nevus of Ito, Mongolian spots, and dermal melanocytic hamartoma. Dermal melanocytosis rarely becomes malignant, with barely 4 cases of nevus of Ito.<a class="elsevierStyleCrossRef" href="#bib0095"><span class="elsevierStyleSup">9</span></a> Moreover, a case of Dowling-Degos disease and metastatic amelanotic melanoma has been reported.<a class="elsevierStyleCrossRef" href="#bib0100"><span class="elsevierStyleSup">10</span></a> To date, RAPK has not been reported to occur alongside other melanocytic disorders. There is no proof that RAPK and nevus of Ito are related, since, although both are pigmentation disorders, they are different. Thus, in dermal melanocytosis there is a proliferation of dermal melanocytes, whereas in RAPK, electron microscopy reveals an increase in the number of melanosomes in lesional melanocytes and keratinocytes.<a class="elsevierStyleCrossRef" href="#bib0080"><span class="elsevierStyleSup">6</span></a> The <span class="elsevierStyleItalic">ADAM10</span> mutation has not been studied to date in dermal melanocytosis.</p><p id="par0035" class="elsevierStylePara elsevierViewall">We present a case of RAPK and nevus of Ito in a white woman. This association has not previously been reported. Both conditions are more common in Asian individuals.</p><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0005">Conflicts of Interest</span><p id="par0040" class="elsevierStylePara elsevierViewall">The authors declare that they have no conflicts of interest.</p></span></span>" "textoCompletoSecciones" => array:1 [ "secciones" => array:3 [ 0 => array:2 [ "identificador" => "sec0005" "titulo" => "Conflicts of Interest" ] 1 => array:2 [ "identificador" => "xack297047" "titulo" => "Acknowledgments" ] 2 => array:1 [ "titulo" => "References" ] ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "NotaPie" => array:1 [ 0 => array:2 [ "etiqueta" => "☆" "nota" => "<p class="elsevierStyleNotepara" id="npar0005">Please cite this article as: García-Arpa M. Acropigmentación reticulada de Kitamura y nevus de Ito. Actas Dermosifiliogr. 2017;108:675–677.</p>" ] ] "multimedia" => array:3 [ 0 => array:7 [ "identificador" => "fig0005" "etiqueta" => "Figure 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 1025 "Ancho" => 2267 "Tamanyo" => 304049 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Lentiginous brown mottled pigmentation on the dorsum of the hands (A) and on the anterior aspect of the wrists (B).</p>" ] ] 1 => array:7 [ "identificador" => "fig0010" "etiqueta" => "Figure 2" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr2.jpeg" "Alto" => 965 "Ancho" => 2133 "Tamanyo" => 230708 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Noninfiltrated bluish macular plaque with no nodules and irregular borders and peripheral brown areas on the center of the back (13.5<span class="elsevierStyleHsp" style=""></span>×<span class="elsevierStyleHsp" style=""></span>10.5<span class="elsevierStyleHsp" style=""></span>cm) (A) and with less evident grayish-blue coloring on the right hemithorax (B).</p>" ] ] 2 => array:7 [ "identificador" => "fig0015" "etiqueta" => "Figure 3" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr3.jpeg" "Alto" => 827 "Ancho" => 2133 "Tamanyo" => 453436 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">A, Findings from a biopsy specimen taken from the wrist. Note the lentiginous epidermal hyperplasia with hyperpigmented bulbous projections of the epidermal rete ridges and increased basal melanocytes (hematoxylin-eosin [H-E], original magnification ×10; detail (inset), original magnification ×40). B, Findings from a biopsy specimen taken from the back. Notice the dendritic melanocytes in the reticular and papillary dermis and hyperpigmentation of the basal layer of the epidermis (H-E, original magnification ×20).</p>" ] ] ] "bibliografia" => array:2 [ "titulo" => "References" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:10 [ 0 => array:3 [ "identificador" => "bib0055" "etiqueta" => "1" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Reticulate pigmentary disorders" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "K. Sardana" 1 => "K. Goel" 2 => "S. Chugh" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.4103/0378-6323.104665" "Revista" => array:6 [ "tituloSerie" => "Indian J Dermatol Venereol Leprol." "fecha" => "2013" "volumen" => "79" "paginaInicial" => "17" "paginaFinal" => "29" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/23254725" "web" => "Medline" ] ] ] ] ] ] ] ] 1 => array:3 [ "identificador" => "bib0060" "etiqueta" => "2" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Characteristic findings of handprint and dermoscopy in reticulate acropigmentation of Kitamura" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "H. Koguchi" 1 => "H. Ujiie" 2 => "S. Aoyagi" 3 => "R. Osawa" 4 => "H. Shimizu" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1111/ced.12191" "Revista" => array:6 [ "tituloSerie" => "Clin Exp Dermatol." "fecha" => "2014" "volumen" => "39" "paginaInicial" => "85" "paginaFinal" => "87" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/23746125" "web" => "Medline" ] ] ] ] ] ] ] ] 2 => array:3 [ "identificador" => "bib0065" "etiqueta" => "3" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Dowling-Degos disease with reticulate acropigmentation of Kitamura: Extended spectrum of a single entity" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "S.G. Rathoriva" 1 => "S.S. Soni" 2 => "D. Asati" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.4103/2229-5178.174307" "Revista" => array:6 [ "tituloSerie" => "Indian Dermatol Online J." "fecha" => "2016" "volumen" => "7" "paginaInicial" => "32" "paginaFinal" => "35" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/26955585" "web" => "Medline" ] ] ] ] ] ] ] ] 3 => array:3 [ "identificador" => "bib0070" "etiqueta" => "4" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "A case of reticulate acropigmentation of Kitamura: Dowling Degos disease overlap with unusual clinical manifestations" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "B. Vasudevan" 1 => "R. Verma" 2 => "S. Badwal" 3 => "V. Pragasam" 4 => "N. Moorchung" 5 => "A. Badad" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.4103/0019-5154.131408" "Revista" => array:6 [ "tituloSerie" => "Indian J Dermatol." "fecha" => "2014" "volumen" => "59" "paginaInicial" => "290" "paginaFinal" => "292" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/24891663" "web" => "Medline" ] ] ] ] ] ] ] ] 4 => array:3 [ "identificador" => "bib0075" "etiqueta" => "5" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Whole-exome sequencing identifies ADAM10 mutations as a cause of reticulate acropigmentation of Kitamura, a clinical entity distinct from Dowling-Degos disease" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "M. Kono" 1 => "K. Sugiura" 2 => "M. Suganuma" 3 => "M. Hayashi" 4 => "H. Takama" 5 => "T. Suzuki" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1093/hmg/ddt207" "Revista" => array:6 [ "tituloSerie" => "Hum Mol Genet." "fecha" => "2013" "volumen" => "22" "paginaInicial" => "3524" "paginaFinal" => "3533" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/23666529" "web" => "Medline" ] ] ] ] ] ] ] ] 5 => array:3 [ "identificador" => "bib0080" "etiqueta" => "6" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Behavior of melanocytes and keratinocytes in reticulate acropigmentation of Kitamura" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "K. Okamura" 1 => "Y. Abe" 2 => "Y. Araki" 3 => "Y. Hozumi" 4 => "M. Kawaguchi" 5 => "T. Suzuki" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1111/pcmr.12453" "Revista" => array:6 [ "tituloSerie" => "Pigment Cell Melanoma Res." "fecha" => "2016" "volumen" => "29" "paginaInicial" => "243" "paginaFinal" => "246" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/26708207" "web" => "Medline" ] ] ] ] ] ] ] ] 6 => array:3 [ "identificador" => "bib0085" "etiqueta" => "7" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Reticulate acropigmentation of Kitamura with a novel ADAM10 mutation: A case report" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "M. Tsutsumi" 1 => "M. Kono" 2 => "M. Akiyama" 3 => "N. Katoh" 4 => "N. Nakai" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1111/1346-8138.13308" "Revista" => array:6 [ "tituloSerie" => "J Dermatol." "fecha" => "2016" "volumen" => "43" "paginaInicial" => "963" "paginaFinal" => "965" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/26892935" "web" => "Medline" ] ] ] ] ] ] ] ] 7 => array:3 [ "identificador" => "bib0090" "etiqueta" => "8" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Pathogenicity of POFUT1 in Dowling-Degos disease: Additional mutations and clinical overlap with reticulate acropigmentation of Kitamura" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "F.B. Basmanav" 1 => "G. Fritz" 2 => "G.G. Lestringant" 3 => "D. Pachat" 4 => "S. Hoffjan" 5 => "J. Fischer" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1038/jid.2014.406" "Revista" => array:6 [ "tituloSerie" => "J Invest Dermatol." "fecha" => "2015" "volumen" => "135" "paginaInicial" => "615" "paginaFinal" => "618" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/25229252" "web" => "Medline" ] ] ] ] ] ] ] ] 8 => array:3 [ "identificador" => "bib0095" "etiqueta" => "9" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Melanoma arising in a nevus of Ito: Novel genetic mutations and a review of the literature on cutaneous malignant transformation of dermal melanocytosis" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "J.Y. Tse" 1 => "B.E. Walls" 2 => "H. Pomerantz" 3 => "C.H. Yoon" 4 => "E.I. Buchbinder" 5 => "A.E. Werchniak" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1111/cup.12568" "Revista" => array:6 [ "tituloSerie" => "J Cutan Pathol." "fecha" => "2016" "volumen" => "43" "paginaInicial" => "57" "paginaFinal" => "63" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/26260725" "web" => "Medline" ] ] ] ] ] ] ] ] 9 => array:3 [ "identificador" => "bib0100" "etiqueta" => "10" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Dowling-Degos disease and malignant melanoma: Association or mere coincidence?" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "V. Gupta" 1 => "K. Sahni" 2 => "P. Khute" 3 => "V.K. Sharma" 4 => "M.F. Ali" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.4103/0378-6323.168334" "Revista" => array:6 [ "tituloSerie" => "Indian J Dermatol Venereol Leprol." "fecha" => "2015" "volumen" => "81" "paginaInicial" => "627" "paginaFinal" => "628" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/26515850" "web" => "Medline" ] ] ] ] ] ] ] ] ] ] ] ] "agradecimientos" => array:1 [ 0 => array:4 [ "identificador" => "xack297047" "titulo" => "Acknowledgments" "texto" => "<p id="par0045" class="elsevierStylePara elsevierViewall">We are grateful to Dr. Juan Luis Santiago Sánchez-Mateos for his help in this study.</p>" "vista" => "all" ] ] ] "idiomaDefecto" => "en" "url" => "/15782190/0000010800000007/v2_201708291348/S1578219017302159/v2_201708291348/en/main.assets" "Apartado" => array:4 [ "identificador" => "6157" "tipo" => "SECCION" "en" => array:2 [ "titulo" => "Case and Research Letters" "idiomaDefecto" => true ] "idiomaDefecto" => "en" ] "PDF" => "https://static.elsevier.es/multimedia/15782190/0000010800000007/v2_201708291348/S1578219017302159/v2_201708291348/en/main.pdf?idApp=UINPBA000044&text.app=https://actasdermo.org/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219017302159?idApp=UINPBA000044" ]
| año/Mes | Html | Total | |
|---|---|---|---|
| 2024 Noviembre | 39 | 14 | 53 |
| 2024 Octubre | 210 | 53 | 263 |
| 2024 Septiembre | 165 | 54 | 219 |
| 2024 Agosto | 178 | 99 | 277 |
| 2024 Julio | 171 | 47 | 218 |
| 2024 Junio | 166 | 53 | 219 |
| 2024 Mayo | 164 | 47 | 211 |
| 2024 Abril | 153 | 29 | 182 |
| 2024 Marzo | 166 | 33 | 199 |
| 2024 Febrero | 126 | 38 | 164 |
| 2024 Enero | 146 | 40 | 186 |
| 2023 Diciembre | 214 | 24 | 238 |
| 2023 Noviembre | 271 | 28 | 299 |
| 2023 Octubre | 232 | 21 | 253 |
| 2023 Septiembre | 273 | 31 | 304 |
| 2023 Agosto | 159 | 20 | 179 |
| 2023 Julio | 107 | 46 | 153 |
| 2023 Junio | 116 | 29 | 145 |
| 2023 Mayo | 139 | 42 | 181 |
| 2023 Abril | 118 | 27 | 145 |
| 2023 Marzo | 122 | 37 | 159 |
| 2023 Febrero | 121 | 29 | 150 |
| 2023 Enero | 125 | 42 | 167 |
| 2022 Diciembre | 114 | 51 | 165 |
| 2022 Noviembre | 75 | 30 | 105 |
| 2022 Octubre | 51 | 29 | 80 |
| 2022 Septiembre | 53 | 40 | 93 |
| 2022 Agosto | 75 | 44 | 119 |
| 2022 Julio | 52 | 43 | 95 |
| 2022 Junio | 50 | 38 | 88 |
| 2022 Mayo | 169 | 50 | 219 |
| 2022 Abril | 198 | 61 | 259 |
| 2022 Marzo | 218 | 79 | 297 |
| 2022 Febrero | 188 | 58 | 246 |
| 2022 Enero | 193 | 68 | 261 |
| 2021 Diciembre | 131 | 64 | 195 |
| 2021 Noviembre | 151 | 61 | 212 |
| 2021 Octubre | 164 | 74 | 238 |
| 2021 Septiembre | 122 | 49 | 171 |
| 2021 Agosto | 131 | 49 | 180 |
| 2021 Julio | 138 | 46 | 184 |
| 2021 Junio | 136 | 50 | 186 |
| 2021 Mayo | 128 | 75 | 203 |
| 2021 Abril | 254 | 96 | 350 |
| 2021 Marzo | 192 | 60 | 252 |
| 2021 Febrero | 133 | 35 | 168 |
| 2021 Enero | 116 | 38 | 154 |
| 2020 Diciembre | 107 | 37 | 144 |
| 2020 Noviembre | 83 | 37 | 120 |
| 2020 Octubre | 75 | 27 | 102 |
| 2020 Septiembre | 72 | 34 | 106 |
| 2020 Agosto | 45 | 38 | 83 |
| 2020 Julio | 54 | 32 | 86 |
| 2020 Junio | 56 | 59 | 115 |
| 2020 Mayo | 27 | 36 | 63 |
| 2020 Abril | 33 | 16 | 49 |
| 2020 Marzo | 23 | 13 | 36 |
| 2020 Febrero | 6 | 0 | 6 |
| 2020 Enero | 4 | 0 | 4 |
| 2019 Diciembre | 7 | 0 | 7 |
| 2019 Noviembre | 2 | 0 | 2 |
| 2019 Septiembre | 8 | 0 | 8 |
| 2019 Agosto | 4 | 0 | 4 |
| 2019 Julio | 4 | 0 | 4 |
| 2019 Junio | 6 | 0 | 6 |
| 2019 Mayo | 3 | 0 | 3 |
| 2019 Abril | 2 | 0 | 2 |
| 2019 Marzo | 2 | 0 | 2 |
| 2019 Febrero | 3 | 0 | 3 |
| 2019 Enero | 4 | 0 | 4 |
| 2018 Diciembre | 2 | 0 | 2 |
| 2018 Octubre | 4 | 0 | 4 |
| 2018 Septiembre | 3 | 0 | 3 |
| 2018 Febrero | 33 | 9 | 42 |
| 2018 Enero | 43 | 9 | 52 |
| 2017 Diciembre | 51 | 9 | 60 |
| 2017 Noviembre | 36 | 6 | 42 |
| 2017 Octubre | 40 | 15 | 55 |
| 2017 Septiembre | 210 | 24 | 234 |
| 2017 Agosto | 44 | 24 | 68 |
| 2017 Julio | 4 | 11 | 15 |
Mostrar todo
