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On February 1&#44; 2016&#44; the World Health Organization declared ZIKV infection a Public Health Emergency of International Concern&#46; One week later&#44; the Centers for Disease Control and Prevention upgraded its response to the outbreak to Level 1 activation&#44; the agency&#39;s highest level&#46; We present the case of a patient diagnosed with ZIKV infection in our center&#46; Our aim is to increase awareness of this emerging arbovirus among dermatologists&#46; Given the mainly cutaneous symptoms of the infection and the intensity of travel and migratory flows from Latin America&#44; it seems highly likely that we will be diagnosing ZIKV in the coming months&#46;</p><p id="par0010" class="elsevierStylePara elsevierViewall">A 25-year-old woman from the Dominican Republic with no personal history of interest who had been living in Spain for 8 years was referred to the dermatology emergency department for assessment of a pruriginous exanthem that had started 48<span class="elsevierStyleHsp" style=""></span>hours previously and was extending down her body&#46; She also had intense asthenia&#44; sensation of poor temperature regulation&#44; mild joint and muscle pain&#44; headache&#44; and ocular pruritus&#46; Physical examination revealed bilateral malar erythema and edema&#44; together with marked conjunctival injection &#40;<a class="elsevierStyleCrossRefs" href="#fig0005">Figures 1 and 2</a>&#41; and subtle generalized micropapular exanthema with follicular accentuation &#40;<a class="elsevierStyleCrossRef" href="#fig0015">Figure 3</a>&#41;&#46; The blood workup revealed only slightly altered cytolysis in the liver&#46; The fact that she had spent a month in her home country and arrived in Spain 12<span class="elsevierStyleHsp" style=""></span>hours before the onset of symptoms led us to suspect ZIKV infection&#46; Therefore&#44; we ordered serology tests and nucleic acid testing in serum and urine using reverse transcriptase polymerase chain reaction &#40;RT-PCR&#41; to detect ZIKV&#46; We also requested a workup for dengue virus and chikungunya virus and the usual protocol for exanthematous viruses&#46; The result of the pregnancy test was negative&#46; Histopathology of the skin revealed a mild superficial perivascular lymphocytic infiltrate&#46; The symptoms resolved completely 6 days after onset&#46; RT-PCR in urine and serum was positive for ZIKV in samples collected at 48<span class="elsevierStyleHsp" style=""></span>hours from onset&#46; The results of serology testing were negative&#46;</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><elsevierMultimedia ident="fig0010"></elsevierMultimedia><elsevierMultimedia ident="fig0015"></elsevierMultimedia><p id="par0015" class="elsevierStylePara elsevierViewall">ZIKV is a single-stranded RNA virus belonging to the genus <span class="elsevierStyleItalic">Flavivirus</span> of the Flaviviridae family&#46; It is transmitted mainly by bites from mosquitos of the <span class="elsevierStyleItalic">Aedes</span> genus&#44; in most cases <span class="elsevierStyleItalic">A aegypti</span> &#40;although it is also carried by other species&#44; including <span class="elsevierStyleItalic">A albopictus</span>&#41;&#46; As with other arboviruses&#44; vector-independent routes of transmission have been identified &#40;eg&#44; vertical and transfusional&#41;&#46;<a class="elsevierStyleCrossRef" href="#bib0040"><span class="elsevierStyleSup">1</span></a> Remarkably&#44; in contrast with other arboviruses&#44; sexual transmission has also been documented&#46;<a class="elsevierStyleCrossRef" href="#bib0045"><span class="elsevierStyleSup">2</span></a> It remains to be determined whether there is a risk of transmission via other fluids where viral RNA has been detected&#44; such as saliva or breastmilk&#46;<a class="elsevierStyleCrossRefs" href="#bib0050"><span class="elsevierStyleSup">3&#44;4</span></a></p><p id="par0020" class="elsevierStylePara elsevierViewall">It is estimated that only 1 in 5 infected persons develops clinical manifestations&#44; which are generally mild and self-limiting&#46; After an incubation period lasting between 3 and 12 days&#44; the typical manifestations are pruriginous maculopapular rash that extends down the body&#44; mild fever&#44; mild pain affecting mainly the small joints of the hands and feet&#44; and nonpurulent conjunctivitis&#46; The manifestations last 2 to 7 days&#46;<a class="elsevierStyleCrossRef" href="#bib0060"><span class="elsevierStyleSup">5</span></a> Although the clinical picture coincides with that of other viruses transmitted by the same vector&#44; such as dengue or chikungunya&#44; certain characteristics can orient us toward the causative agent&#44; namely&#44; predominance of rash with little involvement of the patient&#39;s general status in ZIKV infection&#44; persistent joint pain in chikungunya infection&#44; and the classic picture of rash respecting specific areas of skin&#44; thrombocytopenia&#44; and bleeding complications in dengue&#46; The absence of pathognomonic findings&#44; however&#44; necessitates a microbiologic diagnosis based on the detection of viral RNA using RT-PCR assay in serum during the first 5 days with symptoms or in urine for up to 10-15 days&#46; This study can be extended to cerebrospinal fluid in patients with neurological symptoms&#46;<a class="elsevierStyleCrossRef" href="#bib0065"><span class="elsevierStyleSup">6</span></a> RT-PCR assay is followed by serology testing&#46; This approach is of particular interest in pregnant women&#44; although it is limited because of cross-reactivity with other flaviviruses&#46; Available evidence indicates that ZIKV infection can confer prolonged immunity&#46;</p><p id="par0025" class="elsevierStylePara elsevierViewall">Up to mid-March 2016&#44; the Spanish National Microbiology Center had confirmed 43 cases of ZIKV infection in Spain&#44; all of which were imported&#46; However&#44; the presence of <span class="elsevierStyleItalic">A&#160;albopictus</span> &#40;commonly known as the tiger mosquito&#41;<a class="elsevierStyleCrossRef" href="#bib0070"><span class="elsevierStyleSup">7</span></a> along the Mediterranean coast and in the Basque Country and Aragon enables autochthonous transmission of ZIKV in Spain&#44; mainly during summer and winter&#44; which is when vector activity is most intense and more people travel from epidemic areas&#46;</p><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0005">Conflicts of Interest</span><p id="par0030" class="elsevierStylePara elsevierViewall">The authors declare that they have no conflicts of interest&#46;</p></span></span>"
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                      "titulo" => "Zika fever and congenital Zika syndrome&#58; An unexpected emerging arboviral disease"
                      "autores" => array:1 [
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                          "etal" => false
                          "autores" => array:5 [
                            0 => "J&#46;F&#46; Chan"
                            1 => "G&#46;K&#46; Choi"
                            2 => "C&#46;C&#46; Yip"
                            3 => "V&#46;C&#46; Cheng"
                            4 => "K&#46;Y&#46; Yuen"
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                        "paginaFinal" => "524"
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                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/26940504"
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            ]
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                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Potential sexual transmission of Zika virus"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "D&#46; Musso"
                            1 => "C&#46; Roche"
                            2 => "E&#46; Robin"
                            3 => "T&#46; Nhan"
                            4 => "A&#46; Teissier"
                            5 => "V&#46;M&#46; Cao-Lormeau"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.3201/eid2102.141363"
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                        "tituloSerie" => "Emerg Infect Dis"
                        "fecha" => "2015"
                        "volumen" => "21"
                        "paginaInicial" => "359"
                        "paginaFinal" => "361"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/25625872"
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                0 => array:3 [
                  "comentario" => "pii&#58; 20751"
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Evidence of perinatal transmission of Zika virus&#44; French Polynesia&#44; December 2013 and February 2014"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
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                            1 => "S&#46; Lastere"
                            2 => "A&#46; Teissier"
                            3 => "V&#46; Cao-Lormeau"
                            4 => "D&#46; Musso"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:3 [
                        "tituloSerie" => "Euro Surveill"
                        "fecha" => "2014"
                        "volumen" => "19"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            3 => array:3 [
              "identificador" => "bib0055"
              "etiqueta" => "4"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Detection of Zika virus in saliva"
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                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "D&#46; Musso"
                            1 => "C&#46; Roche"
                            2 => "T&#46;X&#46; Nhan"
                            3 => "E&#46; Robin"
                            4 => "A&#46; Teissier"
                            5 => "V&#46;M&#46; Cao-Lormeau"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1016/j.jcv.2015.04.021"
                      "Revista" => array:6 [
                        "tituloSerie" => "J Clin Virol"
                        "fecha" => "2015"
                        "volumen" => "68"
                        "paginaInicial" => "53"
                        "paginaFinal" => "55"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/26071336"
                            "web" => "Medline"
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                      ]
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                ]
              ]
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                    0 => array:2 [
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                        0 => array:2 [
                          "etal" => false
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                            0 => "J&#46; Heukelbach"
                            1 => "C&#46;H&#46; Alencar"
                            2 => "A&#46;A&#46; Kelvin"
                            3 => "W&#46;K&#46; de Oliveira"
                            4 => "L&#46; Pamplona de G&#243;es Cavalcanti"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "J Infect Dev Ctries"
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                        "volumen" => "10"
                        "paginaInicial" => "116"
                        "paginaFinal" => "120"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/26927450"
                            "web" => "Medline"
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                      ]
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                  ]
                ]
              ]
            ]
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              "identificador" => "bib0065"
              "etiqueta" => "6"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Detection of Zika virus in urine"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "A&#46;C&#46; Gourinat"
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                            3 => "C&#46; Goarant"
                            4 => "M&#46; Dupont-Rouzeyrol"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
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                        "paginaInicial" => "84"
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                        "link" => array:1 [
                          0 => array:2 [
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                  ]
                ]
              ]
            ]
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              "etiqueta" => "7"
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                0 => array:2 [
                  "contribucion" => array:1 [
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                      "titulo" => "Dispersion of <span class="elsevierStyleItalic">Aedes albopictus</span> in the Spanish Mediterranean Area"
                      "autores" => array:1 [
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                          "etal" => true
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                      ]
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                        "volumen" => "24"
                        "paginaInicial" => "637"
                        "paginaFinal" => "640"
                        "link" => array:1 [
                          0 => array:2 [
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Case and Research Letters
Zika Virus Infection: An Emerging Disease the Dermatologist Must Know About
Infección por virus del Zika: una enfermedad emergente que el dermatólogo debe conocer
S. Burillo-Martíneza,
Autor para correspondencia
sburillo@hotmail.com

Corresponding author.
, M. Fernández-Ruizb, A. Pérez-Rivillac, C. Zarco-Olivoa
a Servicio de Dermatología, Hospital Universitario 12 de Octubre, Instituto de Investigación Hospital 12 de Octubre (i+12), Madrid, Spain
b Unidad de Enfermedades Infecciosas, Hospital Universitario 12 de Octubre, Instituto de Investigación Hospital 12 de Octubre (i+12), Madrid, Spain
c Servicio de Microbiología, Hospital Universitario 12 de Octubre, Instituto de Investigación Hospital 12 de Octubre (i+12), Madrid, Spain
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    "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">In contrast to infection by other arboviruses such as dengue virus&#44; which can cause potentially severe disease in humans&#44; infection by Zika virus &#40;ZIKV&#41; is generally benign and self-limiting&#44; with mainly asymptomatic episodes&#46; Recent epidemiological shifts in the geographic distribution of ZIKV&#44; however&#44; have raised health care alarms around the world because of the possible association between ZIKV infection and congenital malformations&#44; particularly microcephaly&#44; and neurologic disorders&#44; including Guillain-Barr&#233; syndrome&#46; Although the discovery of the virus in the Zika forest in Uganda dates back to 1947&#44; fewer than 20 cases of ZIKV infection had been reported in humans up to 2007&#46; Preceded by the outbreaks on the island of Yap in Micronesia in 2007 and in French Polynesia in 2013&#44; the epidemic that started in May 2015 in Latin America continues to expand uncontrolled&#46; On February 1&#44; 2016&#44; the World Health Organization declared ZIKV infection a Public Health Emergency of International Concern&#46; One week later&#44; the Centers for Disease Control and Prevention upgraded its response to the outbreak to Level 1 activation&#44; the agency&#39;s highest level&#46; We present the case of a patient diagnosed with ZIKV infection in our center&#46; Our aim is to increase awareness of this emerging arbovirus among dermatologists&#46; Given the mainly cutaneous symptoms of the infection and the intensity of travel and migratory flows from Latin America&#44; it seems highly likely that we will be diagnosing ZIKV in the coming months&#46;</p><p id="par0010" class="elsevierStylePara elsevierViewall">A 25-year-old woman from the Dominican Republic with no personal history of interest who had been living in Spain for 8 years was referred to the dermatology emergency department for assessment of a pruriginous exanthem that had started 48<span class="elsevierStyleHsp" style=""></span>hours previously and was extending down her body&#46; She also had intense asthenia&#44; sensation of poor temperature regulation&#44; mild joint and muscle pain&#44; headache&#44; and ocular pruritus&#46; Physical examination revealed bilateral malar erythema and edema&#44; together with marked conjunctival injection &#40;<a class="elsevierStyleCrossRefs" href="#fig0005">Figures 1 and 2</a>&#41; and subtle generalized micropapular exanthema with follicular accentuation &#40;<a class="elsevierStyleCrossRef" href="#fig0015">Figure 3</a>&#41;&#46; The blood workup revealed only slightly altered cytolysis in the liver&#46; The fact that she had spent a month in her home country and arrived in Spain 12<span class="elsevierStyleHsp" style=""></span>hours before the onset of symptoms led us to suspect ZIKV infection&#46; Therefore&#44; we ordered serology tests and nucleic acid testing in serum and urine using reverse transcriptase polymerase chain reaction &#40;RT-PCR&#41; to detect ZIKV&#46; We also requested a workup for dengue virus and chikungunya virus and the usual protocol for exanthematous viruses&#46; The result of the pregnancy test was negative&#46; Histopathology of the skin revealed a mild superficial perivascular lymphocytic infiltrate&#46; The symptoms resolved completely 6 days after onset&#46; RT-PCR in urine and serum was positive for ZIKV in samples collected at 48<span class="elsevierStyleHsp" style=""></span>hours from onset&#46; The results of serology testing were negative&#46;</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><elsevierMultimedia ident="fig0010"></elsevierMultimedia><elsevierMultimedia ident="fig0015"></elsevierMultimedia><p id="par0015" class="elsevierStylePara elsevierViewall">ZIKV is a single-stranded RNA virus belonging to the genus <span class="elsevierStyleItalic">Flavivirus</span> of the Flaviviridae family&#46; It is transmitted mainly by bites from mosquitos of the <span class="elsevierStyleItalic">Aedes</span> genus&#44; in most cases <span class="elsevierStyleItalic">A aegypti</span> &#40;although it is also carried by other species&#44; including <span class="elsevierStyleItalic">A albopictus</span>&#41;&#46; As with other arboviruses&#44; vector-independent routes of transmission have been identified &#40;eg&#44; vertical and transfusional&#41;&#46;<a class="elsevierStyleCrossRef" href="#bib0040"><span class="elsevierStyleSup">1</span></a> Remarkably&#44; in contrast with other arboviruses&#44; sexual transmission has also been documented&#46;<a class="elsevierStyleCrossRef" href="#bib0045"><span class="elsevierStyleSup">2</span></a> It remains to be determined whether there is a risk of transmission via other fluids where viral RNA has been detected&#44; such as saliva or breastmilk&#46;<a class="elsevierStyleCrossRefs" href="#bib0050"><span class="elsevierStyleSup">3&#44;4</span></a></p><p id="par0020" class="elsevierStylePara elsevierViewall">It is estimated that only 1 in 5 infected persons develops clinical manifestations&#44; which are generally mild and self-limiting&#46; After an incubation period lasting between 3 and 12 days&#44; the typical manifestations are pruriginous maculopapular rash that extends down the body&#44; mild fever&#44; mild pain affecting mainly the small joints of the hands and feet&#44; and nonpurulent conjunctivitis&#46; The manifestations last 2 to 7 days&#46;<a class="elsevierStyleCrossRef" href="#bib0060"><span class="elsevierStyleSup">5</span></a> Although the clinical picture coincides with that of other viruses transmitted by the same vector&#44; such as dengue or chikungunya&#44; certain characteristics can orient us toward the causative agent&#44; namely&#44; predominance of rash with little involvement of the patient&#39;s general status in ZIKV infection&#44; persistent joint pain in chikungunya infection&#44; and the classic picture of rash respecting specific areas of skin&#44; thrombocytopenia&#44; and bleeding complications in dengue&#46; The absence of pathognomonic findings&#44; however&#44; necessitates a microbiologic diagnosis based on the detection of viral RNA using RT-PCR assay in serum during the first 5 days with symptoms or in urine for up to 10-15 days&#46; This study can be extended to cerebrospinal fluid in patients with neurological symptoms&#46;<a class="elsevierStyleCrossRef" href="#bib0065"><span class="elsevierStyleSup">6</span></a> RT-PCR assay is followed by serology testing&#46; This approach is of particular interest in pregnant women&#44; although it is limited because of cross-reactivity with other flaviviruses&#46; Available evidence indicates that ZIKV infection can confer prolonged immunity&#46;</p><p id="par0025" class="elsevierStylePara elsevierViewall">Up to mid-March 2016&#44; the Spanish National Microbiology Center had confirmed 43 cases of ZIKV infection in Spain&#44; all of which were imported&#46; However&#44; the presence of <span class="elsevierStyleItalic">A&#160;albopictus</span> &#40;commonly known as the tiger mosquito&#41;<a class="elsevierStyleCrossRef" href="#bib0070"><span class="elsevierStyleSup">7</span></a> along the Mediterranean coast and in the Basque Country and Aragon enables autochthonous transmission of ZIKV in Spain&#44; mainly during summer and winter&#44; which is when vector activity is most intense and more people travel from epidemic areas&#46;</p><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0005">Conflicts of Interest</span><p id="par0030" class="elsevierStylePara elsevierViewall">The authors declare that they have no conflicts of interest&#46;</p></span></span>"
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Información del artículo
ISSN: 15782190
Idioma original: Inglés
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