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    "textoCompleto" => "<span class="elsevierStyleSections"><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0005">Medical History</span><p id="par0005" class="elsevierStylePara elsevierViewall">A 32-year-old woman consulted for an asymptomatic lesion that had been present on the mid sternum for 12 years&#44; unchanged in size or shape&#46; She was concerned about the cosmetic effect of the lesion&#44; as it looked like a surgical sternotomy scar&#46; The only relevant background was a scoliosis that had required treatment using a corset during childhood&#46;</p></span><span id="sec0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0010">Physical Examination</span><p id="par0010" class="elsevierStylePara elsevierViewall">A linear midline lesion of approximately 5<span class="elsevierStyleHsp" style=""></span>cm in length was observed&#46; It was formed of papular lesions with central follicular openings that simulated open comedos arranged in line&#44; one after the other &#40;<a class="elsevierStyleCrossRef" href="#fig0005">Fig&#46; 1</a>&#41;&#46;</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia></span><span id="sec0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0015">Additional Tests</span><p id="par0015" class="elsevierStylePara elsevierViewall">Epiluminiscence examination made the follicular openings clearly visible&#59; they were found to be full of a homogeneous brownish material &#40;<a class="elsevierStyleCrossRef" href="#fig0010">Fig&#46; 2</a>&#41;&#46;</p><elsevierMultimedia ident="fig0010"></elsevierMultimedia><p id="par0020" class="elsevierStylePara elsevierViewall">Histology revealed infundibular dilatations&#44; with no hairs&#44; in the form of contiguous epidermal invaginations into the dermis&#44; filled by laminar keratin &#40;<a class="elsevierStyleCrossRef" href="#fig0015">Fig&#46; 3</a>&#41;&#46;</p><elsevierMultimedia ident="fig0015"></elsevierMultimedia><p id="par0025" class="elsevierStylePara elsevierViewall">Chest x-ray revealed a moderate dorsolumbar scoliosis that had been partially corrected years earlier&#46;</p><p id="par0030" class="elsevierStylePara elsevierViewall">Ophthalmologic examination of the right eye revealed an asymptomatic subcapsular cataract&#44; which could have been of recent onset&#46;</p><p id="par0035" class="elsevierStylePara elsevierViewall">Neurologic examination was rigorously normal&#46;</p><p id="par0040" class="elsevierStylePara elsevierViewall">What Is Your Diagnosis&#63;</p><p id="par0045" class="elsevierStylePara elsevierViewall">Nevus comedonicus&#46;</p></span><span id="sec0020" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0020">Clinical Course and Treatment</span><p id="par0050" class="elsevierStylePara elsevierViewall">Treatment was started with 0&#46;1&#37; retinoic acid&#44; leading to a notable improvement within a few days&#44; leaving a barely perceptible residual lesion&#46;</p></span><span id="sec0025" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0025">Comment</span><p id="par0055" class="elsevierStylePara elsevierViewall">Nevus comedonicus is considered to be a variant of epidermal nevus&#46; It is formed of infundibular dilatations filled by keratin&#44; similar to typical comedos&#44; and it usually arises on the face and neck&#46; The prevalence of this condition is estimated at between 1 in 45&#160;000 and 1 in 100&#160;000 patients&#44; with no gender or racial differences&#46;<a class="elsevierStyleCrossRef" href="#bib0025"><span class="elsevierStyleSup">1</span></a> Most commonly it is present at birth or appears during infancy&#46; The typical presentation of these dilated follicles is grouped in a plaque or honeycomb distribution&#44; although we may observe other patterns&#58; unilateral or bilateral&#44; linear&#44; segmental&#44; or Blaschkoid&#46;<a class="elsevierStyleCrossRef" href="#bib0025"><span class="elsevierStyleSup">1</span></a> The clinical appearance is usually sufficient to make the diagnosis&#44; although epiluminescence can be useful&#44; as it can make follicles visible as papules with openings filled by brown-colored plugs&#59; the dermoscopic image of acne vulgaris would show numerous superficial comedos of light or dark brown or black color&#44; depending on the type of acne &#40;open or closed comedos&#41;&#46;<a class="elsevierStyleCrossRef" href="#bib0030"><span class="elsevierStyleSup">2</span></a> In case of doubt&#44; histology will confirm the diagnosis&#46;<a class="elsevierStyleCrossRef" href="#bib0025"><span class="elsevierStyleSup">1</span></a></p><p id="par0060" class="elsevierStylePara elsevierViewall">Nevus comedonicus can occur as an isolated finding<a class="elsevierStyleCrossRef" href="#bib0035"><span class="elsevierStyleSup">3</span></a> or&#44; more rarely&#44; be associated with ocular&#44; skeletal&#44; or central nervous system changes&#44; forming part of a neurocutaneous syndrome called nevus comedonicus syndrome&#46; The most common changes described in this syndrome are cataracts &#40;typically ipsilateral&#41;&#44; scoliosis&#44; vertebral fusions&#44; spina bifida&#44; and mental retardation&#44; although many and varied alterations have been reported in the literature&#46;<a class="elsevierStyleCrossRefs" href="#bib0025"><span class="elsevierStyleSup">1&#44;3&#44;4</span></a> The appearance of epithelial tumors within the lesion have also been reported&#44; in particular trichoepitheliomas&#44; syringocystadenoma papilliferum&#44; keratoacanthoma&#44; and&#44; more rarely&#44; basal cell and squamous cell carcinomas&#46;<a class="elsevierStyleCrossRef" href="#bib0025"><span class="elsevierStyleSup">1</span></a></p><p id="par0065" class="elsevierStylePara elsevierViewall">In the absence of complications or marked cosmetic alterations&#44; management is conservative&#46; First-line treatment is with keratolytics and topical retinoids&#46; Laser therapy or surgical excision can be considered in some cases&#46;<a class="elsevierStyleCrossRef" href="#bib0025"><span class="elsevierStyleSup">1</span></a> The possible associated diseases must be taken into account&#44; and periodic follow-up of the lesion should be performed to detect skin tumors&#46;</p><p id="par0070" class="elsevierStylePara elsevierViewall">In conclusion&#44; we have described the clinical and dermoscopic characteristics of a new case of linear nevus comedonicus of uncertain time since onset&#44; associated with moderate scoliosis and a mild subcapsular cataract&#46; Treatment with topical retinoids was effective&#46; The prevalence of moderate scoliosis and subcapsular cataract is high in the general population&#44; and this association may therefore be mere coincidence&#44; in which case this would not be nevus comedonicus syndrome&#46;</p></span><span id="sec0030" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0030">Conflicts of Interest</span><p id="par0075" class="elsevierStylePara elsevierViewall">The authors declare that they have no conflicts of interest&#46;</p></span></span>"
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                            2 => "K&#46; Semkova"
                            3 => "L&#46;A&#46; Dourmishev"
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                            5 => "U&#46; Wollina"
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                        "tituloSerie" => "Dermatol Ther"
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                          "etal" => false
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                            0 => "G&#46; Kami&#241;ska-Winciorek"
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                  ]
                  "host" => array:1 [
                    0 => array:1 [
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                        "fecha" => "2013"
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                            0 => "S&#46; Pavithra"
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                    0 => array:2 [
                      "doi" => "10.4103/0019-5154.91853"
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                        "tituloSerie" => "Indian J Dermatol"
                        "fecha" => "2011"
                        "volumen" => "56"
                        "paginaInicial" => "771"
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                      "titulo" => "The group of epidermal nevus syndromes&#46; Part I&#46; Well defined phenotypes"
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                      "doi" => "10.1016/j.jaad.2010.01.017"
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                        "fecha" => "2010"
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