se ha leído el artículo
array:24 [ "pii" => "S1578219016300099" "issn" => "15782190" "doi" => "10.1016/j.adengl.2016.02.023" "estado" => "S300" "fechaPublicacion" => "2016-05-01" "aid" => "1292" "copyright" => "AEDV" "copyrightAnyo" => "2015" "documento" => "simple-article" "crossmark" => 1 "subdocumento" => "crp" "cita" => "Actas Dermosifiliogr. 2016;107:e19-22" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 642 "formatos" => array:3 [ "EPUB" => 36 "HTML" => 440 "PDF" => 166 ] ] "Traduccion" => array:1 [ "es" => array:19 [ "pii" => "S0001731015004883" "issn" => "00017310" "doi" => "10.1016/j.ad.2015.05.019" "estado" => "S300" "fechaPublicacion" => "2016-05-01" "aid" => "1292" "copyright" => "Elsevier España, S.L.U. y AEDV" "documento" => "simple-article" "crossmark" => 1 "subdocumento" => "crp" "cita" => "Actas Dermosifiliogr. 2016;107:e19-22" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 276 "formatos" => array:3 [ "EPUB" => 4 "HTML" => 145 "PDF" => 127 ] ] "es" => array:13 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">E-Casos Clínicos</span>" "titulo" => "Ecografía cutánea en el sarcoma de Kaposi" "tienePdf" => "es" "tieneTextoCompleto" => "es" "tieneResumen" => array:2 [ 0 => "es" 1 => "en" ] "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "e19" "paginaFinal" => "e22" ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Skin Ultrasound in Kaposi Sarcoma" ] ] "contieneResumen" => array:2 [ "es" => true "en" => true ] "contieneTextoCompleto" => array:1 [ "es" => true ] "contienePdf" => array:1 [ "es" => true ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:7 [ "identificador" => "fig0005" "etiqueta" => "Figura 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 1427 "Ancho" => 3333 "Tamanyo" => 492978 ] ] "descripcion" => array:1 [ "es" => "<p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">A) Nódulo violáceo-rojizo localizado en el tobillo derecho. B) En la imagen ecográfica se aprecia una lesión sólida, hipoecoica, de estructura homogénea, de forma ovalada y bordes regulares y bien definidos localizada en la dermis papilar y reticular. El Doppler color mostró una intensa vascularización intralesional, más marcada en el polo inferior y en el modo espectral se observaba un flujo arterial bifásico.</p>" ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "R. Carrascosa, F. Alfageme, G. Roustán, M.D. Suarez" "autores" => array:4 [ 0 => array:2 [ "nombre" => "R." "apellidos" => "Carrascosa" ] 1 => array:2 [ "nombre" => "F." "apellidos" => "Alfageme" ] 2 => array:2 [ "nombre" => "G." "apellidos" => "Roustán" ] 3 => array:2 [ "nombre" => "M.D." "apellidos" => "Suarez" ] ] ] ] ] "idiomaDefecto" => "es" "Traduccion" => array:1 [ "en" => array:9 [ "pii" => "S1578219016300099" "doi" => "10.1016/j.adengl.2016.02.023" "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:1 [ "total" => 0 ] "idiomaDefecto" => "en" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219016300099?idApp=UINPBA000044" ] ] "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0001731015004883?idApp=UINPBA000044" "url" => "/00017310/0000010700000004/v1_201604280046/S0001731015004883/v1_201604280046/es/main.assets" ] ] "itemSiguiente" => array:19 [ "pii" => "S1578219016000603" "issn" => "15782190" "doi" => "10.1016/j.adengl.2016.02.004" "estado" => "S300" "fechaPublicacion" => "2016-05-01" "aid" => "1282" "copyright" => "AEDV" "documento" => "simple-article" "crossmark" => 1 "subdocumento" => "crp" "cita" => "Actas Dermosifiliogr. 2016;107:e23-6" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 661 "formatos" => array:3 [ "EPUB" => 44 "HTML" => 487 "PDF" => 130 ] ] "en" => array:13 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">e-Case Report</span>" "titulo" => "Axillary Silicone Granulomas in Patients With Melanoma" "tienePdf" => "en" "tieneTextoCompleto" => "en" "tieneResumen" => array:2 [ 0 => "en" 1 => "es" ] "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "e23" "paginaFinal" => "e26" ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Siliconomas axilares en pacientes con melanoma" ] ] "contieneResumen" => array:2 [ "en" => true "es" => true ] "contieneTextoCompleto" => array:1 [ "en" => true ] "contienePdf" => array:1 [ "en" => true ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:7 [ "identificador" => "fig0010" "etiqueta" => "Figure 2" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr2.jpeg" "Alto" => 733 "Ancho" => 1301 "Tamanyo" => 97369 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">Single-chamber subglandular breast implant. Arrow: Artifact produced by extravasated gel in the space between the fold of the outer shell of the implant and the fibrous capsule surrounding the implant, a finding associated with intracapsular rupture. Star: Reverberation artifact.</p>" ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "M.I. Fernández Canedo, N. Blázquez Sánchez, P. Valdés Solís, M. de Troya Martín" "autores" => array:4 [ 0 => array:2 [ "nombre" => "M.I." "apellidos" => "Fernández Canedo" ] 1 => array:2 [ "nombre" => "N." "apellidos" => "Blázquez Sánchez" ] 2 => array:2 [ "nombre" => "P." "apellidos" => "Valdés Solís" ] 3 => array:2 [ "nombre" => "M." "apellidos" => "de Troya Martín" ] ] ] ] ] "idiomaDefecto" => "en" "Traduccion" => array:1 [ "es" => array:9 [ "pii" => "S0001731015004408" "doi" => "10.1016/j.ad.2015.05.016" "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:1 [ "total" => 0 ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0001731015004408?idApp=UINPBA000044" ] ] "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219016000603?idApp=UINPBA000044" "url" => "/15782190/0000010700000004/v1_201604280043/S1578219016000603/v1_201604280043/en/main.assets" ] "itemAnterior" => array:19 [ "pii" => "S1578219016300087" "issn" => "15782190" "doi" => "10.1016/j.adengl.2016.02.022" "estado" => "S300" "fechaPublicacion" => "2016-05-01" "aid" => "1335" "copyright" => "AEDV" "documento" => "article" "crossmark" => 1 "subdocumento" => "fla" "cita" => "Actas Dermosifiliogr. 2016;107:329-36" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 847 "formatos" => array:3 [ "EPUB" => 40 "HTML" => 564 "PDF" => 243 ] ] "en" => array:13 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Original</span>" "titulo" => "Allergic Contact Dermatitis Due to Cosmetics: A Clinical and Epidemiological Study in a Tertiary Hospital" "tienePdf" => "en" "tieneTextoCompleto" => "en" "tieneResumen" => array:2 [ 0 => "en" 1 => "es" ] "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "329" "paginaFinal" => "336" ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Dermatitis alérgica de contacto a cosméticos, estudio clínico-epidemiológico en un hospital terciario" ] ] "contieneResumen" => array:2 [ "en" => true "es" => true ] "contieneTextoCompleto" => array:1 [ "en" => true ] "contienePdf" => array:1 [ "en" => true ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:7 [ "identificador" => "fig0025" "etiqueta" => "Figure 5" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr5.jpeg" "Alto" => 1741 "Ancho" => 2424 "Tamanyo" => 221645 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0050" class="elsevierStyleSimplePara elsevierViewall">Allergens causing ACD to cosmetics during the second period (2005-2013).</p>" ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "V. Zaragoza-Ninet, R. Blasco Encinas, J.J. Vilata-Corell, A. Pérez-Ferriols, C. Sierra-Talamantes, A. Esteve-Martínez, J. de la Cuadra-Oyanguren" "autores" => array:7 [ 0 => array:2 [ "nombre" => "V." "apellidos" => "Zaragoza-Ninet" ] 1 => array:2 [ "nombre" => "R." "apellidos" => "Blasco Encinas" ] 2 => array:2 [ "nombre" => "J.J." "apellidos" => "Vilata-Corell" ] 3 => array:2 [ "nombre" => "A." "apellidos" => "Pérez-Ferriols" ] 4 => array:2 [ "nombre" => "C." "apellidos" => "Sierra-Talamantes" ] 5 => array:2 [ "nombre" => "A." "apellidos" => "Esteve-Martínez" ] 6 => array:2 [ "nombre" => "J." "apellidos" => "de la Cuadra-Oyanguren" ] ] ] ] ] "idiomaDefecto" => "en" "Traduccion" => array:1 [ "es" => array:9 [ "pii" => "S0001731016000077" "doi" => "10.1016/j.ad.2015.12.007" "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:1 [ "total" => 0 ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0001731016000077?idApp=UINPBA000044" ] ] "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219016300087?idApp=UINPBA000044" "url" => "/15782190/0000010700000004/v1_201604280043/S1578219016300087/v1_201604280043/en/main.assets" ] "en" => array:20 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">E-Case Report</span>" "titulo" => "Skin Ultrasound in Kaposi Sarcoma" "tieneTextoCompleto" => true "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "e19" "paginaFinal" => "e22" ] ] "autores" => array:1 [ 0 => array:4 [ "autoresLista" => "R. Carrascosa, F. Alfageme, G. Roustán, M.D. Suarez" "autores" => array:4 [ 0 => array:4 [ "nombre" => "R." "apellidos" => "Carrascosa" "email" => array:1 [ 0 => "rachel170786@gmail.com" ] "referencia" => array:2 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] 1 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">*</span>" "identificador" => "cor0005" ] ] ] 1 => array:3 [ "nombre" => "F." "apellidos" => "Alfageme" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff0010" ] ] ] 2 => array:3 [ "nombre" => "G." "apellidos" => "Roustán" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff0010" ] ] ] 3 => array:3 [ "nombre" => "M.D." "apellidos" => "Suarez" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">c</span>" "identificador" => "aff0015" ] ] ] ] "afiliaciones" => array:3 [ 0 => array:3 [ "entidad" => "Servicio de Dermatología, Hospital Universitario La Princesa, Madrid, Spain" "etiqueta" => "a" "identificador" => "aff0005" ] 1 => array:3 [ "entidad" => "Servicio de Dermatología, Hospital Universitario Puerta de Hierro , Majadahonda, Madrid, Spain" "etiqueta" => "b" "identificador" => "aff0010" ] 2 => array:3 [ "entidad" => "Servicio de Anatomía Patológica, Hospital Universitario Puerta de Hierro, Majadahonda, Madrid, Spain" "etiqueta" => "c" "identificador" => "aff0015" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "⁎" "correspondencia" => "Corresponding author." ] ] ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Ecografía cutánea en el sarcoma de Kaposi" ] ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:7 [ "identificador" => "fig0015" "etiqueta" => "Figure 3" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr3.jpeg" "Alto" => 1362 "Ancho" => 1000 "Tamanyo" => 251928 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">A, Reddish-violaceous nodule on the dorsum of the right hand. B, Multiple reddish-violaceous papules coalescing to form plaques on the anterior surface of the legs. C, Ultrasound of the nodule revealed a solid, hypoechoic, homogeneous oval lesion with well-defined and regular edges in the papillary and reticular dermis. Color Doppler revealed mild intralesional vascularization in the inferior pole. D, Ultrasound examination of the plaque revealed a solid, hypoechoic, heterogeneous lesion with irregular, acicular edges in the papillary dermis. No intralesional vascularization was observed in color Doppler.</p>" ] ] ] "textoCompleto" => "<span class="elsevierStyleSections"><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0025">Introduction</span><p id="par0005" class="elsevierStylePara elsevierViewall">Kaposi sarcoma (KS) is a tumor that arises in the vascular endothelium and mainly affects the skin and mucosae, although it can spread to the lymph nodes and even to internal organs.<a class="elsevierStyleCrossRefs" href="#bib0080"><span class="elsevierStyleSup">1,2</span></a> Human herpesvirus 8 (HHV-8) is considered the etiologic agent of KS.<a class="elsevierStyleCrossRef" href="#bib0090"><span class="elsevierStyleSup">3</span></a> The 4 clinical variants of KS are classic KS (CKS), iatrogenic KS (IKS), endemic (African) KS, and KS associated with AIDS (AIDS-KS).<a class="elsevierStyleCrossRefs" href="#bib0080"><span class="elsevierStyleSup">1,2,4</span></a> The suspected diagnosis is based on the presence of macules, plaques, and/or nodules, which may be violaceous or reddish and asymptomatic, although up to 10 different clinical forms have been reported.<a class="elsevierStyleCrossRef" href="#bib0085"><span class="elsevierStyleSup">2</span></a> The lesions have a characteristic distribution on the lower leg, except in the case of AIDS-KS, in which the lesions mainly affect the face and trunk.<a class="elsevierStyleCrossRef" href="#bib0095"><span class="elsevierStyleSup">4</span></a> Diagnosis is confirmed by skin biopsy, which typically reveals proliferation of irregular cleft-shaped vessels and spindle-shaped cells, with no significant histologic differences between the clinical variants.<a class="elsevierStyleCrossRefs" href="#bib0080"><span class="elsevierStyleSup">1,4</span></a></p><p id="par0010" class="elsevierStylePara elsevierViewall">Use of ultrasound was recently implemented in several skin diseases, such as inflammatory dermatoses and benign and malignant tumors, as well as in cosmetic dermatology.<a class="elsevierStyleCrossRefs" href="#bib0100"><span class="elsevierStyleSup">5–11</span></a></p><p id="par0015" class="elsevierStylePara elsevierViewall">We report 3 cases of KS in which skin lesions were evaluated using B-mode and color Doppler ultrasound. Here, we aim to establish a correlation between ultrasound findings and the clinical and histologic characteristics of KS skin lesions and to describe the usefulness of both types of ultrasound in this disease.</p></span><span id="sec0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0030">Case Descriptions</span><span id="sec0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0035">Patient 1</span><p id="par0020" class="elsevierStylePara elsevierViewall">The patient was an 80-year-old woman who consulted for an asymptomatic nodule that recently appeared on her right ankle. She had developed a similar lesion on the same leg 5 years previously. The lesion was confirmed both clinically and histologically as CKS, and the result of the extension study was negative. The lesion was treated with surgery. The physical examination revealed a reddish-violaceous nodular lesion on the internal surface of the right ankle (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>A). B-mode ultrasound revealed a solid hypoechoic, homogeneous, solid oval lesion with regular, well-defined edges. The lesion affected the papillary and reticular dermis. Color Doppler revealed intense intralesional vascularization that was more marked on the inferior pole. Spectral analysis showed biphasic arterial flow (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>B). KS was confirmed by histology, and the lesion was removed. The result of a second extension study was negative. The patient continues to be followed, with no signs of new lesions.</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia></span><span id="sec0020" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0040">Patient 2</span><p id="par0025" class="elsevierStylePara elsevierViewall">The patient was a 42-year-old man diagnosed with pulmonary fibrosis who had received a lung transplant 5 years previously followed by immunosuppressive treatment. He consulted for 2 localized asymptomatic plaques that had appeared on his left leg 2 months earlier. Physical examination revealed 2 reddish-violaceous plaques on the anterior surface of the thigh and left knee (<a class="elsevierStyleCrossRef" href="#fig0010">Fig. 2</a>A). The B-mode ultrasound examination revealed a solid, hypoechoic, and heterogeneous lesion with irregular, acicular edges that reached the papillary dermis. Color Doppler ultrasound did not reveal intralesional vascularization (<a class="elsevierStyleCrossRef" href="#fig0010">Fig. 2</a>B). The skin biopsy confirmed the diagnosis of IKS, and the results of serology testing were positive for HHV-8 and cytomegalovirus. The results of the extension study were negative. The lesions improved when immunosuppressive treatment was modified.</p><elsevierMultimedia ident="fig0010"></elsevierMultimedia></span><span id="sec0025" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0045">Patient 3</span><p id="par0030" class="elsevierStylePara elsevierViewall">The patient was a 67-year-old man who had received a heart transplant 7 years earlier. Surgery was followed by immunosuppressive treatment. He consulted for asymptomatic nodules and papulae that had appeared 3 months previously on his legs, hands, and palate. The physical examination revealed a reddish papule on the hard palate, a reddish-violaceous nodule on the dorsum of the right hand, and multiple reddish-violaceous papules grouped in plaques on the anterior surface of the legs (<a class="elsevierStyleCrossRef" href="#fig0015">Fig. 3</a>, A and B). B-mode ultrasound of 1 of the plaques on the legs revealed a solid hypoechoic, heterogeneous lesion with irregular acicular edges affecting the papillary dermis. Examination of the nodule on the hand using the same technique revealed a solid, hypoechoic, homogeneous oval or round lesion with irregular, well-defined edges affecting the papillary and reticular dermis. Color Doppler revealed no intralesional vascularization in the plaque-like lesion, although in the case of the nodule, slight vascularization was visible at the inferior pole (<a class="elsevierStyleCrossRef" href="#fig0015">Fig. 3</a>, C and D). Skin biopsy confirmed the diagnosis of IKS. The results of the extension study were negative, and the lesions improved when immunosuppressive therapy was modified.</p><elsevierMultimedia ident="fig0015"></elsevierMultimedia></span></span><span id="sec0030" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0050">Discussion</span><p id="par0035" class="elsevierStylePara elsevierViewall">In the cases of KS we report, the pattern revealed by B-mode ultrasound was solid and hypoechoic, and the lesions were located in the dermis. Nodules were more homogeneous, with regular, well-defined outlines, whereas plaques were less homogeneous with irregular edges, acicular morphology, and less well-defined outlines. A review of the literature reveals few studies that use cutaneous ultrasound to describe the structural characteristics of KS skin lesions; in addition, the results of these studies are contradictory. In 1993, Bogner et al.<a class="elsevierStyleCrossRef" href="#bib0135"><span class="elsevierStyleSup">12</span></a> described KS skin lesions as hypoechoic, with a homogeneous structure and well-defined outlines. In contrast, Cammarota<a class="elsevierStyleCrossRef" href="#bib0140"><span class="elsevierStyleSup">13</span></a> reported the KS ultrasound pattern to consist of a solid, nonhomogeneous nodule with a poorly defined outline. More recently, in 2011, Solivetti et al.,<a class="elsevierStyleCrossRef" href="#bib0145"><span class="elsevierStyleSup">14</span></a> who used higher-frequency probes, analyzed the ultrasound characteristics of KS skin lesions (confirmed by histology) in 24 patients, from each of whom a single skin lesion (both plaques and nodules) was selected according to its size (0.4<span class="elsevierStyleHsp" style=""></span>cm-2<span class="elsevierStyleHsp" style=""></span>cm). Their ultrasound pattern corresponded to hypoechoic lesions with well-defined (and frequently multilobulated) outlines located between the epidermis and dermis and, in some cases, in the subcutaneous layer. Most of the lesions had a homogeneous structure, which was more homogeneous in CKS lesions than in AIDS-KS lesions. However, the authors admit that this finding could be attributed to the small size of the lesions studied (all <2<span class="elsevierStyleHsp" style=""></span>cm) and the possibility that the largest lesions could have a more heterogeneous structure owing to intratumoral degeneration, necrosis, and/or fibrosis.</p><p id="par0040" class="elsevierStylePara elsevierViewall">As for color Doppler, we observed intralesional vascularization that was more marked at the lower pole in lesions clinically defined as nodules and markedly diminished or absent vascularization in lesions that were clinically defined as plaques. Only 1 study in the literature used color Doppler to describe the vascular characteristics of KS skin lesions.<a class="elsevierStyleCrossRef" href="#bib0145"><span class="elsevierStyleSup">14</span></a> The authors found that the skin lesions of CKS and those of AIDS-KS differed and that intralesional vascularization was absent in most cases of CKS and often present in those of AIDS-KS. They postulated that the intralesional vascularization found in the latter could be associated with the formation of new vessels induced by the human immunodeficiency virus<a class="elsevierStyleCrossRef" href="#bib0150"><span class="elsevierStyleSup">15</span></a>; however, in CKS with intralesional vascularization, this ultrasound finding could be associated with a more aggressive clinical picture or higher HHV-8 load.<a class="elsevierStyleCrossRef" href="#bib0145"><span class="elsevierStyleSup">14</span></a></p><p id="par0045" class="elsevierStylePara elsevierViewall">In conclusion, cutaneous ultrasound (B-mode and color Doppler) could be useful as a complementary test in the study of skin lesions in KS. The technique could provide us with more information on the structural and vascular characteristics of the lesions.</p></span><span id="sec0035" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0055">Conflicts of Interest</span><p id="par0050" class="elsevierStylePara elsevierViewall">The authors declare that they have no conflicts of interest.</p></span></span>" "textoCompletoSecciones" => array:1 [ "secciones" => array:9 [ 0 => array:3 [ "identificador" => "xres631837" "titulo" => "Abstract" "secciones" => array:1 [ 0 => array:1 [ "identificador" => "abst0005" ] ] ] 1 => array:2 [ "identificador" => "xpalclavsec644633" "titulo" => "Keywords" ] 2 => array:3 [ "identificador" => "xres631838" "titulo" => "Resumen" "secciones" => array:1 [ 0 => array:1 [ "identificador" => "abst0010" ] ] ] 3 => array:2 [ "identificador" => "xpalclavsec644632" "titulo" => "Palabras clave" ] 4 => array:2 [ "identificador" => "sec0005" "titulo" => "Introduction" ] 5 => array:3 [ "identificador" => "sec0010" "titulo" => "Case Descriptions" "secciones" => array:3 [ 0 => array:2 [ "identificador" => "sec0015" "titulo" => "Patient 1" ] 1 => array:2 [ "identificador" => "sec0020" "titulo" => "Patient 2" ] 2 => array:2 [ "identificador" => "sec0025" "titulo" => "Patient 3" ] ] ] 6 => array:2 [ "identificador" => "sec0030" "titulo" => "Discussion" ] 7 => array:2 [ "identificador" => "sec0035" "titulo" => "Conflicts of Interest" ] 8 => array:1 [ "titulo" => "References" ] ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "2015-03-10" "fechaAceptado" => "2015-05-26" "PalabrasClave" => array:2 [ "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Keywords" "identificador" => "xpalclavsec644633" "palabras" => array:4 [ 0 => "Kaposi sarcoma" 1 => "Ultrasound" 2 => "Doppler" 3 => "Diagnosis" ] ] ] "es" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palabras clave" "identificador" => "xpalclavsec644632" "palabras" => array:4 [ 0 => "Sarcoma de Kaposi" 1 => "Ultrasonidos" 2 => "Doppler" 3 => "Diagnóstico" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "en" => array:2 [ "titulo" => "Abstract" "resumen" => "<span id="abst0005" class="elsevierStyleSection elsevierViewall"><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">The use of ultrasound imaging has recently been increasing in numerous dermatologic diseases. This noninvasive technique provides additional details on the structure and vascularization of skin lesions. Kaposi sarcoma is a vascular tumor that typically arises in the skin and mucosas. It can spread to lymph nodes and internal organs. We performed B-mode and color Doppler ultrasound studies in 3 patients with a clinical diagnosis of Kaposi sarcoma confirmed by histological examination. We found differences in the ultrasound pattern between nodular and plaque lesions, in both B-mode and color Doppler. We believe that skin ultrasound imaging could be a useful technique for studying cutaneous Kaposi sarcoma, providing additional information on the structural and vascular characteristics of the lesion.</p></span>" ] "es" => array:2 [ "titulo" => "Resumen" "resumen" => "<span id="abst0010" class="elsevierStyleSection elsevierViewall"><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Recientemente ha aumentado el uso de la ecografía cutánea en múltiples enfermedades dermatológicas. Se trata de una técnica no invasiva, que nos proporciona más detalles acerca de la estructura y vascularización de las lesiones cutáneas. El sarcoma de Kaposi es un tumor vascular, que se localiza principalmente en la piel y las mucosas, pudiendo afectar los ganglios linfáticos y los órganos internos. Presentamos 3 pacientes con diagnóstico de sarcoma de Kaposi, sospechado clínicamente, y confirmado histológicamente, a los cuales realizamos exploración ecográfica en modo B y modo Doppler color. Encontramos diferencias en el patrón ecográfico, tanto en modo B como en modo Doppler color, entre las lesiones que clínicamente correspondían a nódulos frente a las que eran placas. Consideramos que la ecografía cutánea podría ser útil como prueba complementaria, en el estudio de las lesiones cutáneas del sarcoma de Kaposi, proporcionándonos más información acerca de sus características estructurales y vasculares.</p></span>" ] ] "NotaPie" => array:1 [ 0 => array:2 [ "etiqueta" => "☆" "nota" => "<p class="elsevierStyleNotepara" id="npar0005">Please cite this article as: Carrascosa R, Alfageme F, Roustán G, Suarez MD. Ecografía cutánea en el sarcoma de Kaposi. Actas Dermosifiliogr. 2016;107:e19–e22.</p>" ] ] "multimedia" => array:3 [ 0 => array:7 [ "identificador" => "fig0005" "etiqueta" => "Figure 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 857 "Ancho" => 2000 "Tamanyo" => 250166 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">A, Reddish-violaceous nodule on the right ankle. B, The ultrasound lesion shows a solid, hypoechoic, homogeneous oval lesion with regular, well-defined edges in the papillary and reticular dermis. Color Doppler shows intense intralesional vascularization that is more marked in the inferior pole. Biphasic arterial flow is observed in spectral mode.</p>" ] ] 1 => array:7 [ "identificador" => "fig0010" "etiqueta" => "Figure 2" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr2.jpeg" "Alto" => 773 "Ancho" => 2000 "Tamanyo" => 236476 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">A, Reddish-violaceous plaque on the anterior surface of the left thigh. B, The ultrasound examination revealed a solid, hypoechoic, heterogeneous lesion with irregular, acicular edges in the papillary dermis. Color Doppler did not reveal intralesional vascularization.</p>" ] ] 2 => array:7 [ "identificador" => "fig0015" "etiqueta" => "Figure 3" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr3.jpeg" "Alto" => 1362 "Ancho" => 1000 "Tamanyo" => 251928 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">A, Reddish-violaceous nodule on the dorsum of the right hand. B, Multiple reddish-violaceous papules coalescing to form plaques on the anterior surface of the legs. C, Ultrasound of the nodule revealed a solid, hypoechoic, homogeneous oval lesion with well-defined and regular edges in the papillary and reticular dermis. Color Doppler revealed mild intralesional vascularization in the inferior pole. D, Ultrasound examination of the plaque revealed a solid, hypoechoic, heterogeneous lesion with irregular, acicular edges in the papillary dermis. No intralesional vascularization was observed in color Doppler.</p>" ] ] ] "bibliografia" => array:2 [ "titulo" => "References" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:15 [ 0 => array:3 [ "identificador" => "bib0080" "etiqueta" => "1" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Kaposi sarcoma: Review and medical management update" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "M. Fatahzadeh" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/j.tripleo.2011.05.011" "Revista" => array:6 [ "tituloSerie" => "Oral Surg Oral Med Oral Pathol Oral Radiol" "fecha" => "2012" "volumen" => "113" "paginaInicial" => "2" "paginaFinal" => "16" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/22677687" "web" => "Medline" ] ] ] ] ] ] ] ] 1 => array:3 [ "identificador" => "bib0085" "etiqueta" => "2" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Kaposi's sarcoma: An update" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "R.A. Schwartz" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1002/jso.20090" "Revista" => array:6 [ "tituloSerie" => "J Surg Oncol" "fecha" => "2004" "volumen" => "87" "paginaInicial" => "146" "paginaFinal" => "151" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15334644" "web" => "Medline" ] ] ] ] ] ] ] ] 2 => array:3 [ "identificador" => "bib0090" "etiqueta" => "3" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Human herpesvirus type 8 variants circulating in Europe, Africa and North America in classic, endemic and epidemic Kaposi's sarcoma lesions during pre-AIDS and AIDS era" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "M.L. Tornesello" 1 => "B. Biryahwaho" 2 => "R. Downing" 3 => "A. Hatzakis" 4 => "E. Alessi" 5 => "M. Cusini" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/j.virol.2009.12.005" "Revista" => array:6 [ "tituloSerie" => "Virology" "fecha" => "2010" "volumen" => "398" "paginaInicial" => "280" "paginaFinal" => "289" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/20079510" "web" => "Medline" ] ] ] ] ] ] ] ] 3 => array:3 [ "identificador" => "bib0095" "etiqueta" => "4" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Cutaneous vascular proliferations. Part III. Malignant neoplasm, other cutaneous neoplasms with significant vascular component, and disorders erroneously considered as vascular neoplasms" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "L. Requena" 1 => "O.P. Sanguenza" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "J Am Acad Dermatol" "fecha" => "1998" "volumen" => "38" "paginaInicial" => "143" "paginaFinal" => "175" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9486670" "web" => "Medline" ] ] ] ] ] ] ] ] 4 => array:3 [ "identificador" => "bib0100" "etiqueta" => "5" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Manual de ecografía cutánea" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "F. Alfageme" 1 => "E. Cerezo" 2 => "C. Villegas" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Libro" => array:3 [ "fecha" => "2013" "editorial" => "Createspace Independent Platform Publisher" "editorialLocalizacion" => "Charleston" ] ] ] ] ] ] 5 => array:3 [ "identificador" => "bib0105" "etiqueta" => "6" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Common applications of dermatologic sonography" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "X. Wortsman" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:7 [ "tituloSerie" => "J Ultrasound Med" "fecha" => "2012" "volumen" => "31" "paginaInicial" => "97" "paginaFinal" => "111" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/22215775" "web" => "Medline" ] ] "itemHostRev" => array:3 [ "pii" => "S000293940900453X" "estado" => "S300" "issn" => "00029394" ] ] ] ] ] ] ] 6 => array:3 [ "identificador" => "bib0110" "etiqueta" => "7" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Tumores glómicos digitales y extradigitales. Utilidad de la ecografía cutánea" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "M.E. Gómez-Sánchez" 1 => "F. Alfageme-Roldán" 2 => "G. Roustán-Gullón" 3 => "M.A. Segurado-Rodríguez" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/j.ad.2013.06.002" "Revista" => array:6 [ "tituloSerie" => "Actas Dermosifiliogr" "fecha" => "2014" "volumen" => "105" "paginaInicial" => "45" "paginaFinal" => "49" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/23938072" "web" => "Medline" ] ] ] ] ] ] ] ] 7 => array:3 [ "identificador" => "bib0115" "etiqueta" => "8" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Evaluación de la ecografía cutánea de 15 Mhz en la estimación preoperatoria del espesor tumoral en el melanoma maligno" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "I. Fernández Canedo" 1 => "M. de Troya Martín" 2 => "R. Fúnez Liébana" 3 => "F. Rivas Ruiz" 4 => "G. Blanco Eguren" 5 => "N. Blázquez Sánchez" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/j.ad.2012.06.007" "Revista" => array:6 [ "tituloSerie" => "Actas Dermosifiliogr" "fecha" => "2013" "volumen" => "104" "paginaInicial" => "227" "paginaFinal" => "231" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/22938997" "web" => "Medline" ] ] ] ] ] ] ] ] 8 => array:3 [ "identificador" => "bib0120" "etiqueta" => "9" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "¿Es la ecografía cutánea de alta frecuencia una alternativa en el diagnóstico y manejo del carcinoma basocelular" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "C. Hernández" 1 => "J. del Boz" 2 => "M. de Troya" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/j.ad.2013.09.004" "Revista" => array:6 [ "tituloSerie" => "Actas Dermosifiliogr" "fecha" => "2014" "volumen" => "105" "paginaInicial" => "107" "paginaFinal" => "111" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/24168914" "web" => "Medline" ] ] ] ] ] ] ] ] 9 => array:3 [ "identificador" => "bib0125" "etiqueta" => "10" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Ecografía cutánea" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "F. Alfageme" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/j.ad.2014.03.007" "Revista" => array:6 [ "tituloSerie" => "Actas Dermosifiliogr" "fecha" => "2014" "volumen" => "105" "paginaInicial" => "887" "paginaFinal" => "890" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/24997744" "web" => "Medline" ] ] ] ] ] ] ] ] 10 => array:3 [ "identificador" => "bib0130" "etiqueta" => "11" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The use of ultrasound imaging in dermatology" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "B. Echeverría-García" 1 => "J. Borbujo" 2 => "F. Alfageme" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/j.ad.2014.03.007" "Revista" => array:6 [ "tituloSerie" => "Actas Dermosifiliogr" "fecha" => "2014" "volumen" => "105" "paginaInicial" => "887" "paginaFinal" => "890" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/24997744" "web" => "Medline" ] ] ] ] ] ] ] ] 11 => array:3 [ "identificador" => "bib0135" "etiqueta" => "12" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Ultrasound as a tool to evaluate remission of cutaneous Kaposi's sarcoma" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "J.R. Bogner" 1 => "C. Zietz" 2 => "M. Held" 3 => "S. Spatling" 4 => "P. Sandor" 5 => "U. Kronawitter" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "J Acquir Inmune Defic Syndr" "fecha" => "1993" "volumen" => "6" "paginaInicial" => "530" "paginaFinal" => "531" "itemHostRev" => array:3 [ "pii" => "S0161642011008840" "estado" => "S300" "issn" => "01616420" ] ] ] ] ] ] ] 12 => array:3 [ "identificador" => "bib0140" "etiqueta" => "13" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Ecografía in Dermatologia" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "T. Cammarota" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Libro" => array:3 [ "fecha" => "1998" "editorial" => "Poletto Editore" "editorialLocalizacion" => "Milano" ] ] ] ] ] ] 13 => array:3 [ "identificador" => "bib0145" "etiqueta" => "14" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "AIDS-Kaposi Sarcoma and Classic Kaposi Sarcoma: Are different ultrasound patterns related to different variants?" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "F.M. Solivetti" 1 => "F. Elia" 2 => "A. Latini" 3 => "C. Cota" 4 => "P. Cordiali-Fei" 5 => "A. di Carlo" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1186/1756-9966-30-40" "Revista" => array:5 [ "tituloSerie" => "J Exp Clin Cancer Res" "fecha" => "2011" "volumen" => "30" "paginaInicial" => "40" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/21489270" "web" => "Medline" ] ] ] ] ] ] ] ] 14 => array:3 [ "identificador" => "bib0150" "etiqueta" => "15" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Angiogenic effects of extracellular human immunodeficiency virus type 1 Tat protein and its role in the pathogenesis of AIDS-associated Kaposi's Sarcoma" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "G. Barillari" 1 => "B. Ensoli" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Clin Microbiol Rev" "fecha" => "2002" "volumen" => "15" "paginaInicial" => "310" "paginaFinal" => "326" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11932235" "web" => "Medline" ] ] ] ] ] ] ] ] ] ] ] ] ] "idiomaDefecto" => "en" "url" => "/15782190/0000010700000004/v1_201604280043/S1578219016300099/v1_201604280043/en/main.assets" "Apartado" => array:4 [ "identificador" => "34944" "tipo" => "SECCION" "en" => array:2 [ "titulo" => "e- Case Report" "idiomaDefecto" => true ] "idiomaDefecto" => "en" ] "PDF" => "https://static.elsevier.es/multimedia/15782190/0000010700000004/v1_201604280043/S1578219016300099/v1_201604280043/en/main.pdf?idApp=UINPBA000044&text.app=https://actasdermo.org/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219016300099?idApp=UINPBA000044" ]
año/Mes | Html | Total | |
---|---|---|---|
2024 Noviembre | 4 | 2 | 6 |
2024 Octubre | 145 | 40 | 185 |
2024 Septiembre | 139 | 22 | 161 |
2024 Agosto | 203 | 66 | 269 |
2024 Julio | 233 | 38 | 271 |
2024 Junio | 190 | 28 | 218 |
2024 Mayo | 134 | 30 | 164 |
2024 Abril | 117 | 24 | 141 |
2024 Marzo | 114 | 36 | 150 |
2024 Febrero | 131 | 33 | 164 |
2024 Enero | 101 | 39 | 140 |
2023 Diciembre | 107 | 17 | 124 |
2023 Noviembre | 211 | 22 | 233 |
2023 Octubre | 176 | 23 | 199 |
2023 Septiembre | 108 | 27 | 135 |
2023 Agosto | 86 | 16 | 102 |
2023 Julio | 106 | 45 | 151 |
2023 Junio | 78 | 19 | 97 |
2023 Mayo | 95 | 22 | 117 |
2023 Abril | 99 | 20 | 119 |
2023 Marzo | 77 | 38 | 115 |
2023 Febrero | 81 | 35 | 116 |
2023 Enero | 55 | 22 | 77 |
2022 Diciembre | 66 | 43 | 109 |
2022 Noviembre | 69 | 34 | 103 |
2022 Octubre | 48 | 22 | 70 |
2022 Septiembre | 42 | 24 | 66 |
2022 Agosto | 42 | 35 | 77 |
2022 Julio | 40 | 33 | 73 |
2022 Junio | 37 | 19 | 56 |
2022 Mayo | 111 | 38 | 149 |
2022 Abril | 158 | 26 | 184 |
2022 Marzo | 173 | 37 | 210 |
2022 Febrero | 163 | 19 | 182 |
2022 Enero | 216 | 39 | 255 |
2021 Diciembre | 107 | 38 | 145 |
2021 Noviembre | 107 | 48 | 155 |
2021 Octubre | 106 | 55 | 161 |
2021 Septiembre | 145 | 48 | 193 |
2021 Agosto | 144 | 23 | 167 |
2021 Julio | 141 | 30 | 171 |
2021 Junio | 148 | 26 | 174 |
2021 Mayo | 87 | 51 | 138 |
2021 Abril | 131 | 54 | 185 |
2021 Marzo | 76 | 24 | 100 |
2021 Febrero | 71 | 41 | 112 |
2021 Enero | 66 | 30 | 96 |
2020 Diciembre | 39 | 16 | 55 |
2020 Noviembre | 32 | 31 | 63 |
2020 Octubre | 18 | 15 | 33 |
2020 Septiembre | 37 | 15 | 52 |
2020 Agosto | 33 | 13 | 46 |
2020 Julio | 20 | 14 | 34 |
2020 Junio | 37 | 33 | 70 |
2020 Mayo | 31 | 17 | 48 |
2020 Abril | 37 | 26 | 63 |
2020 Marzo | 31 | 15 | 46 |
2020 Febrero | 5 | 0 | 5 |
2019 Diciembre | 4 | 0 | 4 |
2019 Septiembre | 4 | 0 | 4 |
2019 Junio | 2 | 0 | 2 |
2019 Abril | 0 | 2 | 2 |
2019 Marzo | 2 | 6 | 8 |
2019 Enero | 2 | 0 | 2 |
2018 Noviembre | 1 | 0 | 1 |
2018 Octubre | 2 | 0 | 2 |
2018 Septiembre | 4 | 0 | 4 |
2018 Febrero | 28 | 7 | 35 |
2018 Enero | 38 | 6 | 44 |
2017 Diciembre | 42 | 6 | 48 |
2017 Noviembre | 29 | 7 | 36 |
2017 Octubre | 23 | 5 | 28 |
2017 Septiembre | 29 | 5 | 34 |
2017 Agosto | 32 | 7 | 39 |
2017 Julio | 19 | 10 | 29 |
2017 Junio | 31 | 5 | 36 |
2017 Mayo | 20 | 3 | 23 |
2017 Abril | 11 | 12 | 23 |
2017 Marzo | 24 | 13 | 37 |
2017 Febrero | 11 | 9 | 20 |
2017 Enero | 15 | 5 | 20 |
2016 Diciembre | 29 | 16 | 45 |
2016 Noviembre | 21 | 20 | 41 |
2016 Octubre | 13 | 18 | 31 |
2016 Julio | 2 | 3 | 5 |
2016 Mayo | 0 | 1 | 1 |