Images in Dermatology
Pruritic, Indurated Lesions on a Man's Forearms
Paciente con lesiones de pruriginosas e induras en antebrazos
K.H. Kima,d,
, J. Aneiros-Fernándezb, A. Buendía-Eismanc, S. Arias-Santiagod
Autor para correspondencia
a Department of Dermatology, University of Arkansas for Medical Sciences, Little Rock, AR, USA
b Department of Pathology, Virgen de las Nieves University Hospital, Granada, Spain
c Department of Dermatology, School of Medicine, Granada, Spain
d Department of Dermatology, Virgen de las Nieves University Hospital, Granada, Spain
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His medical history included no medications or exposures associated with his skin condition. He had been previously treated with oral amoxicillin, with no response.</p><p id="par0010" class="elsevierStylePara elsevierViewall">Physical examination revealed whitish-gray indurated plaques with surrounding erythema on the forearms (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>A). Laboratory tests including a complete blood count (no peripheral eosinophilia), serum electrolyte analysis, and bacterial and fungal cultures were negative. Skin biopsy showed spongiosis with subepidermal edema (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>B), perivascular eosinophilic infiltrate (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>C), diffuse interstitial inflammatory infiltrate with eosinophils and flame figures (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>D), and no evidence of vasculitis or foreign material.</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><p id="par0015" class="elsevierStylePara elsevierViewall">Based on the clinical and histological findings, a diagnosis of Wells syndrome (eosinophilic cellulitis) was established. The patient began treatment with systemic steroids (1<span class="elsevierStyleHsp" style=""></span>mg/kg/d), which resulted in resolution of the lesions within 4 weeks. Subsequently, the dose of steroids was gradually reduced, and completely discontinued after 1 month.</p><p id="par0020" class="elsevierStylePara elsevierViewall">While its initial clinical presentation can resemble that of cellulitis and several types of dermatitis, eosinophilic cellulitis can be distinguished from other dermatoses by its histological features (edema and dermal inflammatory infiltrate with eosinophils and flame figures) and the presence of whitish-gray, morphea-like, indurated plaques.</p></span>" "pdfFichero" => "main.pdf" "tienePdf" => true "multimedia" => array:1 [ 0 => array:6 [ "identificador" => "fig0005" "etiqueta" => "Figure 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 1030 "Ancho" => 1301 "Tamanyo" => 383730 ] ] ] ] ] "idiomaDefecto" => "en" "url" => "/15782190/0000010700000002/v2_201703220318/S1578219016000408/v2_201703220318/en/main.assets" "Apartado" => array:4 [ "identificador" => "41141" "tipo" => "SECCION" "en" => array:2 [ "titulo" => "Images in Dermatology" "idiomaDefecto" => true ] "idiomaDefecto" => "en" ] "PDF" => "https://static.elsevier.es/multimedia/15782190/0000010700000002/v2_201703220318/S1578219016000408/v2_201703220318/en/main.pdf?idApp=UINPBA000044&text.app=https://actasdermo.org/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219016000408?idApp=UINPBA000044" ]
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