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array:23 [ "pii" => "S1578219015002784" "issn" => "15782190" "doi" => "10.1016/j.adengl.2015.10.016" "estado" => "S300" "fechaPublicacion" => "2015-12-01" "aid" => "1242" "copyright" => "Elsevier España, S.L.U. and AEDV" "copyrightAnyo" => "2015" "documento" => "simple-article" "crossmark" => 1 "subdocumento" => "cor" "cita" => "Actas Dermosifiliogr. 2015;106:860" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 725 "formatos" => array:3 [ "EPUB" => 51 "HTML" => 458 "PDF" => 216 ] ] "Traduccion" => array:1 [ "es" => array:19 [ "pii" => "S0001731015003464" "issn" => "00017310" "doi" => "10.1016/j.ad.2015.08.003" "estado" => "S300" "fechaPublicacion" => "2015-12-01" "aid" => "1242" "copyright" => "Elsevier España, S.L.U. y AEDV" "documento" => "simple-article" "crossmark" => 1 "subdocumento" => "cor" "cita" => "Actas Dermosifiliogr. 2015;106:860" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 442 "formatos" => array:3 [ "EPUB" => 4 "HTML" => 251 "PDF" => 187 ] ] "es" => array:10 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Cartas al Director</span>" "titulo" => "Comentario a: “Hidrosadenitis supurativa: nuevas oportunidades para una enfermedad dermatológica huérfana”" "tienePdf" => "es" "tieneTextoCompleto" => "es" "paginas" => array:1 [ 0 => array:1 [ "paginaInicial" => "860" ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Comment on “Hidradenitis Suppurativa: New Opportunities for an Orphan Skin Disease”" ] ] "contieneTextoCompleto" => array:1 [ "es" => true ] "contienePdf" => array:1 [ "es" => true ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "B. González-Sixto, M.Á. Rodríguez-Prieto" "autores" => array:2 [ 0 => array:2 [ "nombre" => "B." "apellidos" => "González-Sixto" ] 1 => array:2 [ "nombre" => "M.Á." "apellidos" => "Rodríguez-Prieto" ] ] ] ] ] "idiomaDefecto" => "es" "Traduccion" => array:1 [ "en" => array:9 [ "pii" => "S1578219015002784" "doi" => "10.1016/j.adengl.2015.10.016" "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:1 [ "total" => 0 ] "idiomaDefecto" => "en" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219015002784?idApp=UINPBA000044" ] ] "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0001731015003464?idApp=UINPBA000044" "url" => "/00017310/0000010600000010/v1_201512080105/S0001731015003464/v1_201512080105/es/main.assets" ] ] "itemAnterior" => array:19 [ "pii" => "S1578219015002711" "issn" => "15782190" "doi" => "10.1016/j.adengl.2015.10.010" "estado" => "S300" "fechaPublicacion" => "2015-12-01" "aid" => "1229" "copyright" => "Elsevier España, S.L.U. and AEDV" "documento" => "simple-article" "crossmark" => 1 "subdocumento" => "crp" "cita" => "Actas Dermosifiliogr. 2015;106:857-9" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 1863 "formatos" => array:3 [ "EPUB" => 48 "HTML" => 915 "PDF" => 900 ] ] "en" => array:11 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Case and Research Letters</span>" "titulo" => "Dermoscopic Features of Lichen Planus Pigmentosus-Inversus" "tienePdf" => "en" "tieneTextoCompleto" => "en" "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "857" "paginaFinal" => "859" ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Dermatoscopia del liquen plano pigmentado inverso" ] ] "contieneTextoCompleto" => array:1 [ "en" => true ] "contienePdf" => array:1 [ "en" => true ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:7 [ "identificador" => "fig0005" "etiqueta" => "Figure 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 600 "Ancho" => 1751 "Tamanyo" => 187803 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">A, Hyperpigmented plaques with a flat surface in the right axilla. B, Dermoscopic image of hyperpigmented plaque in the right axilla. A homogeneous white-bluish pattern (yellow circle) is observed with presence of blue-grayish globules and dots and red lines, predominantly in the periphery (red circle). DermLite II Pro-HR (10<span class="elsevierStyleHsp" style=""></span>x).</p>" ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "A. Imbernón-Moya, M. Churruca-Grijelmo, M. Martínez-Pérez, A. Lobato-Berezo" "autores" => array:4 [ 0 => array:2 [ "nombre" => "A." "apellidos" => "Imbernón-Moya" ] 1 => array:2 [ "nombre" => "M." "apellidos" => "Churruca-Grijelmo" ] 2 => array:2 [ "nombre" => "M." "apellidos" => "Martínez-Pérez" ] 3 => array:2 [ "nombre" => "A." "apellidos" => "Lobato-Berezo" ] ] ] ] ] "idiomaDefecto" => "en" "Traduccion" => array:1 [ "es" => array:9 [ "pii" => "S0001731015003336" "doi" => "10.1016/j.ad.2015.06.007" "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:1 [ "total" => 0 ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0001731015003336?idApp=UINPBA000044" ] ] "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219015002711?idApp=UINPBA000044" "url" => "/15782190/0000010600000010/v1_201512060022/S1578219015002711/v1_201512060022/en/main.assets" ] "en" => array:12 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Letter to Editor</span>" "titulo" => "Comment on “Hidradenitis Suppurativa: New Opportunities for an Orphan Skin Disease”" "tieneTextoCompleto" => true "paginas" => array:1 [ 0 => array:1 [ "paginaInicial" => "860" ] ] "autores" => array:1 [ 0 => array:4 [ "autoresLista" => "B. González-Sixto, M.Á. Rodríguez-Prieto" "autores" => array:2 [ 0 => array:3 [ "nombre" => "B." "apellidos" => "González-Sixto" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] ] ] 1 => array:4 [ "nombre" => "M.Á." "apellidos" => "Rodríguez-Prieto" "email" => array:1 [ 0 => "manuelangelro@gmail.com" ] "referencia" => array:2 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff0010" ] 1 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">*</span>" "identificador" => "cor0005" ] ] ] ] "afiliaciones" => array:2 [ 0 => array:3 [ "entidad" => "Servicio Dermatología. Xestión Integrada Pontevedra-Salnés, Pontevedra, Spain" "etiqueta" => "a" "identificador" => "aff0005" ] 1 => array:3 [ "entidad" => "Servicio Dermatología - Complejo Asistencial Universitario de León, León, Spain" "etiqueta" => "b" "identificador" => "aff0010" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "⁎" "correspondencia" => "Corresponding author." ] ] ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Comentario a: “Hidrosadenitis supurativa: nuevas oportunidades para una enfermedad dermatológica huérfana”" ] ] "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall"><span class="elsevierStyleItalic">To the Editor:</span></p><p id="par0010" class="elsevierStylePara elsevierViewall">First we would like to congratulate Dr. Carrascosa and his colleagues for their article “Hidradenitis Suppurativa: New Opportunities for an Orphan Skin Disease“<a class="elsevierStyleCrossRef" href="#bib0020"><span class="elsevierStyleSup">1</span></a> on the subject of a disease which, as they indicate, occurs almost always in young patients and has a severely negative impact on the patient's quality of life.</p><p id="par0015" class="elsevierStylePara elsevierViewall">We agree with the opinion expressed in the article that the treatment options for these patients are, in many cases, limited or almost nonexistent. In our hospital we have treated and are currently treating these patients with intralesional photodynamic therapy, with good results.<a class="elsevierStyleCrossRefs" href="#bib0025"><span class="elsevierStyleSup">2,3</span></a></p><p id="par0020" class="elsevierStylePara elsevierViewall">In a recently published series, we reported the results obtained in 27 patients, as follows: complete response in 37%, good response in 41%, and partial response in 19%.<a class="elsevierStyleCrossRef" href="#bib0030"><span class="elsevierStyleSup">3</span></a> In that series, 18 patients underwent a single session of treatment, 7 patients required 2 sessions, and 3 sessions were needed in 1 case. Only 1 of the patients with complete response needed more than 1 session. Tolerance to treatment was good except for 1 patient, in whom treatment was discontinued due to pain. Doppler ultrasound was performed on all the patients before treatment to assess the length and depth of the lesions to be treated. We used the following treatment protocol: 1% 5-aminolevulinate injected at a dose of 0.2<span class="elsevierStyleHsp" style=""></span>mL/cm<span class="elsevierStyleSup">2</span>; after which, following incubation for 3<span class="elsevierStyleHsp" style=""></span>hours, the lesion was irradiated intratumorally with a laser beam of 630<span class="elsevierStyleHsp" style=""></span>nm (1<span class="elsevierStyleHsp" style=""></span>W/cm<span class="elsevierStyleSup">2</span>) applied for 3<span class="elsevierStyleHsp" style=""></span>minutes using a fiber-optic probe.<a class="elsevierStyleCrossRef" href="#bib0030"><span class="elsevierStyleSup">3</span></a></p><p id="par0025" class="elsevierStylePara elsevierViewall">Although the level of evidence provided by this case series is low (to date we have treated 60 cases), we would like to share the results obtained with this new treatment option for patients with hidradenitis suppurativa who have previously received multiple treatments, including biologic agents; our patients reported marked improvement in quality of life. We feel that it is important to make this brief comment because, once again to paraphrase the authors of the recent article, “even under treatment with these new drugs, however, the response of over half the patients with severe forms of HS will continue to be unsatisfactory.” While it is not, at present, a common technique, the addition of intralesional photodynamic therapy as a therapeutic option for the treatment of HS may be effective in many cases.</p></span>" "pdfFichero" => "main.pdf" "tienePdf" => true "NotaPie" => array:1 [ 0 => array:2 [ "etiqueta" => "☆" "nota" => "<p class="elsevierStyleNotepara" id="npar0005">Please cite this article as: González-Sixto B, Rodríguez-Prieto M. Comentario a: “Hidrosadenitis supurativa: nuevas oportunidades para una enfermedad dermatológica huérfana”. Actas Dermosifiliogr. 2015;106:860.</p>" ] ] "bibliografia" => array:2 [ "titulo" => "References" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:3 [ 0 => array:3 [ "identificador" => "bib0020" "etiqueta" => "1" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Hidrosadenitis supurativa: nuevas oportunidades para una enfermedad dermatológica huérfana" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "J.M. Carrascosa" 1 => "J. Bassas" 2 => "L. Puig" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/j.ad.2015.01.008" "Revista" => array:6 [ "tituloSerie" => "Actas Dermosifiliogr." "fecha" => "2015" "volumen" => "106" "paginaInicial" => "448" "paginaFinal" => "451" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/25796270" "web" => "Medline" ] ] ] ] ] ] ] ] 1 => array:3 [ "identificador" => "bib0025" "etiqueta" => "2" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Efficacy of intralesional photodynamic therapy for the treatment of hidradenitis suppurativa" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "M.A. Rodriguez-Prieto" 1 => "L.M. Valladares-Narganes" 2 => "B. Gonzalez-Sixto" 3 => "M. Noguerol-Cal" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/j.jaad.2012.11.030" "Revista" => array:6 [ "tituloSerie" => "J Am Acad Dermatol." "fecha" => "2013" "volumen" => "68" "paginaInicial" => "873" "paginaFinal" => "875" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/23602177" "web" => "Medline" ] ] ] ] ] ] ] ] 2 => array:3 [ "identificador" => "bib0030" "etiqueta" => "3" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Treatment of hidradenitis suppurativa with intralesional photodynamic therapy using a laser diode attached to an optical cable: a promising new approach" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "L.M. Valladares-Narganes" 1 => "M.A. Rodriguez-Prieto" 2 => "M.D. Blanco-Suarez" 3 => "C. Rodriguez-Lage" 4 => "I. Garcia-Doval" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1111/bjd.13385" "Revista" => array:6 [ "tituloSerie" => "Br J Dermatol." "fecha" => "2015" "volumen" => "172" "paginaInicial" => "1136" "paginaFinal" => "1139" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/25196140" "web" => "Medline" ] ] ] ] ] ] ] ] ] ] ] ] ] "idiomaDefecto" => "en" "url" => "/15782190/0000010600000010/v1_201512060022/S1578219015002784/v1_201512060022/en/main.assets" "Apartado" => array:4 [ "identificador" => "6202" "tipo" => "SECCION" "en" => array:2 [ "titulo" => "Letter to the Editor" "idiomaDefecto" => true ] "idiomaDefecto" => "en" ] "PDF" => "https://static.elsevier.es/multimedia/15782190/0000010600000010/v1_201512060022/S1578219015002784/v1_201512060022/en/main.pdf?idApp=UINPBA000044&text.app=https://actasdermo.org/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219015002784?idApp=UINPBA000044" ]
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