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Rodríguez Bandera, M. Mayor Arenal, K. Vorlicka, E. Ruiz Bravo-Burguilllos, D. Montero Vega, C. Vidaurrázaga Díaz-Arcaya" "autores" => array:6 [ 0 => array:4 [ "nombre" => "A.I." "apellidos" => "Rodríguez Bandera" "email" => array:1 [ 0 => "anarb85@gmail.com" ] "referencia" => array:2 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] 1 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">*</span>" "identificador" => "cor0005" ] ] ] 1 => array:3 [ "nombre" => "M." "apellidos" => "Mayor Arenal" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] ] ] 2 => array:3 [ "nombre" => "K." "apellidos" => "Vorlicka" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] ] ] 3 => array:3 [ "nombre" => "E." "apellidos" => "Ruiz Bravo-Burguilllos" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff0010" ] ] ] 4 => array:3 [ "nombre" => "D. Montero" "apellidos" => "Vega" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">c</span>" "identificador" => "aff0015" ] ] ] 5 => array:3 [ "nombre" => "C." "apellidos" => "Vidaurrázaga Díaz-Arcaya" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] ] ] ] "afiliaciones" => array:3 [ 0 => array:3 [ "entidad" => "Servicio de Dermatología, Hospital Universitario La Paz, Madrid, Spain" "etiqueta" => "a" "identificador" => "aff0005" ] 1 => array:3 [ "entidad" => "Servicio Anatomía Patológica, Hospital Universitario La Paz, Madrid, Spain" "etiqueta" => "b" "identificador" => "aff0010" ] 2 => array:3 [ "entidad" => "Servicio Microbiología, Hospital Universitario La Paz, Madrid, Spain" "etiqueta" => "c" "identificador" => "aff0015" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "⁎" "correspondencia" => "Corresponding author." ] ] ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Réplica a «Estudio retrospectivo de 49 casos de infección aguda por parvovirus B19 en adultos»" ] ] "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">In response to the previously published <span class="elsevierStyleItalic">Letter to the Editor</span>, we would like to thank the authors for their input and apologize for any misunderstandings that may have been caused by our article.</p><p id="par0010" class="elsevierStylePara elsevierViewall">We concluded our article, which was aimed primarily at dermatologists, by saying that acute parvovirus B19 infection “should be suspected in any patient with a purpuric rash, regardless of its distribution, and particularly if the patient is a young woman, seen in the spring or summer months, with fever and joint pain”. We added that “the presence of skin lesions, presenting as either nonpalpable purpura (papular-purpuric gloves and socks syndrome) or palpable purpura (probably vasculitis), is particularly suggestive.”<a class="elsevierStyleCrossRef" href="#bib0005"><span class="elsevierStyleSup">1</span></a> We stressed the importance of this dermatologic sign, not only because it was the most common clinical finding in our series, but also because it prompts patients to visit their dermatologist.</p><p id="par0015" class="elsevierStylePara elsevierViewall">That said, at no time did we wish to suggest that cutaneous lesions are the only manifestation of parvovirus B19 infection as, as was also demonstrated in our series, these lesions are present in just 55% of patients.<a class="elsevierStyleCrossRef" href="#bib0005"><span class="elsevierStyleSup">1</span></a></p><p id="par0020" class="elsevierStylePara elsevierViewall">We also took the article by Parra et al. into account, which, as can be seen, is cited in our study.<a class="elsevierStyleCrossRef" href="#bib0005"><span class="elsevierStyleSup">1</span></a></p><p id="par0025" class="elsevierStylePara elsevierViewall">We are afraid that we do not agree that papular-purpuric gloves and socks syndrome is a nondermatologic manifestation of parvovirus B19 infection. As we explain in our article, this syndrome is characterized by “erythema and swelling of the feet and hands that can cause pruritus, pain, and a burning sensation” and by “erythema that is sharply demarcated at the wrists and ankles and that progresses to purpuric lesions that spread centripetally and may be accompanied by mucosal lesions and systemic involvement.”<a class="elsevierStyleCrossRef" href="#bib0005"><span class="elsevierStyleSup">1</span></a></p><p id="par0030" class="elsevierStylePara elsevierViewall">Finally, we believe that we refer throughout the article to the different clinical manifestations (dermatologic or otherwise) and diseases with which parvovirus B19 infection has been associated, both in our series and in reports in the literature. We drew attention to the potential complications of parvovirus B19 infection, such as chronic anemia in immunodepressed patients, aplastic crisis in patients with hemoglobinopathies, and hydrops fetalis in pregnant women.<a class="elsevierStyleCrossRef" href="#bib0005"><span class="elsevierStyleSup">1</span></a> While none of the patients in our series had severe disease associated with acute parvovirus B19 infection, we did draw readers’ attention to isolated reports in the literature of, among others, “acute fulminant hepatitis, acute glomerulonephritis, acute encephalitis and peripheral neuropathy, myocarditis, and aplastic anemia in immunocompetent patients”. We also mentioned the possible association between parvovirus B19 infection and a range of autoimmune disorders described in the literature. Nevertheless, given the nature of our series, we cannot draw any conclusions in this respect.</p><p id="par0035" class="elsevierStylePara elsevierViewall">We sincerely appreciate the interest the authors have shown in our article and hope to have clarified any misunderstandings that may have arisen. We do, however, believe that any doubts can be dispelled by a careful, in-depth reading of our article, and of course we will be more than happy to hear any further contributions.</p></span>" "pdfFichero" => "main.pdf" "tienePdf" => true "NotaPie" => array:1 [ 0 => array:2 [ "etiqueta" => "☆" "nota" => "<p class="elsevierStyleNotepara" id="npar0005">Please cite this article as: Rodríguez Bandera AI, Mayor Arenal M, Vorlicka K, Ruiz Bravo-Burguilllos E, Vega DM, Vidaurrázaga Díaz-Arcaya C. Réplica a «Estudio retrospectivo de 49 casos de infección aguda por parvovirus B19 en adultos». Actas Dermosifiliogr. 2015;106:343–344.</p>" ] ] "bibliografia" => array:2 [ "titulo" => "Reference" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:1 [ 0 => array:3 [ "identificador" => "bib0005" "etiqueta" => "1" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Estudio retrospectivo de 49 casos de infección aguda por parvovirus B19 en adultos" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "A.I. Rodríguez Bandera" 1 => "M. Mayor Arenal" 2 => "K. Vorlicka" 3 => "E. Ruiz-Bravo Burguillos" 4 => "D. Montero Vega" 5 => "C. Vidaurrázaga Díaz-Arcaya" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:3 [ "tituloSerie" => "Actas Dermosifiliogr" "fecha" => "2014 en prensa" "itemHostRev" => array:3 [ "pii" => "S0213005X09001244" "estado" => "S300" "issn" => "0213005X" ] ] ] ] ] ] ] ] ] ] ] ] "idiomaDefecto" => "en" "url" => "/15782190/0000010600000004/v2_201505051007/S1578219015000682/v2_201505051007/en/main.assets" "Apartado" => array:4 [ "identificador" => "6208" "tipo" => "SECCION" "en" => array:2 [ "titulo" => "Letters to the Editor" "idiomaDefecto" => true ] "idiomaDefecto" => "en" ] "PDF" => "https://static.elsevier.es/multimedia/15782190/0000010600000004/v2_201505051007/S1578219015000682/v2_201505051007/en/main.pdf?idApp=UINPBA000044&text.app=https://actasdermo.org/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219015000682?idApp=UINPBA000044" ]
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