Case and Research Letters
Old World Leishmaniasis on the Ear Lobe: A Rare Site
Infección del lóbulo auricular por Leishmania en el Viejo Mundo: una localización excepcional
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En el citoplasma de los histiocitos se identifican estructuras puntiformes basófilas (flecha) correspondientes a <span class="elsevierStyleItalic">Leishmania</span> (tinción Giemsa ×<span class="elsevierStyleHsp" style=""></span>40).</p>" ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "G. Blasco Morente, J. Rodríguez-Granger, J. Tercedor Sánchez, J.M. Latorre Fuentes" "autores" => array:4 [ 0 => array:2 [ "nombre" => "G." "apellidos" => "Blasco Morente" ] 1 => array:2 [ "nombre" => "J." "apellidos" => "Rodríguez-Granger" ] 2 => array:2 [ "nombre" => "J." "apellidos" => "Tercedor Sánchez" ] 3 => array:2 [ "nombre" => "J.M." 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Ruiz-Villaverde, M. Galán-Gutierrez, F. Ramos-Pleguezuelos, J.M. Martinez de Victoria" "autores" => array:4 [ 0 => array:2 [ "nombre" => "R." "apellidos" => "Ruiz-Villaverde" ] 1 => array:2 [ "nombre" => "M." "apellidos" => "Galán-Gutierrez" ] 2 => array:2 [ "nombre" => "F." "apellidos" => "Ramos-Pleguezuelos" ] 3 => array:2 [ "nombre" => "J.M." "apellidos" => "Martinez de Victoria" ] ] ] ] ] "idiomaDefecto" => "en" "Traduccion" => array:1 [ "es" => array:9 [ "pii" => "S0001731013003232" "doi" => "10.1016/j.ad.2013.08.010" "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:1 [ "total" => 0 ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0001731013003232?idApp=UINPBA000044" ] ] "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219014001371?idApp=UINPBA000044" "url" => "/15782190/0000010500000006/v1_201406280124/S1578219014001371/v1_201406280124/en/main.assets" ] "itemAnterior" => array:19 [ "pii" => "S157821901400136X" "issn" => "15782190" "doi" => "10.1016/j.adengl.2014.05.002" "estado" => "S300" "fechaPublicacion" => "2014-07-01" "aid" => "883" "copyright" => "Elsevier España, S.L. and AEDV" "documento" => "simple-article" "crossmark" => 0 "subdocumento" => "cor" "cita" => "Actas Dermosifiliogr. 2014;105:626-8" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 1415 "formatos" => array:3 [ "EPUB" => 40 "HTML" => 1062 "PDF" => 313 ] ] "en" => array:11 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Case and Research Letters</span>" "titulo" => "Eosinophilic Fasciitis: An Uncommon Cause of Edema" "tienePdf" => "en" "tieneTextoCompleto" => "en" "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "626" "paginaFinal" => "628" ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Fascitis eosinofílica: causa infrecuente de edemas" ] ] "contieneTextoCompleto" => array:1 [ "en" => true ] "contienePdf" => array:1 [ "en" => true ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:7 [ "identificador" => "fig0005" "etiqueta" => "Figure 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 690 "Ancho" => 1034 "Tamanyo" => 73509 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Edema of the right arm; note the dimpled appearance of the skin of the inner arm and the increased diameter of the forearm.</p>" ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "M. Utrera-Busquets, J.C. Tardio, A. Curcio-Ruigomez, J. Borbujo-Martínez" "autores" => array:4 [ 0 => array:2 [ "nombre" => "M." "apellidos" => "Utrera-Busquets" ] 1 => array:2 [ "nombre" => "J.C." "apellidos" => "Tardio" ] 2 => array:2 [ "nombre" => "A." "apellidos" => "Curcio-Ruigomez" ] 3 => array:2 [ "nombre" => "J." 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Blasco Morente, J. Rodríguez-Granger, J. Tercedor Sánchez, J.M. Latorre Fuentes" "autores" => array:4 [ 0 => array:4 [ "nombre" => "G." "apellidos" => "Blasco Morente" "email" => array:1 [ 0 => "gonzaloblascomorente@gmail.com" ] "referencia" => array:2 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] 1 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">¿</span>" "identificador" => "cor0005" ] ] ] 1 => array:3 [ "nombre" => "J." "apellidos" => "Rodríguez-Granger" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff0010" ] ] ] 2 => array:3 [ "nombre" => "J." "apellidos" => "Tercedor Sánchez" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] ] ] 3 => array:3 [ "nombre" => "J.M." "apellidos" => "Latorre Fuentes" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] ] ] ] "afiliaciones" => array:2 [ 0 => array:3 [ "entidad" => "Unidad de Gestión Clínica de Dermatología Médico Quirúrgica y Venereología, Hospital Virgen de las Nieves, Granada, Spain" "etiqueta" => "a" "identificador" => "aff0005" ] 1 => array:3 [ "entidad" => "Unidad de Gestión Clínica Microbiología, Hospital Virgen de las Nieves, Granada, Spain" "etiqueta" => "b" "identificador" => "aff0010" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "⁎" "correspondencia" => "Corresponding author." ] ] ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Infección del lóbulo auricular por <span class="elsevierStyleItalic">Leishmania</span> en el Viejo Mundo: una localización excepcional" ] ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:7 [ "identificador" => "fig0005" "etiqueta" => "Figure 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 562 "Ancho" => 1440 "Tamanyo" => 165423 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Front and side views. A, Erythematous infiltrated plaque of 16<span class="elsevierStyleHsp" style=""></span>×<span class="elsevierStyleHsp" style=""></span>25<span class="elsevierStyleHsp" style=""></span>mm on the left ear lobe with central ulceration and a seropurulent crust and coalescing pustules on the antihelix. B, Soft edema and hyperemic nodular infiltration (9.5<span class="elsevierStyleHsp" style=""></span>×<span class="elsevierStyleHsp" style=""></span>10<span class="elsevierStyleHsp" style=""></span>mm) of the right ear lobe.</p>" ] ] ] "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">Leishmaniasis is a parasitic disease caused by protozoan species of the genus <span class="elsevierStyleItalic">Leishmania</span>. Its geographical distribution can be divided into 2 general areas; the New World (Mexico, Central America and South America) and the Old World (Asia, Africa and Southern Europe).<a class="elsevierStyleCrossRef" href="#bib0005"><span class="elsevierStyleSup">1</span></a> The clinical spectrum depends on the pathogenicity of the <span class="elsevierStyleItalic">Leishmania</span> species and the immune response of the host.<a class="elsevierStyleCrossRef" href="#bib0010"><span class="elsevierStyleSup">2</span></a> Cutaneous leishmaniasis (CL) is the most common and mildest clinical form, accounting for between 50% and 75% of cases.<a class="elsevierStyleCrossRefs" href="#bib0005"><span class="elsevierStyleSup">1,2</span></a> Atrial involvement is very rare; only a few cases have been described in the Old World, none of which exclusively affected the ear lobe. We report 2 cases of CL with ear lobe involvement (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>, A and B).</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0005">Case 1</span><p id="par0010" class="elsevierStylePara elsevierViewall">A 73-year-old woman presented with a painful lesion on the pinna that had developed 7 months previously. Physical examination revealed an erythematous infiltrated plaque with central ulceration and a seropurulent crust on the left ear lobe and coalescing pustules on the antihelix (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>A). <span class="elsevierStyleItalic">Leishmania</span> species was visualized by Giemsa staining of the biopsy imprint. Histopathology revealed the presence of intracytoplasmic basophilic punctate structures within histiocytes that were compatible with amastigotes (<a class="elsevierStyleCrossRef" href="#fig0010">Fig. 2</a>). Intramuscular meglumine antimoniate (MA; 60<span class="elsevierStyleHsp" style=""></span>mg/kg/d) was administered for 12 days; this regimen was repeated 2 weeks later, followed by cryotherapy of the residual lesion, resulting in cure.</p><elsevierMultimedia ident="fig0010"></elsevierMultimedia></span><span id="sec0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0010">Case 2</span><p id="par0015" class="elsevierStylePara elsevierViewall">An 86-year-old man presented with a painful lesion on the ear lobe of 4 months’ duration. Examination revealed soft edema and hyperemic nodular infiltration of the right ear lobe (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>B). Direct smear revealed the presence of <span class="elsevierStyleItalic">Leishmania</span> amastigotes. Promastigote forms of <span class="elsevierStyleItalic">Leishmania</span> grew in culture within a few days, and were characterized as <span class="elsevierStyleItalic">Leishmania infantum</span> by polymerase chain reaction with enzyme-linked immunosorbent assay. Histological analysis of an infiltrated margin showed collections of histiocytes and the presence of <span class="elsevierStyleItalic">Leishmania</span> bodies. The patient was treated with 2 intralesional injections of MA separated by 15 days. Cure of the lesion was achieved 2 months after completion of the treatment.</p><p id="par0020" class="elsevierStylePara elsevierViewall">CL has an incidence of 1.5 million new cases per year.<a class="elsevierStyleCrossRefs" href="#bib0015"><span class="elsevierStyleSup">3,4</span></a> The vast majority of cases (90%) occur in 7 countries: Afghanistan, Saudi Arabia, Iran, Iraq, Algeria, Pakistan, and Peru.<a class="elsevierStyleCrossRef" href="#bib0020"><span class="elsevierStyleSup">4</span></a> In Spain the disease is considered hypoendemic (mainly affecting the Mediterranean coast, Castile and León, and Aragón); its incidence (0.4 cases per 100 000 inhabitants per year) is increasing due to migration, environmental changes, and the development of immunosuppressive conditions.<a class="elsevierStyleCrossRef" href="#bib0025"><span class="elsevierStyleSup">5</span></a></p><p id="par0025" class="elsevierStylePara elsevierViewall">In the Old World the clinical presentation of CL is known as <span class="elsevierStyleItalic">oriental sore.</span> A single lesion develops in 58% to 70% of patients. Lesions are usually located in exposed areas, such as the upper extremities (40%-45%), head and neck (18%-37%), and lower extremities (6%-23%).<a class="elsevierStyleCrossRefs" href="#bib0005"><span class="elsevierStyleSup">1,3</span></a> Ear lobe involvement is typical in cases from southeastern Mexico and Central America (chiclero ulcer), and is usually caused by <span class="elsevierStyleItalic">Leishmania mexicana</span> complex, which accounts for 5% of all CL cases.<a class="elsevierStyleCrossRefs" href="#bib0005"><span class="elsevierStyleSup">1,4,6</span></a> Involvement of the ear lobe is very rare in cases of Old World leishmaniasis, as summarized in <a class="elsevierStyleCrossRef" href="#tbl0005">Table 1</a>.</p><elsevierMultimedia ident="tbl0005"></elsevierMultimedia><p id="par0030" class="elsevierStylePara elsevierViewall">The cases of CL affecting the ear lobe described here involved elderly (73 and 86 years of age), immunocompetent patients from rural populations. The clinical features of the first patient were a torpid infiltrated plaque with ulceration and crusting that had appeared more than 6 months earlier. The second patient presented with a nodule that had developed shortly beforehand. The clinical course of the cases described in <a class="elsevierStyleCrossRef" href="#tbl0005">Table 1</a> ranged from 2 to 16 months. Diagnosis was delayed due to the atypical presentation, and was usually established only after several medical visits. Treatment in most cases was with intramuscular pentavalent antimonials, given the tendency towards chronicity and the risk of deformity at the site of the lesion, although intralesional administration can also bring about complete resolution of the lesion.</p><p id="par0035" class="elsevierStylePara elsevierViewall">The differential diagnosis of ulcerative lesions of the ear is broad, and includes acute lesions (eg, infections, Winkler disease, bites, sarcoidosis, granulomas, and neoplasms) and chronic lesions (eg, lupus vulgaris, discoid lupus, leprosy, and lymphoma).<a class="elsevierStyleCrossRefs" href="#bib0005"><span class="elsevierStyleSup">1–4,6–10</span></a> Clinical history is very important for diagnosis, which should be confirmed by microbiological studies and molecular biology techniques.<a class="elsevierStyleCrossRef" href="#bib0020"><span class="elsevierStyleSup">4</span></a></p><p id="par0040" class="elsevierStylePara elsevierViewall">Old World CL usually heals spontaneously within 3 to 18 months, leaving a scar.<a class="elsevierStyleCrossRefs" href="#bib0005"><span class="elsevierStyleSup">1,6</span></a> Treatment is indicated in cases that involve multiple or large lesions, persist for more than 6 months (chronic CL), or affect regions at risk of functional or aesthetic compromise, such as the ear lobe.<a class="elsevierStyleCrossRefs" href="#bib0015"><span class="elsevierStyleSup">3,6</span></a> Localized forms are treated using local treatments such as intralesional MA (Case 2), the efficacy of which can be very high, albeit variable.<a class="elsevierStyleCrossRefs" href="#bib0005"><span class="elsevierStyleSup">1,2,6</span></a> The treatment of choice for chronic forms is parenteral pentavalent antimonials,<a class="elsevierStyleCrossRef" href="#bib0015"><span class="elsevierStyleSup">3</span></a> which can be complemented with local treatments such as cryotherapy, as described in Case 1.</p><p id="par0045" class="elsevierStylePara elsevierViewall">Rapid recognition of this disease can permit earlier treatment, decreasing the likelihood of the development of residual lesions.</p></span></span>" "textoCompletoSecciones" => array:1 [ "secciones" => array:3 [ 0 => array:2 [ "identificador" => "sec0005" "titulo" => "Case 1" ] 1 => array:2 [ "identificador" => "sec0010" "titulo" => "Case 2" ] 2 => array:1 [ "titulo" => "References" ] ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "NotaPie" => array:1 [ 0 => array:2 [ "etiqueta" => "☆" "nota" => "<p class="elsevierStyleNotepara" id="npar0005">Please cite this article as: Blasco Morente G, Rodríguez-Granger J, Tercedor Sánchez J, Latorre Fuentes JM. Infección del lóbulo auricular por <span class="elsevierStyleItalic">Leishmania</span> en el Viejo Mundo: una localización excepcional. Actas Dermosifiliogr. 2014;105:628–630.</p>" ] ] "multimedia" => array:3 [ 0 => array:7 [ "identificador" => "fig0005" "etiqueta" => "Figure 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 562 "Ancho" => 1440 "Tamanyo" => 165423 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Front and side views. A, Erythematous infiltrated plaque of 16<span class="elsevierStyleHsp" style=""></span>×<span class="elsevierStyleHsp" style=""></span>25<span class="elsevierStyleHsp" style=""></span>mm on the left ear lobe with central ulceration and a seropurulent crust and coalescing pustules on the antihelix. B, Soft edema and hyperemic nodular infiltration (9.5<span class="elsevierStyleHsp" style=""></span>×<span class="elsevierStyleHsp" style=""></span>10<span class="elsevierStyleHsp" style=""></span>mm) of the right ear lobe.</p>" ] ] 1 => array:7 [ "identificador" => "fig0010" "etiqueta" => "Figure 2" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr2.jpeg" "Alto" => 655 "Ancho" => 1009 "Tamanyo" => 309091 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Histopathology: skin with dense inflammatory infiltrate (lymphocytes, histiocytes, and plasma cells) occupying the entire dermis. Basophilic punctate structures (arrow) corresponding to <span class="elsevierStyleItalic">Leishmania</span> species can be seen in the cytoplasm of the histiocytes (Giemsa staining, original magnification ×40).</p>" ] ] 2 => array:7 [ "identificador" => "tbl0005" "etiqueta" => "Table 1" "tipo" => "MULTIMEDIATABLA" "mostrarFloat" => true "mostrarDisplay" => false "tabla" => array:2 [ "leyenda" => "<p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">Abbreviations: F, female; IM, intramuscular; M, male; MA, meglumine antimoniate.</p>" "tablatextoimagen" => array:1 [ 0 => array:2 [ "tabla" => array:1 [ 0 => """ <table border="0" frame="\n \t\t\t\t\tvoid\n \t\t\t\t" class=""><thead title="thead"><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-head\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t" style="border-bottom: 2px solid black">Authors \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-head\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t" style="border-bottom: 2px solid black">Year \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-head\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t" style="border-bottom: 2px solid black">Country \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-head\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t" style="border-bottom: 2px solid black">Age, y \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-head\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t" style="border-bottom: 2px solid black">Sex \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-head\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t" style="border-bottom: 2px solid black">Prior Medical History \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-head\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t" style="border-bottom: 2px solid black">Location \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-head\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t" style="border-bottom: 2px solid black">Time Since Onset, mo \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-head\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t" style="border-bottom: 2px solid black">Treatment \t\t\t\t\t\t\n \t\t\t\t</td></tr></thead><tbody title="tbody"><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Skevas et al.<a class="elsevierStyleCrossRef" href="#bib0035"><span class="elsevierStyleSup">7</span></a> \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">1997 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Albania \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">32 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">M \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Immunocompetent \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Left pinna \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">16 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">MA, 60<span class="elsevierStyleHsp" style=""></span>mg/kg/d IM for 20 d \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Martinelli et al.<a class="elsevierStyleCrossRef" href="#bib0040"><span class="elsevierStyleSup">8</span></a> \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">2005 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Italy \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">66 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">M \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Immunocompetent \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Right helix \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">12 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">MA, 60 mg/kg/d IM for 15 d; 2 cycles 15 d apart \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Fagundo Gonzalez et al.<a class="elsevierStyleCrossRef" href="#bib0015"><span class="elsevierStyleSup">3</span></a> \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">2005 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Spain \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">48 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">F \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Immunocompetent \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Right helix and antihelix \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">2 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">MA, 1.5<span class="elsevierStyleHsp" style=""></span>g/d IM for 2<span class="elsevierStyleHsp" style=""></span>wk; 3 cycles, each 15 d apart \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Quante et al.<a class="elsevierStyleCrossRef" href="#bib0045"><span class="elsevierStyleSup">9</span></a> \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">2006 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Cyprus \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">- \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">M \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Immunocompetent \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Entire pinna \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">- \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">- \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Van Der Vliet et al.<a class="elsevierStyleCrossRef" href="#bib0050"><span class="elsevierStyleSup">10</span></a> \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">2006 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">France \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">28 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">M \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Immunocompetent \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Right helix \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">2 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">MA, 20<span class="elsevierStyleHsp" style=""></span>mg/kg/d IM for 13 d plus 2 intralesional injections \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Khorsandi Ashtiani et al.<a class="elsevierStyleCrossRef" href="#bib0020"><span class="elsevierStyleSup">4</span></a> \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">2008 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Iran \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">42 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">M \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Diabetes mellitus, hypertension \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Entire pinna, left ear \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">2 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">MA, 20<span class="elsevierStyleHsp" style=""></span>mg/kg/d IM for 3<span class="elsevierStyleHsp" style=""></span>wk; 2 cycles 3<span class="elsevierStyleHsp" style=""></span>wk apart \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Sabri et al.<a class="elsevierStyleCrossRef" href="#bib0005"><span class="elsevierStyleSup">1</span></a> \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">2009 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Syria \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">73 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">M \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Immunocompetent \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Left helix \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">2 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">- \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Robati et al.<a class="elsevierStyleCrossRef" href="#bib0010"><span class="elsevierStyleSup">2</span></a> \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">2011 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Iran \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">35 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">M \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Immunocompetent \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Left helix and antihelix \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">6 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">MA, IM \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Tarkan et al.<a class="elsevierStyleCrossRef" href="#bib0030"><span class="elsevierStyleSup">6</span></a> \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">2012 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Turkey \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">35 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">M \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Immunocompetent \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Right helix and pinna \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">- \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">MA, 15<span class="elsevierStyleHsp" style=""></span>mg/kg/d IM for 15 d \t\t\t\t\t\t\n \t\t\t\t</td></tr></tbody></table> """ ] "imagenFichero" => array:1 [ 0 => "xTab521017.png" ] ] ] ] "descripcion" => array:1 [ "en" => "<p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">Cases of Leishmaniasis With Ear Lobe Involvement Described in the Old World.</p>" ] ] ] "bibliografia" => array:2 [ "titulo" => "References" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:10 [ 0 => array:3 [ "identificador" => "bib0005" "etiqueta" => "1" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Leishmaniasis of the auricle mimicking carcinoma" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "A. 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| año/Mes | Html | Total | |
|---|---|---|---|
| 2024 Noviembre | 11 | 12 | 23 |
| 2024 Octubre | 82 | 42 | 124 |
| 2024 Septiembre | 114 | 39 | 153 |
| 2024 Agosto | 149 | 54 | 203 |
| 2024 Julio | 98 | 50 | 148 |
| 2024 Junio | 125 | 40 | 165 |
| 2024 Mayo | 96 | 43 | 139 |
| 2024 Abril | 78 | 18 | 96 |
| 2024 Marzo | 87 | 28 | 115 |
| 2024 Febrero | 92 | 34 | 126 |
| 2024 Enero | 67 | 32 | 99 |
| 2023 Diciembre | 70 | 25 | 95 |
| 2023 Noviembre | 92 | 33 | 125 |
| 2023 Octubre | 82 | 24 | 106 |
| 2023 Septiembre | 85 | 37 | 122 |
| 2023 Agosto | 63 | 24 | 87 |
| 2023 Julio | 89 | 37 | 126 |
| 2023 Junio | 75 | 24 | 99 |
| 2023 Mayo | 76 | 27 | 103 |
| 2023 Abril | 65 | 16 | 81 |
| 2023 Marzo | 63 | 36 | 99 |
| 2023 Febrero | 72 | 32 | 104 |
| 2023 Enero | 52 | 30 | 82 |
| 2022 Diciembre | 76 | 42 | 118 |
| 2022 Noviembre | 50 | 41 | 91 |
| 2022 Octubre | 33 | 40 | 73 |
| 2022 Septiembre | 41 | 42 | 83 |
| 2022 Agosto | 45 | 47 | 92 |
| 2022 Julio | 42 | 39 | 81 |
| 2022 Junio | 39 | 24 | 63 |
| 2022 Mayo | 60 | 39 | 99 |
| 2022 Abril | 51 | 34 | 85 |
| 2022 Marzo | 68 | 41 | 109 |
| 2022 Febrero | 56 | 13 | 69 |
| 2022 Enero | 62 | 39 | 101 |
| 2021 Diciembre | 39 | 27 | 66 |
| 2021 Noviembre | 54 | 50 | 104 |
| 2021 Octubre | 51 | 54 | 105 |
| 2021 Septiembre | 45 | 40 | 85 |
| 2021 Agosto | 61 | 47 | 108 |
| 2021 Julio | 42 | 46 | 88 |
| 2021 Junio | 43 | 23 | 66 |
| 2021 Mayo | 40 | 27 | 67 |
| 2021 Abril | 109 | 48 | 157 |
| 2021 Marzo | 92 | 20 | 112 |
| 2021 Febrero | 66 | 19 | 85 |
| 2021 Enero | 34 | 11 | 45 |
| 2020 Diciembre | 51 | 9 | 60 |
| 2020 Noviembre | 29 | 5 | 34 |
| 2020 Octubre | 32 | 14 | 46 |
| 2020 Septiembre | 26 | 15 | 41 |
| 2020 Agosto | 26 | 12 | 38 |
| 2020 Julio | 24 | 9 | 33 |
| 2020 Junio | 38 | 22 | 60 |
| 2020 Mayo | 21 | 15 | 36 |
| 2020 Abril | 25 | 11 | 36 |
| 2020 Marzo | 26 | 11 | 37 |
| 2020 Febrero | 1 | 4 | 5 |
| 2020 Enero | 4 | 2 | 6 |
| 2019 Diciembre | 8 | 1 | 9 |
| 2019 Noviembre | 4 | 3 | 7 |
| 2019 Octubre | 0 | 2 | 2 |
| 2019 Septiembre | 4 | 2 | 6 |
| 2019 Agosto | 4 | 0 | 4 |
| 2019 Julio | 4 | 1 | 5 |
| 2019 Junio | 6 | 3 | 9 |
| 2019 Mayo | 4 | 14 | 18 |
| 2019 Abril | 2 | 4 | 6 |
| 2019 Marzo | 4 | 18 | 22 |
| 2019 Febrero | 2 | 0 | 2 |
| 2019 Enero | 4 | 0 | 4 |
| 2018 Diciembre | 1 | 4 | 5 |
| 2018 Noviembre | 4 | 1 | 5 |
| 2018 Octubre | 4 | 0 | 4 |
| 2018 Septiembre | 2 | 5 | 7 |
| 2018 Agosto | 0 | 12 | 12 |
| 2018 Julio | 0 | 4 | 4 |
| 2018 Junio | 0 | 1 | 1 |
| 2018 Mayo | 0 | 13 | 13 |
| 2018 Abril | 0 | 1 | 1 |
| 2018 Marzo | 14 | 2 | 16 |
| 2018 Febrero | 41 | 7 | 48 |
| 2018 Enero | 57 | 5 | 62 |
| 2017 Diciembre | 66 | 5 | 71 |
| 2017 Noviembre | 36 | 11 | 47 |
| 2017 Octubre | 23 | 6 | 29 |
| 2017 Septiembre | 47 | 9 | 56 |
| 2017 Agosto | 52 | 7 | 59 |
| 2017 Julio | 46 | 9 | 55 |
| 2017 Junio | 69 | 20 | 89 |
| 2017 Mayo | 67 | 21 | 88 |
| 2017 Abril | 52 | 13 | 65 |
| 2017 Marzo | 59 | 16 | 75 |
| 2017 Febrero | 41 | 16 | 57 |
| 2017 Enero | 35 | 21 | 56 |
| 2016 Diciembre | 42 | 16 | 58 |
| 2016 Noviembre | 64 | 19 | 83 |
| 2016 Octubre | 86 | 15 | 101 |
| 2016 Septiembre | 151 | 3 | 154 |
| 2016 Agosto | 73 | 10 | 83 |
| 2016 Julio | 27 | 5 | 32 |
| 2016 Junio | 6 | 13 | 19 |
| 2016 Mayo | 9 | 8 | 17 |
| 2016 Abril | 5 | 24 | 29 |
| 2016 Marzo | 5 | 1 | 6 |
| 2016 Febrero | 10 | 1 | 11 |
| 2016 Enero | 10 | 15 | 25 |
| 2015 Diciembre | 13 | 1 | 14 |
| 2015 Noviembre | 11 | 11 | 22 |
| 2015 Octubre | 15 | 2 | 17 |
| 2015 Septiembre | 11 | 4 | 15 |
| 2015 Agosto | 15 | 4 | 19 |
| 2015 Julio | 97 | 7 | 104 |
| 2015 Junio | 38 | 1 | 39 |
| 2015 Mayo | 50 | 4 | 54 |
| 2015 Abril | 28 | 4 | 32 |
| 2015 Marzo | 32 | 6 | 38 |
| 2015 Febrero | 36 | 8 | 44 |
| 2015 Enero | 16 | 2 | 18 |
| 2014 Diciembre | 18 | 4 | 22 |
| 2014 Noviembre | 13 | 1 | 14 |
| 2014 Octubre | 11 | 2 | 13 |
| 2014 Agosto | 0 | 1 | 1 |
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