array:23 [
  "pii" => "S1578219014000948"
  "issn" => "15782190"
  "doi" => "10.1016/j.adengl.2014.02.001"
  "estado" => "S300"
  "fechaPublicacion" => "2014-05-01"
  "aid" => "953"
  "copyright" => "Elsevier España, S.L. and AEDV"
  "copyrightAnyo" => "2014"
  "documento" => "simple-article"
  "crossmark" => 0
  "subdocumento" => "cor"
  "cita" => "Actas Dermosifiliogr. 2014;105:434"
  "abierto" => array:3 [
    "ES" => true
    "ES2" => true
    "LATM" => true
  ]
  "gratuito" => true
  "lecturas" => array:2 [
    "total" => 1277
    "formatos" => array:3 [
      "EPUB" => 41
      "HTML" => 925
      "PDF" => 311
    ]
  ]
  "Traduccion" => array:1 [
    "es" => array:19 [
      "pii" => "S0001731014000295"
      "issn" => "00017310"
      "doi" => "10.1016/j.ad.2014.02.001"
      "estado" => "S300"
      "fechaPublicacion" => "2014-05-01"
      "aid" => "953"
      "copyright" => "Elsevier España, S.L. y AEDV"
      "documento" => "simple-article"
      "crossmark" => 0
      "subdocumento" => "cor"
      "cita" => "Actas Dermosifiliogr. 2014;105:434"
      "abierto" => array:3 [
        "ES" => true
        "ES2" => true
        "LATM" => true
      ]
      "gratuito" => true
      "lecturas" => array:2 [
        "total" => 1262
        "formatos" => array:3 [
          "EPUB" => 2
          "HTML" => 966
          "PDF" => 294
        ]
      ]
      "es" => array:10 [
        "idiomaDefecto" => true
        "cabecera" => "<span class="elsevierStyleTextfn">Carta al Director</span>"
        "titulo" => "R&#233;plica a &#171;Melanoma d&#233;rmico solitario y estadio IIIC&#187;"
        "tienePdf" => "es"
        "tieneTextoCompleto" => "es"
        "paginas" => array:1 [
          0 => array:1 [
            "paginaInicial" => "434"
          ]
        ]
        "titulosAlternativos" => array:1 [
          "en" => array:1 [
            "titulo" => "Response to &#8220;Stage IIIC Solitary Dermal Melanoma&#8221;"
          ]
        ]
        "contieneTextoCompleto" => array:1 [
          "es" => true
        ]
        "contienePdf" => array:1 [
          "es" => true
        ]
        "autores" => array:1 [
          0 => array:2 [
            "autoresLista" => "M&#46; Gonz&#225;lez de Arriba"
            "autores" => array:1 [
              0 => array:2 [
                "nombre" => "M&#46;"
                "apellidos" => "Gonz&#225;lez de Arriba"
              ]
            ]
          ]
        ]
      ]
      "idiomaDefecto" => "es"
      "Traduccion" => array:1 [
        "en" => array:9 [
          "pii" => "S1578219014000948"
          "doi" => "10.1016/j.adengl.2014.02.001"
          "estado" => "S300"
          "subdocumento" => ""
          "abierto" => array:3 [
            "ES" => true
            "ES2" => true
            "LATM" => true
          ]
          "gratuito" => true
          "lecturas" => array:1 [
            "total" => 0
          ]
          "idiomaDefecto" => "en"
          "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219014000948?idApp=UINPBA000044"
        ]
      ]
      "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0001731014000295?idApp=UINPBA000044"
      "url" => "/00017310/0000010500000004/v1_201404301030/S0001731014000295/v1_201404301030/es/main.assets"
    ]
  ]
  "itemAnterior" => array:19 [
    "pii" => "S1578219014000936"
    "issn" => "15782190"
    "doi" => "10.1016/j.adengl.2013.12.003"
    "estado" => "S300"
    "fechaPublicacion" => "2014-05-01"
    "aid" => "952"
    "copyright" => "Elsevier Espa&#241;a&#44; S&#46;L&#46; and AEDV"
    "documento" => "simple-article"
    "crossmark" => 0
    "subdocumento" => "cor"
    "cita" => "Actas Dermosifiliogr. 2014;105:433-4"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:2 [
      "total" => 1467
      "formatos" => array:3 [
        "EPUB" => 35
        "HTML" => 1014
        "PDF" => 418
      ]
    ]
    "en" => array:10 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">Letter to the Editor</span>"
      "titulo" => "Stage IIIC Solitary Dermal Melanoma"
      "tienePdf" => "en"
      "tieneTextoCompleto" => "en"
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "433"
          "paginaFinal" => "434"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "es" => array:1 [
          "titulo" => "Melanoma d&#233;rmico solitario y estadio IIIC"
        ]
      ]
      "contieneTextoCompleto" => array:1 [
        "en" => true
      ]
      "contienePdf" => array:1 [
        "en" => true
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "E&#46; Piqu&#233;-Duran"
          "autores" => array:1 [
            0 => array:2 [
              "nombre" => "E&#46;"
              "apellidos" => "Piqu&#233;-Duran"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "en"
    "Traduccion" => array:1 [
      "es" => array:9 [
        "pii" => "S0001731014000283"
        "doi" => "10.1016/j.ad.2013.12.012"
        "estado" => "S300"
        "subdocumento" => ""
        "abierto" => array:3 [
          "ES" => true
          "ES2" => true
          "LATM" => true
        ]
        "gratuito" => true
        "lecturas" => array:1 [
          "total" => 0
        ]
        "idiomaDefecto" => "es"
        "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0001731014000283?idApp=UINPBA000044"
      ]
    ]
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219014000936?idApp=UINPBA000044"
    "url" => "/15782190/0000010500000004/v1_201404301027/S1578219014000936/v1_201404301027/en/main.assets"
  ]
  "en" => array:13 [
    "idiomaDefecto" => true
    "cabecera" => "<span class="elsevierStyleTextfn">Letter to the Editor</span>"
    "titulo" => "Response to &#8220;Stage IIIC Solitary Dermal Melanoma&#8221;"
    "tieneTextoCompleto" => true
    "saludo" => "To the Editor&#58;"
    "paginas" => array:1 [
      0 => array:1 [
        "paginaInicial" => "434"
      ]
    ]
    "autores" => array:1 [
      0 => array:3 [
        "autoresLista" => "M&#46; Gonz&#225;lez de Arriba"
        "autores" => array:1 [
          0 => array:3 [
            "nombre" => "M&#46;"
            "apellidos" => "Gonz&#225;lez de Arriba"
            "email" => array:1 [
              0 => "mgdearriba&#64;yahoo&#46;es"
            ]
          ]
        ]
        "afiliaciones" => array:1 [
          0 => array:2 [
            "entidad" => "Servicio de Dermatolog&#237;a&#44; Hospital Cl&#237;nico Universitario de Salamanca&#44; Salamanca&#44; Spain"
            "identificador" => "aff0005"
          ]
        ]
      ]
    ]
    "titulosAlternativos" => array:1 [
      "es" => array:1 [
        "titulo" => "R&#233;plica a &#171;Melanoma d&#233;rmico solitario y estadio IIIC&#187;"
      ]
    ]
    "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">We thank the author for his interest in our article and find his observations very interesting and enlightening&#46; However&#44; we believe it necessary to make some clarifications&#46;</p><p id="par0010" class="elsevierStylePara elsevierViewall">Even before the publication of the 2009 American Joint Committee on Cancer &#40;AJCC&#41; Staging and Classification&#44; various authors had studied melanoma metastasis from an unknown primary site and concluded that survival in such cases was higher than in known primary cutaneous melanomas and metastases with a similar clinical presentation&#46;</p><p id="par0015" class="elsevierStylePara elsevierViewall">This improved survival has been reported for metastases in the skin and subcutaneous tissue and for local lymph node disease with an unknown primary site&#46; The survival rates are similar to those expected for regional disease &#40;stage III&#41; and nonmetastatic disease&#46;<a class="elsevierStyleCrossRefs" href="#bib0005"><span class="elsevierStyleSup">1&#8211;3</span></a></p><p id="par0020" class="elsevierStylePara elsevierViewall">In the latest AJCC classification&#44; single skin or subcutaneous metastases are considered to be satellite or in-transit metastases&#44; while metastases in the lymph nodes are considered to be regional&#46; In both cases they are categorized as stage III and are therefore associated with higher survival rates&#46;<a class="elsevierStyleCrossRef" href="#bib0020"><span class="elsevierStyleSup">4</span></a></p><p id="par0025" class="elsevierStylePara elsevierViewall">This classification&#44; however&#44; is based only on the observation of better survival in such cases and no consideration is given to the origin of these cutaneous or subcutaneous lesions classified as satellite or in-transit &#40;and therefore metastatic&#41; lesions&#46;</p><p id="par0030" class="elsevierStylePara elsevierViewall">We are interested in the fact that these lesions might also have a primary origin&#44; as this would have new implications for the management of patients beyond a mere classification determining survival and prognosis&#46; As reported by Lee et al&#46;&#44;<a class="elsevierStyleCrossRef" href="#bib0025"><span class="elsevierStyleSup">5</span></a> 23&#37; of patients with solitary dermal melanoma &#40;SDM&#41; may have nodal disease at the time of diagnosis or later and would therefore benefit from sentinel node biopsy and&#44; if indicated&#44; lymphadenectomy&#46; It is noteworthy that sentinel node biopsy would not be indicated if the disease was already considered to be metastatic&#44; although lymphadenectomy might be an option if there is nodal involvement following on from an in-transit metastasis&#46;</p><p id="par0035" class="elsevierStylePara elsevierViewall">Given the different potential origins of a single focus of melanoma in the dermis or subcutaneous tissue&#44; we agree that a diagnosis of primary dermal melanoma is just one option when faced with SDM&#46;</p></span>"
    "pdfFichero" => "main.pdf"
    "tienePdf" => true
    "NotaPie" => array:1 [
      0 => array:2 [
        "etiqueta" => "&#9734;"
        "nota" => "<p class="elsevierStyleNotepara" id="npar0005">Please cite this article as&#58; Gonz&#225;lez de Arriba M&#46; R&#233;plica a &#171;Melanoma d&#233;rmico solitario y estadio IIIC&#187;&#46; Actas Dermosifiliogr&#46; 2014&#59;105&#58;434&#46;</p>"
      ]
    ]
    "bibliografia" => array:2 [
      "titulo" => "References"
      "seccion" => array:1 [
        0 => array:2 [
          "identificador" => "bibs0005"
          "bibliografiaReferencia" => array:5 [
            0 => array:3 [
              "identificador" => "bib0005"
              "etiqueta" => "1"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Melanoma of unknown primary site&#58; Presentation&#44; treatment&#44; and prognosis-a single institution study"
                      "autores" => array:1 [
                        0 => array:3 [
                          "colaboracion" => "University of Pennsylvania Pigmented Lesion Study Group"
                          "etal" => true
                          "autores" => array:6 [
                            0 => "K&#46;K&#46; Anbari"
                            1 => "L&#46;M&#46; Schuchter"
                            2 => "L&#46;P&#46; Bucky"
                            3 => "R&#46; Mick"
                            4 => "M&#46; Synnestvedt"
                            5 => "D&#46; Guerry"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Cancer"
                        "fecha" => "1997"
                        "volumen" => "79"
                        "paginaInicial" => "1816"
                        "paginaFinal" => "1821"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9129001"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            1 => array:3 [
              "identificador" => "bib0010"
              "etiqueta" => "2"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Metastatic melanoma of unknown primary origin shows prognostic similarities to regional metastatic melanoma&#58; Recommendations for initial staging examinations"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "B&#46; Schlagenhauff"
                            1 => "W&#46; Stroebel"
                            2 => "U&#46; Ellwanger"
                            3 => "F&#46; Meier"
                            4 => "C&#46; Zimmermann"
                            5 => "H&#46; Breuninger"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Cancer"
                        "fecha" => "1997"
                        "volumen" => "80"
                        "paginaInicial" => "60"
                        "paginaFinal" => "65"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9210709"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            2 => array:3 [
              "identificador" => "bib0015"
              "etiqueta" => "3"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Improved survival after lymphadenectomy for nodal metastasis from unknown primary melanoma"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "C&#46;C&#46; Lee"
                            1 => "M&#46;B&#46; Faries"
                            2 => "L&#46;A&#46; Wanek"
                            3 => "D&#46;L&#46; Morton"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1200/JCO.2007.14.0285"
                      "Revista" => array:6 [
                        "tituloSerie" => "J Clin Oncol"
                        "fecha" => "2008"
                        "volumen" => "26"
                        "paginaInicial" => "535"
                        "paginaFinal" => "541"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/18235114"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            3 => array:3 [
              "identificador" => "bib0020"
              "etiqueta" => "4"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Melanoma of unknown primary is correctly classified by the AJCC melanoma classification from 2009"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "A&#46;F&#46; Pfeil"
                            1 => "U&#46; Leiter"
                            2 => "P&#46;G&#46; Buettner"
                            3 => "T&#46;K&#46; Eigentler"
                            4 => "D&#46; Weide"
                            5 => "F&#46; Meier"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1097/CMR.0b013e32834577ec"
                      "Revista" => array:6 [
                        "tituloSerie" => "Melanoma Res"
                        "fecha" => "2011"
                        "volumen" => "21"
                        "paginaInicial" => "228"
                        "paginaFinal" => "234"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/21502902"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            4 => array:3 [
              "identificador" => "bib0025"
              "etiqueta" => "5"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Solitary dermal melanoma&#58; Beginning or end of the metastatic process"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "C&#46;C&#46; Lee"
                            1 => "M&#46;B&#46; Faries"
                            2 => "X&#46; Ye"
                            3 => "D&#46;L&#46; Morton"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1245/s10434-008-0272-9"
                      "Revista" => array:6 [
                        "tituloSerie" => "Ann Surg Oncol"
                        "fecha" => "2009"
                        "volumen" => "16"
                        "paginaInicial" => "578"
                        "paginaFinal" => "584"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/19130137"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
          ]
        ]
      ]
    ]
  ]
  "idiomaDefecto" => "en"
  "url" => "/15782190/0000010500000004/v1_201404301027/S1578219014000948/v1_201404301027/en/main.assets"
  "Apartado" => array:4 [
    "identificador" => "6208"
    "tipo" => "SECCION"
    "en" => array:2 [
      "titulo" => "Letters to the Editor"
      "idiomaDefecto" => true
    ]
    "idiomaDefecto" => "en"
  ]
  "PDF" => "https://static.elsevier.es/multimedia/15782190/0000010500000004/v1_201404301027/S1578219014000948/v1_201404301027/en/main.pdf?idApp=UINPBA000044&text.app=https://actasdermo.org/"
  "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219014000948?idApp=UINPBA000044"
]
Compartir
Información de la revista

Estadísticas

Siga este enlace para acceder al texto completo del artículo

Letter to the Editor
Response to “Stage IIIC Solitary Dermal Melanoma”
Réplica a «Melanoma dérmico solitario y estadio IIIC»
M. González de Arriba
Servicio de Dermatología, Hospital Clínico Universitario de Salamanca, Salamanca, Spain
Leído
4746
Veces
se ha leído el artículo
1661
Total PDF
3085
Total HTML
Compartir estadísticas
 array:23 [
  "pii" => "S1578219014000948"
  "issn" => "15782190"
  "doi" => "10.1016/j.adengl.2014.02.001"
  "estado" => "S300"
  "fechaPublicacion" => "2014-05-01"
  "aid" => "953"
  "copyright" => "Elsevier Espa&#241;a&#44; S&#46;L&#46; and AEDV"
  "copyrightAnyo" => "2014"
  "documento" => "simple-article"
  "crossmark" => 0
  "subdocumento" => "cor"
  "cita" => "Actas Dermosifiliogr. 2014;105:434"
  "abierto" => array:3 [
    "ES" => true
    "ES2" => true
    "LATM" => true
  ]
  "gratuito" => true
  "lecturas" => array:2 [
    "total" => 1277
    "formatos" => array:3 [
      "EPUB" => 41
      "HTML" => 925
      "PDF" => 311
    ]
  ]
  "Traduccion" => array:1 [
    "es" => array:19 [
      "pii" => "S0001731014000295"
      "issn" => "00017310"
      "doi" => "10.1016/j.ad.2014.02.001"
      "estado" => "S300"
      "fechaPublicacion" => "2014-05-01"
      "aid" => "953"
      "copyright" => "Elsevier Espa&#241;a&#44; S&#46;L&#46; y AEDV"
      "documento" => "simple-article"
      "crossmark" => 0
      "subdocumento" => "cor"
      "cita" => "Actas Dermosifiliogr. 2014;105:434"
      "abierto" => array:3 [
        "ES" => true
        "ES2" => true
        "LATM" => true
      ]
      "gratuito" => true
      "lecturas" => array:2 [
        "total" => 1262
        "formatos" => array:3 [
          "EPUB" => 2
          "HTML" => 966
          "PDF" => 294
        ]
      ]
      "es" => array:10 [
        "idiomaDefecto" => true
        "cabecera" => "<span class="elsevierStyleTextfn">Carta al Director</span>"
        "titulo" => "R&#233;plica a &#171;Melanoma d&#233;rmico solitario y estadio IIIC&#187;"
        "tienePdf" => "es"
        "tieneTextoCompleto" => "es"
        "paginas" => array:1 [
          0 => array:1 [
            "paginaInicial" => "434"
          ]
        ]
        "titulosAlternativos" => array:1 [
          "en" => array:1 [
            "titulo" => "Response to &#8220;Stage IIIC Solitary Dermal Melanoma&#8221;"
          ]
        ]
        "contieneTextoCompleto" => array:1 [
          "es" => true
        ]
        "contienePdf" => array:1 [
          "es" => true
        ]
        "autores" => array:1 [
          0 => array:2 [
            "autoresLista" => "M&#46; Gonz&#225;lez de Arriba"
            "autores" => array:1 [
              0 => array:2 [
                "nombre" => "M&#46;"
                "apellidos" => "Gonz&#225;lez de Arriba"
              ]
            ]
          ]
        ]
      ]
      "idiomaDefecto" => "es"
      "Traduccion" => array:1 [
        "en" => array:9 [
          "pii" => "S1578219014000948"
          "doi" => "10.1016/j.adengl.2014.02.001"
          "estado" => "S300"
          "subdocumento" => ""
          "abierto" => array:3 [
            "ES" => true
            "ES2" => true
            "LATM" => true
          ]
          "gratuito" => true
          "lecturas" => array:1 [
            "total" => 0
          ]
          "idiomaDefecto" => "en"
          "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219014000948?idApp=UINPBA000044"
        ]
      ]
      "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0001731014000295?idApp=UINPBA000044"
      "url" => "/00017310/0000010500000004/v1_201404301030/S0001731014000295/v1_201404301030/es/main.assets"
    ]
  ]
  "itemAnterior" => array:19 [
    "pii" => "S1578219014000936"
    "issn" => "15782190"
    "doi" => "10.1016/j.adengl.2013.12.003"
    "estado" => "S300"
    "fechaPublicacion" => "2014-05-01"
    "aid" => "952"
    "copyright" => "Elsevier Espa&#241;a&#44; S&#46;L&#46; and AEDV"
    "documento" => "simple-article"
    "crossmark" => 0
    "subdocumento" => "cor"
    "cita" => "Actas Dermosifiliogr. 2014;105:433-4"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:2 [
      "total" => 1467
      "formatos" => array:3 [
        "EPUB" => 35
        "HTML" => 1014
        "PDF" => 418
      ]
    ]
    "en" => array:10 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">Letter to the Editor</span>"
      "titulo" => "Stage IIIC Solitary Dermal Melanoma"
      "tienePdf" => "en"
      "tieneTextoCompleto" => "en"
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "433"
          "paginaFinal" => "434"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "es" => array:1 [
          "titulo" => "Melanoma d&#233;rmico solitario y estadio IIIC"
        ]
      ]
      "contieneTextoCompleto" => array:1 [
        "en" => true
      ]
      "contienePdf" => array:1 [
        "en" => true
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "E&#46; Piqu&#233;-Duran"
          "autores" => array:1 [
            0 => array:2 [
              "nombre" => "E&#46;"
              "apellidos" => "Piqu&#233;-Duran"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "en"
    "Traduccion" => array:1 [
      "es" => array:9 [
        "pii" => "S0001731014000283"
        "doi" => "10.1016/j.ad.2013.12.012"
        "estado" => "S300"
        "subdocumento" => ""
        "abierto" => array:3 [
          "ES" => true
          "ES2" => true
          "LATM" => true
        ]
        "gratuito" => true
        "lecturas" => array:1 [
          "total" => 0
        ]
        "idiomaDefecto" => "es"
        "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0001731014000283?idApp=UINPBA000044"
      ]
    ]
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219014000936?idApp=UINPBA000044"
    "url" => "/15782190/0000010500000004/v1_201404301027/S1578219014000936/v1_201404301027/en/main.assets"
  ]
  "en" => array:13 [
    "idiomaDefecto" => true
    "cabecera" => "<span class="elsevierStyleTextfn">Letter to the Editor</span>"
    "titulo" => "Response to &#8220;Stage IIIC Solitary Dermal Melanoma&#8221;"
    "tieneTextoCompleto" => true
    "saludo" => "To the Editor&#58;"
    "paginas" => array:1 [
      0 => array:1 [
        "paginaInicial" => "434"
      ]
    ]
    "autores" => array:1 [
      0 => array:3 [
        "autoresLista" => "M&#46; Gonz&#225;lez de Arriba"
        "autores" => array:1 [
          0 => array:3 [
            "nombre" => "M&#46;"
            "apellidos" => "Gonz&#225;lez de Arriba"
            "email" => array:1 [
              0 => "mgdearriba&#64;yahoo&#46;es"
            ]
          ]
        ]
        "afiliaciones" => array:1 [
          0 => array:2 [
            "entidad" => "Servicio de Dermatolog&#237;a&#44; Hospital Cl&#237;nico Universitario de Salamanca&#44; Salamanca&#44; Spain"
            "identificador" => "aff0005"
          ]
        ]
      ]
    ]
    "titulosAlternativos" => array:1 [
      "es" => array:1 [
        "titulo" => "R&#233;plica a &#171;Melanoma d&#233;rmico solitario y estadio IIIC&#187;"
      ]
    ]
    "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">We thank the author for his interest in our article and find his observations very interesting and enlightening&#46; However&#44; we believe it necessary to make some clarifications&#46;</p><p id="par0010" class="elsevierStylePara elsevierViewall">Even before the publication of the 2009 American Joint Committee on Cancer &#40;AJCC&#41; Staging and Classification&#44; various authors had studied melanoma metastasis from an unknown primary site and concluded that survival in such cases was higher than in known primary cutaneous melanomas and metastases with a similar clinical presentation&#46;</p><p id="par0015" class="elsevierStylePara elsevierViewall">This improved survival has been reported for metastases in the skin and subcutaneous tissue and for local lymph node disease with an unknown primary site&#46; The survival rates are similar to those expected for regional disease &#40;stage III&#41; and nonmetastatic disease&#46;<a class="elsevierStyleCrossRefs" href="#bib0005"><span class="elsevierStyleSup">1&#8211;3</span></a></p><p id="par0020" class="elsevierStylePara elsevierViewall">In the latest AJCC classification&#44; single skin or subcutaneous metastases are considered to be satellite or in-transit metastases&#44; while metastases in the lymph nodes are considered to be regional&#46; In both cases they are categorized as stage III and are therefore associated with higher survival rates&#46;<a class="elsevierStyleCrossRef" href="#bib0020"><span class="elsevierStyleSup">4</span></a></p><p id="par0025" class="elsevierStylePara elsevierViewall">This classification&#44; however&#44; is based only on the observation of better survival in such cases and no consideration is given to the origin of these cutaneous or subcutaneous lesions classified as satellite or in-transit &#40;and therefore metastatic&#41; lesions&#46;</p><p id="par0030" class="elsevierStylePara elsevierViewall">We are interested in the fact that these lesions might also have a primary origin&#44; as this would have new implications for the management of patients beyond a mere classification determining survival and prognosis&#46; As reported by Lee et al&#46;&#44;<a class="elsevierStyleCrossRef" href="#bib0025"><span class="elsevierStyleSup">5</span></a> 23&#37; of patients with solitary dermal melanoma &#40;SDM&#41; may have nodal disease at the time of diagnosis or later and would therefore benefit from sentinel node biopsy and&#44; if indicated&#44; lymphadenectomy&#46; It is noteworthy that sentinel node biopsy would not be indicated if the disease was already considered to be metastatic&#44; although lymphadenectomy might be an option if there is nodal involvement following on from an in-transit metastasis&#46;</p><p id="par0035" class="elsevierStylePara elsevierViewall">Given the different potential origins of a single focus of melanoma in the dermis or subcutaneous tissue&#44; we agree that a diagnosis of primary dermal melanoma is just one option when faced with SDM&#46;</p></span>"
    "pdfFichero" => "main.pdf"
    "tienePdf" => true
    "NotaPie" => array:1 [
      0 => array:2 [
        "etiqueta" => "&#9734;"
        "nota" => "<p class="elsevierStyleNotepara" id="npar0005">Please cite this article as&#58; Gonz&#225;lez de Arriba M&#46; R&#233;plica a &#171;Melanoma d&#233;rmico solitario y estadio IIIC&#187;&#46; Actas Dermosifiliogr&#46; 2014&#59;105&#58;434&#46;</p>"
      ]
    ]
    "bibliografia" => array:2 [
      "titulo" => "References"
      "seccion" => array:1 [
        0 => array:2 [
          "identificador" => "bibs0005"
          "bibliografiaReferencia" => array:5 [
            0 => array:3 [
              "identificador" => "bib0005"
              "etiqueta" => "1"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Melanoma of unknown primary site&#58; Presentation&#44; treatment&#44; and prognosis-a single institution study"
                      "autores" => array:1 [
                        0 => array:3 [
                          "colaboracion" => "University of Pennsylvania Pigmented Lesion Study Group"
                          "etal" => true
                          "autores" => array:6 [
                            0 => "K&#46;K&#46; Anbari"
                            1 => "L&#46;M&#46; Schuchter"
                            2 => "L&#46;P&#46; Bucky"
                            3 => "R&#46; Mick"
                            4 => "M&#46; Synnestvedt"
                            5 => "D&#46; Guerry"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Cancer"
                        "fecha" => "1997"
                        "volumen" => "79"
                        "paginaInicial" => "1816"
                        "paginaFinal" => "1821"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9129001"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            1 => array:3 [
              "identificador" => "bib0010"
              "etiqueta" => "2"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Metastatic melanoma of unknown primary origin shows prognostic similarities to regional metastatic melanoma&#58; Recommendations for initial staging examinations"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "B&#46; Schlagenhauff"
                            1 => "W&#46; Stroebel"
                            2 => "U&#46; Ellwanger"
                            3 => "F&#46; Meier"
                            4 => "C&#46; Zimmermann"
                            5 => "H&#46; Breuninger"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Cancer"
                        "fecha" => "1997"
                        "volumen" => "80"
                        "paginaInicial" => "60"
                        "paginaFinal" => "65"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9210709"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            2 => array:3 [
              "identificador" => "bib0015"
              "etiqueta" => "3"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Improved survival after lymphadenectomy for nodal metastasis from unknown primary melanoma"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "C&#46;C&#46; Lee"
                            1 => "M&#46;B&#46; Faries"
                            2 => "L&#46;A&#46; Wanek"
                            3 => "D&#46;L&#46; Morton"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1200/JCO.2007.14.0285"
                      "Revista" => array:6 [
                        "tituloSerie" => "J Clin Oncol"
                        "fecha" => "2008"
                        "volumen" => "26"
                        "paginaInicial" => "535"
                        "paginaFinal" => "541"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/18235114"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            3 => array:3 [
              "identificador" => "bib0020"
              "etiqueta" => "4"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Melanoma of unknown primary is correctly classified by the AJCC melanoma classification from 2009"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "A&#46;F&#46; Pfeil"
                            1 => "U&#46; Leiter"
                            2 => "P&#46;G&#46; Buettner"
                            3 => "T&#46;K&#46; Eigentler"
                            4 => "D&#46; Weide"
                            5 => "F&#46; Meier"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1097/CMR.0b013e32834577ec"
                      "Revista" => array:6 [
                        "tituloSerie" => "Melanoma Res"
                        "fecha" => "2011"
                        "volumen" => "21"
                        "paginaInicial" => "228"
                        "paginaFinal" => "234"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/21502902"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            4 => array:3 [
              "identificador" => "bib0025"
              "etiqueta" => "5"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Solitary dermal melanoma&#58; Beginning or end of the metastatic process"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "C&#46;C&#46; Lee"
                            1 => "M&#46;B&#46; Faries"
                            2 => "X&#46; Ye"
                            3 => "D&#46;L&#46; Morton"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1245/s10434-008-0272-9"
                      "Revista" => array:6 [
                        "tituloSerie" => "Ann Surg Oncol"
                        "fecha" => "2009"
                        "volumen" => "16"
                        "paginaInicial" => "578"
                        "paginaFinal" => "584"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/19130137"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
          ]
        ]
      ]
    ]
  ]
  "idiomaDefecto" => "en"
  "url" => "/15782190/0000010500000004/v1_201404301027/S1578219014000948/v1_201404301027/en/main.assets"
  "Apartado" => array:4 [
    "identificador" => "6208"
    "tipo" => "SECCION"
    "en" => array:2 [
      "titulo" => "Letters to the Editor"
      "idiomaDefecto" => true
    ]
    "idiomaDefecto" => "en"
  ]
  "PDF" => "https://static.elsevier.es/multimedia/15782190/0000010500000004/v1_201404301027/S1578219014000948/v1_201404301027/en/main.pdf?idApp=UINPBA000044&text.app=https://actasdermo.org/"
  "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219014000948?idApp=UINPBA000044"
]
Información del artículo
ISSN: 15782190
Idioma original: Inglés
Datos actualizados diariamente
año/Mes Html Pdf Total
2024 Noviembre 9 11 20
2024 Octubre 62 38 100
2024 Septiembre 74 23 97
2024 Agosto 96 47 143
2024 Julio 72 30 102
2024 Junio 68 31 99
2024 Mayo 47 27 74
2024 Abril 49 20 69
2024 Marzo 52 26 78
2024 Febrero 46 29 75
2024 Enero 47 29 76
2023 Diciembre 39 26 65
2023 Noviembre 39 26 65
2023 Octubre 60 10 70
2023 Septiembre 56 22 78
2023 Agosto 46 25 71
2023 Julio 54 37 91
2023 Junio 31 19 50
2023 Mayo 42 21 63
2023 Abril 49 22 71
2023 Marzo 39 18 57
2023 Febrero 40 18 58
2023 Enero 32 22 54
2022 Diciembre 34 28 62
2022 Noviembre 23 25 48
2022 Octubre 26 17 43
2022 Septiembre 26 29 55
2022 Agosto 18 24 42
2022 Julio 25 31 56
2022 Junio 19 24 43
2022 Mayo 25 25 50
2022 Abril 31 32 63
2022 Marzo 37 37 74
2022 Febrero 20 27 47
2022 Enero 38 30 68
2021 Diciembre 22 34 56
2021 Noviembre 42 46 88
2021 Octubre 34 36 70
2021 Septiembre 16 32 48
2021 Agosto 23 26 49
2021 Julio 17 25 42
2021 Junio 33 23 56
2021 Mayo 44 35 79
2021 Abril 105 35 140
2021 Marzo 65 5 70
2021 Febrero 48 19 67
2021 Enero 25 17 42
2020 Diciembre 26 10 36
2020 Noviembre 7 5 12
2020 Octubre 21 7 28
2020 Septiembre 28 16 44
2020 Agosto 20 9 29
2020 Julio 17 3 20
2020 Junio 30 20 50
2020 Mayo 20 17 37
2020 Abril 25 9 34
2020 Marzo 18 15 33
2020 Febrero 4 0 4
2020 Enero 0 2 2
2019 Diciembre 4 4 8
2019 Septiembre 4 2 6
2019 Agosto 0 6 6
2019 Julio 0 14 14
2019 Junio 2 18 20
2019 Mayo 0 63 63
2019 Abril 1 12 13
2019 Marzo 2 12 14
2019 Febrero 0 3 3
2019 Enero 1 0 1
2018 Diciembre 2 8 10
2018 Noviembre 0 2 2
2018 Octubre 2 0 2
2018 Septiembre 4 0 4
2018 Julio 0 1 1
2018 Mayo 0 1 1
2018 Abril 0 2 2
2018 Marzo 0 1 1
2018 Febrero 22 1 23
2018 Enero 21 5 26
2017 Diciembre 38 9 47
2017 Noviembre 24 0 24
2017 Octubre 26 5 31
2017 Septiembre 26 4 30
2017 Agosto 37 10 47
2017 Julio 41 8 49
2017 Junio 40 6 46
2017 Mayo 36 3 39
2017 Abril 26 4 30
2017 Marzo 31 6 37
2017 Febrero 23 3 26
2017 Enero 14 2 16
2016 Diciembre 28 7 35
2016 Noviembre 39 1 40
2016 Octubre 38 19 57
2016 Septiembre 30 2 32
2016 Agosto 26 1 27
2016 Julio 29 2 31
2016 Junio 9 0 9
2016 Mayo 5 4 9
2016 Abril 5 0 5
2016 Marzo 6 1 7
2016 Febrero 16 1 17
2016 Enero 6 1 7
2015 Diciembre 4 0 4
2015 Noviembre 7 0 7
2015 Octubre 5 2 7
2015 Septiembre 1 0 1
2015 Agosto 8 2 10
2015 Julio 30 1 31
2015 Junio 18 2 20
2015 Mayo 33 2 35
2015 Abril 21 2 23
2015 Marzo 25 2 27
2015 Febrero 8 0 8
2015 Enero 9 2 11
2014 Diciembre 18 3 21
2014 Noviembre 15 9 24
2014 Octubre 17 7 24
2014 Septiembre 6 4 10
2014 Agosto 8 5 13
2014 Julio 6 6 12
2014 Junio 10 3 13
2014 Mayo 11 3 14
Mostrar todo

Siga este enlace para acceder al texto completo del artículo

Idiomas
Actas Dermo-Sifiliográficas
es en

¿Es usted profesional sanitario apto para prescribir o dispensar medicamentos?

Are you a health professional able to prescribe or dispense drugs?