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providing us as dermatologists&#44; in an entertaining way&#44; a historical review of the treatments used in our specialty over the decades&#46;</p><p id="par0025" class="elsevierStylePara elsevierViewall">The term <span class="elsevierStyleItalic">marketing</span> refers to the whole process of promoting and selling a product from the moment it is created until it is purchased&#46; This process involves many aspects and it is on these&#44; to a greater or lesser extent&#44; that the commercial success or failure of the product depends&#46; Advertising is one such factor&#46;<a class="elsevierStyleCrossRef" href="#bib0025"><span class="elsevierStyleSup">5</span></a></p><p id="par0030" class="elsevierStylePara elsevierViewall">An advertisement is a communication intended to convince the customer of the worth of a product&#46;<a class="elsevierStyleCrossRef" href="#bib0030"><span class="elsevierStyleSup">6</span></a> If we were to apply this definition to the advertisements that appear in our journal&#44; we could say that it is advertising targeting dermatologists through the medium of a medical journal&#46;</p></span><span id="sec0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0030">Advertising Between 1909 and 1936</span><p id="par0035" class="elsevierStylePara elsevierViewall">From the start of the publication of <span class="elsevierStyleSmallCaps">Actas Dermosifiliogr&#225;ficas</span> in 1909&#44; advertising was present in the journal and the revenue appeared in the society&#39;s books under the heading &#8220;accounts receivable&#46;&#8221; Income from this source&#44; which started out as 260 pesetas&#44; had risen by 1926 to 4430 pesetas&#46;</p><p id="par0040" class="elsevierStylePara elsevierViewall">Initially&#44; the list of advertisers was rather short and most of the advertisers were private individuals who provided a postal address to which physicians could apply for the products advertised rather than pharmaceutical companies as we know them today&#46; Later&#44; the journal started to publish a list of advertisers&#44; which included some pharmaceutical companies&#44; their business addresses&#44; and the products they sold&#46;</p><p id="par0045" class="elsevierStylePara elsevierViewall">In 1932&#44; the Academy&#39;s Board of Directors decided to modify the advertising rates and created a new scale with different prices for different types of advertisements depending on where they appeared in the journal &#40;front cover&#44; full page&#44; set in text&#44; display format&#44; etc&#46;&#41; &#40;<a class="elsevierStyleCrossRef" href="#fig0005">Fig&#46; 1</a>&#41;&#46;</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><p id="par0050" class="elsevierStylePara elsevierViewall">In addition to the new scale for advertising&#44; a second rate sheet was produced &#40;called &#8220;the 2nd&#8221;&#41;&#44; which listed the prices for loose inserts &#40;blue or yellow sheets&#41;&#46; Very few of these inserts survived when the journals were bound into the volumes now archived in the Academy&#39;s library&#46;</p><p id="par0055" class="elsevierStylePara elsevierViewall">The oldest advertisement that appears in the archive refers to &#8220;Iodargirum&#8221;&#44; a preparation of iodo-cacodylate of mercury sold by the pharmacist Mr&#46; Llopis &#40;<a class="elsevierStyleCrossRef" href="#fig0010">Fig&#46; 2</a>&#41;&#46;</p><elsevierMultimedia ident="fig0010"></elsevierMultimedia><p id="par0060" class="elsevierStylePara elsevierViewall">Our review of the advertising published during this period reveals that the products most often advertised were those related to the treatment of sexually transmitted diseases&#44; a finding that agrees with the observation of another author&#46;<a class="elsevierStyleCrossRef" href="#bib0020"><span class="elsevierStyleSup">4</span></a> This predominance is logical when we take into account that the diagnosis and treatment of venereal diseases constituted a large part of the professional activity of dermatologists in the first third of the last century&#46;<a class="elsevierStyleCrossRef" href="#bib0035"><span class="elsevierStyleSup">7</span></a> Advertisements can be found for arsenic compounds&#44; different bismuth compounds for parenteral use&#44; and drugs that combined bismuth&#44; mercury&#44; and arsenic&#46; Also common were advertisements for oral and topical arsenic preparations &#40;<a class="elsevierStyleCrossRef" href="#fig0015">Fig&#46; 3</a>&#41;&#46;</p><elsevierMultimedia ident="fig0015"></elsevierMultimedia><p id="par0065" class="elsevierStylePara elsevierViewall">Before the Civil War&#44; some pharmaceutical representatives in Spain&#44; such as Robert Soyer&#44; offered dermatologists a wide variety of products for the treatment of patients with tuberculosis&#44; syphilis&#44; and leprosy&#46;</p><p id="par0070" class="elsevierStylePara elsevierViewall">Given its importance in dermatological practice&#44; topical therapy deserves special mention&#46;</p><p id="par0075" class="elsevierStylePara elsevierViewall">The topical armamentarium in this era was dominated by a series of products called the <span class="elsevierStyleItalic">Dermosas</span> &#40;<a class="elsevierStyleCrossRef" href="#fig0020">Fig&#46; 4</a>&#41;&#46; 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After application&#44; depending on the case&#44; dressing with Cus&#237;&#8217;s waxed mesh or hydrophilic gauze or cotton was recommended&#46;</p><elsevierMultimedia ident="fig0020"></elsevierMultimedia></span><span id="sec0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0035">The Period Between 1936 and 1939</span><p id="par0080" class="elsevierStylePara elsevierViewall">In the closing months of the Spanish Civil War &#40;1936-1939&#41;&#44; advertisements for cosmetics start to appear&#44; including a hair setting lotion called NEOFIX and an advertisement for Perfumer&#237;a GAL S&#46;A&#46; featuring a text clearly influenced by the political context of the time&#46;</p><p id="par0085" class="elsevierStylePara elsevierViewall">Advertisements for the treatment of sexually transmitted diseases continue to predominate&#46; These included&#44; Novarsenobenzol &#40;Billon&#41; and an oral arsenic compound&#44; both sold by the Societ&#233; Parisienne d&#8217;Expansion Chimique &#40;SPECIA&#41;&#8212;a predecessor of the pharmaceutical company Rhone-Poulenc&#8212;who advertised them with the inducement &#8220;included in the standard order of the military health authorities&#46;&#8221;</p><p id="par0090" class="elsevierStylePara elsevierViewall">The same period saw the emergence of the arsenobenzenes&#44; manufactured in Spain by the F&#225;brica Espa&#241;ola de Productos Qu&#237;micos y Farmac&#233;uticos&#44; S&#46;A&#46; &#40;FAES&#41; &#40;<a class="elsevierStyleCrossRef" href="#fig0025">Fig&#46; 5</a>&#41; and in Italy by the Istituto Chemioterapico Italiano &#40;ICI&#41; in Florence&#46;</p><elsevierMultimedia ident="fig0025"></elsevierMultimedia><p id="par0095" class="elsevierStylePara elsevierViewall">Laboratorios C&#225;ntabro de Santander advertised Hiposulfin&#44; a product based on sodium thiosulfate that was used as a solvent in the treatment of patients intolerant to arsenobenzols&#46; The company made the point in its advertisements that the product was &#8220;as cheap as double-distilled water&#46;&#8221;</p><p id="par0100" class="elsevierStylePara elsevierViewall">Laboratorios Gil in Seville&#8212;a precursor of Farmacia &#8220;El Globo&#8221;&#8212;promoted Espirogil&#44; a double iodide of bismuth and quinine&#44; with the advertised advantage that the treatment was painless&#44; although they added the recommendation &#8220;soak in hot water to facilitate injection&#46;&#8221;</p><p id="par0105" class="elsevierStylePara elsevierViewall">Advertisement of bismuth-based compounds proliferated&#44; with an interesting note on one from Laboratorios Pons a company located in the town of Lerida &#40;present-day Lleida&#41; indicating that the company has temporarily relocated due to the war when citing as an address &#8220;accidentally&#58; Hotel Biarritz - San Sebastian&#41;&#46;</p><p id="par0110" class="elsevierStylePara elsevierViewall">Another advertisement promotes Santal Monal imported directly from Paris for the treatment of gonorrhea &#40;<a class="elsevierStyleCrossRef" href="#fig0030">Fig&#46; 6</a>&#41;&#46; This product was based on methylene blue formulated as a solution for intraurethral injection&#46;</p><elsevierMultimedia ident="fig0030"></elsevierMultimedia><p id="par0115" class="elsevierStylePara elsevierViewall">The soft chancre could be treated with Dmelcos&#44; a stabilized vaccine with a concentration of 225 million of Ducrey bacilli per cm<span class="elsevierStyleSup">3</span>&#46;</p><p id="par0120" class="elsevierStylePara elsevierViewall">At this time new topical products appear&#44; particularly antibacterials&#44; such as &#8220;Dermocolesterina&#8221; produced by Mazuelos of Osuna&#44; &#8220;B&#225;lsamo Angelical&#8221; &#40;heavenly balm&#41; sold by Mart&#237;n Nu&#241;ez of Zamora&#44; and &#8220;Fomentobiol&#8221; by Serva&#46;</p><p id="par0125" class="elsevierStylePara elsevierViewall">In short&#44; the illustrated advertisements of the time reflect the start of a growing relationship between the pharmaceutical industry and scientific journals&#44; which serve as a channel for marketing their products to professionals&#46; This relationship&#44; which still continues today&#44; has become a mainstay both for the industry and for the economic viability of medical journals&#46; The products advertised&#44; almost all outdated today&#44; also clearly reflect the therapeutic developments of the time&#44; when they represented a qualitative leap in treatment&#46; Finally&#44; the advertising provides a window onto the social and political conditions of the era and the role of dermatologists&#44; who mainly devoted their time to the management of sexually transmitted diseases&#46;</p></span><span id="sec0020" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0040">Conflicts of Interest</span><p id="par0130" class="elsevierStylePara elsevierViewall">The authors declare that they have no conflicts of interest&#46;</p></span></span>"
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History and Humanities in Dermatology
Advertising in Actas Dermosifiliográficas, 1909–1939
Publicidad en Actas Dermosifiliográficas (1909-1939)
R.M. Díaz-Díaz
Sección de Dermatología, Hospital Universitario Infanta Sofía, San Sebastián de los Reyes, Madrid, Spain
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providing us as dermatologists&#44; in an entertaining way&#44; a historical review of the treatments used in our specialty over the decades&#46;</p><p id="par0025" class="elsevierStylePara elsevierViewall">The term <span class="elsevierStyleItalic">marketing</span> refers to the whole process of promoting and selling a product from the moment it is created until it is purchased&#46; This process involves many aspects and it is on these&#44; to a greater or lesser extent&#44; that the commercial success or failure of the product depends&#46; Advertising is one such factor&#46;<a class="elsevierStyleCrossRef" href="#bib0025"><span class="elsevierStyleSup">5</span></a></p><p id="par0030" class="elsevierStylePara elsevierViewall">An advertisement is a communication intended to convince the customer of the worth of a product&#46;<a class="elsevierStyleCrossRef" href="#bib0030"><span class="elsevierStyleSup">6</span></a> If we were to apply this definition to the advertisements that appear in our journal&#44; we could say that it is advertising targeting dermatologists through the medium of a medical journal&#46;</p></span><span id="sec0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0030">Advertising Between 1909 and 1936</span><p id="par0035" class="elsevierStylePara elsevierViewall">From the start of the publication of <span class="elsevierStyleSmallCaps">Actas Dermosifiliogr&#225;ficas</span> in 1909&#44; advertising was present in the journal and the revenue appeared in the society&#39;s books under the heading &#8220;accounts receivable&#46;&#8221; Income from this source&#44; which started out as 260 pesetas&#44; had risen by 1926 to 4430 pesetas&#46;</p><p id="par0040" class="elsevierStylePara elsevierViewall">Initially&#44; the list of advertisers was rather short and most of the advertisers were private individuals who provided a postal address to which physicians could apply for the products advertised rather than pharmaceutical companies as we know them today&#46; Later&#44; the journal started to publish a list of advertisers&#44; which included some pharmaceutical companies&#44; their business addresses&#44; and the products they sold&#46;</p><p id="par0045" class="elsevierStylePara elsevierViewall">In 1932&#44; the Academy&#39;s Board of Directors decided to modify the advertising rates and created a new scale with different prices for different types of advertisements depending on where they appeared in the journal &#40;front cover&#44; full page&#44; set in text&#44; display format&#44; etc&#46;&#41; &#40;<a class="elsevierStyleCrossRef" href="#fig0005">Fig&#46; 1</a>&#41;&#46;</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><p id="par0050" class="elsevierStylePara elsevierViewall">In addition to the new scale for advertising&#44; a second rate sheet was produced &#40;called &#8220;the 2nd&#8221;&#41;&#44; which listed the prices for loose inserts &#40;blue or yellow sheets&#41;&#46; Very few of these inserts survived when the journals were bound into the volumes now archived in the Academy&#39;s library&#46;</p><p id="par0055" class="elsevierStylePara elsevierViewall">The oldest advertisement that appears in the archive refers to &#8220;Iodargirum&#8221;&#44; 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These were manufactured by a company in northern Spain run by the pharmacist Joaquim Cus&#237; y Fortunet&#44; who founded a family business selling medical products in 1902&#46; Armed with these <span class="elsevierStyleItalic">Dermosas</span>&#44; the dermatologists of the day could try to cure a wide variety of skin conditions&#46; Cus&#237; produced a <span class="elsevierStyleItalic">Dermosa</span> for the treatment of eczema containing Dohi paste&#44; a compound named after Professor Keizo Dohi that comprised a mixture of tar&#44; sulfur&#44; and zinc oxide in a fatty excipient&#46; Pyodermas were treated with the chloramine-based <span class="elsevierStyleItalic">Dermosas</span> Clorazin and Dercusan&#46; Dermatologists also prescribed all-purpose topical treatments that could be used to treat any kind of dermatitis&#46; These included the zinc&#44; oxymercuric&#44; and &#8220;refreshing&#8221; <span class="elsevierStyleItalic">Dermosas</span>&#44; the last of which was a formula devised by Paul Gerson Unna&#46; After application&#44; depending on the case&#44; dressing with Cus&#237;&#8217;s waxed mesh or hydrophilic gauze or cotton was recommended&#46;</p><elsevierMultimedia ident="fig0020"></elsevierMultimedia></span><span id="sec0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0035">The Period Between 1936 and 1939</span><p id="par0080" class="elsevierStylePara elsevierViewall">In the closing months of the Spanish Civil War &#40;1936-1939&#41;&#44; advertisements for cosmetics start to appear&#44; including a hair setting lotion called NEOFIX and an advertisement for Perfumer&#237;a GAL S&#46;A&#46; featuring a text clearly influenced by the political context of the time&#46;</p><p id="par0085" class="elsevierStylePara elsevierViewall">Advertisements for the treatment of sexually transmitted diseases continue to predominate&#46; These included&#44; Novarsenobenzol &#40;Billon&#41; and an oral arsenic compound&#44; both sold by the Societ&#233; Parisienne d&#8217;Expansion Chimique &#40;SPECIA&#41;&#8212;a predecessor of the pharmaceutical company Rhone-Poulenc&#8212;who advertised them with the inducement &#8220;included in the standard order of the military health authorities&#46;&#8221;</p><p id="par0090" class="elsevierStylePara elsevierViewall">The same period saw the emergence of the arsenobenzenes&#44; manufactured in Spain by the F&#225;brica Espa&#241;ola de Productos Qu&#237;micos y Farmac&#233;uticos&#44; S&#46;A&#46; &#40;FAES&#41; &#40;<a class="elsevierStyleCrossRef" href="#fig0025">Fig&#46; 5</a>&#41; and in Italy by the Istituto Chemioterapico Italiano &#40;ICI&#41; in Florence&#46;</p><elsevierMultimedia ident="fig0025"></elsevierMultimedia><p id="par0095" class="elsevierStylePara elsevierViewall">Laboratorios C&#225;ntabro de Santander advertised Hiposulfin&#44; a product based on sodium thiosulfate that was used as a solvent in the treatment of patients intolerant to arsenobenzols&#46; The company made the point in its advertisements that the product was &#8220;as cheap as double-distilled water&#46;&#8221;</p><p id="par0100" class="elsevierStylePara elsevierViewall">Laboratorios Gil in Seville&#8212;a precursor of Farmacia &#8220;El Globo&#8221;&#8212;promoted Espirogil&#44; a double iodide of bismuth and quinine&#44; with the advertised advantage that the treatment was painless&#44; although they added the recommendation &#8220;soak in hot water to facilitate injection&#46;&#8221;</p><p id="par0105" class="elsevierStylePara elsevierViewall">Advertisement of bismuth-based compounds proliferated&#44; with an interesting note on one from Laboratorios Pons a company located in the town of Lerida &#40;present-day Lleida&#41; indicating that the company has temporarily relocated due to the war when citing as an address &#8220;accidentally&#58; Hotel Biarritz - San Sebastian&#41;&#46;</p><p id="par0110" class="elsevierStylePara elsevierViewall">Another advertisement promotes Santal Monal imported directly from Paris for the treatment of gonorrhea &#40;<a class="elsevierStyleCrossRef" href="#fig0030">Fig&#46; 6</a>&#41;&#46; This product was based on methylene blue formulated as a solution for intraurethral injection&#46;</p><elsevierMultimedia ident="fig0030"></elsevierMultimedia><p id="par0115" class="elsevierStylePara elsevierViewall">The soft chancre could be treated with Dmelcos&#44; a stabilized vaccine with a concentration of 225 million of Ducrey bacilli per cm<span class="elsevierStyleSup">3</span>&#46;</p><p id="par0120" class="elsevierStylePara elsevierViewall">At this time new topical products appear&#44; particularly antibacterials&#44; such as &#8220;Dermocolesterina&#8221; produced by Mazuelos of Osuna&#44; &#8220;B&#225;lsamo Angelical&#8221; &#40;heavenly balm&#41; sold by Mart&#237;n Nu&#241;ez of Zamora&#44; and &#8220;Fomentobiol&#8221; by Serva&#46;</p><p id="par0125" class="elsevierStylePara elsevierViewall">In short&#44; the illustrated advertisements of the time reflect the start of a growing relationship between the pharmaceutical industry and scientific journals&#44; which serve as a channel for marketing their products to professionals&#46; This relationship&#44; which still continues today&#44; has become a mainstay both for the industry and for the economic viability of medical journals&#46; The products advertised&#44; almost all outdated today&#44; also clearly reflect the therapeutic developments of the time&#44; when they represented a qualitative leap in treatment&#46; Finally&#44; the advertising provides a window onto the social and political conditions of the era and the role of dermatologists&#44; who mainly devoted their time to the management of sexually transmitted diseases&#46;</p></span><span id="sec0020" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0040">Conflicts of Interest</span><p id="par0130" class="elsevierStylePara elsevierViewall">The authors declare that they have no conflicts of interest&#46;</p></span></span>"
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          "titulo" => "Introduction"
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          "identificador" => "sec0010"
          "titulo" => "Advertising Between 1909 and 1936"
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    "resumen" => array:2 [
      "en" => array:2 [
        "titulo" => "Abstract"
        "resumen" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">We review advertisements published in the journal <span class="elsevierStyleSmallCaps">Actas Dermosifiliogr&#225;ficas</span> between 1909 and 1939&#46; Treatments for sexually transmitted diseases were advertised with particular frequency&#44; and they offer a case in point that exemplifies the close relationship between the pharmaceutical industry and medical journals&#46;</p>"
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        "resumen" => "<p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Aportamos algunos datos acerca de los anuncios publicados en la revista <span class="elsevierStyleSmallCaps">Actas Dermosifiliogr&#225;ficas</span> durante el periodo 1909-1939&#46; Destacan los anuncios relacionados con el tratamiento de las enfermedades de transmisi&#243;n sexual&#46; Son un ejemplo de la estrecha relaci&#243;n existente entre la industria farmac&#233;utica y las revistas m&#233;dicas&#46;</p>"
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          "en" => "<p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">Advertising rates for Actas Dermo-Sifiliogr&#225;ficas&#46; 1932&#46;</p>"
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Información del artículo
ISSN: 15782190
Idioma original: Inglés
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2015 Septiembre 5 4 9
2015 Agosto 9 1 10
2015 Julio 34 7 41
2015 Junio 28 4 32
2015 Mayo 34 4 38
2015 Abril 18 3 21
2015 Marzo 23 0 23
2015 Febrero 27 3 30
2015 Enero 18 2 20
2014 Diciembre 24 4 28
2014 Noviembre 9 4 13
2014 Octubre 11 7 18
2014 Septiembre 8 3 11
2014 Agosto 6 4 10
2014 Julio 8 5 13
2014 Junio 12 5 17
2014 Mayo 13 4 17
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Idiomas
Actas Dermo-Sifiliográficas
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¿Es usted profesional sanitario apto para prescribir o dispensar medicamentos?

Are you a health professional able to prescribe or dispense drugs?