CASE AND RESEARCH LETTER
Dermatomyofibroma on the Nape of the Neck: A Report of 2 Pediatric Cases
Dermatomiofibroma en la nuca: descripción de 2 casos en la edad pediátrica
a Servicio de Dermatología, Corporación Sanitaria Parc Taulí, Hospital Universitario Parc Taulí, Universidad Autónoma de Barcelona, Barcelona, Spain
b Servicio de Anatomía Patológica, Corporación Sanitaria Parc Taulí, Hospital Universitario Parc Taulí, Universidad Autónoma de Barcelona, Barcelona, Spain
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Romaní, L. Leal, A. Sáez, J. Luelmo" "autores" => array:4 [ 0 => array:4 [ "nombre" => "J." "apellidos" => "Romaní" "email" => array:1 [ 0 => "jromani@tauli.cat" ] "referencia" => array:2 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] 1 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">¿</span>" "identificador" => "cor0005" ] ] ] 1 => array:3 [ "nombre" => "L." "apellidos" => "Leal" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] ] ] 2 => array:3 [ "nombre" => "A." "apellidos" => "Sáez" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff0010" ] ] ] 3 => array:3 [ "nombre" => "J." "apellidos" => "Luelmo" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] ] ] ] "afiliaciones" => array:2 [ 0 => array:3 [ "entidad" => "Servicio de Dermatología, Corporación Sanitaria Parc Taulí, Hospital Universitario Parc Taulí, Universidad Autónoma de Barcelona, Barcelona, Spain" "etiqueta" => "a" "identificador" => "aff0005" ] 1 => array:3 [ "entidad" => "Servicio de Anatomía Patológica, Corporación Sanitaria Parc Taulí, Hospital Universitario Parc Taulí, Universidad Autónoma de Barcelona, Barcelona, Spain" "etiqueta" => "b" "identificador" => "aff0010" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "⁎" "correspondencia" => "Corresponding author." ] ] ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Dermatomiofibroma en la nuca: descripción de 2 casos en la edad pediátrica" ] ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:7 [ "identificador" => "fig0010" "etiqueta" => "Figure 2" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr2.jpeg" "Alto" => 851 "Ancho" => 1301 "Tamanyo" => 209688 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Histopathology image of the tumor. A, at low magnification (original magnification, ×<span class="elsevierStyleHsp" style=""></span>20) and B, a high magnification (original magnification, ×<span class="elsevierStyleHsp" style=""></span>200) (hematoxylin-eosin).</p>" ] ] ] "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">Dermatomyofibroma is a rare benign tumor of myofibroblastic origin that was initially called plaque fibromatosis in the literature.<a class="elsevierStyleCrossRef" href="#bib0005"><span class="elsevierStyleSup">1</span></a> It is most common in young women, but has occasionally been described in pediatric patients. A recently published review gathered a total of 34 cases in children.<a class="elsevierStyleCrossRef" href="#bib0010"><span class="elsevierStyleSup">2</span></a> We present 2 pediatric cases (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>, A and B) recently diagnosed and treated in our hospital. These cases support the benign nature of the lesion and the tendency of the tumor to arise on the neck.</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><p id="par0010" class="elsevierStylePara elsevierViewall">The first patient was a 5-year-old boy with no past medical history of interest. He was referred to the dermatologist for evaluation of a tumor on the neck (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>A) that his parents had noticed approximately 6 months earlier. There was no reported history of trauma. This asymptomatic lesion was palpable more than visible and it had a maximum diameter of 0.6<span class="elsevierStyleHsp" style=""></span>cm.</p><p id="par0015" class="elsevierStylePara elsevierViewall">A punch biopsy taken from the center of the lesion revealed epidermal hyperplasia with mild hyperpigmentation of the basal layer. The full thickness of the dermis was affected by a proliferation of spindle-shaped cells in a fascicular arrangement, with their axes mainly oriented parallel to the epidermis; the lesion was paucicellular, and no cellular atypia or mitotic figures were observed. The spindle cells had slightly wavy nuclei (<a class="elsevierStyleCrossRef" href="#fig0010">Fig. 2</a>, A and B). No hyaline globules were observed in the cell cytoplasm. Immunohistochemistry was negative for protein s100, smooth muscle actin, muscle specific actin, desmin, Caldesmon, and CD34. Complete excision of the lesion was then performed and histology study reported identical findings.</p><elsevierMultimedia ident="fig0010"></elsevierMultimedia><p id="par0020" class="elsevierStylePara elsevierViewall">The second patient was a 13-year-old boy with no relevant past medical history. He was referred to dermatology for investigation of an asymptomatic erythematous nodule on the neck with a maximum diameter of 1<span class="elsevierStyleHsp" style=""></span>cm (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>B). The lesion had been present for at least 2 years. No history of trauma to the area was reported.</p><p id="par0025" class="elsevierStylePara elsevierViewall">Punch biopsy and subsequent complete excision revealed an epidermis and superficial and mid dermis with no significant alterations, and a proliferation of spindle-shaped cells in the reticular dermis and most superficial part of the subcutaneous cellular tissue. This proliferation, which was paucicellular and showed no cellular atypia, formed bundles running parallel to the epidermis. The lesion presented noninfiltrative growth, surrounding but not eliminating the skin adnexa. Immunohistochemistry showed the cells to be negative for s100, smooth muscle actin, muscle specific actin, desmin, bcl-2, CD34, and CD99. The histology findings were identical to those of the previous case, shown in <a class="elsevierStyleCrossRef" href="#fig0010">Fig. 2</a>, A and B.</p><p id="par0030" class="elsevierStylePara elsevierViewall">Both patients were followed up for 2 years after excision of the tumors and no recurrences were observed.</p><p id="par0035" class="elsevierStylePara elsevierViewall">Dermatomiofibroma is a rare tumor in the pediatric age range. The first description of this tumor was published by Hügel<a class="elsevierStyleCrossRef" href="#bib0005"><span class="elsevierStyleSup">1</span></a> in 1991. It was initially called plaque fibromatosis. The name dermatomyofibroma was proposed by Kamino<a class="elsevierStyleCrossRef" href="#bib0010"><span class="elsevierStyleSup">2</span></a> in 1992. The largest global series was gathered by Mentzel et al.,<a class="elsevierStyleCrossRef" href="#bib0015"><span class="elsevierStyleSup">3</span></a> with a total of 56 patients aged between 3 and 51 years, and there was a female predominance. The main characteristic of the tumor is a proliferation of spindle cells oriented parallel to the surface of the epidermis. Ultrastructural studies and immunophenotyping have shown these cells to be fibroblasts and myofibroblasts. The immunohistochemical profile is very variable, although vimentin is frequently expressed. CD34 expression has been reported in some cases; this can complicate the diagnosis as dermatofibrosarcoma protuberans must then be considered in the differential diagnosis. Immunohistochemistry is useful to orient the pathologist, but the diagnosis is fundamentally morphological. Treatment is surgical, and recurrence is rare after excision with an adequate margin.</p><p id="par0040" class="elsevierStylePara elsevierViewall">Tardío et al.<a class="elsevierStyleCrossRef" href="#bib0020"><span class="elsevierStyleSup">4</span></a> gathered a total of 34 cases in children and 56% of those tumors were found on the neck, as in the 2 patients we describe. A primary characteristic of pediatric dermatomyofibroma therefore appears to be its tendency to arise in the cervical region. In adults, on the other hand, the tumor arises most frequently on the shoulders or proximal region of the limbs and is less common on the neck. The second characteristic is that the tumor predominantly affects boys. In adults, 90% of cases are in women.<a class="elsevierStyleCrossRefs" href="#bib0025"><span class="elsevierStyleSup">5–8</span></a> It has been speculated that the tumor may spontaneously regress in male children at puberty and persist in girls, leading to a higher prevalence in adult women.</p><p id="par0045" class="elsevierStylePara elsevierViewall">The importance of this disease is its differentiation from other tumors formed of spindle cells, such as desmoid tumor and dermatofibrosarcoma protuberans. In addition, other mesenchymal lesions more typical of the pediatric age range, such as fibrous hamartoma of infancy, myofibromatosis, connective tissue nevus, and smooth muscle hamartoma, must be excluded. A guide to the differential diagnosis of these tumors is presented in <a class="elsevierStyleCrossRef" href="#tbl0005">Table 1</a>.</p><elsevierMultimedia ident="tbl0005"></elsevierMultimedia></span>" "pdfFichero" => "main.pdf" "tienePdf" => true "NotaPie" => array:1 [ 0 => array:2 [ "etiqueta" => "☆" "nota" => "<p class="elsevierStyleNotepara" id="npar0005">Please cite this article as: Romaní J, Leal L, Sáez A, Luelmo J. Dermatomiofibroma en la nuca: descripción de 2 casos en la edad pediátrica. Actas Dermosifiliogr. 2014 105:315–317.</p>" ] ] "multimedia" => array:3 [ 0 => array:7 [ "identificador" => "fig0005" "etiqueta" => "Figure 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 1438 "Ancho" => 901 "Tamanyo" => 153622 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Clinical image of the tumors on the neck of patient 1 (A) and of patient 2 (B).</p>" ] ] 1 => array:7 [ "identificador" => "fig0010" "etiqueta" => "Figure 2" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr2.jpeg" "Alto" => 851 "Ancho" => 1301 "Tamanyo" => 209688 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Histopathology image of the tumor. A, at low magnification (original magnification, ×<span class="elsevierStyleHsp" style=""></span>20) and B, a high magnification (original magnification, ×<span class="elsevierStyleHsp" style=""></span>200) (hematoxylin-eosin).</p>" ] ] 2 => array:7 [ "identificador" => "tbl0005" "etiqueta" => "Table 1" "tipo" => "MULTIMEDIATABLA" "mostrarFloat" => true "mostrarDisplay" => false "tabla" => array:1 [ "tablatextoimagen" => array:1 [ 0 => array:2 [ "tabla" => array:1 [ 0 => """ <table border="0" frame="\n \t\t\t\t\tvoid\n \t\t\t\t" class=""><thead title="thead"><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-head\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t" style="border-bottom: 2px solid black"> \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-head\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t" style="border-bottom: 2px solid black">Morphology \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-head\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t" style="border-bottom: 2px solid black">Immunohistochemistry \t\t\t\t\t\t\n \t\t\t\t</td></tr></thead><tbody title="tbody"><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Dermatomyofibroma \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Bundles of cells running parallel to the epidermis. Noninvasive pattern. Increased and fragmented elastic fibers \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Variable. Usually vimentin<span class="elsevierStyleHsp" style=""></span>+ Stains for smooth muscle actin, desmin, factor <span class="elsevierStyleSmallCaps">xiii</span>a, and CD34 occasionally positive \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Dermatofibrosarcoma protuberans \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Storiform pattern, invasion of adnexa and subcutaneous tissue, decreased elastic fibers \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">CD34+ Factor <span class="elsevierStyleSmallCaps">xiii</span>a- \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Desmoid fibromatosis \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Infiltrative tumor in the subcutaneous tissue. Dermis spared. \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Beta-catenin<span class="elsevierStyleHsp" style=""></span>+ Actin<span class="elsevierStyleHsp" style=""></span>+ \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Fibrous hamartoma of infancy \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Oval or stellate mesenchymal cells in a myxoid stroma, mature adipocytes \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Smooth muscle actin<span class="elsevierStyleHsp" style=""></span>+ Calponin<span class="elsevierStyleHsp" style=""></span>+ Some cells: vimentin<span class="elsevierStyleHsp" style=""></span>+ \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Connective tissue nevus \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Paucicellular. Predominance of stroma with compact or sclerotic collagen \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Variable \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Smooth muscle hamartoma \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Disordered fascicles of muscle cells \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Smooth muscle actin<span class="elsevierStyleHsp" style=""></span>+ \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Myofibromatosis \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Multinodular configuration, association with hemangiopericytoid vessels \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Vimentin<span class="elsevierStyleHsp" style=""></span>+ Actin<span class="elsevierStyleHsp" style=""></span>+ \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Hypopigmented blue nevus \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Spindle cells orientated parallel to the epidermis \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">S100+ and other melanocytic markers \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Dermatofibroma \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Storiform pattern, reduced elastic fibers, presence of histiocytes \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Factor <span class="elsevierStyleSmallCaps">xiii</span>a+ \t\t\t\t\t\t\n \t\t\t\t</td></tr></tbody></table> """ ] "imagenFichero" => array:1 [ 0 => "xTab478848.png" ] ] ] ] "descripcion" => array:1 [ "en" => "<p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">Key to the Differential Diagnosis of Mesenchymal Tumors in the Children.</p>" ] ] ] "bibliografia" => array:2 [ "titulo" => "References" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:8 [ 0 => array:3 [ "identificador" => "bib0005" "etiqueta" => "1" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Die plaqueformige dermale fibromatose" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "H. 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| año/Mes | Html | Total | |
|---|---|---|---|
| 2024 Noviembre | 17 | 6 | 23 |
| 2024 Octubre | 106 | 43 | 149 |
| 2024 Septiembre | 112 | 35 | 147 |
| 2024 Agosto | 152 | 71 | 223 |
| 2024 Julio | 112 | 47 | 159 |
| 2024 Junio | 133 | 47 | 180 |
| 2024 Mayo | 126 | 43 | 169 |
| 2024 Abril | 101 | 17 | 118 |
| 2024 Marzo | 102 | 43 | 145 |
| 2024 Febrero | 87 | 48 | 135 |
| 2024 Enero | 93 | 44 | 137 |
| 2023 Diciembre | 86 | 28 | 114 |
| 2023 Noviembre | 94 | 62 | 156 |
| 2023 Octubre | 101 | 31 | 132 |
| 2023 Septiembre | 102 | 46 | 148 |
| 2023 Agosto | 64 | 36 | 100 |
| 2023 Julio | 92 | 64 | 156 |
| 2023 Junio | 73 | 40 | 113 |
| 2023 Mayo | 104 | 50 | 154 |
| 2023 Abril | 82 | 53 | 135 |
| 2023 Marzo | 88 | 47 | 135 |
| 2023 Febrero | 86 | 42 | 128 |
| 2023 Enero | 88 | 65 | 153 |
| 2022 Diciembre | 72 | 53 | 125 |
| 2022 Noviembre | 41 | 34 | 75 |
| 2022 Octubre | 39 | 31 | 70 |
| 2022 Septiembre | 43 | 57 | 100 |
| 2022 Agosto | 38 | 51 | 89 |
| 2022 Julio | 34 | 46 | 80 |
| 2022 Junio | 34 | 36 | 70 |
| 2022 Mayo | 68 | 61 | 129 |
| 2022 Abril | 84 | 66 | 150 |
| 2022 Marzo | 106 | 75 | 181 |
| 2022 Febrero | 79 | 85 | 164 |
| 2022 Enero | 89 | 46 | 135 |
| 2021 Diciembre | 62 | 55 | 117 |
| 2021 Noviembre | 67 | 54 | 121 |
| 2021 Octubre | 60 | 50 | 110 |
| 2021 Septiembre | 60 | 39 | 99 |
| 2021 Agosto | 42 | 39 | 81 |
| 2021 Julio | 36 | 42 | 78 |
| 2021 Junio | 49 | 40 | 89 |
| 2021 Mayo | 69 | 38 | 107 |
| 2021 Abril | 92 | 61 | 153 |
| 2021 Marzo | 83 | 22 | 105 |
| 2021 Febrero | 50 | 30 | 80 |
| 2021 Enero | 43 | 25 | 68 |
| 2020 Diciembre | 37 | 12 | 49 |
| 2020 Noviembre | 29 | 20 | 49 |
| 2020 Octubre | 36 | 24 | 60 |
| 2020 Septiembre | 39 | 12 | 51 |
| 2020 Agosto | 40 | 21 | 61 |
| 2020 Julio | 23 | 23 | 46 |
| 2020 Junio | 33 | 25 | 58 |
| 2020 Mayo | 21 | 20 | 41 |
| 2020 Abril | 24 | 13 | 37 |
| 2020 Marzo | 22 | 25 | 47 |
| 2020 Febrero | 3 | 8 | 11 |
| 2020 Enero | 4 | 11 | 15 |
| 2019 Diciembre | 8 | 2 | 10 |
| 2019 Noviembre | 4 | 1 | 5 |
| 2019 Octubre | 0 | 1 | 1 |
| 2019 Septiembre | 8 | 3 | 11 |
| 2019 Agosto | 4 | 6 | 10 |
| 2019 Julio | 4 | 13 | 17 |
| 2019 Junio | 4 | 5 | 9 |
| 2019 Mayo | 7 | 11 | 18 |
| 2019 Abril | 2 | 17 | 19 |
| 2019 Marzo | 0 | 12 | 12 |
| 2019 Febrero | 6 | 7 | 13 |
| 2018 Diciembre | 2 | 0 | 2 |
| 2018 Noviembre | 3 | 0 | 3 |
| 2018 Octubre | 3 | 0 | 3 |
| 2018 Septiembre | 4 | 0 | 4 |
| 2018 Marzo | 2 | 0 | 2 |
| 2018 Febrero | 40 | 3 | 43 |
| 2018 Enero | 56 | 7 | 63 |
| 2017 Diciembre | 53 | 6 | 59 |
| 2017 Noviembre | 42 | 5 | 47 |
| 2017 Octubre | 44 | 7 | 51 |
| 2017 Septiembre | 43 | 9 | 52 |
| 2017 Agosto | 40 | 8 | 48 |
| 2017 Julio | 31 | 9 | 40 |
| 2017 Junio | 50 | 10 | 60 |
| 2017 Mayo | 49 | 9 | 58 |
| 2017 Abril | 49 | 7 | 56 |
| 2017 Marzo | 47 | 2 | 49 |
| 2017 Febrero | 23 | 13 | 36 |
| 2017 Enero | 38 | 12 | 50 |
| 2016 Diciembre | 46 | 9 | 55 |
| 2016 Noviembre | 57 | 10 | 67 |
| 2016 Octubre | 66 | 13 | 79 |
| 2016 Septiembre | 96 | 15 | 111 |
| 2016 Agosto | 78 | 16 | 94 |
| 2016 Julio | 57 | 13 | 70 |
| 2016 Junio | 9 | 12 | 21 |
| 2016 Mayo | 5 | 11 | 16 |
| 2016 Abril | 11 | 7 | 18 |
| 2016 Marzo | 9 | 3 | 12 |
| 2016 Febrero | 4 | 2 | 6 |
| 2016 Enero | 7 | 5 | 12 |
| 2015 Diciembre | 6 | 3 | 9 |
| 2015 Noviembre | 6 | 7 | 13 |
| 2015 Octubre | 4 | 3 | 7 |
| 2015 Septiembre | 2 | 3 | 5 |
| 2015 Agosto | 5 | 3 | 8 |
| 2015 Julio | 44 | 7 | 51 |
| 2015 Junio | 48 | 9 | 57 |
| 2015 Mayo | 70 | 12 | 82 |
| 2015 Abril | 48 | 9 | 57 |
| 2015 Marzo | 35 | 13 | 48 |
| 2015 Febrero | 31 | 5 | 36 |
| 2015 Enero | 47 | 7 | 54 |
| 2014 Diciembre | 34 | 5 | 39 |
| 2014 Noviembre | 31 | 5 | 36 |
| 2014 Octubre | 32 | 12 | 44 |
| 2014 Septiembre | 21 | 8 | 29 |
| 2014 Agosto | 24 | 7 | 31 |
| 2014 Julio | 22 | 7 | 29 |
| 2014 Junio | 33 | 10 | 43 |
| 2014 Mayo | 254 | 8 | 262 |
| 2014 Abril | 79 | 5 | 84 |
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