Case and research letter
Dermatosis Neglecta or Terra Firma-Forme Dermatosis
Dermatosis neglecta o terra firma-forme dermatosis
A. Martín-Gorgojo
, V. Alonso-Usero, M. Gavrilova, E. Jordá-Cuevas
Autor para correspondencia
Servicio de Dermatología, Hospital Clínico Universitario de Valencia, Spain
Leído
44519
Vecesse ha leído el artículo
6222
Total PDF
38297
Total HTML
Compartir estadísticas
array:24 [ "pii" => "S1578219012003174" "issn" => "15782190" "doi" => "10.1016/j.adengl.2011.12.006" "estado" => "S300" "fechaPublicacion" => "2012-12-01" "aid" => "638" "copyright" => "Elsevier España, S.L. and AEDV" "copyrightAnyo" => "2011" "documento" => "simple-article" "crossmark" => 0 "subdocumento" => "cor" "cita" => "Actas Dermosifiliogr. 2012;103:932-4" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 20624 "formatos" => array:3 [ "EPUB" => 73 "HTML" => 18052 "PDF" => 2499 ] ] "Traduccion" => array:1 [ "es" => array:19 [ "pii" => "S0001731012002220" "issn" => "00017310" "doi" => "10.1016/j.ad.2011.12.022" "estado" => "S300" "fechaPublicacion" => "2012-12-01" "aid" => "638" "copyright" => "Elsevier España, S.L. y AEDV" "documento" => "simple-article" "crossmark" => 0 "subdocumento" => "cor" "cita" => "Actas Dermosifiliogr. 2012;103:932-4" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 11639 "formatos" => array:3 [ "EPUB" => 6 "HTML" => 8958 "PDF" => 2675 ] ] "es" => array:11 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Carta científico-clínica</span>" "titulo" => "Dermatosis neglecta o <span class="elsevierStyleItalic">terra firma-forme dermatosis</span>" "tienePdf" => "es" "tieneTextoCompleto" => "es" "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "932" "paginaFinal" => "934" ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Dermatosis Neglecta or Terra Firma-Forme Dermatosis" ] ] "contieneTextoCompleto" => array:1 [ "es" => true ] "contienePdf" => array:1 [ "es" => true ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:7 [ "identificador" => "fig0005" "etiqueta" => "Figura 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 1197 "Ancho" => 1583 "Tamanyo" => 141393 ] ] "descripcion" => array:1 [ "es" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Aspecto clínico de las lesiones.</p>" ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "A. Martín-Gorgojo, V. Alonso-Usero, M. Gavrilova, E. Jordá-Cuevas" "autores" => array:4 [ 0 => array:2 [ "nombre" => "A." "apellidos" => "Martín-Gorgojo" ] 1 => array:2 [ "nombre" => "V." "apellidos" => "Alonso-Usero" ] 2 => array:2 [ "nombre" => "M." "apellidos" => "Gavrilova" ] 3 => array:2 [ "nombre" => "E." "apellidos" => "Jordá-Cuevas" ] ] ] ] ] "idiomaDefecto" => "es" "Traduccion" => array:1 [ "en" => array:9 [ "pii" => "S1578219012003174" "doi" => "10.1016/j.adengl.2011.12.006" "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:1 [ "total" => 0 ] "idiomaDefecto" => "en" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219012003174?idApp=UINPBA000044" ] ] "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0001731012002220?idApp=UINPBA000044" "url" => "/00017310/0000010300000010/v1_201304241557/S0001731012002220/v1_201304241557/es/main.assets" ] ] "itemSiguiente" => array:19 [ "pii" => "S1578219012003186" "issn" => "15782190" "doi" => "10.1016/j.adengl.2012.01.023" "estado" => "S300" "fechaPublicacion" => "2012-12-01" "aid" => "623" "copyright" => "Elsevier España, S.L. and AEDV" "documento" => "simple-article" "crossmark" => 0 "subdocumento" => "cor" "cita" => "Actas Dermosifiliogr. 2012;103:934-5" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 4414 "formatos" => array:3 [ "EPUB" => 64 "HTML" => 3204 "PDF" => 1146 ] ] "en" => array:11 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Case and research letter</span>" "titulo" => "Acquired Total Leukonychia in a Patient With Human Immunodeficiency Virus Infection" "tienePdf" => "en" "tieneTextoCompleto" => "en" "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "934" "paginaFinal" => "935" ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Leuconiquia total adquirida en paciente infectado por el virus de la inmunodeficiencia humana" ] ] "contieneTextoCompleto" => array:1 [ "en" => true ] "contienePdf" => array:1 [ "en" => true ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:7 [ "identificador" => "fig0010" "etiqueta" => "Figure 2" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr2.jpeg" "Alto" => 1188 "Ancho" => 1585 "Tamanyo" => 161575 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Detail showing true leukonychia at closer range.</p>" ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "Ú. Pielasinski-Rodríguez, S. Machan, M.C. Fariña-Sabaris, L. Requena-Caballero" "autores" => array:4 [ 0 => array:2 [ "nombre" => "Ú." "apellidos" => "Pielasinski-Rodríguez" ] 1 => array:2 [ "nombre" => "S." "apellidos" => "Machan" ] 2 => array:2 [ "nombre" => "M.C." "apellidos" => "Fariña-Sabaris" ] 3 => array:2 [ "nombre" => "L." "apellidos" => "Requena-Caballero" ] ] ] ] ] "idiomaDefecto" => "en" "Traduccion" => array:1 [ "es" => array:9 [ "pii" => "S0001731012001986" "doi" => "10.1016/j.ad.2012.01.020" "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:1 [ "total" => 0 ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0001731012001986?idApp=UINPBA000044" ] ] "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219012003186?idApp=UINPBA000044" "url" => "/15782190/0000010300000010/v1_201304241352/S1578219012003186/v1_201304241352/en/main.assets" ] "itemAnterior" => array:19 [ "pii" => "S1578219012003162" "issn" => "15782190" "doi" => "10.1016/j.adengl.2011.12.005" "estado" => "S300" "fechaPublicacion" => "2012-12-01" "aid" => "640" "copyright" => "Elsevier España, S.L. and AEDV" "documento" => "simple-article" "crossmark" => 0 "subdocumento" => "cor" "cita" => "Actas Dermosifiliogr. 2012;103:931-2" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 4366 "formatos" => array:3 [ "EPUB" => 47 "HTML" => 3181 "PDF" => 1138 ] ] "en" => array:11 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Case and research letter</span>" "titulo" => "Successful Treatment of Recalcitrant Chronic Foot Eczema with Alitertinoin" "tienePdf" => "en" "tieneTextoCompleto" => "en" "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "931" "paginaFinal" => "932" ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Tratamiento exitoso de un ezcema crónico recalcitrante de las plantas con alitretinoína" ] ] "contieneTextoCompleto" => array:1 [ "en" => true ] "contienePdf" => array:1 [ "en" => true ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:7 [ "identificador" => "fig0005" "etiqueta" => "Figure 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 2385 "Ancho" => 1585 "Tamanyo" => 283953 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">A, Appearance of the eczema on the soles of the feet. B, Lateral view.</p>" ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "A. Tejera-Vaquerizo, J.S. Sánchez-Vizcaíno, V. Haro-Gabaldón" "autores" => array:3 [ 0 => array:2 [ "nombre" => "A." "apellidos" => "Tejera-Vaquerizo" ] 1 => array:2 [ "nombre" => "J.S." "apellidos" => "Sánchez-Vizcaíno" ] 2 => array:2 [ "nombre" => "V." "apellidos" => "Haro-Gabaldón" ] ] ] ] ] "idiomaDefecto" => "en" "Traduccion" => array:1 [ "es" => array:9 [ "pii" => "S0001731012002244" "doi" => "10.1016/j.ad.2011.12.023" "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:1 [ "total" => 0 ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0001731012002244?idApp=UINPBA000044" ] ] "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219012003162?idApp=UINPBA000044" "url" => "/15782190/0000010300000010/v1_201304241352/S1578219012003162/v1_201304241352/en/main.assets" ] "en" => array:14 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Case and research letter</span>" "titulo" => "Dermatosis Neglecta or Terra Firma-Forme Dermatosis" "tieneTextoCompleto" => true "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "932" "paginaFinal" => "934" ] ] "autores" => array:1 [ 0 => array:4 [ "autoresLista" => "A. Martín-Gorgojo, V. Alonso-Usero, M. Gavrilova, E. Jordá-Cuevas" "autores" => array:4 [ 0 => array:4 [ "nombre" => "A." "apellidos" => "Martín-Gorgojo" "email" => array:1 [ 0 => "dr.martingorgojo@gmail.com" ] "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">¿</span>" "identificador" => "cor0005" ] ] ] 1 => array:2 [ "nombre" => "V." "apellidos" => "Alonso-Usero" ] 2 => array:2 [ "nombre" => "M." "apellidos" => "Gavrilova" ] 3 => array:2 [ "nombre" => "E." "apellidos" => "Jordá-Cuevas" ] ] "afiliaciones" => array:1 [ 0 => array:1 [ "entidad" => "Servicio de Dermatología, Hospital Clínico Universitario de Valencia, Spain" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "⁎" "correspondencia" => "Corresponding author." ] ] ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Dermatosis neglecta o <span class="elsevierStyleItalic">terra firma-forme dermatosis</span>" ] ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:7 [ "identificador" => "fig0005" "etiqueta" => "Figure 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 1197 "Ancho" => 1585 "Tamanyo" => 143823 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Clinical appearance of the lesions.</p>" ] ] ] "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">Dermatosis neglecta, or terra firma-forme dermatosis, is a clinical entity whose etiology has still not been fully defined. It is characterized by the presence of asymptomatic, dirtlike hyperpigmented plaques with a slightly papillomatous surface; these plaques cannot be removed with ordinary cleansing but disappear completely on swabbing with 70% ethyl or isopropyl alcohol. We report a new case of this entity.</p><p id="par0010" class="elsevierStylePara elsevierViewall">The patient was a 10-year-old girl with no relevant past medical history. Her mother brought her to our unit for assessment of a persistent asymptomatic skin rash that had appeared several months earlier. Physical examination revealed brownish, reticulated, macular areas that were slightly papillomatous to the touch in some zones. The lesions were distributed symmetrically on the anterior aspect of the trunk, shoulders, and base of the neck (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>). Dermoscopy revealed no melanocytic pattern and no vascular abnormalities, but there were polygonal areas of brownish pigmentation that followed a linear pattern in some places and spared the natural folds of the skin (<a class="elsevierStyleCrossRef" href="#fig0010">Fig. 2</a>).</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><elsevierMultimedia ident="fig0010"></elsevierMultimedia><p id="par0015" class="elsevierStylePara elsevierViewall">Given the distribution and appearance of the lesions, swabbing with a cotton ball soaked in 70% ethyl alcohol was performed as a diagnostic test that doubles as treatment. This procedure cleared the lesions, revealing skin of a normal appearance in the treated area (<a class="elsevierStyleCrossRef" href="#fig0015">Fig. 3</a>). We established a diagnosis of dermatosis neglecta and instructed the patient to apply an exfoliant cream containing keratolytic agents (silica granules, salicylic acid, triclosan, aluminum oxide, and zinc oxide) and then wash the affected areas in order to accelerate the healing and complete resolution of the lesions.</p><elsevierMultimedia ident="fig0015"></elsevierMultimedia><p id="par0020" class="elsevierStylePara elsevierViewall">Terra firma-forme dermatosis is much more common than the literature would lead one to believe. It was first described by Duncan et al.,<a class="elsevierStyleCrossRef" href="#bib0005"><span class="elsevierStyleSup">1</span></a> who reported cases from the 1970s and gave the condition its Latinate name for its earthy or dirtlike appearance. The cause of terra firma-forme dermatosis is not yet fully understood. It is believed that the lesions arise as a consequence of a delay in the maturation of keratinocytes, with melanin retention, and a sustained accumulation of sebum, sweat, corneocytes, and microorganisms in regions in which hygiene measures are less rigorous (e.g. neck, trunk, navel, and flanks), leading to insufficient exfoliation and the formation of a highly adhesive, compact dirt crust.<a class="elsevierStyleCrossRefs" href="#bib0010"><span class="elsevierStyleSup">2,3</span></a> This hypothesis is supported by the fact that these lesions have also been seen in painful areas—in particular hyperesthetic ones—that many patients avoid touching during their hygiene routines (hence the name dermatosis neglecta).<a class="elsevierStyleCrossRef" href="#bib0020"><span class="elsevierStyleSup">4</span></a></p><p id="par0025" class="elsevierStylePara elsevierViewall">Terra firma-forme dermatosis and dermatosis neglecta are widely considered to be synonymous, but some authors have proposed a separation of the terms. Although isolated cases of terra firma-forme dermatosis have been reported in infants, it occurs mainly in older children and adolescents with characteristic hygiene habits and with a distinctive distribution of the lesions,<a class="elsevierStyleCrossRef" href="#bib0025"><span class="elsevierStyleSup">5</span></a> whereas dermatosis neglecta affects patients of any age whose hygiene in specific areas is insufficient.<a class="elsevierStyleCrossRef" href="#bib0030"><span class="elsevierStyleSup">6</span></a></p><p id="par0030" class="elsevierStylePara elsevierViewall">The differential diagnosis of the condition, which has a varied clinical presentation, should include confluent and reticulated papillomatosis of Gougerot and Carteaud (which, in exceptional cases, may partially respond to alcohol swabbing),<a class="elsevierStyleCrossRef" href="#bib0035"><span class="elsevierStyleSup">7</span></a> pityriasis versicolor, acanthosis nigricans, pseudoacanthosis nigricans, psoriasis,<a class="elsevierStyleCrossRef" href="#bib0040"><span class="elsevierStyleSup">8</span></a> dermatitis artefacta, some forms of ichthyosis, and, in certain localized cases, seborrheic keratoses and epidermal nevi.<a class="elsevierStyleCrossRefs" href="#bib0005"><span class="elsevierStyleSup">1,9</span></a></p><p id="par0035" class="elsevierStylePara elsevierViewall">Most cases of dermatosis neglecta can be diagnosed without performing tests other than the alcohol swab test. If performed, histopathologic studies—reported in the literature in just 8 patients to date—generally show epidermal acanthosis and papillomatosis as well as prominent lamellar hyperkeratosis with orthokeratotic whorls. The histopathologic differential diagnosis of dermatosis neglecta must therefore include benign papillomatous entities such as confluent and reticulated papillomatosis, acrokeratosis verruciformis, and epidermal nevi.<a class="elsevierStyleCrossRef" href="#bib0050"><span class="elsevierStyleSup">10</span></a></p><p id="par0040" class="elsevierStylePara elsevierViewall">The condition can be treated with the diagnostic method itself (swabbing with alcohol) or with products such as salicylic-acid-based exfoliants or other keratolytic agents in order to accelerate the normalization of the skin.</p><p id="par0045" class="elsevierStylePara elsevierViewall">We conclude that dermatosis neglecta should be taken into consideration because of its ability to mimic other skin diseases. This entity is much more common than the literature would lead one to believe. In particular, the appearance of hyperpigmented lesions with an unusual pattern should raise suspicion of dermatosis neglecta. In such cases, the alcohol swab test can be very useful.</p></span>" "pdfFichero" => "main.pdf" "tienePdf" => true "NotaPie" => array:1 [ 0 => array:2 [ "etiqueta" => "☆" "nota" => "<p class="elsevierStyleNotepara">Please cite this article as: Martín-Gorgojo A, et al. Dermatosis neglecta or <span class="elsevierStyleItalic">terra firma-forme dermatosis</span>. Actas Dermosifiliogr. 2012;103:932–4.</p>" ] ] "multimedia" => array:3 [ 0 => array:7 [ "identificador" => "fig0005" "etiqueta" => "Figure 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 1197 "Ancho" => 1585 "Tamanyo" => 143823 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Clinical appearance of the lesions.</p>" ] ] 1 => array:7 [ "identificador" => "fig0010" "etiqueta" => "Figure 2" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr2.jpeg" "Alto" => 877 "Ancho" => 1585 "Tamanyo" => 125796 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Dermatoscopy image obtained using a digital contact dermatoscope with immersion fluid.</p>" ] ] 2 => array:7 [ "identificador" => "fig0015" "etiqueta" => "Figure 3" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr3.jpeg" "Alto" => 1182 "Ancho" => 1585 "Tamanyo" => 114830 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">Clinical appearance of the lesions after swabbing with a cotton ball soaked in 70% ethyl alcohol.</p>" ] ] ] "bibliografia" => array:2 [ "titulo" => "References" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:10 [ 0 => array:3 [ "identificador" => "bib0005" "etiqueta" => "1" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Terra firma-forme dermatosis" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "W.C. Duncan" 1 => "J.A. Tschen" 2 => "J.M. Knox" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Arch Dermatol" "fecha" => "1987" "volumen" => "123" "paginaInicial" => "567" "paginaFinal" => "569" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/3579334" "web" => "Medline" ] ] ] ] ] ] ] ] 1 => array:3 [ "identificador" => "bib0010" "etiqueta" => "2" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Terra firma-forme dermatosis" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "C. Guarneri" 1 => "F. Guarneri" 2 => "S.P. Cannavò" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1111/j.1365-4632.2008.03516.x" "Revista" => array:6 [ "tituloSerie" => "Int J Dermatol" "fecha" => "2008" "volumen" => "47" "paginaInicial" => "482" "paginaFinal" => "484" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/18412867" "web" => "Medline" ] ] ] ] ] ] ] ] 2 => array:3 [ "identificador" => "bib0015" "etiqueta" => "3" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Terra Firma forme dermatosis. Case series and review of the literature" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "L. Akkash" 1 => "D. Badran" 2 => "A.Q. Al-Omari" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1111/j.1610-0387.2008.06933.x" "Revista" => array:6 [ "tituloSerie" => "J Dtsch Dermatol Ges" "fecha" => "2009" "volumen" => "7" "paginaInicial" => "102" "paginaFinal" => "107" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/19087214" "web" => "Medline" ] ] ] ] ] ] ] ] 3 => array:3 [ "identificador" => "bib0020" "etiqueta" => "4" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Dermatosis neglecta unmasking recurrence of carcinoma nasopharynx" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "T.P. Vetrichevvel" 1 => "V. Sandhya" 2 => "S. Shobana" 3 => "S. Anandan" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.4103/0378-6323.84084" "Revista" => array:5 [ "tituloSerie" => "Indian J Dermatol Venereol Leprol" "fecha" => "2011" "volumen" => "77" "paginaInicial" => "627" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/21860185" "web" => "Medline" ] ] ] ] ] ] ] ] 4 => array:3 [ "identificador" => "bib0025" "etiqueta" => "5" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Terra firma-forme dermatosis in a 4-month-old girl" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "D.R. Berk" 1 => "A.L. Bruckner" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1111/j.1525-1470.2010.01220.x" "Revista" => array:6 [ "tituloSerie" => "Pediatr Dermatol" "fecha" => "2011" "volumen" => "28" "paginaInicial" => "79" "paginaFinal" => "81" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/20738796" "web" => "Medline" ] ] ] ] ] ] ] ] 5 => array:3 [ "identificador" => "bib0030" "etiqueta" => "6" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Dermatosis neglecta: a series of case reports and review of other dirty-appearing dermatoses" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "J.L. Lucas" 1 => "R.T. Brodell" 2 => "S.R. Feldman" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Dermatol Online J" "fecha" => "2006" "volumen" => "12" "paginaInicial" => "5" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/17459291" "web" => "Medline" ] ] ] ] ] ] ] ] 6 => array:3 [ "identificador" => "bib0035" "etiqueta" => "7" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Confluent and reticulated papillomatosis response to 70% alcohol swabbing" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "D.R. Berk" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1001/archdermatol.2011.1" "Revista" => array:6 [ "tituloSerie" => "Arch Dermatol" "fecha" => "2011" "volumen" => "147" "paginaInicial" => "247" "paginaFinal" => "248" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/21339460" "web" => "Medline" ] ] ] ] ] ] ] ] 7 => array:3 [ "identificador" => "bib0040" "etiqueta" => "8" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "A case of generalized dermatitis neglecta mimicking psoriasis vulgaris" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "J.M. Park" 1 => "M.R. Roh" 2 => "J.E. Kwon" 3 => "K.Y. Lee" 4 => "T.Y. Yoon" 5 => "M.G. Lee" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1001/archdermatol.2010.228" "Revista" => array:6 [ "tituloSerie" => "Arch Dermatol" "fecha" => "2010" "volumen" => "146" "paginaInicial" => "1050" "paginaFinal" => "1051" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/20855717" "web" => "Medline" ] ] ] ] ] ] ] ] 8 => array:3 [ "identificador" => "bib0045" "etiqueta" => "9" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Dermatosis neglecta: dirt crusts simulating verrucous nevi" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "R. Ruiz-Maldonado" 1 => "C. Durán-McKinster" 2 => "L. Tamayo-Sánchez" 3 => "M.L. Orozco-Covarrubias" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Arch Dermatol" "fecha" => "1999" "volumen" => "135" "paginaInicial" => "728" "paginaFinal" => "729" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10376717" "web" => "Medline" ] ] ] ] ] ] ] ] 9 => array:3 [ "identificador" => "bib0050" "etiqueta" => "10" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The histopathology of terra firma-forme dermatosis" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "S.R. Dalton" 1 => "H. Pride" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1111/j.1600-0560.2011.01731_1.x" "Revista" => array:6 [ "tituloSerie" => "J Cutan Pathol" "fecha" => "2011" "volumen" => "38" "paginaInicial" => "537" "paginaFinal" => "539" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/21615764" "web" => "Medline" ] ] ] ] ] ] ] ] ] ] ] ] ] "idiomaDefecto" => "en" "url" => "/15782190/0000010300000010/v1_201304241352/S1578219012003174/v1_201304241352/en/main.assets" "Apartado" => array:4 [ "identificador" => "6157" "tipo" => "SECCION" "en" => array:2 [ "titulo" => "Case and Research Letters" "idiomaDefecto" => true ] "idiomaDefecto" => "en" ] "PDF" => "https://static.elsevier.es/multimedia/15782190/0000010300000010/v1_201304241352/S1578219012003174/v1_201304241352/en/main.pdf?idApp=UINPBA000044&text.app=https://actasdermo.org/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219012003174?idApp=UINPBA000044" ]
| año/Mes | Html | Total | |
|---|---|---|---|
| 2024 Noviembre | 34 | 19 | 53 |
| 2024 Octubre | 385 | 93 | 478 |
| 2024 Septiembre | 449 | 88 | 537 |
| 2024 Agosto | 536 | 120 | 656 |
| 2024 Julio | 519 | 66 | 585 |
| 2024 Junio | 384 | 88 | 472 |
| 2024 Mayo | 526 | 63 | 589 |
| 2024 Abril | 343 | 68 | 411 |
| 2024 Marzo | 393 | 55 | 448 |
| 2024 Febrero | 398 | 70 | 468 |
| 2024 Enero | 325 | 56 | 381 |
| 2023 Diciembre | 353 | 56 | 409 |
| 2023 Noviembre | 522 | 85 | 607 |
| 2023 Octubre | 488 | 66 | 554 |
| 2023 Septiembre | 373 | 45 | 418 |
| 2023 Agosto | 294 | 58 | 352 |
| 2023 Julio | 232 | 89 | 321 |
| 2023 Junio | 314 | 40 | 354 |
| 2023 Mayo | 310 | 81 | 391 |
| 2023 Abril | 231 | 66 | 297 |
| 2023 Marzo | 273 | 37 | 310 |
| 2023 Febrero | 262 | 51 | 313 |
| 2023 Enero | 301 | 72 | 373 |
| 2022 Diciembre | 177 | 78 | 255 |
| 2022 Noviembre | 85 | 51 | 136 |
| 2022 Octubre | 116 | 42 | 158 |
| 2022 Septiembre | 91 | 62 | 153 |
| 2022 Agosto | 86 | 74 | 160 |
| 2022 Julio | 77 | 60 | 137 |
| 2022 Junio | 101 | 51 | 152 |
| 2022 Mayo | 320 | 65 | 385 |
| 2022 Abril | 396 | 75 | 471 |
| 2022 Marzo | 401 | 89 | 490 |
| 2022 Febrero | 414 | 66 | 480 |
| 2022 Enero | 423 | 67 | 490 |
| 2021 Diciembre | 306 | 67 | 373 |
| 2021 Noviembre | 442 | 75 | 517 |
| 2021 Octubre | 1448 | 119 | 1567 |
| 2021 Septiembre | 339 | 88 | 427 |
| 2021 Agosto | 514 | 65 | 579 |
| 2021 Julio | 571 | 62 | 633 |
| 2021 Junio | 737 | 47 | 784 |
| 2021 Mayo | 803 | 65 | 868 |
| 2021 Abril | 869 | 148 | 1017 |
| 2021 Marzo | 743 | 68 | 811 |
| 2021 Febrero | 442 | 56 | 498 |
| 2021 Enero | 282 | 53 | 335 |
| 2020 Diciembre | 267 | 51 | 318 |
| 2020 Noviembre | 214 | 35 | 249 |
| 2020 Octubre | 142 | 52 | 194 |
| 2020 Septiembre | 216 | 53 | 269 |
| 2020 Agosto | 183 | 43 | 226 |
| 2020 Julio | 198 | 48 | 246 |
| 2020 Junio | 174 | 49 | 223 |
| 2020 Mayo | 181 | 55 | 236 |
| 2020 Abril | 144 | 41 | 185 |
| 2020 Marzo | 93 | 61 | 154 |
| 2020 Febrero | 10 | 23 | 33 |
| 2020 Enero | 1 | 16 | 17 |
| 2019 Diciembre | 2 | 22 | 24 |
| 2019 Noviembre | 6 | 12 | 18 |
| 2019 Octubre | 0 | 24 | 24 |
| 2019 Septiembre | 4 | 40 | 44 |
| 2019 Agosto | 6 | 34 | 40 |
| 2019 Julio | 4 | 41 | 45 |
| 2019 Junio | 4 | 45 | 49 |
| 2019 Mayo | 7 | 86 | 93 |
| 2019 Abril | 19 | 71 | 90 |
| 2019 Marzo | 3 | 49 | 52 |
| 2019 Febrero | 2 | 30 | 32 |
| 2019 Enero | 1 | 14 | 15 |
| 2018 Diciembre | 7 | 10 | 17 |
| 2018 Noviembre | 9 | 17 | 26 |
| 2018 Octubre | 6 | 0 | 6 |
| 2018 Septiembre | 11 | 1 | 12 |
| 2018 Agosto | 0 | 25 | 25 |
| 2018 Julio | 0 | 10 | 10 |
| 2018 Junio | 0 | 6 | 6 |
| 2018 Mayo | 1 | 8 | 9 |
| 2018 Abril | 0 | 1 | 1 |
| 2018 Marzo | 149 | 28 | 177 |
| 2018 Febrero | 694 | 30 | 724 |
| 2018 Enero | 728 | 27 | 755 |
| 2017 Diciembre | 610 | 40 | 650 |
| 2017 Noviembre | 720 | 50 | 770 |
| 2017 Octubre | 705 | 32 | 737 |
| 2017 Septiembre | 770 | 28 | 798 |
| 2017 Agosto | 596 | 42 | 638 |
| 2017 Julio | 533 | 21 | 554 |
| 2017 Junio | 740 | 70 | 810 |
| 2017 Mayo | 679 | 51 | 730 |
| 2017 Abril | 698 | 43 | 741 |
| 2017 Marzo | 696 | 42 | 738 |
| 2017 Febrero | 889 | 40 | 929 |
| 2017 Enero | 609 | 26 | 635 |
| 2016 Diciembre | 554 | 20 | 574 |
| 2016 Noviembre | 736 | 28 | 764 |
| 2016 Octubre | 698 | 39 | 737 |
| 2016 Septiembre | 741 | 51 | 792 |
| 2016 Agosto | 761 | 59 | 820 |
| 2016 Julio | 427 | 36 | 463 |
| 2016 Junio | 13 | 36 | 49 |
| 2016 Mayo | 4 | 35 | 39 |
| 2016 Abril | 3 | 2 | 5 |
| 2016 Marzo | 10 | 2 | 12 |
| 2016 Febrero | 7 | 1 | 8 |
| 2016 Enero | 4 | 1 | 5 |
| 2015 Diciembre | 7 | 4 | 11 |
| 2015 Noviembre | 23 | 2 | 25 |
| 2015 Octubre | 30 | 14 | 44 |
| 2015 Septiembre | 27 | 2 | 29 |
| 2015 Agosto | 26 | 8 | 34 |
| 2015 Julio | 421 | 2 | 423 |
| 2015 Junio | 399 | 88 | 487 |
| 2015 Mayo | 397 | 73 | 470 |
| 2015 Abril | 423 | 78 | 501 |
| 2015 Marzo | 562 | 34 | 596 |
| 2015 Febrero | 213 | 29 | 242 |
| 2015 Enero | 231 | 22 | 253 |
| 2014 Diciembre | 160 | 17 | 177 |
| 2014 Noviembre | 191 | 9 | 200 |
| 2014 Octubre | 172 | 8 | 180 |
| 2014 Septiembre | 131 | 13 | 144 |
| 2014 Agosto | 119 | 13 | 132 |
| 2014 Julio | 96 | 18 | 114 |
| 2014 Junio | 76 | 23 | 99 |
| 2014 Mayo | 63 | 22 | 85 |
| 2014 Abril | 27 | 9 | 36 |
| 2014 Marzo | 24 | 48 | 72 |
| 2014 Febrero | 24 | 31 | 55 |
| 2014 Enero | 14 | 29 | 43 |
| 2013 Diciembre | 16 | 30 | 46 |
| 2013 Noviembre | 20 | 29 | 49 |
| 2013 Octubre | 15 | 35 | 50 |
| 2013 Septiembre | 10 | 37 | 47 |
| 2013 Agosto | 11 | 45 | 56 |
| 2013 Julio | 8 | 46 | 54 |
| 2013 Junio | 17 | 78 | 95 |
| 2013 Mayo | 12 | 42 | 54 |
| 2013 Abril | 14 | 48 | 62 |
| 2013 Marzo | 22 | 24 | 46 |
| 2013 Febrero | 45 | 12 | 57 |
| 2013 Enero | 86 | 13 | 99 |
| 2012 Diciembre | 48 | 9 | 57 |
Mostrar todo
