array:24 [
  "pii" => "S1578219012002557"
  "issn" => "15782190"
  "doi" => "10.1016/j.adengl.2012.09.002"
  "estado" => "S300"
  "fechaPublicacion" => "2012-10-01"
  "aid" => "615"
  "copyright" => "Elsevier España, S.L. and AEDV"
  "copyrightAnyo" => "2012"
  "documento" => "simple-article"
  "crossmark" => 0
  "subdocumento" => "cor"
  "cita" => "Actas Dermosifiliogr. 2012;103:735-6"
  "abierto" => array:3 [
    "ES" => true
    "ES2" => true
    "LATM" => true
  ]
  "gratuito" => true
  "lecturas" => array:2 [
    "total" => 2497
    "formatos" => array:3 [
      "EPUB" => 46
      "HTML" => 1908
      "PDF" => 543
    ]
  ]
  "Traduccion" => array:1 [
    "es" => array:19 [
      "pii" => "S0001731012001901"
      "issn" => "00017310"
      "doi" => "10.1016/j.ad.2012.04.003"
      "estado" => "S300"
      "fechaPublicacion" => "2012-10-01"
      "aid" => "615"
      "copyright" => "Elsevier España, S.L. y AEDV"
      "documento" => "simple-article"
      "crossmark" => 0
      "subdocumento" => "cor"
      "cita" => "Actas Dermosifiliogr. 2012;103:735-6"
      "abierto" => array:3 [
        "ES" => true
        "ES2" => true
        "LATM" => true
      ]
      "gratuito" => true
      "lecturas" => array:2 [
        "total" => 3411
        "formatos" => array:3 [
          "EPUB" => 3
          "HTML" => 2615
          "PDF" => 793
        ]
      ]
      "es" => array:11 [
        "idiomaDefecto" => true
        "cabecera" => "<span class="elsevierStyleTextfn">Caso para el diagn&#243;stico</span>"
        "titulo" => "N&#243;dulo malar en un var&#243;n inmunodeprimido"
        "tienePdf" => "es"
        "tieneTextoCompleto" => "es"
        "paginas" => array:1 [
          0 => array:2 [
            "paginaInicial" => "735"
            "paginaFinal" => "736"
          ]
        ]
        "titulosAlternativos" => array:1 [
          "en" => array:1 [
            "titulo" => "Malar Nodule in an Immunosuppressed Man"
          ]
        ]
        "contieneTextoCompleto" => array:1 [
          "es" => true
        ]
        "contienePdf" => array:1 [
          "es" => true
        ]
        "resumenGrafico" => array:2 [
          "original" => 0
          "multimedia" => array:7 [
            "identificador" => "fig0005"
            "etiqueta" => "Figura 1"
            "tipo" => "MULTIMEDIAFIGURA"
            "mostrarFloat" => true
            "mostrarDisplay" => false
            "figura" => array:1 [
              0 => array:4 [
                "imagen" => "gr1.jpeg"
                "Alto" => 2022
                "Ancho" => 1500
                "Tamanyo" => 506010
              ]
            ]
            "descripcion" => array:1 [
              "es" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">N&#243;dulo malar no ulcerado&#46;</p>"
            ]
          ]
        ]
        "autores" => array:1 [
          0 => array:2 [
            "autoresLista" => "A&#46; Pulido P&#233;rez, M&#46;C&#46; Fern&#225;ndez-Ant&#243;n Mart&#237;nez, R&#46; Su&#225;rez Fern&#225;ndez"
            "autores" => array:3 [
              0 => array:2 [
                "nombre" => "A&#46;"
                "apellidos" => "Pulido P&#233;rez"
              ]
              1 => array:2 [
                "nombre" => "M&#46;C&#46;"
                "apellidos" => "Fern&#225;ndez-Ant&#243;n Mart&#237;nez"
              ]
              2 => array:2 [
                "nombre" => "R&#46;"
                "apellidos" => "Su&#225;rez Fern&#225;ndez"
              ]
            ]
          ]
        ]
      ]
      "idiomaDefecto" => "es"
      "Traduccion" => array:1 [
        "en" => array:9 [
          "pii" => "S1578219012002557"
          "doi" => "10.1016/j.adengl.2012.09.002"
          "estado" => "S300"
          "subdocumento" => ""
          "abierto" => array:3 [
            "ES" => true
            "ES2" => true
            "LATM" => true
          ]
          "gratuito" => true
          "lecturas" => array:1 [
            "total" => 0
          ]
          "idiomaDefecto" => "en"
          "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219012002557?idApp=UINPBA000044"
        ]
      ]
      "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0001731012001901?idApp=UINPBA000044"
      "url" => "/00017310/0000010300000008/v1_201304241522/S0001731012001901/v1_201304241522/es/main.assets"
    ]
  ]
  "itemSiguiente" => array:19 [
    "pii" => "S1578219012002661"
    "issn" => "15782190"
    "doi" => "10.1016/j.adengl.2012.09.010"
    "estado" => "S300"
    "fechaPublicacion" => "2012-10-01"
    "aid" => "599"
    "copyright" => "Elsevier Espa&#241;a&#44; S&#46;L&#46; and AEDV"
    "documento" => "article"
    "crossmark" => 0
    "subdocumento" => "sco"
    "cita" => "Actas Dermosifiliogr. 2012;103:737-8"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:2 [
      "total" => 5352
      "formatos" => array:3 [
        "EPUB" => 49
        "HTML" => 2928
        "PDF" => 2375
      ]
    ]
    "en" => array:11 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">VIDEOS OF SURGICAL PROCEDURES IN DERMATOLOGY</span>"
      "titulo" => "Retroauricular Revolving Door Island Flap"
      "tienePdf" => "en"
      "tieneTextoCompleto" => "en"
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "737"
          "paginaFinal" => "738"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "es" => array:1 [
          "titulo" => "Colgajo retroauricular en isla en puerta giratoria"
        ]
      ]
      "contieneTextoCompleto" => array:1 [
        "en" => true
      ]
      "contienePdf" => array:1 [
        "en" => true
      ]
      "resumenGrafico" => array:2 [
        "original" => 0
        "multimedia" => array:6 [
          "identificador" => "fig0020"
          "etiqueta" => "Figure 4"
          "tipo" => "MULTIMEDIAFIGURA"
          "mostrarFloat" => true
          "mostrarDisplay" => false
          "figura" => array:1 [
            0 => array:4 [
              "imagen" => "gr4.jpeg"
              "Alto" => 567
              "Ancho" => 750
              "Tamanyo" => 58365
            ]
          ]
        ]
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "F&#46; Russo de la Torre"
          "autores" => array:1 [
            0 => array:2 [
              "nombre" => "F&#46;"
              "apellidos" => "Russo de la Torre"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "en"
    "Traduccion" => array:1 [
      "es" => array:9 [
        "pii" => "S0001731012001561"
        "doi" => "10.1016/j.ad.2012.04.001"
        "estado" => "S300"
        "subdocumento" => ""
        "abierto" => array:3 [
          "ES" => true
          "ES2" => true
          "LATM" => true
        ]
        "gratuito" => true
        "lecturas" => array:1 [
          "total" => 0
        ]
        "idiomaDefecto" => "es"
        "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0001731012001561?idApp=UINPBA000044"
      ]
    ]
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219012002661?idApp=UINPBA000044"
    "url" => "/15782190/0000010300000008/v1_201304241323/S1578219012002661/v1_201304241323/en/main.assets"
  ]
  "itemAnterior" => array:19 [
    "pii" => "S1578219012002715"
    "issn" => "15782190"
    "doi" => "10.1016/j.adengl.2012.09.015"
    "estado" => "S300"
    "fechaPublicacion" => "2012-10-01"
    "aid" => "595"
    "copyright" => "Elsevier Espa&#241;a&#44; S&#46;L&#46; and AEDV"
    "documento" => "simple-article"
    "crossmark" => 0
    "subdocumento" => "cor"
    "cita" => "Actas Dermosifiliogr. 2012;103:733-4"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:2 [
      "total" => 2717
      "formatos" => array:3 [
        "EPUB" => 46
        "HTML" => 2177
        "PDF" => 494
      ]
    ]
    "en" => array:11 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">Cases for Diagnosis</span>"
      "titulo" => "Chronic Plantar Ulcer in an Immigrant from Africa"
      "tienePdf" => "en"
      "tieneTextoCompleto" => "en"
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "733"
          "paginaFinal" => "734"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "es" => array:1 [
          "titulo" => "&#218;lcera plantar cr&#243;nica en inmigrante africano"
        ]
      ]
      "contieneTextoCompleto" => array:1 [
        "en" => true
      ]
      "contienePdf" => array:1 [
        "en" => true
      ]
      "resumenGrafico" => array:2 [
        "original" => 0
        "multimedia" => array:7 [
          "identificador" => "fig0010"
          "etiqueta" => "Figure 2"
          "tipo" => "MULTIMEDIAFIGURA"
          "mostrarFloat" => true
          "mostrarDisplay" => false
          "figura" => array:1 [
            0 => array:4 [
              "imagen" => "gr2.jpeg"
              "Alto" => 525
              "Ancho" => 402
              "Tamanyo" => 103784
            ]
          ]
          "descripcion" => array:1 [
            "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Hematoxylin-eosin&#44; original magnification &#215;10&#46;</p>"
          ]
        ]
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "A&#46; Molina-Ruiz, E&#46; P&#233;rez-Vega, T&#46; Zulueta-Dorado"
          "autores" => array:3 [
            0 => array:2 [
              "nombre" => "A&#46;"
              "apellidos" => "Molina-Ruiz"
            ]
            1 => array:2 [
              "nombre" => "E&#46;"
              "apellidos" => "P&#233;rez-Vega"
            ]
            2 => array:2 [
              "nombre" => "T&#46;"
              "apellidos" => "Zulueta-Dorado"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "en"
    "Traduccion" => array:1 [
      "es" => array:9 [
        "pii" => "S0001731012001457"
        "doi" => "10.1016/j.ad.2012.02.004"
        "estado" => "S300"
        "subdocumento" => ""
        "abierto" => array:3 [
          "ES" => true
          "ES2" => true
          "LATM" => true
        ]
        "gratuito" => true
        "lecturas" => array:1 [
          "total" => 0
        ]
        "idiomaDefecto" => "es"
        "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0001731012001457?idApp=UINPBA000044"
      ]
    ]
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219012002715?idApp=UINPBA000044"
    "url" => "/15782190/0000010300000008/v1_201304241323/S1578219012002715/v1_201304241323/en/main.assets"
  ]
  "en" => array:15 [
    "idiomaDefecto" => true
    "cabecera" => "<span class="elsevierStyleTextfn">Cases for Diagnosis</span>"
    "titulo" => "Malar Nodule in an Immunosuppressed Man"
    "tieneTextoCompleto" => true
    "paginas" => array:1 [
      0 => array:2 [
        "paginaInicial" => "735"
        "paginaFinal" => "736"
      ]
    ]
    "autores" => array:1 [
      0 => array:4 [
        "autoresLista" => "A&#46; Pulido P&#233;rez, M&#46;C&#46; Fern&#225;ndez-Ant&#243;n Mart&#237;nez, R&#46; Su&#225;rez Fern&#225;ndez"
        "autores" => array:3 [
          0 => array:4 [
            "nombre" => "A&#46;"
            "apellidos" => "Pulido P&#233;rez"
            "email" => array:1 [
              0 => "ana&#46;pulido&#64;madrimasd&#46;net"
            ]
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">¿</span>"
                "identificador" => "cor0005"
              ]
            ]
          ]
          1 => array:2 [
            "nombre" => "M&#46;C&#46;"
            "apellidos" => "Fern&#225;ndez-Ant&#243;n Mart&#237;nez"
          ]
          2 => array:2 [
            "nombre" => "R&#46;"
            "apellidos" => "Su&#225;rez Fern&#225;ndez"
          ]
        ]
        "afiliaciones" => array:1 [
          0 => array:1 [
            "entidad" => "Servicio de Dermatolog&#237;a&#44; Hospital General Universitario Gregorio Mara&#241;&#243;n&#44; Madrid&#44; Spain"
          ]
        ]
        "correspondencia" => array:1 [
          0 => array:3 [
            "identificador" => "cor0005"
            "etiqueta" => "&#8270;"
            "correspondencia" => "Corresponding author&#46;"
          ]
        ]
      ]
    ]
    "titulosAlternativos" => array:1 [
      "es" => array:1 [
        "titulo" => "N&#243;dulo malar en un var&#243;n inmunodeprimido"
      ]
    ]
    "resumenGrafico" => array:2 [
      "original" => 0
      "multimedia" => array:7 [
        "identificador" => "fig0010"
        "etiqueta" => "Figure 2"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr2.jpeg"
            "Alto" => 668
            "Ancho" => 900
            "Tamanyo" => 246606
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Hematoxylin-eosin&#44; original magnification &#215;100&#46;</p>"
        ]
      ]
    ]
    "textoCompleto" => "<span class="elsevierStyleSections"><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle">Medical History</span><p id="par0005" class="elsevierStylePara elsevierViewall">A 72-year-old man was assessed for the sudden onset of an asymptomatic lesion in the malar region associated with a slight worsening of dyspnea but no sputum or fever&#46; The patient had a history of chronic obstructive pulmonary disease for which he had been receiving treatment for several years with inhaled fluticasone propionate and repeated cycles of oral methylprednisolone&#46;</p></span><span id="sec0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle">Physical Examination</span><p id="par0010" class="elsevierStylePara elsevierViewall">Physical examination revealed a nodule of elastic consistency that was nonfluctuant but not attached to the underlying tissue &#40;<a class="elsevierStyleCrossRef" href="#fig0005">Fig&#46; 1</a>&#41;&#46; The surface skin was intact&#44; and no other lesions were present in the mouth or at other sites&#46;</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia></span><span id="sec0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle">Additional Tests</span><p id="par0015" class="elsevierStylePara elsevierViewall">A punch biopsy revealed a whitish-yellow granular material&#44; which was sterile in standard culture media&#46; Histopathology showed an inflammatory infiltrate in the reticular dermis composed of lymphocytes&#44; histiocytes&#44; and numerous polymorphonuclear cells in addition to diffuse structures with basophilic cores surrounded by a filamentous eosinophilic halo &#40;Gram&#44; silver methenamine&#44; and periodic acid-Schiff positive&#41; &#40;<a class="elsevierStyleCrossRef" href="#fig0010">Fig&#46; 2</a>&#41;&#46; Computed tomography of the head&#44; neck&#44; and abdomen revealed multiple minute&#44; cavitated nodules distributed throughout both lung fields&#46; Blood and sputum cultures were sterile&#46;</p><elsevierMultimedia ident="fig0010"></elsevierMultimedia><p id="par0020" class="elsevierStylePara elsevierViewall"><span class="elsevierStyleBold">What Is Your Diagnosis&#63;</span></p></span><span id="sec0020" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle">Diagnosis</span><p id="par0025" class="elsevierStylePara elsevierViewall">Disseminated actinomycosis&#46;</p></span><span id="sec0025" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle">Clinical Course</span><p id="par0030" class="elsevierStylePara elsevierViewall">The clinical&#44; histopathologic&#44; and radiologic findings led to a presumptive diagnosis of disseminated actinomycosis in a patient who had undergone prolonged treatment with steroids&#46; During his hospital stay&#44; the patient received intravenous ceftriaxone and after discharge he continued treatment with oral amoxicillin plus clavulanic acid&#46; Radiologic assessment 3 months after completion of antibiotic treatment showed a considerable reduction in lung involvement&#44; with no evidence of recurrence or new subcutaneous nodular lesions&#46;</p></span><span id="sec0030" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle">Discussion</span><p id="par0035" class="elsevierStylePara elsevierViewall">Actinomycosis is a chronic suppurative disease caused by gram-positive&#44; non-acid-fast bacteria of the <span class="elsevierStyleItalic">Actinomyces</span> genus&#46;<a class="elsevierStyleCrossRef" href="#bib0005"><span class="elsevierStyleSup">1</span></a> These colonizing microorganisms are normally found in the gastrointestinal tract &#40;from the oropharynx to the distal intestine&#41; and the female genital apparatus&#44; but they are considered to be opportunistic pathogens in specific situations&#44; such as immunosuppression&#44; diabetes mellitus&#44; impaired mucosal barrier&#44; and bronchial aspiration&#46; The most common clinical forms are cervicofacial&#44; lung&#44; and abdominal&#46;<a class="elsevierStyleCrossRef" href="#bib0010"><span class="elsevierStyleSup">2</span></a> Skin involvement can be the result of contiguous spread resulting from maxillofacial injury or dental work&#44; or may be caused by dissemination through the blood stream from a primary infection in one of the sites mentioned above&#46; Clinically the lesions are asymptomatic&#44; slow-growing abscesses or nodules with a tendency to fistulize&#46; They exude a yellowish-white granular material &#40;also known as sulfur granules&#41;&#44; which contains filamentous bacterial colonies&#44; associated with tissue elements in the exudate&#46;<a class="elsevierStyleCrossRef" href="#bib0015"><span class="elsevierStyleSup">3</span></a></p><p id="par0040" class="elsevierStylePara elsevierViewall">Microbiological diagnosis is usually difficult for a variety of reasons&#44; including the presence of other microorganisms in the samples and prior antibiotic treatment However&#44; one of the main causes of the failure to diagnose this condition&#44; particularly in extra-mandibular sites&#44; is the failure to obtain and transport the sample under anaerobic conditions as a result of a low level of clinical suspicion&#46;<a class="elsevierStyleCrossRefs" href="#bib0020"><span class="elsevierStyleSup">4&#8211;6</span></a> Blood and sputum cultures are usually negative in the pulmonary and disseminated forms&#46; When microbiological isolation fails&#44; treatment with beta-lactam antibiotics should be administered to patients who present symptoms suggestive of infection with bacteria of the genus <span class="elsevierStyleItalic">Actinomyces</span> in the presence of histopathologic findings compatible with this diagnosis&#46;<a class="elsevierStyleCrossRef" href="#bib0035"><span class="elsevierStyleSup">7</span></a> The differential diagnosis should include adnexal tumors&#44; infundibular cysts&#44; skin metastases&#44; and other disorders caused by agents that produce actinomycetoma&#44; such as <span class="elsevierStyleItalic">Nocardia</span> and <span class="elsevierStyleItalic">Streptomyces somaliensis</span> species&#46;</p><p id="par0045" class="elsevierStylePara elsevierViewall">While various antibiotics are effective against <span class="elsevierStyleItalic">Actinomyces</span>&#44; beta-lactam antibiotics &#40;penicillin&#44; ampicillin&#44; amoxicillin&#44; cephalosporins&#41; are the first-line option&#46; Clindamycin&#44; doxycycline&#44; and macrolides can be used for patients allergic to beta-lactams&#46; Surgical drainage should be performed if the lesions are accessible&#46;</p></span><span id="sec0035" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle">Conflicts of Interest</span><p id="par0050" class="elsevierStylePara elsevierViewall">The authors declare that they have no conflicts of interest&#46;</p></span></span>"
    "textoCompletoSecciones" => array:1 [
      "secciones" => array:8 [
        0 => array:2 [
          "identificador" => "sec0005"
          "titulo" => "Medical History"
        ]
        1 => array:2 [
          "identificador" => "sec0010"
          "titulo" => "Physical Examination"
        ]
        2 => array:2 [
          "identificador" => "sec0015"
          "titulo" => "Additional Tests"
        ]
        3 => array:2 [
          "identificador" => "sec0020"
          "titulo" => "Diagnosis"
        ]
        4 => array:2 [
          "identificador" => "sec0025"
          "titulo" => "Clinical Course"
        ]
        5 => array:2 [
          "identificador" => "sec0030"
          "titulo" => "Discussion"
        ]
        6 => array:2 [
          "identificador" => "sec0035"
          "titulo" => "Conflicts of Interest"
        ]
        7 => array:1 [
          "titulo" => "References"
        ]
      ]
    ]
    "pdfFichero" => "main.pdf"
    "tienePdf" => true
    "NotaPie" => array:1 [
      0 => array:2 [
        "etiqueta" => "&#9734;"
        "nota" => "<p class="elsevierStyleNotepara">Please cite this article as&#58; Pulido P&#233;rez A&#44; Fern&#225;ndez-Ant&#243;n Mart&#237;nez MC&#44; Su&#225;rez Fern&#225;ndez R&#46; N&#243;dulo malar en un var&#243;n inmunodeprimido&#46; Actas Dermosifiliogr&#46;2012&#59;103&#58;735-736&#46;</p>"
      ]
    ]
    "multimedia" => array:2 [
      0 => array:7 [
        "identificador" => "fig0005"
        "etiqueta" => "Figure 1"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr1.jpeg"
            "Alto" => 1213
            "Ancho" => 900
            "Tamanyo" => 210961
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Nonulcerated malar nodule&#46;</p>"
        ]
      ]
      1 => array:7 [
        "identificador" => "fig0010"
        "etiqueta" => "Figure 2"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr2.jpeg"
            "Alto" => 668
            "Ancho" => 900
            "Tamanyo" => 246606
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Hematoxylin-eosin&#44; original magnification &#215;100&#46;</p>"
        ]
      ]
    ]
    "bibliografia" => array:2 [
      "titulo" => "References"
      "seccion" => array:1 [
        0 => array:2 [
          "identificador" => "bibs0005"
          "bibliografiaReferencia" => array:7 [
            0 => array:3 [
              "identificador" => "bib0005"
              "etiqueta" => "1"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Actinomycosis"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "V&#46;K&#46; Wong"
                            1 => "T&#46;D&#46; Turmezei"
                            2 => "V&#46;C&#46; Weston"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "BMJ"
                        "fecha" => "2011"
                        "volumen" => "343"
                        "paginaInicial" => "d6099"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/21990282"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            1 => array:3 [
              "identificador" => "bib0010"
              "etiqueta" => "2"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Actinomicosis orocervicofacial&#46; Presentaci&#243;n de 5 casos"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "K&#46; Aguirrebengoa"
                            1 => "M&#46; Roma&#241;a"
                            2 => "L&#46; L&#243;pez"
                            3 => "J&#46; Mart&#237;n"
                            4 => "M&#46; Montejo"
                            5 => "P&#46; Gonz&#225;lez de Z&#225;rate"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Enferm Infecc Microbiol Clin"
                        "fecha" => "2002"
                        "volumen" => "20"
                        "paginaInicial" => "53"
                        "paginaFinal" => "56"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11886672"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            2 => array:3 [
              "identificador" => "bib0015"
              "etiqueta" => "3"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Primary cutaneous actinomycosis"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "D&#46; Patil"
                            1 => "B&#46; Siddaramappa"
                            2 => "B&#46;S&#46; Manjunathswamy"
                            3 => "A&#46;M&#46; Pandit"
                            4 => "S&#46; Dastikop"
                            5 => "C&#46; Fernandes"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1111/j.1365-4632.2008.03854.x"
                      "Revista" => array:6 [
                        "tituloSerie" => "Int J Dermatol"
                        "fecha" => "2008"
                        "volumen" => "47"
                        "paginaInicial" => "1271"
                        "paginaFinal" => "1273"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/19126014"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            3 => array:3 [
              "identificador" => "bib0020"
              "etiqueta" => "4"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Cutaneous actinomycosis&#58; the great mimicker"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "H&#46;A&#46; Ngow"
                            1 => "W&#46;N&#46; Wan Khairina"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1136/jcp.2008.063842"
                      "Revista" => array:5 [
                        "tituloSerie" => "J Clin Pathol"
                        "fecha" => "2009"
                        "volumen" => "62"
                        "paginaInicial" => "766"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/19638556"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            4 => array:3 [
              "identificador" => "bib0025"
              "etiqueta" => "5"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Cervicofacial actinomycosis resembling a ruptured cyst"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "V&#46; Cirillo-Hyland"
                            1 => "A&#46; Herzberg"
                            2 => "C&#46; Jaworsky"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "J Am Acad Dermatol"
                        "fecha" => "1993"
                        "volumen" => "29"
                        "paginaInicial" => "308"
                        "paginaFinal" => "311"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8340504"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            5 => array:3 [
              "identificador" => "bib0030"
              "etiqueta" => "6"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Abscesses from actinomyces infection&#58; why so difficult to diagnose&#63;"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "I&#46; Brook"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1586/eri.11.142"
                      "Revista" => array:6 [
                        "tituloSerie" => "Expert Rev Anti Infect Ther"
                        "fecha" => "2011"
                        "volumen" => "9"
                        "paginaInicial" => "1097"
                        "paginaFinal" => "1099"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/22114958"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            6 => array:3 [
              "identificador" => "bib0035"
              "etiqueta" => "7"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Actinomycosis&#58; diagnosis and management"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "I&#46; Brook"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1097/SMJ.0b013e3181864c1f"
                      "Revista" => array:6 [
                        "tituloSerie" => "South Med J"
                        "fecha" => "2008"
                        "volumen" => "101"
                        "paginaInicial" => "1019"
                        "paginaFinal" => "1023"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/18791528"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
          ]
        ]
      ]
    ]
  ]
  "idiomaDefecto" => "en"
  "url" => "/15782190/0000010300000008/v1_201304241323/S1578219012002557/v1_201304241323/en/main.assets"
  "Apartado" => array:4 [
    "identificador" => "6154"
    "tipo" => "SECCION"
    "en" => array:2 [
      "titulo" => "Case for Diagnosis"
      "idiomaDefecto" => true
    ]
    "idiomaDefecto" => "en"
  ]
  "PDF" => "https://static.elsevier.es/multimedia/15782190/0000010300000008/v1_201304241323/S1578219012002557/v1_201304241323/en/main.pdf?idApp=UINPBA000044&text.app=https://actasdermo.org/"
  "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219012002557?idApp=UINPBA000044"
]
Compartir
Información de la revista

Estadísticas

Siga este enlace para acceder al texto completo del artículo

Cases for Diagnosis
Malar Nodule in an Immunosuppressed Man
Nódulo malar en un varón inmunodeprimido
A. Pulido Pérez
Autor para correspondencia
ana.pulido@madrimasd.net

Corresponding author.
, M.C. Fernández-Antón Martínez, R. Suárez Fernández
Servicio de Dermatología, Hospital General Universitario Gregorio Marañón, Madrid, Spain
Leído
6692
Veces
se ha leído el artículo
2225
Total PDF
4467
Total HTML
Compartir estadísticas
 array:24 [
  "pii" => "S1578219012002557"
  "issn" => "15782190"
  "doi" => "10.1016/j.adengl.2012.09.002"
  "estado" => "S300"
  "fechaPublicacion" => "2012-10-01"
  "aid" => "615"
  "copyright" => "Elsevier Espa&#241;a&#44; S&#46;L&#46; and AEDV"
  "copyrightAnyo" => "2012"
  "documento" => "simple-article"
  "crossmark" => 0
  "subdocumento" => "cor"
  "cita" => "Actas Dermosifiliogr. 2012;103:735-6"
  "abierto" => array:3 [
    "ES" => true
    "ES2" => true
    "LATM" => true
  ]
  "gratuito" => true
  "lecturas" => array:2 [
    "total" => 2497
    "formatos" => array:3 [
      "EPUB" => 46
      "HTML" => 1908
      "PDF" => 543
    ]
  ]
  "Traduccion" => array:1 [
    "es" => array:19 [
      "pii" => "S0001731012001901"
      "issn" => "00017310"
      "doi" => "10.1016/j.ad.2012.04.003"
      "estado" => "S300"
      "fechaPublicacion" => "2012-10-01"
      "aid" => "615"
      "copyright" => "Elsevier Espa&#241;a&#44; S&#46;L&#46; y AEDV"
      "documento" => "simple-article"
      "crossmark" => 0
      "subdocumento" => "cor"
      "cita" => "Actas Dermosifiliogr. 2012;103:735-6"
      "abierto" => array:3 [
        "ES" => true
        "ES2" => true
        "LATM" => true
      ]
      "gratuito" => true
      "lecturas" => array:2 [
        "total" => 3411
        "formatos" => array:3 [
          "EPUB" => 3
          "HTML" => 2615
          "PDF" => 793
        ]
      ]
      "es" => array:11 [
        "idiomaDefecto" => true
        "cabecera" => "<span class="elsevierStyleTextfn">Caso para el diagn&#243;stico</span>"
        "titulo" => "N&#243;dulo malar en un var&#243;n inmunodeprimido"
        "tienePdf" => "es"
        "tieneTextoCompleto" => "es"
        "paginas" => array:1 [
          0 => array:2 [
            "paginaInicial" => "735"
            "paginaFinal" => "736"
          ]
        ]
        "titulosAlternativos" => array:1 [
          "en" => array:1 [
            "titulo" => "Malar Nodule in an Immunosuppressed Man"
          ]
        ]
        "contieneTextoCompleto" => array:1 [
          "es" => true
        ]
        "contienePdf" => array:1 [
          "es" => true
        ]
        "resumenGrafico" => array:2 [
          "original" => 0
          "multimedia" => array:7 [
            "identificador" => "fig0005"
            "etiqueta" => "Figura 1"
            "tipo" => "MULTIMEDIAFIGURA"
            "mostrarFloat" => true
            "mostrarDisplay" => false
            "figura" => array:1 [
              0 => array:4 [
                "imagen" => "gr1.jpeg"
                "Alto" => 2022
                "Ancho" => 1500
                "Tamanyo" => 506010
              ]
            ]
            "descripcion" => array:1 [
              "es" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">N&#243;dulo malar no ulcerado&#46;</p>"
            ]
          ]
        ]
        "autores" => array:1 [
          0 => array:2 [
            "autoresLista" => "A&#46; Pulido P&#233;rez, M&#46;C&#46; Fern&#225;ndez-Ant&#243;n Mart&#237;nez, R&#46; Su&#225;rez Fern&#225;ndez"
            "autores" => array:3 [
              0 => array:2 [
                "nombre" => "A&#46;"
                "apellidos" => "Pulido P&#233;rez"
              ]
              1 => array:2 [
                "nombre" => "M&#46;C&#46;"
                "apellidos" => "Fern&#225;ndez-Ant&#243;n Mart&#237;nez"
              ]
              2 => array:2 [
                "nombre" => "R&#46;"
                "apellidos" => "Su&#225;rez Fern&#225;ndez"
              ]
            ]
          ]
        ]
      ]
      "idiomaDefecto" => "es"
      "Traduccion" => array:1 [
        "en" => array:9 [
          "pii" => "S1578219012002557"
          "doi" => "10.1016/j.adengl.2012.09.002"
          "estado" => "S300"
          "subdocumento" => ""
          "abierto" => array:3 [
            "ES" => true
            "ES2" => true
            "LATM" => true
          ]
          "gratuito" => true
          "lecturas" => array:1 [
            "total" => 0
          ]
          "idiomaDefecto" => "en"
          "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219012002557?idApp=UINPBA000044"
        ]
      ]
      "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0001731012001901?idApp=UINPBA000044"
      "url" => "/00017310/0000010300000008/v1_201304241522/S0001731012001901/v1_201304241522/es/main.assets"
    ]
  ]
  "itemSiguiente" => array:19 [
    "pii" => "S1578219012002661"
    "issn" => "15782190"
    "doi" => "10.1016/j.adengl.2012.09.010"
    "estado" => "S300"
    "fechaPublicacion" => "2012-10-01"
    "aid" => "599"
    "copyright" => "Elsevier Espa&#241;a&#44; S&#46;L&#46; and AEDV"
    "documento" => "article"
    "crossmark" => 0
    "subdocumento" => "sco"
    "cita" => "Actas Dermosifiliogr. 2012;103:737-8"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:2 [
      "total" => 5352
      "formatos" => array:3 [
        "EPUB" => 49
        "HTML" => 2928
        "PDF" => 2375
      ]
    ]
    "en" => array:11 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">VIDEOS OF SURGICAL PROCEDURES IN DERMATOLOGY</span>"
      "titulo" => "Retroauricular Revolving Door Island Flap"
      "tienePdf" => "en"
      "tieneTextoCompleto" => "en"
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "737"
          "paginaFinal" => "738"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "es" => array:1 [
          "titulo" => "Colgajo retroauricular en isla en puerta giratoria"
        ]
      ]
      "contieneTextoCompleto" => array:1 [
        "en" => true
      ]
      "contienePdf" => array:1 [
        "en" => true
      ]
      "resumenGrafico" => array:2 [
        "original" => 0
        "multimedia" => array:6 [
          "identificador" => "fig0020"
          "etiqueta" => "Figure 4"
          "tipo" => "MULTIMEDIAFIGURA"
          "mostrarFloat" => true
          "mostrarDisplay" => false
          "figura" => array:1 [
            0 => array:4 [
              "imagen" => "gr4.jpeg"
              "Alto" => 567
              "Ancho" => 750
              "Tamanyo" => 58365
            ]
          ]
        ]
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "F&#46; Russo de la Torre"
          "autores" => array:1 [
            0 => array:2 [
              "nombre" => "F&#46;"
              "apellidos" => "Russo de la Torre"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "en"
    "Traduccion" => array:1 [
      "es" => array:9 [
        "pii" => "S0001731012001561"
        "doi" => "10.1016/j.ad.2012.04.001"
        "estado" => "S300"
        "subdocumento" => ""
        "abierto" => array:3 [
          "ES" => true
          "ES2" => true
          "LATM" => true
        ]
        "gratuito" => true
        "lecturas" => array:1 [
          "total" => 0
        ]
        "idiomaDefecto" => "es"
        "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0001731012001561?idApp=UINPBA000044"
      ]
    ]
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219012002661?idApp=UINPBA000044"
    "url" => "/15782190/0000010300000008/v1_201304241323/S1578219012002661/v1_201304241323/en/main.assets"
  ]
  "itemAnterior" => array:19 [
    "pii" => "S1578219012002715"
    "issn" => "15782190"
    "doi" => "10.1016/j.adengl.2012.09.015"
    "estado" => "S300"
    "fechaPublicacion" => "2012-10-01"
    "aid" => "595"
    "copyright" => "Elsevier Espa&#241;a&#44; S&#46;L&#46; and AEDV"
    "documento" => "simple-article"
    "crossmark" => 0
    "subdocumento" => "cor"
    "cita" => "Actas Dermosifiliogr. 2012;103:733-4"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:2 [
      "total" => 2717
      "formatos" => array:3 [
        "EPUB" => 46
        "HTML" => 2177
        "PDF" => 494
      ]
    ]
    "en" => array:11 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">Cases for Diagnosis</span>"
      "titulo" => "Chronic Plantar Ulcer in an Immigrant from Africa"
      "tienePdf" => "en"
      "tieneTextoCompleto" => "en"
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "733"
          "paginaFinal" => "734"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "es" => array:1 [
          "titulo" => "&#218;lcera plantar cr&#243;nica en inmigrante africano"
        ]
      ]
      "contieneTextoCompleto" => array:1 [
        "en" => true
      ]
      "contienePdf" => array:1 [
        "en" => true
      ]
      "resumenGrafico" => array:2 [
        "original" => 0
        "multimedia" => array:7 [
          "identificador" => "fig0010"
          "etiqueta" => "Figure 2"
          "tipo" => "MULTIMEDIAFIGURA"
          "mostrarFloat" => true
          "mostrarDisplay" => false
          "figura" => array:1 [
            0 => array:4 [
              "imagen" => "gr2.jpeg"
              "Alto" => 525
              "Ancho" => 402
              "Tamanyo" => 103784
            ]
          ]
          "descripcion" => array:1 [
            "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Hematoxylin-eosin&#44; original magnification &#215;10&#46;</p>"
          ]
        ]
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "A&#46; Molina-Ruiz, E&#46; P&#233;rez-Vega, T&#46; Zulueta-Dorado"
          "autores" => array:3 [
            0 => array:2 [
              "nombre" => "A&#46;"
              "apellidos" => "Molina-Ruiz"
            ]
            1 => array:2 [
              "nombre" => "E&#46;"
              "apellidos" => "P&#233;rez-Vega"
            ]
            2 => array:2 [
              "nombre" => "T&#46;"
              "apellidos" => "Zulueta-Dorado"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "en"
    "Traduccion" => array:1 [
      "es" => array:9 [
        "pii" => "S0001731012001457"
        "doi" => "10.1016/j.ad.2012.02.004"
        "estado" => "S300"
        "subdocumento" => ""
        "abierto" => array:3 [
          "ES" => true
          "ES2" => true
          "LATM" => true
        ]
        "gratuito" => true
        "lecturas" => array:1 [
          "total" => 0
        ]
        "idiomaDefecto" => "es"
        "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0001731012001457?idApp=UINPBA000044"
      ]
    ]
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219012002715?idApp=UINPBA000044"
    "url" => "/15782190/0000010300000008/v1_201304241323/S1578219012002715/v1_201304241323/en/main.assets"
  ]
  "en" => array:15 [
    "idiomaDefecto" => true
    "cabecera" => "<span class="elsevierStyleTextfn">Cases for Diagnosis</span>"
    "titulo" => "Malar Nodule in an Immunosuppressed Man"
    "tieneTextoCompleto" => true
    "paginas" => array:1 [
      0 => array:2 [
        "paginaInicial" => "735"
        "paginaFinal" => "736"
      ]
    ]
    "autores" => array:1 [
      0 => array:4 [
        "autoresLista" => "A&#46; Pulido P&#233;rez, M&#46;C&#46; Fern&#225;ndez-Ant&#243;n Mart&#237;nez, R&#46; Su&#225;rez Fern&#225;ndez"
        "autores" => array:3 [
          0 => array:4 [
            "nombre" => "A&#46;"
            "apellidos" => "Pulido P&#233;rez"
            "email" => array:1 [
              0 => "ana&#46;pulido&#64;madrimasd&#46;net"
            ]
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">¿</span>"
                "identificador" => "cor0005"
              ]
            ]
          ]
          1 => array:2 [
            "nombre" => "M&#46;C&#46;"
            "apellidos" => "Fern&#225;ndez-Ant&#243;n Mart&#237;nez"
          ]
          2 => array:2 [
            "nombre" => "R&#46;"
            "apellidos" => "Su&#225;rez Fern&#225;ndez"
          ]
        ]
        "afiliaciones" => array:1 [
          0 => array:1 [
            "entidad" => "Servicio de Dermatolog&#237;a&#44; Hospital General Universitario Gregorio Mara&#241;&#243;n&#44; Madrid&#44; Spain"
          ]
        ]
        "correspondencia" => array:1 [
          0 => array:3 [
            "identificador" => "cor0005"
            "etiqueta" => "&#8270;"
            "correspondencia" => "Corresponding author&#46;"
          ]
        ]
      ]
    ]
    "titulosAlternativos" => array:1 [
      "es" => array:1 [
        "titulo" => "N&#243;dulo malar en un var&#243;n inmunodeprimido"
      ]
    ]
    "resumenGrafico" => array:2 [
      "original" => 0
      "multimedia" => array:7 [
        "identificador" => "fig0010"
        "etiqueta" => "Figure 2"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr2.jpeg"
            "Alto" => 668
            "Ancho" => 900
            "Tamanyo" => 246606
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Hematoxylin-eosin&#44; original magnification &#215;100&#46;</p>"
        ]
      ]
    ]
    "textoCompleto" => "<span class="elsevierStyleSections"><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle">Medical History</span><p id="par0005" class="elsevierStylePara elsevierViewall">A 72-year-old man was assessed for the sudden onset of an asymptomatic lesion in the malar region associated with a slight worsening of dyspnea but no sputum or fever&#46; The patient had a history of chronic obstructive pulmonary disease for which he had been receiving treatment for several years with inhaled fluticasone propionate and repeated cycles of oral methylprednisolone&#46;</p></span><span id="sec0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle">Physical Examination</span><p id="par0010" class="elsevierStylePara elsevierViewall">Physical examination revealed a nodule of elastic consistency that was nonfluctuant but not attached to the underlying tissue &#40;<a class="elsevierStyleCrossRef" href="#fig0005">Fig&#46; 1</a>&#41;&#46; The surface skin was intact&#44; and no other lesions were present in the mouth or at other sites&#46;</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia></span><span id="sec0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle">Additional Tests</span><p id="par0015" class="elsevierStylePara elsevierViewall">A punch biopsy revealed a whitish-yellow granular material&#44; which was sterile in standard culture media&#46; Histopathology showed an inflammatory infiltrate in the reticular dermis composed of lymphocytes&#44; histiocytes&#44; and numerous polymorphonuclear cells in addition to diffuse structures with basophilic cores surrounded by a filamentous eosinophilic halo &#40;Gram&#44; silver methenamine&#44; and periodic acid-Schiff positive&#41; &#40;<a class="elsevierStyleCrossRef" href="#fig0010">Fig&#46; 2</a>&#41;&#46; Computed tomography of the head&#44; neck&#44; and abdomen revealed multiple minute&#44; cavitated nodules distributed throughout both lung fields&#46; Blood and sputum cultures were sterile&#46;</p><elsevierMultimedia ident="fig0010"></elsevierMultimedia><p id="par0020" class="elsevierStylePara elsevierViewall"><span class="elsevierStyleBold">What Is Your Diagnosis&#63;</span></p></span><span id="sec0020" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle">Diagnosis</span><p id="par0025" class="elsevierStylePara elsevierViewall">Disseminated actinomycosis&#46;</p></span><span id="sec0025" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle">Clinical Course</span><p id="par0030" class="elsevierStylePara elsevierViewall">The clinical&#44; histopathologic&#44; and radiologic findings led to a presumptive diagnosis of disseminated actinomycosis in a patient who had undergone prolonged treatment with steroids&#46; During his hospital stay&#44; the patient received intravenous ceftriaxone and after discharge he continued treatment with oral amoxicillin plus clavulanic acid&#46; Radiologic assessment 3 months after completion of antibiotic treatment showed a considerable reduction in lung involvement&#44; with no evidence of recurrence or new subcutaneous nodular lesions&#46;</p></span><span id="sec0030" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle">Discussion</span><p id="par0035" class="elsevierStylePara elsevierViewall">Actinomycosis is a chronic suppurative disease caused by gram-positive&#44; non-acid-fast bacteria of the <span class="elsevierStyleItalic">Actinomyces</span> genus&#46;<a class="elsevierStyleCrossRef" href="#bib0005"><span class="elsevierStyleSup">1</span></a> These colonizing microorganisms are normally found in the gastrointestinal tract &#40;from the oropharynx to the distal intestine&#41; and the female genital apparatus&#44; but they are considered to be opportunistic pathogens in specific situations&#44; such as immunosuppression&#44; diabetes mellitus&#44; impaired mucosal barrier&#44; and bronchial aspiration&#46; The most common clinical forms are cervicofacial&#44; lung&#44; and abdominal&#46;<a class="elsevierStyleCrossRef" href="#bib0010"><span class="elsevierStyleSup">2</span></a> Skin involvement can be the result of contiguous spread resulting from maxillofacial injury or dental work&#44; or may be caused by dissemination through the blood stream from a primary infection in one of the sites mentioned above&#46; Clinically the lesions are asymptomatic&#44; slow-growing abscesses or nodules with a tendency to fistulize&#46; They exude a yellowish-white granular material &#40;also known as sulfur granules&#41;&#44; which contains filamentous bacterial colonies&#44; associated with tissue elements in the exudate&#46;<a class="elsevierStyleCrossRef" href="#bib0015"><span class="elsevierStyleSup">3</span></a></p><p id="par0040" class="elsevierStylePara elsevierViewall">Microbiological diagnosis is usually difficult for a variety of reasons&#44; including the presence of other microorganisms in the samples and prior antibiotic treatment However&#44; one of the main causes of the failure to diagnose this condition&#44; particularly in extra-mandibular sites&#44; is the failure to obtain and transport the sample under anaerobic conditions as a result of a low level of clinical suspicion&#46;<a class="elsevierStyleCrossRefs" href="#bib0020"><span class="elsevierStyleSup">4&#8211;6</span></a> Blood and sputum cultures are usually negative in the pulmonary and disseminated forms&#46; When microbiological isolation fails&#44; treatment with beta-lactam antibiotics should be administered to patients who present symptoms suggestive of infection with bacteria of the genus <span class="elsevierStyleItalic">Actinomyces</span> in the presence of histopathologic findings compatible with this diagnosis&#46;<a class="elsevierStyleCrossRef" href="#bib0035"><span class="elsevierStyleSup">7</span></a> The differential diagnosis should include adnexal tumors&#44; infundibular cysts&#44; skin metastases&#44; and other disorders caused by agents that produce actinomycetoma&#44; such as <span class="elsevierStyleItalic">Nocardia</span> and <span class="elsevierStyleItalic">Streptomyces somaliensis</span> species&#46;</p><p id="par0045" class="elsevierStylePara elsevierViewall">While various antibiotics are effective against <span class="elsevierStyleItalic">Actinomyces</span>&#44; beta-lactam antibiotics &#40;penicillin&#44; ampicillin&#44; amoxicillin&#44; cephalosporins&#41; are the first-line option&#46; Clindamycin&#44; doxycycline&#44; and macrolides can be used for patients allergic to beta-lactams&#46; Surgical drainage should be performed if the lesions are accessible&#46;</p></span><span id="sec0035" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle">Conflicts of Interest</span><p id="par0050" class="elsevierStylePara elsevierViewall">The authors declare that they have no conflicts of interest&#46;</p></span></span>"
    "textoCompletoSecciones" => array:1 [
      "secciones" => array:8 [
        0 => array:2 [
          "identificador" => "sec0005"
          "titulo" => "Medical History"
        ]
        1 => array:2 [
          "identificador" => "sec0010"
          "titulo" => "Physical Examination"
        ]
        2 => array:2 [
          "identificador" => "sec0015"
          "titulo" => "Additional Tests"
        ]
        3 => array:2 [
          "identificador" => "sec0020"
          "titulo" => "Diagnosis"
        ]
        4 => array:2 [
          "identificador" => "sec0025"
          "titulo" => "Clinical Course"
        ]
        5 => array:2 [
          "identificador" => "sec0030"
          "titulo" => "Discussion"
        ]
        6 => array:2 [
          "identificador" => "sec0035"
          "titulo" => "Conflicts of Interest"
        ]
        7 => array:1 [
          "titulo" => "References"
        ]
      ]
    ]
    "pdfFichero" => "main.pdf"
    "tienePdf" => true
    "NotaPie" => array:1 [
      0 => array:2 [
        "etiqueta" => "&#9734;"
        "nota" => "<p class="elsevierStyleNotepara">Please cite this article as&#58; Pulido P&#233;rez A&#44; Fern&#225;ndez-Ant&#243;n Mart&#237;nez MC&#44; Su&#225;rez Fern&#225;ndez R&#46; N&#243;dulo malar en un var&#243;n inmunodeprimido&#46; Actas Dermosifiliogr&#46;2012&#59;103&#58;735-736&#46;</p>"
      ]
    ]
    "multimedia" => array:2 [
      0 => array:7 [
        "identificador" => "fig0005"
        "etiqueta" => "Figure 1"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr1.jpeg"
            "Alto" => 1213
            "Ancho" => 900
            "Tamanyo" => 210961
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Nonulcerated malar nodule&#46;</p>"
        ]
      ]
      1 => array:7 [
        "identificador" => "fig0010"
        "etiqueta" => "Figure 2"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr2.jpeg"
            "Alto" => 668
            "Ancho" => 900
            "Tamanyo" => 246606
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Hematoxylin-eosin&#44; original magnification &#215;100&#46;</p>"
        ]
      ]
    ]
    "bibliografia" => array:2 [
      "titulo" => "References"
      "seccion" => array:1 [
        0 => array:2 [
          "identificador" => "bibs0005"
          "bibliografiaReferencia" => array:7 [
            0 => array:3 [
              "identificador" => "bib0005"
              "etiqueta" => "1"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Actinomycosis"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "V&#46;K&#46; Wong"
                            1 => "T&#46;D&#46; Turmezei"
                            2 => "V&#46;C&#46; Weston"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "BMJ"
                        "fecha" => "2011"
                        "volumen" => "343"
                        "paginaInicial" => "d6099"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/21990282"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            1 => array:3 [
              "identificador" => "bib0010"
              "etiqueta" => "2"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Actinomicosis orocervicofacial&#46; Presentaci&#243;n de 5 casos"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "K&#46; Aguirrebengoa"
                            1 => "M&#46; Roma&#241;a"
                            2 => "L&#46; L&#243;pez"
                            3 => "J&#46; Mart&#237;n"
                            4 => "M&#46; Montejo"
                            5 => "P&#46; Gonz&#225;lez de Z&#225;rate"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Enferm Infecc Microbiol Clin"
                        "fecha" => "2002"
                        "volumen" => "20"
                        "paginaInicial" => "53"
                        "paginaFinal" => "56"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11886672"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            2 => array:3 [
              "identificador" => "bib0015"
              "etiqueta" => "3"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Primary cutaneous actinomycosis"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "D&#46; Patil"
                            1 => "B&#46; Siddaramappa"
                            2 => "B&#46;S&#46; Manjunathswamy"
                            3 => "A&#46;M&#46; Pandit"
                            4 => "S&#46; Dastikop"
                            5 => "C&#46; Fernandes"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1111/j.1365-4632.2008.03854.x"
                      "Revista" => array:6 [
                        "tituloSerie" => "Int J Dermatol"
                        "fecha" => "2008"
                        "volumen" => "47"
                        "paginaInicial" => "1271"
                        "paginaFinal" => "1273"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/19126014"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            3 => array:3 [
              "identificador" => "bib0020"
              "etiqueta" => "4"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Cutaneous actinomycosis&#58; the great mimicker"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "H&#46;A&#46; Ngow"
                            1 => "W&#46;N&#46; Wan Khairina"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1136/jcp.2008.063842"
                      "Revista" => array:5 [
                        "tituloSerie" => "J Clin Pathol"
                        "fecha" => "2009"
                        "volumen" => "62"
                        "paginaInicial" => "766"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/19638556"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            4 => array:3 [
              "identificador" => "bib0025"
              "etiqueta" => "5"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Cervicofacial actinomycosis resembling a ruptured cyst"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "V&#46; Cirillo-Hyland"
                            1 => "A&#46; Herzberg"
                            2 => "C&#46; Jaworsky"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "J Am Acad Dermatol"
                        "fecha" => "1993"
                        "volumen" => "29"
                        "paginaInicial" => "308"
                        "paginaFinal" => "311"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8340504"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            5 => array:3 [
              "identificador" => "bib0030"
              "etiqueta" => "6"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Abscesses from actinomyces infection&#58; why so difficult to diagnose&#63;"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "I&#46; Brook"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1586/eri.11.142"
                      "Revista" => array:6 [
                        "tituloSerie" => "Expert Rev Anti Infect Ther"
                        "fecha" => "2011"
                        "volumen" => "9"
                        "paginaInicial" => "1097"
                        "paginaFinal" => "1099"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/22114958"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            6 => array:3 [
              "identificador" => "bib0035"
              "etiqueta" => "7"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Actinomycosis&#58; diagnosis and management"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "I&#46; Brook"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1097/SMJ.0b013e3181864c1f"
                      "Revista" => array:6 [
                        "tituloSerie" => "South Med J"
                        "fecha" => "2008"
                        "volumen" => "101"
                        "paginaInicial" => "1019"
                        "paginaFinal" => "1023"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/18791528"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
          ]
        ]
      ]
    ]
  ]
  "idiomaDefecto" => "en"
  "url" => "/15782190/0000010300000008/v1_201304241323/S1578219012002557/v1_201304241323/en/main.assets"
  "Apartado" => array:4 [
    "identificador" => "6154"
    "tipo" => "SECCION"
    "en" => array:2 [
      "titulo" => "Case for Diagnosis"
      "idiomaDefecto" => true
    ]
    "idiomaDefecto" => "en"
  ]
  "PDF" => "https://static.elsevier.es/multimedia/15782190/0000010300000008/v1_201304241323/S1578219012002557/v1_201304241323/en/main.pdf?idApp=UINPBA000044&text.app=https://actasdermo.org/"
  "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219012002557?idApp=UINPBA000044"
]
Información del artículo
ISSN: 15782190
Idioma original: Inglés
Datos actualizados diariamente
año/Mes Html Pdf Total
2024 Noviembre 10 16 26
2024 Octubre 61 43 104
2024 Septiembre 91 38 129
2024 Agosto 103 76 179
2024 Julio 83 37 120
2024 Junio 83 39 122
2024 Mayo 70 40 110
2024 Abril 75 26 101
2024 Marzo 95 35 130
2024 Febrero 63 39 102
2024 Enero 51 40 91
2023 Diciembre 56 11 67
2023 Noviembre 63 23 86
2023 Octubre 52 23 75
2023 Septiembre 57 21 78
2023 Agosto 33 17 50
2023 Julio 78 36 114
2023 Junio 64 21 85
2023 Mayo 82 24 106
2023 Abril 58 19 77
2023 Marzo 75 22 97
2023 Febrero 48 20 68
2023 Enero 50 32 82
2022 Diciembre 50 37 87
2022 Noviembre 41 27 68
2022 Octubre 17 24 41
2022 Septiembre 25 38 63
2022 Agosto 20 28 48
2022 Julio 18 45 63
2022 Junio 15 33 48
2022 Mayo 37 29 66
2022 Abril 37 44 81
2022 Marzo 40 35 75
2022 Febrero 27 24 51
2022 Enero 33 38 71
2021 Diciembre 21 40 61
2021 Noviembre 37 45 82
2021 Octubre 33 59 92
2021 Septiembre 20 45 65
2021 Agosto 21 29 50
2021 Julio 36 37 73
2021 Junio 24 22 46
2021 Mayo 20 21 41
2021 Abril 76 46 122
2021 Marzo 48 30 78
2021 Febrero 44 20 64
2021 Enero 31 12 43
2020 Diciembre 25 17 42
2020 Noviembre 17 15 32
2020 Octubre 28 15 43
2020 Septiembre 44 7 51
2020 Agosto 27 18 45
2020 Julio 33 13 46
2020 Junio 38 28 66
2020 Mayo 22 21 43
2020 Abril 28 17 45
2020 Marzo 21 19 40
2020 Febrero 4 7 11
2020 Enero 3 1 4
2019 Diciembre 4 1 5
2019 Noviembre 4 0 4
2019 Octubre 0 2 2
2019 Agosto 4 5 9
2019 Julio 4 4 8
2019 Junio 4 8 12
2019 Mayo 6 14 20
2019 Abril 2 8 10
2019 Marzo 2 11 13
2019 Febrero 2 2 4
2019 Enero 2 4 6
2018 Diciembre 3 0 3
2018 Octubre 2 0 2
2018 Septiembre 3 0 3
2018 Mayo 0 7 7
2018 Abril 0 4 4
2018 Marzo 0 1 1
2018 Febrero 33 3 36
2018 Enero 41 6 47
2017 Diciembre 31 8 39
2017 Noviembre 32 6 38
2017 Octubre 33 4 37
2017 Septiembre 37 4 41
2017 Agosto 68 16 84
2017 Julio 35 11 46
2017 Junio 56 15 71
2017 Mayo 52 4 56
2017 Abril 36 10 46
2017 Marzo 29 30 59
2017 Febrero 35 11 46
2017 Enero 22 8 30
2016 Diciembre 45 5 50
2016 Noviembre 47 12 59
2016 Octubre 50 13 63
2016 Septiembre 41 8 49
2016 Agosto 44 18 62
2016 Julio 44 13 57
2016 Junio 7 15 22
2016 Mayo 11 17 28
2016 Abril 3 5 8
2016 Marzo 6 7 13
2016 Febrero 6 6 12
2016 Enero 4 2 6
2015 Diciembre 7 0 7
2015 Noviembre 17 4 21
2015 Octubre 16 3 19
2015 Septiembre 6 4 10
2015 Agosto 11 5 16
2015 Julio 58 6 64
2015 Junio 39 4 43
2015 Mayo 55 5 60
2015 Abril 39 12 51
2015 Marzo 46 9 55
2015 Febrero 39 6 45
2015 Enero 29 14 43
2014 Diciembre 31 7 38
2014 Noviembre 52 11 63
2014 Octubre 54 20 74
2014 Septiembre 13 0 13
2014 Agosto 18 4 22
2014 Julio 18 2 20
2014 Junio 30 2 32
2014 Mayo 38 9 47
2014 Abril 42 1 43
2014 Marzo 37 6 43
2014 Febrero 34 7 41
2014 Enero 21 2 23
2013 Diciembre 26 5 31
2013 Noviembre 25 4 29
2013 Octubre 17 3 20
2013 Septiembre 18 2 20
2013 Agosto 11 7 18
2013 Julio 13 7 20
2013 Junio 7 8 15
2013 Mayo 12 6 18
2013 Abril 14 10 24
2013 Marzo 19 5 24
2013 Febrero 28 6 34
2013 Enero 42 1 43
2012 Diciembre 32 6 38
2012 Noviembre 1 0 1
Mostrar todo

Siga este enlace para acceder al texto completo del artículo

Idiomas
Actas Dermo-Sifiliográficas
es en

¿Es usted profesional sanitario apto para prescribir o dispensar medicamentos?

Are you a health professional able to prescribe or dispense drugs?