Epidemiology of Contact Dermatitis in Spain. Results of the Spanish Surveillance System on Contact Allergies for the Year 2008
Epidemiología del eczema de contacto en España. Resultados de la Red Española de Vigilancia en Alergia de Contacto (REVAC) durante el año 2008
J. García-Gavína,
, J.C. Armario-Hitab, V. Fernández-Redondoa, J.M. Fernández-Vozmedianoc, J. Sánchez-Pérezd, J.F. Silvestree, W. Uterf, A.M. Giménez-Arnaug
Autor para correspondencia
a Servicio de Dermatología, Complejo Hospitalario Universitario, Facultad de Medicina, Santiago de Compostela, La Coruña, Spain
b Servicio de Dermatología, Hospital Punta de Europa, Algeciras, Universidad de Cádiz, Cádiz, Spain
c Servicio de Dermatología, Hospital Universitario de Puerto Real, Universidad de Cádiz, Cádiz, Spain
d Servicio de Dermatología, Hospital Universitario la Princesa, Madrid, Spain
e Sección de Dermatología, Hospital General Universitario de Alicante, Alicante, Spain
f Departamento de Informática Médica, Biometría y Epidemiología, Universidad de Erlangen-Núremberg, Erlangen, Germany
g Servicio de Dermatología, Hospital del Mar, Universitat Autònoma de Barcelona, Barcelona, Spain
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Resultados de la Red Española de Vigilancia en Alergia de Contacto (REVAC) durante el año 2008" ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "2010-09-09" "fechaAceptado" => "2010-10-17" "PalabrasClave" => array:2 [ "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Keywords" "identificador" => "xpalclavsec84851" "palabras" => array:6 [ 0 => "Contact dermatitis" 1 => "Epidemiology" 2 => "Allergic contact dermatitis" 3 => "Clinical research" 4 => "Skin patch tests" 5 => "Spanish standard series" ] ] ] "es" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palabras Clave" "identificador" => "xpalclavsec84850" "palabras" => array:7 [ 0 => "Eczema de contacto" 1 => "Epidemiología" 2 => "Dermatitis de contacto" 3 => "Dermatitis alérgica de contacto" 4 => "Investigación clínica" 5 => "Prueba epicutánea" 6 => "Serie estándar española" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "en" => array:2 [ "titulo" => "Abstract" "resumen" => "<span class="elsevierStyleSectionTitle">Background</span><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">The epidemiology of contact dermatitis can be analyzed using clinical data from skin allergy units.</p> <span class="elsevierStyleSectionTitle">Objectives</span><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">The aims of this study were to define the profile of patients attending a skin allergy unit and to determine the prevalence of the most common sensitizations in this population.</p> <span class="elsevierStyleSectionTitle">Material and methods</span><p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">Throughout 2008, a retrospective observational study was carried out in the 5 hospitals of the Spanish Surveillance System on Contact Allergies. All patients underwent skin patch tests with the Spanish standard series. The frequencies of sensitization were normalized for age and gender.</p> <span class="elsevierStyleSectionTitle">Results</span><p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">Data were gathered on 1161 patients. The 5 allergens that gave the most frequent positive reactions were nickel sulfate (25.88%), potassium dichromate (5.31%), cobalt chloride (5.10%), fragrance blends (4.64%), and balsam of Peru (4.44%). The least frequently detected reactions were to quinolone-clioquinol mix and sesquiterpene lactone mix. There was a 35% prevalence of sensitization to nickel among women.</p> <span class="elsevierStyleSectionTitle">Conclusions</span><p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">The profile of sensitizations in Spain is similar to that of other Southern European countries. Nickel sulfate continues to be the most prevalent allergen, particularly in women. The low prevalence of sensitization to quinolone-clioquinol mix and sesquiterpene lactone mix supports their exclusion of the Spanish series.</p>" ] "es" => array:2 [ "titulo" => "Resumen" "resumen" => "<span class="elsevierStyleSectionTitle">Introducción</span><p id="spar0030" class="elsevierStyleSimplePara elsevierViewall">El estudio epidemiológico del eczema de contacto puede realizarse mediante el análisis de los datos obtenidos a partir de la experiencia clínica de las unidades de alergia cutánea.</p> <span class="elsevierStyleSectionTitle">Objetivo</span><p id="spar0035" class="elsevierStyleSimplePara elsevierViewall">Determinar el perfil de los pacientes que acuden a una unidad de alergia cutánea y determinar la prevalencia de sensibilizaciones más frecuente en esta población.</p> <span class="elsevierStyleSectionTitle">Material y métodos</span><p id="spar0040" class="elsevierStyleSimplePara elsevierViewall">Estudio observacional retrospectivo de los 5 hospitales pertenecientes a la Red Española de Vigilancia de Alergia de Contacto (REVAC) durante el año 2008. Todos los pacientes fueron estudiados mediante pruebas epicutáneas con la serie estándar española. Las frecuencias de sensibilización se han estandarizado por sexo y edad. Resultados: Se recogieron datos de 1.161 pacientes. Los 5 alérgenos que presentaron positividades más frecuentemente fueron sulfato de níquel (25,88%), dicromato potásico (5,31%), cloruro de cobalto (5,10%), mezcla de fragancias (4,64%) y bálsamo del Perú (4,44%). Los alérgenos menos frecuentes fueron la mezcla de quinoleínas/clioquinol y la mezcla de lactonas sesquiterpénicas. En las mujeres la prevalencia de sensibilización al níquel fue del 35%.</p> <span class="elsevierStyleSectionTitle">Conclusiones</span><p id="spar0045" class="elsevierStyleSimplePara elsevierViewall">El perfil de sensibilizaciones de España es el esperado para un país del Sur de Europa. El sulfato de níquel sigue siendo el alérgeno más prevalente, siendo especialmente importante en mujeres. La mezcla de quinoleínas/clioquinol y la mezcla de lactonas sesquiterpénicas no han mostrado rentabilidad suficiente para su permanencia en la serie española.</p>" ] ] "bibliografia" => array:2 [ "titulo" => "References" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:30 [ 0 => array:3 [ "identificador" => "bib1" "etiqueta" => "1." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The epidemiology of contact allergy in the general population–prevalence and main findings" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "J.P. Thyssen" 1 => "A. Linneberg" 2 => "T. Menné" 3 => "J.D. 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| año/Mes | Html | Total | |
|---|---|---|---|
| 2024 Noviembre | 14 | 8 | 22 |
| 2024 Octubre | 72 | 43 | 115 |
| 2024 Septiembre | 63 | 27 | 90 |
| 2024 Agosto | 119 | 56 | 175 |
| 2024 Julio | 67 | 43 | 110 |
| 2024 Junio | 77 | 47 | 124 |
| 2024 Mayo | 74 | 25 | 99 |
| 2024 Abril | 70 | 26 | 96 |
| 2024 Marzo | 62 | 32 | 94 |
| 2024 Febrero | 61 | 38 | 99 |
| 2024 Enero | 42 | 32 | 74 |
| 2023 Diciembre | 51 | 36 | 87 |
| 2023 Noviembre | 62 | 39 | 101 |
| 2023 Octubre | 38 | 38 | 76 |
| 2023 Septiembre | 37 | 30 | 67 |
| 2023 Agosto | 28 | 18 | 46 |
| 2023 Julio | 27 | 35 | 62 |
| 2023 Junio | 38 | 25 | 63 |
| 2023 Mayo | 48 | 30 | 78 |
| 2023 Abril | 25 | 18 | 43 |
| 2023 Marzo | 22 | 19 | 41 |
| 2023 Febrero | 30 | 25 | 55 |
| 2023 Enero | 27 | 23 | 50 |
| 2022 Diciembre | 31 | 39 | 70 |
| 2022 Noviembre | 16 | 32 | 48 |
| 2022 Octubre | 27 | 18 | 45 |
| 2022 Septiembre | 43 | 36 | 79 |
| 2022 Agosto | 40 | 42 | 82 |
| 2022 Julio | 16 | 26 | 42 |
| 2022 Junio | 16 | 27 | 43 |
| 2022 Mayo | 26 | 39 | 65 |
| 2022 Abril | 25 | 42 | 67 |
| 2022 Marzo | 35 | 45 | 80 |
| 2022 Febrero | 30 | 32 | 62 |
| 2022 Enero | 23 | 46 | 69 |
| 2021 Diciembre | 20 | 42 | 62 |
| 2021 Noviembre | 30 | 42 | 72 |
| 2021 Octubre | 41 | 60 | 101 |
| 2021 Septiembre | 26 | 56 | 82 |
| 2021 Agosto | 29 | 35 | 64 |
| 2021 Julio | 18 | 31 | 49 |
| 2021 Junio | 48 | 38 | 86 |
| 2021 Mayo | 18 | 24 | 42 |
| 2021 Abril | 44 | 46 | 90 |
| 2021 Marzo | 45 | 18 | 63 |
| 2021 Febrero | 57 | 22 | 79 |
| 2021 Enero | 20 | 13 | 33 |
| 2020 Diciembre | 24 | 9 | 33 |
| 2020 Noviembre | 14 | 18 | 32 |
| 2020 Octubre | 29 | 9 | 38 |
| 2020 Septiembre | 24 | 18 | 42 |
| 2020 Agosto | 33 | 14 | 47 |
| 2020 Julio | 16 | 15 | 31 |
| 2020 Junio | 42 | 25 | 67 |
| 2020 Mayo | 27 | 27 | 54 |
| 2020 Abril | 19 | 13 | 32 |
| 2020 Marzo | 24 | 20 | 44 |
| 2020 Febrero | 3 | 5 | 8 |
| 2020 Enero | 0 | 4 | 4 |
| 2019 Diciembre | 0 | 8 | 8 |
| 2019 Noviembre | 0 | 2 | 2 |
| 2019 Octubre | 0 | 11 | 11 |
| 2019 Septiembre | 0 | 4 | 4 |
| 2019 Julio | 0 | 3 | 3 |
| 2019 Junio | 0 | 6 | 6 |
| 2019 Mayo | 1 | 48 | 49 |
| 2019 Abril | 0 | 6 | 6 |
| 2019 Marzo | 0 | 8 | 8 |
| 2018 Mayo | 0 | 11 | 11 |
| 2018 Marzo | 3 | 7 | 10 |
| 2018 Febrero | 9 | 5 | 14 |
| 2018 Enero | 19 | 7 | 26 |
| 2017 Diciembre | 21 | 9 | 30 |
| 2017 Noviembre | 25 | 10 | 35 |
| 2017 Octubre | 19 | 5 | 24 |
| 2017 Septiembre | 17 | 11 | 28 |
| 2017 Agosto | 36 | 8 | 44 |
| 2017 Julio | 27 | 6 | 33 |
| 2017 Junio | 36 | 9 | 45 |
| 2017 Mayo | 28 | 13 | 41 |
| 2017 Abril | 29 | 12 | 41 |
| 2017 Marzo | 29 | 35 | 64 |
| 2017 Febrero | 26 | 16 | 42 |
| 2017 Enero | 23 | 6 | 29 |
| 2016 Diciembre | 31 | 9 | 40 |
| 2016 Noviembre | 31 | 10 | 41 |
| 2016 Octubre | 16 | 16 | 32 |
| 2016 Septiembre | 72 | 7 | 79 |
| 2016 Agosto | 40 | 16 | 56 |
| 2016 Julio | 24 | 9 | 33 |
| 2016 Junio | 14 | 9 | 23 |
| 2016 Mayo | 6 | 9 | 15 |
| 2016 Abril | 2 | 7 | 9 |
| 2016 Marzo | 2 | 6 | 8 |
| 2016 Febrero | 8 | 5 | 13 |
| 2016 Enero | 9 | 2 | 11 |
| 2015 Diciembre | 8 | 0 | 8 |
| 2015 Noviembre | 8 | 1 | 9 |
| 2015 Octubre | 6 | 3 | 9 |
| 2015 Septiembre | 4 | 4 | 8 |
| 2015 Agosto | 10 | 3 | 13 |
| 2015 Julio | 21 | 9 | 30 |
| 2015 Junio | 32 | 7 | 39 |
| 2015 Mayo | 75 | 14 | 89 |
| 2015 Abril | 32 | 20 | 52 |
| 2015 Marzo | 25 | 15 | 40 |
| 2015 Febrero | 20 | 6 | 26 |
| 2015 Enero | 29 | 16 | 45 |
| 2014 Diciembre | 26 | 16 | 42 |
| 2014 Noviembre | 18 | 12 | 30 |
| 2014 Octubre | 37 | 18 | 55 |
| 2014 Septiembre | 21 | 16 | 37 |
| 2014 Agosto | 25 | 12 | 37 |
| 2014 Julio | 40 | 22 | 62 |
| 2014 Junio | 30 | 6 | 36 |
| 2014 Mayo | 45 | 13 | 58 |
| 2014 Abril | 30 | 14 | 44 |
| 2014 Marzo | 38 | 24 | 62 |
| 2014 Febrero | 30 | 12 | 42 |
| 2014 Enero | 31 | 14 | 45 |
| 2013 Diciembre | 47 | 11 | 58 |
| 2013 Noviembre | 26 | 31 | 57 |
| 2013 Octubre | 30 | 14 | 44 |
| 2013 Septiembre | 20 | 28 | 48 |
| 2013 Agosto | 24 | 23 | 47 |
| 2013 Julio | 39 | 22 | 61 |
| 2013 Junio | 29 | 35 | 64 |
| 2013 Mayo | 15 | 19 | 34 |
| 2013 Abril | 33 | 20 | 53 |
| 2013 Marzo | 34 | 16 | 50 |
| 2013 Febrero | 4 | 4 | 8 |
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