Practical dermatology
Clinical Guidelines for the Diagnosis and Treatment of Dermatitis Herpetiformis
Guía clínica de diagnóstico y tratamiento de la dermatitis herpetiforme
J.E. Herrero-González
Departamento de Dermatología, Hospital del Mar, Parc de Salut Mar, Institut Municipal d’Investigació Mèdica, Parc de Recerca Biomèdica de Barcelona, Barcelona, Spain
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Revisión de la evidencia y Consenso Delphi del Grupo de Psoriasis de la Academia Española de Dermatología y Venereología" ] ] "contieneResumen" => array:2 [ "en" => true "es" => true ] "contienePdf" => array:1 [ "en" => true ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "L. Puig, M. Ribera, J.M. Hernanz, I. Belinchón, J. Santos-Juanes, M. Linares, I. Querol, E. Colomé, G. Caballé" "autores" => array:9 [ 0 => array:2 [ "nombre" => "L." "apellidos" => "Puig" ] 1 => array:2 [ "nombre" => "M." "apellidos" => "Ribera" ] 2 => array:2 [ "nombre" => "J.M." "apellidos" => "Hernanz" ] 3 => array:2 [ "nombre" => "I." "apellidos" => "Belinchón" ] 4 => array:2 [ "nombre" => "J." "apellidos" => "Santos-Juanes" ] 5 => array:2 [ "nombre" => "M." "apellidos" => "Linares" ] 6 => array:2 [ "nombre" => "I." "apellidos" => "Querol" ] 7 => array:2 [ "nombre" => "E." "apellidos" => "Colomé" ] 8 => array:2 [ "nombre" => "G." "apellidos" => "Caballé" ] ] ] ] ] "idiomaDefecto" => "en" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219010707307?idApp=UINPBA000044" "url" => "/15782190/0000010100000010/v1_201304241533/S1578219010707307/v1_201304241533/en/main.assets" ] "itemAnterior" => array:18 [ "pii" => "S1578219010707289" "issn" => "15782190" "doi" => "10.1016/S1578-2190(10)70728-9" "estado" => "S300" "fechaPublicacion" => "2010-12-01" "aid" => "70728" "copyright" => "Academia Española de Dermatología y Venereología and Elsevier España, S.L." "documento" => "article" "crossmark" => 0 "subdocumento" => "fla" "cita" => "Actas Dermosifiliogr. 2010;101:817-9" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 2121 "formatos" => array:3 [ "EPUB" => 45 "HTML" => 1458 "PDF" => 618 ] ] "en" => array:9 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Opinion article</span>" "titulo" => "Syphilis, a Resurgent Disease" "tienePdf" => "en" "tieneTextoCompleto" => 0 "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "817" "paginaFinal" => "819" ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "El resurgir de la sífilis" ] ] "contienePdf" => array:1 [ "en" => true ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "M.J. Fuente" "autores" => array:1 [ 0 => array:2 [ "nombre" => "M.J." "apellidos" => "Fuente" ] ] ] ] ] "idiomaDefecto" => "en" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219010707289?idApp=UINPBA000044" "url" => "/15782190/0000010100000010/v1_201304241533/S1578219010707289/v1_201304241533/en/main.assets" ] "en" => array:15 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Practical dermatology</span>" "titulo" => "Clinical Guidelines for the Diagnosis and Treatment of Dermatitis Herpetiformis" "tieneTextoCompleto" => 0 "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "820" "paginaFinal" => "826" ] ] "autores" => array:1 [ 0 => array:3 [ "autoresLista" => "J.E. Herrero-González" "autores" => array:1 [ 0 => array:3 [ "nombre" => "J.E." "apellidos" => "Herrero-González" "email" => array:1 [ 0 => "jherrero@hospitaldelmar.org" ] ] ] "afiliaciones" => array:1 [ 0 => array:1 [ "entidad" => "Departamento de Dermatología, Hospital del Mar, Parc de Salut Mar, Institut Municipal d’Investigació Mèdica, Parc de Recerca Biomèdica de Barcelona, Barcelona, Spain" ] ] ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Guía clínica de diagnóstico y tratamiento de la dermatitis herpetiforme" ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "2010-03-24" "fechaAceptado" => "2010-06-10" "PalabrasClave" => array:2 [ "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Keywords" "identificador" => "xpalclavsec84822" "palabras" => array:5 [ 0 => "Celiac disease" 1 => "Dapsone" 2 => "Dermatitis herpetiformis" 3 => "Duhring disease" 4 => "Gluten" ] ] ] "es" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palabras clave" "identificador" => "xpalclavsec84823" "palabras" => array:5 [ 0 => "Celiaquía" 1 => "Dapsona" 2 => "Dermatitis herpetiforme" 3 => "Enfermedad de Duhring" 4 => "Gluten" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "en" => array:2 [ "titulo" => "Abstract" "resumen" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Dermatitis herpetiformis is an autoimmune blistering disease that appears as a cutaneous manifestation of gluten intolerance. It is one of a group of disorders that have gluten sensitivity in common, including celiac disease and gluten ataxia. Patients with dermatitis herpetiformis present with a pruritic papulovesicular rash on extensor surfaces and on the buttocks. Immunological studies demonstrate the presence of specific immunoglobulin (Ig) A antiendomysial and antitransglutaminase antibodies. The finding of granular deposits of IgA along the dermal-epidermal junction is pathognomonic of dermatitis herpetiformis. Treatment of dermatitis herpetiformis is based on a life-long, strict gluten-free diet, which improves all clinical aspects of gluten sensitivity, and dapsone, a drug that is only effective for the skin manifestations.</p>" ] "es" => array:2 [ "titulo" => "Resumen" "resumen" => "<p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">La dermatitis herpetiforme es una enfermedad ampollosa autoinmune que aparece como expresión cutánea de la intolerancia al gluten. Forma parte de un abanico de patologías que tienen en común la sensibilidad a este componente, entre las cuales se encuentra la celiaquía y la ataxia por gluten. Los pacientes con dermatitis herpetiforme presentan una erupción papulovesicular pruriginosa de predominio en superficies de extensión y nalgas. El estudio inmunológico demuestra la presencia de anticuerpos específicos IgA antiendomisio y antitransglutaminasa. El hallazgo de depósitos granulares de IgA en la unión dermoepidérmica es patognomónico de la dermatitis herpetiforme. El tratamiento se basa en dos pilares: mantener indefinidamente una dieta estricta libre de este componente (la cual mejora todas las formas clínicas de la sensibilidad al gluten) y la dapsona, fármaco que es eficaz solo para las manifestaciones cutáneas.</p>" ] ] "bibliografia" => array:2 [ "titulo" => "References" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:43 [ 0 => array:3 [ "identificador" => "bib1" "etiqueta" => "1." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Small-bowel changes in dermatitis herpetiformis" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "J. Marks" 1 => "S. Shuster" 2 => "A. 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| año/Mes | Html | Total | |
|---|---|---|---|
| 2024 Noviembre | 14 | 11 | 25 |
| 2024 Octubre | 82 | 58 | 140 |
| 2024 Septiembre | 85 | 60 | 145 |
| 2024 Agosto | 102 | 79 | 181 |
| 2024 Julio | 79 | 41 | 120 |
| 2024 Junio | 76 | 44 | 120 |
| 2024 Mayo | 66 | 43 | 109 |
| 2024 Abril | 57 | 36 | 93 |
| 2024 Marzo | 64 | 47 | 111 |
| 2024 Febrero | 40 | 33 | 73 |
| 2024 Enero | 51 | 43 | 94 |
| 2023 Diciembre | 64 | 62 | 126 |
| 2023 Noviembre | 62 | 43 | 105 |
| 2023 Octubre | 37 | 35 | 72 |
| 2023 Septiembre | 43 | 26 | 69 |
| 2023 Agosto | 24 | 32 | 56 |
| 2023 Julio | 43 | 52 | 95 |
| 2023 Junio | 48 | 30 | 78 |
| 2023 Mayo | 56 | 29 | 85 |
| 2023 Abril | 45 | 28 | 73 |
| 2023 Marzo | 27 | 20 | 47 |
| 2023 Febrero | 20 | 22 | 42 |
| 2023 Enero | 30 | 37 | 67 |
| 2022 Diciembre | 33 | 53 | 86 |
| 2022 Noviembre | 19 | 23 | 42 |
| 2022 Octubre | 16 | 18 | 34 |
| 2022 Septiembre | 21 | 28 | 49 |
| 2022 Agosto | 22 | 28 | 50 |
| 2022 Julio | 18 | 30 | 48 |
| 2022 Junio | 17 | 18 | 35 |
| 2022 Mayo | 30 | 45 | 75 |
| 2022 Abril | 60 | 48 | 108 |
| 2022 Marzo | 74 | 53 | 127 |
| 2022 Febrero | 78 | 39 | 117 |
| 2022 Enero | 51 | 52 | 103 |
| 2021 Diciembre | 36 | 46 | 82 |
| 2021 Noviembre | 42 | 46 | 88 |
| 2021 Octubre | 61 | 63 | 124 |
| 2021 Septiembre | 42 | 45 | 87 |
| 2021 Agosto | 80 | 38 | 118 |
| 2021 Julio | 54 | 31 | 85 |
| 2021 Junio | 43 | 36 | 79 |
| 2021 Mayo | 40 | 31 | 71 |
| 2021 Abril | 80 | 65 | 145 |
| 2021 Marzo | 105 | 23 | 128 |
| 2021 Febrero | 86 | 29 | 115 |
| 2021 Enero | 64 | 28 | 92 |
| 2020 Diciembre | 27 | 13 | 40 |
| 2020 Noviembre | 26 | 24 | 50 |
| 2020 Octubre | 40 | 9 | 49 |
| 2020 Septiembre | 35 | 9 | 44 |
| 2020 Agosto | 41 | 26 | 67 |
| 2020 Julio | 29 | 16 | 45 |
| 2020 Junio | 20 | 24 | 44 |
| 2020 Mayo | 30 | 12 | 42 |
| 2020 Abril | 15 | 21 | 36 |
| 2020 Marzo | 23 | 25 | 48 |
| 2020 Febrero | 4 | 4 | 8 |
| 2020 Enero | 0 | 2 | 2 |
| 2019 Diciembre | 0 | 18 | 18 |
| 2019 Noviembre | 0 | 11 | 11 |
| 2019 Octubre | 0 | 14 | 14 |
| 2019 Septiembre | 0 | 6 | 6 |
| 2019 Agosto | 0 | 7 | 7 |
| 2019 Julio | 0 | 13 | 13 |
| 2019 Junio | 0 | 11 | 11 |
| 2019 Mayo | 1 | 43 | 44 |
| 2019 Abril | 0 | 3 | 3 |
| 2019 Marzo | 0 | 7 | 7 |
| 2018 Mayo | 0 | 45 | 45 |
| 2018 Marzo | 1 | 2 | 3 |
| 2018 Febrero | 11 | 7 | 18 |
| 2018 Enero | 27 | 4 | 31 |
| 2017 Diciembre | 15 | 10 | 25 |
| 2017 Noviembre | 18 | 5 | 23 |
| 2017 Octubre | 17 | 6 | 23 |
| 2017 Septiembre | 17 | 7 | 24 |
| 2017 Agosto | 18 | 5 | 23 |
| 2017 Julio | 16 | 3 | 19 |
| 2017 Junio | 20 | 14 | 34 |
| 2017 Mayo | 20 | 8 | 28 |
| 2017 Abril | 23 | 7 | 30 |
| 2017 Marzo | 11 | 34 | 45 |
| 2017 Febrero | 20 | 14 | 34 |
| 2017 Enero | 12 | 15 | 27 |
| 2016 Diciembre | 27 | 12 | 39 |
| 2016 Noviembre | 26 | 10 | 36 |
| 2016 Octubre | 18 | 22 | 40 |
| 2016 Septiembre | 34 | 6 | 40 |
| 2016 Agosto | 31 | 12 | 43 |
| 2016 Julio | 33 | 5 | 38 |
| 2016 Junio | 10 | 13 | 23 |
| 2016 Mayo | 4 | 12 | 16 |
| 2016 Abril | 2 | 23 | 25 |
| 2016 Marzo | 8 | 7 | 15 |
| 2016 Febrero | 11 | 11 | 22 |
| 2016 Enero | 8 | 12 | 20 |
| 2015 Diciembre | 9 | 5 | 14 |
| 2015 Noviembre | 13 | 10 | 23 |
| 2015 Octubre | 7 | 10 | 17 |
| 2015 Septiembre | 5 | 5 | 10 |
| 2015 Agosto | 15 | 3 | 18 |
| 2015 Julio | 35 | 21 | 56 |
| 2015 Junio | 44 | 32 | 76 |
| 2015 Mayo | 75 | 25 | 100 |
| 2015 Abril | 34 | 19 | 53 |
| 2015 Marzo | 28 | 17 | 45 |
| 2015 Febrero | 13 | 13 | 26 |
| 2015 Enero | 14 | 15 | 29 |
| 2014 Diciembre | 23 | 13 | 36 |
| 2014 Noviembre | 22 | 24 | 46 |
| 2014 Octubre | 35 | 15 | 50 |
| 2014 Septiembre | 30 | 15 | 45 |
| 2014 Agosto | 34 | 16 | 50 |
| 2014 Julio | 43 | 15 | 58 |
| 2014 Junio | 42 | 14 | 56 |
| 2014 Mayo | 41 | 12 | 53 |
| 2014 Abril | 30 | 9 | 39 |
| 2014 Marzo | 41 | 18 | 59 |
| 2014 Febrero | 26 | 17 | 43 |
| 2014 Enero | 27 | 18 | 45 |
| 2013 Diciembre | 38 | 23 | 61 |
| 2013 Noviembre | 25 | 21 | 46 |
| 2013 Octubre | 31 | 16 | 47 |
| 2013 Septiembre | 22 | 40 | 62 |
| 2013 Agosto | 22 | 38 | 60 |
| 2013 Julio | 29 | 44 | 73 |
| 2013 Junio | 31 | 38 | 69 |
| 2013 Mayo | 31 | 37 | 68 |
| 2013 Abril | 25 | 25 | 50 |
| 2013 Marzo | 20 | 30 | 50 |
| 2013 Febrero | 15 | 14 | 29 |
| 2013 Enero | 2 | 1 | 3 |
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