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        "resumen" => "<span class="elsevierStyleSectionTitle">Background</span><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Recent years have seen an increase in the off-label use of photodynamic therapy for the treatment of a variety of skin diseases&#46; Plaque-phase mycosis fungoides is among the most promising possibilities for the use of this treatment&#46;</p> <span class="elsevierStyleSectionTitle">Objectives</span><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">To evaluate the treatment of plaque-phase mycosis fungoides with photodynamic therapy and compare the results obtained using fluorescence photography&#46;</p> <span class="elsevierStyleSectionTitle">Material and methods</span><p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">We performed a prospective&#44; descriptive&#44; observational study&#46; Twelve patients with 24 lesions were treated with topical methyl aminolevulinate &#40;MAL&#41; under an occlusive dressing for 3 hours&#44; followed by 8 minutes of red light &#40;630 nm&#44; 37 J&#47; cm<span class="elsevierStyleSup">2</span>&#59; Aktilite&#41;&#46;</p> <span class="elsevierStyleSectionTitle">Results</span><p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">Six patients had a complete response&#44; 5 a partial response&#44; and 1 did not respond to treatment&#46; A mean of 5&#46;7 sessions was applied and no side effects were reported&#46; Treatment tolerance was excellent&#46;</p> <span class="elsevierStyleSectionTitle">Conclusions</span><p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">Photodynamic therapy with MAL appears to be a good treatment option for patients with plaque-phase mycosis fungoides with a small number of lesions&#46;</p>"
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        "resumen" => "<span class="elsevierStyleSectionTitle">Introducci&#243;n</span><p id="spar0030" class="elsevierStyleSimplePara elsevierViewall">La terapia fotodin&#225;mica &#40;TFD&#41; est&#225; siendo desarrollada en los &#250;ltimos a&#241;os en dermatosis diferentes de las aprobadas para su uso&#46; Entre todas ellas&#44; la micosis fungoide &#40;MF&#41; en estadio de placas es una de las m&#225;s prometedoras&#46;</p> <span class="elsevierStyleSectionTitle">Objetivos</span><p id="spar0035" class="elsevierStyleSimplePara elsevierViewall">Evaluar los resultados en el tratamiento de la MF en placas con TFD y correlacionarlos con la fotograf&#237;a de fluorescencia&#46;</p> <span class="elsevierStyleSectionTitle">Material y m&#233;todos</span><p id="spar0040" class="elsevierStyleSimplePara elsevierViewall">Llevamos a cabo un estudio prospectivo&#44; descriptivo y observacional&#46; Se seleccionaron un total de 12 pacientes con 24 lesiones que fueron tratados con metilaminolevulinato &#40;MAL&#41; t&#243;pico ocluido tres horas y luz roja &#40;630 nm&#44; 37 J&#47;cm<span class="elsevierStyleSup">2</span>&#44; 8 min&#44; Aktilite<span class="elsevierStyleSup">&#174;</span>&#41;&#46;</p> <span class="elsevierStyleSectionTitle">Resultados</span><p id="spar0045" class="elsevierStyleSimplePara elsevierViewall">Un total de 6 pacientes obtuvo respuesta completa&#44; 5 pacientes alcanzaron respuesta parcial y uno no respondi&#243; al tratamiento&#46; La media de sesiones aplicadas fue de 5&#44;7 y no se recopilaron efectos secundarios&#46; La tolerancia fue excelente&#46;</p> <span class="elsevierStyleSectionTitle">Conclusiones</span><p id="spar0050" class="elsevierStyleSimplePara elsevierViewall">La TFD con MAL parece una buena alternativa terap&#233;utica para los pacientes con MF en placas con escaso n&#250;mero de lesiones&#46;</p>"
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                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Otras indicaciones dermatol&#243;gicas del ALAPDT"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "E&#46;M&#46; Welch"
                            1 => "K&#46; Kelly"
                          ]
                        ]
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                  ]
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                    0 => array:2 [
                      "titulo" => "Photodynamic therapy of nonmelanoma malignant tumours of the skin using topical delta-aminolaevulinic acid sensitization and laser irradiation"
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                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
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                            2 => "D&#46; Killander"
                            3 => "I&#46; Wang"
                            4 => "U&#46; Stenram"
                            5 => "S&#46; Aderson-Engels"
                          ]
                        ]
                      ]
                    ]
                  ]
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                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Br J Dermatol"
                        "fecha" => "1994"
                        "volumen" => "130"
                        "paginaInicial" => "743"
                        "paginaFinal" => "751"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8011500"
                            "web" => "Medline"
                          ]
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                    ]
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                ]
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                          "autores" => array:4 [
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                            2 => "L&#46; Cerroni"
                            3 => "H&#46; Kerl"
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                        ]
                      ]
                    ]
                  ]
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                        "tituloSerie" => "J Am Acad Dermatol"
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                        "paginaInicial" => "678"
                        "paginaFinal" => "680"
                        "link" => array:1 [
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                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8089302"
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                  ]
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                      "Revista" => array:5 [
                        "tituloSerie" => "J Am Acad Dermatol"
                        "fecha" => "1995"
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                        "paginaInicial" => "541"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/7657888"
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                      "Revista" => array:4 [
                        "tituloSerie" => "J Dermatol Sci"
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                        "paginaInicial" => "229"
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                    ]
                  ]
                ]
              ]
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                          "autores" => array:3 [
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                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Acta Oftalm Scan"
                        "fecha" => "1999"
                        "volumen" => "77"
                        "paginaInicial" => "182"
                        "paginaFinal" => "188"
                      ]
                    ]
                  ]
                ]
              ]
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                          "etal" => true
                          "autores" => array:6 [
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                            2 => "J&#46; Tamir"
                            3 => "E&#46; Winkler"
                            4 => "H&#46; Trau"
                            5 => "Z&#46; Malik"
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                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
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                        "tituloSerie" => "Dermatol Surg"
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                        "paginaFinal" => "769"
                        "link" => array:1 [
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                          "autores" => array:3 [
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                          0 => array:2 [
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                        "link" => array:1 [
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Original Article
Plaque-Phase Mycosis Fungoides Treated with Photodynamic Therapy: Results from 12 Patients
Micosis fungoide en fase de placas tratada con terapia fotodinámica: resultados en 12 pacientes
M. Fernández-Guarino
Autor para correspondencia
montsefdez@msn.com

Corresponding author.
, A. Harto, B. Pérez-García, C. Montull, E. De Las Heras, P. Jaén
Servicio de Dermatología, Hospital Universitario Ramón y Cajal, Universidad de Alcalá, Madrid, Spain
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            2 => "Methyl aminolevulinate"
          ]
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        0 => array:4 [
          "clase" => "keyword"
          "titulo" => "Palabras clave"
          "identificador" => "xpalclavsec84806"
          "palabras" => array:3 [
            0 => "Micosis fungoide"
            1 => "Terapia fotodin&#225;mica"
            2 => "Metilaminolevul&#237;nico"
          ]
        ]
      ]
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      "en" => array:2 [
        "titulo" => "Abstract"
        "resumen" => "<span class="elsevierStyleSectionTitle">Background</span><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Recent years have seen an increase in the off-label use of photodynamic therapy for the treatment of a variety of skin diseases&#46; Plaque-phase mycosis fungoides is among the most promising possibilities for the use of this treatment&#46;</p> <span class="elsevierStyleSectionTitle">Objectives</span><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">To evaluate the treatment of plaque-phase mycosis fungoides with photodynamic therapy and compare the results obtained using fluorescence photography&#46;</p> <span class="elsevierStyleSectionTitle">Material and methods</span><p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">We performed a prospective&#44; descriptive&#44; observational study&#46; Twelve patients with 24 lesions were treated with topical methyl aminolevulinate &#40;MAL&#41; under an occlusive dressing for 3 hours&#44; followed by 8 minutes of red light &#40;630 nm&#44; 37 J&#47; cm<span class="elsevierStyleSup">2</span>&#59; Aktilite&#41;&#46;</p> <span class="elsevierStyleSectionTitle">Results</span><p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">Six patients had a complete response&#44; 5 a partial response&#44; and 1 did not respond to treatment&#46; A mean of 5&#46;7 sessions was applied and no side effects were reported&#46; Treatment tolerance was excellent&#46;</p> <span class="elsevierStyleSectionTitle">Conclusions</span><p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">Photodynamic therapy with MAL appears to be a good treatment option for patients with plaque-phase mycosis fungoides with a small number of lesions&#46;</p>"
      ]
      "es" => array:2 [
        "titulo" => "Resumen"
        "resumen" => "<span class="elsevierStyleSectionTitle">Introducci&#243;n</span><p id="spar0030" class="elsevierStyleSimplePara elsevierViewall">La terapia fotodin&#225;mica &#40;TFD&#41; est&#225; siendo desarrollada en los &#250;ltimos a&#241;os en dermatosis diferentes de las aprobadas para su uso&#46; Entre todas ellas&#44; la micosis fungoide &#40;MF&#41; en estadio de placas es una de las m&#225;s prometedoras&#46;</p> <span class="elsevierStyleSectionTitle">Objetivos</span><p id="spar0035" class="elsevierStyleSimplePara elsevierViewall">Evaluar los resultados en el tratamiento de la MF en placas con TFD y correlacionarlos con la fotograf&#237;a de fluorescencia&#46;</p> <span class="elsevierStyleSectionTitle">Material y m&#233;todos</span><p id="spar0040" class="elsevierStyleSimplePara elsevierViewall">Llevamos a cabo un estudio prospectivo&#44; descriptivo y observacional&#46; Se seleccionaron un total de 12 pacientes con 24 lesiones que fueron tratados con metilaminolevulinato &#40;MAL&#41; t&#243;pico ocluido tres horas y luz roja &#40;630 nm&#44; 37 J&#47;cm<span class="elsevierStyleSup">2</span>&#44; 8 min&#44; Aktilite<span class="elsevierStyleSup">&#174;</span>&#41;&#46;</p> <span class="elsevierStyleSectionTitle">Resultados</span><p id="spar0045" class="elsevierStyleSimplePara elsevierViewall">Un total de 6 pacientes obtuvo respuesta completa&#44; 5 pacientes alcanzaron respuesta parcial y uno no respondi&#243; al tratamiento&#46; La media de sesiones aplicadas fue de 5&#44;7 y no se recopilaron efectos secundarios&#46; La tolerancia fue excelente&#46;</p> <span class="elsevierStyleSectionTitle">Conclusiones</span><p id="spar0050" class="elsevierStyleSimplePara elsevierViewall">La TFD con MAL parece una buena alternativa terap&#233;utica para los pacientes con MF en placas con escaso n&#250;mero de lesiones&#46;</p>"
      ]
    ]
    "bibliografia" => array:2 [
      "titulo" => "References"
      "seccion" => array:1 [
        0 => array:2 [
          "identificador" => "bibs0005"
          "bibliografiaReferencia" => array:17 [
            0 => array:3 [
              "identificador" => "bib1"
              "etiqueta" => "1&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Otras indicaciones dermatol&#243;gicas del ALAPDT"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "E&#46;M&#46; Welch"
                            1 => "K&#46; Kelly"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "LibroEditado" => array:4 [
                        "titulo" => "Terapia fotodin&#225;mica Primera"
                        "paginaInicial" => "89"
                        "paginaFinal" => "101"
                        "serieFecha" => "2006"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            1 => array:3 [
              "identificador" => "bib2"
              "etiqueta" => "2&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Photodynamic therapy of nonmelanoma malignant tumours of the skin using topical delta-aminolaevulinic acid sensitization and laser irradiation"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "K&#46; Svanberg"
                            1 => "T&#46; Andersson"
                            2 => "D&#46; Killander"
                            3 => "I&#46; Wang"
                            4 => "U&#46; Stenram"
                            5 => "S&#46; Aderson-Engels"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Br J Dermatol"
                        "fecha" => "1994"
                        "volumen" => "130"
                        "paginaInicial" => "743"
                        "paginaFinal" => "751"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8011500"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            2 => array:3 [
              "identificador" => "bib3"
              "etiqueta" => "3&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Photodynamic therapy for mycosis fungoides after photosensitization with 5-aminolaevulinic acid"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "P&#46; Wolf"
                            1 => "R&#46; Fink-Puches"
                            2 => "L&#46; Cerroni"
                            3 => "H&#46; Kerl"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "J Am Acad Dermatol"
                        "fecha" => "1994"
                        "volumen" => "31"
                        "paginaInicial" => "678"
                        "paginaFinal" => "680"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8089302"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            3 => array:3 [
              "identificador" => "bib4"
              "etiqueta" => "4&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Photodynamic therapy for mycosis fungoides after topical photosensitization with 5-aminolaevulinic acid"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "R&#46; Ammann"
                            1 => "Th&#46; Hunziker"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "J Am Acad Dermatol"
                        "fecha" => "1995"
                        "volumen" => "33"
                        "paginaInicial" => "541"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/7657888"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            4 => array:3 [
              "identificador" => "bib5"
              "etiqueta" => "5&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Topical 5-aminolaevulinic acid based photodynamic therapy for mycosis fungoides a study of cell proliferation an apoptosis before and after therapy"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "D&#46;W&#46; Edstrom"
                            1 => "A&#46;W&#46; Ros"
                            2 => "A&#46; Parvit"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:4 [
                        "tituloSerie" => "J Dermatol Sci"
                        "fecha" => "1998"
                        "volumen" => "16"
                        "paginaInicial" => "229"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            5 => array:3 [
              "identificador" => "bib6"
              "etiqueta" => "6&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Photodynamic therapy utilizing delta aminolevulinic acid in non-melanoma skins malignancies of the eyelid and periocular skin"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "I&#46; Wang"
                            1 => "B&#46; Bauer"
                            2 => "S&#46; Anderson-Engels"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Acta Oftalm Scan"
                        "fecha" => "1999"
                        "volumen" => "77"
                        "paginaInicial" => "182"
                        "paginaFinal" => "188"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            6 => array:3 [
              "identificador" => "bib7"
              "etiqueta" => "7&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Photodynamic therapy of cutaneous lymphoma using 5-aminolevulinic acid topical application"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "A&#46; Orestein"
                            1 => "J&#46; Haik"
                            2 => "J&#46; Tamir"
                            3 => "E&#46; Winkler"
                            4 => "H&#46; Trau"
                            5 => "Z&#46; Malik"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Dermatol Surg"
                        "fecha" => "2000"
                        "volumen" => "26"
                        "paginaInicial" => "765"
                        "paginaFinal" => "769"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10940064"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            7 => array:3 [
              "identificador" => "bib8"
              "etiqueta" => "8&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Topical 5-aminolvulinic acid photodynamic therapy for tumour-stage mycosis fungoides"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "T&#46; Markham"
                            1 => "K&#46; Sheehan"
                            2 => "P&#46; Collins"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Br J Dermatol"
                        "fecha" => "2001"
                        "volumen" => "144"
                        "paginaInicial" => "1262"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11422054"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            8 => array:3 [
              "identificador" => "bib9"
              "etiqueta" => "9&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Photodynamic therapy with topical 5-aminolvulinic acid for mycosis fungoides&#58; clinical and histological response"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "D&#46;W&#46; Edstrom"
                            1 => "A&#46; Portwit"
                            2 => "A&#46;M&#46; Ros"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Acta Derm Venereol"
                        "fecha" => "2001"
                        "volumen" => "81"
                        "paginaInicial" => "184"
                        "paginaFinal" => "188"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11558874"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            9 => array:3 [
              "identificador" => "bib10"
              "etiqueta" => "10&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Remission of a cutaneous mycosis fungoides after topical 5-ALA sensitization and photodynamic therapy in a patient with advanced HIV-infection"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "V&#46; Paech"
                            1 => "T&#46; Lorenzen"
                            2 => "Stoehr"
                            3 => "K&#46; Lange"
                            4 => "H&#46; Merz"
                            5 => "W&#46;N&#46; Meigel"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Eur J Med Res"
                        "fecha" => "2002"
                        "volumen" => "7"
                        "paginaInicial" => "477"
                        "paginaFinal" => "479"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12568975"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            10 => array:3 [
              "identificador" => "bib11"
              "etiqueta" => "11&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Topical 5-ALA therapy for the treatment of cutaneous T-cell lymphoma"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "J&#46;A&#46; Leman"
                            1 => "D&#46;C&#46; Dick"
                            2 => "C&#46;A&#46; Morton"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Clin Exp Dermatol"
                        "fecha" => "2002"
                        "volumen" => "27"
                        "paginaInicial" => "516"
                        "paginaFinal" => "518"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12372098"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            11 => array:3 [
              "identificador" => "bib12"
              "etiqueta" => "12&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Topical photodynamic therapy for patients with therapy-resistant lesions of cutaneous T-cell lymphoma"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "E&#46;A&#46; Coors"
                            1 => "P&#46; von den Driesch"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1016/S0190"
                      "Revista" => array:6 [
                        "tituloSerie" => "J Am Acad Dermatol"
                        "fecha" => "2004"
                        "volumen" => "50"
                        "paginaInicial" => "363"
                        "paginaFinal" => "367"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/14988676"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            12 => array:3 [
              "identificador" => "bib13"
              "etiqueta" => "13&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Photodynamic therapy with methylaminolevulinate as a valuable treatment option for unilesional cutaneous T- cell lymphoma"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "C&#46; Zane"
                            1 => "M&#46; Venturini"
                            2 => "R&#46; Sala"
                            3 => "P&#46; Calzavara-Pinton"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Photodermatol Photoinmunol Photomed"
                        "fecha" => "2006"
                        "volumen" => "22"
                        "paginaInicial" => "254"
                        "paginaFinal" => "258"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            13 => array:3 [
              "identificador" => "bib14"
              "etiqueta" => "14&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Topical 5-aminolaevulinic acid photodynamic therapy for the treatment of unilesional mycosis fungoides&#44; a report of two cases and review of the literature"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "E&#46; D&#237;ez-Recio"
                            1 => "B&#46; Zambrano"
                            2 => "M&#46;L&#46; Alonso"
                            3 => "E&#46; De Eusebio"
                            4 => "M&#46; Mart&#237;n"
                            5 => "J&#46; Cuevas"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1111/j.1365-4632.2008.03177.x"
                      "Revista" => array:6 [
                        "tituloSerie" => "Int J Dermatol"
                        "fecha" => "2008"
                        "volumen" => "47"
                        "paginaInicial" => "410"
                        "paginaFinal" => "413"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/18377612"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            14 => array:3 [
              "identificador" => "bib15"
              "etiqueta" => "15&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "In vitro and in vivo effects of photodynamic therapy in cutaneous T cell lymphoma"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "W&#46; Boehnke"
                            1 => "R&#46; Koning"
                            2 => "A&#46; Ruck"
                            3 => "R&#46; Kaufmann"
                            4 => "W&#46; Sterry"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Acta Dermvenereol"
                        "fecha" => "1994"
                        "volumen" => "74"
                        "paginaInicial" => "201"
                        "paginaFinal" => "205"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            15 => array:3 [
              "identificador" => "bib16"
              "etiqueta" => "16&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "The role of transferrin receptor &#40;CD71&#41; in photodynamic therapy of activated and malignant lymphocytes using the hem precursor delta-aminolaevulinic acid &#40;ALA&#41;"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "K&#46; Rittenhouse-Diakun"
                            1 => "H&#46; Van Leengoed"
                            2 => "J&#46; Morgan"
                            3 => "E&#46; Hryhorenko"
                            4 => "G&#46; Paszkiewicz"
                            5 => "J&#46;E&#46; Whitaker"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Photochem Photobiol"
                        "fecha" => "1995"
                        "volumen" => "61"
                        "paginaInicial" => "523"
                        "paginaFinal" => "528"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/7770514"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            16 => array:3 [
              "identificador" => "bib17"
              "etiqueta" => "17&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Efficacy and tolerability of currently available therapies for the mycosis fungoides and Sezar syndrome variants of cutaneous T-cell lymphoma"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "S&#46;J&#46; Whittaker"
                            1 => "F&#46;M&#46; Foss"
                          ]
                        ]
                      ]
                    ]
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                        "tituloSerie" => "Cancer Treat Rev"
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                        "volumen" => "33"
                        "paginaInicial" => "146"
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    "identificador" => "6256"
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Información del artículo
ISSN: 15782190
Idioma original: Inglés
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