Controversies in Dermatology
Primary Cutaneous CD30+ Lymphoproliferative Disorders
Síndrome linfoproliferativo CD30+ cutáneo primario
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This group includes lymphomatoid papulosis and CD30<span class="elsevierStyleSup">+</span> anaplastic large-cell lymphoma; these 2 entities are the extremes of a spectrum with numerous intermediate varieties in which it is not possible to establish a clear diagnosis based on clinical and histopathologic criteria. CD30<span class="elsevierStyleSup">+</span> lymphoproliferative disorders must be differentiated from other lymphoproliferative diseases with CD30<span class="elsevierStyleSup">+</span> cells in the tumor infiltrates, such as mycosis fungoides or Hodgkin disease, and also from other inflammatory conditions or nonhematological neoplasms that can include this cell type, such as pityriasis lichenoides et varioliformis acuta or certain mesenchymal tumors (CD30<span class="elsevierStyleSup">+</span> pseudolymphomas). In contrast to their systemic homologues, which arise in the lymph nodes, CD30<span class="elsevierStyleSup">+</span> lymphoproliferative disorders generally have a good prognosis. It is very important to exclude the presence of a lymphoma of systemic origin with extralymphatic spread, as the prognosis and treatment are different.</p>" ] "es" => array:2 [ "titulo" => "Resumen" "resumen" => "<p class="elsevierStyleSimplePara elsevierViewall">El segundo grupo más frecuente de linfomas cutáneos de células T son los síndromes linfoproliferativos (SLP) CD30+, por detrás del grupo de la micosis fungoide (MF) y sus variantes. Estos engloban la papulosis linfomatoide y los linfomas anaplásicos de células grandes CD30+, polos de un espectro que dejan en su zona central casos intermedios, donde no se puede establecer con seguridad un diagnóstico en base a criterios clínicos e histopatológicos.</p><p class="elsevierStyleSimplePara elsevierViewall">Los SLP CD30+ deben diferenciarse de otros procesos linfoproliferativos que pueden presentar células CD30+ en sus infiltrados tumorales, como la propia MF o la enfermedad de Hodgkin, y también de otras entidades inflamatorias o neoplasias no hematológicas que presenten estas células, como es el caso de la pitiriasis liquenoide y varioliforme aguda o determinados tumores mesenquimales («pseudolinfomas CD30+»).</p><p class="elsevierStyleSimplePara elsevierViewall">En general, el pronóstico de estos SLP CD30+ es favorable, lo que les diferencia de sus homólogos sistémicos, de origen ganglionar. 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| año/Mes | Html | Total | |
|---|---|---|---|
| 2024 Noviembre | 5 | 12 | 17 |
| 2024 Octubre | 65 | 54 | 119 |
| 2024 Septiembre | 59 | 27 | 86 |
| 2024 Agosto | 85 | 61 | 146 |
| 2024 Julio | 66 | 34 | 100 |
| 2024 Junio | 72 | 44 | 116 |
| 2024 Mayo | 52 | 39 | 91 |
| 2024 Abril | 55 | 31 | 86 |
| 2024 Marzo | 47 | 34 | 81 |
| 2024 Febrero | 56 | 41 | 97 |
| 2024 Enero | 45 | 42 | 87 |
| 2023 Diciembre | 53 | 36 | 89 |
| 2023 Noviembre | 45 | 26 | 71 |
| 2023 Octubre | 46 | 30 | 76 |
| 2023 Septiembre | 47 | 27 | 74 |
| 2023 Agosto | 23 | 25 | 48 |
| 2023 Julio | 36 | 57 | 93 |
| 2023 Junio | 49 | 28 | 77 |
| 2023 Mayo | 45 | 36 | 81 |
| 2023 Abril | 46 | 24 | 70 |
| 2023 Marzo | 29 | 38 | 67 |
| 2023 Febrero | 33 | 28 | 61 |
| 2023 Enero | 30 | 34 | 64 |
| 2022 Diciembre | 38 | 42 | 80 |
| 2022 Noviembre | 13 | 27 | 40 |
| 2022 Octubre | 26 | 19 | 45 |
| 2022 Septiembre | 25 | 36 | 61 |
| 2022 Agosto | 21 | 42 | 63 |
| 2022 Julio | 15 | 38 | 53 |
| 2022 Junio | 15 | 21 | 36 |
| 2022 Mayo | 28 | 46 | 74 |
| 2022 Abril | 32 | 36 | 68 |
| 2022 Marzo | 43 | 68 | 111 |
| 2022 Febrero | 27 | 40 | 67 |
| 2022 Enero | 24 | 40 | 64 |
| 2021 Diciembre | 27 | 47 | 74 |
| 2021 Noviembre | 29 | 51 | 80 |
| 2021 Octubre | 32 | 52 | 84 |
| 2021 Septiembre | 25 | 48 | 73 |
| 2021 Agosto | 19 | 51 | 70 |
| 2021 Julio | 13 | 33 | 46 |
| 2021 Junio | 45 | 48 | 93 |
| 2021 Mayo | 29 | 38 | 67 |
| 2021 Abril | 80 | 31 | 111 |
| 2021 Marzo | 83 | 27 | 110 |
| 2021 Febrero | 56 | 33 | 89 |
| 2021 Enero | 25 | 17 | 42 |
| 2020 Diciembre | 39 | 16 | 55 |
| 2020 Noviembre | 24 | 19 | 43 |
| 2020 Octubre | 34 | 15 | 49 |
| 2020 Septiembre | 29 | 10 | 39 |
| 2020 Agosto | 27 | 31 | 58 |
| 2020 Julio | 23 | 23 | 46 |
| 2020 Junio | 29 | 25 | 54 |
| 2020 Mayo | 31 | 26 | 57 |
| 2020 Abril | 25 | 24 | 49 |
| 2020 Marzo | 29 | 31 | 60 |
| 2020 Febrero | 3 | 7 | 10 |
| 2020 Enero | 0 | 17 | 17 |
| 2019 Diciembre | 0 | 13 | 13 |
| 2019 Noviembre | 0 | 1 | 1 |
| 2019 Octubre | 0 | 5 | 5 |
| 2019 Septiembre | 0 | 17 | 17 |
| 2019 Agosto | 0 | 6 | 6 |
| 2019 Julio | 0 | 11 | 11 |
| 2019 Junio | 0 | 7 | 7 |
| 2019 Mayo | 0 | 51 | 51 |
| 2019 Abril | 0 | 25 | 25 |
| 2019 Marzo | 1 | 6 | 7 |
| 2019 Febrero | 1 | 7 | 8 |
| 2019 Enero | 1 | 1 | 2 |
| 2018 Diciembre | 1 | 4 | 5 |
| 2018 Noviembre | 11 | 7 | 18 |
| 2018 Octubre | 9 | 0 | 9 |
| 2018 Septiembre | 1 | 0 | 1 |
| 2018 Mayo | 0 | 1 | 1 |
| 2018 Abril | 0 | 2 | 2 |
| 2018 Marzo | 3 | 2 | 5 |
| 2018 Febrero | 17 | 12 | 29 |
| 2018 Enero | 18 | 12 | 30 |
| 2017 Diciembre | 25 | 9 | 34 |
| 2017 Noviembre | 22 | 4 | 26 |
| 2017 Octubre | 25 | 5 | 30 |
| 2017 Septiembre | 25 | 13 | 38 |
| 2017 Agosto | 23 | 15 | 38 |
| 2017 Julio | 19 | 9 | 28 |
| 2017 Junio | 34 | 14 | 48 |
| 2017 Mayo | 23 | 11 | 34 |
| 2017 Abril | 34 | 4 | 38 |
| 2017 Marzo | 27 | 24 | 51 |
| 2017 Febrero | 24 | 10 | 34 |
| 2017 Enero | 29 | 5 | 34 |
| 2016 Diciembre | 52 | 12 | 64 |
| 2016 Noviembre | 40 | 6 | 46 |
| 2016 Octubre | 32 | 20 | 52 |
| 2016 Septiembre | 43 | 9 | 52 |
| 2016 Agosto | 64 | 7 | 71 |
| 2016 Julio | 38 | 8 | 46 |
| 2016 Junio | 12 | 7 | 19 |
| 2016 Mayo | 7 | 5 | 12 |
| 2016 Abril | 5 | 25 | 30 |
| 2016 Marzo | 18 | 1 | 19 |
| 2016 Febrero | 14 | 9 | 23 |
| 2016 Enero | 13 | 11 | 24 |
| 2015 Diciembre | 17 | 2 | 19 |
| 2015 Noviembre | 17 | 11 | 28 |
| 2015 Octubre | 7 | 9 | 16 |
| 2015 Septiembre | 9 | 7 | 16 |
| 2015 Agosto | 14 | 1 | 15 |
| 2015 Julio | 49 | 7 | 56 |
| 2015 Junio | 34 | 8 | 42 |
| 2015 Mayo | 89 | 13 | 102 |
| 2015 Abril | 55 | 21 | 76 |
| 2015 Marzo | 47 | 24 | 71 |
| 2015 Febrero | 36 | 18 | 54 |
| 2015 Enero | 38 | 16 | 54 |
| 2014 Diciembre | 37 | 10 | 47 |
| 2014 Noviembre | 16 | 11 | 27 |
| 2014 Octubre | 38 | 18 | 56 |
| 2014 Septiembre | 26 | 17 | 43 |
| 2014 Agosto | 41 | 12 | 53 |
| 2014 Julio | 51 | 17 | 68 |
| 2014 Junio | 40 | 13 | 53 |
| 2014 Mayo | 50 | 19 | 69 |
| 2014 Abril | 59 | 14 | 73 |
| 2014 Marzo | 55 | 26 | 81 |
| 2014 Febrero | 47 | 13 | 60 |
| 2014 Enero | 51 | 19 | 70 |
| 2013 Diciembre | 36 | 18 | 54 |
| 2013 Noviembre | 31 | 27 | 58 |
| 2013 Octubre | 33 | 28 | 61 |
| 2013 Septiembre | 32 | 20 | 52 |
| 2013 Agosto | 18 | 25 | 43 |
| 2013 Julio | 30 | 30 | 60 |
| 2013 Junio | 22 | 20 | 42 |
| 2013 Mayo | 18 | 22 | 40 |
| 2013 Abril | 22 | 33 | 55 |
| 2013 Marzo | 27 | 41 | 68 |
| 2013 Febrero | 17 | 18 | 35 |
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