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Case report
Nelson Syndrome: A Rare Cause of Generalized Hyperpigmentation of the Skin
Aspectos prácticos de la quinacrina como tratamiento del lupus eritematoso cutáneo: serie de casos
R. Barabash
Autor para correspondencia
romanbarabash@hotmail.com

Corresponding author.
, F.G. Moreno-Suárez, L. Rodríguez, A.M. Molina, J. Conejo-Mir
Servicio de Dermatología, Hospitales Universitarios Virgen del Rocío, Sevilla, Spain
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    "titulo" => "Nelson Syndrome&#58; A Rare Cause of Generalized Hyperpigmentation of the Skin"
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      "es" => array:1 [
        "titulo" => "Aspectos pr&#225;cticos de la quinacrina como tratamiento del lupus eritematoso cut&#225;neo&#58; serie de casos"
      ]
    ]
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    "fechaRecibido" => "2009-02-03"
    "fechaAceptado" => "2009-04-30"
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            1 => "Hyperpigmentation"
            2 => "Adrenalectomy"
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            0 => "S&#237;ndrome de Nelson"
            1 => "Hiperpigmentaci&#243;n"
            2 => "Suprarrenalectom&#237;a"
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        ]
      ]
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    "resumen" => array:2 [
      "en" => array:2 [
        "titulo" => "Abstract"
        "resumen" => "<p class="elsevierStyleSimplePara elsevierViewall">Nelson syndrome is a rare cause of generalized mucocutaneous hyperpigmentation&#46; Its clinical manifestations are due to excessive secretion of adrenocorticotropic hormone from a pituitary adenoma&#44; which develops after bilateral therapeutic adrenalectomy&#46; As this operation has fallen into disuse&#44; Nelson syndrome is now extremely rare and difficult to recognize&#46; We present a very severe case of generalized hyperpigmentation due to Nelson syndrome in a 37-year-old woman&#46;</p>"
      ]
      "es" => array:2 [
        "titulo" => "Resumen"
        "resumen" => "<p class="elsevierStyleSimplePara elsevierViewall">El s&#237;ndrome de Nelson &#40;SN&#41; supone una causa infrecuente de hiperpigmentaci&#243;n mucocut&#225;nea generalizada&#44; cuyas manifestaciones cl&#237;nicas se derivan de la secreci&#243;n excesiva de corticotropina por un adenoma hipofisario secundario a la realizaci&#243;n de una suprarrenalectom&#237;a bilateral terap&#233;utica&#46; Debido a que esta intervenci&#243;n quir&#250;rgica ha ca&#237;do en desuso en la actualidad&#44; su presentaci&#243;n es hoy sumamente rara y poco reconocible&#46; Presentamos un caso muy grave de hiperpigmentaci&#243;n generalizada por SN en una paciente de 37 a&#241;os&#46;</p>"
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