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        "titulo" => "Abstract"
        "resumen" => "<span class="elsevierStyleSectionTitle">Background</span><p class="elsevierStyleSimplePara elsevierViewall">Surgical treatment of skin melanoma with skin margins in accordance with tumor thickness often necessitates covering the surgical defect with full or partial thickness skin grafts&#46; When selective sentinel node biopsy is indicated&#44; traditional procedures require 3 incisions&#58; 1 in the region of the primary tumor covered by the graft&#44; 1 in the axilla or groin corresponding to the site of the selective sentinel lymphnode biopsy&#44; and 1&#8212;almost always the most uncomfortable&#8212;in the donor site for the skin graft&#46;</p> <span class="elsevierStyleSectionTitle">Patients and methods</span><p class="elsevierStyleSimplePara elsevierViewall">We present 10 patients attended in our department who underwent an alternative technique to reduce the number of wounds&#46; A full thickness skin graft was obtained from the axillary or inguinal region covering the sentinel node&#46;</p> <span class="elsevierStyleSectionTitle">Results</span><p class="elsevierStyleSimplePara elsevierViewall">Sentinel node biopsy was positive in 1 patient&#44; who subsequently underwent inguinal lymphadenectomy&#46; Only 1 mild postoperative complication was reported in a patient with partial graft loss&#46; The mean hospital stay was 6&#46;2 days&#46; After follow-up ranging from 11 to 56 months&#44; no local recurrences or metastases had been detected&#46;</p> <span class="elsevierStyleSectionTitle">Conclusion</span><p class="elsevierStyleSimplePara elsevierViewall">The technique we present has the advantage of further simplifying surgical treatment for melanoma&#46; It reduces the problems associated with sentinel node dissection by affording a wider access and is also associated with less morbidity&#46;</p>"
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        "resumen" => "<span class="elsevierStyleSectionTitle">Introducci&#243;n</span><p class="elsevierStyleSimplePara elsevierViewall">El tratamiento quir&#250;rgico del melanoma cut&#225;neo con unos m&#225;rgenes adecuados al espesor del tumor va a hacer que&#44; en ciertas localizaciones&#44; sea frecuente tener que cubrir el defecto quir&#250;rgico mediante injertos de piel total o parcial&#46; Cuando haya que realizar biopsia selectiva del ganglio centinela &#40;BSGC&#41; con la t&#233;cnica cl&#225;sica el paciente tendr&#225; tres heridas&#44; una en la zona del primario cubierta por el injerto&#44; otra en la axila o la ingle&#44; por donde hemos hecho la BSGC&#44; y otra&#44; casi siempre la m&#225;s molesta&#44; en la zona dadora del injerto&#46;</p> <span class="elsevierStyleSectionTitle">Material y m&#233;todos</span><p class="elsevierStyleSimplePara elsevierViewall">Presentamos 10 pacientes tratados en nuestro Servicio en los que se realiz&#243; una t&#233;cnica alternativa que redujo el n&#250;mero resultante de heridas&#46; Para ello se obtuvo el injerto de piel total de la zona de la axila o de la ingle que recubr&#237;a el ganglio centinela&#46;</p> <span class="elsevierStyleSectionTitle">Resultados</span><p class="elsevierStyleSimplePara elsevierViewall">La BSGC s&#243;lo fue positiva en un caso&#44; al que se realiz&#243; linfadenectom&#237;a inguinal&#46; S&#243;lo se produjo una complicaci&#243;n postoperatoria leve en un paciente&#44; con una p&#233;rdida parcial del injerto y la estancia hospitalaria media fue de 6&#44;2 d&#237;as&#46; Despu&#233;s de un seguimiento variable entre 11 y 56 meses&#44; no se han detectado casos de recidiva local ni de met&#225;stasis&#46;</p> <span class="elsevierStyleSectionTitle">Conclusiones</span><p class="elsevierStyleSimplePara elsevierViewall">La t&#233;cnica que presentamos tiene la ventaja de que simplifica a&#250;n m&#225;s el tratamiento quir&#250;rgico del melanoma&#44; reduce las dificultades en la disecci&#243;n del ganglio centinela al permitirnos una v&#237;a de abordaje m&#225;s amplia y&#44; adem&#225;s&#44; disminuye la morbilidad asociada a la intervenci&#243;n&#46;</p>"
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                      "titulo" => "Sentinel lymph node biopsy used as full-thickness skin graft donor for cutaneous melanoma"
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                          "autores" => array:3 [
                            0 => "A&#46; Dresler"
                            1 => "J&#46;A&#46; Kuhn"
                            2 => "T&#46;M&#46; McCarty"
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                    ]
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                        "tituloSerie" => "Am J Surg"
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                        "paginaFinal" => "178"
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                      "titulo" => "Pr&#233;l&#232;vement de greffe de peau totale en regard du ganglion sentinelle&#58; un site donneur preferential apr&#232;s ex&#233;r&#232;se de m&#233;lanomes cutan&#233;s&#46; &#193; propos de 16 cas"
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                            2 => "L&#46; Lantieri"
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                    ]
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                        "tituloSerie" => "Ann Chir Plast Esthet"
                        "fecha" => "2007"
                        "volumen" => "52"
                        "paginaInicial" => "35"
                        "paginaFinal" => "38"
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                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16857304"
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                            2 => "D&#46; Yu"
                            3 => "D&#46; Pel&#225;ez"
                            4 => "A&#46;I&#46; Riker"
                            5 => "S&#46; Dessureault"
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                        "tituloSerie" => "Ann Surg Oncol"
                        "fecha" => "2008"
                        "volumen" => "15"
                        "paginaInicial" => "1733"
                        "paginaFinal" => "1740"
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                            3 => "E&#46; D&#237;az Rubio"
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                        "tituloSerie" => "Arch Surg"
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                        "paginaFinal" => "441"
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                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/2009058"
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                            5 => "A&#46; Barchuk"
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                        "tituloSerie" => "N Engl J Med"
                        "fecha" => "1988"
                        "volumen" => "318"
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                        "paginaFinal" => "1162"
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                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/3079582"
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                            3 => "M&#46;I&#46; Ross"
                            4 => "M&#46;M&#46; Urist"
                            5 => "C&#46;P&#46; Karakousis"
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                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Long term results of a randomized study by the Swedish Melanoma Study Group on 2-cm versus 5-cm resection margins for patients with cutaneous melanoma with a tumor thickness of 0&#46;8-2&#46;0 mm"
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                            5 => "H&#46; Johansson"
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                        "paginaFinal" => "1501"
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            ]
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                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Efficacy of 2-cm surgical margins for intermediate-thickness melanomas &#40;1 to 4 mm&#41;&#46; Results of a multi-institutional randomized surgical trial"
                      "autores" => array:1 [
                        0 => array:2 [
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                            5 => "K&#46; Drzewiecki"
                          ]
                        ]
                      ]
                    ]
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                      "Revista" => array:7 [
                        "tituloSerie" => "Ann Surg"
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                        "paginaInicial" => "262"
                        "paginaFinal" => "267"
                        "link" => array:1 [
                          0 => array:2 [
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                            "web" => "Medline"
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                    0 => array:2 [
                      "titulo" => "Excision margins in highrisk malignant melanoma"
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                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "J&#46;M&#46; Thomas"
                            1 => "J&#46; Newton-Bishop"
                            2 => "R&#46; A&#8217;Hern"
                            3 => "G&#46; Coombes"
                            4 => "M&#46; Timmons"
                            5 => "J&#46; Evans"
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                      ]
                    ]
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                      "doi" => "10.1056/NEJMoa030681"
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                        "tituloSerie" => "N Engl J Med"
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                        "paginaFinal" => "766"
                        "link" => array:1 [
                          0 => array:2 [
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                      "titulo" => "Surgical margins and prognostic factors in patients with thick &#40;&#62;4 mm&#41; primary melanoma"
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                            2 => "J&#46;E&#46; Gershenwald"
                            3 => "J&#46;E&#46; Lee"
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                            5 => "P&#46;F&#46; Mansfield"
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                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Ann Surg Oncol"
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                        "paginaInicial" => "322"
                        "paginaFinal" => "328"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9641453"
                            "web" => "Medline"
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                      ]
                    ]
                  ]
                ]
              ]
            ]
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                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Excision of underlying fascia with a primary malignant melanoma&#58; effect on recurrence and survival rates"
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                          "etal" => false
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                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Surgery"
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                        "paginaInicial" => "615"
                        "paginaFinal" => "618"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/7123480"
                            "web" => "Medline"
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                    ]
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              ]
            ]
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                    0 => array:2 [
                      "titulo" => "Skin grafting&#46; From here to there"
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                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "D&#46; Ratner"
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                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Dermatol Clin"
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                        "volumen" => "16"
                        "paginaInicial" => "75"
                        "paginaFinal" => "90"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9460579"
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Original articles
Full Thickness Skin Grafts Obtained From the Skin Overlying Sentinel Nodes
Injertos de Piel Total Obtenidos de la Zona del Ganglio Centinela
A. Clemente-Ruiz de Almiróna,
Autor para correspondencia
acra@meditex.es

Correspondence: Servicio de Dermatología, Hospital Universitario San Cecilio, Avda. Dr. Olóriz, 16, 18012 Granada, Spain.
, S. Serrano-Ortegab
a Servicio de Dermatología, Hospital Universitario San Cecilio, Granada, España
b Facultad de Medicina, Universidad de Granada, Granada, Spain
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        "resumen" => "<span class="elsevierStyleSectionTitle">Introducci&#243;n</span><p class="elsevierStyleSimplePara elsevierViewall">El tratamiento quir&#250;rgico del melanoma cut&#225;neo con unos m&#225;rgenes adecuados al espesor del tumor va a hacer que&#44; en ciertas localizaciones&#44; sea frecuente tener que cubrir el defecto quir&#250;rgico mediante injertos de piel total o parcial&#46; Cuando haya que realizar biopsia selectiva del ganglio centinela &#40;BSGC&#41; con la t&#233;cnica cl&#225;sica el paciente tendr&#225; tres heridas&#44; una en la zona del primario cubierta por el injerto&#44; otra en la axila o la ingle&#44; por donde hemos hecho la BSGC&#44; y otra&#44; casi siempre la m&#225;s molesta&#44; en la zona dadora del injerto&#46;</p> <span class="elsevierStyleSectionTitle">Material y m&#233;todos</span><p class="elsevierStyleSimplePara elsevierViewall">Presentamos 10 pacientes tratados en nuestro Servicio en los que se realiz&#243; una t&#233;cnica alternativa que redujo el n&#250;mero resultante de heridas&#46; Para ello se obtuvo el injerto de piel total de la zona de la axila o de la ingle que recubr&#237;a el ganglio centinela&#46;</p> <span class="elsevierStyleSectionTitle">Resultados</span><p class="elsevierStyleSimplePara elsevierViewall">La BSGC s&#243;lo fue positiva en un caso&#44; al que se realiz&#243; linfadenectom&#237;a inguinal&#46; S&#243;lo se produjo una complicaci&#243;n postoperatoria leve en un paciente&#44; con una p&#233;rdida parcial del injerto y la estancia hospitalaria media fue de 6&#44;2 d&#237;as&#46; Despu&#233;s de un seguimiento variable entre 11 y 56 meses&#44; no se han detectado casos de recidiva local ni de met&#225;stasis&#46;</p> <span class="elsevierStyleSectionTitle">Conclusiones</span><p class="elsevierStyleSimplePara elsevierViewall">La t&#233;cnica que presentamos tiene la ventaja de que simplifica a&#250;n m&#225;s el tratamiento quir&#250;rgico del melanoma&#44; reduce las dificultades en la disecci&#243;n del ganglio centinela al permitirnos una v&#237;a de abordaje m&#225;s amplia y&#44; adem&#225;s&#44; disminuye la morbilidad asociada a la intervenci&#243;n&#46;</p>"
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      "titulo" => "References"
      "seccion" => array:1 [
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              "identificador" => "bib1"
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                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Sentinel lymph node biopsy used as full-thickness skin graft donor for cutaneous melanoma"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "A&#46; Dresler"
                            1 => "J&#46;A&#46; Kuhn"
                            2 => "T&#46;M&#46; McCarty"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Am J Surg"
                        "fecha" => "2002"
                        "volumen" => "184"
                        "paginaInicial" => "176"
                        "paginaFinal" => "178"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12169366"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
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            1 => array:3 [
              "identificador" => "bib2"
              "etiqueta" => "2&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Pr&#233;l&#232;vement de greffe de peau totale en regard du ganglion sentinelle&#58; un site donneur preferential apr&#232;s ex&#233;r&#232;se de m&#233;lanomes cutan&#233;s&#46; &#193; propos de 16 cas"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "M&#46; Chennoufi"
                            1 => "T&#46; Guihard"
                            2 => "L&#46; Lantieri"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1016/j.anplas.2006.06.003"
                      "Revista" => array:6 [
                        "tituloSerie" => "Ann Chir Plast Esthet"
                        "fecha" => "2007"
                        "volumen" => "52"
                        "paginaInicial" => "35"
                        "paginaFinal" => "38"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16857304"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            2 => array:3 [
              "identificador" => "bib3"
              "etiqueta" => "3&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Full-thickness grafts procured from skin overlying the sentinel node basin&#59; reconstruction of primary cutaneous malignancy excision defects"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "J&#46;M&#46; Lewis"
                            1 => "J&#46;S&#46; Zager"
                            2 => "D&#46; Yu"
                            3 => "D&#46; Pel&#225;ez"
                            4 => "A&#46;I&#46; Riker"
                            5 => "S&#46; Dessureault"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1245/s10434-008-9887-0"
                      "Revista" => array:7 [
                        "tituloSerie" => "Ann Surg Oncol"
                        "fecha" => "2008"
                        "volumen" => "15"
                        "paginaInicial" => "1733"
                        "paginaFinal" => "1740"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/18379848"
                            "web" => "Medline"
                          ]
                        ]
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              ]
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            3 => array:3 [
              "identificador" => "bib4"
              "etiqueta" => "4&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Panor&#225;mica actual del melanoma"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "F&#46; &#193;lvarez-Mon Soto"
                            1 => "F&#46; Camacho Mart&#237;nez"
                            2 => "J&#46;L&#46; D&#237;az P&#233;rez"
                            3 => "E&#46; D&#237;az Rubio"
                            4 => "J&#46;L&#46; Gonz&#225;lez Larriba"
                            5 => "V&#46; Guill&#233;n Porta"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Libro" => array:3 [
                        "fecha" => "1997"
                        "editorial" => "Acci&#243;n M&#233;dica"
                        "editorialLocalizacion" => "Madrid"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            4 => array:3 [
              "identificador" => "bib5"
              "etiqueta" => "5&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Narrow excision &#40;1 cm margin&#41;&#46; A safe procedure for thin cutaneous melanoma"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "U&#46; Veronesi"
                            1 => "N&#46; Cascinelli"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:7 [
                        "tituloSerie" => "Arch Surg"
                        "fecha" => "1991"
                        "volumen" => "126"
                        "paginaInicial" => "438"
                        "paginaFinal" => "441"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/2009058"
                            "web" => "Medline"
                          ]
                        ]
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            ]
            5 => array:3 [
              "identificador" => "bib6"
              "etiqueta" => "6&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Thin stage I primary cutaneous malignant melanoma&#46; Comparison of excision with margins of 1 or 3 cm"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "U&#46; Veronesi"
                            1 => "N&#46; Cascinelli"
                            2 => "J&#46; Adamus"
                            3 => "C&#46; Balch"
                            4 => "D&#46; Bandiera"
                            5 => "A&#46; Barchuk"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1056/NEJM198805053181804"
                      "Revista" => array:7 [
                        "tituloSerie" => "N Engl J Med"
                        "fecha" => "1988"
                        "volumen" => "318"
                        "paginaInicial" => "1159"
                        "paginaFinal" => "1162"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/3079582"
                            "web" => "Medline"
                          ]
                        ]
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                          "issn" => "14744422"
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                  ]
                ]
              ]
            ]
            6 => array:3 [
              "identificador" => "bib7"
              "etiqueta" => "7&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Long term results of a prospective surgical trial comparing 2 cm vs&#46; 4 cm excision margins for 740 patients with 1-4 mm melanomas"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "C&#46;M&#46; Balch"
                            1 => "S&#46;J&#46; Soong"
                            2 => "T&#46; Smith"
                            3 => "M&#46;I&#46; Ross"
                            4 => "M&#46;M&#46; Urist"
                            5 => "C&#46;P&#46; Karakousis"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Ann Surg Oncol"
                        "fecha" => "2001"
                        "volumen" => "8"
                        "paginaInicial" => "101"
                        "paginaFinal" => "108"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11258773"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            7 => array:3 [
              "identificador" => "bib8"
              "etiqueta" => "8&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Surgical margins in cutaneous melanoma &#40;2 cm versus 5 cm for lesions measuring less than 2&#46;1-mm thick&#41;"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "D&#46; Khayat"
                            1 => "O&#46; Rixe"
                            2 => "G&#46; Martin"
                            3 => "C&#46; Soubrane"
                            4 => "M&#46; Banzet"
                            5 => "J&#46;A&#46; Bazex"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1002/cncr.11272"
                      "Revista" => array:6 [
                        "tituloSerie" => "Cancer"
                        "fecha" => "2003"
                        "volumen" => "97"
                        "paginaInicial" => "1941"
                        "paginaFinal" => "1946"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12673721"
                            "web" => "Medline"
                          ]
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                      ]
                    ]
                  ]
                ]
              ]
            ]
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              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Long term results of a randomized study by the Swedish Melanoma Study Group on 2-cm versus 5-cm resection margins for patients with cutaneous melanoma with a tumor thickness of 0&#46;8-2&#46;0 mm"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "G&#46; Cohn-Cedermark"
                            1 => "L&#46;E&#46; Rutqvist"
                            2 => "R&#46; Andersson"
                            3 => "M&#46; Breivald"
                            4 => "C&#46; Ingvar"
                            5 => "H&#46; Johansson"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Cancer"
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                        "paginaInicial" => "1495"
                        "paginaFinal" => "1501"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11013363"
                            "web" => "Medline"
                          ]
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                      ]
                    ]
                  ]
                ]
              ]
            ]
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              "etiqueta" => "10&#46;"
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                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Efficacy of 2-cm surgical margins for intermediate-thickness melanomas &#40;1 to 4 mm&#41;&#46; Results of a multi-institutional randomized surgical trial"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "C&#46;M&#46; Balch"
                            1 => "M&#46;M&#46; Urist"
                            2 => "C&#46;P&#46; Karakousis"
                            3 => "T&#46;J&#46; Smith"
                            4 => "W&#46;J&#46; Temple"
                            5 => "K&#46; Drzewiecki"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:7 [
                        "tituloSerie" => "Ann Surg"
                        "fecha" => "1993"
                        "volumen" => "218"
                        "paginaInicial" => "262"
                        "paginaFinal" => "267"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8373269"
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                          ]
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            10 => array:3 [
              "identificador" => "bib11"
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                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Excision margins in highrisk malignant melanoma"
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                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "J&#46;M&#46; Thomas"
                            1 => "J&#46; Newton-Bishop"
                            2 => "R&#46; A&#8217;Hern"
                            3 => "G&#46; Coombes"
                            4 => "M&#46; Timmons"
                            5 => "J&#46; Evans"
                          ]
                        ]
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                    ]
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                    0 => array:2 [
                      "doi" => "10.1056/NEJMoa030681"
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                        "tituloSerie" => "N Engl J Med"
                        "fecha" => "2004"
                        "volumen" => "350"
                        "paginaInicial" => "757"
                        "paginaFinal" => "766"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/14973217"
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              "etiqueta" => "12&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Surgical margins and prognostic factors in patients with thick &#40;&#62;4 mm&#41; primary melanoma"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "K&#46;M&#46; Heaton"
                            1 => "J&#46;J&#46; Sussman"
                            2 => "J&#46;E&#46; Gershenwald"
                            3 => "J&#46;E&#46; Lee"
                            4 => "D&#46;S&#46; Reintgen"
                            5 => "P&#46;F&#46; Mansfield"
                          ]
                        ]
                      ]
                    ]
                  ]
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                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Ann Surg Oncol"
                        "fecha" => "1998"
                        "volumen" => "5"
                        "paginaInicial" => "322"
                        "paginaFinal" => "328"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9641453"
                            "web" => "Medline"
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                      ]
                    ]
                  ]
                ]
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            ]
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              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Excision of underlying fascia with a primary malignant melanoma&#58; effect on recurrence and survival rates"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "D&#46;E&#46; Kenady"
                            1 => "B&#46;W&#46; Brown"
                            2 => "C&#46;M&#46; McPride"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Surgery"
                        "fecha" => "1982"
                        "volumen" => "92"
                        "paginaInicial" => "615"
                        "paginaFinal" => "618"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/7123480"
                            "web" => "Medline"
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                    ]
                  ]
                ]
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              "identificador" => "bib14"
              "etiqueta" => "14&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Skin grafting&#46; From here to there"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "D&#46; Ratner"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Dermatol Clin"
                        "fecha" => "1998"
                        "volumen" => "16"
                        "paginaInicial" => "75"
                        "paginaFinal" => "90"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9460579"
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                      ]
                    ]
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                ]
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2021 Septiembre 23 40 63
2021 Agosto 25 24 49
2021 Julio 15 37 52
2021 Junio 16 30 46
2021 Mayo 14 22 36
2021 Abril 54 92 146
2021 Marzo 48 15 63
2021 Febrero 51 26 77
2021 Enero 19 14 33
2020 Diciembre 24 24 48
2020 Noviembre 15 15 30
2020 Octubre 21 9 30
2020 Septiembre 28 7 35
2020 Agosto 23 15 38
2020 Julio 17 6 23
2020 Junio 31 22 53
2020 Mayo 23 17 40
2020 Abril 13 12 25
2020 Marzo 15 18 33
2020 Febrero 0 3 3
2020 Enero 0 7 7
2019 Diciembre 0 5 5
2019 Noviembre 0 4 4
2019 Octubre 0 5 5
2019 Septiembre 0 2 2
2019 Agosto 0 2 2
2019 Julio 0 9 9
2019 Junio 0 5 5
2019 Mayo 0 74 74
2019 Abril 0 14 14
2019 Marzo 0 1 1
2019 Febrero 0 7 7
2018 Junio 0 4 4
2018 Mayo 0 3 3
2018 Abril 0 3 3
2018 Marzo 0 1 1
2018 Febrero 8 4 12
2018 Enero 21 8 29
2017 Diciembre 15 9 24
2017 Noviembre 10 2 12
2017 Octubre 14 4 18
2017 Septiembre 19 16 35
2017 Agosto 39 6 45
2017 Julio 34 3 37
2017 Junio 29 28 57
2017 Mayo 31 14 45
2017 Abril 36 29 65
2017 Marzo 35 33 68
2017 Febrero 12 12 24
2017 Enero 7 9 16
2016 Diciembre 27 5 32
2016 Noviembre 20 12 32
2016 Octubre 29 7 36
2016 Septiembre 28 6 34
2016 Agosto 25 7 32
2016 Julio 26 14 40
2016 Junio 13 8 21
2016 Mayo 6 9 15
2016 Abril 9 10 19
2016 Marzo 11 8 19
2016 Febrero 4 12 16
2016 Enero 10 8 18
2015 Diciembre 10 3 13
2015 Noviembre 18 6 24
2015 Octubre 5 3 8
2015 Septiembre 9 3 12
2015 Agosto 9 3 12
2015 Julio 32 6 38
2015 Junio 14 5 19
2015 Mayo 56 8 64
2015 Abril 25 6 31
2015 Marzo 30 6 36
2015 Febrero 25 13 38
2015 Enero 14 13 27
2014 Diciembre 27 10 37
2014 Noviembre 15 12 27
2014 Octubre 22 13 35
2014 Septiembre 27 9 36
2014 Agosto 39 15 54
2014 Julio 31 18 49
2014 Junio 35 9 44
2014 Mayo 48 12 60
2014 Abril 30 8 38
2014 Marzo 45 20 65
2014 Febrero 28 14 42
2014 Enero 30 14 44
2013 Diciembre 36 14 50
2013 Noviembre 26 18 44
2013 Octubre 24 21 45
2013 Septiembre 28 19 47
2013 Agosto 23 29 52
2013 Julio 40 33 73
2013 Junio 22 31 53
2013 Mayo 25 32 57
2013 Abril 30 24 54
2013 Marzo 39 20 59
2013 Febrero 29 12 41
2013 Enero 7 3 10
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