Correspondence: Servicio de Dermatología Hospital de la Santa Creu i de Sant Pau, Sant Antoni Maria Claret, 167, 08025 Barcelona, Spain.
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The role of systemic treatment in the management of psoriasis is being reviewed on the basis of a large volume of scientific evidence on the efficacy and safety of biologic agents, and new therapeutic goals and strategies are being devised for patients with moderate to severe psoriasis. This has led to the need to establish severity criteria that will provide the rationale for the indication of the different systemic agents currently available for the treatment of moderate to severe psoriasis, as well as therapeutic goals, efficacy measures, therapeutic strategies, screening protocols, and choice of treatment based on the risk-benefit ratio of the different agents. These criteria must be established through consensus by experienced dermatologists and based on available scientific evidence. The present document reflects the consensus of the Spanish Psoriasis Group on these different issues in the management of moderate to severe psoriasis.</p>" ] "es" => array:2 [ "titulo" => "Resumen" "resumen" => "<p class="elsevierStyleSimplePara elsevierViewall">El tratamiento de la psoriasis se ha visto revolucionado por la introducción de los agentes biológicos, que permiten obtener blanqueamientos y mejorías a largo plazo sin el riesgo de toxicidad que ha venido limitando el tratamiento de estos pacientes con agentes sistémicos clásicos. Se ha acumulado abundante evidencia científica con respecto a la eficacia y seguridad de los agentes biológicos, que ha llevado a revisar el papel del tratamiento sistémico en general y ha permitido establecer nuevos objetivos y estrategias terapéuticas en los pacientes con psoriasis moderada a grave. En este contexto nuevo se hace necesario establecer, de forma consensuada por especialistas expertos y basada en la evidencia científica disponible, criterios de gravedad que justifiquen la indicación de los diferentes tratamientos sistémicos actualmente disponibles para la psoriasis, así como objetivos terapéuticos y parámetros de eficacia, estrategias de tratamiento, cribaje de los pacientes y selección del tratamiento basada en criterios de beneficio/riesgo. El presente documento recoge el consenso del Grupo Español de Psoriasis en estos diferentes aspectos del manejo de la psoriasis moderada a grave.</p>" ] ] "NotaPie" => array:1 [ 0 => array:2 [ "etiqueta" => "☆" "nota" => "<p class="elsevierStyleNotepara">The Spanish Psoriasis Group is a working group of the Spanish Academy of Dermatology and Venereology. The 50 members of the group are dermatologists working in hospital settings who have special expertise in the treatment of patients with psoriasis and are involved in clinical and therapeutic research in this specialized area.</p>" ] ] "bibliografia" => array:2 [ "titulo" => "References" "seccion" => array:1 [ 0 => array:1 [ "bibliografiaReferencia" => array:34 [ 0 => array:3 [ "identificador" => "bib1" "etiqueta" => "1." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Prevalence of psoriasis in Spain (Epiderma Project: phase I)" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "C. Ferrándiz" 1 => "X. Bordas" 2 => "V. García-Patos" 3 => "S. Puig" 4 => "R. Pujol" 5 => "A. 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año/Mes | Html | Total | |
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2024 Noviembre | 3 | 5 | 8 |
2024 Octubre | 75 | 61 | 136 |
2024 Septiembre | 54 | 32 | 86 |
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2023 Diciembre | 37 | 41 | 78 |
2023 Noviembre | 43 | 38 | 81 |
2023 Octubre | 31 | 27 | 58 |
2023 Septiembre | 28 | 26 | 54 |
2023 Agosto | 22 | 19 | 41 |
2023 Julio | 36 | 34 | 70 |
2023 Junio | 35 | 39 | 74 |
2023 Mayo | 57 | 42 | 99 |
2023 Abril | 27 | 31 | 58 |
2023 Marzo | 65 | 41 | 106 |
2023 Febrero | 19 | 23 | 42 |
2023 Enero | 35 | 27 | 62 |
2022 Diciembre | 31 | 53 | 84 |
2022 Noviembre | 14 | 41 | 55 |
2022 Octubre | 11 | 18 | 29 |
2022 Septiembre | 13 | 41 | 54 |
2022 Agosto | 13 | 40 | 53 |
2022 Julio | 19 | 30 | 49 |
2022 Junio | 15 | 39 | 54 |
2022 Mayo | 25 | 48 | 73 |
2022 Abril | 33 | 45 | 78 |
2022 Marzo | 37 | 51 | 88 |
2022 Febrero | 27 | 33 | 60 |
2022 Enero | 24 | 45 | 69 |
2021 Diciembre | 27 | 58 | 85 |
2021 Noviembre | 27 | 62 | 89 |
2021 Octubre | 21 | 54 | 75 |
2021 Septiembre | 31 | 50 | 81 |
2021 Agosto | 17 | 28 | 45 |
2021 Julio | 20 | 42 | 62 |
2021 Junio | 18 | 35 | 53 |
2021 Mayo | 19 | 44 | 63 |
2021 Abril | 74 | 56 | 130 |
2021 Marzo | 70 | 45 | 115 |
2021 Febrero | 37 | 25 | 62 |
2021 Enero | 29 | 20 | 49 |
2020 Diciembre | 27 | 20 | 47 |
2020 Noviembre | 18 | 22 | 40 |
2020 Octubre | 19 | 23 | 42 |
2020 Septiembre | 11 | 19 | 30 |
2020 Agosto | 31 | 30 | 61 |
2020 Julio | 26 | 20 | 46 |
2020 Junio | 22 | 26 | 48 |
2020 Mayo | 26 | 25 | 51 |
2020 Abril | 19 | 22 | 41 |
2020 Marzo | 24 | 20 | 44 |
2020 Febrero | 0 | 6 | 6 |
2020 Enero | 0 | 3 | 3 |
2019 Diciembre | 0 | 7 | 7 |
2019 Noviembre | 0 | 7 | 7 |
2019 Septiembre | 0 | 1 | 1 |
2019 Agosto | 0 | 3 | 3 |
2019 Julio | 0 | 1 | 1 |
2019 Junio | 0 | 12 | 12 |
2019 Mayo | 0 | 58 | 58 |
2019 Abril | 0 | 8 | 8 |
2019 Marzo | 0 | 16 | 16 |
2019 Febrero | 0 | 8 | 8 |
2018 Noviembre | 0 | 5 | 5 |
2018 Septiembre | 0 | 3 | 3 |
2018 Agosto | 0 | 5 | 5 |
2018 Julio | 0 | 4 | 4 |
2018 Junio | 0 | 7 | 7 |
2018 Mayo | 0 | 7 | 7 |
2018 Abril | 0 | 4 | 4 |
2018 Marzo | 0 | 6 | 6 |
2018 Febrero | 9 | 10 | 19 |
2018 Enero | 17 | 12 | 29 |
2017 Diciembre | 20 | 22 | 42 |
2017 Noviembre | 10 | 18 | 28 |
2017 Octubre | 12 | 30 | 42 |
2017 Septiembre | 13 | 24 | 37 |
2017 Agosto | 14 | 25 | 39 |
2017 Julio | 13 | 19 | 32 |
2017 Junio | 25 | 20 | 45 |
2017 Mayo | 28 | 37 | 65 |
2017 Abril | 22 | 17 | 39 |
2017 Marzo | 24 | 46 | 70 |
2017 Febrero | 18 | 21 | 39 |
2017 Enero | 8 | 19 | 27 |
2016 Diciembre | 28 | 18 | 46 |
2016 Noviembre | 26 | 33 | 59 |
2016 Octubre | 24 | 35 | 59 |
2016 Septiembre | 33 | 28 | 61 |
2016 Agosto | 33 | 18 | 51 |
2016 Julio | 30 | 12 | 42 |
2016 Junio | 7 | 15 | 22 |
2016 Mayo | 6 | 17 | 23 |
2016 Abril | 6 | 1 | 7 |
2016 Marzo | 4 | 5 | 9 |
2016 Febrero | 6 | 2 | 8 |
2016 Enero | 12 | 4 | 16 |
2015 Diciembre | 6 | 2 | 8 |
2015 Noviembre | 11 | 6 | 17 |
2015 Octubre | 4 | 8 | 12 |
2015 Septiembre | 6 | 8 | 14 |
2015 Agosto | 12 | 2 | 14 |
2015 Julio | 27 | 1 | 28 |
2015 Junio | 36 | 16 | 52 |
2015 Mayo | 73 | 25 | 98 |
2015 Abril | 30 | 41 | 71 |
2015 Marzo | 33 | 29 | 62 |
2015 Febrero | 22 | 24 | 46 |
2015 Enero | 25 | 23 | 48 |
2014 Diciembre | 29 | 30 | 59 |
2014 Noviembre | 17 | 16 | 33 |
2014 Octubre | 38 | 22 | 60 |
2014 Septiembre | 29 | 15 | 44 |
2014 Agosto | 34 | 17 | 51 |
2014 Julio | 37 | 23 | 60 |
2014 Junio | 45 | 15 | 60 |
2014 Mayo | 44 | 16 | 60 |
2014 Abril | 47 | 12 | 59 |
2014 Marzo | 60 | 21 | 81 |
2014 Febrero | 42 | 23 | 65 |
2014 Enero | 42 | 24 | 66 |
2013 Diciembre | 45 | 30 | 75 |
2013 Noviembre | 31 | 36 | 67 |
2013 Octubre | 26 | 47 | 73 |
2013 Septiembre | 32 | 34 | 66 |
2013 Agosto | 23 | 44 | 67 |
2013 Julio | 39 | 33 | 72 |
2013 Junio | 30 | 38 | 68 |
2013 Mayo | 19 | 33 | 52 |
2013 Abril | 22 | 46 | 68 |
2013 Marzo | 37 | 28 | 65 |
2013 Febrero | 36 | 8 | 44 |
2013 Enero | 10 | 5 | 15 |