Cutaneous Drug Reactions in HIV-Infected Patients in the HAART Era

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Alcalde Jaume Botella Mayor, 7, 03570 Villajoyosa, Alicante, Spain." ] ] ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Reacciones Cutáneas Adversas a Fármacos en los Pacientes con Infección por el VIH en la Era TARGA" ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaAceptado" => "2008-07-24" "PalabrasClave" => array:2 [ "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Key words" "identificador" => "xpalclavsec84458" "palabras" => array:5 [ 0 => "TARGA" 1 => "VIH" 2 => "HAART" 3 => "HIV" 4 => "cutaneous drug reactions" ] ] ] "es" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palabras clave" "identificador" => "xpalclavsec84457" "palabras" => array:3 [ 0 => "TARGA" 1 => "VIH" 2 => "efectos cutáneos adversos" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "en" => array:2 [ "titulo" => "Abstract" "resumen" => "The introduction of highly active antiretroviral treatment (HAART) in 1996 radically changed the clinical course of human immunodeficiency virus (HIV) infection as it led to a dramatic reduction in mortality in these patients. However, these treatments have their limitations, including adverse effects, therapeutic failure, pharmacokinetic interactions, the development of resistance, and abnormal immune responses. In this article we review the current situation of cutaneous drug reactions in HIV-infected patients." ] "es" => array:2 [ "titulo" => "Resumen" "resumen" => "La introducción del tratamiento antirretroviral de gran actividad (TARGA) en 1996 supuso un cambio radical en la historia natural de la infección por el virus de la inmunodeficiencia humana (VIH) al lograr reducir drásticamente la mortalidad en estos pacientes. No obstante, estos tratamientos no están exentos de limitaciones que incluyen efectos adversos, fracaso del tratamiento, interacciones farmacocinéticas, aparición de resistencias y respuestas inmunes anómalas. En este artículo se revisa la situación actual de las reacciones cutáneas adversas a fármacos en los pacientes con infección por el VIH." ] ] "bibliografia" => array:2 [ "titulo" => "References" "seccion" => array:1 [ 0 => array:1 [ "bibliografiaReferencia" => array:122 [ 0 => array:3 [ "identificador" => "bib1" "etiqueta" => "1." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Impact of protease inhibitors on AIDS-defining events and hospitalizations in 10 French AIDS reference centres. Fédération National des Centres de Lutte contre le SIDA" "autores" => array:1 [ 0 => array:2 [ …2] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "AIDS" "fecha" => "1997" "volumen" => "11" "paginaInicial" => "101" "paginaFinal" => "105" "link" => array:1 [ …1] ] ] ] ] ] ] 1 => array:3 [ "identificador" => "bib2" "etiqueta" => "2." 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Review

Cutaneous Drug Reactions in HIV-Infected Patients in the HAART Era

Reacciones Cutáneas Adversas a Fármacos en los Pacientes con Infección por el VIH en la Era TARGA

M. Blanesa,

Autor para correspondencia

blanes_marmar@gva.es

Correspondence: Unidad de Dermatología, Hospital Marina Baixa, Av. Alcalde Jaume Botella Mayor, 7, 03570 Villajoyosa, Alicante, Spain.

, I. Belinchónb, J. Portillac

a Unidad de Dermatología, Hospital Marina Baixa, Villajoyosa, Alicante, Spain

b Sección de Dermatología, Hospital General Universitario de Alicante, Spain

c Unidad de Enfermedades Infecciosas, Hospital General Universitario de Alicante, Spain

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Información del artículo

ISSN: 15782190
Idioma original: Inglés

DOI:10.1016/S1578-2190(09)70062-9

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