array:23 [
  "pii" => "S1578219009700496"
  "issn" => "15782190"
  "doi" => "10.1016/S1578-2190(09)70049-6"
  "estado" => "S300"
  "fechaPublicacion" => "2009-04-01"
  "aid" => "70049"
  "copyright" => "Academia Española de Dermatología y Venereología and Elsevier España, S.L."
  "copyrightAnyo" => "2009"
  "documento" => "article"
  "crossmark" => 0
  "subdocumento" => "sco"
  "cita" => "Actas Dermosifiliogr. 2009;100:227-30"
  "abierto" => array:3 [
    "ES" => true
    "ES2" => true
    "LATM" => true
  ]
  "gratuito" => true
  "lecturas" => array:2 [
    "total" => 2346
    "formatos" => array:3 [
      "EPUB" => 35
      "HTML" => 1556
      "PDF" => 755
    ]
  ]
  "itemSiguiente" => array:18 [
    "pii" => "S1578219009700502"
    "issn" => "15782190"
    "doi" => "10.1016/S1578-2190(09)70050-2"
    "estado" => "S300"
    "fechaPublicacion" => "2009-04-01"
    "aid" => "70050"
    "copyright" => "Academia Española de Dermatología y Venereología and Elsevier España, S.L."
    "documento" => "article"
    "crossmark" => 0
    "subdocumento" => "sco"
    "cita" => "Actas Dermosifiliogr. 2009;100:231-2"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:2 [
      "total" => 2307
      "formatos" => array:3 [
        "EPUB" => 38
        "HTML" => 1299
        "PDF" => 970
      ]
    ]
    "en" => array:8 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">Cases for diagnosis</span>"
      "titulo" => "Erythematous Papules on the Arm of a Mastectomy Patient"
      "tienePdf" => "en"
      "tieneTextoCompleto" => 0
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "231"
          "paginaFinal" => "232"
        ]
      ]
      "contienePdf" => array:1 [
        "en" => true
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "A&#46; Lucas, I&#46; Betlloch"
          "autores" => array:2 [
            0 => array:2 [
              "nombre" => "A&#46;"
              "apellidos" => "Lucas"
            ]
            1 => array:2 [
              "nombre" => "I&#46;"
              "apellidos" => "Betlloch"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "en"
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219009700502?idApp=UINPBA000044"
    "url" => "/15782190/0000010000000003/v1_201304241451/S1578219009700502/v1_201304241451/en/main.assets"
  ]
  "itemAnterior" => array:18 [
    "pii" => "S1578219009700484"
    "issn" => "15782190"
    "doi" => "10.1016/S1578-2190(09)70048-4"
    "estado" => "S300"
    "fechaPublicacion" => "2009-04-01"
    "aid" => "70048"
    "copyright" => "Academia Espa&#241;ola de Dermatolog&#237;a y Venereolog&#237;a and Elsevier Espa&#241;a&#44; S&#46;L&#46;"
    "documento" => "article"
    "crossmark" => 0
    "subdocumento" => "sco"
    "cita" => "Actas Dermosifiliogr. 2009;100:222-6"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:2 [
      "total" => 3182
      "formatos" => array:3 [
        "EPUB" => 43
        "HTML" => 1825
        "PDF" => 1314
      ]
    ]
    "en" => array:11 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">Case reports</span>"
      "titulo" => "Cerebrotendinous Xanthomatosis&#58; Report of 4 Patients"
      "tienePdf" => "en"
      "tieneTextoCompleto" => 0
      "tieneResumen" => array:2 [
        0 => "en"
        1 => "es"
      ]
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "222"
          "paginaFinal" => "226"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "es" => array:1 [
          "titulo" => "Xantomatosis Cerebrotendinosa&#58; Descripci&#243;n de 4 Casos"
        ]
      ]
      "contieneResumen" => array:2 [
        "en" => true
        "es" => true
      ]
      "contienePdf" => array:1 [
        "en" => true
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "C&#46; Ferr&#225;ndiz-Pulido, R&#46; Bartralot, M&#46; Gir&#243;s, P&#46; Bassas, C&#46; Heras, D&#46; Bodet, R&#46; Savall, V&#46; Garc&#237;a-Patos"
          "autores" => array:8 [
            0 => array:2 [
              "nombre" => "C&#46;"
              "apellidos" => "Ferr&#225;ndiz-Pulido"
            ]
            1 => array:2 [
              "nombre" => "R&#46;"
              "apellidos" => "Bartralot"
            ]
            2 => array:2 [
              "nombre" => "M&#46;"
              "apellidos" => "Gir&#243;s"
            ]
            3 => array:2 [
              "nombre" => "P&#46;"
              "apellidos" => "Bassas"
            ]
            4 => array:2 [
              "nombre" => "C&#46;"
              "apellidos" => "Heras"
            ]
            5 => array:2 [
              "nombre" => "D&#46;"
              "apellidos" => "Bodet"
            ]
            6 => array:2 [
              "nombre" => "R&#46;"
              "apellidos" => "Savall"
            ]
            7 => array:2 [
              "nombre" => "V&#46;"
              "apellidos" => "Garc&#237;a-Patos"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "en"
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219009700484?idApp=UINPBA000044"
    "url" => "/15782190/0000010000000003/v1_201304241451/S1578219009700484/v1_201304241451/en/main.assets"
  ]
  "en" => array:14 [
    "idiomaDefecto" => true
    "cabecera" => "<span class="elsevierStyleTextfn">Case reports</span>"
    "titulo" => "Birt-Hogg-Dub&#233; Syndrome in a Patient With Cutaneous Symptoms and a c&#46;1429 C&#62;T&#59; p&#46;R477X Mutation in Exon 12 of the Folliculin Gene"
    "tieneTextoCompleto" => 0
    "paginas" => array:1 [
      0 => array:2 [
        "paginaInicial" => "227"
        "paginaFinal" => "230"
      ]
    ]
    "autores" => array:1 [
      0 => array:4 [
        "autoresLista" => "I&#46; Fuertes, J&#46;M&#46; Mascar&#243;-Galy, J&#46; Ferrando"
        "autores" => array:3 [
          0 => array:4 [
            "nombre" => "I&#46;"
            "apellidos" => "Fuertes"
            "email" => array:1 [
              0 => "tressoles8113&#64;hotmail&#46;com"
            ]
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">¿</span>"
                "identificador" => "cor1"
              ]
            ]
          ]
          1 => array:2 [
            "nombre" => "J&#46;M&#46;"
            "apellidos" => "Mascar&#243;-Galy"
          ]
          2 => array:2 [
            "nombre" => "J&#46;"
            "apellidos" => "Ferrando"
          ]
        ]
        "afiliaciones" => array:1 [
          0 => array:1 [
            "entidad" => "Servicio de Dermatolog&#237;a&#44; Hospital Cl&#237;nic&#44; Universidad de Barcelona&#44; Barcelona&#44; Spain"
          ]
        ]
        "correspondencia" => array:1 [
          0 => array:3 [
            "identificador" => "cor1"
            "etiqueta" => "&#8270;"
            "correspondencia" => "Correspondencia&#58; Servicio de Dermatolog&#237;a&#44; Hospital Cl&#237;nic&#44; C&#47;Villarroel&#44; 170&#44; 08036 Barcelona&#44; Spain&#46;"
          ]
        ]
      ]
    ]
    "titulosAlternativos" => array:1 [
      "es" => array:1 [
        "titulo" => "S&#237;ndrome de Birt-Hogg-Dub&#233;&#44; en un Paciente con Cl&#237;nica Cut&#225;nea y Mutaci&#243;n en el Ex&#243;n 12 del Gen BHD&#58; c&#46;1429 C&#62; T&#59; p&#46;R477X"
      ]
    ]
    "pdfFichero" => "main.pdf"
    "tienePdf" => true
    "fechaAceptado" => "2008-07-07"
    "PalabrasClave" => array:2 [
      "en" => array:1 [
        0 => array:4 [
          "clase" => "keyword"
          "titulo" => "Key words"
          "identificador" => "xpalclavsec84422"
          "palabras" => array:3 [
            0 => "Birt-Hogg-Dub&#233; syndrome"
            1 => "fibrofolliculoma"
            2 => "folliculin gene"
          ]
        ]
      ]
      "es" => array:1 [
        0 => array:4 [
          "clase" => "keyword"
          "titulo" => "Palabras clave"
          "identificador" => "xpalclavsec84421"
          "palabras" => array:3 [
            0 => "s&#237;ndrome de Birt-Hogg-Dub&#233;"
            1 => "fibrofoliculoma"
            2 => "gen FCLN"
          ]
        ]
      ]
    ]
    "tieneResumen" => true
    "resumen" => array:2 [
      "en" => array:2 [
        "titulo" => "Abstract"
        "resumen" => "<p class="elsevierStyleSimplePara elsevierViewall">Birt-Hogg-Dub&#233; syndrome is an autosomal dominant genodermatosis characterized by the presence of fibrofolliculomas&#44; renal cancer&#44; pulmonary cysts&#44; and spontaneous pneumothorax&#46; Recently&#44; the folliculin gene responsible for this process has been identified&#44; located on the short arm of chromosome 17&#46; We present the case of a 49-year-old man with multiple whitish papules on the face&#44; neck&#44; and retroauricular area&#46; Histology was compatible with fibrofolliculoma and genetic study showed a pathogenic mutation of the folliculin gene&#46;</p>"
      ]
      "es" => array:2 [
        "titulo" => "Resumen"
        "resumen" => "<p class="elsevierStyleSimplePara elsevierViewall">El s&#237;ndrome de Birt-Hogg-Dub&#233; es una genodermatosis de herencia autos&#243;mica dominantecaracterizada por la presencia de fibrofoliculomas&#44; c&#225;ncer renal&#44; quistes pulmonares y pneumot&#243;rax espont&#225;neo&#46; Recientemente ha sido identificado el gen FCLN&#44; responsable de este proceso&#44; localizado en el brazo corto del cromosoma 17&#46; Presentamos el caso de un var&#243;n de 49 a&#241;os&#44; con m&#250;ltiples p&#225;pulas blanquecinas en la cara&#44; el cuello y el &#225;rea retroauricular&#46; La histolog&#237;a fue compatible con fibrofoliculoma y el estudio gen&#233;tico demostr&#243; una mutaci&#243;n patog&#233;nica en el gen FCLN&#46;</p>"
      ]
    ]
    "bibliografia" => array:2 [
      "titulo" => "References"
      "seccion" => array:1 [
        0 => array:1 [
          "bibliografiaReferencia" => array:24 [
            0 => array:3 [
              "identificador" => "bib1"
              "etiqueta" => "1&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Germline BHD-mutation spectrum and phenotype analysis of a large cohort of families with Birt-Hogg-Dub&#233; syndrome"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "L&#46;S&#46; Schmidt"
                            1 => "M&#46;L&#46; Nickerson"
                            2 => "M&#46;B&#46; Warren"
                            3 => "G&#46;M&#46; Glenn"
                            4 => "J&#46;R&#46; Toro"
                            5 => "M&#46;J&#46; Merino"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1086/430842"
                      "Revista" => array:6 [
                        "tituloSerie" => "Am J Hum Genet"
                        "fecha" => "2005"
                        "volumen" => "76"
                        "paginaInicial" => "1023"
                        "paginaFinal" => "1033"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15852235"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            1 => array:3 [
              "identificador" => "bib2"
              "etiqueta" => "2&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Hereditary multiple fibrofolliculomas with trichodiscomas and acrochordons"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "A&#46;R&#46; Birt"
                            1 => "G&#46;R&#46; Hogg"
                            2 => "J&#46; Dub&#233;"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Arch Dermatol"
                        "fecha" => "1977"
                        "volumen" => "113"
                        "paginaInicial" => "1674"
                        "paginaFinal" => "1677"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/596896"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            2 => array:3 [
              "identificador" => "bib3"
              "etiqueta" => "3&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Fibrofolliculoma&#44; trichodiscoma and Birt-Hogg-Dub&#233; Syndrome"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "C&#46; Steffen"
                            1 => "A&#46;B&#46; Ackerman"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "LibroEditado" => array:4 [
                        "titulo" => "Neoplasm with sebaceous differentiation"
                        "paginaInicial" => "205"
                        "paginaFinal" => "237"
                        "serieFecha" => "1994"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            3 => array:3 [
              "identificador" => "bib4"
              "etiqueta" => "4&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Hereditary multiple fibrofolliculomas&#44; trichodiscomas and acrochordons&#58; syndrome of Birt-Hogg-Dub&#233;"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "M&#46; Scalvenzi"
                            1 => "G&#46; Argenziano"
                            2 => "E&#46; Sammarco"
                            3 => "M&#46; Delfino"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "J Eur Acad Dermatol Venereol"
                        "fecha" => "1998"
                        "volumen" => "11"
                        "paginaInicial" => "45"
                        "paginaFinal" => "47"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9731965"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            4 => array:3 [
              "identificador" => "bib5"
              "etiqueta" => "5&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Acrochordons are not a component of the Birt-Hogg-Dub&#233; syndrome&#58; does this syndrome exist&#63; Case reports and review of the literature"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "C&#46; De la Torre"
                            1 => "C&#46; Ocampo"
                            2 => "I&#46;G&#46; Doval"
                            3 => "A&#46; Losada"
                            4 => "M&#46;J&#46; Cruces"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Am J Dermatopathol"
                        "fecha" => "1999"
                        "volumen" => "21"
                        "paginaInicial" => "369"
                        "paginaFinal" => "374"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10446780"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            5 => array:3 [
              "identificador" => "bib6"
              "etiqueta" => "6&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Fibrofolliculoma&#44; trichodiscoma and acrochordon&#46; The Birt-Hogg-Dub&#233; syndrome"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "L&#46; Balus"
                            1 => "M&#46; Fazio"
                            2 => "G&#46; Sacerdoti"
                            3 => "A&#46; Morrone"
                            4 => "W&#46; Marmo"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Ann Dermatol Venereol"
                        "fecha" => "1983"
                        "volumen" => "110"
                        "paginaInicial" => "601"
                        "paginaFinal" => "609"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/6660760"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            6 => array:3 [
              "identificador" => "bib7"
              "etiqueta" => "7&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Multiple fibrofolliculomas with trichodiscomas and acrochordons"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "W&#46;H&#46; Fujita"
                            1 => "R&#46;J&#46; Barr"
                            2 => "J&#46;L&#46; Headley"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Arch Dermatol"
                        "fecha" => "1981"
                        "volumen" => "117"
                        "paginaInicial" => "32"
                        "paginaFinal" => "35"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/7458379"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            7 => array:3 [
              "identificador" => "bib8"
              "etiqueta" => "8&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Birt-Hogg-Dub&#233; syndrome&#58; mapping of a novel hereditary neoplasia gene to chromosome 17p12-q11&#46;2"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "S&#46;K&#46; Khoo"
                            1 => "M&#46; Bradley"
                            2 => "F&#46;K&#46; Wong"
                            3 => "M&#46;A&#46; Hedblad"
                            4 => "M&#46; Nordenskj&#246;ld"
                            5 => "B&#46;T&#46; Teh"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1038/sj.onc.1204703"
                      "Revista" => array:6 [
                        "tituloSerie" => "Oncogene"
                        "fecha" => "2001"
                        "volumen" => "20"
                        "paginaInicial" => "5239"
                        "paginaFinal" => "5242"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11526515"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            8 => array:3 [
              "identificador" => "bib9"
              "etiqueta" => "9&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Birt-Hogg-Dub&#233; syndrome&#44; a genodermatosis associated with spontaneous pneumothorax and kidney neoplasia&#44; maps to chromosome 17p11&#46;2"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "L&#46;S&#46; Schmidt"
                            1 => "M&#46;B&#46; Warren"
                            2 => "M&#46;L&#46; Nickerson"
                            3 => "G&#46; Weirich"
                            4 => "V&#46; Matrosova"
                            5 => "J&#46;R&#46; Toro"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1086/323744"
                      "Revista" => array:6 [
                        "tituloSerie" => "Am J Hum Genet"
                        "fecha" => "2001"
                        "volumen" => "69"
                        "paginaInicial" => "876"
                        "paginaFinal" => "882"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11533913"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            9 => array:3 [
              "identificador" => "bib10"
              "etiqueta" => "10&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Mutations in a novel gene lead to kidney tumors&#44; lung wall defects&#44; and benign tumors of the hair follicle in patients with the Birt-Hogg-Dub&#233; syndrome"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "M&#46;L&#46; Nickerson"
                            1 => "M&#46;B&#46; Warren"
                            2 => "J&#46;R&#46; Toro"
                            3 => "V&#46; Matrosova"
                            4 => "G&#46; Glenn"
                            5 => "M&#46;L&#46; Turner"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Cancer Cell"
                        "fecha" => "2002"
                        "volumen" => "2"
                        "paginaInicial" => "157"
                        "paginaFinal" => "164"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12204536"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            10 => array:3 [
              "identificador" => "bib11"
              "etiqueta" => "11&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "A mutation in the canine BHD gene is associated with hereditary multifocal renal cystadenocarcinoma and nodular dermatofibrosis in the German Shepherd dog"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "F&#46; Lingaas"
                            1 => "K&#46;E&#46; Comstock"
                            2 => "E&#46;F&#46; Kirkness"
                            3 => "A&#46; S&#248;rensen"
                            4 => "T&#46; Aarskaug"
                            5 => "C&#46; Hitte"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1093/hmg/ddg336"
                      "Revista" => array:6 [
                        "tituloSerie" => "Hum Mol Genet"
                        "fecha" => "2003"
                        "volumen" => "12"
                        "paginaInicial" => "3043"
                        "paginaFinal" => "3053"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/14532326"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            11 => array:3 [
              "identificador" => "bib12"
              "etiqueta" => "12&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Natural history of the Nihon rat model of BHD"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "K&#46; Okimoto"
                            1 => "M&#46; Kouchi"
                            2 => "I&#46; Matsumoto"
                            3 => "J&#46; Sakurai"
                            4 => "T&#46; Kobayashi"
                            5 => "O&#46; Hino"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Curr Mol Med"
                        "fecha" => "2004"
                        "volumen" => "4"
                        "paginaInicial" => "887"
                        "paginaFinal" => "893"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15579036"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            12 => array:3 [
              "identificador" => "bib13"
              "etiqueta" => "13&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Birt-Hogg-Dub&#233; syndrome&#58; a novel marker of kidney neoplasia"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "J&#46;R&#46; Toro"
                            1 => "G&#46; Glenn"
                            2 => "P&#46; Duray"
                            3 => "T&#46; Darling"
                            4 => "G&#46; Weirich"
                            5 => "B&#46; Zbar"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Arch Dermatol"
                        "fecha" => "1999"
                        "volumen" => "135"
                        "paginaInicial" => "1195"
                        "paginaFinal" => "1202"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10522666"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            13 => array:3 [
              "identificador" => "bib14"
              "etiqueta" => "14&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Risk of renal and colonic neoplasms and spontaneous pneumothorax in the Birt-Hogg-Dub&#233; syndrome"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "B&#46; Zbar"
                            1 => "W&#46;G&#46; Alvord"
                            2 => "G&#46; Glenn"
                            3 => "M&#46; Turner"
                            4 => "C&#46;P&#46; Pavlovich"
                            5 => "L&#46; Schmidt"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Cancer Epidemiol Biomarkers Prev"
                        "fecha" => "2002"
                        "volumen" => "11"
                        "paginaInicial" => "393"
                        "paginaFinal" => "400"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11927500"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            14 => array:3 [
              "identificador" => "bib15"
              "etiqueta" => "15&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Bilateral renal cell carcinoma in the Birt-Hogg-Dub&#233; syndrome"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "J&#46;S&#46; Roth"
                            1 => "A&#46;D&#46; Rabinowitz"
                            2 => "M&#46; Benson"
                            3 => "M&#46;E&#46; Grossman"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "J Am Acad Dermatol"
                        "fecha" => "1993"
                        "volumen" => "29"
                        "paginaInicial" => "1055"
                        "paginaFinal" => "1056"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8245249"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            15 => array:3 [
              "identificador" => "bib16"
              "etiqueta" => "16&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Pleuropulmonary pathology of Birt-Hogg-Dub&#233; syndrome"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "K&#46;J&#46; Butnor"
                            1 => "D&#46;G&#46; Guinee Jr"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1097/01.pas.0000183571.17011.06"
                      "Revista" => array:6 [
                        "tituloSerie" => "Am J Surg Pathol"
                        "fecha" => "2006"
                        "volumen" => "30"
                        "paginaInicial" => "395"
                        "paginaFinal" => "399"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16538061"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            16 => array:3 [
              "identificador" => "bib17"
              "etiqueta" => "17&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Renal oncocytosis&#58; a morphologic study of fourteen cases"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "S&#46;K&#46; Tickoo"
                            1 => "V&#46;E&#46; Reuter"
                            2 => "M&#46;B&#46; Amin"
                            3 => "J&#46;R&#46; Srigley"
                            4 => "J&#46;I&#46; Epstein"
                            5 => "K&#46;W&#46; Min"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Am J Surg Pathol"
                        "fecha" => "1999"
                        "volumen" => "23"
                        "paginaInicial" => "1094"
                        "paginaFinal" => "1101"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10478670"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            17 => array:3 [
              "identificador" => "bib18"
              "etiqueta" => "18&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Comparative genomic hybridization analysis of renal oncocytomas&#44; chromophobe renal cell carcinomas&#44; and tumors with hybrid histology&#58; hybrid oncocytic tumors"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "G&#46; Weirich"
                            1 => "K&#46; Junker"
                            2 => "P&#46;G&#46;O&#46; Salles"
                            3 => "S&#46;D&#46; Lim"
                            4 => "M&#46;N&#46; de Peralta-Venturina"
                            5 => "I&#46; Alvarado-Cabrero"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:4 [
                        "tituloSerie" => "Mod Pathol"
                        "fecha" => "2002"
                        "volumen" => "15"
                        "paginaInicial" => "186"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            18 => array:3 [
              "identificador" => "bib19"
              "etiqueta" => "19&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Evaluation and management of renal tumors in the Birt-Hogg-Dub&#233; syndrome"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "C&#46;P&#46; Pavlovich"
                            1 => "R&#46;L&#46; Grubb 3rd"
                            2 => "K&#46; Hurley"
                            3 => "G&#46;M&#46; Glenn"
                            4 => "J&#46; Toro"
                            5 => "L&#46;S&#46; Schmidt"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1097/01.ju.0000154629.45832.30"
                      "Revista" => array:6 [
                        "tituloSerie" => "J Urol"
                        "fecha" => "2005"
                        "volumen" => "173"
                        "paginaInicial" => "1482"
                        "paginaFinal" => "1486"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15821464"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            19 => array:3 [
              "identificador" => "bib20"
              "etiqueta" => "20&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Understanding familial and non-familial renal cell cancer"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "D&#46; Bodmer"
                            1 => "W&#46; van den Hurk"
                            2 => "J&#46;J&#46; van Groningen"
                            3 => "M&#46;J&#46; Eleveld"
                            4 => "G&#46;J&#46; Martens"
                            5 => "M&#46;A&#46; Weterman"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Hum Mol Genet"
                        "fecha" => "2002"
                        "volumen" => "11"
                        "paginaInicial" => "2489"
                        "paginaFinal" => "2498"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12351585"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            20 => array:3 [
              "identificador" => "bib21"
              "etiqueta" => "21&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Renal tumors in the Birt-Hogg-Dub&#233; syndrome"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "C&#46;P&#46; Pavlovich"
                            1 => "M&#46;M&#46; Walther"
                            2 => "R&#46;A&#46; Eyler"
                            3 => "S&#46;M&#46; Hewitt"
                            4 => "B&#46; Zbar"
                            5 => "W&#46;M&#46; Linehan"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Am J Surg Pathol"
                        "fecha" => "2002"
                        "volumen" => "26"
                        "paginaInicial" => "1542"
                        "paginaFinal" => "1552"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12459621"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            21 => array:3 [
              "identificador" => "bib22"
              "etiqueta" => "22&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Letter&#58; hyfrecation and curettage as a treatment for fibrofolliculomas in Birt-Hogg-Dub&#233; syndrome"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "P&#46;B&#46; Farant"
                            1 => "R&#46; Emerson"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1111/j.1524-4725.2007.33270.x"
                      "Revista" => array:6 [
                        "tituloSerie" => "Dermatol Surg"
                        "fecha" => "2007"
                        "volumen" => "33"
                        "paginaInicial" => "1287"
                        "paginaFinal" => "1288"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/17903168"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            22 => array:3 [
              "identificador" => "bib23"
              "etiqueta" => "23&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Birt-Hogg-Dube syndrome&#58; treatment of cutaneous manifestations with laser skin resurfacing"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "C&#46;I&#46; Jacob"
                            1 => "J&#46;S&#46; Dover"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Arch Dermatol"
                        "fecha" => "2001"
                        "volumen" => "137"
                        "paginaInicial" => "98"
                        "paginaFinal" => "99"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11176677"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            23 => array:3 [
              "identificador" => "bib24"
              "etiqueta" => "24&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Tricodiscomas m&#250;ltiples familiares"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "M&#46;M&#46; Alsina"
                            1 => "J&#46; Ferrando"
                            2 => "J&#46;A&#46; Bomb&#237;"
                            3 => "A&#46; Pou"
                            4 => "H&#46; Torras"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Med Cutan Iber Lat Am"
                        "fecha" => "1990"
                        "volumen" => "18"
                        "paginaInicial" => "30"
                        "paginaFinal" => "34"
                      ]
                    ]
                  ]
                ]
              ]
            ]
          ]
        ]
      ]
    ]
  ]
  "idiomaDefecto" => "en"
  "url" => "/15782190/0000010000000003/v1_201304241451/S1578219009700496/v1_201304241451/en/main.assets"
  "Apartado" => array:4 [
    "identificador" => "6183"
    "tipo" => "SECCION"
    "en" => array:2 [
      "titulo" => "Case Reports"
      "idiomaDefecto" => true
    ]
    "idiomaDefecto" => "en"
  ]
  "PDF" => "https://static.elsevier.es/multimedia/15782190/0000010000000003/v1_201304241451/S1578219009700496/v1_201304241451/en/main.pdf?idApp=UINPBA000044&text.app=https://actasdermo.org/"
  "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219009700496?idApp=UINPBA000044"
]
Compartir
Información de la revista

Estadísticas

Siga este enlace para acceder al texto completo del artículo

Case reports
Birt-Hogg-Dubé Syndrome in a Patient With Cutaneous Symptoms and a c.1429 C>T; p.R477X Mutation in Exon 12 of the Folliculin Gene
Síndrome de Birt-Hogg-Dubé, en un Paciente con Clínica Cutánea y Mutación en el Exón 12 del Gen BHD: c.1429 C> T; p.R477X
I. Fuertes
Autor para correspondencia
tressoles8113@hotmail.com

Correspondencia: Servicio de Dermatología, Hospital Clínic, C/Villarroel, 170, 08036 Barcelona, Spain.
, J.M. Mascaró-Galy, J. Ferrando
Servicio de Dermatología, Hospital Clínic, Universidad de Barcelona, Barcelona, Spain
Leído
6819
Veces
se ha leído el artículo
3205
Total PDF
3614
Total HTML
Compartir estadísticas
 array:23 [
  "pii" => "S1578219009700496"
  "issn" => "15782190"
  "doi" => "10.1016/S1578-2190(09)70049-6"
  "estado" => "S300"
  "fechaPublicacion" => "2009-04-01"
  "aid" => "70049"
  "copyright" => "Academia Espa&#241;ola de Dermatolog&#237;a y Venereolog&#237;a and Elsevier Espa&#241;a&#44; S&#46;L&#46;"
  "copyrightAnyo" => "2009"
  "documento" => "article"
  "crossmark" => 0
  "subdocumento" => "sco"
  "cita" => "Actas Dermosifiliogr. 2009;100:227-30"
  "abierto" => array:3 [
    "ES" => true
    "ES2" => true
    "LATM" => true
  ]
  "gratuito" => true
  "lecturas" => array:2 [
    "total" => 2346
    "formatos" => array:3 [
      "EPUB" => 35
      "HTML" => 1556
      "PDF" => 755
    ]
  ]
  "itemSiguiente" => array:18 [
    "pii" => "S1578219009700502"
    "issn" => "15782190"
    "doi" => "10.1016/S1578-2190(09)70050-2"
    "estado" => "S300"
    "fechaPublicacion" => "2009-04-01"
    "aid" => "70050"
    "copyright" => "Academia Espa&#241;ola de Dermatolog&#237;a y Venereolog&#237;a and Elsevier Espa&#241;a&#44; S&#46;L&#46;"
    "documento" => "article"
    "crossmark" => 0
    "subdocumento" => "sco"
    "cita" => "Actas Dermosifiliogr. 2009;100:231-2"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:2 [
      "total" => 2307
      "formatos" => array:3 [
        "EPUB" => 38
        "HTML" => 1299
        "PDF" => 970
      ]
    ]
    "en" => array:8 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">Cases for diagnosis</span>"
      "titulo" => "Erythematous Papules on the Arm of a Mastectomy Patient"
      "tienePdf" => "en"
      "tieneTextoCompleto" => 0
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "231"
          "paginaFinal" => "232"
        ]
      ]
      "contienePdf" => array:1 [
        "en" => true
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "A&#46; Lucas, I&#46; Betlloch"
          "autores" => array:2 [
            0 => array:2 [
              "nombre" => "A&#46;"
              "apellidos" => "Lucas"
            ]
            1 => array:2 [
              "nombre" => "I&#46;"
              "apellidos" => "Betlloch"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "en"
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219009700502?idApp=UINPBA000044"
    "url" => "/15782190/0000010000000003/v1_201304241451/S1578219009700502/v1_201304241451/en/main.assets"
  ]
  "itemAnterior" => array:18 [
    "pii" => "S1578219009700484"
    "issn" => "15782190"
    "doi" => "10.1016/S1578-2190(09)70048-4"
    "estado" => "S300"
    "fechaPublicacion" => "2009-04-01"
    "aid" => "70048"
    "copyright" => "Academia Espa&#241;ola de Dermatolog&#237;a y Venereolog&#237;a and Elsevier Espa&#241;a&#44; S&#46;L&#46;"
    "documento" => "article"
    "crossmark" => 0
    "subdocumento" => "sco"
    "cita" => "Actas Dermosifiliogr. 2009;100:222-6"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:2 [
      "total" => 3182
      "formatos" => array:3 [
        "EPUB" => 43
        "HTML" => 1825
        "PDF" => 1314
      ]
    ]
    "en" => array:11 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">Case reports</span>"
      "titulo" => "Cerebrotendinous Xanthomatosis&#58; Report of 4 Patients"
      "tienePdf" => "en"
      "tieneTextoCompleto" => 0
      "tieneResumen" => array:2 [
        0 => "en"
        1 => "es"
      ]
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "222"
          "paginaFinal" => "226"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "es" => array:1 [
          "titulo" => "Xantomatosis Cerebrotendinosa&#58; Descripci&#243;n de 4 Casos"
        ]
      ]
      "contieneResumen" => array:2 [
        "en" => true
        "es" => true
      ]
      "contienePdf" => array:1 [
        "en" => true
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "C&#46; Ferr&#225;ndiz-Pulido, R&#46; Bartralot, M&#46; Gir&#243;s, P&#46; Bassas, C&#46; Heras, D&#46; Bodet, R&#46; Savall, V&#46; Garc&#237;a-Patos"
          "autores" => array:8 [
            0 => array:2 [
              "nombre" => "C&#46;"
              "apellidos" => "Ferr&#225;ndiz-Pulido"
            ]
            1 => array:2 [
              "nombre" => "R&#46;"
              "apellidos" => "Bartralot"
            ]
            2 => array:2 [
              "nombre" => "M&#46;"
              "apellidos" => "Gir&#243;s"
            ]
            3 => array:2 [
              "nombre" => "P&#46;"
              "apellidos" => "Bassas"
            ]
            4 => array:2 [
              "nombre" => "C&#46;"
              "apellidos" => "Heras"
            ]
            5 => array:2 [
              "nombre" => "D&#46;"
              "apellidos" => "Bodet"
            ]
            6 => array:2 [
              "nombre" => "R&#46;"
              "apellidos" => "Savall"
            ]
            7 => array:2 [
              "nombre" => "V&#46;"
              "apellidos" => "Garc&#237;a-Patos"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "en"
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219009700484?idApp=UINPBA000044"
    "url" => "/15782190/0000010000000003/v1_201304241451/S1578219009700484/v1_201304241451/en/main.assets"
  ]
  "en" => array:14 [
    "idiomaDefecto" => true
    "cabecera" => "<span class="elsevierStyleTextfn">Case reports</span>"
    "titulo" => "Birt-Hogg-Dub&#233; Syndrome in a Patient With Cutaneous Symptoms and a c&#46;1429 C&#62;T&#59; p&#46;R477X Mutation in Exon 12 of the Folliculin Gene"
    "tieneTextoCompleto" => 0
    "paginas" => array:1 [
      0 => array:2 [
        "paginaInicial" => "227"
        "paginaFinal" => "230"
      ]
    ]
    "autores" => array:1 [
      0 => array:4 [
        "autoresLista" => "I&#46; Fuertes, J&#46;M&#46; Mascar&#243;-Galy, J&#46; Ferrando"
        "autores" => array:3 [
          0 => array:4 [
            "nombre" => "I&#46;"
            "apellidos" => "Fuertes"
            "email" => array:1 [
              0 => "tressoles8113&#64;hotmail&#46;com"
            ]
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">¿</span>"
                "identificador" => "cor1"
              ]
            ]
          ]
          1 => array:2 [
            "nombre" => "J&#46;M&#46;"
            "apellidos" => "Mascar&#243;-Galy"
          ]
          2 => array:2 [
            "nombre" => "J&#46;"
            "apellidos" => "Ferrando"
          ]
        ]
        "afiliaciones" => array:1 [
          0 => array:1 [
            "entidad" => "Servicio de Dermatolog&#237;a&#44; Hospital Cl&#237;nic&#44; Universidad de Barcelona&#44; Barcelona&#44; Spain"
          ]
        ]
        "correspondencia" => array:1 [
          0 => array:3 [
            "identificador" => "cor1"
            "etiqueta" => "&#8270;"
            "correspondencia" => "Correspondencia&#58; Servicio de Dermatolog&#237;a&#44; Hospital Cl&#237;nic&#44; C&#47;Villarroel&#44; 170&#44; 08036 Barcelona&#44; Spain&#46;"
          ]
        ]
      ]
    ]
    "titulosAlternativos" => array:1 [
      "es" => array:1 [
        "titulo" => "S&#237;ndrome de Birt-Hogg-Dub&#233;&#44; en un Paciente con Cl&#237;nica Cut&#225;nea y Mutaci&#243;n en el Ex&#243;n 12 del Gen BHD&#58; c&#46;1429 C&#62; T&#59; p&#46;R477X"
      ]
    ]
    "pdfFichero" => "main.pdf"
    "tienePdf" => true
    "fechaAceptado" => "2008-07-07"
    "PalabrasClave" => array:2 [
      "en" => array:1 [
        0 => array:4 [
          "clase" => "keyword"
          "titulo" => "Key words"
          "identificador" => "xpalclavsec84422"
          "palabras" => array:3 [
            0 => "Birt-Hogg-Dub&#233; syndrome"
            1 => "fibrofolliculoma"
            2 => "folliculin gene"
          ]
        ]
      ]
      "es" => array:1 [
        0 => array:4 [
          "clase" => "keyword"
          "titulo" => "Palabras clave"
          "identificador" => "xpalclavsec84421"
          "palabras" => array:3 [
            0 => "s&#237;ndrome de Birt-Hogg-Dub&#233;"
            1 => "fibrofoliculoma"
            2 => "gen FCLN"
          ]
        ]
      ]
    ]
    "tieneResumen" => true
    "resumen" => array:2 [
      "en" => array:2 [
        "titulo" => "Abstract"
        "resumen" => "<p class="elsevierStyleSimplePara elsevierViewall">Birt-Hogg-Dub&#233; syndrome is an autosomal dominant genodermatosis characterized by the presence of fibrofolliculomas&#44; renal cancer&#44; pulmonary cysts&#44; and spontaneous pneumothorax&#46; Recently&#44; the folliculin gene responsible for this process has been identified&#44; located on the short arm of chromosome 17&#46; We present the case of a 49-year-old man with multiple whitish papules on the face&#44; neck&#44; and retroauricular area&#46; Histology was compatible with fibrofolliculoma and genetic study showed a pathogenic mutation of the folliculin gene&#46;</p>"
      ]
      "es" => array:2 [
        "titulo" => "Resumen"
        "resumen" => "<p class="elsevierStyleSimplePara elsevierViewall">El s&#237;ndrome de Birt-Hogg-Dub&#233; es una genodermatosis de herencia autos&#243;mica dominantecaracterizada por la presencia de fibrofoliculomas&#44; c&#225;ncer renal&#44; quistes pulmonares y pneumot&#243;rax espont&#225;neo&#46; Recientemente ha sido identificado el gen FCLN&#44; responsable de este proceso&#44; localizado en el brazo corto del cromosoma 17&#46; Presentamos el caso de un var&#243;n de 49 a&#241;os&#44; con m&#250;ltiples p&#225;pulas blanquecinas en la cara&#44; el cuello y el &#225;rea retroauricular&#46; La histolog&#237;a fue compatible con fibrofoliculoma y el estudio gen&#233;tico demostr&#243; una mutaci&#243;n patog&#233;nica en el gen FCLN&#46;</p>"
      ]
    ]
    "bibliografia" => array:2 [
      "titulo" => "References"
      "seccion" => array:1 [
        0 => array:1 [
          "bibliografiaReferencia" => array:24 [
            0 => array:3 [
              "identificador" => "bib1"
              "etiqueta" => "1&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Germline BHD-mutation spectrum and phenotype analysis of a large cohort of families with Birt-Hogg-Dub&#233; syndrome"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "L&#46;S&#46; Schmidt"
                            1 => "M&#46;L&#46; Nickerson"
                            2 => "M&#46;B&#46; Warren"
                            3 => "G&#46;M&#46; Glenn"
                            4 => "J&#46;R&#46; Toro"
                            5 => "M&#46;J&#46; Merino"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1086/430842"
                      "Revista" => array:6 [
                        "tituloSerie" => "Am J Hum Genet"
                        "fecha" => "2005"
                        "volumen" => "76"
                        "paginaInicial" => "1023"
                        "paginaFinal" => "1033"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15852235"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            1 => array:3 [
              "identificador" => "bib2"
              "etiqueta" => "2&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Hereditary multiple fibrofolliculomas with trichodiscomas and acrochordons"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "A&#46;R&#46; Birt"
                            1 => "G&#46;R&#46; Hogg"
                            2 => "J&#46; Dub&#233;"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Arch Dermatol"
                        "fecha" => "1977"
                        "volumen" => "113"
                        "paginaInicial" => "1674"
                        "paginaFinal" => "1677"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/596896"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            2 => array:3 [
              "identificador" => "bib3"
              "etiqueta" => "3&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Fibrofolliculoma&#44; trichodiscoma and Birt-Hogg-Dub&#233; Syndrome"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "C&#46; Steffen"
                            1 => "A&#46;B&#46; Ackerman"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "LibroEditado" => array:4 [
                        "titulo" => "Neoplasm with sebaceous differentiation"
                        "paginaInicial" => "205"
                        "paginaFinal" => "237"
                        "serieFecha" => "1994"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            3 => array:3 [
              "identificador" => "bib4"
              "etiqueta" => "4&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Hereditary multiple fibrofolliculomas&#44; trichodiscomas and acrochordons&#58; syndrome of Birt-Hogg-Dub&#233;"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "M&#46; Scalvenzi"
                            1 => "G&#46; Argenziano"
                            2 => "E&#46; Sammarco"
                            3 => "M&#46; Delfino"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "J Eur Acad Dermatol Venereol"
                        "fecha" => "1998"
                        "volumen" => "11"
                        "paginaInicial" => "45"
                        "paginaFinal" => "47"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9731965"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            4 => array:3 [
              "identificador" => "bib5"
              "etiqueta" => "5&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Acrochordons are not a component of the Birt-Hogg-Dub&#233; syndrome&#58; does this syndrome exist&#63; Case reports and review of the literature"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "C&#46; De la Torre"
                            1 => "C&#46; Ocampo"
                            2 => "I&#46;G&#46; Doval"
                            3 => "A&#46; Losada"
                            4 => "M&#46;J&#46; Cruces"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Am J Dermatopathol"
                        "fecha" => "1999"
                        "volumen" => "21"
                        "paginaInicial" => "369"
                        "paginaFinal" => "374"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10446780"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            5 => array:3 [
              "identificador" => "bib6"
              "etiqueta" => "6&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Fibrofolliculoma&#44; trichodiscoma and acrochordon&#46; The Birt-Hogg-Dub&#233; syndrome"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "L&#46; Balus"
                            1 => "M&#46; Fazio"
                            2 => "G&#46; Sacerdoti"
                            3 => "A&#46; Morrone"
                            4 => "W&#46; Marmo"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Ann Dermatol Venereol"
                        "fecha" => "1983"
                        "volumen" => "110"
                        "paginaInicial" => "601"
                        "paginaFinal" => "609"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/6660760"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            6 => array:3 [
              "identificador" => "bib7"
              "etiqueta" => "7&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Multiple fibrofolliculomas with trichodiscomas and acrochordons"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "W&#46;H&#46; Fujita"
                            1 => "R&#46;J&#46; Barr"
                            2 => "J&#46;L&#46; Headley"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Arch Dermatol"
                        "fecha" => "1981"
                        "volumen" => "117"
                        "paginaInicial" => "32"
                        "paginaFinal" => "35"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/7458379"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            7 => array:3 [
              "identificador" => "bib8"
              "etiqueta" => "8&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Birt-Hogg-Dub&#233; syndrome&#58; mapping of a novel hereditary neoplasia gene to chromosome 17p12-q11&#46;2"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "S&#46;K&#46; Khoo"
                            1 => "M&#46; Bradley"
                            2 => "F&#46;K&#46; Wong"
                            3 => "M&#46;A&#46; Hedblad"
                            4 => "M&#46; Nordenskj&#246;ld"
                            5 => "B&#46;T&#46; Teh"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1038/sj.onc.1204703"
                      "Revista" => array:6 [
                        "tituloSerie" => "Oncogene"
                        "fecha" => "2001"
                        "volumen" => "20"
                        "paginaInicial" => "5239"
                        "paginaFinal" => "5242"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11526515"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            8 => array:3 [
              "identificador" => "bib9"
              "etiqueta" => "9&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Birt-Hogg-Dub&#233; syndrome&#44; a genodermatosis associated with spontaneous pneumothorax and kidney neoplasia&#44; maps to chromosome 17p11&#46;2"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "L&#46;S&#46; Schmidt"
                            1 => "M&#46;B&#46; Warren"
                            2 => "M&#46;L&#46; Nickerson"
                            3 => "G&#46; Weirich"
                            4 => "V&#46; Matrosova"
                            5 => "J&#46;R&#46; Toro"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1086/323744"
                      "Revista" => array:6 [
                        "tituloSerie" => "Am J Hum Genet"
                        "fecha" => "2001"
                        "volumen" => "69"
                        "paginaInicial" => "876"
                        "paginaFinal" => "882"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11533913"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            9 => array:3 [
              "identificador" => "bib10"
              "etiqueta" => "10&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Mutations in a novel gene lead to kidney tumors&#44; lung wall defects&#44; and benign tumors of the hair follicle in patients with the Birt-Hogg-Dub&#233; syndrome"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "M&#46;L&#46; Nickerson"
                            1 => "M&#46;B&#46; Warren"
                            2 => "J&#46;R&#46; Toro"
                            3 => "V&#46; Matrosova"
                            4 => "G&#46; Glenn"
                            5 => "M&#46;L&#46; Turner"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Cancer Cell"
                        "fecha" => "2002"
                        "volumen" => "2"
                        "paginaInicial" => "157"
                        "paginaFinal" => "164"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12204536"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            10 => array:3 [
              "identificador" => "bib11"
              "etiqueta" => "11&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "A mutation in the canine BHD gene is associated with hereditary multifocal renal cystadenocarcinoma and nodular dermatofibrosis in the German Shepherd dog"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "F&#46; Lingaas"
                            1 => "K&#46;E&#46; Comstock"
                            2 => "E&#46;F&#46; Kirkness"
                            3 => "A&#46; S&#248;rensen"
                            4 => "T&#46; Aarskaug"
                            5 => "C&#46; Hitte"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1093/hmg/ddg336"
                      "Revista" => array:6 [
                        "tituloSerie" => "Hum Mol Genet"
                        "fecha" => "2003"
                        "volumen" => "12"
                        "paginaInicial" => "3043"
                        "paginaFinal" => "3053"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/14532326"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            11 => array:3 [
              "identificador" => "bib12"
              "etiqueta" => "12&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Natural history of the Nihon rat model of BHD"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "K&#46; Okimoto"
                            1 => "M&#46; Kouchi"
                            2 => "I&#46; Matsumoto"
                            3 => "J&#46; Sakurai"
                            4 => "T&#46; Kobayashi"
                            5 => "O&#46; Hino"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Curr Mol Med"
                        "fecha" => "2004"
                        "volumen" => "4"
                        "paginaInicial" => "887"
                        "paginaFinal" => "893"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15579036"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            12 => array:3 [
              "identificador" => "bib13"
              "etiqueta" => "13&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Birt-Hogg-Dub&#233; syndrome&#58; a novel marker of kidney neoplasia"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "J&#46;R&#46; Toro"
                            1 => "G&#46; Glenn"
                            2 => "P&#46; Duray"
                            3 => "T&#46; Darling"
                            4 => "G&#46; Weirich"
                            5 => "B&#46; Zbar"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Arch Dermatol"
                        "fecha" => "1999"
                        "volumen" => "135"
                        "paginaInicial" => "1195"
                        "paginaFinal" => "1202"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10522666"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            13 => array:3 [
              "identificador" => "bib14"
              "etiqueta" => "14&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Risk of renal and colonic neoplasms and spontaneous pneumothorax in the Birt-Hogg-Dub&#233; syndrome"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "B&#46; Zbar"
                            1 => "W&#46;G&#46; Alvord"
                            2 => "G&#46; Glenn"
                            3 => "M&#46; Turner"
                            4 => "C&#46;P&#46; Pavlovich"
                            5 => "L&#46; Schmidt"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Cancer Epidemiol Biomarkers Prev"
                        "fecha" => "2002"
                        "volumen" => "11"
                        "paginaInicial" => "393"
                        "paginaFinal" => "400"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11927500"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            14 => array:3 [
              "identificador" => "bib15"
              "etiqueta" => "15&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Bilateral renal cell carcinoma in the Birt-Hogg-Dub&#233; syndrome"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "J&#46;S&#46; Roth"
                            1 => "A&#46;D&#46; Rabinowitz"
                            2 => "M&#46; Benson"
                            3 => "M&#46;E&#46; Grossman"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "J Am Acad Dermatol"
                        "fecha" => "1993"
                        "volumen" => "29"
                        "paginaInicial" => "1055"
                        "paginaFinal" => "1056"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8245249"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            15 => array:3 [
              "identificador" => "bib16"
              "etiqueta" => "16&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Pleuropulmonary pathology of Birt-Hogg-Dub&#233; syndrome"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "K&#46;J&#46; Butnor"
                            1 => "D&#46;G&#46; Guinee Jr"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1097/01.pas.0000183571.17011.06"
                      "Revista" => array:6 [
                        "tituloSerie" => "Am J Surg Pathol"
                        "fecha" => "2006"
                        "volumen" => "30"
                        "paginaInicial" => "395"
                        "paginaFinal" => "399"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16538061"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            16 => array:3 [
              "identificador" => "bib17"
              "etiqueta" => "17&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Renal oncocytosis&#58; a morphologic study of fourteen cases"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "S&#46;K&#46; Tickoo"
                            1 => "V&#46;E&#46; Reuter"
                            2 => "M&#46;B&#46; Amin"
                            3 => "J&#46;R&#46; Srigley"
                            4 => "J&#46;I&#46; Epstein"
                            5 => "K&#46;W&#46; Min"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Am J Surg Pathol"
                        "fecha" => "1999"
                        "volumen" => "23"
                        "paginaInicial" => "1094"
                        "paginaFinal" => "1101"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10478670"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            17 => array:3 [
              "identificador" => "bib18"
              "etiqueta" => "18&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Comparative genomic hybridization analysis of renal oncocytomas&#44; chromophobe renal cell carcinomas&#44; and tumors with hybrid histology&#58; hybrid oncocytic tumors"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "G&#46; Weirich"
                            1 => "K&#46; Junker"
                            2 => "P&#46;G&#46;O&#46; Salles"
                            3 => "S&#46;D&#46; Lim"
                            4 => "M&#46;N&#46; de Peralta-Venturina"
                            5 => "I&#46; Alvarado-Cabrero"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:4 [
                        "tituloSerie" => "Mod Pathol"
                        "fecha" => "2002"
                        "volumen" => "15"
                        "paginaInicial" => "186"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            18 => array:3 [
              "identificador" => "bib19"
              "etiqueta" => "19&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Evaluation and management of renal tumors in the Birt-Hogg-Dub&#233; syndrome"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "C&#46;P&#46; Pavlovich"
                            1 => "R&#46;L&#46; Grubb 3rd"
                            2 => "K&#46; Hurley"
                            3 => "G&#46;M&#46; Glenn"
                            4 => "J&#46; Toro"
                            5 => "L&#46;S&#46; Schmidt"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1097/01.ju.0000154629.45832.30"
                      "Revista" => array:6 [
                        "tituloSerie" => "J Urol"
                        "fecha" => "2005"
                        "volumen" => "173"
                        "paginaInicial" => "1482"
                        "paginaFinal" => "1486"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15821464"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            19 => array:3 [
              "identificador" => "bib20"
              "etiqueta" => "20&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Understanding familial and non-familial renal cell cancer"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "D&#46; Bodmer"
                            1 => "W&#46; van den Hurk"
                            2 => "J&#46;J&#46; van Groningen"
                            3 => "M&#46;J&#46; Eleveld"
                            4 => "G&#46;J&#46; Martens"
                            5 => "M&#46;A&#46; Weterman"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Hum Mol Genet"
                        "fecha" => "2002"
                        "volumen" => "11"
                        "paginaInicial" => "2489"
                        "paginaFinal" => "2498"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12351585"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            20 => array:3 [
              "identificador" => "bib21"
              "etiqueta" => "21&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Renal tumors in the Birt-Hogg-Dub&#233; syndrome"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "C&#46;P&#46; Pavlovich"
                            1 => "M&#46;M&#46; Walther"
                            2 => "R&#46;A&#46; Eyler"
                            3 => "S&#46;M&#46; Hewitt"
                            4 => "B&#46; Zbar"
                            5 => "W&#46;M&#46; Linehan"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Am J Surg Pathol"
                        "fecha" => "2002"
                        "volumen" => "26"
                        "paginaInicial" => "1542"
                        "paginaFinal" => "1552"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12459621"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            21 => array:3 [
              "identificador" => "bib22"
              "etiqueta" => "22&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Letter&#58; hyfrecation and curettage as a treatment for fibrofolliculomas in Birt-Hogg-Dub&#233; syndrome"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "P&#46;B&#46; Farant"
                            1 => "R&#46; Emerson"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1111/j.1524-4725.2007.33270.x"
                      "Revista" => array:6 [
                        "tituloSerie" => "Dermatol Surg"
                        "fecha" => "2007"
                        "volumen" => "33"
                        "paginaInicial" => "1287"
                        "paginaFinal" => "1288"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/17903168"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            22 => array:3 [
              "identificador" => "bib23"
              "etiqueta" => "23&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Birt-Hogg-Dube syndrome&#58; treatment of cutaneous manifestations with laser skin resurfacing"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "C&#46;I&#46; Jacob"
                            1 => "J&#46;S&#46; Dover"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Arch Dermatol"
                        "fecha" => "2001"
                        "volumen" => "137"
                        "paginaInicial" => "98"
                        "paginaFinal" => "99"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11176677"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            23 => array:3 [
              "identificador" => "bib24"
              "etiqueta" => "24&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Tricodiscomas m&#250;ltiples familiares"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "M&#46;M&#46; Alsina"
                            1 => "J&#46; Ferrando"
                            2 => "J&#46;A&#46; Bomb&#237;"
                            3 => "A&#46; Pou"
                            4 => "H&#46; Torras"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Med Cutan Iber Lat Am"
                        "fecha" => "1990"
                        "volumen" => "18"
                        "paginaInicial" => "30"
                        "paginaFinal" => "34"
                      ]
                    ]
                  ]
                ]
              ]
            ]
          ]
        ]
      ]
    ]
  ]
  "idiomaDefecto" => "en"
  "url" => "/15782190/0000010000000003/v1_201304241451/S1578219009700496/v1_201304241451/en/main.assets"
  "Apartado" => array:4 [
    "identificador" => "6183"
    "tipo" => "SECCION"
    "en" => array:2 [
      "titulo" => "Case Reports"
      "idiomaDefecto" => true
    ]
    "idiomaDefecto" => "en"
  ]
  "PDF" => "https://static.elsevier.es/multimedia/15782190/0000010000000003/v1_201304241451/S1578219009700496/v1_201304241451/en/main.pdf?idApp=UINPBA000044&text.app=https://actasdermo.org/"
  "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219009700496?idApp=UINPBA000044"
]
Información del artículo
ISSN: 15782190
Idioma original: Inglés
Datos actualizados diariamente
año/Mes Html Pdf Total
2024 Noviembre 5 5 10
2024 Octubre 62 78 140
2024 Septiembre 67 54 121
2024 Agosto 121 81 202
2024 Julio 60 55 115
2024 Junio 57 80 137
2024 Mayo 49 53 102
2024 Abril 61 50 111
2024 Marzo 55 47 102
2024 Febrero 51 49 100
2024 Enero 51 50 101
2023 Diciembre 42 36 78
2023 Noviembre 44 52 96
2023 Octubre 45 37 82
2023 Septiembre 35 31 66
2023 Agosto 32 29 61
2023 Julio 38 80 118
2023 Junio 36 57 93
2023 Mayo 44 84 128
2023 Abril 26 51 77
2023 Marzo 20 37 57
2023 Febrero 21 34 55
2023 Enero 24 32 56
2022 Diciembre 21 51 72
2022 Noviembre 16 40 56
2022 Octubre 14 17 31
2022 Septiembre 12 29 41
2022 Agosto 19 35 54
2022 Julio 22 33 55
2022 Junio 18 28 46
2022 Mayo 24 51 75
2022 Abril 23 44 67
2022 Marzo 25 56 81
2022 Febrero 23 36 59
2022 Enero 27 59 86
2021 Diciembre 17 46 63
2021 Noviembre 31 47 78
2021 Octubre 35 61 96
2021 Septiembre 22 50 72
2021 Agosto 41 44 85
2021 Julio 32 54 86
2021 Junio 28 43 71
2021 Mayo 30 40 70
2021 Abril 76 43 119
2021 Marzo 105 43 148
2021 Febrero 62 37 99
2021 Enero 41 23 64
2020 Diciembre 27 16 43
2020 Noviembre 26 28 54
2020 Octubre 30 17 47
2020 Septiembre 16 14 30
2020 Agosto 34 33 67
2020 Julio 33 15 48
2020 Junio 16 46 62
2020 Mayo 22 36 58
2020 Abril 25 32 57
2020 Marzo 18 33 51
2020 Febrero 1 14 15
2020 Enero 0 14 14
2019 Diciembre 0 15 15
2019 Noviembre 0 5 5
2019 Octubre 0 12 12
2019 Septiembre 0 25 25
2019 Agosto 0 3 3
2019 Julio 0 10 10
2019 Junio 0 7 7
2019 Mayo 0 50 50
2019 Abril 0 30 30
2019 Marzo 0 5 5
2019 Febrero 0 8 8
2019 Enero 0 2 2
2018 Diciembre 0 7 7
2018 Abril 0 1 1
2018 Marzo 1 1 2
2018 Febrero 7 3 10
2018 Enero 11 6 17
2017 Diciembre 13 9 22
2017 Noviembre 11 5 16
2017 Octubre 10 7 17
2017 Septiembre 7 6 13
2017 Agosto 12 7 19
2017 Julio 7 3 10
2017 Junio 22 23 45
2017 Mayo 14 5 19
2017 Abril 14 15 29
2017 Marzo 15 8 23
2017 Febrero 9 7 16
2017 Enero 13 3 16
2016 Diciembre 22 8 30
2016 Noviembre 15 5 20
2016 Octubre 18 15 33
2016 Septiembre 27 7 34
2016 Agosto 27 5 32
2016 Julio 17 9 26
2016 Junio 16 10 26
2016 Mayo 7 3 10
2016 Abril 6 6 12
2016 Marzo 8 3 11
2016 Febrero 11 1 12
2016 Enero 2 1 3
2015 Diciembre 8 0 8
2015 Noviembre 13 1 14
2015 Octubre 10 2 12
2015 Septiembre 7 2 9
2015 Agosto 17 4 21
2015 Julio 40 7 47
2015 Junio 39 4 43
2015 Mayo 79 10 89
2015 Abril 40 2 42
2015 Marzo 40 9 49
2015 Febrero 31 5 36
2015 Enero 30 9 39
2014 Diciembre 25 4 29
2014 Noviembre 26 17 43
2014 Octubre 38 18 56
2014 Septiembre 39 15 54
2014 Agosto 30 19 49
2014 Julio 47 21 68
2014 Junio 46 13 59
2014 Mayo 46 9 55
2014 Abril 55 8 63
2014 Marzo 79 15 94
2014 Febrero 40 16 56
2014 Enero 48 16 64
2013 Diciembre 46 10 56
2013 Noviembre 27 20 47
2013 Octubre 33 10 43
2013 Septiembre 31 15 46
2013 Agosto 27 11 38
2013 Julio 30 16 46
2013 Junio 31 10 41
2013 Mayo 20 10 30
2013 Abril 27 16 43
2013 Marzo 26 16 42
2013 Febrero 31 10 41
2013 Enero 12 4 16
Mostrar todo

Siga este enlace para acceder al texto completo del artículo

Idiomas
Actas Dermo-Sifiliográficas
es en

¿Es usted profesional sanitario apto para prescribir o dispensar medicamentos?

Are you a health professional able to prescribe or dispense drugs?