Update of the Topical Treatment of Psoriasis | Actas Dermo-Sifiliográficas

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Topical corticosteroids and vitamin D analogs are the drugs of choice during the induction phase, and vitamin D analogs continue to be drugs of choice for maintenance therapy. Tazarotene and dithranol are suitable options in patients with certain, specific characteristics. The calcineurin inhibitors can be considered to be second-line treatment for psoriasis of the face and flexures. The efficacy and safety of the fixed-dose combination of betamethasone and calcipotriol in the induction phase is greater than that of either drug alone. The combination of corticosteroids with salicylic acid achieves better results than corticosteroids in monotherapy. None of the drugs evaluated stands out over the others in all clinical situations, and their use must therefore be individualized in each patient and adjusted according to the course of the disease." ] "es" => array:2 [ "titulo" => "Resumen" "resumen" => "La terapia tópica sigue representando un pilar fundamental y de actualidad en el manejo de la psoriasis. Los corticoides tópicos y los análogos de la vitamina D son los principios activos de elección durante la fase de inducción, mientras que estos últimos se mantienen como alternativa de elección en el mantenimiento. El tazaroteno y el ditranol resultan alternativas adecuadas en pacientes con determinadas características. Los inhibidores de la calcineurina pueden considerarse tratamientos de segunda línea en la psoriasis de la cara y las flexuras. La eficacia y la seguridad en la fase de inducción de la combinación en dosis fija de betametasona y calcipotriol es superior a la obtenida por ambos principios activos por separado. La combinación de corticoides con ácido salicílico aporta ventajas con respecto a los corticoides en monoterapia. Ninguno de los principios activos evaluados presenta ventajas sobre el resto en todas las situaciones clínicas, por lo que su empleo debe individualizarse para cada paciente y para cada momento evolutivo de la dermatosis." ] ] "bibliografia" => array:2 [ "titulo" => "References" "seccion" => array:1 [ 0 => array:1 [ "bibliografiaReferencia" => array:62 [ 0 => array:3 [ "identificador" => "bib1" "etiqueta" => "1." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Prevalence of psoriasis in Spain (Epiderma Project: phase I)" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "C. Ferrándiz" 1 => "X. Bordas" 2 => "V. García-Patos" 3 => "S. Puig" 4 => "R. Pujol" 5 => "A. 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Estadísticas

Consensus statement

Update of the Topical Treatment of Psoriasis

Revisión Actualizada del Tratamiento Tópico de la Psoriasis

J.M. Carrascosaa,

Autor para correspondencia

jmcarrascosac@hotmail.com

Correspondence: Servicio de Dermatología, Hospital Universitario Germans Trias i Pujol, 08916 Badalona, Barcelona, Spain.

, F. Vanaclocha,b, L. Borregoc, E. Fernández-Lópezd, A. Fuertese, L. Rodríguez-Fernández-Freiref, A. Zulaicag, A. Tuneuh, G. Caballéi, E. Coloméi, X. Bordasj, J.M. Hernanzk, C. Brufaul, E. Herreram

a Servicio de Dermatología, Hospital Universitario Germans Trias i Pujol, Badalona, Barcelona

b Servicio de Dermatología, Hospital 12 de Octubre, Madrid

c Hospital Universitario Insular de Gran Canaria, Las Palmas, Valencia

d Servicio de Dermatología, Hospital Universitario de Salamanca, Valencia

e Servicio de Dermatología, Hospital Universitario Dr. Peset, Valencia

f Servicio de Dermatología, Hospital Universitario de Sevilla, Pontevedra

g Servicio de Dermatología, Complejo Hospitalario Universitario de Vigo, Vigo, Pontevedra

h Hospital Donostia, San Sebastian

i LEO Pharma, Barcelona

j Ciutat Universitaria de Bellvitge, Barcelona

k Sección de Dermatología, Hospital Infanta Leonor, Madrid

l Servicio de Dermatología, Hospital General Universitario Reina Sofía, Murcia

m Servicio de Dermatología, Hospital Clínico, Málaga, Spain

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Información del artículo

ISSN: 15782190
Idioma original: Inglés

DOI:10.1016/S1578-2190(09)70044-7

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