Correspondence: Servicio de Dermatología, Hospital del Mar, c/ Passeig Maritím, 25-29, 08003 Barcelona.
se ha leído el artículo
array:23 [ "pii" => "S1578219008703433" "issn" => "15782190" "doi" => "10.1016/S1578-2190(08)70343-3" "estado" => "S300" "fechaPublicacion" => "2008-11-01" "aid" => "70343" "copyright" => "Academia Española de Dermatología y Venereología and Elsevier España, S.L." "copyrightAnyo" => "2008" "documento" => "article" "crossmark" => 0 "subdocumento" => "rev" "cita" => "Actas Dermosifiliogr. 2008;99:671-82" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 5506 "formatos" => array:3 [ "EPUB" => 32 "HTML" => 1806 "PDF" => 3668 ] ] "itemSiguiente" => array:18 [ "pii" => "S1578219008703445" "issn" => "15782190" "doi" => "10.1016/S1578-2190(08)70344-5" "estado" => "S300" "fechaPublicacion" => "2008-11-01" "aid" => "70344" "copyright" => "Academia Española de Dermatología y Venereología and Elsevier España, S.L." "documento" => "article" "crossmark" => 0 "subdocumento" => "fla" "cita" => "Actas Dermosifiliogr. 2008;99:683-9" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 6963 "formatos" => array:3 [ "EPUB" => 34 "HTML" => 1544 "PDF" => 5385 ] ] "en" => array:11 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Practical dermatology</span>" "titulo" => "Antibiotic Prophylaxis in Dermatologic Surgery" "tienePdf" => "en" "tieneTextoCompleto" => 0 "tieneResumen" => array:2 [ 0 => "en" 1 => "es" ] "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "683" "paginaFinal" => "689" ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Profilaxis Antibiótica en Cirugía Dermatológica" ] ] "contieneResumen" => array:2 [ "en" => true "es" => true ] "contienePdf" => array:1 [ "en" => true ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "M. Yuste, A. Romo, P. de Unamuno" "autores" => array:3 [ 0 => array:2 [ "nombre" => "M." "apellidos" => "Yuste" ] 1 => array:2 [ "nombre" => "A." "apellidos" => "Romo" ] 2 => array:2 [ "nombre" => "P." "apellidos" => "de Unamuno" ] ] ] ] ] "idiomaDefecto" => "en" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219008703445?idApp=UINPBA000044" "url" => "/15782190/0000009900000009/v1_201304241441/S1578219008703445/v1_201304241441/en/main.assets" ] "itemAnterior" => array:18 [ "pii" => "S1578219008703421" "issn" => "15782190" "doi" => "10.1016/S1578-2190(08)70342-1" "estado" => "S300" "fechaPublicacion" => "2008-11-01" "aid" => "70342" "copyright" => "Academia Española de Dermatología y Venereología and Elsevier España, S.L." "documento" => "article" "crossmark" => 0 "subdocumento" => "fla" "cita" => "Actas Dermosifiliogr. 2008;99:669-70" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 2022 "formatos" => array:3 [ "EPUB" => 38 "HTML" => 1307 "PDF" => 677 ] ] "en" => array:8 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Opinion article</span>" "titulo" => "Surgical Training of Dermatologists" "tienePdf" => "en" "tieneTextoCompleto" => 0 "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "669" "paginaFinal" => "670" ] ] "contienePdf" => array:1 [ "en" => true ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "S. Serrano" "autores" => array:1 [ 0 => array:2 [ "nombre" => "S." "apellidos" => "Serrano" ] ] ] ] ] "idiomaDefecto" => "en" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219008703421?idApp=UINPBA000044" "url" => "/15782190/0000009900000009/v1_201304241441/S1578219008703421/v1_201304241441/en/main.assets" ] "en" => array:14 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Review article</span>" "titulo" => "Xerosis: a Dysfunction of the Epidermal Barrier" "tieneTextoCompleto" => 0 "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "671" "paginaFinal" => "682" ] ] "autores" => array:1 [ 0 => array:4 [ "autoresLista" => "D. Barco, A. Giménez-Arnau" "autores" => array:2 [ 0 => array:3 [ "nombre" => "D." "apellidos" => "Barco" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff1" ] ] ] 1 => array:4 [ "nombre" => "A." "apellidos" => "Giménez-Arnau" "email" => array:1 [ 0 => "agimenez@imas.imim.es" ] "referencia" => array:2 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff2" ] 1 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">¿</span>" "identificador" => "cor1" ] ] ] ] "afiliaciones" => array:2 [ 0 => array:3 [ "entidad" => "Servicio de Dermatología, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain" "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff1" ] 1 => array:3 [ "entidad" => "Departamento de Dermatología, Hospital del Mar-IMIM, Barcelona Spain" "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff2" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor1" "etiqueta" => "⁎" "correspondencia" => "Correspondence: Servicio de Dermatología, Hospital del Mar, c/ Passeig Maritím, 25-29, 08003 Barcelona." ] ] ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Xerosis: una Disfunción de la Barrera Epidérmica" ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaAceptado" => "2008-02-27" "PalabrasClave" => array:2 [ "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Key words" "identificador" => "xpalclavsec84294" "palabras" => array:5 [ 0 => "xerosis" 1 => "dry skin" 2 => "stratum corneum" 3 => "ceramides" 4 => "lipids" ] ] ] "es" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palabras clave" "identificador" => "xpalclavsec84293" "palabras" => array:5 [ 0 => "xerosis" 1 => "piel seca" 2 => "estrato córneo" 3 => "ceramidas" 4 => "lípidos" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "en" => array:2 [ "titulo" => "Abstract" "resumen" => "<p class="elsevierStyleSimplePara elsevierViewall">Xerosis or dry skin is a common skin disorder among the general population. It is characterized clinically by rough, scaly, and often itchy skin. This disorder is present in the course of some dermatoses such as atopic dermatitis, although it can also occur in healthy individuals if a combination of certain etiologic factors is present. It is characterized pathophysiologically by a disrupted stratum corneum, dehydration, and impaired keratinocyte differentiation. Treatment of xerosis should seek to restore physiologic lipids in the epidermis and provide substances that facilitate epidermal differentiation.</p>" ] "es" => array:2 [ "titulo" => "Resumen" "resumen" => "<p class="elsevierStyleSimplePara elsevierViewall">La xerosis o piel seca es un trastorno cutáneo de alta prevalencia en la población general que se caracteriza clínicamente por una piel áspera, descamativa y habitualmente pruriginosa. Ciertas dermatosis como la dermatitis atópica cursan con este trastorno, aunque puede presentarse en individuos sanos si coinciden varios factores etiológicos. Fisiopatológicamente consiste en la modificación estructural del estrato córneo, su contenido en agua y un defecto en la diferenciación queratinocitaria. El tratamiento de la xerosis debiera buscar la recomposición de los lípidos fisiológicos de la epidermis y el aporte de sustancias que faciliten la diferenciación epidérmica.</p>" ] ] "bibliografia" => array:2 [ "titulo" => "References" "seccion" => array:1 [ 0 => array:1 [ "bibliografiaReferencia" => array:30 [ 0 => array:3 [ "identificador" => "bib1" "etiqueta" => "1." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Eczema, ichthyosis, psoriasis: conditions of cornification" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "S.R. Burdette-Taylor" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Ostomy Wound Manage" "fecha" => "1995" "volumen" => "41" "paginaInicial" => "36" "paginaFinal" => "38" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/7546119" "web" => "Medline" ] ] ] ] ] ] ] ] 1 => array:3 [ "identificador" => "bib2" "etiqueta" => "2." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The management of dry skin with topical emollients–recent perspectives" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "E. Proksch" 1 => "J.M. Lachapelle" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1111/j.1610-0387.2005.05068.x" "Revista" => array:6 [ "tituloSerie" => "J Dtsch Dermatol Ges" "fecha" => "2005" "volumen" => "3" "paginaInicial" => "768" "paginaFinal" => "774" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16194154" "web" => "Medline" ] ] ] ] ] ] ] ] 2 => array:3 [ "identificador" => "bib3" "etiqueta" => "3." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Cholesterol synthesis is required for cutaneous barrier function in mice" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "K.R. Feingold" 1 => "M. Mao-Quian" 2 => "G.K. Menon" 3 => "S.S. Cho" 4 => "B.E. Brown" 5 => "P.M. Elias" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1172/JCI114899" "Revista" => array:6 [ "tituloSerie" => "J Clin Invest" "fecha" => "1990" "volumen" => "86" "paginaInicial" => "1738" "paginaFinal" => "1745" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/2243142" "web" => "Medline" ] ] ] ] ] ] ] ] 3 => array:3 [ "identificador" => "bib4" "etiqueta" => "4." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Lipid content and lipid type as determinants of the epidermal permeability barrier" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "G. Grubauer" 1 => "K.R. Feingold" 2 => "R.M. Harris" 3 => "P.M. Elias" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "J Lipid Res" "fecha" => "1989" "volumen" => "30" "paginaInicial" => "89" "paginaFinal" => "96" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/2918253" "web" => "Medline" ] ] ] ] ] ] ] ] 4 => array:3 [ "identificador" => "bib5" "etiqueta" => "5." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Stratum corneum defensive functions: an integrated view" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "P.M. Elias" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1111/j.0022-202X.2005.23668.x" "Revista" => array:6 [ "tituloSerie" => "J Invest Dermatol" "fecha" => "2005" "volumen" => "125" "paginaInicial" => "183" "paginaFinal" => "200" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16098026" "web" => "Medline" ] ] ] ] ] ] ] ] 5 => array:3 [ "identificador" => "bib6" "etiqueta" => "6." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Relationship between NMF (lactate and potassium) content and the physical properties of the stratum corneum in healthy subjects" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "N. Nakagawa" 1 => "S. Sakai" 2 => "M. Matsumoto" 3 => "K. Yamada" 4 => "M. Nagano" 5 => "T. Yuki" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1111/j.0022-202X.2004.22317.x" "Revista" => array:6 [ "tituloSerie" => "J Invest Dermatol" "fecha" => "2004" "volumen" => "122" "paginaInicial" => "755" "paginaFinal" => "763" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15086563" "web" => "Medline" ] ] ] ] ] ] ] ] 6 => array:3 [ "identificador" => "bib7" "etiqueta" => "7." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "How to choose a suitable emollient" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "C. Clark" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Pharm J" "fecha" => "2004" "volumen" => "273" "paginaInicial" => "351" "paginaFinal" => "353" ] ] ] ] ] ] 7 => array:3 [ "identificador" => "bib8" "etiqueta" => "8." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Stratum corneum moisturization at the molecular level: an update in relation to the dry skin cycle" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "A.V. Rawlings" 1 => "P.J. Matts" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1111/j.1523-1747.2005.23726.x" "Revista" => array:6 [ "tituloSerie" => "J Invest Dermatol" "fecha" => "2005" "volumen" => "124" "paginaInicial" => "1099" "paginaFinal" => "1110" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15955083" "web" => "Medline" ] ] ] ] ] ] ] ] 8 => array:3 [ "identificador" => "bib9" "etiqueta" => "9." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Low humidity and microtrauma" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "R.J.G. Rycroft" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Am J Ind Med" "fecha" => "1985" "volumen" => "8" "paginaInicial" => "371" "paginaFinal" => "373" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/4073035" "web" => "Medline" ] ] ] ] ] ] ] ] 9 => array:3 [ "identificador" => "bib10" "etiqueta" => "10." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Ceramide and cholesterol composition of the skin of patients with atopic dermatitis" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "A. Di Nardo" 1 => "P. Werz" 2 => "A. Giannetti" 3 => "S. Deidenari" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Acta Dermatol Venereol" "fecha" => "1998" "volumen" => "78" "paginaInicial" => "27" "paginaFinal" => "30" ] ] ] ] ] ] 10 => array:3 [ "identificador" => "bib11" "etiqueta" => "11." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Filaggrin mutations in children with severe atopic dermatitis" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "N. Morar" 1 => "W.O. Cookson" 2 => "J.I. Harper" 3 => "M.F. Moffatt" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1038/sj.jid.5700739" "Revista" => array:6 [ "tituloSerie" => "J Invest Dermatol" "fecha" => "2007" "volumen" => "127" "paginaInicial" => "1667" "paginaFinal" => "1672" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/17301831" "web" => "Medline" ] ] ] ] ] ] ] ] 11 => array:3 [ "identificador" => "bib12" "etiqueta" => "12." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The content of free amino acids in the stratum corneum is increased in senile xerosis" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "M. Takahashi" 1 => "T. Tezuka" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1007/s00403-003-0448-x" "Revista" => array:6 [ "tituloSerie" => "Arch Dermatol Res" "fecha" => "2004" "volumen" => "295" "paginaInicial" => "448" "paginaFinal" => "452" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/14762669" "web" => "Medline" ] ] ] ] ] ] ] ] 12 => array:3 [ "identificador" => "bib13" "etiqueta" => "13." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Changes in environmental humidity affect the water-holding property of the stratum corneum and its free amino acid content, and the expression of the filaggrin in the epidermis of hairless mice" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "C. Katagiri" 1 => "J. Sato" 2 => "J. Nomura" 3 => "M. Denda" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "J Dermatol Sci" "fecha" => "2003" "volumen" => "31" "paginaInicial" => "29" "paginaFinal" => "35" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12615361" "web" => "Medline" ] ] ] ] ] ] ] ] 13 => array:3 [ "identificador" => "bib14" "etiqueta" => "14." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Signaling networks in barrier homeostasis: the mystery widens" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "P.M. Elias" 1 => "J.C. Ansel" 2 => "L.D. Woods" 3 => "K.R. Feingold" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Arch Dermatol" "fecha" => "1996" "volumen" => "132" "paginaInicial" => "1505" "paginaFinal" => "1506" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8961883" "web" => "Medline" ] ] ] ] ] ] ] ] 14 => array:3 [ "identificador" => "bib15" "etiqueta" => "15." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Epidermal pathogenesis of inflammatory dermatoses" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "P.M. Elias" 1 => "L.D. Woods" 2 => "K.R. Feingold" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Am J Contact Dermat" "fecha" => "1999" "volumen" => "10" "paginaInicial" => "119" "paginaFinal" => "126" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10444104" "web" => "Medline" ] ] ] ] ] ] ] ] 15 => array:3 [ "identificador" => "bib16" "etiqueta" => "16." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Low humidity occupational dermatoses" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "P.J.G. Rycroft" 1 => "W.D.L. Smith" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Contact Dermatitis" "fecha" => "1980" "volumen" => "6" "paginaInicial" => "488" "paginaFinal" => "492" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/6452248" "web" => "Medline" ] ] ] ] ] ] ] ] 16 => array:3 [ "identificador" => "bib17" "etiqueta" => "17." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Seasonal variation of skin resistance to irritants" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "T. Agner" 1 => "J. Serup" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Br J Dermatol" "fecha" => "1989" "volumen" => "121" "paginaInicial" => "323" "paginaFinal" => "328" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/2803958" "web" => "Medline" ] ] ] ] ] ] ] ] 17 => array:3 [ "identificador" => "bib18" "etiqueta" => "18." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Effects of xerosis and ageing on epidermal proliferation and differentiation" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "M. Engelke" 1 => "J.M. Jensen" 2 => "S. Ekanayake-Mudiyanselage" 3 => "E. Proksch" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Br J Dermatol" "fecha" => "1997" "volumen" => "137" "paginaInicial" => "219" "paginaFinal" => "225" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9292070" "web" => "Medline" ] ] ] ] ] ] ] ] 18 => array:3 [ "identificador" => "bib19" "etiqueta" => "19." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "New perspectives on epidermal barrier dysfunction in atopic dermatitis: geneenvironment interactions" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "M.J. Cork" 1 => "D.A. Robinson" 2 => "Y. Vasilopoulos" 3 => "A. Ferguson" 4 => "M. Moustafa" 5 => "A. MacGowan" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/j.jaci.2006.04.042" "Revista" => array:6 [ "tituloSerie" => "J Allergy Clin Immunol" "fecha" => "2006" "volumen" => "118" "paginaInicial" => "3" "paginaFinal" => "21" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16815133" "web" => "Medline" ] ] ] ] ] ] ] ] 19 => array:3 [ "identificador" => "bib20" "etiqueta" => "20." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Transepidermal water loss in dry and clinically normal skin in patients with atopic dermatitis" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "Y. Werner" 1 => "M. Lindberg" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:7 [ "tituloSerie" => "Acta Derm Venereol" "fecha" => "1985" "volumen" => "65" "paginaInicial" => "102" "paginaFinal" => "105" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/2408409" "web" => "Medline" ] ] "itemHostRev" => array:3 [ "pii" => "S0140673605678890" "estado" => "S300" "issn" => "01406736" ] ] ] ] ] ] ] 20 => array:3 [ "identificador" => "bib21" "etiqueta" => "21." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Evaluation of the hydration and water binding capacity in atopic skin and so-called dry skin" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "P. Thune" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Acta Derm Venereol" "fecha" => "1989" "volumen" => "144" "numero" => "Suppl" "paginaInicial" => "133" "paginaFinal" => "135" ] ] ] ] ] ] 21 => array:3 [ "identificador" => "bib22" "etiqueta" => "22." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "X-linked ichthyosis due to steroid sulphatase deficiency" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "L.J. Shapiro" 1 => "R Weiss" 2 => "Webster." 3 => "J.T. Frances" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Lancet" "fecha" => "1978" "volumen" => "1" "paginaInicial" => "70" "paginaFinal" => "72" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/6140424" "web" => "Medline" ] ] ] ] ] ] ] ] 22 => array:3 [ "identificador" => "bib23" "etiqueta" => "23." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Cholesterol sulphate inhibits proteases that are involved in desquamation of stratum corneum" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "J. Sato" 1 => "M. Denda" 2 => "J. Nakinishi" 3 => "J. Nomura" 4 => "J. Koyama" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1046/j.1523-1747.1998.00244.x" "Revista" => array:6 [ "tituloSerie" => "J Invest Dermatol" "fecha" => "1998" "volumen" => "111" "paginaInicial" => "189" "paginaFinal" => "194" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9699715" "web" => "Medline" ] ] ] ] ] ] ] ] 23 => array:3 [ "identificador" => "bib24" "etiqueta" => "24." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Dermatitis de manos" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "C. Ramírez" 1 => "S.E. Jacob" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Actas Dermosifiliogr" "fecha" => "2006" "volumen" => "97" "paginaInicial" => "363" "paginaFinal" => "373" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16956515" "web" => "Medline" ] ] ] ] ] ] ] ] 24 => array:3 [ "identificador" => "bib25" "etiqueta" => "25." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Ceramide-dominant barrier repair lipids alleviate childhood atopic dermatitis: changes in barrier function provide a sensitive indicator of disease activity" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "S.L. Chamlin" 1 => "J. Kao" 2 => "I.J. Freiden" 3 => "M.Y. Sheu" 4 => "A.J. Fowler" 5 => "J.W. Fluhr" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "J Am Acad Dermatol" "fecha" => "2002" "volumen" => "47" "paginaInicial" => "198" "paginaFinal" => "208" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12140465" "web" => "Medline" ] ] ] ] ] ] ] ] 25 => array:3 [ "identificador" => "bib26" "etiqueta" => "26." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Glycerol replacement corrects defective skin hydration, elasticity and barrier function in aquaporin-3-deficient mice" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "M. Hara" 1 => "A.S. Verkman" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1073/pnas.1230416100" "Revista" => array:6 [ "tituloSerie" => "PNAS" "fecha" => "2003" "volumen" => "100" "paginaInicial" => "7360" "paginaFinal" => "7365" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12771381" "web" => "Medline" ] ] ] ] ] ] ] ] 26 => array:3 [ "identificador" => "bib27" "etiqueta" => "27." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Etude in vitro du pouvoir antiprurigineux du glycocolle: effet sur la dégranulation des mastocytes" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "M. Paubert-Braquet" 1 => "G. Lefrançois" 2 => "S. Picquot" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Thérapeutique" "fecha" => "1992" "volumen" => "95" "paginaInicial" => "2" "paginaFinal" => "3" ] ] ] ] ] ] 27 => array:3 [ "identificador" => "bib28" "etiqueta" => "28." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Studies on wound healing: effects of calcium pantothenate on the migration, proliferation and protein synthesis of human dermal fibroblasts in culture" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "B.I. Weimann" 1 => "D. Hermann" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1024/0300-9831.69.2.113" "Revista" => array:6 [ "tituloSerie" => "Int J Vitam Nutr Res" "fecha" => "1999" "volumen" => "69" "paginaInicial" => "113" "paginaFinal" => "119" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10218148" "web" => "Medline" ] ] ] ] ] ] ] ] 28 => array:3 [ "identificador" => "bib29" "etiqueta" => "29." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Effects of pantothenic acid on fibroblastic cell cultures" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "B. Lacroix" 1 => "E. Didier" 2 => "J.F. Grenier" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Res Exp Med" "fecha" => "1988" "volumen" => "188" "paginaInicial" => "391" "paginaFinal" => "396" ] ] ] ] ] ] 29 => array:3 [ "identificador" => "bib30" "etiqueta" => "30." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Effect of bepanthen ointment on the graft-donor site wound-healing model: double-blind biometrological and clinical study, with assessment by the patient versus the vehicle" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "P. Girard" 1 => "A. Beraud" 2 => "C. Goujon" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Nouv Dermatol" "fecha" => "1998" "volumen" => "17" "paginaInicial" => "559" "paginaFinal" => "570" ] ] ] ] ] ] ] ] ] ] ] "idiomaDefecto" => "en" "url" => "/15782190/0000009900000009/v1_201304241441/S1578219008703433/v1_201304241441/en/main.assets" "Apartado" => array:4 [ "identificador" => "6224" "tipo" => "SECCION" "en" => array:2 [ "titulo" => "Review article" "idiomaDefecto" => true ] "idiomaDefecto" => "en" ] "PDF" => "https://static.elsevier.es/multimedia/15782190/0000009900000009/v1_201304241441/S1578219008703433/v1_201304241441/en/main.pdf?idApp=UINPBA000044&text.app=https://actasdermo.org/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219008703433?idApp=UINPBA000044" ]
año/Mes | Html | Total | |
---|---|---|---|
2024 Noviembre | 5 | 6 | 11 |
2024 Octubre | 74 | 73 | 147 |
2024 Septiembre | 73 | 56 | 129 |
2024 Agosto | 95 | 99 | 194 |
2024 Julio | 79 | 80 | 159 |
2024 Junio | 69 | 84 | 153 |
2024 Mayo | 65 | 52 | 117 |
2024 Abril | 60 | 32 | 92 |
2024 Marzo | 82 | 55 | 137 |
2024 Febrero | 56 | 48 | 104 |
2024 Enero | 65 | 73 | 138 |
2023 Diciembre | 68 | 53 | 121 |
2023 Noviembre | 64 | 47 | 111 |
2023 Octubre | 60 | 56 | 116 |
2023 Septiembre | 59 | 49 | 108 |
2023 Agosto | 42 | 29 | 71 |
2023 Julio | 79 | 75 | 154 |
2023 Junio | 63 | 27 | 90 |
2023 Mayo | 44 | 33 | 77 |
2023 Abril | 44 | 28 | 72 |
2023 Marzo | 30 | 45 | 75 |
2023 Febrero | 24 | 41 | 65 |
2023 Enero | 31 | 44 | 75 |
2022 Diciembre | 30 | 50 | 80 |
2022 Noviembre | 19 | 36 | 55 |
2022 Octubre | 13 | 40 | 53 |
2022 Septiembre | 14 | 57 | 71 |
2022 Agosto | 16 | 49 | 65 |
2022 Julio | 15 | 88 | 103 |
2022 Junio | 37 | 46 | 83 |
2022 Mayo | 56 | 61 | 117 |
2022 Abril | 62 | 63 | 125 |
2022 Marzo | 37 | 51 | 88 |
2022 Febrero | 54 | 30 | 84 |
2022 Enero | 31 | 49 | 80 |
2021 Diciembre | 38 | 69 | 107 |
2021 Noviembre | 49 | 58 | 107 |
2021 Octubre | 46 | 55 | 101 |
2021 Septiembre | 38 | 50 | 88 |
2021 Agosto | 39 | 47 | 86 |
2021 Julio | 35 | 42 | 77 |
2021 Junio | 37 | 40 | 77 |
2021 Mayo | 35 | 37 | 72 |
2021 Abril | 44 | 80 | 124 |
2021 Marzo | 85 | 73 | 158 |
2021 Febrero | 86 | 56 | 142 |
2021 Enero | 40 | 42 | 82 |
2020 Diciembre | 62 | 38 | 100 |
2020 Noviembre | 29 | 29 | 58 |
2020 Octubre | 46 | 20 | 66 |
2020 Septiembre | 39 | 17 | 56 |
2020 Agosto | 32 | 78 | 110 |
2020 Julio | 37 | 35 | 72 |
2020 Junio | 31 | 28 | 59 |
2020 Mayo | 25 | 35 | 60 |
2020 Abril | 26 | 31 | 57 |
2020 Marzo | 19 | 32 | 51 |
2020 Febrero | 3 | 23 | 26 |
2020 Enero | 3 | 11 | 14 |
2019 Diciembre | 0 | 32 | 32 |
2019 Noviembre | 0 | 32 | 32 |
2019 Octubre | 0 | 37 | 37 |
2019 Septiembre | 0 | 35 | 35 |
2019 Agosto | 0 | 17 | 17 |
2019 Julio | 0 | 28 | 28 |
2019 Junio | 0 | 21 | 21 |
2019 Mayo | 1 | 129 | 130 |
2019 Abril | 0 | 79 | 79 |
2019 Marzo | 0 | 18 | 18 |
2019 Febrero | 0 | 32 | 32 |
2019 Enero | 1 | 26 | 27 |
2018 Diciembre | 1 | 10 | 11 |
2018 Noviembre | 0 | 3 | 3 |
2018 Octubre | 0 | 1 | 1 |
2018 Septiembre | 1 | 13 | 14 |
2018 Agosto | 0 | 27 | 27 |
2018 Julio | 0 | 21 | 21 |
2018 Junio | 0 | 26 | 26 |
2018 Mayo | 0 | 10 | 10 |
2018 Abril | 0 | 23 | 23 |
2018 Marzo | 0 | 40 | 40 |
2018 Febrero | 16 | 46 | 62 |
2018 Enero | 14 | 29 | 43 |
2017 Diciembre | 21 | 42 | 63 |
2017 Noviembre | 25 | 67 | 92 |
2017 Octubre | 18 | 53 | 71 |
2017 Septiembre | 21 | 51 | 72 |
2017 Agosto | 27 | 44 | 71 |
2017 Julio | 20 | 63 | 83 |
2017 Junio | 33 | 69 | 102 |
2017 Mayo | 35 | 48 | 83 |
2017 Abril | 35 | 81 | 116 |
2017 Marzo | 45 | 90 | 135 |
2017 Febrero | 24 | 96 | 120 |
2017 Enero | 31 | 98 | 129 |
2016 Diciembre | 31 | 55 | 86 |
2016 Noviembre | 27 | 76 | 103 |
2016 Octubre | 29 | 122 | 151 |
2016 Septiembre | 42 | 90 | 132 |
2016 Agosto | 56 | 48 | 104 |
2016 Julio | 35 | 37 | 72 |
2016 Junio | 12 | 35 | 47 |
2016 Mayo | 5 | 24 | 29 |
2016 Abril | 6 | 17 | 23 |
2016 Marzo | 3 | 1 | 4 |
2016 Febrero | 5 | 13 | 18 |
2016 Enero | 6 | 13 | 19 |
2015 Diciembre | 13 | 15 | 28 |
2015 Noviembre | 19 | 17 | 36 |
2015 Octubre | 6 | 14 | 20 |
2015 Septiembre | 7 | 1 | 8 |
2015 Agosto | 13 | 10 | 23 |
2015 Julio | 35 | 65 | 100 |
2015 Junio | 42 | 42 | 84 |
2015 Mayo | 63 | 45 | 108 |
2015 Abril | 45 | 49 | 94 |
2015 Marzo | 39 | 42 | 81 |
2015 Febrero | 30 | 48 | 78 |
2015 Enero | 37 | 54 | 91 |
2014 Diciembre | 28 | 40 | 68 |
2014 Noviembre | 30 | 35 | 65 |
2014 Octubre | 31 | 38 | 69 |
2014 Septiembre | 29 | 32 | 61 |
2014 Agosto | 34 | 31 | 65 |
2014 Julio | 48 | 33 | 81 |
2014 Junio | 49 | 16 | 65 |
2014 Mayo | 38 | 18 | 56 |
2014 Abril | 35 | 13 | 48 |
2014 Marzo | 45 | 55 | 100 |
2014 Febrero | 40 | 49 | 89 |
2014 Enero | 50 | 44 | 94 |
2013 Diciembre | 38 | 39 | 77 |
2013 Noviembre | 34 | 67 | 101 |
2013 Octubre | 37 | 48 | 85 |
2013 Septiembre | 34 | 52 | 86 |
2013 Agosto | 33 | 88 | 121 |
2013 Julio | 20 | 106 | 126 |
2013 Junio | 19 | 102 | 121 |
2013 Mayo | 54 | 81 | 135 |
2013 Abril | 22 | 78 | 100 |
2013 Marzo | 28 | 73 | 101 |
2013 Febrero | 32 | 27 | 59 |
2013 Enero | 20 | 10 | 30 |