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Correlation Between Clinical, Dermatoscopic, and Histopathologic Variables in Atypical Melanocytic Nevi
Estudio de Correlación Clínica, Dermatoscópica e Histopatológica de Nevus Melanocíticos Atípicos
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Belinchón, J.M. Ramos" "autores" => array:2 [ 0 => array:2 [ "nombre" => "I." "apellidos" => "Belinchón" ] 1 => array:2 [ "nombre" => "J.M." "apellidos" => "Ramos" ] ] ] ] ] "idiomaDefecto" => "en" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219008702701?idApp=UINPBA000044" "url" => "/15782190/0000009900000005/v1_201304241433/S1578219008702701/v1_201304241433/en/main.assets" ] "en" => array:14 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Original articles</span>" "titulo" => "Correlation Between Clinical, Dermatoscopic, and Histopathologic Variables in Atypical Melanocytic Nevi" "tieneTextoCompleto" => 0 "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "380" "paginaFinal" => "389" ] ] "autores" => array:1 [ 0 => array:4 [ "autoresLista" => "A.M. Morales-Callaghan, J. Castrodeza-Sanz, G. Martínez-García, I. Peral-Martínez, A. Miranda-Romero" "autores" => array:5 [ 0 => array:4 [ "nombre" => "A.M." "apellidos" => "Morales-Callaghan" "email" => array:1 [ 0 => "acallaghan@aedv.es" ] "referencia" => array:2 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff1" ] 1 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">¿</span>" "identificador" => "cor1" ] ] ] 1 => array:3 [ "nombre" => "J." "apellidos" => "Castrodeza-Sanz" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff2" ] ] ] 2 => array:3 [ "nombre" => "G." "apellidos" => "Martínez-García" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">c</span>" "identificador" => "aff3" ] ] ] 3 => array:3 [ "nombre" => "I." "apellidos" => "Peral-Martínez" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">c</span>" "identificador" => "aff3" ] ] ] 4 => array:3 [ "nombre" => "A." "apellidos" => "Miranda-Romero" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff1" ] ] ] ] "afiliaciones" => array:3 [ 0 => array:3 [ "entidad" => "Servicio de Dermatología, Hospital Clínico Universitario de Valladolid, Valladolid, Spain" "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff1" ] 1 => array:3 [ "entidad" => "Servicio de Medicina Preventiva, Hospital Clínico Universitario de Valladolid, Valladolid, Spain" "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff2" ] 2 => array:3 [ "entidad" => "Servicio de Anatomía Patológica, Hospital Clínico Universitario de Valladolid, Valladolid, Spain" "etiqueta" => "<span class="elsevierStyleSup">c</span>" "identificador" => "aff3" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor1" "etiqueta" => "⁎" "correspondencia" => "Correspondence: Ana María Morales-Callaghan, C/ Barcelona, 67, 1<span class="elsevierStyleSup">a</span>, 50017 Zaragoza, Spain." ] ] ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Estudio de Correlación Clínica, Dermatoscópica e Histopatológica de Nevus Melanocíticos Atípicos" ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaAceptado" => "2007-09-14" "PalabrasClave" => array:2 [ "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Key words" "identificador" => "xpalclavsec84198" "palabras" => array:3 [ 0 => "atypical melanocytic nevus" 1 => "dermatoscopy" 2 => "correlation" ] ] ] "es" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palabras clave" "identificador" => "xpalclavsec84197" "palabras" => array:3 [ 0 => "nevus melanocítico atípico" 1 => "dermatoscopia" 2 => "correlación" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "en" => array:2 [ "titulo" => "Abstract" "resumen" => "<span class="elsevierStyleSectionTitle">Introduction</span><p class="elsevierStyleSimplePara elsevierViewall">Atypical melanocytic nevi are acquired melanocytic lesions that were described for the first time by Clark in studies of melanocytic nevi in patients with melanomas. Today, the use of dermatoscopy has made identification of this type of nevus much easier.</p> <span class="elsevierStyleSectionTitle">Objective</span><p class="elsevierStyleSimplePara elsevierViewall">Our aim was to study the correlation between the clinical, dermatoscopic, and histopathologic findings of melanocytic nevi and compare our findings with those of previous studies. We also aimed to investigate the value of dermatoscopy for identifying atypical melanocytic nevi.</p> <span class="elsevierStyleSectionTitle">Material and methods</span><p class="elsevierStyleSimplePara elsevierViewall">In this cross-sectional, observational study, 200 melanocytic lesions were analyzed in 166 patients examined between January 1, 2005 and December 31, 2005. We recorded the clinical, dermatoscopic, and histopathologic characteristics of each lesion and established the correlation between the different findings on a case-by-case basis. We then determined the agreement between diagnoses and assessed the value of dermatoscopy for identifying atypical melanocytic melanoma.</p> <span class="elsevierStyleSectionTitle">Results</span><p class="elsevierStyleSimplePara elsevierViewall">The clinical characteristics associated with atypical histology were a macular component (<span class="elsevierStyleItalic">P</span><.001), irregular borders, and presence of 3 or more colors. Asymmetry, diameter greater than 5 or 6 mm, and progression were not associated with atypical histopathologic characteristics (<span class="elsevierStyleItalic">P</span>>.05). Agreement between clinical and histologic diagnosis was weak (κ=0.38), whereas the agreement between dermatoscopic and histologic diagnosis was moderate (κ=0.52). The area under the receiver operating characteristic curve for the model that included dermatoscopy was larger than that for the model that only included clinical data, and this difference was statistically significant.</p> <span class="elsevierStyleSectionTitle">Conclusions</span><p class="elsevierStyleSimplePara elsevierViewall">Atypical clinical features were not found to correspond to atypical histology. Dermatoscopy improved the accuracy of clinical diagnosis of atypical melanocytic nevus.</p>" ] "es" => array:2 [ "titulo" => "Resumen" "resumen" => "<span class="elsevierStyleSectionTitle">Introducción</span><p class="elsevierStyleSimplePara elsevierViewall">Los nevus melanocíticos atípicos (NMA) son lesiones melanocíticas adquiridas descritas por primera vez por Clark en estudios de nevus melanocíticos (NM) en pacientes con melanomas. Actualmente, el uso de la dermatoscopia ha facilitado en gran medida la identificación de esta variante de nevus.</p> <span class="elsevierStyleSectionTitle">Objetivo</span><p class="elsevierStyleSimplePara elsevierViewall">Estudiar la correlación entre los hallazgos clínicos, dermatoscópicos e histopatológicos de los NM a estudio y comparar nuestros resultados con trabajos previos. Establecer el valor de la dermatoscopia para la identificación de NMA.</p> <span class="elsevierStyleSectionTitle">Material y métodos</span><p class="elsevierStyleSimplePara elsevierViewall">Estudio observacional, transversal de 200 lesiones melanocíticas correspondientes a 166 pacientes, llevado a cabo desde el 1 de enero de 2005 hasta el 31 de diciembre de 2005. Describimos las características clínicas, dermatoscópicas e histopatológicas de cada lesión y establecimos la correlación entre los diferentes hallazgos obtenidos, caso por caso. Posteriormente determinamos la concordancia entre diagnósticos y establecimos el valor de la dermatoscopia para la identificación de NMA.</p> <span class="elsevierStyleSectionTitle">Resultados</span><p class="elsevierStyleSimplePara elsevierViewall">Las características clínicas que se asociaron a atipia histológica fueron componente macular (p<span class="elsevierStyleHsp" style=""></span><<span class="elsevierStyleHsp" style=""></span>0,001), bordes irregulares y presencia de tres o más colores. La asimetría, diámetro mayor de 5 o 6<span class="elsevierStyleHsp" style=""></span>mm o la evolución no se correspondieron con atipia desde el punto de vista histopatológico (p<span class="elsevierStyleHsp" style=""></span>><span class="elsevierStyleHsp" style=""></span>0,05). La concordancia entre diagnóstico clínico e histológico fue baja (índice kappa ponderado [Kp]: 0,38), mientras que entre diagnóstico dermatoscópico e histológico fue moderada (índice Kp: 0,52). Mediante curvas ROC (receiver operating characteristic) comprobamos que el modelo que contenía la dermatoscopia presentaba un incremento bajo la curva estadísticamente significativo respecto al modelo que sólo incluía los datos clínicos.</p> <span class="elsevierStyleSectionTitle">Conclusiones</span><p class="elsevierStyleSimplePara elsevierViewall">La atipia clínica no es equivalente a atipia histológica. La dermatoscopia mejora la precisión del diagnóstico clínico de NMA.</p>" ] ] "bibliografia" => array:2 [ "titulo" => "References" "seccion" => array:1 [ 0 => array:1 [ "bibliografiaReferencia" => array:34 [ 0 => array:3 [ "identificador" => "bib1" "etiqueta" => "1" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Origin of familial malignant melanomas from heritable melanocytic lesions: the B-K mole syndrome" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "W.HJ. Clark" 1 => "R.R. Reimer" 2 => "M. Greene" 3 => "A.M. Ainsworth" 4 => "M.J. Mastrangelo" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Arch Dermatol" "fecha" => "1978" "volumen" => "114" "paginaInicial" => "732" "paginaFinal" => "738" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/646394" "web" => "Medline" ] ] ] ] ] ] ] ] 1 => array:3 [ "identificador" => "bib2" "etiqueta" => "2" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Cutaneous melanoma" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "H.K. Koh" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1056/NEJM199107183250306" "Revista" => array:7 [ "tituloSerie" => "N Engl J Med" "fecha" => "1991" "volumen" => "325" "paginaInicial" => "171" "paginaFinal" => "182" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/1805813" "web" => "Medline" ] ] "itemHostRev" => array:3 [ "pii" => "S0016508508018581" "estado" => "S300" "issn" => "00165085" ] ] ] ] ] ] ] 2 => array:3 [ "identificador" => "bib3" "etiqueta" => "3" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "A natural history of melanomas and dysplastic nevi: an atlas of lesions in melanoma-prone families" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "M. Tucker" 1 => "M. Fraser" 2 => "A. Goldstein" 3 => "J. Struewing" 4 => "M. King" 5 => "J. Crawford" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1002/cncr.10605" "Revista" => array:6 [ "tituloSerie" => "Cancer" "fecha" => "2002" "volumen" => "94" "paginaInicial" => "3192" "paginaFinal" => "3209" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12115352" "web" => "Medline" ] ] ] ] ] ] ] ] 3 => array:3 [ "identificador" => "bib4" "etiqueta" => "4" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Number of melanocytic nevi as a major risk for malignant melanoma" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "E.A. Holly" 1 => "J.W. Kelly" 2 => "S.N. Shpall" 3 => "S.H. Chiu" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "J Am Acad Dermatol" "fecha" => "1987" "volumen" => "17" "paginaInicial" => "459" "paginaFinal" => "468" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/3655025" "web" => "Medline" ] ] ] ] ] ] ] ] 4 => array:3 [ "identificador" => "bib5" "etiqueta" => "5" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Clinically recognized dysplastic nevi: a central risk factor for cutaneous melanoma" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "M.A. Tucker" 1 => "A. Halpern" 2 => "A.E. Holly" 3 => "P. Hartge" 4 => "D.E. Elder" 5 => "R.W. Sagebiel" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "JAMA" "fecha" => "1997" "volumen" => "227" "paginaInicial" => "1439" "paginaFinal" => "1444" ] ] ] ] ] ] 5 => array:3 [ "identificador" => "bib6" "etiqueta" => "6" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Dysplastic naevi with moderate to severe histological dysplasia: a risk factor for melanoma" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "A.R. Shors" 1 => "S. Kim" 2 => "E. White" 3 => "Z. Argenyi" 4 => "R.L. Barnhill" 5 => "P. Duray" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1111/j.1365-2133.2006.07466.x" "Revista" => array:7 [ "tituloSerie" => "Br J Dermatol" "fecha" => "2006" "volumen" => "155" "paginaInicial" => "988" "paginaFinal" => "993" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/17034530" "web" => "Medline" ] ] "itemHostRev" => array:3 [ "pii" => "S001651070802628X" "estado" => "S300" "issn" => "00165107" ] ] ] ] ] ] ] 6 => array:3 [ "identificador" => "bib7" "etiqueta" => "7" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Correlation of clinical and histopathologic features in clinically atypical melanocytic nevi" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "R. Barnhill" 1 => "G. Roush" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Cancer" "fecha" => "1991" "volumen" => "67" "paginaInicial" => "3157" "paginaFinal" => "3164" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/2044059" "web" => "Medline" ] ] ] ] ] ] ] ] 7 => array:3 [ "identificador" => "bib8" "etiqueta" => "8" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Correlation between clinical atypia and histologic dysplasia in acquired melanocytic nevi" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "G. Annessi" 1 => "M.S. Cattaruzza" 2 => "D. Abeni" 3 => "G. Baliva" 4 => "M. Laurenza" 5 => "V. Macchini" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1067/mjd.2001.114580" "Revista" => array:6 [ "tituloSerie" => "J Am Acad Dermatol" "fecha" => "2001" "volumen" => "45" "paginaInicial" => "77" "paginaFinal" => "85" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11423839" "web" => "Medline" ] ] ] ] ] ] ] ] 8 => array:3 [ "identificador" => "bib9" "etiqueta" => "9" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Dermoscopic classification of atypical nevi (Clark nevi)" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:5 [ 0 => "R. Hoffman-Wellenhof" 1 => "A. Blum" 2 => "H. Wolf" 3 => "D., K.erlH. Piccolo" 4 => "C. arbe" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Arch Dermatol" "fecha" => "2001" "volumen" => "137" "paginaInicial" => "1575" "paginaFinal" => "1580" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11735707" "web" => "Medline" ] ] ] ] ] ] ] ] 9 => array:3 [ "identificador" => "bib10" "etiqueta" => "10" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Histopathologic correlation in dermoscopy. A micropunch technique" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "R.P. Braun" 1 => "G. Kaya" 2 => "I. Masouyé" 3 => "J. Krischer" 4 => "J.H. Saurat" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Arch Dermatol" "fecha" => "2003" "volumen" => "139" "paginaInicial" => "349" "paginaFinal" => "351" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12622628" "web" => "Medline" ] ] ] ] ] ] ] ] 10 => array:3 [ "identificador" => "bib11" "etiqueta" => "11" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Surface microscopy: a new approach to the diagnosis of cutaneous pigmented tumors" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "H.P. Soyer" 1 => "J. Smolle" 2 => "S. Hödl" 3 => "H. Pachernegg" 4 => "H. Kerl" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Am J Dermatopathol" "fecha" => "1989" "volumen" => "11" "paginaInicial" => "1" "paginaFinal" => "10" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/2521782" "web" => "Medline" ] ] ] ] ] ] ] ] 11 => array:3 [ "identificador" => "bib12" "etiqueta" => "12" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Histologic correlates of structures seen on dermoscopy (epiluminescence microscopy)" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "S. Yadav" 1 => "K.A. Vossaert" 2 => "A.W. Kopf" 3 => "M. Silverman" 4 => "C. Grin-Jorgensen" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Am J Dermatopathol" "fecha" => "1993" "volumen" => "15" "paginaInicial" => "297" "paginaFinal" => "305" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8214386" "web" => "Medline" ] ] ] ] ] ] ] ] 12 => array:3 [ "identificador" => "bib13" "etiqueta" => "13" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Clinicopathological correlation of pigmented skin lesions using dermoscopy" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "H.P. Soyer" 1 => "R.O. Kenet" 2 => "I.H. Wolf" 3 => "B.J. Kenet" 4 => "L. Cerroni" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Eur J Dermatol" "fecha" => "2000" "volumen" => "10" "paginaInicial" => "22" "paginaFinal" => "28" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10694293" "web" => "Medline" ] ] ] ] ] ] ] ] 13 => array:3 [ "identificador" => "bib14" "etiqueta" => "14" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The dermoscopic classification of atypical melanocytic naevi (Clark naevi) is useful to discriminate benign from malignant melanocytic lesions" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "A. Blum" 1 => "H.P. Soyer" 2 => "C. Garbe" 3 => "H. Kerl" 4 => "G. Rassner" 5 => "R. Hoffman-Wellenhof" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Br J Dermatol" "fecha" => "2003" "volumen" => "149" "paginaInicial" => "1159" "paginaFinal" => "1164" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/14674892" "web" => "Medline" ] ] ] ] ] ] ] ] 14 => array:3 [ "identificador" => "bib15" "etiqueta" => "15" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Correlation with digital dermoscopic images can help dermatopathologists to diagnose equivocal skin tumours" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "J. Bauer" 1 => "B. Leinweber" 2 => "G. Metzler" 3 => "A. Blum" 4 => "R. Hofmann-Wellenhof" 5 => "N. Leitz" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1111/j.1365-2133.2006.07342.x" "Revista" => array:6 [ "tituloSerie" => "Br J Dermatol" "fecha" => "2006" "volumen" => "155" "paginaInicial" => "546" "paginaFinal" => "551" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16911279" "web" => "Medline" ] ] ] ] ] ] ] ] 15 => array:3 [ "identificador" => "bib16" "etiqueta" => "16" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Statistical methods for rates and proportions" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "J.L. Fleiss" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Libro" => array:4 [ "edicion" => "2nd ed." "fecha" => "1981" "editorial" => "Wiley" "editorialLocalizacion" => "New York" ] ] ] ] ] ] 16 => array:3 [ "identificador" => "bib17" "etiqueta" => "17" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Applied Logistic Regression" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "D.W. Hosmer" 1 => "S. Lemeshow" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Libro" => array:3 [ "fecha" => "2000" "editorial" => "John Wiley & sons" "editorialLocalizacion" => "New York" ] ] ] ] ] ] 17 => array:3 [ "identificador" => "bib18" "etiqueta" => "18" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Digital dermoscopy analysis for the differentiation of atypical nevi and early melanoma. A new quantitative semiology" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "L. Andreassi" 1 => "R. Perotti" 2 => "P. Rubegni" 3 => "M. Burroni" 4 => "G. Cevenini" 5 => "M. Biagioli" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:7 [ "tituloSerie" => "Arch Dermatol" "fecha" => "1999" "volumen" => "135" "paginaInicial" => "1459" "paginaFinal" => "1465" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10606050" "web" => "Medline" ] ] "itemHostRev" => array:3 [ "pii" => "S0016510709028879" "estado" => "S300" "issn" => "00165107" ] ] ] ] ] ] ] 18 => array:3 [ "identificador" => "bib19" "etiqueta" => "19" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Clinical selection of melanocytic lesions for dermoscopy decreases the identification of suspicious lesions in comparison with dermoscopy without clinical preselection" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "S. Seidenari" 1 => "C. Longo" 2 => "F. Giusti" 3 => "G. Pellacani" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1111/j.1365-2133.2006.07165.x" "Revista" => array:7 [ "tituloSerie" => "Br J Dermatol" "fecha" => "2006" "volumen" => "154" "paginaInicial" => "873" "paginaFinal" => "879" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16634889" "web" => "Medline" ] ] "itemHostRev" => array:3 [ "pii" => "S1470204509703298" "estado" => "S300" "issn" => "14702045" ] ] ] ] ] ] ] 19 => array:3 [ "identificador" => "bib20" "etiqueta" => "20" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Micro-melanoma detection: a clinical study on 206 consecutive cases of pigmented skin lesions with a diameter #< 3 mm" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "A. Bono" 1 => "E. Tolomio" 2 => "S. Trincone" 3 => "C. Bartoli" 4 => "S. Tomatis" 5 => "A. Carbone" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1111/j.1365-2133.2006.07396.x" "Revista" => array:6 [ "tituloSerie" => "Br J Dermatol" "fecha" => "2006" "volumen" => "155" "paginaInicial" => "570" "paginaFinal" => "573" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16911283" "web" => "Medline" ] ] ] ] ] ] ] ] 20 => array:3 [ "identificador" => "bib21" "etiqueta" => "21" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The use of the dermatoscope to identify early melanoma using the three-colour test" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "R.M. MacKie" 1 => "C. Fleming" 2 => "A.D. McMahon" 3 => "P. Jarret" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Br J Dermatol" "fecha" => "2002" "volumen" => "146" "paginaInicial" => "481" "paginaFinal" => "484" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11952549" "web" => "Medline" ] ] ] ] ] ] ] ] 21 => array:3 [ "identificador" => "bib22" "etiqueta" => "22" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Dermatoscopic differences between atypical melanocytic naevi and thin malignant melanomas" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "T. Fikrle" 1 => "K. Pizinger" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1097/01.cmr.0000195700.42766.23" "Revista" => array:6 [ "tituloSerie" => "Melanoma Res" "fecha" => "2006" "volumen" => "16" "paginaInicial" => "45" "paginaFinal" => "50" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16432455" "web" => "Medline" ] ] ] ] ] ] ] ] 22 => array:3 [ "identificador" => "bib23" "etiqueta" => "23" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Diagnostic significance of the blue hue in dermoscopy of melanocytic lesions: a dermoscopic-pathologic study" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "D. Massi" 1 => "V. de Giorgi" 2 => "P. Carli" 3 => "M. Santucci" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Am J Dermatopathol" "fecha" => "2001" "volumen" => "23" "paginaInicial" => "463" "paginaFinal" => "469" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11801781" "web" => "Medline" ] ] ] ] ] ] ] ] 23 => array:3 [ "identificador" => "bib24" "etiqueta" => "24" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Features of regression in dermoscopic diagnosis: a confounding factor? Two clinical, dermoscopic-pathologic case studies" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "V. De Giorgi" 1 => "D. Massi" 2 => "C. Salvini" 3 => "S. Sestini" 4 => "P. Carli" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Dermatol Surg" "fecha" => "2006" "volumen" => "32" "paginaInicial" => "282" "paginaFinal" => "286" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16442056" "web" => "Medline" ] ] ] ] ] ] ] ] 24 => array:3 [ "identificador" => "bib25" "etiqueta" => "25" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Clinically equivocal melanocytic skin lesions with features of regression: a dermoscopic-pathological study" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "I. Zaludek" 1 => "G. Argenziano" 2 => "G. Ferrara" 3 => "H.P. Soyer" 4 => "R. Corona" 5 => "F. Sera" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Br J Dermatol" "fecha" => "2004" "volumen" => "150" "paginaInicial" => "64" "paginaFinal" => "71" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/14746618" "web" => "Medline" ] ] ] ] ] ] ] ] 25 => array:3 [ "identificador" => "bib26" "etiqueta" => "26" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Interobserver variability on the histopathologic diagnosis of cutaneous melanoma and other pigmented skin lesions" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "R. Corona" 1 => "A. Mele" 2 => "M. Amini" 3 => "G. de Rosa" 4 => "G. Coppola" 5 => "P. Piccardi" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1200/jco.1996.14.4.1218" "Revista" => array:6 [ "tituloSerie" => "J Clin Oncol" "fecha" => "1996" "volumen" => "14" "paginaInicial" => "1218" "paginaFinal" => "1223" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8648377" "web" => "Medline" ] ] ] ] ] ] ] ] 26 => array:3 [ "identificador" => "bib27" "etiqueta" => "27" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Dermoscopic and histopathologic diagnosis of equivocal melanocytic skin lesions. An interdisciplinary study on 107 cases" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "G. Ferrara" 1 => "G. Argenziano" 2 => "H.P. Soyer" 3 => "R. Corona" 4 => "F. Sera" 5 => "B. Brubetti" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1002/cncr.10768" "Revista" => array:6 [ "tituloSerie" => "Cancer" "fecha" => "2002" "volumen" => "95" "paginaInicial" => "1094" "paginaFinal" => "1100" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12209696" "web" => "Medline" ] ] ] ] ] ] ] ] 27 => array:3 [ "identificador" => "bib28" "etiqueta" => "28" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Clinical diagnosis of dysplastic melanocytic nevi: a clinicopathologic correlation" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "J.W. Kelly" 1 => "W.A. Crutcher" 2 => "R.W. Sagebiel" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "J Am Acad Dermatol" "fecha" => "1986" "volumen" => "14" "paginaInicial" => "1044" "paginaFinal" => "1052" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/3722481" "web" => "Medline" ] ] ] ] ] ] ] ] 28 => array:3 [ "identificador" => "bib29" "etiqueta" => "29" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Histologic correlations with the clinical diagnosis of dysplastic nevus" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "W.C. Black" 1 => "W.C. Hunt" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Am J Surg Pathol" "fecha" => "1990" "volumen" => "14" "paginaInicial" => "44" "paginaFinal" => "52" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/2294780" "web" => "Medline" ] ] ] ] ] ] ] ] 29 => array:3 [ "identificador" => "bib30" "etiqueta" => "30" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Dysplastic naevus vs. in situ melanoma: digital dermoscopy analysis" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "M. Burroni" 1 => "P. Sbano" 2 => "G. Cevenini" 3 => "M. Risulo" 4 => "G. Dell’Eva" 5 => "P. Barbini" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1111/j.1365-2133.2005.06481.x" "Revista" => array:6 [ "tituloSerie" => "Br J Dermatol" "fecha" => "2005" "volumen" => "152" "paginaInicial" => "679" "paginaFinal" => "684" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15840098" "web" => "Medline" ] ] ] ] ] ] ] ] 30 => array:3 [ "identificador" => "bib31" "etiqueta" => "31" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The dermoscopic versus the clinical diagnosis of melanoma" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "C. Benelli" 1 => "E. Roscetti" 2 => "V.D. Pozzo" 3 => "G. Gasparini" 4 => "S. Cavicchini" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:7 [ "tituloSerie" => "Eur J Dermatol" "fecha" => "1999" "volumen" => "9" "paginaInicial" => "470" "paginaFinal" => "476" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10491506" "web" => "Medline" ] ] "itemHostRev" => array:3 [ "pii" => "S0016508510013223" "estado" => "S300" "issn" => "00165085" ] ] ] ] ] ] ] 31 => array:3 [ "identificador" => "bib32" "etiqueta" => "32" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "In vivo epiluminiscence microscopy of pigmented skin lesions II. Diagnosis of small pigmented skin lesions and early detection of melanoma" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "A. Steiner" 1 => "H. Pehamberger" 2 => "K. Wolf" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "J Am Acad Dermatol" "fecha" => "1987" "volumen" => "17" "paginaInicial" => "584" "paginaFinal" => "591" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/3668003" "web" => "Medline" ] ] ] ] ] ] ] ] 32 => array:3 [ "identificador" => "bib33" "etiqueta" => "33" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Diagnostic eliability of dermoscopic criteria for detecting malignant melanoma" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "H.P. Soyer" 1 => "J. Smolle" 2 => "G. Leitinger" 3 => "E. Rieger" 4 => "H. Keri" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Dermatology" "fecha" => "1995" "volumen" => "190" "paginaInicial" => "25" "paginaFinal" => "30" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/7894091" "web" => "Medline" ] ] ] ] ] ] ] ] 33 => array:3 [ "identificador" => "bib34" "etiqueta" => "34" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Systematic review of the diagnostic accuracy of dermatoscopy in detecting malignant melanoma" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "J. Mayer" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Med J Aust" "fecha" => "1997" "volumen" => "167" "paginaInicial" => "206" "paginaFinal" => "210" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9293268" "web" => "Medline" ] ] ] ] ] ] ] ] ] ] ] ] ] "idiomaDefecto" => "en" "url" => "/15782190/0000009900000005/v1_201304241433/S1578219008702713/v1_201304241433/en/main.assets" "Apartado" => array:4 [ "identificador" => "6155" "tipo" => "SECCION" "en" => array:2 [ "titulo" => "Original Articles" "idiomaDefecto" => true ] "idiomaDefecto" => "en" ] "PDF" => "https://static.elsevier.es/multimedia/15782190/0000009900000005/v1_201304241433/S1578219008702713/v1_201304241433/en/main.pdf?idApp=UINPBA000044&text.app=https://actasdermo.org/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219008702713?idApp=UINPBA000044" ]
| año/Mes | Html | Total | |
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| 2023 Enero | 26 | 34 | 60 |
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| 2022 Marzo | 31 | 56 | 87 |
| 2022 Febrero | 13 | 25 | 38 |
| 2022 Enero | 48 | 34 | 82 |
| 2021 Diciembre | 23 | 34 | 57 |
| 2021 Noviembre | 25 | 45 | 70 |
| 2021 Octubre | 27 | 46 | 73 |
| 2021 Septiembre | 18 | 45 | 63 |
| 2021 Agosto | 26 | 26 | 52 |
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| 2021 Junio | 23 | 38 | 61 |
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| 2021 Abril | 35 | 29 | 64 |
| 2021 Marzo | 47 | 21 | 68 |
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| 2020 Diciembre | 10 | 17 | 27 |
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| 2020 Octubre | 28 | 13 | 41 |
| 2020 Septiembre | 33 | 8 | 41 |
| 2020 Agosto | 19 | 18 | 37 |
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| 2020 Junio | 15 | 21 | 36 |
| 2020 Mayo | 24 | 27 | 51 |
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| 2020 Marzo | 15 | 13 | 28 |
| 2020 Febrero | 2 | 4 | 6 |
| 2020 Enero | 0 | 7 | 7 |
| 2019 Diciembre | 0 | 19 | 19 |
| 2019 Noviembre | 0 | 12 | 12 |
| 2019 Octubre | 0 | 15 | 15 |
| 2019 Septiembre | 0 | 9 | 9 |
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| 2019 Marzo | 0 | 8 | 8 |
| 2019 Febrero | 0 | 14 | 14 |
| 2019 Enero | 0 | 11 | 11 |
| 2018 Diciembre | 0 | 2 | 2 |
| 2018 Octubre | 0 | 2 | 2 |
| 2018 Septiembre | 0 | 4 | 4 |
| 2018 Agosto | 0 | 18 | 18 |
| 2018 Julio | 0 | 15 | 15 |
| 2018 Junio | 0 | 11 | 11 |
| 2018 Mayo | 0 | 14 | 14 |
| 2018 Abril | 0 | 2 | 2 |
| 2018 Marzo | 0 | 5 | 5 |
| 2018 Febrero | 15 | 8 | 23 |
| 2018 Enero | 10 | 13 | 23 |
| 2017 Diciembre | 24 | 8 | 32 |
| 2017 Noviembre | 17 | 10 | 27 |
| 2017 Octubre | 16 | 6 | 22 |
| 2017 Septiembre | 25 | 10 | 35 |
| 2017 Agosto | 40 | 9 | 49 |
| 2017 Julio | 36 | 4 | 40 |
| 2017 Junio | 43 | 9 | 52 |
| 2017 Mayo | 36 | 13 | 49 |
| 2017 Abril | 46 | 14 | 60 |
| 2017 Marzo | 37 | 12 | 49 |
| 2017 Febrero | 15 | 16 | 31 |
| 2017 Enero | 10 | 9 | 19 |
| 2016 Diciembre | 26 | 12 | 38 |
| 2016 Noviembre | 23 | 9 | 32 |
| 2016 Octubre | 31 | 21 | 52 |
| 2016 Septiembre | 57 | 9 | 66 |
| 2016 Agosto | 37 | 11 | 48 |
| 2016 Julio | 18 | 5 | 23 |
| 2016 Junio | 10 | 11 | 21 |
| 2016 Mayo | 4 | 7 | 11 |
| 2016 Abril | 5 | 4 | 9 |
| 2016 Marzo | 2 | 1 | 3 |
| 2016 Febrero | 7 | 1 | 8 |
| 2016 Enero | 6 | 7 | 13 |
| 2015 Diciembre | 12 | 1 | 13 |
| 2015 Noviembre | 15 | 1 | 16 |
| 2015 Octubre | 10 | 6 | 16 |
| 2015 Septiembre | 5 | 4 | 9 |
| 2015 Agosto | 9 | 5 | 14 |
| 2015 Julio | 24 | 5 | 29 |
| 2015 Junio | 26 | 8 | 34 |
| 2015 Mayo | 64 | 16 | 80 |
| 2015 Abril | 20 | 15 | 35 |
| 2015 Marzo | 52 | 9 | 61 |
| 2015 Febrero | 29 | 6 | 35 |
| 2015 Enero | 23 | 10 | 33 |
| 2014 Diciembre | 27 | 5 | 32 |
| 2014 Noviembre | 24 | 6 | 30 |
| 2014 Octubre | 33 | 9 | 42 |
| 2014 Septiembre | 37 | 9 | 46 |
| 2014 Agosto | 44 | 14 | 58 |
| 2014 Julio | 51 | 15 | 66 |
| 2014 Junio | 42 | 19 | 61 |
| 2014 Mayo | 43 | 15 | 58 |
| 2014 Abril | 27 | 11 | 38 |
| 2014 Marzo | 43 | 21 | 64 |
| 2014 Febrero | 28 | 26 | 54 |
| 2014 Enero | 36 | 17 | 53 |
| 2013 Diciembre | 33 | 25 | 58 |
| 2013 Noviembre | 19 | 29 | 48 |
| 2013 Octubre | 26 | 18 | 44 |
| 2013 Septiembre | 25 | 28 | 53 |
| 2013 Agosto | 28 | 51 | 79 |
| 2013 Julio | 32 | 48 | 80 |
| 2013 Junio | 32 | 34 | 66 |
| 2013 Mayo | 41 | 37 | 78 |
| 2013 Abril | 24 | 56 | 80 |
| 2013 Marzo | 31 | 27 | 58 |
| 2013 Febrero | 33 | 7 | 40 |
| 2013 Enero | 13 | 4 | 17 |
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