array:23 [
  "pii" => "S1578219008702130"
  "issn" => "15782190"
  "doi" => "10.1016/S1578-2190(08)70213-0"
  "estado" => "S300"
  "fechaPublicacion" => "2008-03-01"
  "aid" => "70213"
  "copyright" => "Academia Española de Dermatología y Venereología and Elsevier España, S.L."
  "copyrightAnyo" => "2008"
  "documento" => "article"
  "crossmark" => 0
  "subdocumento" => "sco"
  "cita" => "Actas Dermosifiliogr. 2008;99:134-7"
  "abierto" => array:3 [
    "ES" => true
    "ES2" => true
    "LATM" => true
  ]
  "gratuito" => true
  "lecturas" => array:2 [
    "total" => 3738
    "formatos" => array:3 [
      "EPUB" => 35
      "HTML" => 1925
      "PDF" => 1778
    ]
  ]
  "itemSiguiente" => array:18 [
    "pii" => "S1578219008702142"
    "issn" => "15782190"
    "doi" => "10.1016/S1578-2190(08)70214-2"
    "estado" => "S300"
    "fechaPublicacion" => "2008-03-01"
    "aid" => "70214"
    "copyright" => "Academia Española de Dermatología y Venereología and Elsevier España, S.L."
    "documento" => "article"
    "crossmark" => 0
    "subdocumento" => "sco"
    "cita" => "Actas Dermosifiliogr. 2008;99:138-44"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:2 [
      "total" => 3460
      "formatos" => array:3 [
        "EPUB" => 35
        "HTML" => 1702
        "PDF" => 1723
      ]
    ]
    "en" => array:11 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">Case reports</span>"
      "titulo" => "Waldenstr&#246;m Macroglobulinemia Associated With Cutaneous Lesions and Type I Cryoglobulinemia"
      "tienePdf" => "en"
      "tieneTextoCompleto" => 0
      "tieneResumen" => array:2 [
        0 => "en"
        1 => "es"
      ]
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "138"
          "paginaFinal" => "144"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "es" => array:1 [
          "titulo" => "Macroglobulinemia de Waldenstr&#246;m Asociada a Lesiones Cut&#225;neas y Crioglobulinemia Tipo IA"
        ]
      ]
      "contieneResumen" => array:2 [
        "en" => true
        "es" => true
      ]
      "contienePdf" => array:1 [
        "en" => true
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "J&#46; del Olmo, A&#46; Espa&#241;a, M&#46;A&#46; Idoate, C&#46; Panizo"
          "autores" => array:4 [
            0 => array:2 [
              "nombre" => "J&#46;"
              "apellidos" => "del Olmo"
            ]
            1 => array:2 [
              "nombre" => "A&#46;"
              "apellidos" => "Espa&#241;a"
            ]
            2 => array:2 [
              "nombre" => "M&#46;A&#46;"
              "apellidos" => "Idoate"
            ]
            3 => array:2 [
              "nombre" => "C&#46;"
              "apellidos" => "Panizo"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "en"
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219008702142?idApp=UINPBA000044"
    "url" => "/15782190/0000009900000002/v1_201304241426/S1578219008702142/v1_201304241426/en/main.assets"
  ]
  "itemAnterior" => array:18 [
    "pii" => "S1578219008702129"
    "issn" => "15782190"
    "doi" => "10.1016/S1578-2190(08)70212-9"
    "estado" => "S300"
    "fechaPublicacion" => "2008-03-01"
    "aid" => "70212"
    "copyright" => "Academia Espa&#241;ola de Dermatolog&#237;a y Venereolog&#237;a and Elsevier Espa&#241;a&#44; S&#46;L&#46;"
    "documento" => "article"
    "crossmark" => 0
    "subdocumento" => "fla"
    "cita" => "Actas Dermosifiliogr. 2008;99:127-33"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:2 [
      "total" => 2371
      "formatos" => array:3 [
        "EPUB" => 33
        "HTML" => 1530
        "PDF" => 808
      ]
    ]
    "en" => array:11 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">Original article</span>"
      "titulo" => "Analysis of the Demand for Dermatological Care in the Immigrant Population Served by Hospital Miguel Servet in Saragossa&#44; Spain"
      "tienePdf" => "en"
      "tieneTextoCompleto" => 0
      "tieneResumen" => array:2 [
        0 => "en"
        1 => "es"
      ]
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "127"
          "paginaFinal" => "133"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "es" => array:1 [
          "titulo" => "An&#225;lisis de la Demanda Asistencial de Dermatolog&#237;a en la Poblaci&#243;n Inmigrante del &#193;rea de Salud del Hospital Miguel Servet de Zaragoza"
        ]
      ]
      "contieneResumen" => array:2 [
        "en" => true
        "es" => true
      ]
      "contienePdf" => array:1 [
        "en" => true
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "N&#46; Porta, J&#46; San Juan, E&#46; Simal, R&#46; Baldellou, M&#46; Ara, M&#46;L&#46; Zubiri"
          "autores" => array:6 [
            0 => array:2 [
              "nombre" => "N&#46;"
              "apellidos" => "Porta"
            ]
            1 => array:2 [
              "nombre" => "J&#46;"
              "apellidos" => "San Juan"
            ]
            2 => array:2 [
              "nombre" => "E&#46;"
              "apellidos" => "Simal"
            ]
            3 => array:2 [
              "nombre" => "R&#46;"
              "apellidos" => "Baldellou"
            ]
            4 => array:2 [
              "nombre" => "M&#46;"
              "apellidos" => "Ara"
            ]
            5 => array:2 [
              "nombre" => "M&#46;L&#46;"
              "apellidos" => "Zubiri"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "en"
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219008702129?idApp=UINPBA000044"
    "url" => "/15782190/0000009900000002/v1_201304241426/S1578219008702129/v1_201304241426/en/main.assets"
  ]
  "en" => array:14 [
    "idiomaDefecto" => true
    "cabecera" => "<span class="elsevierStyleTextfn">Case reports</span>"
    "titulo" => "Keratoderma Palmoplantaris Varians &#40;Striata et Areata&#41;&#46; A Form of Chronic Idiopathic Acrokeratosis Described by Degos"
    "tieneTextoCompleto" => 0
    "paginas" => array:1 [
      0 => array:2 [
        "paginaInicial" => "134"
        "paginaFinal" => "137"
      ]
    ]
    "autores" => array:1 [
      0 => array:4 [
        "autoresLista" => "A&#46; Padial, V&#46; Morales, J&#46;C&#46; Armario-Hita, J&#46;L&#46; Ingunza, J&#46;M&#46; Fern&#225;ndez-Vozmediano"
        "autores" => array:5 [
          0 => array:2 [
            "nombre" => "A&#46;"
            "apellidos" => "Padial"
          ]
          1 => array:2 [
            "nombre" => "V&#46;"
            "apellidos" => "Morales"
          ]
          2 => array:2 [
            "nombre" => "J&#46;C&#46;"
            "apellidos" => "Armario-Hita"
          ]
          3 => array:2 [
            "nombre" => "J&#46;L&#46;"
            "apellidos" => "Ingunza"
          ]
          4 => array:4 [
            "nombre" => "J&#46;M&#46;"
            "apellidos" => "Fern&#225;ndez-Vozmediano"
            "email" => array:1 [
              0 => "fdezvozmediano&#64;dermasur&#46;com"
            ]
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">¿</span>"
                "identificador" => "cor1"
              ]
            ]
          ]
        ]
        "afiliaciones" => array:1 [
          0 => array:1 [
            "entidad" => "Servicio de Dermatolog&#237;a&#44; Hospital Universitario de Puerto Real&#44; Universidad de C&#225;diz&#44; Spain"
          ]
        ]
        "correspondencia" => array:1 [
          0 => array:3 [
            "identificador" => "cor1"
            "etiqueta" => "&#8270;"
            "correspondencia" => "Correspondence&#58; Servicio de Dermatolog&#237;a&#44; Hospital Universitario de Puerto Real&#44; C&#225;diz&#44; Spain&#46;"
          ]
        ]
      ]
    ]
    "titulosAlternativos" => array:1 [
      "es" => array:1 [
        "titulo" => "Queratodermia Palmoplantar Varians &#40;<span class="elsevierStyleItalic">Striata Et Areata</span>&#41; Tipo Acroqueratosis Esencial Cr&#243;nica de Degos"
      ]
    ]
    "pdfFichero" => "main.pdf"
    "tienePdf" => true
    "fechaAceptado" => "2007-02-08"
    "PalabrasClave" => array:2 [
      "en" => array:1 [
        0 => array:4 [
          "clase" => "keyword"
          "titulo" => "Key words"
          "identificador" => "xpalclavsec84115"
          "palabras" => array:5 [
            0 => "palmoplantar keratoderma"
            1 => "keratoderma striata"
            2 => "keratoderma <span class="elsevierStyleItalic">varians</span>"
            3 => "keratosis palmoplantaris varians"
            4 => "keratoderma of Wachters"
          ]
        ]
      ]
      "es" => array:1 [
        0 => array:4 [
          "clase" => "keyword"
          "titulo" => "Palabras clave"
          "identificador" => "xpalclavsec84116"
          "palabras" => array:5 [
            0 => "queratodermias palmoplantares"
            1 => "queratodermia estriada"
            2 => "queratodermia <span class="elsevierStyleItalic">varians</span>"
            3 => "queratosis <span class="elsevierStyleItalic">palmoplantaris varians</span>"
            4 => "queratodermia de Wachters"
          ]
        ]
      ]
    ]
    "tieneResumen" => true
    "resumen" => array:2 [
      "en" => array:2 [
        "titulo" => "Abstract"
        "resumen" => "<p class="elsevierStyleSimplePara elsevierViewall">We report a case of a 15-year-old boy with hyperkeratotic lesions that were linear or striated on the palms and nummular on the soles&#46; He was the only family member known to be affected&#44; suggesting that the condition could be attributed to a de novo mutation or the recessive form of keratoderma palmoplantaris striata&#44; described by Degos as chronic idiopathic acrokeratosis&#46; The lesions did not improve with topical treatments &#40;keratolytic agents&#44; emollients&#44; or corticosteroids&#41; or oral retinoids&#46; We observed that scratching of the affected areas was the main reason for deterioration of the lesions&#46;</p>"
      ]
      "es" => array:2 [
        "titulo" => "Resumen"
        "resumen" => "<p class="elsevierStyleSimplePara elsevierViewall">Paciente var&#243;n de 15 a&#241;os de edad con lesiones hiperquerat&#243;sicas con disposici&#243;n lineal o estriada en las palmas y numular en plantas&#46; Era el &#250;nico miembro afecto conocido de su familia&#44; por lo que se podr&#237;a tratar de una mutaci&#243;n <span class="elsevierStyleItalic">de novo</span> o de la forma recesiva de queratosis palmoplantar <span class="elsevierStyleItalic">estriata varians&#44;</span> denominada por Degos &#171;acroqueratosis esencial cr&#243;nica&#187;&#46; Las lesiones no mejoraron con los tratamientos t&#243;picos instaurados &#40;queratol&#237;ticos&#44; emolientes y corticoides&#41; ni con retinoides orales&#46; Se pudo constatar que el rozamiento o fricci&#243;n de las zonas afectas era el principal factor de empeoramiento de las mismas&#46;</p>"
      ]
    ]
    "bibliografia" => array:2 [
      "titulo" => "References"
      "seccion" => array:1 [
        0 => array:1 [
          "bibliografiaReferencia" => array:21 [
            0 => array:3 [
              "identificador" => "bib1"
              "etiqueta" => "1&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Keratodermia symmetrica palmaris et plantaris"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "S&#46;R&#46; Br&#252;nauer"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:4 [
                        "tituloSerie" => "Derm Wschr"
                        "fecha" => "1923"
                        "volumen" => "76"
                        "paginaInicial" => "116"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            1 => array:3 [
              "identificador" => "bib2"
              "etiqueta" => "2&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Zur Kenntnis der Herdweisen Keratosen and Handen und F&#252;ssen"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "J&#46; Fusch"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Acta Derm Venereol &#40;Stockh&#41;"
                        "fecha" => "1924"
                        "volumen" => "5"
                        "paginaInicial" => "11"
                        "paginaFinal" => "58"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            2 => array:3 [
              "identificador" => "bib3"
              "etiqueta" => "3&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Keratosis palmo-plantaris striata"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "H&#46;W&#46; Siemens"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Arch Derm Syph &#40;Berl&#41;"
                        "fecha" => "1929"
                        "volumen" => "157"
                        "paginaInicial" => "392"
                        "paginaFinal" => "408"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            3 => array:3 [
              "identificador" => "bib4"
              "etiqueta" => "4&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Keratosis palmoplantaris numularis &#40;&#8220;hereditary painful callosities&#8221;&#41;"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "D&#46;H&#46; Wachters"
                            1 => "E&#46;L&#46; Frensdorf"
                            2 => "R&#46; Hausman"
                            3 => "E&#46; van Dijk"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "J Am Acad Dermatol"
                        "fecha" => "1983"
                        "volumen" => "9"
                        "paginaInicial" => "204"
                        "paginaFinal" => "209"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/6224824"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            4 => array:3 [
              "identificador" => "bib5"
              "etiqueta" => "5&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Striate palmoplantar keratoderma"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "K&#46;L&#46; White"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Dermatol Online J"
                        "fecha" => "2002"
                        "volumen" => "8"
                        "paginaInicial" => "16"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12546771"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            5 => array:3 [
              "identificador" => "bib6"
              "etiqueta" => "6&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "The hereditary palmoplantar keratoses&#58; an updated review and classification"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "G&#46;P&#46; Lucker"
                            1 => "P&#46;C&#46; van de Kerkhof"
                            2 => "P&#46;M&#46; Steijlen"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Br J Dermatol"
                        "fecha" => "1994"
                        "volumen" => "131"
                        "paginaInicial" => "1"
                        "paginaFinal" => "14"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8043399"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            6 => array:3 [
              "identificador" => "bib7"
              "etiqueta" => "7&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Localization of a locus for the striated form of palmoplantar keratoderma to chromosome 18q near the desmosomal cadherin gene cluster"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "H&#46;C&#46; Hennies"
                            1 => "W&#46; Kuster"
                            2 => "D&#46; Mischke"
                            3 => "A&#46; Reis"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Hum Mol Genet"
                        "fecha" => "1995"
                        "volumen" => "4"
                        "paginaInicial" => "1015"
                        "paginaFinal" => "1020"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/7544663"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            7 => array:3 [
              "identificador" => "bib8"
              "etiqueta" => "8&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Striate palmoplantar keratoderma arising from desmoplakin and desmoglein 1 mutations is associated with contrasting perturbations of desmosomes and the keratin filament network"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "H&#46; Wan"
                            1 => "P&#46;JC&#46; Dopping-Hepenstal"
                            2 => "M&#46;J&#46; Gratian"
                            3 => "M&#46;F&#46; Stone"
                            4 => "G&#46; Zhu"
                            5 => "P&#46;E&#46; Purkis"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1111/j.1365-2133.2004.05996.x"
                      "Revista" => array:6 [
                        "tituloSerie" => "Br J Dermatol"
                        "fecha" => "2004"
                        "volumen" => "150"
                        "paginaInicial" => "878"
                        "paginaFinal" => "891"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15149499"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            8 => array:3 [
              "identificador" => "bib9"
              "etiqueta" => "9&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Palmoplantar keratoderma"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "S&#46;B&#46; Mallory"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Libro" => array:5 [
                        "edicion" => "Second Edition"
                        "titulo" => "An illustrated dictionary of dermatologic syndromes"
                        "fecha" => "2006"
                        "editorial" => "Taylor &#38; Francis"
                        "editorialLocalizacion" => "London"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            9 => array:3 [
              "identificador" => "bib10"
              "etiqueta" => "10&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Striate keratoderma"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "R&#46; Caputo"
                            1 => "G&#46; Tadini"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Libro" => array:4 [
                        "titulo" => "Atlas of genodermatoses"
                        "fecha" => "2006"
                        "editorial" => "Taylor &#38; Francis"
                        "editorialLocalizacion" => "London"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            10 => array:3 [
              "identificador" => "bib11"
              "etiqueta" => "11&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Hereditary palmoplantar keratoderma &#40;four cases in three generations&#41;"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "V&#46;N&#46; Sehgal"
                            1 => "S&#46; Kumar"
                            2 => "S&#46; Narayan"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Int J Dermatol"
                        "fecha" => "2001"
                        "volumen" => "40"
                        "paginaInicial" => "130"
                        "paginaFinal" => "132"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11328395"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            11 => array:3 [
              "identificador" => "bib12"
              "etiqueta" => "12&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Queratodermia palmoplantar focal no sindr&#243;mica&#46; Chapter 58&#46; Queratodermias"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "A&#46;L&#46; Krol"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "LibroEditado" => array:4 [
                        "titulo" => "Dermatolog&#237;a"
                        "paginaInicial" => "816"
                        "paginaFinal" => "817"
                        "serieFecha" => "2004"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            12 => array:3 [
              "identificador" => "bib13"
              "etiqueta" => "13&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Keratosis palmoplantaris varians of Wachters in a patient with acanthosis nigricans and linear and whorled nevoid hypermelanosis"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "M&#46;D&#46; Pavlovic"
                            1 => "L&#46;O&#46; Kandolf"
                            2 => "L&#46; Zolotarevski"
                            3 => "R&#46;D&#46; Zecevic"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Acta Dermatoven APA"
                        "fecha" => "2004"
                        "volumen" => "13"
                        "paginaInicial" => "95"
                        "paginaFinal" => "100"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            13 => array:3 [
              "identificador" => "bib14"
              "etiqueta" => "14&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Keratosis palmoplantaris varians of Wachters"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "S&#46; Paoli"
                            1 => "A&#46; Mastrolorenzo"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "J Eur Acad Dermatol Venereol"
                        "fecha" => "1999"
                        "volumen" => "12"
                        "paginaInicial" => "33"
                        "paginaFinal" => "37"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10188147"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            14 => array:3 [
              "identificador" => "bib15"
              "etiqueta" => "15&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Frameshift mutation in the V2 domain of human keratin 1 results in striate palmoplantar keratoderma"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "N&#46;V&#46; Whittock"
                            1 => "F&#46;J&#46; Smith"
                            2 => "H&#46; Wan"
                            3 => "R&#46; Mallipeddi"
                            4 => "W&#46;A&#46; Griffiths"
                            5 => "P&#46; Dopping-Hepenstal"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1046/j.1523-1747.2002.01750.x"
                      "Revista" => array:6 [
                        "tituloSerie" => "J Invest Dermatol"
                        "fecha" => "2002"
                        "volumen" => "118"
                        "paginaInicial" => "838"
                        "paginaFinal" => "844"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11982762"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            15 => array:3 [
              "identificador" => "bib16"
              "etiqueta" => "16&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Dermatologie"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "R&#46; Degos"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Libro" => array:3 [
                        "fecha" => "1965"
                        "editorial" => "Flammarion"
                        "editorialLocalizacion" => "Paris"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            16 => array:3 [
              "identificador" => "bib17"
              "etiqueta" => "17&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Queratodermia palmoplantar tipo varians&#46; Estudio de tres familias"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "M&#46; Ortega"
                            1 => "J&#46; Quintana"
                            2 => "F&#46; Camacho"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Med Cut Iber Lat Am"
                        "fecha" => "1988"
                        "volumen" => "16"
                        "paginaInicial" => "66"
                        "paginaFinal" => "69"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            17 => array:3 [
              "identificador" => "bib18"
              "etiqueta" => "18&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "The inherited palmoplantar keratodermas"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "R&#46;C&#46; Ratnavel"
                            1 => "W&#46;A&#46;D&#46; Griffiths"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Br J Dermatol"
                        "fecha" => "1997"
                        "volumen" => "137"
                        "paginaInicial" => "485"
                        "paginaFinal" => "490"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9390321"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            18 => array:3 [
              "identificador" => "bib19"
              "etiqueta" => "19&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Keratosis palmoplantaris nummularis"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "T&#46; Nogita"
                            1 => "M&#46; Furue"
                            2 => "H&#46; Nakagawa"
                            3 => "Y&#46; Ishibashi"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "J Am Acad Dermatol"
                        "fecha" => "1991"
                        "volumen" => "25"
                        "paginaInicial" => "113"
                        "paginaFinal" => "114"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/1880239"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            19 => array:3 [
              "identificador" => "bib20"
              "etiqueta" => "20&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Treatment of palmoplantar keratoderma with continuous infusion 5-fluorouracil"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "A&#46;O&#46; Lienemann"
                            1 => "V&#46;J&#46; Colucci"
                            2 => "M&#46;S&#46; Jones"
                            3 => "J&#46;M&#46; Trauscht"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Cutis"
                        "fecha" => "2004"
                        "volumen" => "73"
                        "paginaInicial" => "303"
                        "paginaFinal" => "308"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15186044"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            20 => array:3 [
              "identificador" => "bib21"
              "etiqueta" => "21&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Keratosis punctata palmoplantaris controlled with topical retinoids&#58; a case report and review of the literature"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "M&#46;S&#46; Kong"
                            1 => "R&#46; Harford"
                            2 => "J&#46;T&#46; O&#8217;Neill"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Cutis"
                        "fecha" => "2004"
                        "volumen" => "74"
                        "paginaInicial" => "173"
                        "paginaFinal" => "179"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15499759"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
          ]
        ]
      ]
    ]
  ]
  "idiomaDefecto" => "en"
  "url" => "/15782190/0000009900000002/v1_201304241426/S1578219008702130/v1_201304241426/en/main.assets"
  "Apartado" => array:4 [
    "identificador" => "6183"
    "tipo" => "SECCION"
    "en" => array:2 [
      "titulo" => "Case Reports"
      "idiomaDefecto" => true
    ]
    "idiomaDefecto" => "en"
  ]
  "PDF" => "https://static.elsevier.es/multimedia/15782190/0000009900000002/v1_201304241426/S1578219008702130/v1_201304241426/en/main.pdf?idApp=UINPBA000044&text.app=https://actasdermo.org/"
  "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219008702130?idApp=UINPBA000044"
]
Compartir
Información de la revista

Estadísticas

Siga este enlace para acceder al texto completo del artículo

Case reports
Keratoderma Palmoplantaris Varians (Striata et Areata). A Form of Chronic Idiopathic Acrokeratosis Described by Degos
Queratodermia Palmoplantar Varians (Striata Et Areata) Tipo Acroqueratosis Esencial Crónica de Degos
A. Padial, V. Morales, J.C. Armario-Hita, J.L. Ingunza, J.M. Fernández-Vozmediano
Autor para correspondencia
fdezvozmediano@dermasur.com

Correspondence: Servicio de Dermatología, Hospital Universitario de Puerto Real, Cádiz, Spain.
Servicio de Dermatología, Hospital Universitario de Puerto Real, Universidad de Cádiz, Spain
Leído
7674
Veces
se ha leído el artículo
3743
Total PDF
3931
Total HTML
Compartir estadísticas
 array:23 [
  "pii" => "S1578219008702130"
  "issn" => "15782190"
  "doi" => "10.1016/S1578-2190(08)70213-0"
  "estado" => "S300"
  "fechaPublicacion" => "2008-03-01"
  "aid" => "70213"
  "copyright" => "Academia Espa&#241;ola de Dermatolog&#237;a y Venereolog&#237;a and Elsevier Espa&#241;a&#44; S&#46;L&#46;"
  "copyrightAnyo" => "2008"
  "documento" => "article"
  "crossmark" => 0
  "subdocumento" => "sco"
  "cita" => "Actas Dermosifiliogr. 2008;99:134-7"
  "abierto" => array:3 [
    "ES" => true
    "ES2" => true
    "LATM" => true
  ]
  "gratuito" => true
  "lecturas" => array:2 [
    "total" => 3738
    "formatos" => array:3 [
      "EPUB" => 35
      "HTML" => 1925
      "PDF" => 1778
    ]
  ]
  "itemSiguiente" => array:18 [
    "pii" => "S1578219008702142"
    "issn" => "15782190"
    "doi" => "10.1016/S1578-2190(08)70214-2"
    "estado" => "S300"
    "fechaPublicacion" => "2008-03-01"
    "aid" => "70214"
    "copyright" => "Academia Espa&#241;ola de Dermatolog&#237;a y Venereolog&#237;a and Elsevier Espa&#241;a&#44; S&#46;L&#46;"
    "documento" => "article"
    "crossmark" => 0
    "subdocumento" => "sco"
    "cita" => "Actas Dermosifiliogr. 2008;99:138-44"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:2 [
      "total" => 3460
      "formatos" => array:3 [
        "EPUB" => 35
        "HTML" => 1702
        "PDF" => 1723
      ]
    ]
    "en" => array:11 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">Case reports</span>"
      "titulo" => "Waldenstr&#246;m Macroglobulinemia Associated With Cutaneous Lesions and Type I Cryoglobulinemia"
      "tienePdf" => "en"
      "tieneTextoCompleto" => 0
      "tieneResumen" => array:2 [
        0 => "en"
        1 => "es"
      ]
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "138"
          "paginaFinal" => "144"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "es" => array:1 [
          "titulo" => "Macroglobulinemia de Waldenstr&#246;m Asociada a Lesiones Cut&#225;neas y Crioglobulinemia Tipo IA"
        ]
      ]
      "contieneResumen" => array:2 [
        "en" => true
        "es" => true
      ]
      "contienePdf" => array:1 [
        "en" => true
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "J&#46; del Olmo, A&#46; Espa&#241;a, M&#46;A&#46; Idoate, C&#46; Panizo"
          "autores" => array:4 [
            0 => array:2 [
              "nombre" => "J&#46;"
              "apellidos" => "del Olmo"
            ]
            1 => array:2 [
              "nombre" => "A&#46;"
              "apellidos" => "Espa&#241;a"
            ]
            2 => array:2 [
              "nombre" => "M&#46;A&#46;"
              "apellidos" => "Idoate"
            ]
            3 => array:2 [
              "nombre" => "C&#46;"
              "apellidos" => "Panizo"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "en"
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219008702142?idApp=UINPBA000044"
    "url" => "/15782190/0000009900000002/v1_201304241426/S1578219008702142/v1_201304241426/en/main.assets"
  ]
  "itemAnterior" => array:18 [
    "pii" => "S1578219008702129"
    "issn" => "15782190"
    "doi" => "10.1016/S1578-2190(08)70212-9"
    "estado" => "S300"
    "fechaPublicacion" => "2008-03-01"
    "aid" => "70212"
    "copyright" => "Academia Espa&#241;ola de Dermatolog&#237;a y Venereolog&#237;a and Elsevier Espa&#241;a&#44; S&#46;L&#46;"
    "documento" => "article"
    "crossmark" => 0
    "subdocumento" => "fla"
    "cita" => "Actas Dermosifiliogr. 2008;99:127-33"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:2 [
      "total" => 2371
      "formatos" => array:3 [
        "EPUB" => 33
        "HTML" => 1530
        "PDF" => 808
      ]
    ]
    "en" => array:11 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">Original article</span>"
      "titulo" => "Analysis of the Demand for Dermatological Care in the Immigrant Population Served by Hospital Miguel Servet in Saragossa&#44; Spain"
      "tienePdf" => "en"
      "tieneTextoCompleto" => 0
      "tieneResumen" => array:2 [
        0 => "en"
        1 => "es"
      ]
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "127"
          "paginaFinal" => "133"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "es" => array:1 [
          "titulo" => "An&#225;lisis de la Demanda Asistencial de Dermatolog&#237;a en la Poblaci&#243;n Inmigrante del &#193;rea de Salud del Hospital Miguel Servet de Zaragoza"
        ]
      ]
      "contieneResumen" => array:2 [
        "en" => true
        "es" => true
      ]
      "contienePdf" => array:1 [
        "en" => true
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "N&#46; Porta, J&#46; San Juan, E&#46; Simal, R&#46; Baldellou, M&#46; Ara, M&#46;L&#46; Zubiri"
          "autores" => array:6 [
            0 => array:2 [
              "nombre" => "N&#46;"
              "apellidos" => "Porta"
            ]
            1 => array:2 [
              "nombre" => "J&#46;"
              "apellidos" => "San Juan"
            ]
            2 => array:2 [
              "nombre" => "E&#46;"
              "apellidos" => "Simal"
            ]
            3 => array:2 [
              "nombre" => "R&#46;"
              "apellidos" => "Baldellou"
            ]
            4 => array:2 [
              "nombre" => "M&#46;"
              "apellidos" => "Ara"
            ]
            5 => array:2 [
              "nombre" => "M&#46;L&#46;"
              "apellidos" => "Zubiri"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "en"
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219008702129?idApp=UINPBA000044"
    "url" => "/15782190/0000009900000002/v1_201304241426/S1578219008702129/v1_201304241426/en/main.assets"
  ]
  "en" => array:14 [
    "idiomaDefecto" => true
    "cabecera" => "<span class="elsevierStyleTextfn">Case reports</span>"
    "titulo" => "Keratoderma Palmoplantaris Varians &#40;Striata et Areata&#41;&#46; A Form of Chronic Idiopathic Acrokeratosis Described by Degos"
    "tieneTextoCompleto" => 0
    "paginas" => array:1 [
      0 => array:2 [
        "paginaInicial" => "134"
        "paginaFinal" => "137"
      ]
    ]
    "autores" => array:1 [
      0 => array:4 [
        "autoresLista" => "A&#46; Padial, V&#46; Morales, J&#46;C&#46; Armario-Hita, J&#46;L&#46; Ingunza, J&#46;M&#46; Fern&#225;ndez-Vozmediano"
        "autores" => array:5 [
          0 => array:2 [
            "nombre" => "A&#46;"
            "apellidos" => "Padial"
          ]
          1 => array:2 [
            "nombre" => "V&#46;"
            "apellidos" => "Morales"
          ]
          2 => array:2 [
            "nombre" => "J&#46;C&#46;"
            "apellidos" => "Armario-Hita"
          ]
          3 => array:2 [
            "nombre" => "J&#46;L&#46;"
            "apellidos" => "Ingunza"
          ]
          4 => array:4 [
            "nombre" => "J&#46;M&#46;"
            "apellidos" => "Fern&#225;ndez-Vozmediano"
            "email" => array:1 [
              0 => "fdezvozmediano&#64;dermasur&#46;com"
            ]
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">¿</span>"
                "identificador" => "cor1"
              ]
            ]
          ]
        ]
        "afiliaciones" => array:1 [
          0 => array:1 [
            "entidad" => "Servicio de Dermatolog&#237;a&#44; Hospital Universitario de Puerto Real&#44; Universidad de C&#225;diz&#44; Spain"
          ]
        ]
        "correspondencia" => array:1 [
          0 => array:3 [
            "identificador" => "cor1"
            "etiqueta" => "&#8270;"
            "correspondencia" => "Correspondence&#58; Servicio de Dermatolog&#237;a&#44; Hospital Universitario de Puerto Real&#44; C&#225;diz&#44; Spain&#46;"
          ]
        ]
      ]
    ]
    "titulosAlternativos" => array:1 [
      "es" => array:1 [
        "titulo" => "Queratodermia Palmoplantar Varians &#40;<span class="elsevierStyleItalic">Striata Et Areata</span>&#41; Tipo Acroqueratosis Esencial Cr&#243;nica de Degos"
      ]
    ]
    "pdfFichero" => "main.pdf"
    "tienePdf" => true
    "fechaAceptado" => "2007-02-08"
    "PalabrasClave" => array:2 [
      "en" => array:1 [
        0 => array:4 [
          "clase" => "keyword"
          "titulo" => "Key words"
          "identificador" => "xpalclavsec84115"
          "palabras" => array:5 [
            0 => "palmoplantar keratoderma"
            1 => "keratoderma striata"
            2 => "keratoderma <span class="elsevierStyleItalic">varians</span>"
            3 => "keratosis palmoplantaris varians"
            4 => "keratoderma of Wachters"
          ]
        ]
      ]
      "es" => array:1 [
        0 => array:4 [
          "clase" => "keyword"
          "titulo" => "Palabras clave"
          "identificador" => "xpalclavsec84116"
          "palabras" => array:5 [
            0 => "queratodermias palmoplantares"
            1 => "queratodermia estriada"
            2 => "queratodermia <span class="elsevierStyleItalic">varians</span>"
            3 => "queratosis <span class="elsevierStyleItalic">palmoplantaris varians</span>"
            4 => "queratodermia de Wachters"
          ]
        ]
      ]
    ]
    "tieneResumen" => true
    "resumen" => array:2 [
      "en" => array:2 [
        "titulo" => "Abstract"
        "resumen" => "<p class="elsevierStyleSimplePara elsevierViewall">We report a case of a 15-year-old boy with hyperkeratotic lesions that were linear or striated on the palms and nummular on the soles&#46; He was the only family member known to be affected&#44; suggesting that the condition could be attributed to a de novo mutation or the recessive form of keratoderma palmoplantaris striata&#44; described by Degos as chronic idiopathic acrokeratosis&#46; The lesions did not improve with topical treatments &#40;keratolytic agents&#44; emollients&#44; or corticosteroids&#41; or oral retinoids&#46; We observed that scratching of the affected areas was the main reason for deterioration of the lesions&#46;</p>"
      ]
      "es" => array:2 [
        "titulo" => "Resumen"
        "resumen" => "<p class="elsevierStyleSimplePara elsevierViewall">Paciente var&#243;n de 15 a&#241;os de edad con lesiones hiperquerat&#243;sicas con disposici&#243;n lineal o estriada en las palmas y numular en plantas&#46; Era el &#250;nico miembro afecto conocido de su familia&#44; por lo que se podr&#237;a tratar de una mutaci&#243;n <span class="elsevierStyleItalic">de novo</span> o de la forma recesiva de queratosis palmoplantar <span class="elsevierStyleItalic">estriata varians&#44;</span> denominada por Degos &#171;acroqueratosis esencial cr&#243;nica&#187;&#46; Las lesiones no mejoraron con los tratamientos t&#243;picos instaurados &#40;queratol&#237;ticos&#44; emolientes y corticoides&#41; ni con retinoides orales&#46; Se pudo constatar que el rozamiento o fricci&#243;n de las zonas afectas era el principal factor de empeoramiento de las mismas&#46;</p>"
      ]
    ]
    "bibliografia" => array:2 [
      "titulo" => "References"
      "seccion" => array:1 [
        0 => array:1 [
          "bibliografiaReferencia" => array:21 [
            0 => array:3 [
              "identificador" => "bib1"
              "etiqueta" => "1&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Keratodermia symmetrica palmaris et plantaris"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "S&#46;R&#46; Br&#252;nauer"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:4 [
                        "tituloSerie" => "Derm Wschr"
                        "fecha" => "1923"
                        "volumen" => "76"
                        "paginaInicial" => "116"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            1 => array:3 [
              "identificador" => "bib2"
              "etiqueta" => "2&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Zur Kenntnis der Herdweisen Keratosen and Handen und F&#252;ssen"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "J&#46; Fusch"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Acta Derm Venereol &#40;Stockh&#41;"
                        "fecha" => "1924"
                        "volumen" => "5"
                        "paginaInicial" => "11"
                        "paginaFinal" => "58"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            2 => array:3 [
              "identificador" => "bib3"
              "etiqueta" => "3&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Keratosis palmo-plantaris striata"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "H&#46;W&#46; Siemens"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Arch Derm Syph &#40;Berl&#41;"
                        "fecha" => "1929"
                        "volumen" => "157"
                        "paginaInicial" => "392"
                        "paginaFinal" => "408"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            3 => array:3 [
              "identificador" => "bib4"
              "etiqueta" => "4&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Keratosis palmoplantaris numularis &#40;&#8220;hereditary painful callosities&#8221;&#41;"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "D&#46;H&#46; Wachters"
                            1 => "E&#46;L&#46; Frensdorf"
                            2 => "R&#46; Hausman"
                            3 => "E&#46; van Dijk"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "J Am Acad Dermatol"
                        "fecha" => "1983"
                        "volumen" => "9"
                        "paginaInicial" => "204"
                        "paginaFinal" => "209"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/6224824"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            4 => array:3 [
              "identificador" => "bib5"
              "etiqueta" => "5&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Striate palmoplantar keratoderma"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "K&#46;L&#46; White"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Dermatol Online J"
                        "fecha" => "2002"
                        "volumen" => "8"
                        "paginaInicial" => "16"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12546771"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            5 => array:3 [
              "identificador" => "bib6"
              "etiqueta" => "6&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "The hereditary palmoplantar keratoses&#58; an updated review and classification"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "G&#46;P&#46; Lucker"
                            1 => "P&#46;C&#46; van de Kerkhof"
                            2 => "P&#46;M&#46; Steijlen"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Br J Dermatol"
                        "fecha" => "1994"
                        "volumen" => "131"
                        "paginaInicial" => "1"
                        "paginaFinal" => "14"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8043399"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            6 => array:3 [
              "identificador" => "bib7"
              "etiqueta" => "7&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Localization of a locus for the striated form of palmoplantar keratoderma to chromosome 18q near the desmosomal cadherin gene cluster"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "H&#46;C&#46; Hennies"
                            1 => "W&#46; Kuster"
                            2 => "D&#46; Mischke"
                            3 => "A&#46; Reis"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Hum Mol Genet"
                        "fecha" => "1995"
                        "volumen" => "4"
                        "paginaInicial" => "1015"
                        "paginaFinal" => "1020"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/7544663"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            7 => array:3 [
              "identificador" => "bib8"
              "etiqueta" => "8&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Striate palmoplantar keratoderma arising from desmoplakin and desmoglein 1 mutations is associated with contrasting perturbations of desmosomes and the keratin filament network"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "H&#46; Wan"
                            1 => "P&#46;JC&#46; Dopping-Hepenstal"
                            2 => "M&#46;J&#46; Gratian"
                            3 => "M&#46;F&#46; Stone"
                            4 => "G&#46; Zhu"
                            5 => "P&#46;E&#46; Purkis"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1111/j.1365-2133.2004.05996.x"
                      "Revista" => array:6 [
                        "tituloSerie" => "Br J Dermatol"
                        "fecha" => "2004"
                        "volumen" => "150"
                        "paginaInicial" => "878"
                        "paginaFinal" => "891"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15149499"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            8 => array:3 [
              "identificador" => "bib9"
              "etiqueta" => "9&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Palmoplantar keratoderma"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "S&#46;B&#46; Mallory"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Libro" => array:5 [
                        "edicion" => "Second Edition"
                        "titulo" => "An illustrated dictionary of dermatologic syndromes"
                        "fecha" => "2006"
                        "editorial" => "Taylor &#38; Francis"
                        "editorialLocalizacion" => "London"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            9 => array:3 [
              "identificador" => "bib10"
              "etiqueta" => "10&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Striate keratoderma"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "R&#46; Caputo"
                            1 => "G&#46; Tadini"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Libro" => array:4 [
                        "titulo" => "Atlas of genodermatoses"
                        "fecha" => "2006"
                        "editorial" => "Taylor &#38; Francis"
                        "editorialLocalizacion" => "London"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            10 => array:3 [
              "identificador" => "bib11"
              "etiqueta" => "11&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Hereditary palmoplantar keratoderma &#40;four cases in three generations&#41;"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "V&#46;N&#46; Sehgal"
                            1 => "S&#46; Kumar"
                            2 => "S&#46; Narayan"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Int J Dermatol"
                        "fecha" => "2001"
                        "volumen" => "40"
                        "paginaInicial" => "130"
                        "paginaFinal" => "132"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11328395"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            11 => array:3 [
              "identificador" => "bib12"
              "etiqueta" => "12&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Queratodermia palmoplantar focal no sindr&#243;mica&#46; Chapter 58&#46; Queratodermias"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "A&#46;L&#46; Krol"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "LibroEditado" => array:4 [
                        "titulo" => "Dermatolog&#237;a"
                        "paginaInicial" => "816"
                        "paginaFinal" => "817"
                        "serieFecha" => "2004"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            12 => array:3 [
              "identificador" => "bib13"
              "etiqueta" => "13&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Keratosis palmoplantaris varians of Wachters in a patient with acanthosis nigricans and linear and whorled nevoid hypermelanosis"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "M&#46;D&#46; Pavlovic"
                            1 => "L&#46;O&#46; Kandolf"
                            2 => "L&#46; Zolotarevski"
                            3 => "R&#46;D&#46; Zecevic"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Acta Dermatoven APA"
                        "fecha" => "2004"
                        "volumen" => "13"
                        "paginaInicial" => "95"
                        "paginaFinal" => "100"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            13 => array:3 [
              "identificador" => "bib14"
              "etiqueta" => "14&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Keratosis palmoplantaris varians of Wachters"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "S&#46; Paoli"
                            1 => "A&#46; Mastrolorenzo"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "J Eur Acad Dermatol Venereol"
                        "fecha" => "1999"
                        "volumen" => "12"
                        "paginaInicial" => "33"
                        "paginaFinal" => "37"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10188147"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            14 => array:3 [
              "identificador" => "bib15"
              "etiqueta" => "15&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Frameshift mutation in the V2 domain of human keratin 1 results in striate palmoplantar keratoderma"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "N&#46;V&#46; Whittock"
                            1 => "F&#46;J&#46; Smith"
                            2 => "H&#46; Wan"
                            3 => "R&#46; Mallipeddi"
                            4 => "W&#46;A&#46; Griffiths"
                            5 => "P&#46; Dopping-Hepenstal"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1046/j.1523-1747.2002.01750.x"
                      "Revista" => array:6 [
                        "tituloSerie" => "J Invest Dermatol"
                        "fecha" => "2002"
                        "volumen" => "118"
                        "paginaInicial" => "838"
                        "paginaFinal" => "844"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11982762"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            15 => array:3 [
              "identificador" => "bib16"
              "etiqueta" => "16&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Dermatologie"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "R&#46; Degos"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Libro" => array:3 [
                        "fecha" => "1965"
                        "editorial" => "Flammarion"
                        "editorialLocalizacion" => "Paris"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            16 => array:3 [
              "identificador" => "bib17"
              "etiqueta" => "17&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Queratodermia palmoplantar tipo varians&#46; Estudio de tres familias"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "M&#46; Ortega"
                            1 => "J&#46; Quintana"
                            2 => "F&#46; Camacho"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Med Cut Iber Lat Am"
                        "fecha" => "1988"
                        "volumen" => "16"
                        "paginaInicial" => "66"
                        "paginaFinal" => "69"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            17 => array:3 [
              "identificador" => "bib18"
              "etiqueta" => "18&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "The inherited palmoplantar keratodermas"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "R&#46;C&#46; Ratnavel"
                            1 => "W&#46;A&#46;D&#46; Griffiths"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Br J Dermatol"
                        "fecha" => "1997"
                        "volumen" => "137"
                        "paginaInicial" => "485"
                        "paginaFinal" => "490"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9390321"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            18 => array:3 [
              "identificador" => "bib19"
              "etiqueta" => "19&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Keratosis palmoplantaris nummularis"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "T&#46; Nogita"
                            1 => "M&#46; Furue"
                            2 => "H&#46; Nakagawa"
                            3 => "Y&#46; Ishibashi"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "J Am Acad Dermatol"
                        "fecha" => "1991"
                        "volumen" => "25"
                        "paginaInicial" => "113"
                        "paginaFinal" => "114"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/1880239"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            19 => array:3 [
              "identificador" => "bib20"
              "etiqueta" => "20&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Treatment of palmoplantar keratoderma with continuous infusion 5-fluorouracil"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "A&#46;O&#46; Lienemann"
                            1 => "V&#46;J&#46; Colucci"
                            2 => "M&#46;S&#46; Jones"
                            3 => "J&#46;M&#46; Trauscht"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Cutis"
                        "fecha" => "2004"
                        "volumen" => "73"
                        "paginaInicial" => "303"
                        "paginaFinal" => "308"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15186044"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            20 => array:3 [
              "identificador" => "bib21"
              "etiqueta" => "21&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Keratosis punctata palmoplantaris controlled with topical retinoids&#58; a case report and review of the literature"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "M&#46;S&#46; Kong"
                            1 => "R&#46; Harford"
                            2 => "J&#46;T&#46; O&#8217;Neill"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Cutis"
                        "fecha" => "2004"
                        "volumen" => "74"
                        "paginaInicial" => "173"
                        "paginaFinal" => "179"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15499759"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
          ]
        ]
      ]
    ]
  ]
  "idiomaDefecto" => "en"
  "url" => "/15782190/0000009900000002/v1_201304241426/S1578219008702130/v1_201304241426/en/main.assets"
  "Apartado" => array:4 [
    "identificador" => "6183"
    "tipo" => "SECCION"
    "en" => array:2 [
      "titulo" => "Case Reports"
      "idiomaDefecto" => true
    ]
    "idiomaDefecto" => "en"
  ]
  "PDF" => "https://static.elsevier.es/multimedia/15782190/0000009900000002/v1_201304241426/S1578219008702130/v1_201304241426/en/main.pdf?idApp=UINPBA000044&text.app=https://actasdermo.org/"
  "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219008702130?idApp=UINPBA000044"
]
Información del artículo
ISSN: 15782190
Idioma original: Inglés
Datos actualizados diariamente
año/Mes Html Pdf Total
2024 Noviembre 8 10 18
2024 Octubre 70 53 123
2024 Septiembre 68 42 110
2024 Agosto 88 90 178
2024 Julio 65 41 106
2024 Junio 67 43 110
2024 Mayo 57 41 98
2024 Abril 71 39 110
2024 Marzo 54 61 115
2024 Febrero 63 52 115
2024 Enero 47 51 98
2023 Diciembre 38 46 84
2023 Noviembre 44 45 89
2023 Octubre 56 40 96
2023 Septiembre 41 37 78
2023 Agosto 36 37 73
2023 Julio 33 61 94
2023 Junio 46 33 79
2023 Mayo 41 30 71
2023 Abril 47 33 80
2023 Marzo 39 35 74
2023 Febrero 19 27 46
2023 Enero 24 42 66
2022 Diciembre 44 33 77
2022 Noviembre 18 33 51
2022 Octubre 18 17 35
2022 Septiembre 15 33 48
2022 Agosto 16 34 50
2022 Julio 13 24 37
2022 Junio 24 30 54
2022 Mayo 28 40 68
2022 Abril 33 37 70
2022 Marzo 30 47 77
2022 Febrero 29 31 60
2022 Enero 28 37 65
2021 Diciembre 21 40 61
2021 Noviembre 32 39 71
2021 Octubre 24 47 71
2021 Septiembre 24 40 64
2021 Agosto 17 18 35
2021 Julio 17 31 48
2021 Junio 25 26 51
2021 Mayo 19 26 45
2021 Abril 22 53 75
2021 Marzo 55 9 64
2021 Febrero 51 33 84
2021 Enero 28 13 41
2020 Diciembre 24 15 39
2020 Noviembre 28 23 51
2020 Octubre 16 9 25
2020 Septiembre 33 15 48
2020 Agosto 22 22 44
2020 Julio 44 4 48
2020 Junio 20 28 48
2020 Mayo 21 28 49
2020 Abril 20 19 39
2020 Marzo 22 35 57
2020 Febrero 3 10 13
2020 Enero 0 23 23
2019 Diciembre 0 24 24
2019 Noviembre 0 24 24
2019 Octubre 0 18 18
2019 Septiembre 0 34 34
2019 Agosto 0 26 26
2019 Julio 0 39 39
2019 Junio 0 23 23
2019 Mayo 1 114 115
2019 Abril 0 69 69
2019 Marzo 0 30 30
2019 Febrero 0 18 18
2019 Enero 0 14 14
2018 Septiembre 0 6 6
2018 Agosto 0 46 46
2018 Julio 0 11 11
2018 Junio 0 6 6
2018 Mayo 0 8 8
2018 Abril 0 11 11
2018 Marzo 1 7 8
2018 Febrero 13 15 28
2018 Enero 15 12 27
2017 Diciembre 26 12 38
2017 Noviembre 18 15 33
2017 Octubre 16 8 24
2017 Septiembre 27 22 49
2017 Agosto 26 12 38
2017 Julio 29 24 53
2017 Junio 22 22 44
2017 Mayo 24 28 52
2017 Abril 19 14 33
2017 Marzo 20 22 42
2017 Febrero 22 26 48
2017 Enero 20 16 36
2016 Diciembre 38 19 57
2016 Noviembre 36 25 61
2016 Octubre 32 29 61
2016 Septiembre 38 28 66
2016 Agosto 45 15 60
2016 Julio 29 4 33
2016 Junio 12 14 26
2016 Mayo 7 10 17
2016 Abril 5 1 6
2016 Marzo 5 30 35
2016 Febrero 6 33 39
2016 Enero 10 27 37
2015 Diciembre 8 1 9
2015 Noviembre 15 20 35
2015 Octubre 3 11 14
2015 Septiembre 5 45 50
2015 Agosto 10 8 18
2015 Julio 36 14 50
2015 Junio 66 18 84
2015 Mayo 68 21 89
2015 Abril 60 24 84
2015 Marzo 52 10 62
2015 Febrero 18 18 36
2015 Enero 38 18 56
2014 Diciembre 41 12 53
2014 Noviembre 28 21 49
2014 Octubre 66 11 77
2014 Septiembre 36 22 58
2014 Agosto 65 14 79
2014 Julio 47 26 73
2014 Junio 54 15 69
2014 Mayo 61 16 77
2014 Abril 51 25 76
2014 Marzo 57 22 79
2014 Febrero 38 20 58
2014 Enero 42 29 71
2013 Diciembre 43 18 61
2013 Noviembre 41 22 63
2013 Octubre 36 21 57
2013 Septiembre 47 23 70
2013 Agosto 34 28 62
2013 Julio 43 40 83
2013 Junio 29 35 64
2013 Mayo 22 27 49
2013 Abril 24 35 59
2013 Marzo 36 31 67
2013 Febrero 31 13 44
2013 Enero 12 7 19
Mostrar todo

Siga este enlace para acceder al texto completo del artículo

Idiomas
Actas Dermo-Sifiliográficas
es en

¿Es usted profesional sanitario apto para prescribir o dispensar medicamentos?

Are you a health professional able to prescribe or dispense drugs?