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Presentation of Three Cases and Review of the Literature" "tienePdf" => "en" "tieneTextoCompleto" => "en" "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "927" "paginaFinal" => "930" ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Alopecia areata lineal: una variante clínica infrecuente. Presentación de 3 casos y revisión de la literatura" ] ] "contieneTextoCompleto" => array:1 [ "en" => true ] "contienePdf" => array:1 [ "en" => true ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:7 [ "identificador" => "fig0005" "etiqueta" => "Figure 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 1744 "Ancho" => 2007 "Tamanyo" => 681783 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Linear alopecia areata. (A) Linear alopecic patch extending from the vertex to the left occipital area, following Blashko's lines. (B) Blashko's lines on the head. (C) Linear alopecic patch along the interparietal area. (D) Trichoscopy shows black dots, pigtail hairs and exclamation mark hairs (FotoFinder® medicam 1000, Fotofinder systems, Germany). (E) Linear alopecic patch on the frontal and left parietal area.</p>" ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "J. Piquero-Casals, D. Morgado-Carrasco, D. Saceda-Corralo, C. Peña-Penabad" "autores" => array:4 [ 0 => array:2 [ "nombre" => "J." "apellidos" => "Piquero-Casals" ] 1 => array:2 [ "nombre" => "D." "apellidos" => "Morgado-Carrasco" ] 2 => array:2 [ "nombre" => "D." "apellidos" => "Saceda-Corralo" ] 3 => array:2 [ "nombre" => "C." "apellidos" => "Peña-Penabad" ] ] ] ] ] "idiomaDefecto" => "en" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0001731023006816?idApp=UINPBA000044" "url" => "/00017310/0000011500000009/v2_202410160548/S0001731023006816/v2_202410160548/en/main.assets" ] "itemAnterior" => array:18 [ "pii" => "S0001731023008116" "issn" => "00017310" "doi" => "10.1016/j.ad.2022.11.023" "estado" => "S300" "fechaPublicacion" => "2024-10-01" "aid" => "3680" "copyright" => "AEDV" "documento" => "simple-article" "crossmark" => 1 "subdocumento" => "crp" "cita" => "Actas Dermosifiliogr. 2024;115:925-6" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:1 [ "total" => 0 ] "es" => array:11 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Carta científico-clínica</span>" "titulo" => "Enfermedad de Mondor del pene tras biopsia selectiva de ganglio centinela por melanoma" "tienePdf" => "es" "tieneTextoCompleto" => "es" "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "925" "paginaFinal" => "926" ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Mondor Disease of the Penis After Sentinel Lymph Node Biopsy in a Patient With Melanoma" ] ] "contieneTextoCompleto" => array:1 [ "es" => true ] "contienePdf" => array:1 [ "es" => true ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:7 [ "identificador" => "fig0005" "etiqueta" => "Figura 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 1583 "Ancho" => 1625 "Tamanyo" => 375661 ] ] "descripcion" => array:1 [ "es" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Imagen clínica del cordón subcutáneo indurado. Dicho cordón seguía un trayecto lineal a lo largo del dorso del pene y tenía una amplitud de 4<span class="elsevierStyleHsp" style=""></span>mm.</p>" ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "D. Marín-Piñero, G. Melé-Ninot, M. Quintana-Codina" "autores" => array:3 [ 0 => array:2 [ "nombre" => "D." "apellidos" => "Marín-Piñero" ] 1 => array:2 [ "nombre" => "G." "apellidos" => "Melé-Ninot" ] 2 => array:2 [ "nombre" => "M." "apellidos" => "Quintana-Codina" ] ] ] ] ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0001731023008116?idApp=UINPBA000044" "url" => "/00017310/0000011500000009/v2_202410160548/S0001731023008116/v2_202410160548/es/main.assets" ] "asociados" => array:1 [ 0 => array:18 [ "pii" => "S0001731023008116" "issn" => "00017310" "doi" => "10.1016/j.ad.2022.11.023" "estado" => "S300" "fechaPublicacion" => "2024-10-01" "aid" => "3680" "copyright" => "AEDV" "documento" => "simple-article" "crossmark" => 1 "subdocumento" => "crp" "cita" => "Actas Dermosifiliogr. 2024;115:925-6" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:1 [ "total" => 0 ] "es" => array:11 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Carta científico-clínica</span>" "titulo" => "Enfermedad de Mondor del pene tras biopsia selectiva de ganglio centinela por melanoma" "tienePdf" => "es" "tieneTextoCompleto" => "es" "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "925" "paginaFinal" => "926" ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Mondor Disease of the Penis After Sentinel Lymph Node Biopsy in a Patient With Melanoma" ] ] "contieneTextoCompleto" => array:1 [ "es" => true ] "contienePdf" => array:1 [ "es" => true ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:7 [ "identificador" => "fig0005" "etiqueta" => "Figura 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 1583 "Ancho" => 1625 "Tamanyo" => 375661 ] ] "descripcion" => array:1 [ "es" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Imagen clínica del cordón subcutáneo indurado. Dicho cordón seguía un trayecto lineal a lo largo del dorso del pene y tenía una amplitud de 4<span class="elsevierStyleHsp" style=""></span>mm.</p>" ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "D. Marín-Piñero, G. Melé-Ninot, M. Quintana-Codina" "autores" => array:3 [ 0 => array:2 [ "nombre" => "D." "apellidos" => "Marín-Piñero" ] 1 => array:2 [ "nombre" => "G." "apellidos" => "Melé-Ninot" ] 2 => array:2 [ "nombre" => "M." "apellidos" => "Quintana-Codina" ] ] ] ] ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0001731023008116?idApp=UINPBA000044" "url" => "/00017310/0000011500000009/v2_202410160548/S0001731023008116/v2_202410160548/es/main.assets" ] ] "en" => array:15 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Carta científico-clínica</span>" "titulo" => " Mondor Disease of the Penis After Sentinel Lymph Node Biopsy in a Patient With Melanoma" "tieneTextoCompleto" => true "saludo" => "<span class="elsevierStyleItalic">To the Editor,</span>" "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "T925" "paginaFinal" => "T926" ] ] "autores" => array:1 [ 0 => array:4 [ "autoresLista" => "D. Marín-Piñero, G. Melé-Ninot, M. Quintana-Codina" "autores" => array:3 [ 0 => array:4 [ "nombre" => "D." "apellidos" => "Marín-Piñero" "email" => array:1 [ 0 => "marindidac@gmail.com" ] "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">*</span>" "identificador" => "cor0005" ] ] ] 1 => array:2 [ "nombre" => "G." "apellidos" => "Melé-Ninot" ] 2 => array:2 [ "nombre" => "M." "apellidos" => "Quintana-Codina" ] ] "afiliaciones" => array:1 [ 0 => array:2 [ "entidad" => "Servicio de Dermatología, Hospital Universitari Sagrat Cor, Grupo Hospitalario Quirónsalud, Barcelona, Spain" "identificador" => "aff0005" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "⁎" "correspondencia" => "Corresponding author." ] ] ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Enfermedad de Mondor del pene tras biopsia selectiva de ganglio centinela por melanoma" ] ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:7 [ "identificador" => "fig0005" "etiqueta" => "Figure 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 1583 "Ancho" => 1625 "Tamanyo" => 389910 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Clinical image of the indurated subcutaneous cord, which followed a linear path along the dorsal side of the penis and was 4<span class="elsevierStyleHsp" style=""></span>mm in width.</p>" ] ] ] "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">Penile Mondor's disease (PMD) is a non-migratory and self-limited thrombophlebitis of the superficial veins of the penis. It is considered a subtype of Mondor's disease, in which thrombophlebitis is often found in the shaft.<a class="elsevierStyleCrossRefs" href="#bib0055"><span class="elsevierStyleSup">1,2</span></a> Despite being linked to multiple triggers, its specific etiopathogenesis is unknown. Diagnosis requires confirmation of thrombophlebitis, preferably via ultrasound, as well as ruling out other causes of thrombophilia.<a class="elsevierStyleCrossRefs" href="#bib0055"><span class="elsevierStyleSup">1,3</span></a> We present the first case ever reported in the literature of PMD following selective sentinel lymph node biopsy (SLNB) in the groin of a patient without risk factors for thrombosis.</p><p id="par0010" class="elsevierStylePara elsevierViewall">A 54-year-old man, with no relevant past personal history was diagnosed with a stage IIA 2.1<span class="elsevierStyleHsp" style=""></span>mm Breslow thickness melanoma in the medial lumbar region after a regular check-up. Subsequently, a surgical wide excision was performed, followed by an extension study with bilateral inguinal lymph node ultrasound which revealed no pathological findings. Additionally, a right inguinal SLNB performed tested negative. Fifteen days after surgery, he consulted for pain in the dorsal shaft of the penis. Physical examination revealed the presence of an indurated subcutaneous cord with no additional findings (<a class="elsevierStyleCrossRef" href="#fig0005">fig. 1</a>). A cutaneous ultrasound (Esaote MyLab Gamma®, linear probe of 6-18 MHz) revealed the presence of a dilated, hypoechoic, non-compressible tubular structure with hyperechoic content and no Doppler flow inside, which was consistent with thrombosis of the penis superficial dorsal vein (<a class="elsevierStyleCrossRef" href="#fig0010">fig. 2</a>). A suspected diagnosis of PMD due to inguinal SLNB followed. The patient was assessed by the urology department, which prescribed analgesic treatment with diclofenac and performed a soft tissue ultrasound that eventually confirmed the diagnosis of superficial venous thrombosis without deep involvement. The patient was also evaluated by the hematology department, which ruled out other causes of primary thrombophilia and administered low molecular weight heparin (LMWH). The course of the disease was favorable, and serial ultrasound follow-up confirmed the resolution of thrombosis after 2 months. LMWH was discontinued after resolution, and no recurrences or thrombophlebitis in other areas have been reported at the 18-month follow-up.</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><elsevierMultimedia ident="fig0010"></elsevierMultimedia><p id="par0015" class="elsevierStylePara elsevierViewall">Multiple conditions favor the occurrence of thrombosis. These are usually categorized as primary or secondary thrombophilias.<a class="elsevierStyleCrossRef" href="#bib0065"><span class="elsevierStyleSup">3</span></a> We should mention that most patients with thrombophilia will not end up developing thrombosis, and it is the addition of several predisposing factors that eventually determines its occurrence.</p><p id="par0020" class="elsevierStylePara elsevierViewall">In PMD, the main predisposing factor described is intense and prolonged sexual intercourse, which would cause endothelial microtrauma, leading to thrombus formation. Similarly, it has also been associated with direct trauma or the use of vacuum devices or intracavernosal injections in the context of erectile dysfunction.<a class="elsevierStyleCrossRef" href="#bib0055"><span class="elsevierStyleSup">1</span></a></p><p id="par0025" class="elsevierStylePara elsevierViewall">Of all the triggers described, the only one identified in our patient was a recent inguinal SLNB. Cases of PMD after pelvic surgical procedures and inguinal hernia surgeries have been reported, the latter being the most representative antecedent for our case.<a class="elsevierStyleCrossRef" href="#bib0070"><span class="elsevierStyleSup">4</span></a> Although in melanoma patients, lower limb deep vein thrombosis has been described after SLNB, no cases of penile vein thrombosis following this procedure have been reported to this date.<a class="elsevierStyleCrossRef" href="#bib0075"><span class="elsevierStyleSup">5</span></a></p><p id="par0030" class="elsevierStylePara elsevierViewall">Clinically, PMD presents as an indurated and painful subcutaneous cord located on the dorsal haft of the penis, which resolves spontaneously within 4 to 8 weeks.<a class="elsevierStyleCrossRef" href="#bib0055"><span class="elsevierStyleSup">1</span></a> Atypical forms with involvement of the circumflex or ventral veins have been described.<a class="elsevierStyleCrossRefs" href="#bib0080"><span class="elsevierStyleSup">6,7</span></a> For the diagnosis of thrombosis, the technique of choice is Doppler ultrasound.<a class="elsevierStyleCrossRefs" href="#bib0055"><span class="elsevierStyleSup">1,8</span></a> The main differential diagnosis is sclerosing lymphangitis of the penis, which presents as a self-limited indurated subcutaneous cord in the balanopreputial sulcus. Since it is a lymphatic vessel disorder, ultrasound will not show any images of venous thrombosis.<a class="elsevierStyleCrossRefs" href="#bib0055"><span class="elsevierStyleSup">1,9</span></a> Additionally, ultrasound allows us to rule out the presence of solid tumors in the shaft of the penis that may be clinically suggestive of thrombosis.<a class="elsevierStyleCrossRef" href="#bib0100"><span class="elsevierStyleSup">10</span></a></p><p id="par0035" class="elsevierStylePara elsevierViewall">There is no consensus on the need for other additional tests, which should be individualized for each patient. Therefore, multidisciplinary management is essential here. As part of the initial study, blood tests are considered appropriate to rule out causes of primary thrombophilia. Given that PMD should be a self-limited and non-migratory condition, any variation in its course would require considering an alternative diagnosis. Because of its good prognosis, conservative management with analgesics can be administered, while the jury is still out on the need for anticoagulant therapy.<a class="elsevierStyleCrossRef" href="#bib0055"><span class="elsevierStyleSup">1</span></a></p><p id="par0040" class="elsevierStylePara elsevierViewall">In conclusion, PMD should be understood as a benign and self-limited entity with multiple predisposing factors, and its diagnosis should always be one of exclusion. Of note the role of cutaneous ultrasound to both diagnose and monitor and this condition.</p><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0005">Conflicts of interest</span><p id="par0045" class="elsevierStylePara elsevierViewall">None declared.</p></span></span>" "textoCompletoSecciones" => array:1 [ "secciones" => array:2 [ 0 => array:2 [ "identificador" => "sec0005" "titulo" => "Conflicts of interest" ] 1 => array:1 [ "titulo" => "References" ] ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "multimedia" => array:2 [ 0 => array:7 [ "identificador" => "fig0005" "etiqueta" => "Figure 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 1583 "Ancho" => 1625 "Tamanyo" => 389910 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Clinical image of the indurated subcutaneous cord, which followed a linear path along the dorsal side of the penis and was 4<span class="elsevierStyleHsp" style=""></span>mm in width.</p>" ] ] 1 => array:7 [ "identificador" => "fig0010" "etiqueta" => "Figure 2" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr2.jpeg" "Alto" => 1980 "Ancho" => 1625 "Tamanyo" => 317366 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">a: B-mode ultrasound image (18 MHz) showing a hypoechoic and dilated tubular structure, which is consistent with a superficial vein. This structure was not compressible under pressure. The hyperechoic content indicated by the asterisk corresponds to the intraluminal thrombus. b: Power Doppler ultrasound image showing absence of flow inside the thrombosed vein. The image Doppler flow comes from one of the dorsal arteries of the penis.</p>" ] ] ] "bibliografia" => array:2 [ "titulo" => "References" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0015" "bibliografiaReferencia" => array:10 [ 0 => array:3 [ "identificador" => "bib0055" "etiqueta" => "1" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Evaluation and Treatment of Penile Thrombophlebitis (Mondor's Disease)" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "N.J. Manimala" 1 => "J. 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año/Mes | Html | Total | |
---|---|---|---|
2024 Noviembre | 40 | 10 | 50 |
2024 Octubre | 599 | 83 | 682 |
2024 Septiembre | 390 | 51 | 441 |
2024 Agosto | 486 | 86 | 572 |