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"apellidos" => "Cabanillas" ] ] ] ] ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0001731023005276?idApp=UINPBA000044" "url" => "/00017310/0000011400000010/v1_202311020433/S0001731023005276/v1_202311020433/es/main.assets" ] "asociados" => array:1 [ 0 => array:18 [ "pii" => "S0001731023005276" "issn" => "00017310" "doi" => "10.1016/j.ad.2023.05.027" "estado" => "S300" "fechaPublicacion" => "2023-11-01" "aid" => "3573" "copyright" => "AEDV" "documento" => "simple-article" "crossmark" => 1 "subdocumento" => "cor" "cita" => "Actas Dermosifiliogr. 2023;114:926" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:1 [ "total" => 0 ] "es" => array:10 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Carta al Director</span>" "titulo" => "Comentario a «Epidemia de escabiosis: los nuevos retos de una enfermedad ancestral»" "tienePdf" => "es" "tieneTextoCompleto" => "es" "paginas" => array:1 [ 0 => array:1 [ "paginaInicial" => "926" ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Comment on «Epidemic Scabies: New Treatment Challenges in an Ancient Disease»" ] ] "contieneTextoCompleto" => array:1 [ "es" => true ] "contienePdf" => array:1 [ "es" => true ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "Ó. Suárez-Amor, B. Monteagudo, M. Cabanillas" "autores" => array:3 [ 0 => array:2 [ "nombre" => "Ó." "apellidos" => "Suárez-Amor" ] 1 => array:2 [ "nombre" => "B." "apellidos" => "Monteagudo" ] 2 => array:2 [ "nombre" => "M." "apellidos" => "Cabanillas" ] ] ] ] ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0001731023005276?idApp=UINPBA000044" "url" => "/00017310/0000011400000010/v1_202311020433/S0001731023005276/v1_202311020433/es/main.assets" ] ] "en" => array:13 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Letter to the Editor</span>" "titulo" => " Comment on “Epidemic Scabies: New Treatment Challenges in an Ancient Disease”" "tieneTextoCompleto" => true "saludo" => "<span class="elsevierStyleItalic">To the Editor,</span>" "paginas" => array:1 [ 0 => array:1 [ "paginaInicial" => "T926" ] ] "autores" => array:1 [ 0 => array:4 [ "autoresLista" => "Ó. Suárez-Amor, B. Monteagudo, M. Cabanillas" "autores" => array:3 [ 0 => array:4 [ "nombre" => "Ó." "apellidos" => "Suárez-Amor" "email" => array:1 [ 0 => "osuamo@yahoo.es" ] "referencia" => array:2 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] 1 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">*</span>" "identificador" => "cor0005" ] ] ] 1 => array:3 [ "nombre" => "B." "apellidos" => "Monteagudo" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff0010" ] ] ] 2 => array:3 [ "nombre" => "M." "apellidos" => "Cabanillas" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] ] ] ] "afiliaciones" => array:2 [ 0 => array:3 [ "entidad" => "Dermatología, Hospital Ribera Juan Cardona, Ferrol, Spain" "etiqueta" => "a" "identificador" => "aff0005" ] 1 => array:3 [ "entidad" => "Servicio de Dermatología, Complejo Hospitalario Universitario de Ferrol, Ferrol, Spain" "etiqueta" => "b" "identificador" => "aff0010" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "⁎" "correspondencia" => "Corresponding author." ] ] ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Comentario a «Epidemia de escabiosis: los nuevos retos de una enfermedad ancestral»" ] ] "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">We read with interest the article by Lluch-Galcerá et al.<a class="elsevierStyleCrossRef" href="#bib0050"><span class="elsevierStyleSup">1</span></a> on the current scabies epidemic. First, we would like to commend the authors on their excellent review of this topic. We would also like to add a small point and clarify a controversial issue regarding the use of oral ivermectin, which we think stems from a section of the summary of product characteristics that currently states “the influence of food on absorption is unknown”.<a class="elsevierStyleCrossRef" href="#bib0055"><span class="elsevierStyleSup">2</span></a></p><p id="par0010" class="elsevierStylePara elsevierViewall">The bioavailability of ivermectin is increased by the intake of food, particularly fatty food.<a class="elsevierStyleCrossRef" href="#bib0060"><span class="elsevierStyleSup">3</span></a> What differs in the studies published to date is the intensity of the effect, which ranges from zero to a 2.6-fold increase.<a class="elsevierStyleCrossRef" href="#bib0065"><span class="elsevierStyleSup">4</span></a> The discrepancies could be linked to the different doses of ivermectin used in the respective studies.<a class="elsevierStyleCrossRef" href="#bib0065"><span class="elsevierStyleSup">4</span></a></p><p id="par0015" class="elsevierStylePara elsevierViewall">In their article, Lluch-Galcerá et al.<a class="elsevierStyleCrossRef" href="#bib0050"><span class="elsevierStyleSup">1</span></a> indicate that ivermectin should be taken after fasting, and this is indeed stipulated in several guidelines, including the German guidelines on the diagnosis and treatment of scabies.<a class="elsevierStyleCrossRef" href="#bib0070"><span class="elsevierStyleSup">5</span></a> Most authors, however, believe that ivermectin should be taken with fatty foods to increase its absorption and potential effectiveness.<a class="elsevierStyleCrossRefs" href="#bib0075"><span class="elsevierStyleSup">6,7</span></a> The Centers for Disease Control and Prevention<a class="elsevierStyleCrossRef" href="#bib0085"><span class="elsevierStyleSup">8</span></a> and the European Academy of Dermatology and Venereology both specifically recommend taking ivermectin with food.<a class="elsevierStyleCrossRef" href="#bib0090"><span class="elsevierStyleSup">9</span></a></p><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0005">Funding</span><p id="par0020" class="elsevierStylePara elsevierViewall">No funding of any type was received for this article.</p></span></span>" "textoCompletoSecciones" => array:1 [ "secciones" => array:2 [ 0 => array:2 [ "identificador" => "sec0005" "titulo" => "Funding" ] 1 => array:1 [ "titulo" => "References" ] ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "bibliografia" => array:2 [ "titulo" => "References" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0015" "bibliografiaReferencia" => array:9 [ 0 => array:3 [ "identificador" => "bib0050" "etiqueta" => "1" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Epidemia de escabiosis: los nuevos retos de una enfermedad ancestral" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "J.J. Lluch-Galcerá" 1 => "J.M. Carrascosa" 2 => "A. Boada" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/j.ad.2022.07.017" "Revista" => array:6 [ "tituloSerie" => "Actas Dermosifiliogr" "fecha" => "2023" "volumen" => "114" "paginaInicial" => "132" "paginaFinal" => "140" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/35963332" "web" => "Medline" ] ] ] ] ] ] ] ] 1 => array:3 [ "identificador" => "bib0055" "etiqueta" => "2" "referencia" => array:1 [ 0 => array:1 [ "referenciaCompleta" => "Ficha técnica. Available from: <a target="_blank" href="https://cima.aemps.es/cima/pdfs/es/ft/85728/FT_85728.pdf">https://cima.aemps.es/cima/pdfs/es/ft/85728/FT_85728.pdf</a> [cited 2023 May 1]." ] ] ] 2 => array:3 [ "identificador" => "bib0060" "etiqueta" => "3" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Systemic antiparasitic agents" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "C.A. Elston" 1 => "D.M. Elston" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "LibroEditado" => array:5 [ "editores" => "S.E.Wolverton, J.J.Wu" "titulo" => "Comprehensive dermatologic drug therapy" "paginaInicial" => "126" "paginaFinal" => "128" "serieFecha" => "2021" ] ] ] ] ] ] 3 => array:3 [ "identificador" => "bib0065" "etiqueta" => "4" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The effect of food on the pharmacokinetics of oral ivermectin" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "U. Duthaler" 1 => "R. Leisegang" 2 => "M.O. Karlsson" 3 => "S. Krähenbühl" 4 => "F. 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