LETTER TO THE EDITOR
Transverse-section histology for parallel-ridge pattern: reply
Sección histológica horizontal para el patrón de la cresta: réplica
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Torchia" "autores" => array:1 [ 0 => array:2 [ "nombre" => "D." "apellidos" => "Torchia" ] ] ] ] ] "idiomaDefecto" => "en" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0001731010002206?idApp=UINPBA000044" "url" => "/00017310/0000010100000006/v1_201304241250/S0001731010002206/v1_201304241250/en/main.assets" ] ] "en" => array:12 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">LETTER TO THE EDITOR</span>" "titulo" => "Transverse-section histology for parallel-ridge pattern: reply" "tieneTextoCompleto" => true "saludo" => "To the editor" "paginas" => array:1 [ 0 => array:1 [ "paginaInicial" => "573" ] ] "autores" => array:1 [ 0 => array:4 [ "autoresLista" => "N. Blázquez, I. Fernández-Canedo, R. Fúnez, M. de Troya" "autores" => array:4 [ 0 => array:4 [ "nombre" => "N." "apellidos" => "Blázquez" "email" => array:1 [ 0 => "nuriaderm1@gmail.com" ] "referencia" => array:2 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff1" ] 1 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">¿</span>" "identificador" => "cor1" ] ] ] 1 => array:3 [ "nombre" => "I." "apellidos" => "Fernández-Canedo" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff1" ] ] ] 2 => array:3 [ "nombre" => "R." "apellidos" => "Fúnez" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff2" ] ] ] 3 => array:3 [ "nombre" => "M." "apellidos" => "de Troya" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff1" ] ] ] ] "afiliaciones" => array:2 [ 0 => array:3 [ "entidad" => "Servicio de Dermatología, Hospital Costa del Sol, Marbella, Málaga, España" "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff1" ] 1 => array:3 [ "entidad" => "Servicio de Anatomía Patológica, Hospital Costa del Sol, Marbella, Málaga, España" "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff2" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor1" "etiqueta" => "⁎" "correspondencia" => "Corresponding author." ] ] ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Sección histológica horizontal para el patrón de la cresta: réplica" ] ] "textoCompleto" => "<span class="elsevierStyleSections"><p class="elsevierStylePara elsevierViewall">We do appreciate Dr. Torchia′s comments about our recent published article,<a class="elsevierStyleCrossRef" href="#bib1"><span class="elsevierStyleSup">1</span></a> suggesting new methods to optimize the diagnosis of suspect pigmented lesions featuring a parallel-ridge pattern.</p><p class="elsevierStylePara elsevierViewall">Torchia et al suggest a diagnostic algorithm for these suspicious lesions. In their approach, the specimen should be initially split in two halves in order to process each one in a different way. However, we wish to point out that the split of the biopsy specimen would make impossible the evaluation of their architectural features,<a class="elsevierStyleCrossRefs" href="#bib2"><span class="elsevierStyleSup">2,3</span></a> which nowadays constitute one basic aspect in the differential diagnosis of acral melanocytic lesions.</p><p class="elsevierStylePara elsevierViewall">They also propose that transverse histologic sectioning of biopsy specimens of patients suspected of having acral melanoma can demonstrate more efficiently the diagnostic features. In fact, the transverse section method is a cheap and affordable tool, that allows examination of all the eccrine ducts contained in a given specimen, and consequently provides more exhaustive information.<a class="elsevierStyleCrossRef" href="#bib4"><span class="elsevierStyleSup">4</span></a> Nevertheless, this technique presents some disadvantages. One the one hand, process and evaluation of horizontal sections can be more complicated and requires technical experience. On the other, dermoepidermic junction (including granulous stratum) is poorly represented.<a class="elsevierStyleCrossRef" href="#bib5"><span class="elsevierStyleSup">5</span></a> These two factors could easily lead to misdiagnose melanoma thickness, and secondarily tumor staging. In view of these considerations, we do not consider that serial horizontally cross-sectioning technique is the most adequate tool in the diagnosis of pigmented lesions. However, in future its use could be considered in some cases whenever tumor thickness was previously evaluated with specific image techniques such as in vivo confocal microscopy.<a class="elsevierStyleCrossRefs" href="#bib6"><span class="elsevierStyleSup">6,7</span></a></p><p class="elsevierStylePara elsevierViewall">We thank Dr. Torchia for his contribution, as he enrich our article and raise new issues and ideas for future studies.</p></span>" "pdfFichero" => "main.pdf" "tienePdf" => true "bibliografia" => array:2 [ "titulo" => "References" "seccion" => array:1 [ 0 => array:1 [ "bibliografiaReferencia" => array:7 [ 0 => array:3 [ "identificador" => "bib1" "etiqueta" => "1" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Patrón paralelo de la cresta en melanoma acral: importancia del procesamiento de la pieza para el diagnóstico histológico" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "N. 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