array:24 [
  "pii" => "S1578219007705243"
  "issn" => "15782190"
  "doi" => "10.1016/S1578-2190(07)70524-3"
  "estado" => "S300"
  "fechaPublicacion" => "2007-11-01"
  "aid" => "70524"
  "copyright" => "Academia Española de Dermatología y Venereología and Elsevier España, S.L."
  "copyrightAnyo" => "2007"
  "documento" => "article"
  "crossmark" => 0
  "subdocumento" => "fla"
  "cita" => "Actas Dermosifiliogr. 2007;98:594-602"
  "abierto" => array:3 [
    "ES" => true
    "ES2" => true
    "LATM" => true
  ]
  "gratuito" => true
  "lecturas" => array:2 [
    "total" => 7213
    "formatos" => array:3 [
      "EPUB" => 43
      "HTML" => 1722
      "PDF" => 5448
    ]
  ]
  "Traduccion" => array:1 [
    "es" => array:15 [
      "pii" => "13110361"
      "issn" => "00017310"
      "estado" => "S300"
      "fechaPublicacion" => "2007-11-01"
      "documento" => "article"
      "subdocumento" => "fla"
      "cita" => "Actas Dermosifiliogr. 2007;98:594-602"
      "abierto" => array:3 [
        "ES" => true
        "ES2" => true
        "LATM" => true
      ]
      "gratuito" => true
      "lecturas" => array:2 [
        "total" => 74915
        "formatos" => array:3 [
          "EPUB" => 3
          "HTML" => 60739
          "PDF" => 14173
        ]
      ]
      "es" => array:12 [
        "idiomaDefecto" => true
        "titulo" => "Alopecia frontal fibrosante. Valoración diagnóstica y terapéutica"
        "tienePdf" => array:2 [
          0 => "es"
          1 => "en"
        ]
        "tieneTextoCompleto" => "es"
        "tieneResumen" => array:2 [
          0 => "en"
          1 => "es"
        ]
        "paginas" => array:1 [
          0 => array:2 [
            "paginaInicial" => "594"
            "paginaFinal" => "602"
          ]
        ]
        "titulosAlternativos" => array:1 [
          "en" => array:1 [
            "titulo" => "Diagnostic and Therapeutic Assessment of Frontal Fibrosing Alopecia"
          ]
        ]
        "contieneResumen" => array:2 [
          "en" => true
          "es" => true
        ]
        "contieneTextoCompleto" => array:1 [
          "es" => true
        ]
        "contienePdf" => array:2 [
          "es" => true
          "en" => true
        ]
        "resumenGrafico" => array:2 [
          "original" => 0
          "multimedia" => array:8 [
            "identificador" => "fig1"
            "etiqueta" => "Figura 1"
            "tipo" => "MULTIMEDIAFIGURA"
            "mostrarFloat" => true
            "mostrarDisplay" => false
            "copyright" => "Elsevier España"
            "figura" => array:1 [
              0 => array:4 [
                "imagen" => "103v98n09-13110361fig02.jpg"
                "Alto" => 765
                "Ancho" => 959
                "Tamanyo" => 79655
              ]
            ]
            "descripcion" => array:1 [
              "es" => "Retroceso de la línea de implantación frontotemporal en una mujer de 58 años. Se observa la pérdida completa del pelo de la ceja camuflada por la paciente mediante maquillaje."
            ]
          ]
        ]
        "autores" => array:1 [
          0 => array:2 [
            "autoresLista" => "D Moreno-Ramírez, L Ferrándiz, FM Camacho"
            "autores" => array:3 [
              0 => array:2 [
                "Iniciales" => "D"
                "apellidos" => "Moreno-Ramírez"
              ]
              1 => array:2 [
                "Iniciales" => "L"
                "apellidos" => "Ferrándiz"
              ]
              2 => array:2 [
                "Iniciales" => "FM"
                "apellidos" => "Camacho"
              ]
            ]
          ]
        ]
      ]
      "idiomaDefecto" => "es"
      "Traduccion" => array:1 [
        "en" => array:9 [
          "pii" => "S1578219007705243"
          "doi" => "10.1016/S1578-2190(07)70524-3"
          "estado" => "S300"
          "subdocumento" => ""
          "abierto" => array:3 [
            "ES" => true
            "ES2" => true
            "LATM" => true
          ]
          "gratuito" => true
          "lecturas" => array:1 [
            "total" => 0
          ]
          "idiomaDefecto" => "en"
          "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219007705243?idApp=UINPBA000044"
        ]
      ]
      "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/13110361?idApp=UINPBA000044"
      "url" => "/00017310/0000009800000009/v0_201507151109/13110361/v0_201507151109/es/main.assets"
    ]
  ]
  "itemSiguiente" => array:19 [
    "pii" => "S1578219007705255"
    "issn" => "15782190"
    "doi" => "10.1016/S1578-2190(07)70525-5"
    "estado" => "S300"
    "fechaPublicacion" => "2007-11-01"
    "aid" => "70525"
    "copyright" => "Academia Española de Dermatología y Venereología and Elsevier España, S.L."
    "documento" => "article"
    "crossmark" => 0
    "subdocumento" => "fla"
    "cita" => "Actas Dermosifiliogr. 2007;98:603-10"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:2 [
      "total" => 7372
      "formatos" => array:3 [
        "EPUB" => 32
        "HTML" => 2749
        "PDF" => 4591
      ]
    ]
    "en" => array:11 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">Original articles</span>"
      "titulo" => "Repigmentation of Gray Hair After Thyroid Hormone Treatment"
      "tienePdf" => "en"
      "tieneTextoCompleto" => 0
      "tieneResumen" => array:2 [
        0 => "en"
        1 => "es"
      ]
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "603"
          "paginaFinal" => "610"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "es" => array:1 [
          "titulo" => "Repigmentaci&#243;n del Pelo Canoso Tras Tratamiento Con Hormona Tiroidea"
        ]
      ]
      "contieneResumen" => array:2 [
        "en" => true
        "es" => true
      ]
      "contienePdf" => array:1 [
        "en" => true
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "P&#46; Redondo, M&#46; Guzm&#225;n, M&#46; Marquina, M&#46; Pretel, L&#46; Aguado, P&#46; Lloret, A&#46; Gorrochategui"
          "autores" => array:7 [
            0 => array:2 [
              "nombre" => "P&#46;"
              "apellidos" => "Redondo"
            ]
            1 => array:2 [
              "nombre" => "M&#46;"
              "apellidos" => "Guzm&#225;n"
            ]
            2 => array:2 [
              "nombre" => "M&#46;"
              "apellidos" => "Marquina"
            ]
            3 => array:2 [
              "nombre" => "M&#46;"
              "apellidos" => "Pretel"
            ]
            4 => array:2 [
              "nombre" => "L&#46;"
              "apellidos" => "Aguado"
            ]
            5 => array:2 [
              "nombre" => "P&#46;"
              "apellidos" => "Lloret"
            ]
            6 => array:2 [
              "nombre" => "A&#46;"
              "apellidos" => "Gorrochategui"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "en"
    "Traduccion" => array:1 [
      "es" => array:8 [
        "pii" => "13110362"
        "estado" => "S300"
        "subdocumento" => ""
        "abierto" => array:3 [
          "ES" => true
          "ES2" => true
          "LATM" => true
        ]
        "gratuito" => true
        "lecturas" => array:1 [
          "total" => 0
        ]
        "idiomaDefecto" => "es"
        "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/13110362?idApp=UINPBA000044"
      ]
    ]
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219007705255?idApp=UINPBA000044"
    "url" => "/15782190/0000009800000009/v1_201304241420/S1578219007705255/v1_201304241420/en/main.assets"
  ]
  "itemAnterior" => array:19 [
    "pii" => "S1578219007705231"
    "issn" => "15782190"
    "doi" => "10.1016/S1578-2190(07)70523-1"
    "estado" => "S300"
    "fechaPublicacion" => "2007-11-01"
    "aid" => "70523"
    "copyright" => "Academia Espa&#241;ola de Dermatolog&#237;a y Venereolog&#237;a and Elsevier Espa&#241;a&#44; S&#46;L&#46;"
    "documento" => "article"
    "crossmark" => 0
    "subdocumento" => "rev"
    "cita" => "Actas Dermosifiliogr. 2007;98:583-93"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:2 [
      "total" => 2975
      "formatos" => array:3 [
        "EPUB" => 51
        "HTML" => 1790
        "PDF" => 1134
      ]
    ]
    "en" => array:11 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">Review article</span>"
      "titulo" => "Cutaneous squamous cell carcicoma and human papillomavirus"
      "tienePdf" => "en"
      "tieneTextoCompleto" => 0
      "tieneResumen" => array:2 [
        0 => "en"
        1 => "es"
      ]
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "583"
          "paginaFinal" => "593"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "es" => array:1 [
          "titulo" => "Carcinoma Espinocelular Cut&#225;neo y Papilomavirus &#40;VPH&#41;"
        ]
      ]
      "contieneResumen" => array:2 [
        "en" => true
        "es" => true
      ]
      "contienePdf" => array:1 [
        "en" => true
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "R&#46; Corbal&#225;n-V&#233;lez, J&#46;A&#46; Ruiz-Maci&#225;, C&#46; Brufau, F&#46;J&#46; Carapeto"
          "autores" => array:4 [
            0 => array:2 [
              "nombre" => "R&#46;"
              "apellidos" => "Corbal&#225;n-V&#233;lez"
            ]
            1 => array:2 [
              "nombre" => "J&#46;A&#46;"
              "apellidos" => "Ruiz-Maci&#225;"
            ]
            2 => array:2 [
              "nombre" => "C&#46;"
              "apellidos" => "Brufau"
            ]
            3 => array:2 [
              "nombre" => "F&#46;J&#46;"
              "apellidos" => "Carapeto"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "en"
    "Traduccion" => array:1 [
      "es" => array:8 [
        "pii" => "13110360"
        "estado" => "S300"
        "subdocumento" => ""
        "abierto" => array:3 [
          "ES" => true
          "ES2" => true
          "LATM" => true
        ]
        "gratuito" => true
        "lecturas" => array:1 [
          "total" => 0
        ]
        "idiomaDefecto" => "es"
        "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/13110360?idApp=UINPBA000044"
      ]
    ]
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219007705231?idApp=UINPBA000044"
    "url" => "/15782190/0000009800000009/v1_201304241420/S1578219007705231/v1_201304241420/en/main.assets"
  ]
  "en" => array:13 [
    "idiomaDefecto" => true
    "cabecera" => "<span class="elsevierStyleTextfn">Practical dermatology</span>"
    "titulo" => "Diagnostic and Therapeutic Assessment of Frontal Fibrosing Alopecia"
    "tieneTextoCompleto" => 0
    "paginas" => array:1 [
      0 => array:2 [
        "paginaInicial" => "594"
        "paginaFinal" => "602"
      ]
    ]
    "autores" => array:1 [
      0 => array:4 [
        "autoresLista" => "D&#46; Moreno-Ram&#237;rez, L&#46; Ferr&#225;ndiz, F&#46;M&#46; Camacho"
        "autores" => array:3 [
          0 => array:4 [
            "nombre" => "D&#46;"
            "apellidos" => "Moreno-Ram&#237;rez"
            "email" => array:1 [
              0 => "dmoreno&#64;e-derma&#46;org"
            ]
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">¿</span>"
                "identificador" => "cor1"
              ]
            ]
          ]
          1 => array:2 [
            "nombre" => "L&#46;"
            "apellidos" => "Ferr&#225;ndiz"
          ]
          2 => array:2 [
            "nombre" => "F&#46;M&#46;"
            "apellidos" => "Camacho"
          ]
        ]
        "afiliaciones" => array:1 [
          0 => array:1 [
            "entidad" => "Departamento de Dermatolog&#237;a M&#233;dico-Quir&#250;rgica y Venereolog&#237;a&#46; Hospital Universitario Virgen Macarena&#44; Sevilla&#44; Spain"
          ]
        ]
        "correspondencia" => array:1 [
          0 => array:3 [
            "identificador" => "cor1"
            "etiqueta" => "&#8270;"
            "correspondencia" => "Correspondence&#58; Departamento de Dermatolog&#237;a M&#233;dico-Quir&#250;rgica y Venereolog&#237;a&#46; Hospital Universitario Virgen Macarena&#46; Sevilla&#46; Avda&#46; Dr&#46; Fedriani&#44; s&#47;n 41009 Sevilla&#46; Spain&#46;"
          ]
        ]
      ]
    ]
    "titulosAlternativos" => array:1 [
      "es" => array:1 [
        "titulo" => "Alopecia Frontal Fibrosante&#46; Valoraci&#243;n Diagn&#243;stica y Terap&#233;utica"
      ]
    ]
    "pdfFichero" => "main.pdf"
    "tienePdf" => true
    "PalabrasClave" => array:2 [
      "en" => array:1 [
        0 => array:4 [
          "clase" => "keyword"
          "titulo" => "Key words"
          "identificador" => "xpalclavsec84036"
          "palabras" => array:4 [
            0 => "frontal fibrosing alopecia"
            1 => "postmenopause"
            2 => "postmenopausal"
            3 => "scarring alopecia"
          ]
        ]
      ]
      "es" => array:1 [
        0 => array:4 [
          "clase" => "keyword"
          "titulo" => "Palabras clave"
          "identificador" => "xpalclavsec84035"
          "palabras" => array:4 [
            0 => "alopecia frontal fibrosante"
            1 => "posmenopausia"
            2 => "posmenop&#225;usica"
            3 => "alopecia cicatricial"
          ]
        ]
      ]
    ]
    "tieneResumen" => true
    "resumen" => array:2 [
      "en" => array:2 [
        "titulo" => "Abstract"
        "resumen" => "<p class="elsevierStyleSimplePara elsevierViewall">Frontal fibrosing alopecia is a clinical entity characterized by recession of the frontotemporal hairline in middle-aged and older women&#46; Since it was first described in 1994&#44; more than 100 cases have been reported describing other clinical manifestations such as eyebrow and axillary alopecia&#44; and perifollicular inflammation that help in the diagnosis of the disease and the differential diagnosis with other scarring alopecias&#46; Histopathology reveals an inflammatory infiltrate and perifollicular lamellar fibrosis&#46; Although numerous therapeutic options have been tested&#44; including corticosteroids&#44; finasteride&#44; and minoxidil&#44; none have shown clear benefits in terms of halting the progression of the alopecia&#46;</p>"
      ]
      "es" => array:2 [
        "titulo" => "Resumen"
        "resumen" => "<p class="elsevierStyleSimplePara elsevierViewall">La alopecia frontal fibrosante es una entidad cl&#237;nica caracterizada por la recesi&#243;n de la l&#237;nea de implantaci&#243;n frontotemporal de aparici&#243;n en mujeres de edad media y avanzada&#46; Desde su descripci&#243;n en 1994&#44; se han publicado m&#225;s de un centenar de casos de pacientes con este cuadro&#44; describi&#233;ndose otras manifestaciones como alopecia de cejas y axilas&#44; inflamaci&#243;n perifolicular&#44; etc&#46;&#44; que ayudan al diagn&#243;stico cl&#237;nico de esta entidad y a su diagn&#243;stico diferencial con otras alopecias cicatriciales&#46; Histopatol&#243;gicamente presenta un infiltrado inflamatorio y fibrosis lamelar perifolicular&#46; Desde el punto de vista terap&#233;utico&#44; se han probado numerosas opciones como corticosteroides&#44; finasterida&#44; minoxidil&#44; etc&#46;&#44; sin que ninguna haya demostrado un beneficio claro en la detenci&#243;n de la progresi&#243;n de la alopecia&#46;</p>"
      ]
    ]
    "bibliografia" => array:2 [
      "titulo" => "References"
      "seccion" => array:1 [
        0 => array:1 [
          "bibliografiaReferencia" => array:8 [
            0 => array:3 [
              "identificador" => "bib1"
              "etiqueta" => "1&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Postmenopausal frontal fibrosing alopecia&#46; Scarring alopecia in a pattern distribution"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "S&#46; Kossard"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Arch Dermatol"
                        "fecha" => "1994"
                        "volumen" => "130"
                        "paginaInicial" => "770"
                        "paginaFinal" => "774"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8002649"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            1 => array:3 [
              "identificador" => "bib2"
              "etiqueta" => "2&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Postmenopausal frontal fibrosing alopecia&#58; a variant of lichen planopilaris"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "S&#46; Kossard"
                            1 => "M&#46;S&#46; Lee"
                            2 => "B&#46; Wilkinson"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "J Am Acad Dermatol"
                        "fecha" => "1997"
                        "volumen" => "36"
                        "paginaInicial" => "59"
                        "paginaFinal" => "66"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8996262"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            2 => array:3 [
              "identificador" => "bib3"
              "etiqueta" => "3&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Postmenopausal frontal fibrosing alopecia"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "E&#46; Naz"
                            1 => "C&#46; Vidaurrazaga"
                            2 => "N&#46; Hern&#225;ndez-Cano"
                            3 => "P&#46; Herranz"
                            4 => "M&#46; Mayor"
                            5 => "M&#46; Hervella"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Clin Exp Dermatol"
                        "fecha" => "2003"
                        "volumen" => "28"
                        "paginaInicial" => "25"
                        "paginaFinal" => "27"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12558623"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            3 => array:3 [
              "identificador" => "bib4"
              "etiqueta" => "4&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Alop&#233;cie fibrosante frontale post-m&#233;nopausique&#58; 20 cas"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "V&#46; Vaisse"
                            1 => "B&#46; Matard"
                            2 => "P&#46; Assouly"
                            3 => "C&#46; Jouannique"
                            4 => "P&#46; Reygagne"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Ann Dermatol Venereol"
                        "fecha" => "2003"
                        "volumen" => "130"
                        "paginaInicial" => "607"
                        "paginaFinal" => "610"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/13679696"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            4 => array:3 [
              "identificador" => "bib5"
              "etiqueta" => "5&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Frontal fibrosing alopecia&#58; a survey in 16 patients"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "D&#46; Moreno-Ram&#237;rez"
                            1 => "F&#46; Camacho Mart&#237;nez"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1111/j.1468-3083.2005.01291.x"
                      "Revista" => array:6 [
                        "tituloSerie" => "J Eur Acad Dermatol Venereol"
                        "fecha" => "2005"
                        "volumen" => "19"
                        "paginaInicial" => "700"
                        "paginaFinal" => "705"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16268874"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            5 => array:3 [
              "identificador" => "bib6"
              "etiqueta" => "6&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Frontal fibrosing alopecia in postmenopausal women"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "A&#46; Tosti"
                            1 => "B&#46;M&#46; Piraccini"
                            2 => "M&#46; Iorizzo"
                            3 => "C&#46; Misciali"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1016/j.jaad.2004.05.014"
                      "Revista" => array:6 [
                        "tituloSerie" => "J Am Acad Dermatol"
                        "fecha" => "2005"
                        "volumen" => "52"
                        "paginaInicial" => "55"
                        "paginaFinal" => "60"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15627081"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            6 => array:3 [
              "identificador" => "bib7"
              "etiqueta" => "7&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Frontal fibrosing alopecia versus lichen planopilaris&#58; a clinicopathological study"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "E&#46; Poblet"
                            1 => "F&#46; Jim&#233;nez"
                            2 => "A&#46; Pascual"
                            3 => "E&#46; Pique"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1111/j.1365-4632.2006.02507.x"
                      "Revista" => array:6 [
                        "tituloSerie" => "Int J Dermatol"
                        "fecha" => "2006"
                        "volumen" => "45"
                        "paginaInicial" => "375"
                        "paginaFinal" => "380"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16650161"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            7 => array:3 [
              "identificador" => "bib8"
              "etiqueta" => "8&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Alopecia frontal fibrosante postmenop&#225;usica&#58; una variante de liquen plano folicular de localizaci&#243;n peculiar"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "P&#46; Escalonilla"
                            1 => "M&#46;L&#46; Soriano"
                            2 => "R&#46; Grillo"
                            3 => "C&#46; Fari&#241;a"
                            4 => "L&#46; Mart&#237;n"
                            5 => "L&#46; Requena"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Actas Dermosifiliogr"
                        "fecha" => "1999"
                        "volumen" => "90"
                        "paginaInicial" => "185"
                        "paginaFinal" => "195"
                      ]
                    ]
                  ]
                ]
              ]
            ]
          ]
        ]
      ]
    ]
  ]
  "idiomaDefecto" => "en"
  "url" => "/15782190/0000009800000009/v1_201304241420/S1578219007705243/v1_201304241420/en/main.assets"
  "Apartado" => array:4 [
    "identificador" => "6151"
    "tipo" => "SECCION"
    "en" => array:2 [
      "titulo" => "Practical Dermatology"
      "idiomaDefecto" => true
    ]
    "idiomaDefecto" => "en"
  ]
  "PDF" => "https://static.elsevier.es/multimedia/15782190/0000009800000009/v1_201304241420/S1578219007705243/v1_201304241420/en/main.pdf?idApp=UINPBA000044&text.app=https://actasdermo.org/"
  "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219007705243?idApp=UINPBA000044"
]
Compartir
Información de la revista
Vol. 98. Núm. 9.
Páginas 594-602 (noviembre 2007)
Vol. 98. Núm. 9.
Páginas 594-602 (noviembre 2007)
Practical dermatology
Acceso a texto completo
Diagnostic and Therapeutic Assessment of Frontal Fibrosing Alopecia
Alopecia Frontal Fibrosante. Valoración Diagnóstica y Terapéutica
Visitas
12240
D. Moreno-Ramírez
Autor para correspondencia
dmoreno@e-derma.org

Correspondence: Departamento de Dermatología Médico-Quirúrgica y Venereología. Hospital Universitario Virgen Macarena. Sevilla. Avda. Dr. Fedriani, s/n 41009 Sevilla. Spain.
, L. Ferrándiz, F.M. Camacho
Departamento de Dermatología Médico-Quirúrgica y Venereología. Hospital Universitario Virgen Macarena, Sevilla, Spain
Este artículo ha recibido
Información del artículo
Abstract

Frontal fibrosing alopecia is a clinical entity characterized by recession of the frontotemporal hairline in middle-aged and older women. Since it was first described in 1994, more than 100 cases have been reported describing other clinical manifestations such as eyebrow and axillary alopecia, and perifollicular inflammation that help in the diagnosis of the disease and the differential diagnosis with other scarring alopecias. Histopathology reveals an inflammatory infiltrate and perifollicular lamellar fibrosis. Although numerous therapeutic options have been tested, including corticosteroids, finasteride, and minoxidil, none have shown clear benefits in terms of halting the progression of the alopecia.

Key words:
frontal fibrosing alopecia
postmenopause
postmenopausal
scarring alopecia
Resumen

La alopecia frontal fibrosante es una entidad clínica caracterizada por la recesión de la línea de implantación frontotemporal de aparición en mujeres de edad media y avanzada. Desde su descripción en 1994, se han publicado más de un centenar de casos de pacientes con este cuadro, describiéndose otras manifestaciones como alopecia de cejas y axilas, inflamación perifolicular, etc., que ayudan al diagnóstico clínico de esta entidad y a su diagnóstico diferencial con otras alopecias cicatriciales. Histopatológicamente presenta un infiltrado inflamatorio y fibrosis lamelar perifolicular. Desde el punto de vista terapéutico, se han probado numerosas opciones como corticosteroides, finasterida, minoxidil, etc., sin que ninguna haya demostrado un beneficio claro en la detención de la progresión de la alopecia.

Palabras clave:
alopecia frontal fibrosante
posmenopausia
posmenopáusica
alopecia cicatricial
El Texto completo está disponible en PDF
References
[1.]
S. Kossard.
Postmenopausal frontal fibrosing alopecia. Scarring alopecia in a pattern distribution.
Arch Dermatol, 130 (1994), pp. 770-774
[2.]
S. Kossard, M.S. Lee, B. Wilkinson.
Postmenopausal frontal fibrosing alopecia: a variant of lichen planopilaris.
J Am Acad Dermatol, 36 (1997), pp. 59-66
[3.]
E. Naz, C. Vidaurrazaga, N. Hernández-Cano, P. Herranz, M. Mayor, M. Hervella, et al.
Postmenopausal frontal fibrosing alopecia.
Clin Exp Dermatol, 28 (2003), pp. 25-27
[4.]
V. Vaisse, B. Matard, P. Assouly, C. Jouannique, P. Reygagne.
Alopécie fibrosante frontale post-ménopausique: 20 cas.
Ann Dermatol Venereol, 130 (2003), pp. 607-610
[5.]
D. Moreno-Ramírez, F. Camacho Martínez.
Frontal fibrosing alopecia: a survey in 16 patients.
J Eur Acad Dermatol Venereol, 19 (2005), pp. 700-705
[6.]
A. Tosti, B.M. Piraccini, M. Iorizzo, C. Misciali.
Frontal fibrosing alopecia in postmenopausal women.
J Am Acad Dermatol, 52 (2005), pp. 55-60
[7.]
E. Poblet, F. Jiménez, A. Pascual, E. Pique.
Frontal fibrosing alopecia versus lichen planopilaris: a clinicopathological study.
Int J Dermatol, 45 (2006), pp. 375-380
[8.]
P. Escalonilla, M.L. Soriano, R. Grillo, C. Fariña, L. Martín, L. Requena, et al.
Alopecia frontal fibrosante postmenopáusica: una variante de liquen plano folicular de localización peculiar.
Actas Dermosifiliogr, 90 (1999), pp. 185-195
Copyright © 2007. Academia Española de Dermatología y Venereología and Elsevier España, S.L.
Descargar PDF
Idiomas
Actas Dermo-Sifiliográficas
Opciones de artículo
Herramientas
es en

¿Es usted profesional sanitario apto para prescribir o dispensar medicamentos?

Are you a health professional able to prescribe or dispense drugs?