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Vol. 101. Issue 3.
Pages 230-234 (April 2010)
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Vol. 101. Issue 3.
Pages 230-234 (April 2010)
Original Article
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Psoriasis Affects Individuals of African Descent and White Brazilians Similarly
La psoriasis afecta de forma similar a los pacientes brasileños de ascendencia africana y caucásica
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C. Porto Ferreiraa,b,
Corresponding author
drcassioferreira@yahoo.com.br

Corresponding author.
, C.J. Martinsc, P.R. Issac, R. de Vasconcellos Carvalhaes de Oliveiraa,b, A.M. Da-Cruza,d
a Laboratório de Interdisciplinar de Pesquisas Médicas, Instituto Oswaldo Cruz/FIOCRUZ, Rio de Janeiro, Brazil
b Instituto de Pesquisa Clínica Evandro Chagas/FIOCRUZ, Rio de Janeiro, Brazil
c Serviço de Dermatologia, Hospital Universitário Gaffré e Guinle, Universidade Federal do Estado do Rio de Janeiro (UNIRIO), Brazil
d Faculdade de Ciências Médicas, Universidade do Estado do Rio de Janeiro, Brazil
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Article information
Abstract
Introduction

Cultural, socio-demographic and environmental factors such as tropical climate and exposure to sun could have an impact on the incidence or clinical course of psoriasis. Here we describe the main clinical aspects of psoriasis in Brazilian patients and also investigate whether any particular feature can distinguish the disease occurring in Brazil from that occurring in other countries.

Material and methods

We recorded the clinical features of 151 psoriasis patients seen in a Brazilian public dermatological care unit between 2006 and 2008.

Results

Males and females were similarly affected. The reported races were as follows: whites, 47 cases (41.6%), interracial individuals (mixed race), 42 cases (37.2%) and blacks, 24 cases (21.2%). Chronic plaque-type psoriasis was the most prevalent clinical form (110 cases, 72.8%) followed by palm and sole involvement (21 cases, 13.9%).

Conclusions

We demonstrated that psoriasis in these Brazilian subjects was similar to that observed in subjects from other countries, but interracial and black populations were affected as much as whites. Considering the high rate of interracial populations among Brazilians we cannot exclude the possibility that Afro-descendants may have inherited Caucasian genes associated with psoriasis. Poor socio-economic conditions of Afro-descendants can limit their possibilities of receiving adequate treatments, impairing their health-related quality of life.

Keywords:
Psoriasis
Clinical features
Afro-descendants
Brazilian population
Blacks
Resumen
Introducción

Los factores culturales, sociodemográficos y ambientales tales como el clima tropical o la exposición solar pueden tener un impacto en la incidencia o el curso clínico de la psoriasis. En este artículo describimos los principales aspectos clínicos de la psoriasis en pacientes brasileños e investigamos si existe alguna característica que permita distinguir la enfermedad que ocurre en Brasil de la que se encuentra en otros países.

Material y métodos

Se recogieron las características clínicas de 151 pacientes con psoriasis evaluados en un centro dermatológico público de Brasil entre 2006 y 2008.

Resultados

Los hombres y las mujeres estaban afectados de forma similar. La frecuencia de afectación según la raza era la siguiente: blancos 47 casos (41,6%), mestizos 42 casos (37,2%) y negros 24 casos (21,2%). Las formas clínicas más prevalentes fueron la psoriasis crónica en placas (110 casos, 72,8%) seguida de la psoriasis palmoplantar (21 casos, 13,9%).

Conclusiones

Demostramos que la psoriasis en estos sujetos brasileños es similar a la que se observa en sujetos de otros países, pero los mestizos y los negros están afectados tanto como los blancos. Teniendo en cuenta la elevada proporción de población mestiza entre los brasileños, no podemos descartar la posibilidad de que los descendientes africanos hayan podido heredar los genes caucásicos asociados a la psoriasis. Las pobres condiciones socioeconómicas de los descendientes africanos pueden limitar sus posibilidades para recibir tratamientos adecuados, lo que altera su calidad de vida.

Palabras clave:
Psoriasis
Características clínicas
Afrodescendientes
Población brasileña
Negros
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References
[1.]
E. Christophers.
Psoriasis-epidemiology and clinical spectrum.
Clin Exp Dermatol, 26 (2001), pp. 314-320
[2.]
J.E. Gudjonsson, J.T. Elder.
Psoriasis: epidemiology.
Clin Dermatol, 25 (2007), pp. 535-546
[3.]
M. Lebwohl.
Psoriasis.
Lancet, 361 (2003), pp. 1197-1204
[4.]
C.E.M. Griffiths, J.N.W.N. Barker.
Pathogenesis and clinical features of psoriasis.
[5.]
R. Sabat, S. Philip, C. Höflich, S. Kreutzer, E. Wallace, K. Asadullah, et al.
Immunopathogenesis of psoriasis.
Exp Dermatol, 16 (2007), pp. 779-798
[6.]
M.A. Lowes, A.M. Bowcock, J.G. Krueger.
Pathogenesis and therapy of psoriasis.
Nature, 445 (2007), pp. 866-873
[7.]
F. Sampogna, P. Gisondi, C.F. Melchi, P. Amerio, G. Girolomoni, D. Abeni, et al.
Prevalence of symptoms experienced by patients with different clinical types of psoriasis.
Br J Dermatol, 151 (2004), pp. 594-599
[8.]
F.M. Aslanian, F.F. Lisboa, A. Iwamoto, S.C. Carneiro.
Clinical and epidemiological evaluation of psoriasis: clinical variants and articular manifestations.
J Eur Acad Dermatol Venereol, 19 (2005), pp. 141-142
[9.]
R.D. Azulay, C. Salvatti, P.C. Rodrigues.
Estudo comparativo da psoríase em duas instituições dermatológicas no período de 11 anos.
An Bras Dermatol, 50 (1975), pp. 33-47
[10.]
S.R. Feldman, G.G. Krueger.
Psoriasis assessment tools in clinical trials.
Ann Rheum Dis, 64 (2005), pp. ii65-ii68
[11.]
A.B. Gottlieb, U. Chaudhari, D.G. Baker, M. Perate, L.T. Dooley.
The National Psoriasis Foundation Psoriasis Score (NPF-PS) System versus the Psoriasis Area Severity Index (PASI) and Physician's Global Assessment (PGA): a comparison.
J Drugs Dermatol, 2 (2003), pp. 260-266
[12.]
A. García-Diez, C.F. Foraster, F.V. Sebastián, L.L. Tudela, X.B. Llach, G.S. Fernández.
What characterizes the severity of psoriasis? Results from an epidemiological study of over 3,300 patients in the Iberian region.
Dermatology, 216 (2008), pp. 137-151
[13.]
L. Puiga, X. Bordas, J.M. Carrascosa, E. Daudén, C. Ferrándiz, J.M. Hernanz, et al.
Documento de consenso sobre la evaluación y el tratamiento de la psoriasis moderada/grave del Grupo Español de Psoriasis de la Academia Española de Dermatología y Venereología.
Actas Dermosifiliogr, 100 (2009), pp. 277-286
[14.]
R.G. Langley, C.N. Ellis.
Evaluating psoriasis with Psoriasis Area and Severity index, Psoriasis Global Assessment, and Lattice System Physician's Global Assessment.
J Am Acad Dermatol, 51 (2004), pp. 563-569
[15.]
J. Berth-Jones, K. Grotzinger, C. Rainville, B. Pham, J. Huang, S. Daly, et al.
A study examining inter- and intrarater reliability of three scales for measuring severity of psoriasis: Psoriasis Area and Severity Index, Physician's Global Assessment and Lattice System Physician's Global Assessment.
Br J Dermatol, 155 (2006), pp. 707-713
[16.]
D. Ashcroft, A.L. Wan Po, H.C. Williams, C.E. Griffiths.
Clinical measures of disease severity and outcome in psoriasis: a critical appraisal of their quality.
Br J Dermatol, 141 (1999), pp. 185-191
[17.]
P.C. Van der Kerkhof.
The psoriasis area and severity index and alternative approaches for the assessment of severity: persisting areas of confusion.
Br J Dermatol, 137 (1997), pp. 661-662
[18.]
Puig L. ¿Es realmente útil el PASI como parámetro de medida de severidad en la psoriasis? [Accessed on July 14, 2009]. Available from: http://www.aedv.es/grupo_psoriasis/archivo/utilidad%20PASI.pdf.
[19.]
J.M. Gelfand, R.S. Stern, T. Nijsten, S.R. Feldman, J. Thomas, J. Kist, et al.
The prevalence of psoriasis in African Americans: results from a population-based.
J Am Acad Dermatol, 52 (2005), pp. 23-26
[20.]
I.A. Trujillo, M.A.D. Garci´a, O.T. Gemeil, F.T. Barbosa, L.F. Lincheta, M.P. Pérez Hernández.
Psoriasis vulgar. Estudio descriptivo de 200 pacientes.
Rev Cubana Med, 41 (2002), pp. 12-15
[21.]
M. Ozawa, K. Ferenczi, T. Kikuchi, I. Cardinale, L.M. Austin, T.R. Coven, et al.
312-nanometer ultraviolet B light (narrow-band UVB) induces apoptosis of T cells within psoriatic lesions.
J Exp Med, 189 (1999), pp. 711-718
[22.]
C. González, L.A. Castro, G. de la Cruz, C.M. Arenas, A. Beltrán, A.M. Santos.
Caracterización epidemiológica de la psoriasis en el Hospital Militar Central.
Rev Asoc Col Dermatol, 17 (2009), pp. 11-17
[23.]
Instituto Brasileiro de Geografia e Estatística, IBGE, Ministério do Planejamento Orcamento e Gestao, Brazil [Accessed on December 21, 2008]. Available from: http://www.ibge.gov.br/home/estatistica/populacao/censo2000/populacao/tabela_brasil.shtm.
[24.]
M.R. Namazi.
Why is psoriasis uncommon in Africans?.
The influence of dietary factors on the expression of psoriasis Int J Dermatol, 43 (2004), pp. 391-392
[25.]
R. Bonfiglioli, R.A. Conde, P.D. Sampaio-Barros, P. Louzada-Junior, E.A. Donadi, M.B. Bertolo.
Frequency of HLA-B27 alleles in Brazilian patients with psoriatic arthritis.
Clin Rheumatol, 27 (2008), pp. 709-712
[26.]
A.C. Green.
Australian aborigines and psoriasis.
Australas J Dermatol, 25 (1984), pp. 18-24
[27.]
G. Lomholt.
Prevalence of skin diseases in a population: A census study from the Faroe Islands.
Dan Med Bull, 11 (1964), pp. 1-7
[28.]
A.R. Verhagen, J.W. Koten.
Psoriasis in Kenya.
Arch Dermatol, 96 (1967), pp. 39-41
[29.]
S.Y. Yip.
The prevalence of psoriasis in the Mongoloid race.
J Am Acad Dermatol, 10 (1984), pp. 965-968
[30.]
A. Plunkett, R. Marks.
A review of the epidemiology of psoriasis vulgaris in the community.
Australas J Dermatol, 39 (1998), pp. 225-232
[31.]
A.M. Bowcock.
The genetics of psoriasis and autoimmunity.
Annu Rev Genomics Hum Genet, 6 (2005), pp. 93-122
[32.]
L.M. Bell, R. Sedlack, C.M. Beard, H.O. Perry, C.J. Michet, L.T. Kurland.
Incidence of psoriasis in Rochester, Minn, 1980-1983.
Arch Dermatol, 127 (1991), pp. 1184-1187
[33.]
E. Farber, M. Nail.
The natural history of psoriasis in 5,600 patients.
Dermatologica, 148 (1974), pp. 1-18
[34.]
C. Ferrándiz, X. Bordas, V. García-Patos, S. Puig, R. Pujol, A. Smandía, et al.
Prevalence of psoriasis in Spain (Epiderma Project: phase I).
J Eur Acad Dermatol Venereol, 15 (2001), pp. 20-23
[35.]
S.P. Raychaudhuri, E.M. Farber.
The prevalence of psoriasis in the world.
J Eur Acad Dermatol Venereol, 15 (2001), pp. 16-17
[36.]
J.M. Gelfand, R. Weinstein, S.B. Porter, A.L. Neimann, J.A. Berlin, D.J. Margolis.
Prevalence and treatment of psoriasis in the United Kingdom. A population-based study.
Arch Dermatol, 141 (2005), pp. 1537-1541
[37.]
S.T. Hartshorne.
Dermatological disorders in Johannesburg, South Africa.
Clin Exp Dermatol, 28 (2003), pp. 661-665
[38.]
R. Saraceno, R. Mannheimer, S. Chimenti.
Regional distribution of psoriasis in Italy.
J Eur Acad Dermatol Venereol, 22 (2008), pp. 324-329
[39.]
Conselho Nacional de Secretários de Saúde Legislacão do SUS. Brazil [Accessed on July 28, 2009]. Available from: http://bvsms.saude.gov.br/bvs/publicacoes/progestores/leg_sus.pdf.
[40.]
L.H. Arruda, A.P. de Moraes.
The impact of psoriasis on quality of life.
Br J Dermatol, 144 (2001), pp. 33-36
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