array:24 [
  "pii" => "S1578219018303639"
  "issn" => "15782190"
  "doi" => "10.1016/j.adengl.2018.10.009"
  "estado" => "S300"
  "fechaPublicacion" => "2018-12-01"
  "aid" => "1930"
  "copyright" => "Elsevier España, S.L.U. and AEDV"
  "copyrightAnyo" => "2018"
  "documento" => "simple-article"
  "crossmark" => 1
  "subdocumento" => "crp"
  "cita" => "Actas Dermosifiliogr. 2018;109:933-4"
  "abierto" => array:3 [
    "ES" => true
    "ES2" => true
    "LATM" => true
  ]
  "gratuito" => true
  "lecturas" => array:1 [
    "total" => 0
  ]
  "Traduccion" => array:1 [
    "es" => array:19 [
      "pii" => "S0001731018300929"
      "issn" => "00017310"
      "doi" => "10.1016/j.ad.2017.11.017"
      "estado" => "S300"
      "fechaPublicacion" => "2018-12-01"
      "aid" => "1930"
      "copyright" => "AEDV"
      "documento" => "simple-article"
      "crossmark" => 1
      "subdocumento" => "crp"
      "cita" => "Actas Dermosifiliogr. 2018;109:933-4"
      "abierto" => array:3 [
        "ES" => true
        "ES2" => true
        "LATM" => true
      ]
      "gratuito" => true
      "lecturas" => array:2 [
        "total" => 138
        "formatos" => array:2 [
          "HTML" => 105
          "PDF" => 33
        ]
      ]
      "es" => array:11 [
        "idiomaDefecto" => true
        "cabecera" => "<span class="elsevierStyleTextfn">Carta cient&#237;fico-cl&#237;nica</span>"
        "titulo" => "Tres casos de sarcoidosis del cuero cabelludo con alopecia"
        "tienePdf" => "es"
        "tieneTextoCompleto" => "es"
        "paginas" => array:1 [
          0 => array:2 [
            "paginaInicial" => "933"
            "paginaFinal" => "934"
          ]
        ]
        "titulosAlternativos" => array:1 [
          "en" => array:1 [
            "titulo" => "Three Cases of Scalp Sarcoidosis with Alopecia"
          ]
        ]
        "contieneTextoCompleto" => array:1 [
          "es" => true
        ]
        "contienePdf" => array:1 [
          "es" => true
        ]
        "resumenGrafico" => array:2 [
          "original" => 0
          "multimedia" => array:7 [
            "identificador" => "fig0005"
            "etiqueta" => "Figura 1"
            "tipo" => "MULTIMEDIAFIGURA"
            "mostrarFloat" => true
            "mostrarDisplay" => false
            "figura" => array:1 [
              0 => array:4 [
                "imagen" => "gr1.jpeg"
                "Alto" => 879
                "Ancho" => 1750
                "Tamanyo" => 439642
              ]
            ]
            "descripcion" => array:1 [
              "es" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Caracter&#237;sticas cl&#237;nicas e histol&#243;gicas de la sarcoidosis del cuero cabelludo &#40;a y b&#58; caso 1&#59; c y d&#58; caso 2&#59; e y f&#58; caso 3&#41;&#46; Tinci&#243;n hematoxilina-eosina&#44; ampliaci&#243;n del original &#215;200&#46;</p>"
            ]
          ]
        ]
        "autores" => array:1 [
          0 => array:2 [
            "autoresLista" => "M&#46; Ishikawa, M&#46; Ohtsuka, T&#46; Yamamoto"
            "autores" => array:3 [
              0 => array:2 [
                "nombre" => "M&#46;"
                "apellidos" => "Ishikawa"
              ]
              1 => array:2 [
                "nombre" => "M&#46;"
                "apellidos" => "Ohtsuka"
              ]
              2 => array:2 [
                "nombre" => "T&#46;"
                "apellidos" => "Yamamoto"
              ]
            ]
          ]
        ]
      ]
      "idiomaDefecto" => "es"
      "Traduccion" => array:1 [
        "en" => array:9 [
          "pii" => "S1578219018303639"
          "doi" => "10.1016/j.adengl.2018.10.009"
          "estado" => "S300"
          "subdocumento" => ""
          "abierto" => array:3 [
            "ES" => true
            "ES2" => true
            "LATM" => true
          ]
          "gratuito" => true
          "lecturas" => array:1 [
            "total" => 0
          ]
          "idiomaDefecto" => "en"
          "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219018303639?idApp=UINPBA000044"
        ]
      ]
      "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0001731018300929?idApp=UINPBA000044"
      "url" => "/00017310/0000010900000010/v1_201812060614/S0001731018300929/v1_201812060614/es/main.assets"
    ]
  ]
  "itemSiguiente" => array:19 [
    "pii" => "S1578219018303573"
    "issn" => "15782190"
    "doi" => "10.1016/j.adengl.2018.10.004"
    "estado" => "S300"
    "fechaPublicacion" => "2018-12-01"
    "aid" => "1974"
    "copyright" => "Elsevier Espa&#241;a&#44; S&#46;L&#46;U&#46; and AEDV"
    "documento" => "simple-article"
    "crossmark" => 1
    "subdocumento" => "crp"
    "cita" => "Actas Dermosifiliogr. 2018;109:934-6"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:1 [
      "total" => 0
    ]
    "en" => array:11 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">Case and Research Letters</span>"
      "titulo" => "Stewart-Bluefarb Syndrome&#58; Case Report and Review of the Literature"
      "tienePdf" => "en"
      "tieneTextoCompleto" => "en"
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "934"
          "paginaFinal" => "936"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "es" => array:1 [
          "titulo" => "S&#237;ndrome de Stewart-Bluefarb&#58; caso cl&#237;nico y revisi&#243;n de la literatura"
        ]
      ]
      "contieneTextoCompleto" => array:1 [
        "en" => true
      ]
      "contienePdf" => array:1 [
        "en" => true
      ]
      "resumenGrafico" => array:2 [
        "original" => 0
        "multimedia" => array:7 [
          "identificador" => "fig0005"
          "etiqueta" => "Figure 1"
          "tipo" => "MULTIMEDIAFIGURA"
          "mostrarFloat" => true
          "mostrarDisplay" => false
          "figura" => array:1 [
            0 => array:4 [
              "imagen" => "gr1.jpeg"
              "Alto" => 1134
              "Ancho" => 850
              "Tamanyo" => 160094
            ]
          ]
          "descripcion" => array:1 [
            "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Image showing raised lesions with perilesional eczema in the anterior pretibial surface and outermost supramalleolar region&#46; An ulcer with perilesional cutaneous hyperpigmentation is visible at the center of the image&#46;</p>"
          ]
        ]
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "V&#46;E&#46; Garc&#237;a Blanco, E&#46; Doiz Art&#225;zcoz, M&#46;C&#46; Galera Mart&#237;nez, M&#46; Rodr&#237;guez Pi&#241;ero"
          "autores" => array:4 [
            0 => array:2 [
              "nombre" => "V&#46;E&#46;"
              "apellidos" => "Garc&#237;a Blanco"
            ]
            1 => array:2 [
              "nombre" => "E&#46;"
              "apellidos" => "Doiz Art&#225;zcoz"
            ]
            2 => array:2 [
              "nombre" => "M&#46;C&#46;"
              "apellidos" => "Galera Mart&#237;nez"
            ]
            3 => array:2 [
              "nombre" => "M&#46;"
              "apellidos" => "Rodr&#237;guez Pi&#241;ero"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "en"
    "Traduccion" => array:1 [
      "es" => array:9 [
        "pii" => "S0001731018302126"
        "doi" => "10.1016/j.ad.2018.03.019"
        "estado" => "S300"
        "subdocumento" => ""
        "abierto" => array:3 [
          "ES" => true
          "ES2" => true
          "LATM" => true
        ]
        "gratuito" => true
        "lecturas" => array:1 [
          "total" => 0
        ]
        "idiomaDefecto" => "es"
        "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0001731018302126?idApp=UINPBA000044"
      ]
    ]
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219018303573?idApp=UINPBA000044"
    "url" => "/15782190/0000010900000010/v1_201812060634/S1578219018303573/v1_201812060634/en/main.assets"
  ]
  "itemAnterior" => array:19 [
    "pii" => "S1578219018303615"
    "issn" => "15782190"
    "doi" => "10.1016/j.adengl.2018.10.007"
    "estado" => "S300"
    "fechaPublicacion" => "2018-12-01"
    "aid" => "1889"
    "copyright" => "Elsevier Espa&#241;a&#44; S&#46;L&#46;U&#46; and AEDV"
    "documento" => "simple-article"
    "crossmark" => 1
    "subdocumento" => "crp"
    "cita" => "Actas Dermosifiliogr. 2018;109:929-32"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:2 [
      "total" => 8
      "formatos" => array:2 [
        "HTML" => 6
        "PDF" => 2
      ]
    ]
    "en" => array:11 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">Case and Research Letters</span>"
      "titulo" => "Urticarial Dermatitis&#46; A Cutaneous Reaction Pattern"
      "tienePdf" => "en"
      "tieneTextoCompleto" => "en"
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "929"
          "paginaFinal" => "932"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "es" => array:1 [
          "titulo" => "Dermatitis urticante&#46; Un patr&#243;n de reacci&#243;n cut&#225;nea"
        ]
      ]
      "contieneTextoCompleto" => array:1 [
        "en" => true
      ]
      "contienePdf" => array:1 [
        "en" => true
      ]
      "resumenGrafico" => array:2 [
        "original" => 0
        "multimedia" => array:7 [
          "identificador" => "fig0010"
          "etiqueta" => "Figure 2"
          "tipo" => "MULTIMEDIAFIGURA"
          "mostrarFloat" => true
          "mostrarDisplay" => false
          "figura" => array:1 [
            0 => array:4 [
              "imagen" => "gr2.jpeg"
              "Alto" => 1326
              "Ancho" => 1050
              "Tamanyo" => 138515
            ]
          ]
          "descripcion" => array:1 [
            "en" => "<p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">A&#44; Excoriated erythematous papules on the back of a patient&#46; B&#44; Use of the Fric test to confirm dermographism on the back of a patient with prurigo lesions at different stages of progression&#46;</p>"
          ]
        ]
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "M&#46;C&#46; Garc&#237;a del Pozo, I&#46; Poveda, P&#46; &#193;lvarez, J&#46;F&#46; Silvestre"
          "autores" => array:4 [
            0 => array:2 [
              "nombre" => "M&#46;C&#46;"
              "apellidos" => "Garc&#237;a del Pozo"
            ]
            1 => array:2 [
              "nombre" => "I&#46;"
              "apellidos" => "Poveda"
            ]
            2 => array:2 [
              "nombre" => "P&#46;"
              "apellidos" => "&#193;lvarez"
            ]
            3 => array:2 [
              "nombre" => "J&#46;F&#46;"
              "apellidos" => "Silvestre"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "en"
    "Traduccion" => array:1 [
      "es" => array:9 [
        "pii" => "S0001731018300310"
        "doi" => "10.1016/j.ad.2017.09.021"
        "estado" => "S300"
        "subdocumento" => ""
        "abierto" => array:3 [
          "ES" => true
          "ES2" => true
          "LATM" => true
        ]
        "gratuito" => true
        "lecturas" => array:1 [
          "total" => 0
        ]
        "idiomaDefecto" => "es"
        "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0001731018300310?idApp=UINPBA000044"
      ]
    ]
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219018303615?idApp=UINPBA000044"
    "url" => "/15782190/0000010900000010/v1_201812060634/S1578219018303615/v1_201812060634/en/main.assets"
  ]
  "en" => array:18 [
    "idiomaDefecto" => true
    "cabecera" => "<span class="elsevierStyleTextfn">Case and Research Letters</span>"
    "titulo" => "Three Cases of Scalp Sarcoidosis with Alopecia"
    "tieneTextoCompleto" => true
    "saludo" => "<span class="elsevierStyleItalic">To the Editor&#58;</span>"
    "paginas" => array:1 [
      0 => array:2 [
        "paginaInicial" => "933"
        "paginaFinal" => "934"
      ]
    ]
    "autores" => array:1 [
      0 => array:4 [
        "autoresLista" => "M&#46; Ishikawa, M&#46; Ohtsuka, T&#46; Yamamoto"
        "autores" => array:3 [
          0 => array:4 [
            "nombre" => "M&#46;"
            "apellidos" => "Ishikawa"
            "email" => array:1 [
              0 => "ishimasa&#64;fmu&#46;ac&#46;jp"
            ]
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">&#42;</span>"
                "identificador" => "cor0005"
              ]
            ]
          ]
          1 => array:2 [
            "nombre" => "M&#46;"
            "apellidos" => "Ohtsuka"
          ]
          2 => array:2 [
            "nombre" => "T&#46;"
            "apellidos" => "Yamamoto"
          ]
        ]
        "afiliaciones" => array:1 [
          0 => array:2 [
            "entidad" => "Departamento de Dermatolog&#237;a&#44; Universidad de Medicina de Fukushima&#44; Fukushima&#44; Jap&#243;n"
            "identificador" => "aff0005"
          ]
        ]
        "correspondencia" => array:1 [
          0 => array:3 [
            "identificador" => "cor0005"
            "etiqueta" => "&#8270;"
            "correspondencia" => "Corresponding author&#46;"
          ]
        ]
      ]
    ]
    "titulosAlternativos" => array:1 [
      "es" => array:1 [
        "titulo" => "Tres casos de sarcoidosis del cuero cabelludo con alopecia"
      ]
    ]
    "resumenGrafico" => array:2 [
      "original" => 0
      "multimedia" => array:7 [
        "identificador" => "fig0005"
        "etiqueta" => "Figure 1"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr1.jpeg"
            "Alto" => 879
            "Ancho" => 1750
            "Tamanyo" => 440271
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Clinical and histological characteristics of scalp sarcoidosis &#40;hematoxylin-eosin staining&#44; original magnification &#215;200&#41;&#46; A and B&#44; Case 1&#46; C and D&#44; Case 2&#46; E and F&#44; Case 3&#46;</p>"
        ]
      ]
    ]
    "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">Scalp sarcoidosis is a relatively infrequent disease that mainly affects African-American women&#46;<a class="elsevierStyleCrossRef" href="#bib0030"><span class="elsevierStyleSup">1</span></a> To date&#44; very few cases of this disease have been described&#46; We describe 3 patients with scalp sarcoidosis&#44; which manifested as infiltrated plaques with alopecia&#46;</p><p id="par0010" class="elsevierStylePara elsevierViewall">Case 1&#46; The patient was a 50-year-old woman who was admitted to our hospital with exertional dyspnea&#44; photophobia&#44; and skin rash&#46; The physical examination revealed several indurated brown plaques on both lower limbs&#44; as well as partial&#44; irregularly distributed alopecia and scaling erythema &#40;<a class="elsevierStyleCrossRef" href="#fig0005">Fig&#46; 1</a>A&#41;&#46; Radiography and computed tomography &#40;CT&#41; of the thorax revealed bilateral hilar lymphadenopathy &#40;BHL&#41; and mediastinal lymphadenopathy&#46; Serum levels of angiotensin converting enzyme &#40;ACE&#41; were elevated &#40;72&#46;8&#160;U&#47;L&#59; normal range&#44; 7&#8211;25&#160;U&#47;L&#41;&#46; The patient had a negative reaction in the tuberculin test&#46; The ophthalmological examination revealed uveitis&#46; Biopsy of the scalp showed non-necrotizing epithelioid granulomas located in the upper to mid dermis with minimal lymphocytic infiltration &#40;<a class="elsevierStyleCrossRef" href="#fig0005">Fig&#46; 1</a>B&#41;&#46; Naked granulomas were also detected in another sample taken from the leg&#46; The patient was treated with local topical steroids&#44; to which she responded poorly&#46;</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><p id="par0015" class="elsevierStylePara elsevierViewall">Case 2&#46; The patient was a 51-year-old man who was referred to our department with pulmonary sarcoidosis and uveitis&#46; He complained of blurred vision&#46; The ophthalmological examination revealed nodules in the iris&#44; inflammation of the anterior segment&#44; and vitreous opacity&#46; Radiography and a chest CT scan revealed BHL&#46; Serum ACE levels were elevated &#40;64&#46;5&#160;U&#47;L&#41;&#46; The patient had a negative reaction in the tuberculin test&#46; The physical examination revealed indurated reddish-brown plaques and regularly distributed areas of alopecia with black spots on the scalp &#40;<a class="elsevierStyleCrossRef" href="#fig0005">Fig&#46; 1</a>C&#41;&#44; as well as dark red subcutaneous nodules on the legs&#46; Biopsies of the scalp and legs revealed sarcoid granulomas located in the dermis &#40;<a class="elsevierStyleCrossRef" href="#fig0005">Fig&#46; 1</a>D&#41;&#46; The patient was treated with local topical steroids&#44; to which he responded poorly&#46;</p><p id="par0020" class="elsevierStylePara elsevierViewall">Case 3&#46; The patient was a 71-year-old man who was referred to our department with uveitis&#46; He reported skin rash on the scalp and the right leg&#46; Physical examination of the scalp revealed multiple erythematous&#44; scaly&#44; indurated areas and an egg-sized&#44; indurated alopecic plaque with black spots &#40;<a class="elsevierStyleCrossRef" href="#fig0005">Fig&#46; 1</a>E&#41;&#46; There were dark red subcutaneous nodules on the right leg&#46; Radiography and a chest CT scan revealed BHL&#46; Serum ACE levels were elevated &#40;42&#46;5&#160;U&#47;L&#41;&#46; The patient had a negative reaction in the tuberculin test&#46; He complained of myodesopsia and the ophthalmological examination revealed iritis and lens opacity&#46; Biopsy of the plaque on the scalp showed sarcoid granulomas extending from the mid to deep dermis &#40;<a class="elsevierStyleCrossRef" href="#fig0005">Fig&#46; 1</a>F&#41;&#46; The patient was treated with local topical steroids&#44; to which he responded poorly&#46;</p><p id="par0025" class="elsevierStylePara elsevierViewall">All 3 patients were treated with local topical steroids&#44; with a poor outcome in all cases&#46; No systemic treatments were administered&#46;</p><p id="par0030" class="elsevierStylePara elsevierViewall">The clinical presentation of scalp sarcoidosis consists of indurated verrucous plaques and nodular lesions&#44; often accompanied by alopecia&#44; and can resemble that of discoid lupus erythematosus&#44; necrobiosis lipoidica&#44; organoid nevus&#44; and cicatricial alopecia&#46;<a class="elsevierStyleCrossRefs" href="#bib0030"><span class="elsevierStyleSup">1&#8211;5</span></a> In general&#44; scalp sarcoidosis is accompanied by sarcoid skin lesions in other locations&#46;<a class="elsevierStyleCrossRefs" href="#bib0030"><span class="elsevierStyleSup">1&#44;2</span></a> Our 3 patients had infiltrated plaques with alopecia&#46; Unfortunately&#44; a trichoscopic examination&#44; which is necessary to identify the trichoscopic features of scalp sarcoidosis&#44; was not performed prior to biopsy&#46; The alopecia may have been a consequence of the effects of the sarcoid granuloma on the follicles or of follicular replacement by the granuloma&#46; All 3 patients had cutaneous sarcoidosis on the legs as well as the scalp&#46; Sarcoidosis of other organs is common in patients with scalp sarcoidosis&#44; and pulmonary and ophthalmologic sarcoidosis was observed in all 3 patients&#46; In most cases&#44; scalp sarcoidosis affects patients with active systemic sarcoidosis&#46; We have previous experience with 2 other cases of scalp sarcoidosis in which biopsies were taken from locations other than the scalp&#46; In both cases the patients&#8217; alopecia was strongly suggestive of sarcoidosis&#46; Scalp involvement is common in cases of cutaneous sarcoidosis&#44; and therefore a careful examination of the scalp should be performed if sarcoidosis is suspected&#46; Indeed&#44; scalp sarcoidosis may be less rare than previously thought&#46; It is therefore important to include a scalp examination in the clinical examination of sarcoidosis patients&#46;</p><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0005">Conflicts of Interest</span><p id="par0035" class="elsevierStylePara elsevierViewall">The authors declare that they have no conflicts of interest&#46;</p></span></span>"
    "textoCompletoSecciones" => array:1 [
      "secciones" => array:2 [
        0 => array:2 [
          "identificador" => "sec0005"
          "titulo" => "Conflicts of Interest"
        ]
        1 => array:1 [
          "titulo" => "References"
        ]
      ]
    ]
    "pdfFichero" => "main.pdf"
    "tienePdf" => true
    "fechaRecibido" => "2017-06-09"
    "fechaAceptado" => "2017-11-21"
    "NotaPie" => array:1 [
      0 => array:2 [
        "etiqueta" => "&#9734;"
        "nota" => "<p class="elsevierStyleNotepara" id="npar0005">Please cite this article as&#58; Ishikawa M&#44; Ohtsuka M&#44; Yamamoto T&#46; Three Cases of Scalp Sarcoidosis with Alopecia&#46; Actas Dermosifiliogr&#46; 2018&#59;109&#58;933&#8211;934&#46;</p>"
      ]
    ]
    "multimedia" => array:1 [
      0 => array:7 [
        "identificador" => "fig0005"
        "etiqueta" => "Figure 1"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr1.jpeg"
            "Alto" => 879
            "Ancho" => 1750
            "Tamanyo" => 440271
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Clinical and histological characteristics of scalp sarcoidosis &#40;hematoxylin-eosin staining&#44; original magnification &#215;200&#41;&#46; A and B&#44; Case 1&#46; C and D&#44; Case 2&#46; E and F&#44; Case 3&#46;</p>"
        ]
      ]
    ]
    "bibliografia" => array:2 [
      "titulo" => "References"
      "seccion" => array:1 [
        0 => array:2 [
          "identificador" => "bibs0015"
          "bibliografiaReferencia" => array:5 [
            0 => array:3 [
              "identificador" => "bib0030"
              "etiqueta" => "1"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Sarcoidosis of the scalp&#58; A case series and review of the literature"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "R&#46; Katta"
                            1 => "B&#46; Nelson"
                            2 => "D&#46; Chen"
                            3 => "H&#46; Roenigk"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "J Am Acad Dermatol"
                        "fecha" => "2000"
                        "volumen" => "42"
                        "paginaInicial" => "690"
                        "paginaFinal" => "692"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10727323"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            1 => array:3 [
              "identificador" => "bib0035"
              "etiqueta" => "2"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Scalp sarcoidosis with systemic involvement"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "M&#46; La Placa"
                            1 => "C&#46; Vincenzi"
                            2 => "C&#46; Misciali"
                            3 => "A&#46; Tosti"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "J Am Acad Dermatol"
                        "fecha" => "2008"
                        "volumen" => "59"
                        "paginaInicial" => "S126"
                        "paginaFinal" => "S127"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            2 => array:3 [
              "identificador" => "bib0040"
              "etiqueta" => "3"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Sarcoidal alopecia as a mimic of discoid lupus erythematosus"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "C&#46;L&#46; Henderson"
                            1 => "L&#46; Lafleur"
                            2 => "R&#46;D&#46; Sontheimer"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1016/j.jaad.2008.02.014"
                      "Revista" => array:6 [
                        "tituloSerie" => "J Am Acad Dermatol"
                        "fecha" => "2008"
                        "volumen" => "59"
                        "paginaInicial" => "143"
                        "paginaFinal" => "145"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/18378353"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            3 => array:3 [
              "identificador" => "bib0045"
              "etiqueta" => "4"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Sarcoidosis presenting as a scarring alopecia resembling necrobiosis lipoidica"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "K&#46;E&#46; Harman"
                            1 => "E&#46; Calonje"
                            2 => "A&#46; Robson"
                            3 => "M&#46;M&#46; Black"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Clin Exp Dermatol"
                        "fecha" => "2003"
                        "volumen" => "28"
                        "paginaInicial" => "565"
                        "paginaFinal" => "566"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12950362"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            4 => array:3 [
              "identificador" => "bib0050"
              "etiqueta" => "5"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Scalp sarcoidosis mimicking organoid nevus"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "T&#46; Yamamoto"
                            1 => "H&#46; Yokozeki"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1684/ejd.2014.2460"
                      "Revista" => array:6 [
                        "tituloSerie" => "Eur J Dermatol"
                        "fecha" => "2015"
                        "volumen" => "25"
                        "paginaInicial" => "78"
                        "paginaFinal" => "79"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/25513859"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
          ]
        ]
      ]
    ]
  ]
  "idiomaDefecto" => "en"
  "url" => "/15782190/0000010900000010/v1_201812060634/S1578219018303639/v1_201812060634/en/main.assets"
  "Apartado" => array:4 [
    "identificador" => "6157"
    "tipo" => "SECCION"
    "en" => array:2 [
      "titulo" => "Case and Research Letters"
      "idiomaDefecto" => true
    ]
    "idiomaDefecto" => "en"
  ]
  "PDF" => "https://static.elsevier.es/multimedia/15782190/0000010900000010/v1_201812060634/S1578219018303639/v1_201812060634/en/main.pdf?idApp=UINPBA000044&text.app=https://actasdermo.org/"
  "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219018303639?idApp=UINPBA000044"
]
Share
Journal Information

Statistics

Follow this link to access the full text of the article

Case and Research Letters
Three Cases of Scalp Sarcoidosis with Alopecia
Tres casos de sarcoidosis del cuero cabelludo con alopecia
M. Ishikawa
Corresponding author
ishimasa@fmu.ac.jp

Corresponding author.
, M. Ohtsuka, T. Yamamoto
Departamento de Dermatología, Universidad de Medicina de Fukushima, Fukushima, Japón
Read
12790
Times
was read the article
1872
Total PDF
10918
Total HTML
Share statistics
 array:24 [
  "pii" => "S1578219018303639"
  "issn" => "15782190"
  "doi" => "10.1016/j.adengl.2018.10.009"
  "estado" => "S300"
  "fechaPublicacion" => "2018-12-01"
  "aid" => "1930"
  "copyright" => "Elsevier Espa&#241;a&#44; S&#46;L&#46;U&#46; and AEDV"
  "copyrightAnyo" => "2018"
  "documento" => "simple-article"
  "crossmark" => 1
  "subdocumento" => "crp"
  "cita" => "Actas Dermosifiliogr. 2018;109:933-4"
  "abierto" => array:3 [
    "ES" => true
    "ES2" => true
    "LATM" => true
  ]
  "gratuito" => true
  "lecturas" => array:1 [
    "total" => 0
  ]
  "Traduccion" => array:1 [
    "es" => array:19 [
      "pii" => "S0001731018300929"
      "issn" => "00017310"
      "doi" => "10.1016/j.ad.2017.11.017"
      "estado" => "S300"
      "fechaPublicacion" => "2018-12-01"
      "aid" => "1930"
      "copyright" => "AEDV"
      "documento" => "simple-article"
      "crossmark" => 1
      "subdocumento" => "crp"
      "cita" => "Actas Dermosifiliogr. 2018;109:933-4"
      "abierto" => array:3 [
        "ES" => true
        "ES2" => true
        "LATM" => true
      ]
      "gratuito" => true
      "lecturas" => array:2 [
        "total" => 138
        "formatos" => array:2 [
          "HTML" => 105
          "PDF" => 33
        ]
      ]
      "es" => array:11 [
        "idiomaDefecto" => true
        "cabecera" => "<span class="elsevierStyleTextfn">Carta cient&#237;fico-cl&#237;nica</span>"
        "titulo" => "Tres casos de sarcoidosis del cuero cabelludo con alopecia"
        "tienePdf" => "es"
        "tieneTextoCompleto" => "es"
        "paginas" => array:1 [
          0 => array:2 [
            "paginaInicial" => "933"
            "paginaFinal" => "934"
          ]
        ]
        "titulosAlternativos" => array:1 [
          "en" => array:1 [
            "titulo" => "Three Cases of Scalp Sarcoidosis with Alopecia"
          ]
        ]
        "contieneTextoCompleto" => array:1 [
          "es" => true
        ]
        "contienePdf" => array:1 [
          "es" => true
        ]
        "resumenGrafico" => array:2 [
          "original" => 0
          "multimedia" => array:7 [
            "identificador" => "fig0005"
            "etiqueta" => "Figura 1"
            "tipo" => "MULTIMEDIAFIGURA"
            "mostrarFloat" => true
            "mostrarDisplay" => false
            "figura" => array:1 [
              0 => array:4 [
                "imagen" => "gr1.jpeg"
                "Alto" => 879
                "Ancho" => 1750
                "Tamanyo" => 439642
              ]
            ]
            "descripcion" => array:1 [
              "es" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Caracter&#237;sticas cl&#237;nicas e histol&#243;gicas de la sarcoidosis del cuero cabelludo &#40;a y b&#58; caso 1&#59; c y d&#58; caso 2&#59; e y f&#58; caso 3&#41;&#46; Tinci&#243;n hematoxilina-eosina&#44; ampliaci&#243;n del original &#215;200&#46;</p>"
            ]
          ]
        ]
        "autores" => array:1 [
          0 => array:2 [
            "autoresLista" => "M&#46; Ishikawa, M&#46; Ohtsuka, T&#46; Yamamoto"
            "autores" => array:3 [
              0 => array:2 [
                "nombre" => "M&#46;"
                "apellidos" => "Ishikawa"
              ]
              1 => array:2 [
                "nombre" => "M&#46;"
                "apellidos" => "Ohtsuka"
              ]
              2 => array:2 [
                "nombre" => "T&#46;"
                "apellidos" => "Yamamoto"
              ]
            ]
          ]
        ]
      ]
      "idiomaDefecto" => "es"
      "Traduccion" => array:1 [
        "en" => array:9 [
          "pii" => "S1578219018303639"
          "doi" => "10.1016/j.adengl.2018.10.009"
          "estado" => "S300"
          "subdocumento" => ""
          "abierto" => array:3 [
            "ES" => true
            "ES2" => true
            "LATM" => true
          ]
          "gratuito" => true
          "lecturas" => array:1 [
            "total" => 0
          ]
          "idiomaDefecto" => "en"
          "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219018303639?idApp=UINPBA000044"
        ]
      ]
      "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0001731018300929?idApp=UINPBA000044"
      "url" => "/00017310/0000010900000010/v1_201812060614/S0001731018300929/v1_201812060614/es/main.assets"
    ]
  ]
  "itemSiguiente" => array:19 [
    "pii" => "S1578219018303573"
    "issn" => "15782190"
    "doi" => "10.1016/j.adengl.2018.10.004"
    "estado" => "S300"
    "fechaPublicacion" => "2018-12-01"
    "aid" => "1974"
    "copyright" => "Elsevier Espa&#241;a&#44; S&#46;L&#46;U&#46; and AEDV"
    "documento" => "simple-article"
    "crossmark" => 1
    "subdocumento" => "crp"
    "cita" => "Actas Dermosifiliogr. 2018;109:934-6"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:1 [
      "total" => 0
    ]
    "en" => array:11 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">Case and Research Letters</span>"
      "titulo" => "Stewart-Bluefarb Syndrome&#58; Case Report and Review of the Literature"
      "tienePdf" => "en"
      "tieneTextoCompleto" => "en"
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "934"
          "paginaFinal" => "936"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "es" => array:1 [
          "titulo" => "S&#237;ndrome de Stewart-Bluefarb&#58; caso cl&#237;nico y revisi&#243;n de la literatura"
        ]
      ]
      "contieneTextoCompleto" => array:1 [
        "en" => true
      ]
      "contienePdf" => array:1 [
        "en" => true
      ]
      "resumenGrafico" => array:2 [
        "original" => 0
        "multimedia" => array:7 [
          "identificador" => "fig0005"
          "etiqueta" => "Figure 1"
          "tipo" => "MULTIMEDIAFIGURA"
          "mostrarFloat" => true
          "mostrarDisplay" => false
          "figura" => array:1 [
            0 => array:4 [
              "imagen" => "gr1.jpeg"
              "Alto" => 1134
              "Ancho" => 850
              "Tamanyo" => 160094
            ]
          ]
          "descripcion" => array:1 [
            "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Image showing raised lesions with perilesional eczema in the anterior pretibial surface and outermost supramalleolar region&#46; An ulcer with perilesional cutaneous hyperpigmentation is visible at the center of the image&#46;</p>"
          ]
        ]
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "V&#46;E&#46; Garc&#237;a Blanco, E&#46; Doiz Art&#225;zcoz, M&#46;C&#46; Galera Mart&#237;nez, M&#46; Rodr&#237;guez Pi&#241;ero"
          "autores" => array:4 [
            0 => array:2 [
              "nombre" => "V&#46;E&#46;"
              "apellidos" => "Garc&#237;a Blanco"
            ]
            1 => array:2 [
              "nombre" => "E&#46;"
              "apellidos" => "Doiz Art&#225;zcoz"
            ]
            2 => array:2 [
              "nombre" => "M&#46;C&#46;"
              "apellidos" => "Galera Mart&#237;nez"
            ]
            3 => array:2 [
              "nombre" => "M&#46;"
              "apellidos" => "Rodr&#237;guez Pi&#241;ero"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "en"
    "Traduccion" => array:1 [
      "es" => array:9 [
        "pii" => "S0001731018302126"
        "doi" => "10.1016/j.ad.2018.03.019"
        "estado" => "S300"
        "subdocumento" => ""
        "abierto" => array:3 [
          "ES" => true
          "ES2" => true
          "LATM" => true
        ]
        "gratuito" => true
        "lecturas" => array:1 [
          "total" => 0
        ]
        "idiomaDefecto" => "es"
        "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0001731018302126?idApp=UINPBA000044"
      ]
    ]
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219018303573?idApp=UINPBA000044"
    "url" => "/15782190/0000010900000010/v1_201812060634/S1578219018303573/v1_201812060634/en/main.assets"
  ]
  "itemAnterior" => array:19 [
    "pii" => "S1578219018303615"
    "issn" => "15782190"
    "doi" => "10.1016/j.adengl.2018.10.007"
    "estado" => "S300"
    "fechaPublicacion" => "2018-12-01"
    "aid" => "1889"
    "copyright" => "Elsevier Espa&#241;a&#44; S&#46;L&#46;U&#46; and AEDV"
    "documento" => "simple-article"
    "crossmark" => 1
    "subdocumento" => "crp"
    "cita" => "Actas Dermosifiliogr. 2018;109:929-32"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:2 [
      "total" => 8
      "formatos" => array:2 [
        "HTML" => 6
        "PDF" => 2
      ]
    ]
    "en" => array:11 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">Case and Research Letters</span>"
      "titulo" => "Urticarial Dermatitis&#46; A Cutaneous Reaction Pattern"
      "tienePdf" => "en"
      "tieneTextoCompleto" => "en"
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "929"
          "paginaFinal" => "932"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "es" => array:1 [
          "titulo" => "Dermatitis urticante&#46; Un patr&#243;n de reacci&#243;n cut&#225;nea"
        ]
      ]
      "contieneTextoCompleto" => array:1 [
        "en" => true
      ]
      "contienePdf" => array:1 [
        "en" => true
      ]
      "resumenGrafico" => array:2 [
        "original" => 0
        "multimedia" => array:7 [
          "identificador" => "fig0010"
          "etiqueta" => "Figure 2"
          "tipo" => "MULTIMEDIAFIGURA"
          "mostrarFloat" => true
          "mostrarDisplay" => false
          "figura" => array:1 [
            0 => array:4 [
              "imagen" => "gr2.jpeg"
              "Alto" => 1326
              "Ancho" => 1050
              "Tamanyo" => 138515
            ]
          ]
          "descripcion" => array:1 [
            "en" => "<p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">A&#44; Excoriated erythematous papules on the back of a patient&#46; B&#44; Use of the Fric test to confirm dermographism on the back of a patient with prurigo lesions at different stages of progression&#46;</p>"
          ]
        ]
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "M&#46;C&#46; Garc&#237;a del Pozo, I&#46; Poveda, P&#46; &#193;lvarez, J&#46;F&#46; Silvestre"
          "autores" => array:4 [
            0 => array:2 [
              "nombre" => "M&#46;C&#46;"
              "apellidos" => "Garc&#237;a del Pozo"
            ]
            1 => array:2 [
              "nombre" => "I&#46;"
              "apellidos" => "Poveda"
            ]
            2 => array:2 [
              "nombre" => "P&#46;"
              "apellidos" => "&#193;lvarez"
            ]
            3 => array:2 [
              "nombre" => "J&#46;F&#46;"
              "apellidos" => "Silvestre"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "en"
    "Traduccion" => array:1 [
      "es" => array:9 [
        "pii" => "S0001731018300310"
        "doi" => "10.1016/j.ad.2017.09.021"
        "estado" => "S300"
        "subdocumento" => ""
        "abierto" => array:3 [
          "ES" => true
          "ES2" => true
          "LATM" => true
        ]
        "gratuito" => true
        "lecturas" => array:1 [
          "total" => 0
        ]
        "idiomaDefecto" => "es"
        "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0001731018300310?idApp=UINPBA000044"
      ]
    ]
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219018303615?idApp=UINPBA000044"
    "url" => "/15782190/0000010900000010/v1_201812060634/S1578219018303615/v1_201812060634/en/main.assets"
  ]
  "en" => array:18 [
    "idiomaDefecto" => true
    "cabecera" => "<span class="elsevierStyleTextfn">Case and Research Letters</span>"
    "titulo" => "Three Cases of Scalp Sarcoidosis with Alopecia"
    "tieneTextoCompleto" => true
    "saludo" => "<span class="elsevierStyleItalic">To the Editor&#58;</span>"
    "paginas" => array:1 [
      0 => array:2 [
        "paginaInicial" => "933"
        "paginaFinal" => "934"
      ]
    ]
    "autores" => array:1 [
      0 => array:4 [
        "autoresLista" => "M&#46; Ishikawa, M&#46; Ohtsuka, T&#46; Yamamoto"
        "autores" => array:3 [
          0 => array:4 [
            "nombre" => "M&#46;"
            "apellidos" => "Ishikawa"
            "email" => array:1 [
              0 => "ishimasa&#64;fmu&#46;ac&#46;jp"
            ]
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">&#42;</span>"
                "identificador" => "cor0005"
              ]
            ]
          ]
          1 => array:2 [
            "nombre" => "M&#46;"
            "apellidos" => "Ohtsuka"
          ]
          2 => array:2 [
            "nombre" => "T&#46;"
            "apellidos" => "Yamamoto"
          ]
        ]
        "afiliaciones" => array:1 [
          0 => array:2 [
            "entidad" => "Departamento de Dermatolog&#237;a&#44; Universidad de Medicina de Fukushima&#44; Fukushima&#44; Jap&#243;n"
            "identificador" => "aff0005"
          ]
        ]
        "correspondencia" => array:1 [
          0 => array:3 [
            "identificador" => "cor0005"
            "etiqueta" => "&#8270;"
            "correspondencia" => "Corresponding author&#46;"
          ]
        ]
      ]
    ]
    "titulosAlternativos" => array:1 [
      "es" => array:1 [
        "titulo" => "Tres casos de sarcoidosis del cuero cabelludo con alopecia"
      ]
    ]
    "resumenGrafico" => array:2 [
      "original" => 0
      "multimedia" => array:7 [
        "identificador" => "fig0005"
        "etiqueta" => "Figure 1"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr1.jpeg"
            "Alto" => 879
            "Ancho" => 1750
            "Tamanyo" => 440271
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Clinical and histological characteristics of scalp sarcoidosis &#40;hematoxylin-eosin staining&#44; original magnification &#215;200&#41;&#46; A and B&#44; Case 1&#46; C and D&#44; Case 2&#46; E and F&#44; Case 3&#46;</p>"
        ]
      ]
    ]
    "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">Scalp sarcoidosis is a relatively infrequent disease that mainly affects African-American women&#46;<a class="elsevierStyleCrossRef" href="#bib0030"><span class="elsevierStyleSup">1</span></a> To date&#44; very few cases of this disease have been described&#46; We describe 3 patients with scalp sarcoidosis&#44; which manifested as infiltrated plaques with alopecia&#46;</p><p id="par0010" class="elsevierStylePara elsevierViewall">Case 1&#46; The patient was a 50-year-old woman who was admitted to our hospital with exertional dyspnea&#44; photophobia&#44; and skin rash&#46; The physical examination revealed several indurated brown plaques on both lower limbs&#44; as well as partial&#44; irregularly distributed alopecia and scaling erythema &#40;<a class="elsevierStyleCrossRef" href="#fig0005">Fig&#46; 1</a>A&#41;&#46; Radiography and computed tomography &#40;CT&#41; of the thorax revealed bilateral hilar lymphadenopathy &#40;BHL&#41; and mediastinal lymphadenopathy&#46; Serum levels of angiotensin converting enzyme &#40;ACE&#41; were elevated &#40;72&#46;8&#160;U&#47;L&#59; normal range&#44; 7&#8211;25&#160;U&#47;L&#41;&#46; The patient had a negative reaction in the tuberculin test&#46; The ophthalmological examination revealed uveitis&#46; Biopsy of the scalp showed non-necrotizing epithelioid granulomas located in the upper to mid dermis with minimal lymphocytic infiltration &#40;<a class="elsevierStyleCrossRef" href="#fig0005">Fig&#46; 1</a>B&#41;&#46; Naked granulomas were also detected in another sample taken from the leg&#46; The patient was treated with local topical steroids&#44; to which she responded poorly&#46;</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><p id="par0015" class="elsevierStylePara elsevierViewall">Case 2&#46; The patient was a 51-year-old man who was referred to our department with pulmonary sarcoidosis and uveitis&#46; He complained of blurred vision&#46; The ophthalmological examination revealed nodules in the iris&#44; inflammation of the anterior segment&#44; and vitreous opacity&#46; Radiography and a chest CT scan revealed BHL&#46; Serum ACE levels were elevated &#40;64&#46;5&#160;U&#47;L&#41;&#46; The patient had a negative reaction in the tuberculin test&#46; The physical examination revealed indurated reddish-brown plaques and regularly distributed areas of alopecia with black spots on the scalp &#40;<a class="elsevierStyleCrossRef" href="#fig0005">Fig&#46; 1</a>C&#41;&#44; as well as dark red subcutaneous nodules on the legs&#46; Biopsies of the scalp and legs revealed sarcoid granulomas located in the dermis &#40;<a class="elsevierStyleCrossRef" href="#fig0005">Fig&#46; 1</a>D&#41;&#46; The patient was treated with local topical steroids&#44; to which he responded poorly&#46;</p><p id="par0020" class="elsevierStylePara elsevierViewall">Case 3&#46; The patient was a 71-year-old man who was referred to our department with uveitis&#46; He reported skin rash on the scalp and the right leg&#46; Physical examination of the scalp revealed multiple erythematous&#44; scaly&#44; indurated areas and an egg-sized&#44; indurated alopecic plaque with black spots &#40;<a class="elsevierStyleCrossRef" href="#fig0005">Fig&#46; 1</a>E&#41;&#46; There were dark red subcutaneous nodules on the right leg&#46; Radiography and a chest CT scan revealed BHL&#46; Serum ACE levels were elevated &#40;42&#46;5&#160;U&#47;L&#41;&#46; The patient had a negative reaction in the tuberculin test&#46; He complained of myodesopsia and the ophthalmological examination revealed iritis and lens opacity&#46; Biopsy of the plaque on the scalp showed sarcoid granulomas extending from the mid to deep dermis &#40;<a class="elsevierStyleCrossRef" href="#fig0005">Fig&#46; 1</a>F&#41;&#46; The patient was treated with local topical steroids&#44; to which he responded poorly&#46;</p><p id="par0025" class="elsevierStylePara elsevierViewall">All 3 patients were treated with local topical steroids&#44; with a poor outcome in all cases&#46; No systemic treatments were administered&#46;</p><p id="par0030" class="elsevierStylePara elsevierViewall">The clinical presentation of scalp sarcoidosis consists of indurated verrucous plaques and nodular lesions&#44; often accompanied by alopecia&#44; and can resemble that of discoid lupus erythematosus&#44; necrobiosis lipoidica&#44; organoid nevus&#44; and cicatricial alopecia&#46;<a class="elsevierStyleCrossRefs" href="#bib0030"><span class="elsevierStyleSup">1&#8211;5</span></a> In general&#44; scalp sarcoidosis is accompanied by sarcoid skin lesions in other locations&#46;<a class="elsevierStyleCrossRefs" href="#bib0030"><span class="elsevierStyleSup">1&#44;2</span></a> Our 3 patients had infiltrated plaques with alopecia&#46; Unfortunately&#44; a trichoscopic examination&#44; which is necessary to identify the trichoscopic features of scalp sarcoidosis&#44; was not performed prior to biopsy&#46; The alopecia may have been a consequence of the effects of the sarcoid granuloma on the follicles or of follicular replacement by the granuloma&#46; All 3 patients had cutaneous sarcoidosis on the legs as well as the scalp&#46; Sarcoidosis of other organs is common in patients with scalp sarcoidosis&#44; and pulmonary and ophthalmologic sarcoidosis was observed in all 3 patients&#46; In most cases&#44; scalp sarcoidosis affects patients with active systemic sarcoidosis&#46; We have previous experience with 2 other cases of scalp sarcoidosis in which biopsies were taken from locations other than the scalp&#46; In both cases the patients&#8217; alopecia was strongly suggestive of sarcoidosis&#46; Scalp involvement is common in cases of cutaneous sarcoidosis&#44; and therefore a careful examination of the scalp should be performed if sarcoidosis is suspected&#46; Indeed&#44; scalp sarcoidosis may be less rare than previously thought&#46; It is therefore important to include a scalp examination in the clinical examination of sarcoidosis patients&#46;</p><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0005">Conflicts of Interest</span><p id="par0035" class="elsevierStylePara elsevierViewall">The authors declare that they have no conflicts of interest&#46;</p></span></span>"
    "textoCompletoSecciones" => array:1 [
      "secciones" => array:2 [
        0 => array:2 [
          "identificador" => "sec0005"
          "titulo" => "Conflicts of Interest"
        ]
        1 => array:1 [
          "titulo" => "References"
        ]
      ]
    ]
    "pdfFichero" => "main.pdf"
    "tienePdf" => true
    "fechaRecibido" => "2017-06-09"
    "fechaAceptado" => "2017-11-21"
    "NotaPie" => array:1 [
      0 => array:2 [
        "etiqueta" => "&#9734;"
        "nota" => "<p class="elsevierStyleNotepara" id="npar0005">Please cite this article as&#58; Ishikawa M&#44; Ohtsuka M&#44; Yamamoto T&#46; Three Cases of Scalp Sarcoidosis with Alopecia&#46; Actas Dermosifiliogr&#46; 2018&#59;109&#58;933&#8211;934&#46;</p>"
      ]
    ]
    "multimedia" => array:1 [
      0 => array:7 [
        "identificador" => "fig0005"
        "etiqueta" => "Figure 1"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr1.jpeg"
            "Alto" => 879
            "Ancho" => 1750
            "Tamanyo" => 440271
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Clinical and histological characteristics of scalp sarcoidosis &#40;hematoxylin-eosin staining&#44; original magnification &#215;200&#41;&#46; A and B&#44; Case 1&#46; C and D&#44; Case 2&#46; E and F&#44; Case 3&#46;</p>"
        ]
      ]
    ]
    "bibliografia" => array:2 [
      "titulo" => "References"
      "seccion" => array:1 [
        0 => array:2 [
          "identificador" => "bibs0015"
          "bibliografiaReferencia" => array:5 [
            0 => array:3 [
              "identificador" => "bib0030"
              "etiqueta" => "1"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Sarcoidosis of the scalp&#58; A case series and review of the literature"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "R&#46; Katta"
                            1 => "B&#46; Nelson"
                            2 => "D&#46; Chen"
                            3 => "H&#46; Roenigk"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "J Am Acad Dermatol"
                        "fecha" => "2000"
                        "volumen" => "42"
                        "paginaInicial" => "690"
                        "paginaFinal" => "692"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10727323"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            1 => array:3 [
              "identificador" => "bib0035"
              "etiqueta" => "2"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Scalp sarcoidosis with systemic involvement"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "M&#46; La Placa"
                            1 => "C&#46; Vincenzi"
                            2 => "C&#46; Misciali"
                            3 => "A&#46; Tosti"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "J Am Acad Dermatol"
                        "fecha" => "2008"
                        "volumen" => "59"
                        "paginaInicial" => "S126"
                        "paginaFinal" => "S127"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            2 => array:3 [
              "identificador" => "bib0040"
              "etiqueta" => "3"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Sarcoidal alopecia as a mimic of discoid lupus erythematosus"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "C&#46;L&#46; Henderson"
                            1 => "L&#46; Lafleur"
                            2 => "R&#46;D&#46; Sontheimer"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1016/j.jaad.2008.02.014"
                      "Revista" => array:6 [
                        "tituloSerie" => "J Am Acad Dermatol"
                        "fecha" => "2008"
                        "volumen" => "59"
                        "paginaInicial" => "143"
                        "paginaFinal" => "145"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/18378353"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            3 => array:3 [
              "identificador" => "bib0045"
              "etiqueta" => "4"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Sarcoidosis presenting as a scarring alopecia resembling necrobiosis lipoidica"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "K&#46;E&#46; Harman"
                            1 => "E&#46; Calonje"
                            2 => "A&#46; Robson"
                            3 => "M&#46;M&#46; Black"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Clin Exp Dermatol"
                        "fecha" => "2003"
                        "volumen" => "28"
                        "paginaInicial" => "565"
                        "paginaFinal" => "566"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12950362"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            4 => array:3 [
              "identificador" => "bib0050"
              "etiqueta" => "5"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Scalp sarcoidosis mimicking organoid nevus"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "T&#46; Yamamoto"
                            1 => "H&#46; Yokozeki"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1684/ejd.2014.2460"
                      "Revista" => array:6 [
                        "tituloSerie" => "Eur J Dermatol"
                        "fecha" => "2015"
                        "volumen" => "25"
                        "paginaInicial" => "78"
                        "paginaFinal" => "79"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/25513859"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
          ]
        ]
      ]
    ]
  ]
  "idiomaDefecto" => "en"
  "url" => "/15782190/0000010900000010/v1_201812060634/S1578219018303639/v1_201812060634/en/main.assets"
  "Apartado" => array:4 [
    "identificador" => "6157"
    "tipo" => "SECCION"
    "en" => array:2 [
      "titulo" => "Case and Research Letters"
      "idiomaDefecto" => true
    ]
    "idiomaDefecto" => "en"
  ]
  "PDF" => "https://static.elsevier.es/multimedia/15782190/0000010900000010/v1_201812060634/S1578219018303639/v1_201812060634/en/main.pdf?idApp=UINPBA000044&text.app=https://actasdermo.org/"
  "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219018303639?idApp=UINPBA000044"
]
Article information
ISSN: 15782190
Original language: English
The statistics are updated each day
Year/Month Html Pdf Total
2024 November 17 12 29
2024 October 201 41 242
2024 September 275 37 312
2024 August 341 60 401
2024 July 363 47 410
2024 June 382 50 432
2024 May 349 44 393
2024 April 309 38 347
2024 March 310 34 344
2024 February 305 42 347
2024 January 351 38 389
2023 December 326 18 344
2023 November 342 39 381
2023 October 361 26 387
2023 September 313 42 355
2023 August 271 19 290
2023 July 339 40 379
2023 June 307 32 339
2023 May 281 44 325
2023 April 238 27 265
2023 March 239 20 259
2023 February 209 17 226
2023 January 217 33 250
2022 December 97 29 126
2022 November 57 22 79
2022 October 45 18 63
2022 September 58 42 100
2022 August 55 72 127
2022 July 31 55 86
2022 June 26 20 46
2022 May 180 37 217
2022 April 303 29 332
2022 March 258 46 304
2022 February 275 23 298
2022 January 339 35 374
2021 December 170 42 212
2021 November 214 37 251
2021 October 190 45 235
2021 September 154 35 189
2021 August 197 36 233
2021 July 158 23 181
2021 June 129 29 158
2021 May 194 47 241
2021 April 387 87 474
2021 March 188 35 223
2021 February 141 28 169
2021 January 87 21 108
2020 December 67 18 85
2020 November 56 21 77
2020 October 37 16 53
2020 September 38 25 63
2020 August 21 18 39
2020 July 23 16 39
2020 June 27 22 49
2020 May 31 12 43
2020 April 22 21 43
2020 March 15 10 25
2020 February 2 0 2
Show all

Follow this link to access the full text of the article

Idiomas
Actas Dermo-Sifiliográficas
es en

¿Es usted profesional sanitario apto para prescribir o dispensar medicamentos?

Are you a health professional able to prescribe or dispense drugs?