was read the article
array:24 [ "pii" => "S1578219018300611" "issn" => "15782190" "doi" => "10.1016/j.adengl.2017.05.025" "estado" => "S300" "fechaPublicacion" => "2018-05-01" "aid" => "1795" "copyright" => "Elsevier España, S.L.U. and AEDV" "copyrightAnyo" => "2017" "documento" => "simple-article" "crossmark" => 1 "subdocumento" => "crp" "cita" => "Actas Dermosifiliogr. 2018;109:372-4" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 64 "formatos" => array:2 [ "EPUB" => 1 "HTML" => 63 ] ] "Traduccion" => array:1 [ "es" => array:19 [ "pii" => "S0001731017305094" "issn" => "00017310" "doi" => "10.1016/j.ad.2017.05.019" "estado" => "S300" "fechaPublicacion" => "2018-05-01" "aid" => "1795" "copyright" => "AEDV" "documento" => "simple-article" "crossmark" => 1 "subdocumento" => "crp" "cita" => "Actas Dermosifiliogr. 2018;109:372-4" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 127 "formatos" => array:2 [ "HTML" => 82 "PDF" => 45 ] ] "es" => array:11 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Carta Científico-Clínica</span>" "titulo" => "Metástasis cutánea de carcinoma de pulmón" "tienePdf" => "es" "tieneTextoCompleto" => "es" "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "372" "paginaFinal" => "374" ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Cutaneous Metastasis in a Patient With Lung Cancer" ] ] "contieneTextoCompleto" => array:1 [ "es" => true ] "contienePdf" => array:1 [ "es" => true ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:7 [ "identificador" => "fig0010" "etiqueta" => "Figura 2" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr2.jpeg" "Alto" => 2122 "Ancho" => 1500 "Tamanyo" => 399683 ] ] "descripcion" => array:1 [ "es" => "<p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">A) En la dermis y hasta el tejido celular subcutáneo, se aprecia una lesión solido-quística heterogénea de contorno polilobulado y en la que se aprecia una zona de dermis superficial respetada, superponible a la imagen anatomopatológica. B) En el Power Doppler presenta abundante vascularización periférica que penetra en la lesión desde varios polos.</p>" ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "C. Martínez-Morán, B. Echeverría-García, R. Khedaoui, J. Borbujo" "autores" => array:4 [ 0 => array:2 [ "nombre" => "C." "apellidos" => "Martínez-Morán" ] 1 => array:2 [ "nombre" => "B." "apellidos" => "Echeverría-García" ] 2 => array:2 [ "nombre" => "R." "apellidos" => "Khedaoui" ] 3 => array:2 [ "nombre" => "J." "apellidos" => "Borbujo" ] ] ] ] ] "idiomaDefecto" => "es" "Traduccion" => array:1 [ "en" => array:9 [ "pii" => "S1578219018300611" "doi" => "10.1016/j.adengl.2017.05.025" "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:1 [ "total" => 0 ] "idiomaDefecto" => "en" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219018300611?idApp=UINPBA000044" ] ] "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0001731017305094?idApp=UINPBA000044" "url" => "/00017310/0000010900000004/v1_201805050447/S0001731017305094/v1_201805050447/es/main.assets" ] ] "itemSiguiente" => array:19 [ "pii" => "S1578219018300507" "issn" => "15782190" "doi" => "10.1016/j.adengl.2018.03.008" "estado" => "S300" "fechaPublicacion" => "2018-05-01" "aid" => "1796" "copyright" => "Elsevier España, S.L.U. and AEDV" "documento" => "simple-article" "crossmark" => 1 "subdocumento" => "crp" "cita" => "Actas Dermosifiliogr. 2018;109:374-6" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 87 "formatos" => array:2 [ "HTML" => 84 "PDF" => 3 ] ] "en" => array:11 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Case and Research Letters</span>" "titulo" => "Bullous Necrotic Purpura Caused by <span class="elsevierStyleItalic">Scedosporium apiospermum</span> Presenting With a Sporotrichoid Pattern" "tienePdf" => "en" "tieneTextoCompleto" => "en" "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "374" "paginaFinal" => "376" ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Púrpura bullonecrótica de distribución esporotricoide por <span class="elsevierStyleItalic">Scedosporium apiospermum</span>" ] ] "contieneTextoCompleto" => array:1 [ "en" => true ] "contienePdf" => array:1 [ "en" => true ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:7 [ "identificador" => "fig0015" "etiqueta" => "Figure 3" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr3.jpeg" "Alto" => 600 "Ancho" => 900 "Tamanyo" => 71634 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">Fungal culture with white-grayish colonies that gradually take on a brownish color.</p>" ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "J. Company-Quiroga, C. Martínez-Morán, A. Moreno, J. Borbujo" "autores" => array:4 [ 0 => array:2 [ "nombre" => "J." "apellidos" => "Company-Quiroga" ] 1 => array:2 [ "nombre" => "C." "apellidos" => "Martínez-Morán" ] 2 => array:2 [ "nombre" => "A." "apellidos" => "Moreno" ] 3 => array:2 [ "nombre" => "J." "apellidos" => "Borbujo" ] ] ] ] ] "idiomaDefecto" => "en" "Traduccion" => array:1 [ "es" => array:9 [ "pii" => "S0001731017305100" "doi" => "10.1016/j.ad.2017.07.017" "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:1 [ "total" => 0 ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0001731017305100?idApp=UINPBA000044" ] ] "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219018300507?idApp=UINPBA000044" "url" => "/15782190/0000010900000004/v1_201805040442/S1578219018300507/v1_201805040442/en/main.assets" ] "itemAnterior" => array:18 [ "pii" => "S157821901830060X" "issn" => "15782190" "doi" => "10.1016/j.adengl.2017.04.012" "estado" => "S300" "fechaPublicacion" => "2018-05-01" "aid" => "1794" "documento" => "simple-article" "crossmark" => 1 "subdocumento" => "crp" "cita" => "Actas Dermosifiliogr. 2018;109:370-1" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 66 "formatos" => array:3 [ "EPUB" => 1 "HTML" => 64 "PDF" => 1 ] ] "en" => array:11 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Case and Research Letters</span>" "titulo" => "Rhinotillexomania" "tienePdf" => "en" "tieneTextoCompleto" => "en" "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "370" "paginaFinal" => "371" ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Rinotilexomanía" ] ] "contieneTextoCompleto" => array:1 [ "en" => true ] "contienePdf" => array:1 [ "en" => true ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:7 [ "identificador" => "fig0005" "etiqueta" => "Figure 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 648 "Ancho" => 900 "Tamanyo" => 96170 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Computed tomography scan showing perforation of the nasal septum but no other alterations.</p>" ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "C. Martín-Callizo, M. Sacristà, Y. Fortuño, R.M. Penín, M.J. Tribó" "autores" => array:5 [ 0 => array:2 [ "nombre" => "C." "apellidos" => "Martín-Callizo" ] 1 => array:2 [ "nombre" => "M." "apellidos" => "Sacristà" ] 2 => array:2 [ "nombre" => "Y." "apellidos" => "Fortuño" ] 3 => array:2 [ "nombre" => "R.M." "apellidos" => "Penín" ] 4 => array:2 [ "nombre" => "M.J." "apellidos" => "Tribó" ] ] ] ] ] "idiomaDefecto" => "en" "Traduccion" => array:1 [ "es" => array:9 [ "pii" => "S0001731017305082" "doi" => "10.1016/j.ad.2017.04.028" "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:1 [ "total" => 0 ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0001731017305082?idApp=UINPBA000044" ] ] "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S157821901830060X?idApp=UINPBA000044" "url" => "/15782190/0000010900000004/v1_201805040442/S157821901830060X/v1_201805040442/en/main.assets" ] "en" => array:16 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Case and Research Letters</span>" "titulo" => "Cutaneous Metastasis in a Patient With Lung Cancer" "tieneTextoCompleto" => true "saludo" => "<span class="elsevierStyleItalic">To the Editor:</span>" "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "372" "paginaFinal" => "374" ] ] "autores" => array:1 [ 0 => array:4 [ "autoresLista" => "C. Martínez-Morán, B. Echeverría-García, R. Khedaoui, J. Borbujo" "autores" => array:4 [ 0 => array:4 [ "nombre" => "C." "apellidos" => "Martínez-Morán" "email" => array:1 [ 0 => "cmmoran@salud.madrid.org" ] "referencia" => array:2 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] 1 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">*</span>" "identificador" => "cor0005" ] ] ] 1 => array:3 [ "nombre" => "B." "apellidos" => "Echeverría-García" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] ] ] 2 => array:3 [ "nombre" => "R." "apellidos" => "Khedaoui" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff0010" ] ] ] 3 => array:3 [ "nombre" => "J." "apellidos" => "Borbujo" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] ] ] ] "afiliaciones" => array:2 [ 0 => array:3 [ "entidad" => "Servicio de Dermatología, Hospital Universitario de Fuenlabrada, Madrid, Spain" "etiqueta" => "a" "identificador" => "aff0005" ] 1 => array:3 [ "entidad" => "Servicio de Anatomía Patológica, Hospital Universitario de Fuenlabrada, Madrid, Spain" "etiqueta" => "b" "identificador" => "aff0010" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "⁎" "correspondencia" => "Corresponding author." ] ] ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Metástasis cutánea de carcinoma de pulmón" ] ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:7 [ "identificador" => "fig0015" "etiqueta" => "Figure 3" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr3.jpeg" "Alto" => 611 "Ancho" => 1500 "Tamanyo" => 298292 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">Infiltration of the dermis by a proliferation of cells forming solid nests of cells (A) (hematoxylin-eosin, original magnification ×4) with a squamous growth pattern and marked nuclear pleomorphism, prominent nucleoli, and several mitotic figures (B) (hematoxylin-eosin, original magnification ×400).</p>" ] ] ] "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">A 55-year-old woman who had smoked since the age of 20 years and had no known diseases or drug allergies was under follow-up at the general surgery department for a painful lesion of 2 months’ duration on the right buttock that had grown despite 2 cycles of oral antibiotics prescribed by her primary care physician. The clinical diagnosis was an infected epidermal cyst and the lesion was drained in the general surgery department. Despite follow-up care over a month, the wound did not heal and the patient was referred to us for evaluation. Physical examination showed an erythematous-violaceous indurated plaque with a 5-cm diameter on the upper outer quadrant of the right buttock (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>). The plaque, which was hard on palpation, contained an ulcer measuring 15<span class="elsevierStyleHsp" style=""></span>mm at its widest diameter secondary to the surgical drainage. The central area of the ulcer was very deep and its walls contained a solid yellowish-white material. When questioned, the patient reported that she had lost 15<span class="elsevierStyleHsp" style=""></span>kg in 2 months, a loss that she attributed to a naturopathic diet. We examined the lesion by ultrasound and performed a wedge biopsy for histologic and microbiologic studies. The fungal, bacterial, and mycobacterial cultures were all negative. Color Doppler imaging on a MyLabClass <span class="elsevierStyleSmallCaps">C</span> machine (Esaote) equipped with an 18-MHz probe revealed a heterogeneous solid-cystic lesion measuring 45<span class="elsevierStyleHsp" style=""></span>×<span class="elsevierStyleHsp" style=""></span>27<span class="elsevierStyleHsp" style=""></span>mm in the dermis and extending into the subcutaneous tissue. The lesion also had anechoic central areas admixed with hyperechoic areas with well-defined borders (<a class="elsevierStyleCrossRef" href="#fig0010">Fig. 2</a>). It displayed posterior reinforcement and Power Doppler imaging showed peripheral vascular poles. The above findings (the heterogeneity and significant vascularity at several poles of the lesion) suggested malignancy, which allowed us to request a rush histology study. Histologic examination showed infiltration of the dermis by a malignant epithelial proliferation of cells with a squamous pattern of growth, marked nuclear pleomorphism, prominent nucleoli, and several mitotic figures; the proliferation formed solid nests with evident intercellular bridges and apoptotic cells (<a class="elsevierStyleCrossRef" href="#fig0015">Fig. 3</a> A and B). There was also extensive necrosis and no signs of connection with the epidermis. The proliferation extended as far as the peripheral and deep borders of the biopsy specimen. With a diagnosis of poorly differentiated squamous cell carcinoma, we requested a chest radiograph, which showed a nodule in the left lung and a focal interstitial infiltrate containing septal lines and images of nodules in the right lung. Positron emission-tomography-computed tomography confirmed the presence of a disseminated stage <span class="elsevierStyleSmallCaps">IV</span> lung tumor with a large pulmonary mass in the right upper lobe and multiple lung and bone metastases. The study also showed a hypermetabolic soft tissue mass corresponding to the skin lesion on the right buttock. The patient opted to have the lesion completely excised. She was enrolled in a palliative care clinical trial by the oncology department, but died 7 months later.</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><elsevierMultimedia ident="fig0010"></elsevierMultimedia><elsevierMultimedia ident="fig0015"></elsevierMultimedia><p id="par0010" class="elsevierStylePara elsevierViewall">The skin is a rare site of metastasis from internal malignancies and is estimated to be involved in 0.5% to 9% of all cases.<a class="elsevierStyleCrossRefs" href="#bib0055"><span class="elsevierStyleSup">1–4</span></a> All types of malignant tumors can produce cutaneous metastasis, but the type most likely to do this varies considerably from one series to the next.<a class="elsevierStyleCrossRefs" href="#bib0065"><span class="elsevierStyleSup">3–6</span></a></p><p id="par0015" class="elsevierStylePara elsevierViewall">Cutaneous metastases from lung tumors are rare (0%-4% depending on the series) and are associated with a very poor prognosis as the mean survival is just 3 to 5 months.<a class="elsevierStyleCrossRef" href="#bib0085"><span class="elsevierStyleSup">7</span></a> Few cases have been reported in the literature.<a class="elsevierStyleCrossRefs" href="#bib0080"><span class="elsevierStyleSup">6–8</span></a> The clinical presentation of cutaneous metastases is highly variable and includes macules, papules, nodules, and ulcerated lesions. Cutaneous metastases from the lung are typically located on the chest wall, the neck, the abdominal wall, the scalp, or the face.<a class="elsevierStyleCrossRef" href="#bib0080"><span class="elsevierStyleSup">6</span></a> Squamous cell carcinoma is the least common histologic subtype of cutaneous metastasis from the lung. Metastasis to the skin is the presenting manifestation of lung cancer in less than 1% of cases, and a high index of clinical suspicion is therefore essential. Many cases are detected late in the course of disease and have no bearing on prognosis. However, in some cases such as ours, their detection permits the diagnosis and treatment of an unknown primary tumor.</p><p id="par0020" class="elsevierStylePara elsevierViewall">High-frequency ultrasound is a fast, affordable, noninvasive technique that can strongly predict malignancy in cases of cutaneous metastasis. Very few articles have been published on ultrasound studies of cutaneous metastases from tumors other than melanoma.<a class="elsevierStyleCrossRefs" href="#bib0065"><span class="elsevierStyleSup">3,9,10</span></a> Giovagnorio et al.<a class="elsevierStyleCrossRef" href="#bib0065"><span class="elsevierStyleSup">3</span></a> found that a polycyclic shape and hypervascularity with multiple peripheral poles were indicative of cutaneous metastasis. The differential diagnosis should include inflamed epidermal cysts, cutaneous lymphomas (which can be accompanied by considerable inflammation), and cystic areas in patients with hidradenitis suppurativa. In this last case, sinus tracts and drainage sinuses will be observed both clinically and by ultrasound.</p><p id="par0025" class="elsevierStylePara elsevierViewall">We have presented the case of a young woman with a cutaneous metastasis on the buttock that was the presenting manifestation of a squamous cell lung cancer in which ultrasound examination of the lesion suggested malignancy, allowing us to accelerate the diagnostic process.</p><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0005">Conflicts of Interest</span><p id="par0030" class="elsevierStylePara elsevierViewall">The authors declare that they have no conflicts of interest.</p></span></span>" "textoCompletoSecciones" => array:1 [ "secciones" => array:2 [ 0 => array:2 [ "identificador" => "sec0005" "titulo" => "Conflicts of Interest" ] 1 => array:1 [ "titulo" => "References" ] ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "NotaPie" => array:1 [ 0 => array:2 [ "etiqueta" => "☆" "nota" => "<p class="elsevierStyleNotepara" id="npar0005">Please cite this article as: Martínez-Morán C, Echeverría-García B, Khedaoui R, Borbujo J. Metástasis cutánea de carcinoma de pulmón. Actas Dermosifiliogr. 2018;109:372–374.</p>" ] ] "multimedia" => array:3 [ 0 => array:7 [ "identificador" => "fig0005" "etiqueta" => "Figure 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 600 "Ancho" => 900 "Tamanyo" => 83662 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Well-delimited, very hard erythematous-violaceous nodular lesion in the upper outer quadrant of the right buttock with a very deep central ulcer containing a yellowish-white material.</p>" ] ] 1 => array:7 [ "identificador" => "fig0010" "etiqueta" => "Figure 2" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr2.jpeg" "Alto" => 2122 "Ancho" => 1500 "Tamanyo" => 399688 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">A, Heterogeneous polylobulated solid-cystic lesion in the dermis and extending into the subcutaneous tissue, coinciding with the histologic image; note the sparing of the superficial area of the dermis. B, Power Doppler imaging showing abundant peripheral vascularity penetrating the lesion from several poles.</p>" ] ] 2 => array:7 [ "identificador" => "fig0015" "etiqueta" => "Figure 3" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr3.jpeg" "Alto" => 611 "Ancho" => 1500 "Tamanyo" => 298292 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">Infiltration of the dermis by a proliferation of cells forming solid nests of cells (A) (hematoxylin-eosin, original magnification ×4) with a squamous growth pattern and marked nuclear pleomorphism, prominent nucleoli, and several mitotic figures (B) (hematoxylin-eosin, original magnification ×400).</p>" ] ] ] "bibliografia" => array:2 [ "titulo" => "References" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0015" "bibliografiaReferencia" => array:10 [ 0 => array:3 [ "identificador" => "bib0055" "etiqueta" => "1" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Clinical features of skin metastasis from lung cancer" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "T. Hidaka" 1 => "Y. Ishii" 2 => "S. Kitamura" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Intern Med" "fecha" => "1996" "volumen" => "35" "paginaInicial" => "459" "paginaFinal" => "462" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8835596" "web" => "Medline" ] ] ] ] ] ] ] ] 1 => array:3 [ "identificador" => "bib0060" "etiqueta" => "2" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Lung cancer with skin metastasis" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "T. Terashima" 1 => "M. Kanazawa" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Chest" "fecha" => "1994" "volumen" => "106" "paginaInicial" => "1448" "paginaFinal" => "1450" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/7956399" "web" => "Medline" ] ] ] ] ] ] ] ] 2 => array:3 [ "identificador" => "bib0065" "etiqueta" => "3" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "High-resolution and color doppler sonography in the evaluation of skin metastases" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "F. Giovagnorio" 1 => "C. Valentini" 2 => "A. Paonessa" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "J Ultrasound Med." "fecha" => "2003" "volumen" => "22" "paginaInicial" => "1017" "paginaFinal" => "1022" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/14606556" "web" => "Medline" ] ] ] ] ] ] ] ] 3 => array:3 [ "identificador" => "bib0070" "etiqueta" => "4" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Rates of cutaneous metastases from different internal malignancies: Experience from a Taiwanese medical center" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "S.C. Hu" 1 => "G.S. Chen" 2 => "C.S. Wu" 3 => "C.Y. Chai" 4 => "W.T. Chen" 5 => "C.C. Lan" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/j.jaad.2008.10.007" "Revista" => array:6 [ "tituloSerie" => "J Am Acad Dermatol." "fecha" => "2009" "volumen" => "60" "paginaInicial" => "379" "paginaFinal" => "387" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/19056145" "web" => "Medline" ] ] ] ] ] ] ] ] 4 => array:3 [ "identificador" => "bib0075" "etiqueta" => "5" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Cutaneous metastases of internal tumors" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "M.C. Fernández-Antón Martínez" 1 => "V. Parra-Blanco" 2 => "J.A. Avilés Izquierdo" 3 => "R.M. Suárez Fernández" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/j.ad.2012.06.005" "Revista" => array:6 [ "tituloSerie" => "Actas Dermosifiliogr." "fecha" => "2013" "volumen" => "104" "paginaInicial" => "841" "paginaFinal" => "853" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/22853962" "web" => "Medline" ] ] ] ] ] ] ] ] 5 => array:3 [ "identificador" => "bib0080" "etiqueta" => "6" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Skin metastases from primary lung cancer. Report of three cases and a brief review" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "A. Ardavanis" 1 => "G. Orphnaos" 2 => "G. Ionnidid" 3 => "G. Rigatos" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "In Vivo." "fecha" => "2006" "volumen" => "20" "paginaInicial" => "671" "paginaFinal" => "673" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/17091776" "web" => "Medline" ] ] ] ] ] ] ] ] 6 => array:3 [ "identificador" => "bib0085" "etiqueta" => "7" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Cutaneous metastasis from lung cancer: Retrospective analysis of 30 patients" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "J. Marcoval" 1 => "R.M. Penín" 2 => "R. Llatjós" 3 => "I. Martínez-Ballarín" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1111/j.1440-0960.2011.00828.x" "Revista" => array:6 [ "tituloSerie" => "Australas J Dermatol." "fecha" => "2012" "volumen" => "53" "paginaInicial" => "288" "paginaFinal" => "290" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/23157780" "web" => "Medline" ] ] ] ] ] ] ] ] 7 => array:3 [ "identificador" => "bib0090" "etiqueta" => "8" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Cutaneous metastasis of lung carcinoma: A retrospective study of 12 cases" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "S. Dhambri" 1 => "I. Zendah" 2 => "A. Ayadi-Kaddour" 3 => "O. Adouni" 4 => "F. Eel Mezni" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1111/j.1468-3083.2010.03818.x" "Revista" => array:6 [ "tituloSerie" => "J Eur Acad Dermatol Venereol." "fecha" => "2011" "volumen" => "25" "paginaInicial" => "722" "paginaFinal" => "726" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/20735519" "web" => "Medline" ] ] ] ] ] ] ] ] 8 => array:3 [ "identificador" => "bib0095" "etiqueta" => "9" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Cutaneous metastasis of esophageal adenocarcinoma with an unusual presentation" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "S. Riley" 1 => "T. Wah" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1002/jcu.20295" "Revista" => array:6 [ "tituloSerie" => "J Clin Ultrasound." "fecha" => "2007" "volumen" => "35" "paginaInicial" => "289" "paginaFinal" => "292" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/17366561" "web" => "Medline" ] ] ] ] ] ] ] ] 9 => array:3 [ "identificador" => "bib0100" "etiqueta" => "10" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Ultrasonography as a diagnostic tool for skin metastasis of a prostate adenocarcinoma" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "H. Corominas" 1 => "P. Estrada" 2 => "D. Reina" 3 => "D. Cerdà-Gabaroi" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/j.reuma.2015.03.002" "Revista" => array:6 [ "tituloSerie" => "Reumatol Clin." "fecha" => "2016" "volumen" => "12" "paginaInicial" => "54" "paginaFinal" => "56" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/25921357" "web" => "Medline" ] ] ] ] ] ] ] ] ] ] ] ] ] "idiomaDefecto" => "en" "url" => "/15782190/0000010900000004/v1_201805040442/S1578219018300611/v1_201805040442/en/main.assets" "Apartado" => array:4 [ "identificador" => "6157" "tipo" => "SECCION" "en" => array:2 [ "titulo" => "Case and Research Letters" "idiomaDefecto" => true ] "idiomaDefecto" => "en" ] "PDF" => "https://static.elsevier.es/multimedia/15782190/0000010900000004/v1_201805040442/S1578219018300611/v1_201805040442/en/main.pdf?idApp=UINPBA000044&text.app=https://actasdermo.org/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219018300611?idApp=UINPBA000044" ]
Year/Month | Html | Total | |
---|---|---|---|
2024 November | 9 | 2 | 11 |
2024 October | 104 | 49 | 153 |
2024 September | 125 | 23 | 148 |
2024 August | 173 | 52 | 225 |
2024 July | 134 | 31 | 165 |
2024 June | 126 | 32 | 158 |
2024 May | 104 | 45 | 149 |
2024 April | 101 | 28 | 129 |
2024 March | 115 | 21 | 136 |
2024 February | 107 | 32 | 139 |
2024 January | 86 | 32 | 118 |
2023 December | 103 | 24 | 127 |
2023 November | 97 | 40 | 137 |
2023 October | 94 | 30 | 124 |
2023 September | 101 | 35 | 136 |
2023 August | 103 | 31 | 134 |
2023 July | 120 | 38 | 158 |
2023 June | 140 | 27 | 167 |
2023 May | 105 | 28 | 133 |
2023 April | 119 | 32 | 151 |
2023 March | 110 | 33 | 143 |
2023 February | 122 | 32 | 154 |
2023 January | 80 | 29 | 109 |
2022 December | 59 | 45 | 104 |
2022 November | 40 | 33 | 73 |
2022 October | 38 | 30 | 68 |
2022 September | 22 | 49 | 71 |
2022 August | 20 | 37 | 57 |
2022 July | 21 | 35 | 56 |
2022 June | 21 | 28 | 49 |
2022 May | 126 | 39 | 165 |
2022 April | 162 | 53 | 215 |
2022 March | 122 | 57 | 179 |
2022 February | 85 | 49 | 134 |
2022 January | 103 | 59 | 162 |
2021 December | 74 | 40 | 114 |
2021 November | 97 | 62 | 159 |
2021 October | 84 | 57 | 141 |
2021 September | 61 | 34 | 95 |
2021 August | 43 | 48 | 91 |
2021 July | 35 | 35 | 70 |
2021 June | 49 | 35 | 84 |
2021 May | 38 | 60 | 98 |
2021 April | 64 | 97 | 161 |
2021 March | 55 | 31 | 86 |
2021 February | 57 | 30 | 87 |
2021 January | 39 | 21 | 60 |
2020 December | 19 | 21 | 40 |
2020 November | 28 | 27 | 55 |
2020 October | 35 | 14 | 49 |
2020 September | 27 | 20 | 47 |
2020 August | 26 | 24 | 50 |
2020 July | 26 | 23 | 49 |
2020 June | 34 | 27 | 61 |
2020 May | 22 | 20 | 42 |
2020 April | 27 | 17 | 44 |
2020 March | 34 | 19 | 53 |
2020 February | 1 | 0 | 1 |
2020 January | 4 | 0 | 4 |
2019 December | 8 | 0 | 8 |
2019 November | 4 | 0 | 4 |
2019 September | 8 | 0 | 8 |
2019 August | 4 | 0 | 4 |
2019 July | 4 | 0 | 4 |
2019 June | 4 | 0 | 4 |
2019 May | 8 | 0 | 8 |
2019 April | 2 | 0 | 2 |
2019 March | 2 | 0 | 2 |
2019 February | 4 | 0 | 4 |
2018 December | 4 | 0 | 4 |
2018 November | 2 | 0 | 2 |
2018 October | 2 | 0 | 2 |
2018 September | 2 | 0 | 2 |
2018 May | 1 | 0 | 1 |