Images in Dermatology
Male breast cancer mimicking melanoma
Cancer de mama en un varón simulando un melanoma
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Hematoxylin and eosin (H&E), original magnification<span class="elsevierStyleHsp" style=""></span>×<span class="elsevierStyleHsp" style=""></span>2. B, Periglandular lymphoplasmacytic infiltrates. H&E, original magnification<span class="elsevierStyleHsp" style=""></span>×<span class="elsevierStyleHsp" style=""></span>40. C, Positivity for CD20 in the lymphoplasmacytic infiltrate. CD20 immunohistochemical stain, original magnification<span class="elsevierStyleHsp" style=""></span>×<span class="elsevierStyleHsp" style=""></span>10. D, Negativity for CD38 in the neoplastic infiltrate. The few plasma cells that are present are not monoclonal cells and are positive for CD38. CD38 immunohistochemical stain, original magnification<span class="elsevierStyleHsp" style=""></span>×<span class="elsevierStyleHsp" style=""></span>10.</p>" ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "S. Oscoz-Jaime, A.D. Agulló-Pérez, C. Llanos-Chavarri, J.I. 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Kueder Pajares, A.J. García Malinis, P. Manchado López" "autores" => array:3 [ 0 => array:4 [ "nombre" => "T." "apellidos" => "Kueder Pajares" "email" => array:1 [ 0 => "Tkueder@hotmail.com" ] "referencia" => array:2 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] 1 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">*</span>" "identificador" => "cor0005" ] ] ] 1 => array:3 [ "nombre" => "A.J." "apellidos" => "García Malinis" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff0010" ] ] ] 2 => array:3 [ "nombre" => "P." "apellidos" => "Manchado López" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] ] ] ] "afiliaciones" => array:2 [ 0 => array:3 [ "entidad" => "Servicio de Dermatología y Venereología, Hospital Clínico Universitario de Valladolid, Valladolid, Spain" "etiqueta" => "a" "identificador" => "aff0005" ] 1 => array:3 [ "entidad" => "Servicio de Dermatología y Venereología, Hospital de Huesca, Huesca, Spain" "etiqueta" => "b" "identificador" => "aff0010" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "⁎" "correspondencia" => "Corresponding author." ] ] ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Cancer de mama en un varón simulando un melanoma" ] ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:6 [ "identificador" => "fig0010" "etiqueta" => "Figure 2" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr2.jpeg" "Alto" => 995 "Ancho" => 1333 "Tamanyo" => 191248 ] ] ] ] "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">A 72-year-old man presented with a one year progressive growing lesion located on the right nipple. He was asymptomatic. A round plaque occupying all nipple and areola was observed. The plaque presented with ragged edges protruding from the areola, had heterogeneous pigmentation, was indurated and adhered to deep planes. Dermoscopy showed telangiectasia, pseudopods and areas suggestive of regression (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>). The differential diagnosis included melanoma, breast cancer and pigmented basal cell carcinoma. An incisional biopsy was performed. Histology confirmed the diagnosis of ductal breast carcinoma (<a class="elsevierStyleCrossRef" href="#fig0010">Fig. 2</a>).</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><elsevierMultimedia ident="fig0010"></elsevierMultimedia><p id="par0010" class="elsevierStylePara elsevierViewall">Breast carcinoma is an infrequent condition among males. The average age of diagnosis is 60–65 years. In up to 25% cutaneous involvement is the first manifestation. Despite similar prognosis between sexes at the same stage, a lower survival rate in males is accounted by late diagnosis. This image shows an atypical cutaneous presentation of breast carcinoma mimicking melanoma.</p></span>" "pdfFichero" => "main.pdf" "tienePdf" => true "multimedia" => array:2 [ 0 => array:6 [ "identificador" => "fig0005" "etiqueta" => "Figure 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 1600 "Ancho" => 2133 "Tamanyo" => 333867 ] ] ] 1 => array:6 [ "identificador" => "fig0010" "etiqueta" => "Figure 2" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr2.jpeg" "Alto" => 995 "Ancho" => 1333 "Tamanyo" => 191248 ] ] ] ] ] "idiomaDefecto" => "en" "url" => "/15782190/0000010900000001/v1_201801020547/S1578219017304018/v1_201801020547/en/main.assets" "Apartado" => array:4 [ "identificador" => "41141" "tipo" => "SECCION" "en" => array:2 [ "titulo" => "Images in Dermatology" "idiomaDefecto" => true ] "idiomaDefecto" => "en" ] "PDF" => "https://static.elsevier.es/multimedia/15782190/0000010900000001/v1_201801020547/S1578219017304018/v1_201801020547/en/main.pdf?idApp=UINPBA000044&text.app=https://actasdermo.org/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219017304018?idApp=UINPBA000044" ]
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