Case and Research Letters
A Tumor in Images: Anetodermic Pilomatrixoma
Un tumor en imágenes: pilomatrixoma anetodérmico
Read
7531
Timeswas read the article
2286
Total PDF
5245
Total HTML
Share statistics
array:25 [ "pii" => "S1578219015000281" "issn" => "15782190" "doi" => "10.1016/j.adengl.2015.01.015" "estado" => "S300" "fechaPublicacion" => "2015-04-01" "aid" => "1048" "copyright" => "Elsevier España, S.L.U. and AEDV" "copyrightAnyo" => "2014" "documento" => "simple-article" "crossmark" => 1 "licencia" => "http://creativecommons.org/licenses/by-nc-nd/4.0/" "subdocumento" => "cor" "cita" => "Actas Dermosifiliogr. 2015;106:241-3" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 1150 "formatos" => array:3 [ "EPUB" => 55 "HTML" => 570 "PDF" => 525 ] ] "Traduccion" => array:1 [ "es" => array:19 [ "pii" => "S0001731014004074" "issn" => "00017310" "doi" => "10.1016/j.ad.2014.07.003" "estado" => "S300" "fechaPublicacion" => "2015-04-01" "aid" => "1048" "copyright" => "Elsevier España, S.L.U. y AEDV" "documento" => "simple-article" "crossmark" => 1 "subdocumento" => "cor" "cita" => "Actas Dermosifiliogr. 2015;106:241-3" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 1581 "formatos" => array:3 [ "EPUB" => 3 "HTML" => 904 "PDF" => 674 ] ] "es" => array:11 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Carta científico-clínicas</span>" "titulo" => "Un tumor en imágenes: pilomatrixoma anetodérmico" "tienePdf" => "es" "tieneTextoCompleto" => "es" "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "241" "paginaFinal" => "243" ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "A Tumor in Images: Anetodermic Pilomatrixoma" ] ] "contieneTextoCompleto" => array:1 [ "es" => true ] "contienePdf" => array:1 [ "es" => true ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:7 [ "identificador" => "fig0005" "etiqueta" => "Figura 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 667 "Ancho" => 1000 "Tamanyo" => 135926 ] ] "descripcion" => array:1 [ "es" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Imagen clínica: tumoración excrecente de 15<span class="elsevierStyleHsp" style=""></span>mm de diámetro, bien delimitada en la región frontoparietal derecha con varios colores.</p>" ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "C. Martínez-Morán, B. Echeverría-García, L. Nájera, J. Borbujo" "autores" => array:4 [ 0 => array:2 [ "nombre" => "C." "apellidos" => "Martínez-Morán" ] 1 => array:2 [ "nombre" => "B." "apellidos" => "Echeverría-García" ] 2 => array:2 [ "nombre" => "L." "apellidos" => "Nájera" ] 3 => array:2 [ "nombre" => "J." "apellidos" => "Borbujo" ] ] ] ] ] "idiomaDefecto" => "es" "Traduccion" => array:1 [ "en" => array:9 [ "pii" => "S1578219015000281" "doi" => "10.1016/j.adengl.2015.01.015" "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:1 [ "total" => 0 ] "idiomaDefecto" => "en" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219015000281?idApp=UINPBA000044" ] ] "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0001731014004074?idApp=UINPBA000044" "url" => "/00017310/0000010600000003/v3_202209240525/S0001731014004074/v3_202209240525/es/main.assets" ] ] "itemSiguiente" => array:20 [ "pii" => "S1578219015000293" "issn" => "15782190" "doi" => "10.1016/j.adengl.2015.01.016" "estado" => "S300" "fechaPublicacion" => "2015-04-01" "aid" => "1056" "copyright" => "Elsevier España, S.L.U. and AEDV" "documento" => "simple-article" "crossmark" => 1 "licencia" => "http://creativecommons.org/licenses/by-nc-nd/4.0/" "subdocumento" => "cor" "cita" => "Actas Dermosifiliogr. 2015;106:243-5" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 1455 "formatos" => array:3 [ "EPUB" => 53 "HTML" => 773 "PDF" => 629 ] ] "en" => array:11 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Case for Diagnosis</span>" "titulo" => "Morphea Following Radiation Therapy in a Patient With Breast Cancer" "tienePdf" => "en" "tieneTextoCompleto" => "en" "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "243" "paginaFinal" => "245" ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Morfea tras radioterapia en paciente con cáncer de mama" ] ] "contieneTextoCompleto" => array:1 [ "en" => true ] "contienePdf" => array:1 [ "en" => true ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:7 [ "identificador" => "fig0005" "etiqueta" => "Figure 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 2001 "Ancho" => 1501 "Tamanyo" => 261546 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Notable reduction in left breast size. The plaque is highly indurated and well-demarcated. The skin surface is shiny, some areas are hyperpigmented while others are pearly, and adnexal structures are absent. Note the erythematous border surrounding the entire plaque.</p>" ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "M. García-Arpa, E. Lozano-Martín, C. Ramos-Rodríguez, M. Rodríguez-Vázquez" "autores" => array:4 [ 0 => array:2 [ "nombre" => "M." "apellidos" => "García-Arpa" ] 1 => array:2 [ "nombre" => "E." "apellidos" => "Lozano-Martín" ] 2 => array:2 [ "nombre" => "C." "apellidos" => "Ramos-Rodríguez" ] 3 => array:2 [ "nombre" => "M." "apellidos" => "Rodríguez-Vázquez" ] ] ] ] ] "idiomaDefecto" => "en" "Traduccion" => array:1 [ "es" => array:9 [ "pii" => "S0001731014004153" "doi" => "10.1016/j.ad.2014.07.005" "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:1 [ "total" => 0 ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0001731014004153?idApp=UINPBA000044" ] ] "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219015000293?idApp=UINPBA000044" "url" => "/15782190/0000010600000003/v3_202209240641/S1578219015000293/v3_202209240641/en/main.assets" ] "itemAnterior" => array:20 [ "pii" => "S157821901500027X" "issn" => "15782190" "doi" => "10.1016/j.adengl.2015.01.014" "estado" => "S300" "fechaPublicacion" => "2015-04-01" "aid" => "1047" "copyright" => "Elsevier España, S.L.U. and AEDV" "documento" => "simple-article" "crossmark" => 1 "licencia" => "http://creativecommons.org/licenses/by-nc-nd/4.0/" "subdocumento" => "cor" "cita" => "Actas Dermosifiliogr. 2015;106:240-1" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 2038 "formatos" => array:3 [ "EPUB" => 52 "HTML" => 1174 "PDF" => 812 ] ] "en" => array:11 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Case and Research Letters</span>" "titulo" => "Successful Treatment of Disseminated Granuloma Annulare With Narrowband UV-B Phototherapy" "tienePdf" => "en" "tieneTextoCompleto" => "en" "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "240" "paginaFinal" => "241" ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Resolución de granuloma anular diseminado con fototerapia UVB de banda estrecha" ] ] "contieneTextoCompleto" => array:1 [ "en" => true ] "contienePdf" => array:1 [ "en" => true ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:7 [ "identificador" => "fig0010" "etiqueta" => "Figure 2" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr2.jpeg" "Alto" => 1121 "Ancho" => 2501 "Tamanyo" => 243708 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">A and B, Right thigh and lumbar region after 27 treatment sessions.</p>" ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "G. Solano-López, M.J. Concha-Garzón, D. de Argila, E. Daudén" "autores" => array:4 [ 0 => array:2 [ "nombre" => "G." "apellidos" => "Solano-López" ] 1 => array:2 [ "nombre" => "M.J." "apellidos" => "Concha-Garzón" ] 2 => array:2 [ "nombre" => "D." "apellidos" => "de Argila" ] 3 => array:2 [ "nombre" => "E." "apellidos" => "Daudén" ] ] ] ] ] "idiomaDefecto" => "en" "Traduccion" => array:1 [ "es" => array:9 [ "pii" => "S0001731014004062" "doi" => "10.1016/j.ad.2014.08.004" "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:1 [ "total" => 0 ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0001731014004062?idApp=UINPBA000044" ] ] "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S157821901500027X?idApp=UINPBA000044" "url" => "/15782190/0000010600000003/v3_202209240641/S157821901500027X/v3_202209240641/en/main.assets" ] "en" => array:15 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Case and Research Letters</span>" "titulo" => "A Tumor in Images: Anetodermic Pilomatrixoma" "tieneTextoCompleto" => true "saludo" => "To the Editor:" "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "241" "paginaFinal" => "243" ] ] "autores" => array:1 [ 0 => array:4 [ "autoresLista" => "C. Martínez-Morán, B. Echeverría-García, L. Nájera, J. Borbujo" "autores" => array:4 [ 0 => array:4 [ "nombre" => "C." "apellidos" => "Martínez-Morán" "email" => array:2 [ 0 => "crismmoran@hotmail.com" 1 => "cmmoran@salud.madrid.org" ] "referencia" => array:2 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] 1 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">*</span>" "identificador" => "cor0005" ] ] ] 1 => array:3 [ "nombre" => "B." "apellidos" => "Echeverría-García" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] ] ] 2 => array:3 [ "nombre" => "L." "apellidos" => "Nájera" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff0010" ] ] ] 3 => array:3 [ "nombre" => "J." "apellidos" => "Borbujo" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] ] ] ] "afiliaciones" => array:2 [ 0 => array:3 [ "entidad" => "Servicio de Dermatología, Hospital Universitario de Fuenlabrada, Madrid, Spain" "etiqueta" => "a" "identificador" => "aff0005" ] 1 => array:3 [ "entidad" => "Servicio de Anatomía Patológica, Hospital Universitario de Fuenlabrada, Madrid, Spain" "etiqueta" => "b" "identificador" => "aff0010" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "⁎" "correspondencia" => "Corresponding author." ] ] ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Un tumor en imágenes: pilomatrixoma anetodérmico" ] ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:7 [ "identificador" => "fig0010" "etiqueta" => "Figure 2" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr2.jpeg" "Alto" => 1584 "Ancho" => 1584 "Tamanyo" => 177985 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Dermatoscopic image showing a lesion with homogeneous red areas, irregular while-yellow structures, areas covered with a blue-white veil, irregular linear vessels on the periphery, and some chrysalides.</p>" ] ] ] "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">Pilomatrixoma or pilomatricoma is a relatively common benign cutaneous tumor that is derived from immature cells in the matrix of the hair follicle. It presents clinically as a slow-growing solid nodular lesion. There are 2 peaks in its incidence, the first during the first 20 years of life and the second smaller peak in individuals aged 50 to 60 years. In biopsy, the anetodermic or lymphangiectatic variant shows a decrease in collagen and elastic fibers as well as dilated lymphatic vessels in the superficial dermis. Clinically, these findings are manifest as hard palpable nodules within elastic sacs or as pseudobullous lesions.</p><p id="par0010" class="elsevierStylePara elsevierViewall">A 61-year-old woman, whose only relevant condition in her medical history was an operation for breast fibroadenoma, attended the clinic for a mildly painful, rapidly growing lesion in the right frontoparietal region, next to the hairline. The lesion had appeared 1 month earlier, a few days after trauma to the region. Physical exploration showed an exophytic lesion measuring 15<span class="elsevierStyleHsp" style=""></span>mm across. This lesion was well defined and soft to the touch, of reddish and violaceous color with white-yellow patches (<a class="elsevierStyleCrossRef" href="#fig0005">Figure 1</a>). The dermatoscopic image showed a lesion with homogeneous red areas, irregular white-yellow structures, areas covered with a blue-white veil, irregular linear vessels, and some chrysalides (<a class="elsevierStyleCrossRef" href="#fig0010">Figure 2</a>). Skin ultrasound showed a hypoechoic, lobulated lesion in the superficial dermis, with discrete posterior reinforcement and increased perilesional vascularization (<a class="elsevierStyleCrossRef" href="#fig0015">Figure 3</a>). The lesion was completely excised under local anesthetic and sent for histopathological analysis, which confirmed the suspected diagnosis of anetodermic pilomatrixoma (<a class="elsevierStyleCrossRef" href="#fig0020">Figure 4</a>).</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><elsevierMultimedia ident="fig0010"></elsevierMultimedia><elsevierMultimedia ident="fig0015"></elsevierMultimedia><elsevierMultimedia ident="fig0020"></elsevierMultimedia><p id="par0015" class="elsevierStylePara elsevierViewall">Anetodermic pilomatrixoma is an uncommon variant of a relatively common and well-known tumor. Its etiology is not clear, but recent studies postulate that mechanical trauma could play an essential role in its development by compromising the dermal integrity and altering the vascular microenvironment.<a class="elsevierStyleCrossRef" href="#bib0045"><span class="elsevierStyleSup">1</span></a> Some authors have suggested that the trigger could be an increase in the number or activity of mast cells, which would favor elastolysis and increase epidermal proliferation of the lesion through the activation of certain cytokines.<a class="elsevierStyleCrossRef" href="#bib0050"><span class="elsevierStyleSup">2</span></a> This would also explain why some of these tumors exhibit hyperpigmentation in the basal layer due to the capacity of mast cells to activate melanocyte proliferation through certain mediators.</p><p id="par0020" class="elsevierStylePara elsevierViewall">Clinically, anetodermic pilomatrixoma presents as an excrescent tumor with a predilection for the skin of the arms and shoulders, with normal skin coloration, a hyperpigmented appearance, or a vascular appearance.<a class="elsevierStyleCrossRef" href="#bib0055"><span class="elsevierStyleSup">3</span></a> The lesions are soft on palpation and can be depressed at the center when vertical pressure is applied.</p><p id="par0025" class="elsevierStylePara elsevierViewall">If we compare the dermatoscopic characteristics of our lesion with those reported for nonanetodermic pilomatrixomas in the study by Zaballos et al.,<a class="elsevierStyleCrossRef" href="#bib0060"><span class="elsevierStyleSup">4</span></a> we find that irregular white structures, homogeneous red areas, and irregular linear vessels are common features. The dilated vessels and hemorrhages observed in pathology may correspond to the linear vessels and homogeneous reddish areas present in the dermatoscopic image.</p><p id="par0030" class="elsevierStylePara elsevierViewall">The ultrasound image of conventional pilomatrixoma shows a lesion with a hypoechoic halo and a central hyperechoic region (corresponding to calcification) that generates the posterior shadow.<a class="elsevierStyleCrossRef" href="#bib0065"><span class="elsevierStyleSup">5</span></a> In 1999, Hughes et al.<a class="elsevierStyleCrossRef" href="#bib0070"><span class="elsevierStyleSup">6</span></a> published a retrospective preoperative ultrasound study of 28 suspected conventional pilomatrixomas. In 20 of these, the ultrasound findings supported the suspected clinical diagnosis and in 16 of these 20 lesions, histological study confirmed diagnosis of pilomatrixoma. In the literature that we reviewed, we could not find a description of skin ultrasound of anetodermic pilomatrixoma.</p><p id="par0035" class="elsevierStylePara elsevierViewall">Differential diagnosis should include basal cell carcinoma (BCC) and melanoma,<a class="elsevierStyleCrossRef" href="#bib0060"><span class="elsevierStyleSup">4</span></a> and in both cases, the dermatoscopic and ultrasound studies can help in the preoperative diagnosis. From the ultrasound point of view, BCC and melanoma are also considered hypoechoic lesions. The characteristics that can help differentiate these lesions from pilomatroxima are the presence of small hyperechoic nodules in the lesion characteristic of BCC and an irregular border with abundant vascularization within the tumor in characteristic melanoma lesions.<a class="elsevierStyleCrossRefs" href="#bib0075"><span class="elsevierStyleSup">7,8</span></a></p><p id="par0040" class="elsevierStylePara elsevierViewall">In conclusion, we present the clinical description and the first dermatoscopic and ultrasound findings for anetodermic pilomatrixoma.</p></span>" "pdfFichero" => "main.pdf" "tienePdf" => true "NotaPie" => array:1 [ 0 => array:2 [ "etiqueta" => "☆" "nota" => "<p class="elsevierStyleNotepara" id="npar0005">Please cite this article as: Martínez-Morán C, Echeverría-García B, Nájera L, Borbujo J. Un tumor en imágenes: pilomatrixoma anetodérmico. Actas Dermosifiliogr. 2015;106:241–243.</p>" ] ] "multimedia" => array:4 [ 0 => array:7 [ "identificador" => "fig0005" "etiqueta" => "Figure 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 1113 "Ancho" => 1668 "Tamanyo" => 305584 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Clinical image showing a multicolor excrescent tumor measuring 15<span class="elsevierStyleHsp" style=""></span>mm across, with a well-defined border in the right frontoparietal region.</p>" ] ] 1 => array:7 [ "identificador" => "fig0010" "etiqueta" => "Figure 2" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr2.jpeg" "Alto" => 1584 "Ancho" => 1584 "Tamanyo" => 177985 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Dermatoscopic image showing a lesion with homogeneous red areas, irregular while-yellow structures, areas covered with a blue-white veil, irregular linear vessels on the periphery, and some chrysalides.</p>" ] ] 2 => array:7 [ "identificador" => "fig0015" "etiqueta" => "Figure 3" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr3.jpeg" "Alto" => 777 "Ancho" => 1668 "Tamanyo" => 97262 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">Skin ultrasound with a hypoechoic, lobulated lesion in the superficial dermis, with discrete posterior reinforcement.</p>" ] ] 3 => array:7 [ "identificador" => "fig0020" "etiqueta" => "Figure 4" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr4.jpeg" "Alto" => 946 "Ancho" => 2333 "Tamanyo" => 283501 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">Histological image. Hematoxylin-eosin<span class="elsevierStyleHsp" style=""></span>×<span class="elsevierStyleHsp" style=""></span>20. A well-delimited pilomatrixoma can be seen beneath an edematous dermis with substantial blood extravasation (A) and complete absence of elastic fibers in staining with orcein (x<span class="elsevierStyleHsp" style=""></span>100, B).</p>" ] ] ] "bibliografia" => array:2 [ "titulo" => "References" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:8 [ 0 => array:3 [ "identificador" => "bib0045" "etiqueta" => "1" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Anetodermic pilomatricoma: Molecular characteristics and trauma in the development of its bullous appearance" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "L. Li" 1 => "Y. Zeng" 2 => "K. Fang" 3 => "Y. Xiao" 4 => "H. Jin" 5 => "H. Ray" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1097/DAD.0b013e31823583f5" "Revista" => array:6 [ "tituloSerie" => "Am J Dermatopathol" "fecha" => "2012" "volumen" => "34" "paginaInicial" => "e41" "paginaFinal" => "e45" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/22307232" "web" => "Medline" ] ] ] ] ] ] ] ] 1 => array:3 [ "identificador" => "bib0050" "etiqueta" => "2" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Anetodermic pilomatricoma: Report of three cases" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "E. Nomura" 1 => "M. Otsuka" 2 => "T. Yamamoto" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1111/j.1365-4632.2011.05285.x" "Revista" => array:6 [ "tituloSerie" => "Int J Dermatol" "fecha" => "2013" "volumen" => "52" "paginaInicial" => "735" "paginaFinal" => "738" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/23679881" "web" => "Medline" ] ] ] ] ] ] ] ] 2 => array:3 [ "identificador" => "bib0055" "etiqueta" => "3" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Floppy tumor on the shoulder" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "A.A. Garrido-Ríos" 1 => "L. Nájera-Botello" 2 => "A.C. Villanueva" 3 => "C. Meseguer-Yebra" 4 => "A. Romero-Maté" 5 => "D. Martínez-Sánchez" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1111/j.1365-4632.2010.04769.x" "Revista" => array:6 [ "tituloSerie" => "Int J Dermatol" "fecha" => "2011" "volumen" => "50" "paginaInicial" => "921" "paginaFinal" => "922" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/21781060" "web" => "Medline" ] ] ] ] ] ] ] ] 3 => array:3 [ "identificador" => "bib0060" "etiqueta" => "4" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Dermoscopic findings of pilomatricomas" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "P. Zaballos" 1 => "A. Llambrich" 2 => "S. Puig" 3 => "J. Malvehy" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1159/000148248" "Revista" => array:6 [ "tituloSerie" => "Dermatology" "fecha" => "2008" "volumen" => "217" "paginaInicial" => "225" "paginaFinal" => "230" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/18663304" "web" => "Medline" ] ] ] ] ] ] ] ] 4 => array:3 [ "identificador" => "bib0065" "etiqueta" => "5" "referencia" => array:1 [ 0 => array:1 [ "referenciaCompleta" => "Echeverría-García B, Borbujo J, Alfageme F. Incorporación de la ecografía en dermatología. Actas Dermosifiliogr. 2014. En prensa." ] ] ] 5 => array:3 [ "identificador" => "bib0070" "etiqueta" => "6" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Use of ultrasonography in the diagnosis of childhood pilomatrixoma" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "J. Hughes" 1 => "A. Lam" 2 => "M. Rogers" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1046/j.1525-1470.1999.00090.x" "Revista" => array:6 [ "tituloSerie" => "Pediatr Dermatol" "fecha" => "1999" "volumen" => "16" "paginaInicial" => "341" "paginaFinal" => "344" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10571829" "web" => "Medline" ] ] ] ] ] ] ] ] 6 => array:3 [ "identificador" => "bib0075" "etiqueta" => "7" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Pilomatrixoma: unusual clinical presentation" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "R.M. Concha" 1 => "N.M.M. Farías" 2 => "A.A. Abarzúa" 3 => "M.N. Droppelmann" 4 => "B.S. González" 5 => "B.C. García" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Arch Argent Pediatr" "fecha" => "2011" "volumen" => "109" "paginaInicial" => "116" "paginaFinal" => "118" ] ] ] ] ] ] 7 => array:3 [ "identificador" => "bib0080" "etiqueta" => "8" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Multiple hypersonographic spots in basal cell carcinoma" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "H. Ushara" 1 => "K. Hayashi" 2 => "H. Koga" 3 => "T. Saida" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1111/j.1524-4725.2007.33256.x" "Revista" => array:6 [ "tituloSerie" => "Dermatol Surg" "fecha" => "2007" "volumen" => "33" "paginaInicial" => "1215" "paginaFinal" => "1219" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/17903154" "web" => "Medline" ] ] ] ] ] ] ] ] ] ] ] ] ] "idiomaDefecto" => "en" "url" => "/15782190/0000010600000003/v3_202209240641/S1578219015000281/v3_202209240641/en/main.assets" "Apartado" => array:4 [ "identificador" => "6157" "tipo" => "SECCION" "en" => array:2 [ "titulo" => "Case and Research Letters" "idiomaDefecto" => true ] "idiomaDefecto" => "en" ] "PDF" => "https://static.elsevier.es/multimedia/15782190/0000010600000003/v3_202209240641/S1578219015000281/v3_202209240641/en/main.pdf?idApp=UINPBA000044&text.app=https://actasdermo.org/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219015000281?idApp=UINPBA000044" ]
| Year/Month | Html | Total | |
|---|---|---|---|
| 2024 November | 14 | 9 | 23 |
| 2024 October | 130 | 39 | 169 |
| 2024 September | 171 | 28 | 199 |
| 2024 August | 177 | 73 | 250 |
| 2024 July | 175 | 52 | 227 |
| 2024 June | 146 | 51 | 197 |
| 2024 May | 166 | 36 | 202 |
| 2024 April | 170 | 49 | 219 |
| 2024 March | 174 | 45 | 219 |
| 2024 February | 152 | 39 | 191 |
| 2024 January | 168 | 36 | 204 |
| 2023 December | 157 | 25 | 182 |
| 2023 November | 176 | 33 | 209 |
| 2023 October | 160 | 37 | 197 |
| 2023 September | 132 | 38 | 170 |
| 2023 August | 132 | 22 | 154 |
| 2023 July | 121 | 34 | 155 |
| 2023 June | 99 | 28 | 127 |
| 2023 May | 110 | 19 | 129 |
| 2023 April | 84 | 21 | 105 |
| 2023 March | 69 | 23 | 92 |
| 2023 February | 61 | 31 | 92 |
| 2023 January | 45 | 28 | 73 |
| 2022 December | 43 | 36 | 79 |
| 2022 November | 20 | 25 | 45 |
| 2022 October | 25 | 22 | 47 |
| 2022 September | 25 | 39 | 64 |
| 2022 August | 28 | 36 | 64 |
| 2022 July | 29 | 34 | 63 |
| 2022 June | 34 | 23 | 57 |
| 2022 May | 43 | 38 | 81 |
| 2022 April | 58 | 34 | 92 |
| 2022 March | 69 | 42 | 111 |
| 2022 February | 67 | 17 | 84 |
| 2022 January | 92 | 37 | 129 |
| 2021 December | 50 | 25 | 75 |
| 2021 November | 63 | 50 | 113 |
| 2021 October | 57 | 46 | 103 |
| 2021 September | 54 | 44 | 98 |
| 2021 August | 61 | 26 | 87 |
| 2021 July | 62 | 25 | 87 |
| 2021 June | 49 | 25 | 74 |
| 2021 May | 42 | 20 | 62 |
| 2021 April | 156 | 26 | 182 |
| 2021 March | 81 | 41 | 122 |
| 2021 February | 54 | 33 | 87 |
| 2021 January | 68 | 22 | 90 |
| 2020 December | 56 | 10 | 66 |
| 2020 November | 38 | 18 | 56 |
| 2020 October | 46 | 8 | 54 |
| 2020 September | 28 | 15 | 43 |
| 2020 August | 28 | 40 | 68 |
| 2020 July | 28 | 16 | 44 |
| 2020 June | 28 | 24 | 52 |
| 2020 May | 43 | 21 | 64 |
| 2020 April | 24 | 19 | 43 |
| 2020 March | 32 | 22 | 54 |
| 2020 February | 7 | 8 | 15 |
| 2020 January | 4 | 7 | 11 |
| 2019 December | 8 | 7 | 15 |
| 2019 November | 4 | 2 | 6 |
| 2019 October | 0 | 8 | 8 |
| 2019 September | 5 | 6 | 11 |
| 2019 August | 6 | 5 | 11 |
| 2019 July | 4 | 17 | 21 |
| 2019 June | 13 | 19 | 32 |
| 2019 May | 4 | 40 | 44 |
| 2019 April | 13 | 29 | 42 |
| 2019 March | 4 | 13 | 17 |
| 2019 February | 2 | 4 | 6 |
| 2019 January | 2 | 4 | 6 |
| 2018 December | 5 | 2 | 7 |
| 2018 November | 1 | 5 | 6 |
| 2018 October | 5 | 0 | 5 |
| 2018 September | 4 | 2 | 6 |
| 2018 August | 0 | 8 | 8 |
| 2018 July | 0 | 7 | 7 |
| 2018 June | 0 | 10 | 10 |
| 2018 May | 1 | 11 | 12 |
| 2018 April | 0 | 6 | 6 |
| 2018 March | 3 | 10 | 13 |
| 2018 February | 27 | 3 | 30 |
| 2018 January | 24 | 8 | 32 |
| 2017 December | 26 | 8 | 34 |
| 2017 November | 27 | 7 | 34 |
| 2017 October | 23 | 9 | 32 |
| 2017 September | 14 | 8 | 22 |
| 2017 August | 21 | 14 | 35 |
| 2017 July | 15 | 3 | 18 |
| 2017 June | 35 | 21 | 56 |
| 2017 May | 22 | 16 | 38 |
| 2017 April | 19 | 18 | 37 |
| 2017 March | 24 | 19 | 43 |
| 2017 February | 23 | 12 | 35 |
| 2017 January | 16 | 7 | 23 |
| 2016 December | 38 | 12 | 50 |
| 2016 November | 33 | 10 | 43 |
| 2016 October | 28 | 18 | 46 |
| 2016 September | 0 | 4 | 4 |
| 2016 August | 0 | 4 | 4 |
| 2016 July | 9 | 1 | 10 |
| 2016 June | 7 | 1 | 8 |
| 2016 May | 7 | 17 | 24 |
| 2016 April | 4 | 21 | 25 |
| 2016 March | 4 | 22 | 26 |
| 2016 February | 3 | 1 | 4 |
| 2016 January | 4 | 1 | 5 |
| 2015 December | 9 | 1 | 10 |
| 2015 November | 4 | 10 | 14 |
| 2015 October | 2 | 1 | 3 |
| 2015 September | 0 | 2 | 2 |
| 2015 August | 0 | 4 | 4 |
| 2015 July | 4 | 2 | 6 |
| 2015 June | 2 | 2 | 4 |
| 2015 May | 3 | 4 | 7 |
| 2015 April | 3 | 10 | 13 |
Show all
