Case and Research Letters
Congenital Molluscum Contagiosum
Molluscum contagiosum congénito
C. Méndez, A. Vicente
, M. Suñol, M.A. González-Enseñat
Corresponding author
Sección de Dermatología y Anatomía Patológica, Hospital Universitari Sant Joan de Déu, Barcelona, Spain
Read
14857
Timeswas read the article
5806
Total PDF
9051
Total HTML
Share statistics
array:23 [ "pii" => "S1578219013002217" "issn" => "15782190" "doi" => "10.1016/j.adengl.2012.10.017" "estado" => "S300" "fechaPublicacion" => "2013-11-01" "aid" => "755" "copyright" => "Elsevier España, S.L. and AEDV" "copyrightAnyo" => "2012" "documento" => "simple-article" "crossmark" => 0 "subdocumento" => "cor" "cita" => "Actas Dermosifiliogr. 2013;104:836-7" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 5696 "formatos" => array:3 [ "EPUB" => 41 "HTML" => 3912 "PDF" => 1743 ] ] "Traduccion" => array:1 [ "es" => array:19 [ "pii" => "S0001731012004851" "issn" => "00017310" "doi" => "10.1016/j.ad.2012.10.011" "estado" => "S300" "fechaPublicacion" => "2013-11-01" "aid" => "755" "copyright" => "Elsevier España, S.L. y AEDV" "documento" => "simple-article" "crossmark" => 0 "subdocumento" => "cor" "cita" => "Actas Dermosifiliogr. 2013;104:836-7" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 4621 "formatos" => array:3 [ "EPUB" => 3 "HTML" => 3151 "PDF" => 1467 ] ] "es" => array:11 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Carta científico-clínica</span>" "titulo" => "<span class="elsevierStyleItalic">Molluscum contagiosum</span> congénito" "tienePdf" => "es" "tieneTextoCompleto" => "es" "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "836" "paginaFinal" => "837" ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Congenital Molluscum Contagiosum" ] ] "contieneTextoCompleto" => array:1 [ "es" => true ] "contienePdf" => array:1 [ "es" => true ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:7 [ "identificador" => "fig0010" "etiqueta" => "Figura 2" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr2.jpeg" "Alto" => 599 "Ancho" => 900 "Tamanyo" => 66665 ] ] "descripcion" => array:1 [ "es" => "<p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Pápula umbilicada en el hombro derecho de un neonato de 4 días.</p>" ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "C. Méndez, A. Vicente, M. Suñol, M.A. González-Enseñat" "autores" => array:4 [ 0 => array:2 [ "nombre" => "C." "apellidos" => "Méndez" ] 1 => array:2 [ "nombre" => "A." "apellidos" => "Vicente" ] 2 => array:2 [ "nombre" => "M." "apellidos" => "Suñol" ] 3 => array:2 [ "nombre" => "M.A." "apellidos" => "González-Enseñat" ] ] ] ] ] "idiomaDefecto" => "es" "Traduccion" => array:1 [ "en" => array:9 [ "pii" => "S1578219013002217" "doi" => "10.1016/j.adengl.2012.10.017" "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:1 [ "total" => 0 ] "idiomaDefecto" => "en" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219013002217?idApp=UINPBA000044" ] ] "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0001731012004851?idApp=UINPBA000044" "url" => "/00017310/0000010400000009/v1_201310240057/S0001731012004851/v1_201310240057/es/main.assets" ] ] "itemAnterior" => array:19 [ "pii" => "S1578219013002205" "issn" => "15782190" "doi" => "10.1016/j.adengl.2012.10.016" "estado" => "S300" "fechaPublicacion" => "2013-11-01" "aid" => "754" "copyright" => "Elsevier España, S.L. and AEDV" "documento" => "simple-article" "crossmark" => 0 "subdocumento" => "cor" "cita" => "Actas Dermosifiliogr. 2013;104:834-5" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 3336 "formatos" => array:3 [ "EPUB" => 39 "HTML" => 2485 "PDF" => 812 ] ] "en" => array:11 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Case and Research Letters</span>" "titulo" => "Whitish Plaque on the Soft Palate" "tienePdf" => "en" "tieneTextoCompleto" => "en" "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "834" "paginaFinal" => "835" ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Placa blanquecina en el paladar blando" ] ] "contieneTextoCompleto" => array:1 [ "en" => true ] "contienePdf" => array:1 [ "en" => true ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:7 [ "identificador" => "fig0005" "etiqueta" => "Figure 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 1001 "Ancho" => 1333 "Tamanyo" => 132461 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Irregular whitish plaque on the soft palate.</p>" ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "G. Solano-López, D. de Argila, J. Fraga, A. García-Diez" "autores" => array:4 [ 0 => array:2 [ "nombre" => "G." "apellidos" => "Solano-López" ] 1 => array:2 [ "nombre" => "D." "apellidos" => "de Argila" ] 2 => array:2 [ "nombre" => "J." "apellidos" => "Fraga" ] 3 => array:2 [ "nombre" => "A." "apellidos" => "García-Diez" ] ] ] ] ] "idiomaDefecto" => "en" "Traduccion" => array:1 [ "es" => array:9 [ "pii" => "S000173101200484X" "doi" => "10.1016/j.ad.2012.10.010" "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:1 [ "total" => 0 ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S000173101200484X?idApp=UINPBA000044" ] ] "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219013002205?idApp=UINPBA000044" "url" => "/15782190/0000010400000009/v1_201310240051/S1578219013002205/v1_201310240051/en/main.assets" ] "en" => array:16 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Case and Research Letters</span>" "titulo" => "Congenital Molluscum Contagiosum" "tieneTextoCompleto" => true "saludo" => "<span class="elsevierStyleItalic">To the Editor</span>:" "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "836" "paginaFinal" => "837" ] ] "autores" => array:1 [ 0 => array:4 [ "autoresLista" => "C. Méndez, A. Vicente, M. Suñol, M.A. González-Enseñat" "autores" => array:4 [ 0 => array:2 [ "nombre" => "C." "apellidos" => "Méndez" ] 1 => array:4 [ "nombre" => "A." "apellidos" => "Vicente" "email" => array:1 [ 0 => "Avicente@hsjdbcn.org" ] "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">¿</span>" "identificador" => "cor0005" ] ] ] 2 => array:2 [ "nombre" => "M." "apellidos" => "Suñol" ] 3 => array:2 [ "nombre" => "M.A." "apellidos" => "González-Enseñat" ] ] "afiliaciones" => array:1 [ 0 => array:2 [ "entidad" => "Sección de Dermatología y Anatomía Patológica, Hospital Universitari Sant Joan de Déu, Barcelona, Spain" "identificador" => "aff0005" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "⁎" "correspondencia" => "Corresponding author." ] ] ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "<span class="elsevierStyleItalic">Molluscum contagiosum</span> congénito" ] ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:7 [ "identificador" => "fig0010" "etiqueta" => "Figure 2" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr2.jpeg" "Alto" => 599 "Ancho" => 900 "Tamanyo" => 66665 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Umbilicated papule on the right arm of a 4-day-old neonate.</p>" ] ] ] "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">Molluscum contagiosum infection is very common in children and is one of the most frequent reasons for consultation in outpatient and hospital pediatric care.<a class="elsevierStyleCrossRef" href="#bib0005"><span class="elsevierStyleSup">1</span></a> Infection occurs as a result of direct person-to-person contact through infected skin, contact with fomites, or autoinoculation.<a class="elsevierStyleCrossRef" href="#bib0010"><span class="elsevierStyleSup">2</span></a> In adolescence and adulthood, infection may occur through sexual contact. Occurrence during the neonatal period is rare.</p><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0005">Case 1</span><p id="par0010" class="elsevierStylePara elsevierViewall">A 12-month-old girl with no relevant history born following a full-term pregnancy and vaginal delivery. The patient was brought for consultation due to 3 congenital lesions in the left occipital region. The patient's mother reported a history of molluscum contagiosum infection of the groin and the labia majora during pregnancy; the diagnosis was confirmed at the time by biopsy. An examination of the girl revealed 2 translucent umbilical papules 1 and 2 mm in diameter and another papule 4 mm in diameter with a crusted surface. The clinical suspicion of molluscum contagiosum was confirmed following curettage of the lesions (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>).</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia></span><span id="sec0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0010">Case 2</span><p id="par0015" class="elsevierStylePara elsevierViewall">A 2-year-old boy with no relevant history was brought for consultation due to a lesion on the right shoulder which had developed in the first 4 days of life and had grown over the previous months. He had been born following a full-term pregnancy and vaginal delivery. The mother was healthy and had no history of cutaneous lesions. An examination revealed a single papule 6 mm in size on the right shoulder. The papule had well-defined borders, was the color of normal skin, and had a slightly umbilicated center (<a class="elsevierStyleCrossRef" href="#fig0010">Fig. 2</a>). Based on a clinical suspicion of molluscum contagiosum, curettage was performed of the lesion following application of a topical anesthetic cream. The procedure was carried out with ease and the lesion was removed completely. The pathology findings were consistent with molluscum contagiosum (<a class="elsevierStyleCrossRef" href="#fig0015">Fig. 3</a>).</p><elsevierMultimedia ident="fig0010"></elsevierMultimedia><elsevierMultimedia ident="fig0015"></elsevierMultimedia><p id="par0020" class="elsevierStylePara elsevierViewall">Molluscum contagiosum is caused by a member of the poxvirus family, and manifests clinically as a flesh-colored or translucent, pearl-like papule with an umbilicated center measuring 1 to 5 mm in diameter.<a class="elsevierStyleCrossRef" href="#bib0015"><span class="elsevierStyleSup">3</span></a> The most frequently affected areas are the trunk, the limbs, and the scalp. The diagnosis of this disorder is clinical. A pathology study is performed only occasionally, when the diagnosis is uncertain. Histology reveals a well-defined hyperplastic lesion of the epidermis sometimes with a central crater, and, commonly, eosinophilic inclusion bodies within the keratinocytes that later become basophilic inclusion bodies as they rise in the epithelium.<a class="elsevierStyleCrossRef" href="#bib0020"><span class="elsevierStyleSup">4</span></a> Molluscum contagiosum infection results in benign lesions that usually resolve spontaneously, although this may take months to years.<a class="elsevierStyleCrossRef" href="#bib0025"><span class="elsevierStyleSup">5</span></a> Treatment is the subject of debate. Because of the self-resolving nature of the disease, one option is no treatment. The aim of active treatment is to prevent contagion and autoinoculation. A number of treatment approaches exist, but these are all the subject of debate and none are free of risk; some examples include topical treatments (e.g., cantharidin, potassium hydroxide 5%, salicylic acid, imiquimod, tretinoin, podophyllotoxin, topical cidofovir, tincture of iodine, trichloroacetic acid) and physical treatment with cryotherapy, curettage, electrosurgery, or laser.<a class="elsevierStyleCrossRefs" href="#bib0030"><span class="elsevierStyleSup">6,7</span></a></p><p id="par0025" class="elsevierStylePara elsevierViewall">Few cases of congenital molluscum contagiosum lesions or molluscum contagiosum developing in the neonatal period have been described in the literature. A search of PubMed yielded only 9 cases of molluscum contagiosum lesions presenting congenitally or in the first days of life. In 6 of these cases the lesions were located on the scalp, with the rest appearing on the foot, the thigh, and the sacrum.<a class="elsevierStyleCrossRefs" href="#bib0015"><span class="elsevierStyleSup">3,8–10</span></a> Only the most recently published of these cases reports in the clinical history that the mother had a history of molluscum contagiosum infection.<a class="elsevierStyleCrossRef" href="#bib0050"><span class="elsevierStyleSup">10</span></a></p><p id="par0030" class="elsevierStylePara elsevierViewall">The authors of the previous cases all agree that the infection may have occurred through vertical transmission during delivery. This same mechanism is behind other viral infections such as those caused by the herpes virus and the human papillomavirus. The human papillomavirus has a long latency period from infection to clinical manifestation, potentially leading to laryngeal papillomatosis or common warts appearing years after infection; the incubation period of molluscum contagiosum, on the other hand, is quite short (2-8 weeks), thus causing the lesions to appear in the neonatal period.<a class="elsevierStyleCrossRef" href="#bib0025"><span class="elsevierStyleSup">5</span></a></p><p id="par0035" class="elsevierStylePara elsevierViewall">We have presented 2 new cases of congenital molluscum contagiosum, including a case of maternal genital infection during pregnancy and delivery. This is the second case to appear in the literature in which molluscum lesions that developed during gestation were treated and the diagnosis was confirmed by histological study. These histological findings provide firm support for the theory of vertical transmission of the virus during delivery. In the second case, the lesions appeared on the shoulder, a location not described previously. In cases where the mother's genitals are not identified as infected, transmission probably occurs through undiagnosed vaginal infection, as the poxvirus causing molluscum contagiosum may also affect the mucous membranes.</p><p id="par0040" class="elsevierStylePara elsevierViewall">It is important to consider congenital molluscum contagiosum as a possible diagnosis in neonatal patients with one or more umbilicated papules.</p></span></span>" "textoCompletoSecciones" => array:1 [ "secciones" => array:3 [ 0 => array:2 [ "identificador" => "sec0005" "titulo" => "Case 1" ] 1 => array:2 [ "identificador" => "sec0010" "titulo" => "Case 2" ] 2 => array:1 [ "titulo" => "References" ] ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "NotaPie" => array:1 [ 0 => array:2 [ "etiqueta" => "☆" "nota" => "<p class="elsevierStyleNotepara" id="npar0005">Please cite this article as: Méndez C, Vicente A, Suñol MA, González-Enseñat M. <span class="elsevierStyleItalic">Molluscum contagiosum</span> congénito. Actas Dermosifiliogr. 2013;104:836–837.</p>" ] ] "multimedia" => array:3 [ 0 => array:7 [ "identificador" => "fig0005" "etiqueta" => "Figure 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 599 "Ancho" => 900 "Tamanyo" => 186299 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Three molluscum contagiosum lesions in a newborn. Occipital region.</p>" ] ] 1 => array:7 [ "identificador" => "fig0010" "etiqueta" => "Figure 2" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr2.jpeg" "Alto" => 599 "Ancho" => 900 "Tamanyo" => 66665 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Umbilicated papule on the right arm of a 4-day-old neonate.</p>" ] ] 2 => array:7 [ "identificador" => "fig0015" "etiqueta" => "Figure 3" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr3.jpeg" "Alto" => 675 "Ancho" => 900 "Tamanyo" => 245670 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">Histopathology: molluscum contagiosum. The inclusion bodies in the keratinocytes are observed. Hematoxylin-eosin, original magnification ×10.</p>" ] ] ] "bibliografia" => array:2 [ "titulo" => "References" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:10 [ 0 => array:3 [ "identificador" => "bib0005" "etiqueta" => "1" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Épidémiologie,clinique et traitements du <span class="elsevierStyleItalic">molluscum contagiosum:</span> revue de la littérature" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "O. Vanhooteghem" 1 => "A. Henrijean" 2 => "M. de la Brassinne" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/j.annder.2008.02.004" "Revista" => array:6 [ "tituloSerie" => "Ann Dermatol Venereol" "fecha" => "2008" "volumen" => "135" "paginaInicial" => "326" "paginaFinal" => "332" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/18420087" "web" => "Medline" ] ] ] ] ] ] ] ] 1 => array:3 [ "identificador" => "bib0010" "etiqueta" => "2" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Epidemiology and impact of childhood <span class="elsevierStyleItalic">molluscum contagiosum</span>: a case series and critical review of the literature" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "A. Braue" 1 => "G. Ross" 2 => "G. Varigos" 3 => "H. Kelly" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1111/j.1525-1470.2005.22401.x" "Revista" => array:6 [ "tituloSerie" => "Pediatr Dermatol" "fecha" => "2005" "volumen" => "22" "paginaInicial" => "287" "paginaFinal" => "294" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16060861" "web" => "Medline" ] ] ] ] ] ] ] ] 2 => array:3 [ "identificador" => "bib0015" "etiqueta" => "3" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "<span class="elsevierStyleItalic">Molluscums contagiosums</span> interfessiers néonatals" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "Y. Bouyahyaou" 1 => "M. Meziane" 2 => "S. Gallouj" 3 => "O. Mikou" 4 => "F.Z. Mernissi" 5 => "I. Badioui" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/j.annder.2011.05.031" "Revista" => array:6 [ "tituloSerie" => "Ann Dermatol Venereol" "fecha" => "2011" "volumen" => "138" "paginaInicial" => "795" "paginaFinal" => "797" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/22078047" "web" => "Medline" ] ] ] ] ] ] ] ] 3 => array:3 [ "identificador" => "bib0020" "etiqueta" => "4" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Histopatología de las infecciones víricas cutáneas más frecuentes" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "L. Requena" 1 => "C. Requena" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Actas Dermosifiliogr" "fecha" => "2010" "volumen" => "101" "paginaInicial" => "201" "paginaFinal" => "216" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/20398595" "web" => "Medline" ] ] ] ] ] ] ] ] 4 => array:3 [ "identificador" => "bib0025" "etiqueta" => "5" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "<span class="elsevierStyleItalic">Molluscum contagiosum</span> from infancy to maturity" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "K. Husar" 1 => "M. Skerlev" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Clin Dermatol" "fecha" => "2002" "volumen" => "20" "paginaInicial" => "170" "paginaFinal" => "172" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11973052" "web" => "Medline" ] ] ] ] ] ] ] ] 5 => array:3 [ "identificador" => "bib0030" "etiqueta" => "6" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Tratamiento tópico con cantaradina de moluscos contagiosos" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "G. Romero" 1 => "J. Garrido" 2 => "M. Rodríguez-Veláquez" 3 => "M. García-Arpa" 4 => "P. Cortina" 5 => "B. García-Bracamonte" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Actas Dermosifiliogr" "fecha" => "2004" "volumen" => "95" "paginaInicial" => "548" "paginaFinal" => "552" ] ] ] ] ] ] 6 => array:3 [ "identificador" => "bib0035" "etiqueta" => "7" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Tratamiento mediante curetaje de moluscos contagiosos: estudio descriptivo" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "B. Monteagudo" 1 => "M. Cabanillas" 2 => "A. Acevedo" 3 => "C. de las Heras" 4 => "O. Suárez-Amor" 5 => "A. Ramírez-Santos" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/j.ad.2010.04.017" "Revista" => array:6 [ "tituloSerie" => "Actas Dermosifiliogr" "fecha" => "2011" "volumen" => "102" "paginaInicial" => "157" "paginaFinal" => "158" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/21306688" "web" => "Medline" ] ] ] ] ] ] ] ] 7 => array:3 [ "identificador" => "bib0040" "etiqueta" => "8" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "<span class="elsevierStyleItalic">Molluscum contagiosum</span> of the newborn" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "M. Mandel" 1 => "R. Lewis" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Br J Dermatol" "fecha" => "1971" "volumen" => "84" "paginaInicial" => "370" "paginaFinal" => "372" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/4102505" "web" => "Medline" ] ] ] ] ] ] ] ] 8 => array:3 [ "identificador" => "bib0045" "etiqueta" => "9" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Congenital <span class="elsevierStyleItalic">molluscum contagiosum</span>: report of four cases and review of the literature" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "C. O’Connell" 1 => "A. Oranje" 2 => "D. Van Gysel" 3 => "N. Silverberg" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1111/j.1525-1470.2008.00730.x" "Revista" => array:6 [ "tituloSerie" => "Pediatr Dermatol" "fecha" => "2008" "volumen" => "25" "paginaInicial" => "553" "paginaFinal" => "556" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/18950398" "web" => "Medline" ] ] ] ] ] ] ] ] 9 => array:3 [ "identificador" => "bib0050" "etiqueta" => "10" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Vertically transmitted <span class="elsevierStyleItalic">molluscum contagiosum</span> infection" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "J.D. Luke" 1 => "N.B. Silverberg" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1542/peds.2009-2774" "Revista" => array:6 [ "tituloSerie" => "Pediatrics" "fecha" => "2010" "volumen" => "125" "paginaInicial" => "e423" "paginaFinal" => "e425" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/20064865" "web" => "Medline" ] ] ] ] ] ] ] ] ] ] ] ] ] "idiomaDefecto" => "en" "url" => "/15782190/0000010400000009/v1_201310240051/S1578219013002217/v1_201310240051/en/main.assets" "Apartado" => array:4 [ "identificador" => "6157" "tipo" => "SECCION" "en" => array:2 [ "titulo" => "Case and Research Letters" "idiomaDefecto" => true ] "idiomaDefecto" => "en" ] "PDF" => "https://static.elsevier.es/multimedia/15782190/0000010400000009/v1_201310240051/S1578219013002217/v1_201310240051/en/main.pdf?idApp=UINPBA000044&text.app=https://actasdermo.org/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219013002217?idApp=UINPBA000044" ]
| Year/Month | Html | Total | |
|---|---|---|---|
| 2024 November | 16 | 14 | 30 |
| 2024 October | 142 | 86 | 228 |
| 2024 September | 151 | 80 | 231 |
| 2024 August | 215 | 103 | 318 |
| 2024 July | 173 | 95 | 268 |
| 2024 June | 152 | 66 | 218 |
| 2024 May | 108 | 103 | 211 |
| 2024 April | 97 | 51 | 148 |
| 2024 March | 97 | 60 | 157 |
| 2024 February | 120 | 108 | 228 |
| 2024 January | 89 | 70 | 159 |
| 2023 December | 107 | 48 | 155 |
| 2023 November | 109 | 29 | 138 |
| 2023 October | 72 | 93 | 165 |
| 2023 September | 84 | 115 | 199 |
| 2023 August | 84 | 80 | 164 |
| 2023 July | 88 | 114 | 202 |
| 2023 June | 84 | 62 | 146 |
| 2023 May | 126 | 117 | 243 |
| 2023 April | 100 | 65 | 165 |
| 2023 March | 94 | 82 | 176 |
| 2023 February | 64 | 66 | 130 |
| 2023 January | 70 | 74 | 144 |
| 2022 December | 85 | 83 | 168 |
| 2022 November | 77 | 60 | 137 |
| 2022 October | 78 | 67 | 145 |
| 2022 September | 81 | 59 | 140 |
| 2022 August | 42 | 59 | 101 |
| 2022 July | 63 | 52 | 115 |
| 2022 June | 81 | 39 | 120 |
| 2022 May | 103 | 73 | 176 |
| 2022 April | 94 | 45 | 139 |
| 2022 March | 95 | 68 | 163 |
| 2022 February | 94 | 65 | 159 |
| 2022 January | 104 | 85 | 189 |
| 2021 December | 85 | 67 | 152 |
| 2021 November | 106 | 78 | 184 |
| 2021 October | 102 | 85 | 187 |
| 2021 September | 109 | 86 | 195 |
| 2021 August | 137 | 94 | 231 |
| 2021 July | 121 | 71 | 192 |
| 2021 June | 93 | 77 | 170 |
| 2021 May | 82 | 91 | 173 |
| 2021 April | 204 | 101 | 305 |
| 2021 March | 107 | 93 | 200 |
| 2021 February | 56 | 59 | 115 |
| 2021 January | 52 | 54 | 106 |
| 2020 December | 34 | 59 | 93 |
| 2020 November | 49 | 49 | 98 |
| 2020 October | 42 | 34 | 76 |
| 2020 September | 48 | 39 | 87 |
| 2020 August | 49 | 81 | 130 |
| 2020 July | 38 | 55 | 93 |
| 2020 June | 59 | 52 | 111 |
| 2020 May | 39 | 60 | 99 |
| 2020 April | 53 | 60 | 113 |
| 2020 March | 31 | 64 | 95 |
| 2020 February | 5 | 49 | 54 |
| 2020 January | 4 | 30 | 34 |
| 2019 December | 8 | 32 | 40 |
| 2019 November | 4 | 29 | 33 |
| 2019 October | 0 | 38 | 38 |
| 2019 September | 8 | 47 | 55 |
| 2019 August | 4 | 22 | 26 |
| 2019 July | 4 | 47 | 51 |
| 2019 June | 5 | 79 | 84 |
| 2019 May | 6 | 149 | 155 |
| 2019 April | 2 | 116 | 118 |
| 2019 March | 2 | 39 | 41 |
| 2019 February | 4 | 32 | 36 |
| 2019 January | 0 | 20 | 20 |
| 2018 December | 5 | 13 | 18 |
| 2018 November | 2 | 4 | 6 |
| 2018 October | 3 | 0 | 3 |
| 2018 September | 3 | 23 | 26 |
| 2018 August | 0 | 52 | 52 |
| 2018 July | 0 | 33 | 33 |
| 2018 June | 0 | 29 | 29 |
| 2018 May | 0 | 35 | 35 |
| 2018 April | 0 | 26 | 26 |
| 2018 March | 28 | 15 | 43 |
| 2018 February | 170 | 20 | 190 |
| 2018 January | 153 | 21 | 174 |
| 2017 December | 136 | 28 | 164 |
| 2017 November | 115 | 31 | 146 |
| 2017 October | 84 | 31 | 115 |
| 2017 September | 110 | 36 | 146 |
| 2017 August | 89 | 36 | 125 |
| 2017 July | 125 | 39 | 164 |
| 2017 June | 102 | 49 | 151 |
| 2017 May | 72 | 32 | 104 |
| 2017 April | 79 | 45 | 124 |
| 2017 March | 77 | 37 | 114 |
| 2017 February | 74 | 21 | 95 |
| 2017 January | 41 | 18 | 59 |
| 2016 December | 100 | 31 | 131 |
| 2016 November | 126 | 32 | 158 |
| 2016 October | 195 | 48 | 243 |
| 2016 September | 237 | 20 | 257 |
| 2016 August | 224 | 21 | 245 |
| 2016 July | 109 | 15 | 124 |
| 2016 June | 10 | 10 | 20 |
| 2016 May | 8 | 10 | 18 |
| 2016 April | 10 | 22 | 32 |
| 2016 March | 11 | 16 | 27 |
| 2016 February | 18 | 19 | 37 |
| 2016 January | 16 | 8 | 24 |
| 2015 December | 8 | 8 | 16 |
| 2015 November | 7 | 1 | 8 |
| 2015 October | 3 | 3 | 6 |
| 2015 September | 5 | 1 | 6 |
| 2015 August | 10 | 1 | 11 |
| 2015 July | 137 | 3 | 140 |
| 2015 June | 94 | 6 | 100 |
| 2015 May | 77 | 6 | 83 |
| 2015 April | 93 | 3 | 96 |
| 2015 March | 57 | 4 | 61 |
| 2015 February | 88 | 4 | 92 |
| 2015 January | 87 | 6 | 93 |
| 2014 December | 76 | 8 | 84 |
| 2014 November | 49 | 8 | 57 |
| 2014 October | 54 | 3 | 57 |
| 2014 September | 51 | 1 | 52 |
| 2014 August | 35 | 4 | 39 |
| 2014 July | 44 | 5 | 49 |
| 2014 June | 52 | 2 | 54 |
| 2014 May | 68 | 7 | 75 |
| 2014 April | 58 | 2 | 60 |
| 2014 March | 55 | 7 | 62 |
| 2014 February | 45 | 3 | 48 |
| 2014 January | 34 | 4 | 38 |
| 2013 December | 27 | 4 | 31 |
| 2013 November | 14 | 2 | 16 |
Show all
